cremophor el has been researched along with Neoplasms in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (16.67) | 18.2507 |
| 2000's | 12 (50.00) | 29.6817 |
| 2010's | 8 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Najjar, BY; Alhnan, MA; El Nemr, S; Elhissi, AMA; Omer, HK | 1 |
| Chowdhury, MR; Goto, M; Kamiya, N; Moniruzzaman, M; Moshikur, RM; Tahara, Y; Wakabayashi, R | 1 |
| Aserin, A; Ezrahi, S; Garti, N | 1 |
| Chen, JS; Chen, PM; Chu, Z; Figg, WD; Gardner, ER; Liau, CT; Lin, YC; Sparreboom, A; Wang, HM; Yang, MH | 1 |
| Danhier, F; Feron, O; Jérôme, C; Lecouturier, N; Marchand-Brynaert, J; Préat, V; Vroman, B | 1 |
| Diao, YY; Fang, QL; Gao, JQ; Han, M; He, CX; He, QJ; Hu, YZ; Liang, WQ; Xu, DH; Yang, B; Yang, XC | 1 |
| Bathula, SR; Conwell, C; Huang, L; Liu, F; Liu, Y; Park, JY; Zhang, Y | 1 |
| Bushman, J; Garbuzenko, OB; Gounder, MK; Kohn, J; Minko, T; Sheihet, L | 1 |
| Chen, X; Liu, X; Scott, H; Sun, J; Wang, S; Zhang, Q; Zhang, X | 1 |
| García-Díaz, M; Hamblin, MR; Kawakubo, M; Mora, M; Mroz, P; Nonell, S; Sagristà, ML | 1 |
| Balasubramanian, T; Bocian, DF; Diers, JR; Hamblin, MR; Holten, D; Huang, YY; Lindsey, JS; Luo, D; Yang, E | 1 |
| Beijnen, JH; Mathôt, RA; Schellens, JH; van den Bongard, HJ; van Tellingen, O | 1 |
| Ellis, AG; Loi, S; Michael, M; Millward, MJ; Rischin, D; Stokes, KH; Webster, LK; Yuen, K | 1 |
| Pishko, MV; Zahr, AS | 1 |
| Bergh, J; Brodin, O; Csoka, K; Fridborg, H; Glimelius, B; Hagberg, H; Jonsson, B; Kreuger, A; Nygren, P; Tholander, B | 1 |
| Anderson, N; Lokich, J | 1 |
| Brouwer, E; de Vos, AI; Gianni, L; Locatelli, A; Loos, WJ; Nooter, K; Sparreboom, A; Stoter, G; van der Burg, ME; Verweij, J; Viganò, L | 1 |
| Bishop, JF; Linahan, BM; Linsenmeyer, ME; Millward, MJ; Olver, IN; Rischin, D; Stokes, KH; Toner, GC; Webster, LK; Woodcock, DM | 1 |
| Brouwer, E; Gianni, L; Loos, WJ; Mross, K; Sparreboom, A; van Zuylen, L; Verweij, J | 1 |
| Sparreboom, A; van Zuylen, L; Verweij, J | 1 |
| Gianni, L; Grasselli, G; Locatelli, A; Vigano, L | 1 |
| Bardelmeijer, HA; Beijnen, JH; Koopman, FJ; Malingré, MM; Ouwehand, M; Rosing, H; Schellens, JH; Schot, ME; Ten Bokkel Huinink, WW; Van Tellingen, O | 1 |
| Behringer, D; Gelderblom, H; Mielke, S; Mross, K; Sparreboom, A; ten Tije, AJ; van Zomeren, DM; Verweij, J | 1 |
| Briasoulis, E; Haidou, C; Karavasilis, V; Pavlidis, N; Piperidou, C; Tzamakou, E | 1 |
3 review(s) available for cremophor el and Neoplasms
| Article | Year |
|---|---|
Basic principles of drug delivery systems - the case of paclitaxel.
Topics: Antineoplastic Agents, Phytogenic; Biological Availability; Biological Transport; Drug Delivery Systems; Drug Stability; Emulsions; Glycerol; Humans; Microtubules; Mitosis; Nanostructures; Neoplasms; Paclitaxel; Solubility; Solvents; Tumor Cells, Cultured | 2019 |
Role of formulation vehicles in taxane pharmacology.
