cromolyn sodium has been researched along with Disease Models, Animal in 107 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (26.17) | 18.7374 |
| 1990's | 13 (12.15) | 18.2507 |
| 2000's | 25 (23.36) | 29.6817 |
| 2010's | 36 (33.64) | 24.3611 |
| 2020's | 5 (4.67) | 2.80 |
| Authors | Studies |
|---|---|
| Barlow, JW; Walsh, JJ | 1 |
| Beck, G; Bouchaud, G; Boumendjel, A; Boyère, C; Dumontet, C; Esmenjaud, J; Gardebien, F; Haudecoeur, R; Magnan, A; Matera, EL; Mathé, D; Mattei, E; Monneret, G; Nurisso, A; Pérès, B; Peuchmaur, M; Tourette, A | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| El-Maraghy, SA; Motawi, TK; Nady, OM; Sabry, D; Senousy, MA | 1 |
| Theoharides, TC; Tsilioni, I | 1 |
| Ambrósio, MGE; Ayupe, MC; de Oliveira, EE; de Souza, VP; Ferreira, AP; Macedo, GC; Machado, MA; Menegati, LM; Reis, DRL; Silva, FMCE | 1 |
| Ai, J; Furukawa, H; Hashimoto, T; Kuwabara, A; Lawton, MT; Sato, H; Tada, Y; Wada, K | 1 |
| Kissel, CL; Kovács, KJ; Larson, AA | 1 |
| Bergbauer, CR; Brennan, TA; Kaplan, FS; Lindborg, CM; Pignolo, RJ; Wang, H | 1 |
| Dvorakovskaya, IV; Fedin, AN; Kuzubova, NA; Lebedeva, ES; Titova, ON | 1 |
| Elmaleh, DR; Forte, AM; Griciuc, A; Hudry, E; Quinti, L; Ran, C; Shen, X; Tanzi, RE; Wan, Y; Ward, J; Zhang, C | 1 |
| Huang, S; Li, X; Lu, F; Wu, Y | 1 |
| Orozco-Suárez, SA; Rocha, L; Santana-Gómez, CE; Valle-Dorado, MG | 2 |
| Dvorakovskaya, IV; Kuzubova, NA; Lebedeva, ES; Preobrazhenskaya, TN; Surkova, EA; Titova, ON | 1 |
| Boussioutas, A; Brunnberg, J; Buchert, M; Dijkstra, C; Eissmann, MF; Ernst, M; Etemadi, N; Grimbaldeston, MA; Hibbs, ML; Huntington, ND; Jarnicki, A; Masson, F; O'Donoghue, RJJ; Phesse, T; Poh, AR; Thiem, S; Tsantikos, E | 1 |
| Chen, H; Secco, B; Shi, GP; Sjöberg, S; Sukhova, GK; Tia, V; Wang, J; Yang, M | 1 |
| Kim, DK; Kim, DS; Kim, HH; Kim, SH; Kim, SW; Lim, SH; Shin, TY | 1 |
| Fereidoni, J; Gholipoor, P; Roshan-Milani, S; Saboory, E | 1 |
| Chi, X; Hei, Z; Luo, C; Luo, G; Mao, X; Wang, Y; Xia, H; Xia, Z; Zhang, A | 1 |
| Boeckxstaens, GE; de Vries, A; Di Giovangiulio, M; Farro, G; Feyerabend, TB; Gomez-Pinilla, PJ; Liston, A; Matteoli, G; Némethova, A; Rodewald, HR; Stakenborg, N | 1 |
| Abraham, SN; Chang, JC; Duane Davis, R; Hartwig, MG; Holzknecht, ZE; Leung, J; Lin, SS; Parker, W; Tang, T | 1 |
| Altuntas, CZ; Bicer, F; Daneshgari, F; Izgi, K; Kavran, M; Ozer, A; Tuohy, VK | 1 |
| Francis, HL; Francis, TC; Graf, AB; Greene, JF; Hargrove, LA; Hodges, KM; Huynh, VD; Kennedy, LL; Meng, F; Nguyen, QP; Ueno, Y | 1 |
| Cho, H; Elmaleh, DR; Hori, Y; Hudry, E; Hyman, BT; Irimia, D; Shoup, TM; Takahashi, K; Takeda, S; Wegmann, S | 1 |
| Blum, S; Lamb, D; Thaler, E; Wex, E | 1 |
| Matsuo, H; Yokooji, T | 1 |
| Lin, J; Lin, KQ; Zhang, XM; Zhu, LB | 1 |
| El-Desoky, K; El-Shitany, NA | 1 |
| Dong, H; Li, N; Qian, Y; Sun, J; Zhang, S; Zhang, X | 1 |
| Ahmad, S; Alencar, A; da Silva, J; Ferrario, CM; Groban, L; Lin, MR; Sun, X; Wang, H; Zapata-Sudo, G | 1 |
| Banino, E; Bettati, D; Chhor, V; De Lucia, S; Degos, V; Fleiss, B; Gressens, P; Le Charpentier, T; Lebon, S; Moretti, R; Pansiot, J; Rasika, S; Schwendimann, L; Titomanlio, L | 1 |
| Bradley, C; Kreder, K; Liu, L; Liu, W; Luo, Y; Lutgendorf, S; O'Donnell, M; Schrepf, A; Wang, X | 1 |
| Hashimoto, K; Ishii, R; Kanayama, S; Matsumoto, T; Nakamura, A; Tamura, R; Ueda, Y; Yamada, Y | 1 |
| Choi, HH; Kim, CJ; Lee, JY; Moon, H; Moon, HJ; Sim, SS | 1 |
| Goto, F; Ito, N; Nakajima, K; Obata, H; Saito, S | 1 |
| Gan, XL; Hei, ZQ; Huang, PJ; Pang, HY; Wei, J | 1 |
| Kane, KA; Wainwright, CL; Walsh, SK | 1 |
| Katsuta, O; Nakamura, M; Oda, T; Shii, D; Shinomiya, K | 1 |
| Bjorling, DE; Wang, P; Wang, ZY | 1 |
| Cooper, D; Flower, RJ; Getting, SJ; Leoni, G; Perretti, M; Solito, E; Yazid, S | 1 |
| Closa, D; de-Madaria, E; Gea-Sorlí, S; Gutiérrez, LM; Lopez-Font, I; Pérez-Mateo, M | 1 |
| Kim, CJ; Kim, TD; Lee, JH; Lee, JY | 1 |
| Barragán-Iglesias, P; Castañeda-Corral, G; Godínez-Chaparro, B; Granados-Soto, V; Rocha-González, HI | 1 |
| Cornitescu, T; Dahal, BK; Ghofrani, HA; Grimminger, F; Hoffmann, J; Kaulen, C; Kosanovic, D; Kuebler, WM; Reiss, I; Savai, R; Schermuly, RT; Seeger, W; Weissmann, N | 1 |
| de Oliveira, SM; Ferreira, J; Gomez, MV; Hoffmeister, C; Rossato, MF; Trevisan, G | 1 |
| Bartelds, B; Berger, RMF; Boersma, B; Dickinson, MG; Mohaupt, S; Takens, J; van Albada, M; van Loon, RLE; Wijnberg, H | 1 |
| Dewage, L; Gan, PY; Holdsworth, SR; Kitching, AR; Ma, FT; Nikolic-Paterson, DJ; O'Sullivan, KM; Ooi, JD; Summers, SA | 1 |
| Ersoy, B; Gundogdu, C; Kucukozkan, T; Uygur, D | 1 |
| Bonneau, O; Trifilieff, A; Wyss, D | 1 |
| Arakawa, H; Koyama, H; Mayuzumi, H; Mizuno, T; Mochizuki, H; Morikawa, A; Nishimura, H; Ohki, Y; Tokuyama, K | 1 |
| Inaba, T; Shishikura, T; Shito, K; Uchida, M | 1 |
| Arshaduddin, M; Elfaki, I; Khan, HA; Moutaery, MA; Tariq, M | 1 |
| Beelen, RH; Fabbrini, P; Hekking, LH; Keuning, ED; Ter Wee, PM; van den Born, J; Zareie, M | 1 |
| Makino, T; Mizukami, H; Nose, M; Yamashita, H | 1 |
