Page last updated: 2024-10-19

croton oil and Dermatitis, Irritant

croton oil has been researched along with Dermatitis, Irritant in 13 studies

Dermatitis, Irritant: A non-allergic contact dermatitis caused by prolonged exposure to irritants and not explained by delayed hypersensitivity mechanisms.

Research Excerpts

ExcerptRelevanceReference
" Aim of the present study was to investigate the role of structurally related H4R ligands of the aminopyrimidine class with different efficacies and functionalities (neutral antagonist ST-994, partial agonist ST-1006, inverse agonist ST-1012, and partial inverse agonist ST-1124) on croton oil-induced ear edema and pruritus in mice."3.88Differential effects of functionally different histamine H ( Adami, M; Grandi, D; Micheloni, C; Stark, H, 2018)
"To investigate the topical anti-inflammatory effect of oleic acid (OA), a monounsaturated fatty acid, into Pemulen® TR2-based semisolid dosage forms, employing a croton oil-induced irritant contact dermatitis model in mice."1.62Oleic acid exhibits an expressive anti-inflammatory effect in croton oil-induced irritant contact dermatitis without the occurrence of toxicological effects in mice. ( Camponogara, C; Cruz, L; Oliveira, SM; Pegoraro, NS, 2021)
" Dose-response studies with standard contact and photocontact allergens as well as irritants and photoirritants revealed that irritants predominantly induced skin inflammation, which in turn stimulated draining lymph node cell proliferation."1.30An integrated model for the differentiation of chemical-induced allergic and irritant skin reactions. ( Ahr, HJ; Blümel, J; Homey, B; Lehmann, P; Ruzicka, T; Schuppe, HC; Vohr, HW; von Schilling, C, 1998)
"In addition, irritant dermatitis induced by 1% croton oil or 5% benzalkonium chloride was suppressed by pentoxifylline as well."1.29Pentoxifylline suppresses irritant and contact hypersensitivity reactions. ( Aragane, Y; Krone, C; Luger, TA; Neuner, P; Schwarz, A; Schwarz, T; Trautinger, F, 1993)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (30.77)18.2507
2000's5 (38.46)29.6817
2010's3 (23.08)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Pegoraro, NS1
Camponogara, C1
Cruz, L1
Oliveira, SM1
Adami, M1
Micheloni, C1
Grandi, D1
Stark, H1
Fukuyama, T1
Nakamura, Y1
Kanemaru, K1
Toyoda, C1
Jang, HJ1
Suh, PG1
Fukami, K1
Zanin, RF1
da Silva, GL1
Erig, T1
Sperotto, ND1
Leite, CE1
Coutinho-Silva, R1
Batastini, AM1
Morrone, FB1
Niwa, H1
Satoh, T1
Matsushima, Y1
Hosoya, K1
Saeki, K1
Niki, T1
Hirashima, M1
Yokozeki, H1
Scholzen, TE2
Ständer, S1
Riemann, H1
Brzoska, T1
Luger, TA3
Han, MH1
Yoon, WK1
Lee, H1
Han, SB1
Lee, K1
Park, SK1
Yang, KH1
Kim, HM1
Kang, JS1
Akiyama, H1
Kanzaki, H1
Abe, Y1
Tada, J1
Arata, J1
Schwarz, A1
Krone, C1
Trautinger, F1
Aragane, Y1
Neuner, P1
Schwarz, T1
Homey, B1
von Schilling, C1
Blümel, J1
Schuppe, HC1
Ruzicka, T1
Ahr, HJ1
Lehmann, P1
Vohr, HW1
Nelson, CJ1
How, T1
Lysle, DT1
Flint, MS1
Miller, DB1
Tinkle, SS1
Steinhoff, M1
Bonaccorsi, P1
Klein, R1
Amadesi, S1
Geppetti, P1
Lu, B1
Gerard, NP1
Olerud, JE1
Bunnett, NW1
Grady, EF1
Armstrong, CA1
Ansel, JC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Topical Silymarin Cream Versus Salicylic Acid Peeling in Treatment of Acne Vulgaris: Split Face Study[NCT04490967]Phase 430 participants (Anticipated)Interventional2021-04-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

