cromakalim has been researched along with Alloxan Diabetes in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.85) | 18.7374 |
| 1990's | 15 (57.69) | 18.2507 |
| 2000's | 6 (23.08) | 29.6817 |
| 2010's | 4 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamaguchi, S; Kanae, H; Kato, K; Kusakabe, T; Namekata, I; Tanaka, H; Wakasugi, Y | 1 |
| Dehpour, AR; Ebrahimi, F; Ghasemi, M; Gholipour, T; Karimollah, AR; Nezami, BG; Shafaroodi, H | 1 |
| Lawson, K; McKay, NG; Sellers, DJ; Vahabi, B | 1 |
| Omogbai, EK; Owolabi, OJ | 1 |
| Goyal, RK; Kulkarni, JS; Metha, AA; Santani, DD | 1 |
| Kamata, K; Kobayashi, T; Matsumoto, T; Wakabayashi, K; Yoshiyama, S | 1 |
| Asadi, S; Dehpour, AR; Ghasemi, M; Sadeghipour, H | 1 |
| Kam, KL; Pfaffendorf, M; van Zwieten, PA | 1 |
| Kamei, J; Kasuya, Y; Kawashima, N; Misawa, M; Narita, M; Suzuki, T | 1 |
| Mayhan, WG | 1 |
| Das, DK; Engelman, DT; Engelman, RM; Tosaki, A | 1 |
| Das, DK; Engelman, RM; Tosaki, A | 1 |
| Anthony, DM; Buckett, WR; Dickinson, K; Jones, RB; Kaul, CL; Marita, AR | 1 |
| Das, DK; Tosaki, A | 1 |
| Higuchi, M; Kayo, S; Miyagi, K; Sakanashi, M | 1 |
| Bouchard, JF; Dumont, EC; Lamontagne, D | 2 |
| Crijns, FR; Struijker Boudier, HA; Wolffenbuttel, BH | 1 |
| French, RJ; Light, PE; Shimoni, Y | 1 |
| Abe, A; Kawazoe, C; Kondo, Y; Sato, K | 1 |
| Kamata, K; Kirisawa, H; Ohuchi, K | 1 |
| Sharma, A; Singh, M; Sood, V | 1 |
| Brown, RA; Petrovski, P; Ren, J; Savage, AO | 1 |
| Kamata, K; Kasuya, Y; Miyata, N; Otomo, S; Tsuchida, K; Yamaura, H | 1 |
| Honoré, E; Lazdunski, M | 1 |
| Kamata, K; Kasuya, Y; Miyata, N | 1 |
26 other study(ies) available for cromakalim and Alloxan Diabetes
| Article | Year |
|---|---|
Pathological prolongation of action potential duration as a cause of the reduced alpha-adrenoceptor-mediated negative inotropy in streptozotocin-induced diabetic mice myocardium.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cromakalim; Depression, Chemical; Diabetes Mellitus, Experimental; Male; Mice, Inbred Strains; Myocardial Contraction; Phenylephrine; Receptors, Adrenergic, alpha; Streptozocin | 2017 |
ATP-sensitive potassium channels contribute to the time-dependent alteration in the pentylenetetrazole-induced seizure threshold in diabetic mice.
Topics: Analysis of Variance; Animals; Blood Glucose; Body Weight; Cromakalim; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Glyburide; Hypoglycemic Agents; KATP Channels; Male; Mice; Parasympatholytics; Pentylenetetrazole; Seizures; Time Factors | 2010 |
Phasic activity of urinary bladder smooth muscle in the streptozotocin-induced diabetic rat: effect of potassium channel modulators.
Topics: Animals; Benzimidazoles; Cromakalim; Diabetes Mellitus, Experimental; In Vitro Techniques; Ion Channel Gating; Male; Muscle, Smooth; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Urinary Bladder | 2011 |
Evaluation of the potassium channel activator levcromakalim (BRL38227) on the lipid profile, electrolytes and blood glucose levels of streptozotocin-diabetic rats.
Topics: Animals; Blood Glucose; Cromakalim; Diabetes Mellitus, Experimental; Electrolytes; Female; Lipids; Male; Potassium Channels; Rats; Rats, Wistar; Streptozocin | 2013 |
Effects of chronic treatment with cromakalim and glibenclamide in alloxan-induced diabetic rats.
