cryptotanshinone has been researched along with Disease Models, Animal in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (13.33) | 29.6817 |
| 2010's | 15 (50.00) | 24.3611 |
| 2020's | 11 (36.67) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Bai, X; Chen, XH; Cui, WB; Fei, DQ; Liu, X; Su, PJ; Wang, DS; Wang, SS; Zhang, ZP; Zhang, ZX; Zhi, DJ | 1 |
| Agarwal, S; Chang, YM; Desai, TD; Ho, TJ; Huang, CY; Ju, DT; Kuo, WW; Liao, SC; Lin, YJ; Sun, JM; Yeh, YL | 1 |
| Bian, LH; Guo, JY; Li, J; Li, WJ; Wang, SQ; Ye, FF; Yin, Y | 1 |
| Gan, C; Li, Y; Liu, H; Tan, Z; Wang, L; Xie, Y; Yao, Y; Ye, T; Yin, W; You, J; Zhang, Q | 1 |
| Chen, X; Han, Y; Han, Z; Min, X; Pei, L; Wang, Y; Zeng, X; Zhao, W | 1 |
| Dong, J; Fan, X; Han, Y; Li, J; Li, L; Li, P; Wu, B; Zhao, Q | 1 |
| Dong, X; Li, N; Shi, D; Wang, N; Zhang, Q | 1 |
| Hu, G; Ni, X; Qi, C; Sun, Z; Wang, L; Yang, L; Yang, Y | 1 |
| He, W; Liu, T; Luo, F; Shi, G; Wu, Y; Zhang, H; Zhang, L; Zhang, Y | 1 |
| Li, D; Pang, W; Wang, H; Xu, X; You, B; Zhang, C | 1 |
| Chen, C; Chen, Z; Huang, C; Ma, J; Xu, C; Zhai, W; Zheng, J; Zhu, R | 1 |
| Cheng, L; Feng, Z; Li, H; Li, X; Lin, J; Ni, W; Wu, A; Xie, C; Zheng, W | 1 |
| Azab, KS; El Bakary, NM; El Fatih, NM; Medhat, AM; Said, MM | 1 |
| Lu, A; Qiu, W; Zhu, W | 1 |
| Feng, B; He, S; Li, C; Liu, B; Liu, H; Lu, C; Su, Z; Tang, L; Wang, X; Xu, F; Zhao, J; Zheng, G; Zheng, X; Zhu, W; Zhu, Y | 1 |
| Ding, F; Feng, J; Feng, Y; Gao, H; Huang, L; Tang, H; Xu, QM; Yang, K; Yang, S | 1 |
| Cao, Y; Chen, L; Cheng, X; Liu, F; Qi, Z; Wang, Z; Yang, Y | 1 |
| Chengxi, W; Laiyou, W; Lianbing, H; Linghao, Q; QuLiang, G; Rishuo, G | 1 |
| Suo, M; Yu, G; Zhang, M; Zhang, W | 1 |
| Han, Z; Hannifin, S; Lin, H; Liu, S; Oppenheim, JJ; Trivett, AL | 1 |
| Bai, T; Qin, C; Xu, T; Yang, K; Yu, X; Zhang, J | 1 |
| Chen, L; Wang, H; Wang, HJ; Xie, W; Yao, Y; Zhang, YS | 1 |
| Huang, Y; Li, W; Wang, CC; Wu, X; Zheng, J | 1 |
| Hong, L; Huang, F; Li, S; Liu, W; Wang, H; Wang, J; Wang, P; Zhang, X; Zhou, J | 1 |
| Chen, L; Li, F; Shu, J; Wang, H; Yao, Y; Ying, MZ; Zhang, Y | 1 |
| Choi, YH; Jeon, SJ; Kim, HP; Kim, YS; Son, KH | 1 |
| Cao, Y; Chen, S; Le, K; Liu, P; Mei, Z; Pi, R; Tang, S; Tao, L; Wang, Z; Zhang, F; Zheng, W | 1 |
| Li, XH; Wu, XK; Yang, XM | 1 |
| Cao, J; Chan, E; Chen, X; Chowbay, B; Duan, W; Li, CG; Liang, J; Lin, SG; Wen, JY; Yu, XY; Zhou, SF; Zhou, ZW | 1 |
30 other study(ies) available for cryptotanshinone and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Cryptotanshinone Alleviates Oxidative Stress and Reduces the Level of Abnormally Aggregated Protein in
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Neurodegenerative Diseases; Oxidative Stress; Phenanthrenes; Reactive Oxygen Species | 2022 |
Cryptotanshinone protects against oxidative stress in the paraquat-induced Parkinson's disease model.