| Côté, CH; Dumont, N; Frenette, J; Lepage, K | 1 |
| Biedermann, T; Eichner, M; Haubner, R; Hültner, L; Illges, H; Kneilling, M; Krenn, V; Mailhammer, R; Morawietz, L; Pichler, BJ; Röcken, M; Sabatino, J; Solomon, S; Weber, WA | 1 |
| Marques, MJ; Minatel, E; Santo Neto, H; Ventura Machado, R | 1 |
| Jin, Y; Silverman, AJ; Vannucci, SJ | 1 |
| Lindsay, TF; Romaschin, AD; Rubin, BB; Santone, DJ; Shahani, R | 1 |
| Brain, SD; Calixto, JB; Costa, R; Fernandes, ES; Juliano, L; Lima-Garcia, JF; Manjavachi, MN; Marotta, DM; Paszcuk, AF; Quintão, NL | 1 |
| Beckmann, N; Blé, FX; Cannet, C; Fozard, JR; Karmouty-Quintana, H; Page, CP; Zurbruegg, S | 1 |
| Goto, K; Kadobe, Y; Maruyama, Y; Terasawa, M | 1 |
| Breining, T; De Vos, C; Dessy, F; Hermecz, I; Meszaros, Z | 1 |
| Richards, IM | 1 |
| Fink, JN | 1 |
| Ottenhof, M; Ufkes, JG | 1 |
| Kano, T; Koda, A; Nakamura, K; Sakamoto, K | 1 |
| Ichikawa, K; Kuriyama, K | 1 |
| Chihara, S; Hirayama, Y; Hiroi, J; Imai, T; Kishi, S; Kobayashi, K; Kohsaka, M; Sawase, K; Shigi, Y; Shimomura, K | 1 |
| Abele, C; Classen, CU; Classen, HG; Friedberg, KD; Haubold, W; Schimatschek, HF | 1 |
| Ali, AT | 1 |
| Calonge, M; Herreras, JM; Montero, JA; Pastor, JC; Ramón, JJ | 1 |
| Calixto, JB; Medeiros, YS; Saleh, TS | 1 |
| Paterson, WG | 1 |
| Kakizoe, E; Kobayashi, Y; Okunishi, H; Shirahase, H; Zhao, HF | 1 |
| Liao, H; Oz, MC; Pinsky, DJ; Vural, KM | 1 |
| Aslanis, D; Delitheos, A; Tiligada, E; Varonos, D | 1 |
| Dommergues, MA; Evrard, P; Fromont, G; Gressens, P; Mesples, B; Patkai, J; Renauld, JC; Thornton, EM | 1 |
| Alloui, A; Begon, S; Dubray, C; Eschalier, A; Mazur, A; Rayssiguier, Y | 1 |
| Orr, TS | 1 |
| Formanek, K; Kreil, G | 1 |
| Chakrin, LW; Krell, RD | 1 |
| El-Azab, J; Stewart, PB | 2 |
| Weissberg, RM | 1 |
| Garay, GL; Weissberg, RM | 1 |
| Csaba, B; Jusupova, S | 1 |
| Abboa-Offei, BE; Casey, FB | 1 |
| Kobayashi, N; Sasagawa, S; Yamatake, Y; Yanaura, S | 1 |
| Byars, NE; Ferraresi, RW | 1 |
| Bakó, L; Boros, M; Kaszaki, J; Nagy, S | 1 |
| Kadowaki, S; Umezu, K; Yamada, N | 1 |
| Iwama, T; Koda, A; Nagai, H; Suda, H | 1 |
| Imanishi, N; Morooka, S; Sugasawa, T | 1 |
| Aliaga, M; Barbara, M; Tarayre, JP; Tisne-Versailles, J; Tisseyre, N; Vieu, S | 1 |
| Calonge, MC; González, JL; Herreras, JM; Pastor, JC | 1 |
| Misawa, M; Shirakawa, Y; Takenouchi, K; Yanaura, S | 1 |
| Kamishiro, T; Misawa, M; Takenouchi, K; Yanaura, S; Yoshino, Y | 1 |
| Gould, KJ; Manners, CN; Payling, DW; Suschitzky, JL; Wells, E | 1 |
| Amatuni, VG; Matevosian, RSh | 1 |
| Johnson, HG; Sheridan, AQ | 1 |
| Eady, RP; Jackson, DM | 1 |
| Takahashi, K | 1 |
| Abiru, T; Misawa, M; Takenouchi, K; Yanaura, S; Yoshino, Y | 1 |
| Ma, JW; Wu, RS; Zhang, SM | 1 |
| Share, NN; Stotland, LM | 1 |
1 review(s) available for cromolyn sodium and Disease Models, Animal
| Article | Year |
|---|---|
Pharmacological modulation of bronchial hyperreactivity.
Topics: Animals; Asthma; Bronchi; Cromolyn Sodium; Disease Models, Animal; Humans; Mast Cells; Phosphorylation; Pollen; Proteins; Sulfur Dioxide; Vagus Nerve | 1983 |
106 other study(ies) available for cromolyn sodium and Disease Models, Animal
| Article | Year |
|---|---|
Synthesis and evaluation of 4-amino-3,4-dihydro-2H-naphthalen-1-one derivatives as mast cell stabilising and anti-inflammatory compounds.
Topics: Amides; Amines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Disease Models, Animal; Drug Evaluation, Preclinical; Ear; Edema; Mast Cells; Mice; Molecular Structure; Naphthalenes; Rats; Stereoisomerism; Structure-Activity Relationship | 2008 |
Piperidinyl-embeded chalcones possessing anti PI3Kδ inhibitory properties exhibit anti-atopic properties in preclinical models.
Topics: Animals; Asthma; Basophils; Cell Degranulation; Chalcones; Dermatitis, Atopic; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Mice; Models, Molecular; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Protein Kinase Inhibitors | 2018 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Cromolyn chitosan nanoparticles reverse the DNA methylation of RASSF1A and p16 genes and mitigate DNMT1 and METTL3 expression in breast cancer cell line and tumor xenograft model in mice.
Topics: Animals; Ascites; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Chitosan; Cromolyn Sodium; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Genes, p16; Heterografts; Humans; Mice; Nanoparticles; RNA, Neoplasm | 2022 |
Amyotrophic Lateral Sclerosis, Neuroinflammation, and Cromolyn.
Topics: Amyotrophic Lateral Sclerosis; Animals; Cromolyn Sodium; Cytokines; Disease Models, Animal; Humans; Inflammation; Mast Cells; Mice; Spinal Cord | 2020 |
Disodium cromoglycate treatment reduces T
Topics: Animals; Bone Marrow; Cromolyn Sodium; Disease Models, Animal; Eosinophilic Esophagitis; Eosinophils; Esophageal Mucosa; Fibrosis; Immunity; Lymphoid Tissue; Male; Mast Cell Stabilizers; Mast Cells; Mice; Mice, Inbred BALB C; Ovalbumin; Th2 Cells | 2020 |
Mast Cell Promotes the Development of Intracranial Aneurysm Rupture.
