Page last updated: 2024-08-25

cromakalim and Disease Models, Animal

cromakalim has been researched along with Disease Models, Animal in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's16 (38.10)18.2507
2000's14 (33.33)29.6817
2010's8 (19.05)24.3611
2020's4 (9.52)2.80

Authors

AuthorsStudies
Aziz, Q; Christensen, SL; Christensen, ST; Cour, S; Ernstsen, C; Guzaite, G; Hansen, TF; Janfelt, C; Jansen-Olesen, I; Kogelman, LJ; Kristensen, DM; Lauritzen, SP; Olesen, J; Rasmussen, RH; Styrishave, B; Tinker, A1
Anderson, KJ; Dosa, PI; Fautsch, MP; Holman, BH; Millar, JC; Roddy, GW; Roy Chowdhury, U1
Li, Z; Liu, X; Ren, X; Wang, W; Wang, Y; Wu, S; Zhang, K; Zhu, C1
Ashina, M; Christensen, SL; Ernstsen, C; Guo, S; Hay-Schmidt, A; Kristensen, DM; Olesen, J1
Hamlin, RL; Kijtawornrat, A; Limprasutr, V; Meedech, P; Saengklub, N1
Archondo, T; Chin, A; García-Torrent, MJ; González, P; Macaya, C; Molina-Morúa, R; Moreno, J; Pérez-Castellano, N; Pérez-Villacastín, J; Quintanilla, JG; Rodríguez-Bobada, C; Usandizaga, E1
Dong, J; Jia, X; Li, W; Liu, G; Sun, J; Tian, J; Wang, R; Wang, X; Wang, Y; Wei, L; Zhao, G1
Dehpour, AR; Ebrahimi, F; Ghasemi, M; Gholipour, T; Karimollah, AR; Nezami, BG; Shafaroodi, H1
Bortolatto, CF; Jesse, CR; Nogueira, CW; Wilhelm, EA1
Bari, F; Boda, K; Busija, DW; Domoki, F; Institoris, A; Katakam, PV; Snipes, JA1
Gao, JY; Ito, K; Ito, Y; Shimokawa, H; Shiroto, T; Tsuburaya, R; Yasuda, S1
Amrutkar, DV; Baun, M; Gupta, S; Hay-Schmidt, A; Iversen, A; Jansen-Olesen, I; Lund, TM; Olesen, J; Ploug, KB; Ramachandran, R1
Busija, DW; Erdös, B; Miller, AW1
Brioni, JD; Brune, ME; Coghlan, MJ; Fey, TA; Gopalakrishnan, M; King, LL; Strake, JG; Sullivan, JP1
Brioni, JD; Brune, ME; Coghlan, MJ; Fabiyi, AC; Gopalakrishnan, M; Lynch, JJ1
Das, B; Sarkar, C1
Endre, ZH; Gobé, GC; Rahgozar, M; Willgoss, DA1
Ghosh, M; Hanna, ST; McNeill, JR; Wang, R1
Asadi, S; Dehpour, AR; Ebrahimi, F; Ghasemi, M; Hajrasouliha, AR; Sadeghipour, H; Shafaroodi, H; Tavakoli, S1
Chen, X; Connors, SG; Mendonca, M; Patel, K; Welch, WJ; Wilcox, CS1
Hirano, T; Hisa, H; Ogasawara, A; Satoh, S1
Dux, L; Ferdinandy, P; Koltai, M; Szilvássy, Z1
Grover, GJ1
Carmint, WJ; Colatsky, TJ; Fenichel, RL; Patelunas-Hoffman, DM1
Drew, GM; Roach, AG; Trezise, DJ; Watts, IS; Weston, AH1
Imagawa, J; Kamei, K; Koga, T; Nabata, H; Sugo, I; Yoshida, S1
Chapman, ID; Cook, NS1
Brotchie, JM; Crossman, AR; Duty, S; Hille, CJ; Maneuf, YP1
Baczkó, I; Leprán, I; Papp, JG1
Koyama, T; Matsuzaki, T; Nakasone, J; Noguchi, K; Ojiri, Y; Sakanashi, M1
Abe, A; Kawazoe, C; Kondo, Y; Sato, K1
Astier, A; Baufreton, C; Bertrand, S; Fernandez, C; Garnier, JP; Kirsch, M; Loisance, D1
Du Plooy, WJ; Hay, L; Kahler, CP; Schutte, PJ1
Abe, I; Fujii, K; Fujishima, M; Goto, K; Onaka, U1
Armstead, WM1
Ambalavanan, N; Bulger, A; Philips, J; Ware, J1
Leerssen, HM; Leunissen, JD; van Opstal, JM; Verduyn, SC; Vos, MA; Wellens, HJ; Winckels, SK1
Aitken, S; De Jonckheere, B; McCaig, DJ1
Kamijo, T; Kido, H; Miwa, A; Nakamura, F; Sugimoto, T; Tomaru, T; Uchida, Y1
Colatsky, TJ; Harvey, C; Kitzen, JM; McCallum, JD; Morin, ME; Oshiro, GT1
Hamilton, TC; Longman, SD1
Bhattacharjee, S; Kraft, P; Li, X; Lundeen, SG; Qiu, Y; Sui, Z; Woods, M; Zhang, X1

