crizotinib has been researched along with Drug-Hypersensitivity* in 2 studies
2 other study(ies) available for crizotinib and Drug-Hypersensitivity
Article | Year |
---|---|
Successful Oral Desensitization in a Patient With Hypersensitivity Reaction to Crizotinib.
Topics: Aged; Crizotinib; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Protein Kinase Inhibitors; Pyrazoles; Pyridines | 2015 |
Successful desensitization of two patients with ALK-positive lung cancer and hypersensitivity to crizotinib.
The tyrosine kinase inhibitor crizotinib is an effective therapy for patients with cancers harboring rearrangements of the anaplastic lymphoma kinase (ALK) gene. Here, we describe two patients with advanced ALK-positive lung cancer who developed hypersensitivity to crizotinib, requiring temporary discontinuation of the drug. Both patients were treated with a rapid oral desensitization protocol allowing them to resume crizotinib without further signs or symptoms of hypersensitivity. Topics: Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Crizotinib; Drug Hypersensitivity; Female; Humans; Lung Neoplasms; Middle Aged; Pyrazoles; Pyridines | 2014 |