Topics: Aneurysm, Ruptured; Animals; Cathepsin G; Chymases; Cromolyn Sodium; Disease Models, Animal; Interleukin-6; Intracranial Aneurysm; Male; Mast Cell Stabilizers; Mast Cells; Matrix Metalloproteinase 9; Mice; Mice, Transgenic; Mutation; p-Methoxy-N-methylphenethylamine; Proto-Oncogene Proteins c-kit; Receptor, Angiotensin, Type 1; RNA, Messenger; Subarachnoid Hemorrhage; Tryptases; Tumor Necrosis Factor-alpha | 2020 |
Evidence for the modulation of nociception in mice by central mast cells.
Topics: Animals; Cell Count; Cromolyn Sodium; Disease Models, Animal; Dynorphins; Hyperalgesia; Male; Mast Cells; Mice; Nerve Growth Factor; Neurotransmitter Agents; Nociception; Nociceptors | 2017 |
Mast cell inhibition as a therapeutic approach in fibrodysplasia ossificans progressiva (FOP).
Topics: Animals; Aprepitant; Cromolyn Sodium; Disease Models, Animal; Mast Cells; Mice; Morpholines; Myositis Ossificans; Ossification, Heterotopic | 2018 |
Role of mast cells in bronchial contraction in nonallergic obstructive lung pathology.
Topics: Adenosine; Animals; Bronchi; Bronchial Hyperreactivity; Bronchoconstriction; Cell Degranulation; Cromolyn Sodium; Disease Models, Animal; Histamine; In Vitro Techniques; Male; Mast Cells; Myocytes, Smooth Muscle; Pulmonary Disease, Chronic Obstructive; Rats, Wistar; Receptors, Purinergic P1 | 2017 |
Cromolyn Reduces Levels of the Alzheimer's Disease-Associated Amyloid β-Protein by Promoting Microglial Phagocytosis.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anti-Asthmatic Agents; Brain; Cromolyn Sodium; Disease Models, Animal; Drug Combinations; Drug Repositioning; Gene Expression; Humans; Ibuprofen; Male; Mice; Mice, Transgenic; Microglia; Neurons; Neuroprotective Agents; Peptide Fragments; Phagocytosis; Transgenes | 2018 |
Disodium cromoglycate may act as a novel adjuvant for UV-attenuated Toxoplasma gondii vaccine in mouse model.
Topics: Adjuvants, Immunologic; Animals; Antibodies, Protozoan; Antigens, Protozoan; Cromolyn Sodium; Disease Models, Animal; Female; Immunity, Cellular; Immunization; Interleukin-17; Liver; Mice; Protozoan Vaccines; Random Allocation; Specific Pathogen-Free Organisms; Spleen; Th1 Cells; Th2 Cells; Toxoplasma; Toxoplasmosis, Animal; Ultraviolet Rays; Vaccines, Attenuated | 2018 |
Sodium cromoglycate reduces short- and long-term consequences of status epilepticus in rats.
Topics: Animals; Cromolyn Sodium; Dentate Gyrus; Disease Models, Animal; Hippocampus; Male; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Status Epilepticus; Time Factors | 2018 |
[EFFECT OF MAST CELL DEGRANULATION BLOCKADE ON THE INFLAMMATION OUTCOME IN THE MODEL OF OBSTRUCTIVE LUNG PATHOLOGY].
Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Cell Degranulation; Chymases; Cromolyn Sodium; Disease Models, Animal; Gene Expression Regulation; Inflammation; Lung; Male; Mast Cells; Nitrogen Dioxide; Pulmonary Disease, Chronic Obstructive; Pulmonary Surfactant-Associated Protein B; Rats; Rats, Wistar; Tryptases; Tumor Necrosis Factor-alpha | 2016 |
IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization.
Topics: Aminopyridines; Animals; Cell Degranulation; Cromolyn Sodium; Disease Models, Animal; Epithelium; Female; Gastric Mucosa; Humans; Interleukin-1 Receptor-Like 1 Protein; Interleukin-33; Macrophages; Male; Mast Cells; Mice; Mice, Transgenic; Pyrroles; Signal Transduction; Stomach Neoplasms; Tissue Array Analysis; Tumor Microenvironment | 2019 |
Pharmaceutical stabilization of mast cells attenuates experimental atherogenesis in low-density lipoprotein receptor-deficient mice.
Topics: Animals; Anti-Asthmatic Agents; Atherosclerosis; Cromolyn Sodium; Disease Models, Animal; Lipoproteins, LDL; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; p-Methoxy-N-methylphenethylamine; Receptors, LDL; Triglycerides; Vasculitis | 2013 |
Inhibitory effects of Diospyros kaki in a model of allergic inflammation: role of cAMP, calcium and nuclear factor-κB.
Topics: Animals; Anti-Asthmatic Agents; Calcium; Cell Line; Cromolyn Sodium; Diospyros; Disease Models, Animal; Histamine Release; Humans; Hypersensitivity; Inflammation; Interleukin-1beta; Interleukin-6; Male; Mast Cells; Mice; Mice, Inbred ICR; NF-kappa B; Plant Extracts; Tumor Necrosis Factor-alpha | 2013 |
Effect of hyperthermia on histamine blood level and convulsive behavior in infant rats.
Topics: Animals; Animals, Newborn; Anti-Asthmatic Agents; Body Temperature; Cromolyn Sodium; Disease Models, Animal; Female; Fever; Histamine; Male; Pregnancy; Rats; Rats, Wistar; Seizures | 2013 |
Mast cell stabilization alleviates acute lung injury after orthotopic autologous liver transplantation in rats by downregulating inflammation.
Topics: Acute Lung Injury; Animals; Cromolyn Sodium; Disease Models, Animal; Down-Regulation; Inflammation; Interleukin-1beta; Interleukin-6; Ketotifen; Liver Transplantation; Male; Mast Cells; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2013 |
Mast cells play no role in the pathogenesis of postoperative ileus induced by intestinal manipulation.
Topics: Animals; Carboxypeptidases A; Cell Degranulation; Cell Movement; Cromolyn Sodium; Digestive System Surgical Procedures; Disease Models, Animal; Gastrointestinal Transit; Gene Expression; Humans; Ileus; Inflammation; Interstitial Cells of Cajal; Mast Cells; Mice; Mice, Transgenic; Monocytes; Neutrophils; Postoperative Complications; Proto-Oncogene Proteins c-kit; Species Specificity | 2014 |
Cromolyn ameliorates acute and chronic injury in a rat lung transplant model.
Topics: Acute Lung Injury; Allografts; Animals; Anti-Asthmatic Agents; Bronchiolitis Obliterans; Chemokines; Cromolyn Sodium; Cytokines; Disease Models, Animal; Graft Rejection; Lung; Lung Injury; Lung Transplantation; Male; Mast Cells; Postoperative Complications; Rats; Rats, Inbred WKY | 2014 |
Chronic pelvic allodynia is mediated by CCL2 through mast cells in an experimental autoimmune cystitis model.
