cryptoxanthins has been researched along with Stomatitis* in 1 studies
1 other study(ies) available for cryptoxanthins and Stomatitis
| Article | Year |
|---|---|
Anti-Inflammatory Effects of β-Cryptoxanthin on 5-Fluorouracil-Induced Cytokine Expression in Human Oral Mucosal Keratinocytes.
Oral mucositis is a typical adverse effect of chemotherapy, causing oral pain that significantly reduces the patient's quality of life. β-cryptoxanthin (β-cry) is a carotenoid abundant in citrus fruits with antioxidant and anti-inflammatory effects. However, the β-cry effect on oral mucositis remains unclear. We investigated the effects of 5-fluorouracil (5-FU) and β-cry on human normal oral mucosal keratinocytes (hOMK). hOMK was seeded on a culture plate and cultured with 5-FU and β-cry. The cell number, mRNA expression of inflammatory cytokines and matrix metalloproteinases (MMPs), and production of inflammatory cytokines in hOMK were evaluated. Additionally, the cell count and inflammatory cytokine production were analyzed when hOMK was co-stimulated with Topics: Anti-Inflammatory Agents; Beta-Cryptoxanthin; Cytokines; Fluorouracil; Humans; Interleukin-6; Interleukin-8; Keratinocytes; Lipopolysaccharides; Matrix Metalloproteinase 9; Quality of Life; RNA, Messenger; Stomatitis | 2023 |