Topics: Animals; Disease Models, Animal; Dopaminergic Neurons; Mice; Neuroprotective Agents; Oxidative Stress; Paraquat; Parkinson Disease | 2023 |
Cryptotanshinone regulates gut microbiota and PI3K-AKT pathway in rats to alleviate CUMS induced depressive symptoms.
Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Gastrointestinal Microbiome; Hippocampus; Molecular Docking Simulation; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Stress, Psychological | 2023 |
Cryptotanshinone reverses the epithelial-mesenchymal transformation process and attenuates bleomycin-induced pulmonary fibrosis.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Disease Models, Animal; Drugs, Chinese Herbal; Epithelial-Mesenchymal Transition; Humans; Male; Mice; Mice, Inbred C57BL; Phenanthrenes; Pulmonary Fibrosis; Rats | 2020 |
Cryptotanshinone protects dextran sulfate sodium-induced experimental ulcerative colitis in mice by inhibiting intestinal inflammation.
Topics: Animals; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Drugs, Chinese Herbal; Inflammation; Male; Mice; Phenanthrenes | 2020 |
Attenuation of doxorubicin-induced cardiotoxicity by
Topics: Animals; Apoptosis; Cardiotonic Agents; Cardiotoxicity; Computational Biology; Databases, Genetic; Disease Models, Animal; Doxorubicin; Gene Expression Profiling; Heart; Heart Diseases; Metabolic Networks and Pathways; Myocytes, Cardiac; Phenanthrenes; Rats; Reactive Oxygen Species; Signal Transduction; Transcriptome | 2020 |
Cryptotanshinone ameliorates placental oxidative stress and inflammation in mice with gestational diabetes mellitus.
Topics: Administration, Oral; Animals; Diabetes, Gestational; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Inflammation; Mice; Mice, Inbred C57BL; Oxidative Stress; Phenanthrenes; Pregnancy | 2020 |
Cryptotanshinone alleviates polycystic ovary syndrome in rats by regulating the HMGB1/TLR4/NF‑κB signaling pathway.
Topics: Animals; Body Weight; Cell Proliferation; Cell Survival; Disease Models, Animal; Female; Gene Expression Regulation; HMGB1 Protein; NF-kappa B; Organ Size; Phenanthrenes; Polycystic Ovary Syndrome; Rats; Signal Transduction; Toll-Like Receptor 4 | 2020 |
Cryptotanshinone ameliorates cardiac injury and cardiomyocyte apoptosis in rats with coronary microembolization.
Topics: Administration, Oral; Animals; Apoptosis; Cardiovascular Diseases; Disease Models, Animal; Embolism; Male; Myocytes, Cardiac; NF-kappa B; Oxidative Stress; Phenanthrenes; Rats; Rats, Sprague-Dawley; Signal Transduction | 2021 |
Cryptotanshinone Attenuates Ischemia/Reperfusion-induced Apoptosis in Myocardium by Upregulating MAPK3.
Topics: Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; Drugs, Chinese Herbal; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 3; Molecular Docking Simulation; Myocardial Reperfusion Injury; Myocytes, Cardiac; Network Pharmacology; Phenanthrenes; Salvia miltiorrhiza; Signal Transduction | 2021 |
Cryptotanshinone inhibits proliferation yet induces apoptosis by suppressing STAT3 signals in renal cell carcinoma.