Topics: Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Cromakalim; Diabetes Mellitus, Experimental; Drug Interactions; Female; Glyburide; Heart Rate; Hypertension; Hypoglycemic Agents; Rats; Rats, Wistar | 2002 |
Effect of chronic insulin on cromakalim-induced relaxation in established streptozotocin-diabetic rat basilar artery.
Topics: Animals; Basilar Artery; Cromakalim; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Administration Schedule; Insulin; Male; Rats; Rats, Wistar; Vasodilation | 2004 |
Time-dependent alteration in cromakalim-induced relaxation of corpus cavernosum from streptozocin-induced diabetic rats.
Topics: Animals; Cromakalim; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glyburide; In Vitro Techniques; Male; Muscle Relaxation; Penis; Potassium Channels; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Streptozocin; Time Factors | 2007 |
Drug-induced endothelium-dependent and -independent relaxations in isolated resistance vessels taken from simultaneously hypertensive and streptozotocin-diabetic rats.
Topics: Animals; Benzopyrans; Bradykinin; Calcium; Cromakalim; Diabetes Mellitus, Experimental; Endothelium, Vascular; Glyburide; Histamine; Hypertension; Male; Mesenteric Arteries; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitroprusside; Potassium Channels; Potassium Chloride; Pyrroles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Streptozocin; Vascular Resistance; Vasodilation; Vasodilator Agents | 1994 |
Reduction in ATP-sensitive potassium channel-mediated antinociception in diabetic mice.
Topics: Adenosine Triphosphate; Analgesics; Animals; Benzopyrans; Blood Glucose; Cromakalim; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glyburide; Male; Mice; Mice, Inbred ICR; Morphine; Pain Measurement; Potassium Channels; Pyrroles; Receptors, Opioid, mu; Tetraethylammonium Compounds | 1994 |
Effect of diabetes mellitus on response of the basilar artery to activation of ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Basilar Artery; Benzopyrans; Blood Pressure; Cromakalim; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Male; Nitroglycerin; Picolines; Potassium Channels; Pyrans; Pyrroles; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1994 |
Diabetes and ATP-sensitive potassium channel openers and blockers in isolated ischemic/reperfused hearts.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzopyrans; Cations; Cromakalim; Diabetes Mellitus, Experimental; Glyburide; Heart Function Tests; Hypoglycemic Agents; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Potassium Channel Blockers; Potassium Channels; Pyrroles; Rats; Rats, Sprague-Dawley; Streptozocin | 1995 |
Effects of cromakalim and glibenclamide in ischemic and reperfused hearts.
Topics: Animals; Anti-Arrhythmia Agents; Benzopyrans; Cromakalim; Diabetes Mellitus, Experimental; Glyburide; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Pyrroles; Rats; Rats, Sprague-Dawley | 1996 |
Evaluation of BTS 67 582, a novel antidiabetic agent, in normal and diabetic rats.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Blood Glucose; Brain; Cromakalim; Diabetes Mellitus, Experimental; Diazoxide; Glucose; Glyburide; Guanidines; Hypoglycemic Agents; In Vitro Techniques; Insulin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Channel Blockers; Pyrroles; Rats; Rats, Wistar; Tumor Cells, Cultured | 1997 |
Extracellular Mg++ manipulation prevents the proarrhythmic activity of cromakalim in ischemic/reperfused diabetic hearts.
Topics: Animals; Arrhythmias, Cardiac; Benzopyrans; Calcium; Cromakalim; Diabetes Mellitus, Experimental; Heart; Magnesium; Male; Myocardial Ischemia; Myocardial Reperfusion; Potassium Channels; Pyrroles; Rats; Rats, Sprague-Dawley; Sodium; Streptozocin | 1997 |
Acceleration of stiffness in underperfused diabetic rat hearts by glyburide, a KATP channel blocker, and its prevention by levcromakalim and insulin.
Topics: Animals; Anti-Arrhythmia Agents; Coronary Circulation; Cromakalim; Diabetes Mellitus, Experimental; Glyburide; Hypoglycemic Agents; Insulin; Male; Myocardial Contraction; Norepinephrine; Perfusion; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley | 1997 |
[Decrease of vascular response to iloprost in diabetic rats].