Topics: Animals; Cetirizine; Chemokine CCL2; Cromolyn Sodium; Cystitis, Interstitial; Disease Models, Animal; Female; Histamine Release; Hyperalgesia; Male; Mast Cells; Mice, Inbred BALB C; Mice, Knockout; Ranitidine; Receptors, CCR2; Urinary Bladder; Uroplakin III | 2015 |
Inhibition of mast cell-derived histamine secretion by cromolyn sodium treatment decreases biliary hyperplasia in cholestatic rodents.
Topics: Animals; Bile Ducts, Intrahepatic; Cell Proliferation; Cholestasis; Cromolyn Sodium; Disease Models, Animal; Histamine Release; Male; Mast Cells; Rats; Rats, Inbred F344 | 2014 |
A Food and Drug Administration-approved asthma therapeutic agent impacts amyloid β in the brain in a transgenic model of Alzheimer disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cells, Cultured; Cromolyn Sodium; Disease Models, Animal; Drug Approval; Flavonoids; Flavonols; Humans; Mice; Mice, Transgenic; Microglia; Microscopy, Electron, Transmission; Peptide Fragments; United States; United States Food and Drug Administration | 2015 |
A novel model of IgE-mediated passive pulmonary anaphylaxis in rats.
Topics: Aminopyridines; Anaphylaxis; Animals; Anti-Asthmatic Agents; Bronchoalveolar Lavage; Bronchoconstriction; Cell Degranulation; Cromolyn Sodium; Dinitrophenols; Disease Models, Animal; Histamine H1 Antagonists, Non-Sedating; Immunoglobulin E; Intracellular Signaling Peptides and Proteins; Loratadine; Lung; Mast Cells; Morpholines; Oxazines; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Rats; Rats, Wistar; Serum Albumin, Bovine; Syk Kinase | 2014 |
The mast cell stabilizer sodium cromoglycate reduces histamine release and status epilepticus-induced neuronal damage in the rat hippocampus.
Topics: Analysis of Variance; Animals; Anti-Asthmatic Agents; Anticonvulsants; Cell Count; Chromatography, High Pressure Liquid; Cromolyn Sodium; Disease Models, Animal; Electroencephalography; Fluoresceins; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Histamine; Male; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2015 |
Sodium Cromoglycate Prevents Exacerbation of IgE-Mediated Food-Allergic Reaction Induced by Aspirin in a Rat Model of Egg Allergy.
Topics: Administration, Oral; Allergens; Anaphylaxis; Animals; Aspirin; Cromolyn Sodium; Disease Models, Animal; Disease Progression; Egg Hypersensitivity; Immunization; Immunoglobulin E; Male; Ovalbumin; Rats | 2015 |
[Sodium cromoglycate attenuates experimental endometriosis in rats by regulating mast cells].
Topics: Animals; Cromolyn Sodium; Disease Models, Animal; Endometriosis; Endometrium; Female; Mast Cells; Nerve Growth Factor; Rats; Rats, Sprague-Dawley; Tryptases; Tumor Necrosis Factor-alpha | 2015 |
Cromoglycate, not ketotifen, ameliorated the injured effect of warm ischemia/reperfusion in rat liver: role of mast cell degranulation, oxidative stress, proinflammatory cytokine, and inducible nitric oxide synthase.
Topics: Animals; Biomarkers; Cell Degranulation; Cromolyn Sodium; Cytokines; Cytoprotection; Disease Models, Animal; Glutathione; Inflammation Mediators; Ketotifen; Lipid Peroxidation; Liver; Liver Diseases; Male; Malondialdehyde; Mast Cells; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Reperfusion Injury; Warm Ischemia | 2015 |
Cerebral mast cells contribute to postoperative cognitive dysfunction by promoting blood brain barrier disruption.
Topics: Animals; Blood-Brain Barrier; Capillary Permeability; Central Nervous System Agents; Claudin-5; Cognition Disorders; Cromolyn Sodium; Disease Models, Animal; Hippocampus; Interleukin-1beta; Male; Mast Cells; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Occludin; Postoperative Complications; Random Allocation; Rats, Sprague-Dawley; RNA, Messenger; Tibial Fractures; Tumor Necrosis Factor-alpha | 2016 |
Mast Cell Inhibition Attenuates Cardiac Remodeling and Diastolic Dysfunction in Middle-aged, Ovariectomized Fischer 344 × Brown Norway Rats.
Topics: Age Factors; Angiotensin II; Animals; Blood Pressure; Chymases; Cromolyn Sodium; Crosses, Genetic; Diastole; Disease Models, Animal; Estrogens; Female; Fibrosis; Heart Ventricles; Hypertrophy, Left Ventricular; Infusions, Subcutaneous; Mast Cells; Ovariectomy; Rats, Inbred BN; Rats, Inbred F344; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Pressure; Ventricular Remodeling | 2016 |
Contribution of mast cells to injury mechanisms in a mouse model of pediatric traumatic brain injury.
Topics: Animals; Brain Contusion; Brain Injuries, Traumatic; Caspase 3; Cell Death; Cells, Cultured; Child, Preschool; Cromolyn Sodium; Disease Models, Animal; Histamine; Humans; Infant; Mast Cells; Mice; Mice, Inbred C57BL; Microglia; Neural Stem Cells; Neurons; Proto-Oncogene Proteins c-kit; Receptors, Histamine | 2016 |
Evidence for the Role of Mast Cells in Cystitis-Associated Lower Urinary Tract Dysfunction: A Multidisciplinary Approach to the Study of Chronic Pelvic Pain Research Network Animal Model Study.
Topics: Animals; Autoimmune Diseases; Behavior, Animal; CD8-Positive T-Lymphocytes; Cells, Cultured; Cromolyn Sodium; Cystitis, Interstitial; Cytokines; Disease Models, Animal; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Transgenic; Ovalbumin; Pelvic Pain; Proto-Oncogene Proteins c-kit; RNA, Messenger; Urinary Bladder | 2016 |
Immediate-type allergic and protease-mediated reactions are involved in scratching behaviour induced by topical application of Dermatophagoides farinae extract in NC/Nga mice.
Topics: Animals; Antibodies; Antipruritics; Behavior, Animal; Capillary Permeability; Chlorpheniramine; Complex Mixtures; Cromolyn Sodium; Cytokines; Dermatitis, Atopic; Dermatophagoides farinae; Disease Models, Animal; Epidermis; Female; Gabexate; Histamine; Hypersensitivity; Immunologic Factors; Interleukins; Mast Cells; Mice; Ointments; Pruritus; Receptor, PAR-2; Serine Proteinase Inhibitors; Serotonin; Thymic Stromal Lymphopoietin | 2018 |
Quercetin inhalation inhibits the asthmatic responses by exposure to aerosolized-ovalbumin in conscious guinea-pigs.
Topics: Administration, Inhalation; Administration, Oral; Aerosols; Airway Resistance; Albuterol; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cromolyn Sodium; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Leukocytes; Lung; Male; Ovalbumin; Phospholipases A2; Quercetin; Time Factors | 2008 |
The nociceptive mechanism of 5-hydroxytryptamine released into the peripheral tissue in acute inflammatory pain in rats.
Topics: Acute Disease; Animals; Anti-Asthmatic Agents; Cromolyn Sodium; Disease Models, Animal; Dose-Response Relationship, Drug; Hindlimb; Inflammation; Male; Mast Cells; Pain; Pain Measurement; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Sensory Receptor Cells; Serotonin; Serotonin Antagonists | 2009 |
Influence of cromolyn sodium and compound 48/80 administered prior to and after reperfusion on the third day's survival rate in a rat intestinal ischemia model.