Topics: Animals; Apoptosis; Carcinoma, Renal Cell; Caspase 3; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drugs, Chinese Herbal; Genes, myc; Humans; Kidney Neoplasms; Male; Mice; Models, Biological; Phenanthrenes; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays | 2017 |
Cryptotanshinone protects against IL-1β-induced inflammation in human osteoarthritis chondrocytes and ameliorates the progression of osteoarthritis in mice.
Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Chondrocytes; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Disease Progression; Female; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Middle Aged; NF-kappa B; Nitric Oxide; Osteoarthritis; Phenanthrenes; Salvia miltiorrhiza; Signal Transduction; Tumor Necrosis Factor-alpha | 2017 |
Antitumor and radiosensitizing synergistic effects of apigenin and cryptotanshinone against solid Ehrlich carcinoma in female mice.
Topics: Animals; Apigenin; Apoptosis; Carcinoma, Ehrlich Tumor; Cell Proliferation; Disease Models, Animal; Female; Gamma Rays; Humans; Mice; Phenanthrenes; Radiation-Sensitizing Agents; Whole-Body Irradiation | 2017 |
Cryptotanshinone exhibits therapeutical effects on cerebral stroke through the PI3K/AKT‑eNOS signaling pathway.
Topics: Animals; bcl-2-Associated X Protein; Disease Models, Animal; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Oncogene Protein v-akt; Phenanthrenes; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-bcl-2; Rats; Signal Transduction; Stroke | 2017 |
Cryptotanshinone reduces psoriatic epidermal hyperplasia via inhibiting the activation of STAT3.
Topics: Animals; Cell Line; Cell Proliferation; Disease Models, Animal; Drugs, Chinese Herbal; Epidermis; Humans; Hyperplasia; Imiquimod; Keratinocytes; Male; Mice, Inbred C57BL; Phenanthrenes; Psoriasis; STAT3 Transcription Factor | 2018 |
Simultaneous purification of dihydrotanshinone, tanshinone I, cryptotanshinone, and tanshinone IIA from Salvia miltiorrhiza and their anti-inflammatory activities investigation.
Topics: Abietanes; Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Chromatography, High Pressure Liquid; Cytokines; Disease Models, Animal; Kidney; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred BALB C; Nitric Oxide; Phenanthrenes; RAW 264.7 Cells; Salvia miltiorrhiza; Sepsis | 2018 |
Cryptotanshinone suppresses cell proliferation and glucose metabolism via STAT3/SIRT3 signaling pathway in ovarian cancer cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drugs, Chinese Herbal; Energy Metabolism; Female; Genes, Reporter; Glucose; Glycolysis; Humans; Mice; Ovarian Neoplasms; Phenanthrenes; Promoter Regions, Genetic; Signal Transduction; Sirtuin 3; STAT3 Transcription Factor; Xenograft Model Antitumor Assays | 2018 |
The prevention effects of cryptotanshinone nanoemulsion on postoperative peritoneal adhesions.
Topics: Animals; Cell Line; Disease Models, Animal; Emulsions; Fibrinolysis; Humans; Male; Mice; Mice, Inbred BALB C; Nanoparticles; Peritoneal Diseases; Phenanthrenes; Plasminogen Activator Inhibitor 1; Postoperative Complications; Rats; Rats, Sprague-Dawley; Surgical Procedures, Operative; Tissue Adhesions; Tissue Plasminogen Activator | 2019 |
Antinociceptive and anti-inflammatory effects of cryptotanshinone through PI3K/Akt signaling pathway in a rat model of neuropathic pain.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Interleukin-1beta; Interleukin-6; Male; Neuralgia; Phenanthrenes; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Signal Transduction; Spinal Cord Dorsal Horn; Tumor Necrosis Factor-alpha | 2019 |
Inhibition of murine hepatoma tumor growth by cryptotanshinone involves TLR7-dependent activation of macrophages and induction of adaptive antitumor immune defenses.