Reviews

2 review(s) available for cromakalim and Disease Models, Animal

ArticleYear
Protective effects of ATP-sensitive potassium-channel openers in experimental myocardial ischemia.
    Journal of cardiovascular pharmacology, 1994, Volume: 24 Suppl 4

    Topics: Action Potentials; Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Dihydropyridines; Disease Models, Animal; Dogs; Guanidines; Guinea Pigs; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Picolines; Pinacidil; Potassium Channels; Pyrans; Pyrroles; Rats; Vasodilator Agents

1994
Potassium channel activator drugs: mechanism of action, pharmacological properties, and therapeutic potential.
    Medicinal research reviews, 1992, Volume: 12, Issue:2

    Topics: Animals; Antihypertensive Agents; Benzopyrans; Cardiovascular System; Central Nervous System; Clinical Trials as Topic; Cromakalim; Disease Models, Animal; Guanidines; Humans; Muscle, Smooth, Vascular; Muscles; Neurons; Niacinamide; Nicorandil; Pancreas; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents

1992

Other Studies

40 other study(ies) available for cromakalim and Disease Models, Animal

ArticleYear
Smooth muscle ATP-sensitive potassium channels mediate migraine-relevant hypersensitivity in mouse models.
    Cephalalgia : an international journal of headache, 2022, Volume: 42, Issue:2

    Topics: Adenosine Triphosphate; Animals; Cromakalim; Disease Models, Animal; Humans; KATP Channels; Mice; Mice, Knockout; Migraine Disorders; Muscle, Smooth; RNA, Messenger

2022
Effect of ATP-sensitive Potassium Channel Openers on Intraocular Pressure in Ocular Hypertensive Animal Models.
    Investigative ophthalmology & visual science, 2022, 02-01, Volume: 63, Issue:2

    Topics: Animals; Antihypertensive Agents; Cromakalim; Diazoxide; Disease Models, Animal; Eye; Intraocular Pressure; KATP Channels; Mice; Mice, Inbred DBA; Microscopy, Electron, Transmission; Ocular Hypertension; Ophthalmic Solutions

2022
A c-Fos activation map in nitroglycerin/levcromakalim-induced models of migraine.
    The journal of headache and pain, 2022, Sep-30, Volume: 23, Issue:1

    Topics: Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Cromakalim; Disease Models, Animal; Humans; Hyperalgesia; Mice; Migraine Disorders; Nitroglycerin; Pain; Proto-Oncogene Proteins c-fos; Receptors, Calcitonin Gene-Related Peptide

2022
PACAP signaling is not involved in GTN- and levcromakalim-induced hypersensitivity in mouse models of migraine.
    The journal of headache and pain, 2022, Dec-05, Volume: 23, Issue:1

    Topics: Animals; Calcitonin Gene-Related Peptide; Cromakalim; Disease Models, Animal; Drug Hypersensitivity; Mice; Migraine Disorders; Nitroglycerin; Pituitary Adenylate Cyclase-Activating Polypeptide; Signal Transduction; Sumatriptan

2022
Characteristics of electromechanical window in anesthetized rabbit models of short QT and long QT syndromes.
    The Journal of toxicological sciences, 2017, Volume: 42, Issue:5

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Benzopyrans; Biomarkers; Biomarkers, Pharmacological; Cromakalim; Disease Models, Animal; Electrocardiography; Isoflurane; Long QT Syndrome; Phenethylamines; Pinacidil; Quinidine; Rabbits; Risk; Sulfonamides; Systole; Torsades de Pointes; Ventricular Pressure