Topics: Animals; Cromolyn Sodium; Disease Models, Animal; Intestines; Mast Cells; p-Methoxy-N-methylphenethylamine; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2008 |
Mast cell degranulation--a mechanism for the anti-arrhythmic effect of endothelin-1?
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Cell Degranulation; Cromolyn Sodium; Disease Models, Animal; Electrocardiography; Endothelin-1; Heart Rate; Histamine Release; Injections, Intravenous; Male; Mast Cells; Myocardial Ischemia; p-Methoxy-N-methylphenethylamine; Rats; Rats, Sprague-Dawley; Ventricular Fibrillation; Ventricular Premature Complexes | 2009 |
Cyclosporine A eye drops inhibit the early-phase reaction in a type-I allergic conjunctivitis model in mice.
Topics: Administration, Topical; Ambrosia; Animals; Anti-Allergic Agents; Betamethasone; Capillary Permeability; Cell Degranulation; Conjunctivitis, Allergic; Cromolyn Sodium; Cyclosporine; Disease Models, Animal; Immunosuppressive Agents; Ketotifen; Male; Mast Cells; Mice; Mice, Inbred BALB C; Ophthalmic Solutions; Ovalbumin; Pruritus | 2009 |
Role of mast cells and protease-activated receptor-2 in cyclooxygenase-2 expression in urothelial cells.
Topics: Animals; Cell Communication; Cells, Cultured; Cromolyn Sodium; Cyclooxygenase 2; Cyclophosphamide; Cystitis; Disease Models, Animal; Humans; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oligopeptides; Receptor, PAR-2; RNA, Messenger; Signal Transduction; Time Factors; Up-Regulation; Urinary Bladder; Urothelium | 2009 |
Antiallergic cromones inhibit neutrophil recruitment onto vascular endothelium via annexin-A1 mobilization.
Topics: Animals; Annexin A1; Anti-Allergic Agents; Anti-Inflammatory Agents; Blotting, Western; Cell Adhesion; Cells, Cultured; Cromolyn Sodium; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Leukocyte Rolling; Male; Mesenteric Vascular Occlusion; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Microscopy, Video; Nedocromil; Neutrophils; Peritonitis; Peroxidase; Phosphorylation; Protein Kinase C; Protein Transport; Receptors, Formyl Peptide; Reperfusion Injury; Time Factors | 2010 |
Pancreatic and pulmonary mast cells activation during experimental acute pancreatitis.
Topics: Animals; Anti-Asthmatic Agents; Cell Degranulation; Cells, Cultured; Cholagogues and Choleretics; Cromolyn Sodium; Disease Models, Animal; Lung; Macrophages, Alveolar; Macrophages, Peritoneal; Male; Mast Cells; Pancreas; Pancreatitis; Rats; Rats, Wistar; Taurodeoxycholic Acid; Tumor Necrosis Factor-alpha | 2010 |
Antiasthmatic action of dibenzylbutyrolactone lignans from fruits of Forsythia viridissima on asthmatic responses to ovalbumin challenge in conscious guinea-pigs.
Topics: 4-Butyrolactone; Airway Resistance; Albuterol; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cromolyn Sodium; Dexamethasone; Disease Models, Animal; Eosinophil Peroxidase; Forsythia; Fruit; Guinea Pigs; Lignans; Male; Molecular Structure; Ovalbumin; Phospholipases A2; Plant Extracts | 2011 |
Role of peripheral 5-HT(4), 5-HT(6), and 5-HT(7) receptors in development and maintenance of secondary mechanical allodynia and hyperalgesia.
Topics: Animals; Anti-Asthmatic Agents; Area Under Curve; Cromolyn Sodium; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Formaldehyde; Hyperalgesia; Nociceptin Receptor; Pain Threshold; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Agents; Time Factors | 2011 |
Involvement of mast cells in monocrotaline-induced pulmonary hypertension in rats.
Topics: Animals; Cell Degranulation; Cromolyn Sodium; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Mast Cells; Monocrotaline; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Rats; Rats, Sprague-Dawley; Ventricular Function, Right; Ventricular Remodeling | 2011 |
Role of TRPV1 in nociception and edema induced by monosodium urate crystals in rats.
Topics: Acrylamides; Anilides; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Antioxidants; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Cinnamates; Cromolyn Sodium; Disease Models, Animal; Diterpenes; Edema; Gabexate; Histamine; Male; Mast Cells; Methysergide; Pain; Promethazine; Prostaglandin-Endoperoxide Synthases; Protein Binding; Rats; Rats, Wistar; Serine Proteinase Inhibitors; Serotonin; Serotonin Antagonists; Tritium; TRPV Cation Channels; Uric Acid | 2011 |
Mast cell inhibition improves pulmonary vascular remodeling in pulmonary hypertension.
Topics: Animals; Cell Proliferation; Chymases; Cromolyn Sodium; Disease Models, Animal; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Lung; Male; Mast Cells; Monocrotaline; Muscle, Smooth, Vascular; Neovascularization, Pathologic; Rats; Rats, Wistar; Sulfonamides; Thiophenes | 2012 |
Mast cell activation and degranulation promotes renal fibrosis in experimental unilateral ureteric obstruction.
Topics: Actins; Animals; CD4-Positive T-Lymphocytes; Cell Degranulation; Cells, Cultured; Chemokines; Collagen; Cromolyn Sodium; Disease Models, Animal; Disease Progression; Fibrosis; Gene Expression Regulation; Hydronephrosis; Kidney; Kidney Diseases; Macrophages; Male; Mast Cells; Matrix Metalloproteinase 12; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Phenotype; Proto-Oncogene Proteins c-kit; Time Factors; Transforming Growth Factor beta; Ureteral Obstruction | 2012 |
Prevention of adhesions by sodium chromoglycate, dexamethasone, saline and aprotinin after pelvic surgery.
Topics: Animals; Anti-Inflammatory Agents; Aprotinin; Cromolyn Sodium; Dexamethasone; Disease Models, Animal; Drug Therapy, Combination; Female; Hemostatics; Instillation, Drug; Peritoneal Cavity; Peritoneal Diseases; Postoperative Complications; Rabbits; Serum; Sodium Chloride; Tissue Adhesions | 2004 |
Mast cell involvement in the adenosine mediated airway hyper-reactivity in a murine model of ovalbumin-induced lung inflammation.
Topics: Adenosine-5'-(N-ethylcarboxamide); Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Budesonide; Cromolyn Sodium; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Immunization; Mast Cells; Mice; Mice, Inbred BALB C; Ovalbumin; Pneumonia; Respiratory Hypersensitivity | 2005 |
Effect of disodium cromoglycate on airway mucus secretion during antigen-induced late asthmatic responses in a murine model of asthma.
Topics: Airway Obstruction; Animals; Anti-Asthmatic Agents; Antigens; Asthma; Bronchoalveolar Lavage Fluid; Cromolyn Sodium; Disease Models, Animal; Eosinophilia; Eosinophils; Immunoglobulin E; Lung; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin | 2005 |
A late cutaneous response in actively sensitized rats: a new method for evaluating the efficacy of antiallergic drugs.
Topics: Aminopyridines; Animals; Anti-Allergic Agents; Antigens; Cromolyn Sodium; Cyclosporine; Dinitrobenzenes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Edema; Haptens; Hindlimb; Hypersensitivity, Delayed; Male; ortho-Aminobenzoates; Ovalbumin; Passive Cutaneous Anaphylaxis; Promethazine; Pyridines; Pyrimidinones; Quinolones; Rats; Rats, Wistar | 2006 |
Protective effects of nedocromil sodium and sodium cromoglycate on gastroduodenal ulcers: a comparative study in rats.
