Page last updated: 2024-09-04

cryptotanshinone and Granulocytic Leukemia, Chronic

cryptotanshinone has been researched along with Granulocytic Leukemia, Chronic in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (85.71)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Cheng, R; Fang, Y; Ge, Y; Huang, Y; Wang, Q; Yan, M1
Chen, Z; Dong, B; Li, B; Liang, Z; Qu, L; Yang, J; Zheng, L; Zhou, H1
Chen, Z; Cheng, R; Dai, Q; Ge, Y; Xu, X; Yang, B1
Chen, Z; Cheng, RB; Ge, YQ; Huang, Z; Yang, B1
Chen, CY; Jeong, SJ; Jung, JH; Kim, JH; Kim, M; Kim, SH; Ko, SG; Kwon, TR; Lee, HJ; Lee, MH; Yun, SM1
Chu, T; Fu, HM; Jia, YQ; Li, H; Mao, SJ; Meng, WT; Shi, HY; Song, XR; Zhang, Q1
Chen, Z; Cheng, R; Dai, Q; Ge, Y; Jia, J; Liu, P; Ma, X; Peng, L; Shen, J; Wang, H; Xu, X; Zhou, Y1

Other Studies

7 other study(ies) available for cryptotanshinone and Granulocytic Leukemia, Chronic

ArticleYear
Cryptotanshinone enhances the efficacy of Bcr-Abl tyrosine kinase inhibitors via inhibiting STAT3 and eIF4E signalling pathways in chronic myeloid leukaemia.
    Pharmaceutical biology, 2021, Volume: 59, Issue:1

    Topics: Animals; Apoptosis; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; Eukaryotic Initiation Factor-4E; Female; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Nude; Phenanthrenes; Phosphorylation; Protein Kinase Inhibitors; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays

2021
Cryptotanshinone suppresses key onco-proliferative and drug-resistant pathways of chronic myeloid leukemia by targeting STAT5 and STAT3 phosphorylation.
    Science China. Life sciences, 2018, Volume: 61, Issue:9

    Topics: Antineoplastic Agents; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; Humans; Imatinib Mesylate; Interleukin-6; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Neoplastic Stem Cells; Phenanthrenes; Phosphorylation; Proto-Oncogene Proteins c-myc; STAT3 Transcription Factor; STAT5 Transcription Factor

2018
Cryptotanshinone acts synergistically with imatinib to induce apoptosis of human chronic myeloid leukemia cells.
    Leukemia & lymphoma, 2015, Volume: 56, Issue:3

    Topics: Apoptosis; Blotting, Western; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Drugs, Chinese Herbal; Eukaryotic Initiation Factor-4E; Fusion Proteins, bcr-abl; Gene Expression Regulation, Neoplastic; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Phenanthrenes; Phosphorylation; Protein Kinase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; STAT3 Transcription Factor; TOR Serine-Threonine Kinases; Tumor Cells, Cultured

2015
[Effect of cryptotanshinone on imatinib sensitivity and P-glycoprotein expression of chronic myeloid leukemia cells].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2015, Volume: 40, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caspase 3; Caspase 9; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Phenanthrenes

2015
Cryptotanshinone enhances TNF-α-induced apoptosis in chronic myeloid leukemia KBM-5 cells.
    Apoptosis : an international journal on programmed cell death, 2011, Volume: 16, Issue:7

    Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Drug Synergism; Enzyme Activation; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; MAP Kinase Kinase Kinases; NF-kappa B; Phenanthrenes; Proto-Oncogene Proteins; Reactive Oxygen Species; Signal Transduction; Tumor Necrosis Factor-alpha

2011
Growth-inhibitory and apoptosis-inducing effects of tanshinones on hematological malignancy cells and their structure-activity relationship.
    Anti-cancer drugs, 2012, Volume: 23, Issue:8

    Topics: Abietanes; Antineoplastic Agents, Phytogenic; Apoptosis; Burkitt Lymphoma; Cell Line, Tumor; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Inhibitory Concentration 50; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Microscopy, Fluorescence; Phenanthrenes; Structure-Activity Relationship; Time Factors

2012
Cryptotanshinone induces cell cycle arrest and apoptosis of multidrug resistant human chronic myeloid leukemia cells by inhibiting the activity of eukaryotic initiation factor 4E.
    Molecular and cellular biochemistry, 2012, Volume: 368, Issue:1-2

    Topics: Apoptosis; Cell Cycle Checkpoints; Cyclin D1; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Eukaryotic Initiation Factor-4E; Gene Expression Regulation, Leukemic; Gene Knockdown Techniques; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Peptide Chain Initiation, Translational; Phenanthrenes; Proto-Oncogene Proteins c-bcl-2

2012