13 other studies available for croton oil and Dermatitis, Irritant

ArticleYear
Oleic acid exhibits an expressive anti-inflammatory effect in croton oil-induced irritant contact dermatitis without the occurrence of toxicological effects in mice.
    Journal of ethnopharmacology, 2021, Mar-01, Volume: 267

    Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Croton Oil; Dermatitis, Irritant; Dise

2021
Differential effects of functionally different histamine H
    Naunyn-Schmiedeberg's archives of pharmacology, 2018, Volume: 391, Issue:12

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Croton Oil; Dermatitis, Irritant; Ear; Ligands; Ma

2018
Phospholipase Cγ1 is required for normal irritant contact dermatitis responses and sebaceous gland homeostasis.
    Experimental dermatology, 2019, Volume: 28, Issue:9

    Topics: Animals; Cell Differentiation; Cell Movement; Cell Proliferation; Croton Oil; Dermatitis, Irritant;

2019
Decrease of serum adenine nucleotide hydrolysis in an irritant contact dermatitis mice model: potential P2X7R involvement.
    Molecular and cellular biochemistry, 2015, Volume: 404, Issue:1-2

    Topics: Adenine Nucleotides; Animals; Antigens, CD; Apyrase; Croton Oil; Dermatitis, Contact; Dermatitis, Ir

2015
Stable form of galectin-9, a Tim-3 ligand, inhibits contact hypersensitivity and psoriatic reactions: a potent therapeutic tool for Th1- and/or Th17-mediated skin inflammation.
    Clinical immunology (Orlando, Fla.), 2009, Volume: 132, Issue:2

    Topics: Animals; Apoptosis; Cell Proliferation; Chemokines; Croton Oil; Cytokines; Dermatitis, Contact; Derm

2009
Modulation of cutaneous inflammation by angiotensin-converting enzyme.
    Journal of immunology (Baltimore, Md. : 1950), 2003, Apr-01, Volume: 170, Issue:7

    Topics: Administration, Cutaneous; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin

2003
Topical application of silymarin reduces chemical-induced irritant contact dermatitis in BALB/c mice.
    International immunopharmacology, 2007, Dec-15, Volume: 7, Issue:13

    Topics: Administration, Cutaneous; Animals; Cells, Cultured; Croton Oil; Dermatitis, Irritant; Dinitrochloro

2007
Staphylococcus aureus infection on experimental croton oil-inflamed skin in mice.
    Journal of dermatological science, 1994, Volume: 8, Issue:1

    Topics: Animals; Colony Count, Microbial; Croton Oil; Dermatitis, Irritant; Disease Models, Animal; Female;

1994
Pentoxifylline suppresses irritant and contact hypersensitivity reactions.
    The Journal of investigative dermatology, 1993, Volume: 101, Issue:4

    Topics: Administration, Topical; Animals; Croton Oil; Dermatitis, Contact; Dermatitis, Irritant; Dinitrofluo

1993
An integrated model for the differentiation of chemical-induced allergic and irritant skin reactions.
    Toxicology and applied pharmacology, 1998, Volume: 153, Issue:1

    Topics: Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Croton Oil; Dermatitis, Allergic Con

1998
Enhancement of the contact hypersensitivity reaction by acute morphine administration at the elicitation phase.
    Clinical immunology (Orlando, Fla.), 1999, Volume: 93, Issue:2

    Topics: Animals; Croton Oil; Dermatitis, Contact; Dermatitis, Irritant; Dinitrofluorobenzene; Ear, External;

1999
Restraint-induced modulation of allergic and irritant contact dermatitis in male and female B6.129 mice.
    Brain, behavior, and immunity, 2000, Volume: 14, Issue:4

    Topics: Animals; Corticosterone; Croton Oil; Dermatitis, Allergic Contact; Dermatitis, Irritant; Dermatologi

2000
Neutral endopeptidase terminates substance P-induced inflammation in allergic contact dermatitis.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Jan-15, Volume: 166, Issue:2

    Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability;

2001