Topics: Animals; Cromolyn Sodium; Disease Models, Animal; Female; Gastric Mucosa; Male; Nedocromil; Peptic Ulcer; Protective Agents; Rats; Rats, Wistar | 2006 |
Novel role for mast cells in omental tissue remodeling and cell recruitment in experimental peritoneal dialysis.
Topics: Angiogenesis Inhibitors; Animals; Bicarbonates; Cromolyn Sodium; Dialysis Solutions; Disease Models, Animal; Lactates; Male; Mast Cells; Microcirculation; Neovascularization, Physiologic; Omentum; Peritoneal Dialysis; Rats; Rats, Inbred Strains; Vascular Endothelial Growth Factor A | 2006 |
Pharmacological characterization of a chronic pruritus model induced by multiple application of 2,4,6-trinitrochlorobenzene in NC mice.
Topics: Animals; Antipruritics; Cell Degranulation; Chronic Disease; Cromolyn Sodium; Cyproheptadine; Dermatitis, Atopic; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Immunoglobulin E; Mast Cells; Mice; Picryl Chloride; Pruritus; Tacrolimus; Terfenadine; Time Factors | 2007 |
Mast cells can modulate leukocyte accumulation and skeletal muscle function following hindlimb unloading.
Topics: Animals; Autocrine Communication; Cell Degranulation; Cromolyn Sodium; Disease Models, Animal; Female; Hindlimb Suspension; Inflammation; Macrophages; Mast Cells; Muscle Contraction; Muscle, Skeletal; Muscular Diseases; Neutrophil Infiltration; Neutrophils; p-Methoxy-N-methylphenethylamine; Rats; Rats, Wistar; Recovery of Function; Stress, Mechanical; Time Factors | 2007 |
Targeted mast cell silencing protects against joint destruction and angiogenesis in experimental arthritis in mice.
Topics: Albuterol; Animals; Antibodies, Anti-Idiotypic; Arthritis, Rheumatoid; Cromolyn Sodium; Cyclic AMP; Disease Models, Animal; Female; Glucose-6-Phosphate Isomerase; Integrin alphaVbeta3; Joint Diseases; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Mutant Strains; Neovascularization, Pathologic | 2007 |
Disodium cromoglycate protects dystrophin-deficient muscle fibers from leakiness.
Topics: Animals; Anti-Asthmatic Agents; Cell Membrane Permeability; Cromolyn Sodium; Disease Models, Animal; Dystrophin; Female; Ion Channels; Ions; Male; Mast Cells; Mice; Mice, Inbred mdx; Muscle Fibers, Skeletal; Muscle, Skeletal; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Sarcolemma; Treatment Outcome; Water-Electrolyte Balance | 2008 |
Mast cell stabilization limits hypoxic-ischemic brain damage in the immature rat.
Topics: Aging; Animals; Animals, Newborn; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Birth Injuries; Blood-Brain Barrier; Brain; Chemotaxis, Leukocyte; Cromolyn Sodium; Disease Models, Animal; Encephalitis; Endothelial Cells; Gliosis; Glucose Transporter Type 1; Hypoxia-Ischemia, Brain; Mast Cells; Rats; Rats, Wistar; Treatment Outcome | 2007 |
Mast cell stabilization improves cardiac contractile function following hemorrhagic shock and resuscitation.
Topics: Animals; beta-N-Acetylhexosaminidases; Blood Pressure; Cell Degranulation; Cromolyn Sodium; Disease Models, Animal; Ketotifen; Male; Mast Cells; Microscopy, Fluorescence; Myocardial Contraction; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left | 2008 |
Evidence for the role of neurogenic inflammation components in trypsin-elicited scratching behaviour in mice.
Topics: Anilides; Animals; Antipruritics; Behavior, Animal; Bradykinin Receptor Antagonists; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Celecoxib; Cell Degranulation; Cinnamates; Cromolyn Sodium; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dioxoles; Disease Models, Animal; Injections, Intradermal; Male; Mast Cells; Mice; Mice, Knockout; Nerve Fibers, Unmyelinated; Neurogenic Inflammation; Oligopeptides; p-Methoxy-N-methylphenethylamine; Peptide Fragments; Plant Proteins; Pruritus; Pyrazoles; Quinolines; Receptor, PAR-2; Receptors, Bradykinin; Receptors, Calcitonin Gene-Related Peptide; Reproducibility of Results; Signal Transduction; Sulfonamides; TRPV Cation Channels; Trypsin | 2008 |
In vivo pharmacological evaluation of compound 48/80-induced airways oedema by MRI.
Topics: Androstadienes; Animals; Anti-Inflammatory Agents; Aza Compounds; Benzamides; Bronchoalveolar Lavage Fluid; Budesonide; Capsaicin; Cell Degranulation; Cromolyn Sodium; Disease Models, Animal; Drug Evaluation, Preclinical; Indomethacin; Lung; Magnetic Resonance Imaging; Male; Mast Cells; Naphthoquinones; ortho-Aminobenzoates; p-Methoxy-N-methylphenethylamine; Proteins; Pulmonary Edema; Rats; Rats, Inbred BN; Respiratory System Agents; Time Factors; Wortmannin | 2008 |
Anti-anaphylactic activities of a new benzopyranopyridine derivative Y-12,141 in rats and guinea pigs.
Topics: Anaphylaxis; Animals; Asthma; Azoles; Chromones; Cromolyn Sodium; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine Release; Lung; Male; Rabbits; Rats; SRS-A; Tetrazoles | 1980 |
Pharmacology of a new orally active antiallergic: pyrido[1,2-a]pyrimidine, ucb L140 (CHINOIN 1045) in rats.
Topics: Administration, Oral; Anaphylaxis; Animals; Bronchial Spasm; Bronchodilator Agents; Cromolyn Sodium; Disease Models, Animal; Drug Interactions; Female; Guinea Pigs; Histamine Antagonists; Histamine Release; Hypersensitivity; Injections, Intraperitoneal; Injections, Intravenous; Kinetics; Male; Passive Cutaneous Anaphylaxis; Phenylhydrazines; Rats; Rats, Inbred Strains; Tachyphylaxis | 1982 |
Hypersensitivity pneumonitis.
Topics: Adrenal Cortex Hormones; Alveolitis, Extrinsic Allergic; Animals; Antigens; Cromolyn Sodium; Disease Models, Animal; Dust; Humans; Lung; Lymphocyte Activation; Lymphokines; Mice; Occupational Diseases; Precipitins; Rabbits; Rats; Therapeutic Irrigation | 1984 |
Characterization of various antiallergic agents using a new method for inducing systemic anaphylaxis in the rat.
Topics: Anaphylaxis; Animals; Blood Pressure; Bronchodilator Agents; Chromones; Cromolyn Sodium; Disease Models, Animal; Female; Hemodynamics; Hypersensitivity; Immunoglobulin E; Ketotifen; Male; Prednisolone; Pyrilamine; Rats; Rats, Inbred BN | 1984 |
Effect of 1, 3-bis (2-phenyl-4-chromenon-5-yl)-2-ol on experimental asthma in guinea pigs.
Topics: Administration, Oral; Animals; Asthma; Cromolyn Sodium; Disease Models, Animal; Guinea Pigs; Male | 1980 |
An experimental asthma model in unanesthetized rat, and the difference in effect of disodium cromoglycate between passive cutaneous anaphylaxis model and asthma model in rat.