2017
KATP channel opening accelerates and stabilizes rotors in a swine heart model of ventricular fibrillation.
    Cardiovascular research, 2013, Aug-01, Volume: 99, Issue:3

    Topics: Animals; Cromakalim; Disease Models, Animal; Electrophysiological Phenomena; Humans; In Vitro Techniques; KATP Channels; Models, Cardiovascular; Sus scrofa; Ventricular Fibrillation; Voltage-Sensitive Dye Imaging

2013
The β3 Adrenergic Receptor Agonist BRL37344 Exacerbates Atrial Structural Remodeling Through iNOS Uncoupling in Canine Models of Atrial Fibrillation.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 38, Issue:2

    Topics: Adrenergic beta-3 Receptor Agonists; Animals; Atrial Fibrillation; Atrial Remodeling; Cromakalim; Disease Models, Animal; Dogs; Female; Heart Atria; Nitric Oxide Synthase Type II; Oxidative Stress; Receptors, Adrenergic, beta-3

2016
ATP-sensitive potassium channels contribute to the time-dependent alteration in the pentylenetetrazole-induced seizure threshold in diabetic mice.
    Seizure, 2010, Volume: 19, Issue:1

    Topics: Analysis of Variance; Animals; Blood Glucose; Body Weight; Cromakalim; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Glyburide; Hypoglycemic Agents; KATP Channels; Male; Mice; Parasympatholytics; Pentylenetetrazole; Seizures; Time Factors

2010
Role of different types of potassium channels and peroxisome proliferator-activated receptors γ in the antidepressant-like activity of bis selenide in the mouse tail suspension test.
    Neuroscience letters, 2011, Mar-03, Volume: 490, Issue:3

    Topics: Analysis of Variance; Anilides; Animals; Antidepressive Agents; Behavior, Animal; Cromakalim; Disease Models, Animal; Exploratory Behavior; Freezing Reaction, Cataleptic; Hindlimb Suspension; Male; Mice; Organoselenium Compounds; Potassium Channel Blockers; Potassium Channels; PPAR gamma

2011
Impaired vascular responses of insulin-resistant rats after mild subarachnoid hemorrhage.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:6

    Topics: Acetylcholine; Animals; Cerebrovascular Circulation; Cromakalim; Cyclooxygenase 2; Disease Models, Animal; Insulin Resistance; Nitroprusside; Obesity; Rats; Rats, Zucker; Subarachnoid Hemorrhage; Vasodilation; Vasodilator Agents; Vasospasm, Intracranial

2011
Eicosapentaenoic acid reduces ischemic ventricular fibrillation via altering monophasic action potential in pigs.
    Journal of molecular and cellular cardiology, 2011, Volume: 51, Issue:3

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cromakalim; Disease Models, Animal; Eicosapentaenoic Acid; Fatty Acids; Gene Expression Regulation; Male; Myocardial Ischemia; Parasympatholytics; Potassium Channels, Inwardly Rectifying; Swine; Ventricular Fibrillation

2011
K(ATP) channel openers in the trigeminovascular system.
    Cephalalgia : an international journal of headache, 2012, Volume: 32, Issue:1

    Topics: Animals; ATP-Binding Cassette Transporters; Calcitonin Gene-Related Peptide; Cell Degranulation; Cromakalim; Diazoxide; Disease Models, Animal; Dura Mater; KATP Channels; Male; Mast Cells; Migraine Disorders; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley; Receptors, Drug; Sulfonylurea Receptors; Trigeminal Caudal Nucleus; Trigeminal Ganglion; Vasodilator Agents

2012
Alterations in KATP and KCa channel function in cerebral arteries of insulin-resistant rats.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:6

    Topics: Adenosine Triphosphate; Animals; Bradykinin; Calcium; Cerebral Arteries; Cromakalim; Disease Models, Animal; Dose-Response Relationship, Drug; Fructose; Hyperinsulinism; Hyperlipidemias; Hypertriglyceridemia; In Vitro Techniques; Insulin Resistance; Lipoproteins, HDL; Male; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2002
Effects of ATP-sensitive K+ channel openers and tolterodine on involuntary bladder contractions in a pig model of partial bladder outlet obstruction.
    Neurourology and urodynamics, 2003, Volume: 22, Issue:2

