crustacean-cardioactive-peptide and Starvation

crustacean-cardioactive-peptide has been researched along with Starvation* in 2 studies

Other Studies

2 other study(ies) available for crustacean-cardioactive-peptide and Starvation

Article	Year
CCAP regulates feeding behavior via the NPF pathway in Proceedings of the National Academy of Sciences of the United States of America, 2020, 03-31, Volume: 117, Issue:13 The intake of macronutrients is crucial for the fitness of any animal and is mainly regulated by peripheral signals to the brain. How the brain receives and translates these peripheral signals or how these interactions lead to changes in feeding behavior is not well-understood. We discovered that 2 crustacean cardioactive peptide (CCAP)-expressing neurons in Topics: Animals; Brain; Circadian Rhythm; Dopamine; Drosophila melanogaster; Drosophila Proteins; Feeding Behavior; Neurons; Neuropeptides; Signal Transduction; Starvation	2020
Brain-midgut cross-talk and autocrine metabolastat via the sNPF/CCAP negative feed-back loop in the American cockroach, Periplaneta americana. Cell and tissue research, 2015, Volume: 362, Issue:3 Immunohistochemical reactivities against short neuropeptide F (sNPF-ir) and crustacean cardioactive peptide (CCAP-ir) were detected in both the brain-subesophageal ganglion (Br-SOG) and midgut epithelial cells of the male American cockroach, Periplaneta americana. Four weeks of starvation increased the number of sNPF-ir cells and decreased the CCAP-ir cells in the Br-SOG, whereas refeeding reversed these effects. The contents of sNPF in the Br-SOG, midgut and hemolymph titer decreased in response to an injection of CCAP into the hemocoel of normally fed male cockroaches, while CCAP titers/contents decreased in response to an injection of sNPF. The results of a double-labeling experiment demonstrated that sNPF-ir co-existed in CCAP-ir cells in the pars intercerebralis (PI), dorsolateral region of protocerebrum (DL), deutocerebrum (De) and SOG. sNPF-ir and CCAP-ir were also colocalized in the midgut. sNPF and CCAP are neuropeptides and midgut factors that interact with each other. Since the two peptides are known to be secreted by identical cells that affect each other, this constitutes autocrine negative feedback regulation for a quick response to food accessibility/inaccessibility. These peptides not only constitute the switch in the digestive mechanism but also couple digestive adaptation with behavior. A CCAP injection suppressed locomotor activity when cockroaches were starved, whereas sNPF activated it when they were fed. Topics: Animals; Autocrine Communication; Brain; Cockroaches; Digestive System; Enzyme-Linked Immunosorbent Assay; Esophagus; Feedback, Physiological; Feeding Behavior; Ganglia, Invertebrate; Male; Metabolome; Motor Activity; Neuropeptides; Starvation	2015

Article

Year

CCAP regulates feeding behavior via the NPF pathway in

Proceedings of the National Academy of Sciences of the United States of America, 2020, 03-31, Volume: 117, Issue:13

The intake of macronutrients is crucial for the fitness of any animal and is mainly regulated by peripheral signals to the brain. How the brain receives and translates these peripheral signals or how these interactions lead to changes in feeding behavior is not well-understood. We discovered that 2 crustacean cardioactive peptide (CCAP)-expressing neurons in

Topics: Animals; Brain; Circadian Rhythm; Dopamine; Drosophila melanogaster; Drosophila Proteins; Feeding Behavior; Neurons; Neuropeptides; Signal Transduction; Starvation

2020

Brain-midgut cross-talk and autocrine metabolastat via the sNPF/CCAP negative feed-back loop in the American cockroach, Periplaneta americana.

Cell and tissue research, 2015, Volume: 362, Issue:3

Immunohistochemical reactivities against short neuropeptide F (sNPF-ir) and crustacean cardioactive peptide (CCAP-ir) were detected in both the brain-subesophageal ganglion (Br-SOG) and midgut epithelial cells of the male American cockroach, Periplaneta americana. Four weeks of starvation increased the number of sNPF-ir cells and decreased the CCAP-ir cells in the Br-SOG, whereas refeeding reversed these effects. The contents of sNPF in the Br-SOG, midgut and hemolymph titer decreased in response to an injection of CCAP into the hemocoel of normally fed male cockroaches, while CCAP titers/contents decreased in response to an injection of sNPF. The results of a double-labeling experiment demonstrated that sNPF-ir co-existed in CCAP-ir cells in the pars intercerebralis (PI), dorsolateral region of protocerebrum (DL), deutocerebrum (De) and SOG. sNPF-ir and CCAP-ir were also colocalized in the midgut. sNPF and CCAP are neuropeptides and midgut factors that interact with each other. Since the two peptides are known to be secreted by identical cells that affect each other, this constitutes autocrine negative feedback regulation for a quick response to food accessibility/inaccessibility. These peptides not only constitute the switch in the digestive mechanism but also couple digestive adaptation with behavior. A CCAP injection suppressed locomotor activity when cockroaches were starved, whereas sNPF activated it when they were fed.

Topics: Animals; Autocrine Communication; Brain; Cockroaches; Digestive System; Enzyme-Linked Immunosorbent Assay; Esophagus; Feedback, Physiological; Feeding Behavior; Ganglia, Invertebrate; Male; Metabolome; Motor Activity; Neuropeptides; Starvation

2015