Topics: Adaptive Immunity; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; B7-H1 Antigen; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Liver Neoplasms; Lymphocyte Activation; Macrophages; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Phenanthrenes; Salvia miltiorrhiza; Signal Transduction; Toll-Like Receptor 7; Treatment Outcome | 2019 |
Cryptotanshinone ameliorates renal ischaemia-reperfusion injury by inhibiting apoptosis and inflammatory response.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Disease Models, Animal; Humans; Inflammation; Injections, Intraperitoneal; Kidney; Male; Mice; p38 Mitogen-Activated Protein Kinases; Phenanthrenes; Phosphorylation; Reperfusion Injury; Signal Transduction; Tumor Necrosis Factor-alpha | 2019 |
Cryptotanshinone inhibits lung tumorigenesis and induces apoptosis in cancer cells in vitro and in vivo.
Topics: Animals; Apoptosis; Body Weight; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Humans; Lung Neoplasms; Mice; Phenanthrenes; Tumor Burden; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays | 2014 |
Cryptotanshinone reverses ovarian insulin resistance in mice through activation of insulin signaling and the regulation of glucose transporters and hormone synthesizing enzymes.
Topics: Animals; Blood Glucose; Dexamethasone; Disease Models, Animal; Estradiol; Female; Gene Expression Regulation, Enzymologic; Glucose Metabolism Disorders; Glucose Transport Proteins, Facilitative; Insulin; Insulin Resistance; Mice; Ovary; Ovulation; Phenanthrenes; Phosphatidylinositol 3-Kinase; Polycystic Ovary Syndrome; Proto-Oncogene Proteins c-akt; Signal Transduction; Steroid 17-alpha-Hydroxylase; Testosterone; Tissue Culture Techniques | 2014 |
Cryptotanshinone inhibits breast cancer cell growth by suppressing estrogen receptor signaling.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Models, Molecular; Molecular Docking Simulation; Phenanthrenes; Protein Conformation; Receptors, Estrogen; Signal Transduction; Transcription, Genetic; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
Cryptotanshinone protects against adriamycin-induced mitochondrial dysfunction in cardiomyocytes.
Topics: Adenosine Triphosphate; Animals; Cardiomyopathies; Cardiotoxicity; Disease Models, Animal; Doxorubicin; Drugs, Chinese Herbal; Male; Membrane Potential, Mitochondrial; Mitochondria, Heart; Myocytes, Cardiac; Oxidative Stress; Phenanthrenes; Rats, Wistar; Salvia miltiorrhiza | 2016 |
Inhibition of prostaglandin and nitric oxide production in lipopolysaccharide-treated RAW 264.7 cells by tanshinones from the roots of Salvia miltiorrhiza bunge.
Topics: Abietanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cell Line; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Edema; Electrophoretic Mobility Shift Assay; Furans; Lipopolysaccharides; Macrophages; Male; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Phenanthrenes; Plant Roots; Quinones; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza | 2008 |
Cryptotanshinone, a compound from Salvia miltiorrhiza modulates amyloid precursor protein metabolism and attenuates beta-amyloid deposition through upregulating alpha-secretase in vivo and in vitro.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Brain; Camphanes; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Panax notoginseng; Phenanthrenes; Plaque, Amyloid; Presenilin-1; Rats; Salvia miltiorrhiza; Up-Regulation | 2009 |
[Effects of cryptotanshinone in lowering androgens synthesis for the prenatally androgenized male rats].
Topics: Androgens; Animals; Disease Models, Animal; Female; Humans; Male; Maternal Exposure; Phenanthrenes; Polycystic Ovary Syndrome; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats; Rats, Wistar | 2008 |
Transport of cryptotanshinone, a major active triterpenoid in Salvia miltiorrhiza Bunge widely used in the treatment of stroke and Alzheimer's disease, across the blood-brain barrier.
Topics: Alzheimer Disease; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Blood-Brain Barrier; Brain; Capillary Permeability; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endothelial Cells; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Knockout; Microcirculation; Multidrug Resistance-Associated Proteins; Neuroprotective Agents; Neurotoxicity Syndromes; Phenanthrenes; Plant Roots; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Stroke; Tissue Distribution; Triterpenes | 2007 |