    Topics: Adenosine Triphosphate; Animals; Benzhydryl Compounds; Benzoxazines; Cresols; Cromakalim; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Ion Channel Gating; Muscarinic Antagonists; Muscle Contraction; Oxazines; Parasympatholytics; Phenylpropanolamine; Potassium Channels; Sus scrofa; Tolterodine Tartrate; Urinary Bladder; Urinary Bladder Neck Obstruction; Urodynamics

2003
In vivo evaluation of the potency and bladder-vascular selectivity of the ATP-sensitive potassium channel openers (-)-cromakalim, ZD6169 and WAY-133537 in rats.
    BJU international, 2003, Volume: 91, Issue:3

    Topics: Amides; Animals; Benzophenones; Calcium Channels; Cromakalim; Cyclobutanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Male; Muscarinic Antagonists; Muscle Contraction; Nitriles; Rats; Rats, Sprague-Dawley; Reflex, Abnormal; Urinary Bladder; Urinary Bladder Neck Obstruction; Urinary Bladder, Neurogenic; Vasodilator Agents

2003
Mitochondrial K ATP channel activation is important in the antiarrhythmic and cardioprotective effects of non-hypotensive doses of nicorandil and cromakalim during ischemia/reperfusion: a study in an intact anesthetized rabbit model.
    Pharmacological research, 2003, Volume: 47, Issue:6

    Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Pressure; Cromakalim; Decanoic Acids; Disease Models, Animal; Glutathione; Heart Rate; Hydroxy Acids; Male; Malondialdehyde; Membrane Proteins; Myocardial Infarction; Myocardial Reperfusion Injury; Nicorandil; Oxidative Stress; Potassium Channels; Rabbits; Sarcolemma; Sulfonamides; Superoxide Dismutase; Survival Rate; Thiourea

2003
ATP-dependent K+ channels in renal ischemia reperfusion injury.
    Renal failure, 2003, Volume: 25, Issue:6

    Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Cromakalim; Diazoxide; Disease Models, Animal; Glomerular Filtration Rate; Glyburide; Kidney; Kidney Function Tests; Male; Organ Culture Techniques; Potassium Channels; Probability; Rats; Rats, Sprague-Dawley; Reference Values; Reperfusion Injury; Sensitivity and Specificity

2003
Altered vascular reactivity and KATP channel currents in vascular smooth muscle cells from deoxycorticosterone acetate (DOCA)-salt hypertensive rats.
    Journal of cardiovascular pharmacology, 2004, Volume: 44, Issue:5

    Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Blood Pressure; Canada; Cromakalim; Desoxycorticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Implants; Electrophysiology; Endothelium, Vascular; Glyburide; Hypertension; Male; Membrane Potentials; Muscle, Smooth, Vascular; Nephrectomy; Phenylephrine; Potassium Channels; Potassium Chloride; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasodilation

2004
Role of ATP-sensitive potassium channels in the biphasic effects of morphine on pentylenetetrazole-induced seizure threshold in mice.
    Epilepsy research, 2007, Volume: 75, Issue:1

    Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Blood Glucose; Cromakalim; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Glyburide; Hypoglycemic Agents; Male; Mice; Morphine; Narcotics; Pentylenetetrazole; Potassium Channels; Seizures; Severity of Illness Index

2007
Acute antihypertensive action of Tempol in the spontaneously hypertensive rat.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:6

    Topics: Amitrole; Animals; Antihypertensive Agents; Blood Pressure; Buthionine Sulfoximine; Catalase; Cromakalim; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ganglionic Blockers; Glutathione Peroxidase; Glyburide; Heart Rate; Heme Oxygenase (Decyclizing); Hexamethonium; Hypertension; Infusions, Intravenous; KATP Channels; Large-Conductance Calcium-Activated Potassium Channels; Male; Metalloporphyrins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptides; Potassium Channel Blockers; Rats; Rats, Inbred SHR; Spin Labels; Sympathetic Nervous System; Time Factors

2007
Cromakalim suppresses hypertonic saline-induced renal vasoconstriction in anaesthetized dogs.
    Clinical and experimental pharmacology & physiology, 1995, Volume: 22, Issue:4

    Topics: Animals; Benzopyrans; Cromakalim; Disease Models, Animal; Diuresis; Dogs; Female; Glomerular Filtration Rate; Hematocrit; Male; Potassium Channels; Pyrroles; Renal Circulation; Saline Solution, Hypertonic; Sodium; Vasoconstriction; Vasodilator Agents

1995
Ventricular overdrive pacing-induced preconditioning and no-flow ischemia-induced preconditioning in isolated working rat hearts.
    Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:1