Topics: Anaphylaxis; Animals; Asthma; Cromolyn Sodium; Disease Models, Animal; Eye; Female; Passive Cutaneous Anaphylaxis; Rats; Rats, Inbred Strains; Reagins; Respiration | 1982 |
Effects of quinotolast, a new orally active antiallergic drug, on experimental allergic models.
Topics: Administration, Oral; Anaphylaxis; Animals; Bronchoconstriction; Cells, Cultured; Cromolyn Sodium; Disease Models, Animal; Guinea Pigs; Histamine Antagonists; Histamine Release; Hypersensitivity; Leukotrienes; Male; Mast Cells; Passive Cutaneous Anaphylaxis; Quinolizines; Rats; Rats, Sprague-Dawley; Tetrazoles | 1993 |
Erythema formation in magnesium-deficient albino rats. A non-invasive model for the screening of anti-inflammatory agents and oral mineral supplements.
Topics: Animals; Anti-Inflammatory Agents; Biological Availability; Cromolyn Sodium; Diet; Disease Models, Animal; Drug Evaluation, Preclinical; Erythema; Magnesium; Magnesium Deficiency; Minerals; Omeprazole; Polyethylene Glycols; Rats; Rats, Sprague-Dawley | 1993 |
The role of nitric oxide and sulphydryls in gastric mucosal protection induced by sodium cromoglycate in rats.
Topics: Animals; Arginine; Cromolyn Sodium; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Ethylmaleimide; Gastric Mucosa; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Sulfhydryl Compounds | 1995 |
Efficacy of nedocromil sodium and cromolyn sodium in an experimental model of ocular allergy.
Topics: Albumins; Animals; Anti-Inflammatory Agents; Capillary Permeability; Conjunctivitis, Allergic; Cromolyn Sodium; Disease Models, Animal; Egg Proteins; Evans Blue; Female; Guinea Pigs; Nedocromil | 1996 |
Anti-inflammatory effects of theophylline, cromolyn and salbutamol in a murine model of pleurisy.
Topics: Albuterol; Animals; Cromolyn Sodium; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Inbred Strains; Pleurisy; Theophylline; Time Factors | 1996 |
Role of mast cell-derived mediators in acid-induced shortening of the esophagus.
Topics: Animals; Bronchodilator Agents; Constriction, Pathologic; Cromolyn Sodium; Disease Models, Animal; Electric Stimulation; Epithelium; Esophagogastric Junction; Esophagus; Female; Gastric Acid; Gastroesophageal Reflux; Histamine Release; Hydrochloric Acid; Male; Mast Cells; Muscle Contraction; Opossums; Thioxanthenes; Xanthones | 1998 |
[Effects of orally available prodrug of cromoglycic acid on collagen-induced arthritis mice].
Topics: Administration, Oral; Animals; Anti-Asthmatic Agents; Antibodies; Arthritis, Rheumatoid; Chronic Disease; Collagen; Cromolyn Sodium; Disease Models, Animal; Male; Mast Cells; Mice; Mice, Inbred DBA; Prodrugs | 1999 |
Effects of mast cell membrane stabilizing agents in a rat lung ischemia-reperfusion model.
Topics: Analysis of Variance; Animals; Anti-Asthmatic Agents; Cell Membrane; Cromolyn Sodium; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Histamine H1 Antagonists; Intercellular Adhesion Molecule-1; Ischemia; Ketotifen; Lung; Male; Mast Cells; Nitric Oxide Synthase; Phenotype; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2000 |
Changes in histamine content following pharmacologically-induced mast cell degranulation in the rat conjunctiva.
Topics: Animals; Cell Degranulation; Conjunctiva; Conjunctivitis, Allergic; Cromolyn Sodium; Disease Models, Animal; Histamine; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Rats; Rats, Wistar | 2000 |
Deleterious effects of IL-9-activated mast cells and neuroprotection by antihistamine drugs in the developing mouse brain.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain; Cerebral Palsy; Cromolyn Sodium; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Histamine H1 Antagonists; Humans; Ibotenic Acid; Infant, Newborn; Inflammation; Interleukin-9; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Neuroprotective Agents | 2001 |
Assessment of the relationship between hyperalgesia and peripheral inflammation in magnesium-deficient rats.
Topics: Animals; Anti-Inflammatory Agents; Astemizole; Cimetidine; Cromolyn Sodium; Dexamethasone; Disease Models, Animal; Estradiol; Hyperalgesia; Inflammation; Magnesium Deficiency; Male; Piroxicam; Rats; Rats, Wistar | 2002 |
The development of anti-allergic drugs.
Topics: Animals; Bronchial Spasm; Chromones; Cromolyn Sodium; Disease Models, Animal; Dogs; Dose-Response Relationship, Immunologic; Guinea Pigs; Haplorhini; Histamine H1 Antagonists; Humans; Hypersensitivity; Immunization, Passive; Lung; Mice; Passive Cutaneous Anaphylaxis; Rats | 1979 |
[Characteristics of the phlogistic action of melittin, its C-terminal fragment and some basic peptides in the rat paw (author's transl)].
Topics: Animals; Arginine; Cromolyn Sodium; Disease Models, Animal; Hindlimb; Histamine Release; Inflammation; Irritants; Lysine; Male; Melitten; Oligopeptides; Peptide Fragments; Rats; Venoms | 1975 |
An in vitro model of canine immediate-type hypersensitivity reactions.
Topics: Animals; Antigens; Ascaris; Carbachol; Cromolyn Sodium; Disease Models, Animal; Dogs; Guanidines; Histamine Release; Hot Temperature; Hypersensitivity, Immediate; Isoproterenol; Lung; Male; Papaverine; Propranolol; SRS-A | 1976 |
Pharmacologic profile of a new antiallergic compound PRD-92-Ea.
Topics: Animals; Asthma; Benzopyrans; Cromolyn Sodium; Disease Models, Animal; Haplorhini; Histamine Release; Hypersensitivity; Isoproterenol; Macaca mulatta; Male; Mast Cells; Ovalbumin; Passive Cutaneous Anaphylaxis; Rats | 1977 |
Conscious primate model for evaluating antiallergic drugs.
Topics: Albuterol; Animals; Ascaris; Cromolyn Sodium; Disease Models, Animal; Haplorhini; Histamine Release; Hypersensitivity; Isoproterenol; Macaca mulatta; Plethysmography; Prostaglandins E; Tidal Volume | 1979 |
Ascaris-induced respiratory responses in the conscious rhesus monkey.
Topics: Aerosols; Animals; Antigens; Ascaris; Cromolyn Sodium; Disease Models, Animal; Female; Haplorhini; Histamine; Isoproterenol; Lung; Macaca mulatta; Male; Tidal Volume; Time Factors | 1979 |
Effects of disodium chromoglycate on systemic anaphylaxis in guinea pigs, rats and mice.
Topics: Anaphylaxis; Animals; Cromolyn Sodium; Disease Models, Animal; Guinea Pigs; Immunity, Active; Immunity, Maternally-Acquired; Mice; Mice, Inbred BALB C; Rats | 1979 |
Pulmonary function changes in normal rats induced by antibody against rat IgE.
Topics: Animals; Antibodies, Anti-Idiotypic; Bronchial Spasm; Cromolyn Sodium; Disease Models, Animal; Dose-Response Relationship, Drug; Immunoglobulin E; Lung Compliance; Pulmonary Ventilation; Rats; Time Factors | 1979 |
Allergy induced asthma with Ascaris suum administration to dogs.
