cremophor el has been researched along with Allergy, Drug in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (33.33) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Arcangeli, M; Baldari, B; D'Errico, S; Fineschi, V; Frati, P; Santurro, A | 1 |
| Chowdhury, MR; Goto, M; Kamiya, N; Moniruzzaman, M; Moshikur, RM; Tahara, Y; Wakabayashi, R | 2 |
| Cho, NJ; Fülöp, T; Jackman, JA; Mészáros, T; Szebeni, J; Urbanics, R | 1 |
| He, L; Wang, GL; Zhang, Q | 1 |
| Descotes, J; Evreux, JC; Laschi-Locquerie, A; Tachon, P | 1 |
| Descotes, J; Evreux, JC; Guillot, JP; Laschi-Loquerie, A; Tachon, P | 1 |
| Clarke, RS | 1 |
| Dorr, RT | 1 |
| Alving, CR; Muggia, FM; Szebeni, J | 1 |
| Anderson, N; Lokich, J | 1 |
| Alving, CR; Barenholz, Y; Danino, D; Priev, A; Savay, S; Szebeni, J; Talmon, Y | 1 |
| Sparreboom, A; van Zuylen, L; Verweij, J | 1 |
| Ennis, M; Gerland, W; Lorenz, W | 1 |
| Burckart, GJ; Griffith, BP; Hardesty, RJ; Howrie, DL; Ptachcinski, RJ; Rosenthal, JT; Venkataramanan, R | 1 |
2 review(s) available for cremophor el and Allergy, Drug
| Article | Year |
|---|---|
Pharmacology and toxicology of Cremophor EL diluent.
Topics: Animals; Drug Hypersensitivity; Glycerol; Humans; Paclitaxel; Pharmaceutical Vehicles; Solvents; Surface-Active Agents | 1994 |
Role of formulation vehicles in taxane pharmacology.
Topics: Animals; Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chemistry, Pharmaceutical; Cyclosporine; Drug Hypersensitivity; Drug Resistance, Multiple; Glycerol; Humans; Micelles; Neoplasms; Nervous System Diseases; Paclitaxel; Polysorbates; Surface-Active Agents | 2001 |
13 other study(ies) available for cremophor el and Allergy, Drug
| Article | Year |
|---|---|
Mast cells activation and high blood tryptase levels due to paclitaxel administration. Is Cremophor EL the culprit?: A case report.
Topics: Aged; Drug Hypersensitivity; Glycerol; Humans; Male; Mast Cells; Paclitaxel; Tryptases; Urologic Neoplasms | 2020 |
Ionic-Liquid-Based Paclitaxel Preparation: A New Potential Formulation for Cancer Treatment.
Topics: Antineoplastic Agents, Phytogenic; Drug Compounding; Drug Delivery Systems; Drug Hypersensitivity; Excipients; Glycerol; HeLa Cells; Humans; Ionic Liquids; Neoplasms; Paclitaxel; Solubility | 2018 |
In vivo biocompatibility, pharmacokinetics, antitumor efficacy, and hypersensitivity evaluation of ionic liquid-mediated paclitaxel formulations.
Topics: Administration, Intravenous; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Delivery Systems; Drug Hypersensitivity; Female; Glycerol; Ionic Liquids; Melanoma; Mice, Inbred C57BL; Paclitaxel; Skin Neoplasms | 2019 |
Comparison of complement activation-related pseudoallergy in miniature and domestic pigs: foundation of a validatable immune toxicity model.
Topics: Amphotericin B; Animals; Complement Activation; Disease Models, Animal; Doxorubicin; Drug Hypersensitivity; Glycerol; Humans; Liposomes; Nanomedicine; Nanoparticles; Polyethylene Glycols; Swine; Swine, Miniature; Zymosan | 2016 |
An alternative paclitaxel microemulsion formulation: hypersensitivity evaluation and pharmacokinetic profile.
Topics: Animals; Antineoplastic Agents, Phytogenic; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Hypersensitivity; Emulsions; Female; Glycerol; Guinea Pigs; Male; Paclitaxel | 2003 |
Adjuvancy of Cremophor Elo in rodents.
Topics: Adjuvants, Immunologic; Animals; Drug Hypersensitivity; Female; Glycerol; Guinea Pigs; Hypersensitivity, Delayed; Male; Mice; Pregnanediones; Serum Albumin, Bovine | 1983 |
Assessment of the allergenic potential of althesin and its constituents.
Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Drug Hypersensitivity; Female; Glycerol; Guinea Pigs; Intradermal Tests; Male; Pregnanediones | 1983 |
Epidemiology of adverse reactions in anaesthesia in the United Kingdom.
Topics: Adjuvants, Anesthesia; Anesthetics; Drug Hypersensitivity; Glycerol; Humans; Neuromuscular Blocking Agents; United Kingdom | 1982 |
Complement activation by Cremophor EL as a possible contributor to hypersensitivity to paclitaxel: an in vitro study.
Topics: Antineoplastic Agents, Phytogenic; Complement Activation; Drug Hypersensitivity; Enzyme-Linked Immunosorbent Assay; Glycerol; Humans; In Vitro Techniques; Paclitaxel; Pharmaceutical Vehicles | 1998 |
Paclitaxel hypersensitivity reactions: a role for docetaxel substitution.
Topics: Aged; Antineoplastic Agents, Phytogenic; Docetaxel; Drug Hypersensitivity; Female; Glycerol; Humans; Male; Middle Aged; Neoplasms; Paclitaxel; Taxoids | 1998 |
Formation of complement-activating particles in aqueous solutions of Taxol: possible role in hypersensitivity reactions.
Topics: Antineoplastic Agents, Phytogenic; Complement Activation; Complement Membrane Attack Complex; Drug Hypersensitivity; Glycerol; Humans; Immunoglobulins, Intravenous; Micelles; Paclitaxel; Solutions | 2001 |
Modulation of histamine release from rat peritoneal mast cells by non-cytotoxic concentrations of the detergents Cremophor El (oxethylated castor oil) and Triton X100. A possible explanation for unexpected adverse drug reactions?
Topics: Animals; Calcimycin; Drug Hypersensitivity; Female; Glycerol; Histamine Release; Mast Cells; Octoxynol; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Polyethylene Glycols; Rats; Rats, Inbred Strains | 1986 |
Anaphylactoid reactions associated with parenteral cyclosporine use: possible role of Cremophor EL.
Topics: Adult; Anaphylaxis; Cyclosporins; Drug Hypersensitivity; Excipients; Female; Glycerol; Humans; Male | 1985 |