    Topics: Animals; Benzopyrans; Blood Pressure; Cardiac Pacing, Artificial; Coronary Circulation; Cromakalim; Disease Models, Animal; Glyburide; Heart; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Potassium Channels; Pyrroles; Rats; Rats, Wistar; Vasodilator Agents

1995
Analysis of the potassium channel openers celikalim, pinacidil and cromakalim in platelet models of thrombosis.
    Thrombosis research, 1994, Jun-01, Volume: 74, Issue:5

    Topics: Animals; Antihypertensive Agents; Benzopyrans; Blood Coagulation; Cromakalim; Disease Models, Animal; Evaluation Studies as Topic; Guanidines; Humans; Indoles; Male; Molecular Structure; Pinacidil; Platelet Aggregation Inhibitors; Potassium Channels; Pyrroles; Rabbits; Stereoisomerism; Thrombosis

1994
Cromakalim does not protect against skeletal muscle fatigue in an anaesthetized rat model of acute hindlimb ischaemia.
    European journal of pharmacology, 1993, Nov-30, Volume: 250, Issue:1

    Topics: Animals; Benzopyrans; Blood Pressure; Cromakalim; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Heart Rate; Hindlimb; Ischemia; Male; Muscle Contraction; Muscles; Pyrroles; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vasodilator Agents

1993
In vivo bronchodilator action of a novel K+ channel opener, KC 399, in the guinea pig.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:1

    Topics: Administration, Inhalation; Albuterol; Anesthesia; Animals; Antigens; Asthma; Benzopyrans; Bronchoconstriction; Bronchodilator Agents; Consciousness; Cromakalim; Disease Models, Animal; Guinea Pigs; Histamine; Immunization; Injections, Intravenous; Male; Potassium Channels; Pyrroles

1994
Therapeutic potential of potassium channel openers in peripheral vascular disease and asthma.
    Cardiovascular drugs and therapy, 1993, Volume: 7 Suppl 3

    Topics: Animals; Asthma; Benzopyrans; Cromakalim; Cyclopentanes; Disease Models, Animal; Humans; Parasympatholytics; Peripheral Vascular Diseases; Potassium Channels; Pyrroles; Rats

1993
Modulation of GABA transmission by diazoxide and cromakalim in the globus pallidus: implications for the treatment of Parkinson's disease.
    Experimental neurology, 1996, Volume: 139, Issue:1

    Topics: Animals; Antihypertensive Agents; Behavior, Animal; Benzopyrans; Cromakalim; Diazoxide; Disease Models, Animal; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Globus Pallidus; Ion Channel Gating; Locomotion; Male; Parkinson Disease; Potassium Channels; Pyrroles; Rats; Rats, Sprague-Dawley; Reserpine; Time Factors

1996
KATP channel modulators increase survival rate during coronary occlusion-reperfusion in anaesthetized rats.
    European journal of pharmacology, 1997, Apr-11, Volume: 324, Issue:1

    Topics: Action Potentials; Adenosine Triphosphate; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzopyrans; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Cromakalim; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Glyburide; Guanidines; Heart Rate; Male; Myocardial Reperfusion Injury; Pinacidil; Potassium Channels; Pyrroles; Rats; Rats, Sprague-Dawley; Survival Rate; Vasodilator Agents; Ventricular Fibrillation

1997
Beneficial hemodynamic effects of nicorandil in a canine model of acute congestive heart failure: comparison with nitroglycerin and cromakalim.
    Fundamental & clinical pharmacology, 1998, Volume: 12, Issue:3

    Topics: Acute Disease; Animals; Blood Pressure; Coronary Circulation; Cromakalim; Disease Models, Animal; Dogs; Female; Heart; Heart Failure; Heart Rate; Male; Myocardial Contraction; Myocardium; Niacinamide; Nicorandil; Nitroglycerin; Saponins; Vasodilator Agents

1998
Vascular responsiveness in alloxan-induced diabetes-susceptible (ALS) and resistant (ALR) mice.
    The Journal of veterinary medical science, 1998, Volume: 60, Issue:10

    Topics: Alloxan; Animals; Blood Glucose; Cromakalim; Diabetes Mellitus, Experimental; Dinoprost; Disease Models, Animal; Disease Susceptibility; Glycosuria; Male; Mice; Muscle, Smooth, Vascular; Nitroprusside; Norepinephrine; Potassium; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

