cucurbitacin-d and Central-Nervous-System-Neoplasms

cucurbitacin-d has been researched along with Central-Nervous-System-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for cucurbitacin-d and Central-Nervous-System-Neoplasms

ArticleYear
Cytotoxic cucurbitacin constituents from Sloanea zuliaensis.
    Journal of natural products, 2003, Volume: 66, Issue:11

    A new cucurbitacin D analogue, 2-deoxycucurbitacin D (1), as well as cucurbitacin D (2) and 25-acetylcucurbitacin F (3) were isolated from Sloanea zuliaensis. Compound 1 was found only in the young leaves of the plant and not in the mature leaves, and its structure was established using spectroscopic means. Compounds 1-3 demonstrated potent cytotoxic activity against breast (MCF-7), lung (H-460), and central nervous system (SF-268) human cancer cell lines.

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Central Nervous System Neoplasms; Drug Screening Assays, Antitumor; Elaeocarpaceae; Female; Humans; Lung Neoplasms; Molecular Structure; Panama; Plant Leaves; Plants, Medicinal; Triterpenes; Tumor Cells, Cultured

2003