Topics: Animals; Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chemistry, Pharmaceutical; Cyclosporine; Drug Hypersensitivity; Drug Resistance, Multiple; Glycerol; Humans; Micelles; Neoplasms; Nervous System Diseases; Paclitaxel; Polysorbates; Surface-Active Agents | 2001 |
Drug interactions of paclitaxel and docetaxel and their relevance for the design of combination therapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Chemistry, Pharmaceutical; Cisplatin; Docetaxel; Drug Administration Schedule; Drug Interactions; Glycerol; Humans; Neoplasms; Paclitaxel; Pharmaceutical Vehicles; Radiotherapy, Adjuvant; Taxoids; Vinca Alkaloids | 2001 |
6 trial(s) available for cremophor el and Neoplasms
| Article | Year |
|---|---|
Oral bioavailability of a novel paclitaxel formulation (Genetaxyl) administered with cyclosporin A in cancer patients.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Phytogenic; Area Under Curve; Biological Availability; Cyclosporine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glycerol; Humans; Immunosuppressive Agents; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Paclitaxel | 2008 |
A randomized cross-over trial to determine the effect of Cremophor EL on the pharmacodynamics and pharmacokinetics of carboplatin chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Area Under Curve; Carboplatin; Cross-Over Studies; Female; Glycerol; Humans; Male; Metabolic Clearance Rate; Middle Aged; Neoplasms; Surface-Active Agents | 2004 |
Phase I trial of cremophor EL with bolus doxorubicin.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Cross-Over Studies; Doxorubicin; Female; Glycerol; Humans; Male; Middle Aged; Neoplasms; Pharmaceutical Vehicles | 1998 |
Inter-relationships of paclitaxel disposition, infusion duration and cremophor EL kinetics in cancer patients.
Topics: Antineoplastic Agents, Phytogenic; Glycerol; Humans; Infusions, Intravenous; Neoplasms; Paclitaxel; Surface-Active Agents | 2000 |
The co-solvent Cremophor EL limits absorption of orally administered paclitaxel in cancer patients.
Topics: Administration, Oral; Antineoplastic Agents, Phytogenic; Area Under Curve; Cyclosporine; Drug Combinations; Feces; Glycerol; Humans; Intestinal Absorption; Neoplasms; Paclitaxel; Pharmaceutical Vehicles; Polysorbates; Solvents | 2001 |
Comparative pharmacokinetics of unbound paclitaxel during 1- and 3-hour infusions.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Area Under Curve; Drug Administration Schedule; Female; Glycerol; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Neutropenia; Paclitaxel; Surface-Active Agents; Thrombocytopenia; Time Factors | 2002 |
15 other study(ies) available for cremophor el and Neoplasms
| Article | Year |
|---|---|
Studies of the precipitation pattern of paclitaxel in intravenous infusions and rat plasma using laser nephelometry.
Topics: Albumins; Animals; Antineoplastic Agents, Phytogenic; Chemistry, Pharmaceutical; Drug Carriers; Glycerol; Infusions, Intravenous; Lasers; Neoplasms; Nephelometry and Turbidimetry; Paclitaxel; Plasma; Rats; Rats, Wistar | 2018 |
Ionic-Liquid-Based Paclitaxel Preparation: A New Potential Formulation for Cancer Treatment.