Topics: Airway Resistance; Animals; Antigen-Antibody Reactions; Antigens; Ascaris; Asthma; Atropine; Blood Pressure; Cromolyn Sodium; Disease Models, Animal; Dogs; Female; Guinea Pigs; Heart Rate; Hexamethonium Compounds; Hypersensitivity; In Vitro Techniques; Male; Rats; Respiration; Skin Tests; Toxocara; Trachea | 1977 |
The difference in effect of predosing with antiallergic compounds between the rat PCA model and the monkey asthma model. Comparison of the effects of PRD-92-Ea and disodium cromoglycate.
Topics: Administration, Oral; Animals; Asthma; Benzopyrans; Cromolyn Sodium; Cross Reactions; Disease Models, Animal; Dose-Response Relationship, Immunologic; Haplorhini; Injections, Intravenous; Macaca mulatta; Male; Passive Cutaneous Anaphylaxis; Rats; Tachyphylaxis; Time Factors | 1977 |
Intestinal anaphylaxis in the rat as a model of food allergy.
Topics: Anaphylaxis; Animals; Antigens; Capillary Permeability; Cromolyn Sodium; Cyproheptadine; Disease Models, Animal; Female; Food Hypersensitivity; Hemocyanins; Immunoglobulin E; Intestines; Mast Cells; Ovalbumin; Pertussis Vaccine; Rats | 1976 |
Studies on the relationship between xanthine oxidase and histamine release during intestinal ischemia-reperfusion.
Topics: Animals; Cromolyn Sodium; Disease Models, Animal; Dogs; Female; Guanidines; Histamine; Histamine Release; Intestines; Ischemia; Male; Mast Cells; Reperfusion Injury; Xanthine Oxidase | 1992 |
Development of an animal model of late asthmatic response in guinea pigs and effects of anti-asthmatic drugs.
Topics: Albuterol; Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cromolyn Sodium; Cytodiagnosis; Disease Models, Animal; Guinea Pigs; Immunization; Male; Respiratory Mechanics; Theophylline; Thiazoles; Time Factors | 1992 |
Effects of NZ-107 on bronchoconstriction in guinea pigs.
Topics: Albuterol; Animals; Asthma; Bronchoconstriction; Cromolyn Sodium; Disease Models, Animal; Guinea Pigs; Histamine; Hydrocortisone; Male; Metyrapone; Platelet Activating Factor; Prednisolone; Pyridazines; Respiration; Time Factors | 1992 |
Effect of the selective PAF antagonist SM-10661 on an asthmatic model. 2. Effect on antigen-induced dual asthmatic response and infiltration of leukocytes into airways in actively sensitized conscious guinea pigs.
Topics: Animals; Antigens; Asthma; Cromolyn Sodium; Disease Models, Animal; Fenoterol; Guinea Pigs; Leukocytes; Lung; Male; Ovalbumin; Platelet Activating Factor; Respiratory Function Tests; Respiratory System; Thiazoles; Thiazolidines | 1991 |
Pharmacological modulation of a model of bronchial inflammation after aerosol-induced active anaphylactic shock in conscious guinea pigs.
Topics: Albuterol; Anaphylaxis; Animals; Asthma; Bronchitis; Bronchoalveolar Lavage Fluid; Cromolyn Sodium; Dexamethasone; Disease Models, Animal; Guinea Pigs; Male; Ovalbumin; Pyrilamine | 1991 |
Pharmacologic modulation of vascular permeability in ocular allergy in the rat.
Topics: Animals; Capillary Permeability; Conjunctiva; Conjunctivitis, Allergic; Cromolyn Sodium; Dexamethasone; Disease Models, Animal; Dithiothreitol; Evans Blue; Male; Ovalbumin; Pyrilamine; Rats; Rats, Inbred Strains | 1990 |
Effects of mast cell stabilizers on a new bronchial asthma model using compound 48/80 in dogs.
Topics: Airway Resistance; Animals; Asthma; Blood Pressure; Chlorpheniramine; Cromolyn Sodium; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dogs; Histamine; Histamine H1 Antagonists; Male; Mast Cells; ortho-Aminobenzoates; p-Methoxy-N-methylphenethylamine; Vagotomy | 1987 |
Effects of antiallergic drugs on bronchial and cutaneous anaphylaxis in Lewis rats.
Topics: Anaphylaxis; Animals; Asthma; Chlorpheniramine; Cromolyn Sodium; Cyclohexanecarboxylic Acids; Disease Models, Animal; Histamine H1 Antagonists; Methysergide; ortho-Aminobenzoates; Passive Cutaneous Anaphylaxis; Rats; Rats, Inbred Lew; Ventilation-Perfusion Ratio | 1988 |
Predictive structure-activity relationships in a series of pyranoquinoline derivatives. A new primate model for the identification of antiallergic activity.
Topics: Animals; Ascariasis; Bronchoalveolar Lavage Fluid; Chemical Phenomena; Chemistry; Cromolyn Sodium; Disease Models, Animal; Histamine Release; Hypersensitivity; Immunoglobulin E; Macaca; Mast Cells; Pyrans; Quinolines; Structure-Activity Relationship | 1988 |
[Effect of preliminary administration of alpha-tocopherol and intal on the course of experimental myocardial necrosis].
Topics: Animals; Capillaries; Coronary Circulation; Coronary Disease; Cromolyn Sodium; Disease Models, Animal; Male; Myocardial Infarction; Myocardium; Necrosis; Premedication; Rats; Vitamin E | 1989 |
The characterization of lodoxamide, a very active inhibitor of mediator release, in animal and human models of asthma.
Topics: Amino Acids; Animals; Asthma; Calcium; Cromolyn Sodium; Disease Models, Animal; Drug Evaluation; Histamine H1 Antagonists; Humans; Macaca mulatta; Mast Cells; Nitriles; Oxamic Acid; Rats; Tromethamine | 1986 |
Monkeys infected with Ascaris suum (a new in vivo model of airway disease): protective effect of nedocromil sodium and sodium cromoglycate against bronchial antigen challenge.
Topics: Animals; Ascariasis; Bronchial Provocation Tests; Cromolyn Sodium; Disease Models, Animal; Female; Leukocyte Count; Macaca; Male; Nedocromil; Quinolines | 1986 |
Effects of MY-5116 on experimental asthma in rats and guinea pigs.
Topics: Animals; Asthma; Cromolyn Sodium; Disease Models, Animal; Female; Guinea Pigs; Histamine Antagonists; Male; Quinolines; Quinolones; Rats | 1986 |
Strain difference in an allergic asthma model in rats.
Topics: Animals; Asthma; Cromolyn Sodium; Disease Models, Animal; Hypersensitivity; Male; Rats; Rats, Inbred F344; Rats, Inbred Lew; Rats, Inbred Strains; Species Specificity | 1987 |
[Rat model of passive lung anaphylaxis induced by trichosanthin].
Topics: Anaphylaxis; Animals; Asthma; Cromolyn Sodium; Disease Models, Animal; Female; Lung Diseases; Male; Plant Proteins; Rats; Trichosanthin | 1985 |
Pharmacological studies on active bronchial anaphylaxis in the rat.
Topics: Aluminum Hydroxide; Anaphylaxis; Animals; Atropine; Bordetella pertussis; Bronchial Spasm; Cromolyn Sodium; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Indomethacin; Isoproterenol; Mecamylamine; Methysergide; Ovalbumin; Pressure; Propranolol; Rats; Time Factors; Trachea; Vagotomy; Vagus Nerve | 1974 |