1998
Pretreatment with a potassium-channel opener before prolonged cardiac storage: an evaluation in an experimental brain death model.
    The Annals of thoracic surgery, 1999, Volume: 67, Issue:6

    Topics: Animals; Brain Death; Coronary Circulation; Creatine Kinase; Cromakalim; Disease Models, Animal; Epinephrine; Evaluation Studies as Topic; Ischemic Preconditioning, Myocardial; Norepinephrine; Organ Preservation; Organ Preservation Solutions; Rabbits; Vasodilator Agents

1999
The role of cromakalim and a nitric oxide synthase blocker in cardiac arrhythmia in the intact baboon model.
    Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Catheterization; Cromakalim; Disease Models, Animal; Electrocardiography; Enzyme Inhibitors; Hemodynamics; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Papio; Propranolol; Time Factors

2000
Renin-angiotensin system blockade improves endothelial dysfunction in hypertension.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:4

    Topics: Acetylcholine; Administration, Oral; Angiotensin Receptor Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Benzimidazoles; Biological Factors; Biphenyl Compounds; Cromakalim; Disease Models, Animal; Drug Therapy, Combination; Enalapril; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Indomethacin; Male; Nitroarginine; Norepinephrine; Potassium Channels; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Tetrazoles

2000
Vasopressin-induced protein kinase C-dependent superoxide generation contributes to atp-sensitive potassium channel but not calcium-sensitive potassium channel function impairment after brain injury.
    Stroke, 2001, Volume: 32, Issue:6

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Arteries; Benzimidazoles; Brain Injuries; Brain Ischemia; Calcitonin Gene-Related Peptide; Cromakalim; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Female; Male; Pia Mater; Potassium Channels; Protein Kinase C; Superoxides; Swine; Vasodilation; Vasopressins; Wounds, Nonpenetrating; Xanthine Oxidase

2001
Hemodynamic effects of levcromakalim in neonatal porcine pulmonary hypertension.
    Biology of the neonate, 2001, Volume: 80, Issue:1

    Topics: Animals; Animals, Newborn; Blood Pressure; Cromakalim; Disease Models, Animal; Glyburide; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Ion Channel Gating; Potassium Channels; Streptococcus agalactiae; Swine; Vascular Resistance; Vasodilator Agents

2001
The JT-area indicates dispersion of repolarization in dogs with atrioventricular block.
    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2002, Volume: 6, Issue:2

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Body Surface Potential Mapping; Cromakalim; Disease Models, Animal; Dogs; Electrocardiography; Electrophysiologic Techniques, Cardiac; Heart Block; Heart Conduction System; Heart Ventricles; Signal Processing, Computer-Assisted; Sulfonamides

2002
Comparison of the effects of cromakalim in trachea isolated from normal and albumin-sensitive guinea-pigs.
    The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:10

    Topics: Acetylcholine; Albumins; Animals; Asthma; Benzopyrans; Bronchodilator Agents; Cromakalim; Disease Models, Animal; Electric Stimulation; Flurbiprofen; Guinea Pigs; Immunization; In Vitro Techniques; Male; Potassium Channels; Pyrroles; Trachea

1992
[The vasospasmolytic effects of nicorandil, cromakalim and pinacidil on 3,4-diaminopyridine-induced phasic contractions in canine coronary arteries as an experimental vasospasm model].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1992, Volume: 100, Issue:4

    Topics: 4-Aminopyridine; Amifampridine; Animals; Benzopyrans; Coronary Vasospasm; Cromakalim; Disease Models, Animal; Dogs; Female; Glyburide; Guanidines; In Vitro Techniques; Ion Channel Gating; Male; Methylene Blue; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents

1992
Potassium channel activators cromakalim and celikalim (WAY-120,491) fail to decrease myocardial infarct size in the anesthetized canine.
    Pharmacology, 1992, Volume: 45, Issue:2

    Topics: Animals; Benzopyrans; Coronary Circulation; Coronary Vessels; Cromakalim; Disease Models, Animal; Dogs; Hemodynamics; Indoles; Myocardial Infarction; Perfusion; Potassium Channels; Pyrroles; Regional Blood Flow

1992
Discovery and structure-activity relationships of a novel series of benzopyran-based K(ATP) openers for urge urinary incontinence.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: Animals; Benzopyrans; Disease Models, Animal; Potassium Channels, Inwardly Rectifying; Rats; Structure-Activity Relationship; Urinary Bladder; Urinary Incontinence, Urge

2009