Topics: Antineoplastic Agents, Phytogenic; Drug Compounding; Drug Delivery Systems; Drug Hypersensitivity; Excipients; Glycerol; HeLa Cells; Humans; Ionic Liquids; Neoplasms; Paclitaxel; Solubility | 2018 |
Paclitaxel-loaded PEGylated PLGA-based nanoparticles: in vitro and in vivo evaluation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Survival; Drug Carriers; Drug Evaluation, Preclinical; Ethylene Oxide; Excipients; Flow Cytometry; Glycerol; HeLa Cells; Humans; Lactic Acid; Lactones; Male; Mice; Mice, Inbred Strains; Nanoparticles; Neoplasms; Paclitaxel; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface-Active Agents; Survival Analysis | 2009 |
A novel camptothecin derivative incorporated in nano-carrier induced distinguished improvement in solubility, stability and anti-tumor activity both in vitro and in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Stability; Emulsifying Agents; Emulsions; Fluorescent Dyes; Glycerol; Hemolysis; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Male; Mice; Microscopy, Fluorescence; Nanostructures; Neoplasms; Oxazines; Particle Size; Rabbits; Solubility; Xenograft Model Antitumor Assays | 2009 |
Targeted cancer therapy with novel high drug-loading nanocrystals.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Carrier Proteins; Chemistry, Pharmaceutical; Drug Delivery Systems; Excipients; Female; Folate Receptors, GPI-Anchored; Glycerol; Hemolysis; Humans; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron, Transmission; Nanoparticles; Neoplasm Transplantation; Neoplasms; Paclitaxel; Poloxamer; Receptors, Cell Surface; Surface-Active Agents | 2010 |
Paclitaxel in tyrosine-derived nanospheres as a potential anti-cancer agent: in vivo evaluation of toxicity and efficacy in comparison with paclitaxel in Cremophor.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Carriers; Female; Glycerol; Humans; Maximum Tolerated Dose; Mice; Mice, Nude; Nanospheres; Neoplasms; Paclitaxel; Pharmaceutical Vehicles; Tyrosine; Xenograft Model Antitumor Assays | 2012 |
Pharmacokinetics, tissue distribution and anti-tumour efficacy of paclitaxel delivered by polyvinylpyrrolidone solid dispersion.
Topics: Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Cell Line, Tumor; Drug Carriers; Female; Glycerol; Humans; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Mice, Nude; Neoplasms; Paclitaxel; Phytotherapy; Plant Preparations; Povidone; Rats; Rats, Sprague-Dawley; Taxus; Tissue Distribution | 2012 |
Cellular and vascular effects of the photodynamic agent temocene are modulated by the delivery vehicle.
Topics: Animals; Cell Line, Tumor; Drug Carriers; Glycerol; Light; Liposomes; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Micelles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Porphyrins; Tumor Burden | 2012 |
Stable synthetic bacteriochlorins for photodynamic therapy: role of dicyano peripheral groups, central metal substitution (2H, Zn, Pd), and Cremophor EL delivery.
Topics: Animals; Coordination Complexes; Glycerol; HeLa Cells; Humans; Neoplasms; Palladium; Pharmaceutical Vehicles; Photochemotherapy; Photosensitizing Agents; Porphyrins; Zinc | 2012 |
A population analysis of the pharmacokinetics of Cremophor EL using nonlinear mixed-effect modelling.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Carboplatin; Female; Glycerol; Humans; Infusions, Intravenous; Male; Middle Aged; Models, Biological; Neoplasms; Paclitaxel; Pharmaceutical Vehicles; Surface-Active Agents | 2002 |
Encapsulation of paclitaxel in macromolecular nanoshells.
Topics: Cell Cycle; Cell Line, Tumor; Cytoskeleton; Drug Delivery Systems; Glycerol; Humans; Macromolecular Substances; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nanoparticles; Neoplasms; Paclitaxel; Polymers; Solvents | 2007 |
The cytotoxic activity of Taxol in primary cultures of tumour cells from patients is partly mediated by Cremophor EL.
Topics: Antineoplastic Agents; Drug Screening Assays, Antitumor; Drug Synergism; Fluorometry; Glycerol; Humans; Kinetics; Neoplasms; Paclitaxel; Solvents; Tumor Cells, Cultured | 1995 |
Paclitaxel hypersensitivity reactions: a role for docetaxel substitution.
Topics: Aged; Antineoplastic Agents, Phytogenic; Docetaxel; Drug Hypersensitivity; Female; Glycerol; Humans; Male; Middle Aged; Neoplasms; Paclitaxel; Taxoids | 1998 |
Disposition of Cremophor EL in humans limits the potential for modulation of the multidrug resistance phenotype in vivo.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Body Fluid Compartments; Cisplatin; Clinical Trials, Phase I as Topic; Doxorubicin; Drug Resistance, Multiple; Female; Glycerol; Humans; Infusions, Intravenous; Middle Aged; Neoplasms; Paclitaxel; Phenotype; Surface-Active Agents; Tissue Distribution | 1998 |
Pharmacodynamics of non-break weekly paclitaxel (Taxol) and pharmacokinetics of Cremophor-EL vehicle: results of a dose-escalation study.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Area Under Curve; Dose-Response Relationship, Drug; Female; Glycerol; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Neutropenia; Paclitaxel; Pharmaceutical Vehicles; Surface-Active Agents | 2002 |