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Aorta, Thoracic; Colforsin; Coronary Vessels; Cromakalim; Diabetes Mellitus, Experimental; Iloprost; Potassium Channels; Rats; Rats, Sprague-Dawley; Streptozocin; Vascular Resistance; Vasodilation; Vasodilator Agents | 1997 |
Arteriolar reactivity in conscious diabetic rats: influence of aminoguanidine treatment.
Topics: Acetylcholine; Angiotensin II; Animals; Arterioles; Blood Glucose; Blood Pressure; Consciousness; Cromakalim; Diabetes Mellitus, Experimental; Endothelium, Vascular; Enzyme Inhibitors; Glycated Hemoglobin; Guanidines; Male; Microcirculation; Muscle, Skeletal; Norepinephrine; Potassium Channels; Rats; Rats, Wistar; Vasoconstrictor Agents; Vasodilator Agents | 1998 |
Altered ATP sensitivity of ATP-dependent K+ channels in diabetic rat hearts.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Cells, Cultured; Cromakalim; Diabetes Mellitus, Experimental; Electric Conductivity; Heart; Heart Ventricles; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Reference Values | 1998 |
Vascular responsiveness in alloxan-induced diabetes-susceptible (ALS) and resistant (ALR) mice.
Topics: Alloxan; Animals; Blood Glucose; Cromakalim; Diabetes Mellitus, Experimental; Dinoprost; Disease Models, Animal; Disease Susceptibility; Glycosuria; Male; Mice; Muscle, Smooth, Vascular; Nitroprusside; Norepinephrine; Potassium; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 1998 |
Modification of vasodilator response in streptozotocin-induced diabetic rat.
Topics: Adenylyl Cyclases; Animals; Aorta, Thoracic; Cromakalim; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Interactions; Heart; Iloprost; Male; Mesenteric Arteries; Phenylephrine; Potassium Channels; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 1999 |
Altered endothelium-dependent and -independent hyperpolarization and endothelium-dependent relaxation in carotid arteries isolated from streptozotocin-induced diabetic rats.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Animals; Carotid Arteries; Cromakalim; Diabetes Mellitus, Experimental; Endothelium, Vascular; In Vitro Techniques; Isometric Contraction; Male; Membrane Potentials; Microelectrodes; Muscle Relaxation; Muscle, Smooth, Vascular; Pertussis Toxin; Rats; Rats, Wistar; Thromboxane B2; Virulence Factors, Bordetella | 2000 |
Role of KATP channels in reduced antinociceptive effect of morphine in streptozotocin-induced diabetic mice.
Topics: Adenosine Triphosphate; Analgesics; Animals; Cromakalim; Diabetes Mellitus, Experimental; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Morphine; Potassium Channels; Spleen | 2000 |
Influence of ATP-sensitive K+ channel modulation on the mechanical properties of diabetic myocardium.
Topics: Adenosine Triphosphate; Animals; Biomechanical Phenomena; Blood Glucose; Cromakalim; Depression, Chemical; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Glyburide; Male; Myocardial Contraction; Pinacidil; Potassium Channels; Rats; Rats, Wistar; Vasodilator Agents | 2001 |
Changes in responsiveness of the aorta to vasorelaxant agents in genetically diabetic rats: a study in WBN/Kob rats.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Colforsin; Cromakalim; Diabetes Mellitus, Experimental; Endothelium, Vascular; Isoproterenol; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Vasodilator Agents | 1992 |
Hormone-regulated K+ channels in follicle-enclosed oocytes are activated by vasorelaxing K+ channel openers and blocked by antidiabetic sulfonylureas.
Topics: Animals; Benzopyrans; Cromakalim; Cyclic AMP; Diabetes Mellitus, Experimental; Female; Hormones; Oocytes; Potassium Channels; Pyrroles; Sulfonylurea Compounds; Vasodilator Agents; Xenopus laevis | 1991 |
Functional changes in potassium channels in aortas from rats with streptozotocin-induced diabetes.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Blood Glucose; Cromakalim; Diabetes Mellitus, Experimental; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Niacinamide; Nicorandil; Norepinephrine; Parasympatholytics; Potassium Channels; Pyrroles; Rats; Rats, Inbred Strains | 1989 |