crizotinib and Drug-Hypersensitivity

crizotinib has been researched along with Drug-Hypersensitivity* in 2 studies

Other Studies

2 other study(ies) available for crizotinib and Drug-Hypersensitivity

ArticleYear
Successful Oral Desensitization in a Patient With Hypersensitivity Reaction to Crizotinib.
    Journal of investigational allergology & clinical immunology, 2015, Volume: 25, Issue:4

    Topics: Aged; Crizotinib; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Protein Kinase Inhibitors; Pyrazoles; Pyridines

2015
Successful desensitization of two patients with ALK-positive lung cancer and hypersensitivity to crizotinib.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2014, Volume: 9, Issue:11

    The tyrosine kinase inhibitor crizotinib is an effective therapy for patients with cancers harboring rearrangements of the anaplastic lymphoma kinase (ALK) gene. Here, we describe two patients with advanced ALK-positive lung cancer who developed hypersensitivity to crizotinib, requiring temporary discontinuation of the drug. Both patients were treated with a rapid oral desensitization protocol allowing them to resume crizotinib without further signs or symptoms of hypersensitivity.

    Topics: Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Crizotinib; Drug Hypersensitivity; Female; Humans; Lung Neoplasms; Middle Aged; Pyrazoles; Pyridines

2014