Page last updated: 2024-10-17

creatine and Reperfusion Injury

creatine has been researched along with Reperfusion Injury in 38 studies

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the effect of creatine supplementation in the diet of rats subjected to ischemia and reperfusion of hind limbs."8.02Effects of dietary creatine supplementation on kidney and striated skeletal muscles of rats submitted to ischemia and reperfusion of hind limbs. ( Francisco Neto, A; Moreira Neto, AA; Moreira, FMDR; Rigopoulos, L; Soufen, MA; Tsunemi, D, 2021)
"Serum metabonomic profiles of the model of focal cerebral ischemia reperfusion is established with the suture-occluded method by Longa to study the effect of ginsenosides."7.96[Effect of ginsenosides on serous metabonomic profiles in cerebral ischemia-reperfusion rats based on ~1H-NMR]. ( Cao, DM; Guan, QX; Liu, YL; Wang, SM, 2020)
"Creatine (Cr) is a dietary supplement that presents beneficial effects in experimental models of heart and brain ischemia and reperfusion (I/R) injury."7.83Creatine supplementation attenuates pulmonary and systemic effects of lung ischemia and reperfusion injury. ( Albertini, R; Almeida, FM; Carvalho, PT; Castro-Faria-Neto, HC; Damaceno-Rodrigues, NR; Dolhnikoff, M; Lopes, FD; Martins, MA; Oliveira-Junior, MC; Pazetti, R; Petroni, RC; Soriano, FG; Soto, SF; Souza, RA; Vieira, RP, 2016)
"These results demonstrate that pre-treatment with paricalcitol has a renoprotective effect in ischemic AKI, possibly by suppressing TLR4-NF-κB mediated inflammation."7.80Renoprotective effect of paricalcitol via a modulation of the TLR4-NF-κB pathway in ischemia/reperfusion-induced acute kidney injury. ( Cho, E; Cho, WY; Jo, SK; Kim, HK; Kim, MG; Kim, SC; Ko, YS; Lee, HY; Lee, JW, 2014)
"To investigate the effects of dietary creatine supplementation alone and in combination with exercise on basal cardiac function, susceptibility to ischaemia/reperfusion injury and mitochondrial oxidative function."7.78The effect of creatine supplementation on myocardial function, mitochondrial respiration and susceptibility to ischaemia/reperfusion injury in sedentary and exercised rats. ( Du Toit, EF; Huisamen, B; Lochner, A; Webster, I, 2012)
"The authors compared temporal profiles of N-acetylaspartate (NAA) and the NAA/total creatine ratio with neuronal and astrocytic densities and with tissue atrophy in the hippocampal CA1 sector of gerbils after 5-minute bilateral forebrain ischemia and subsequent reperfusion for up to 6 months."7.72N-acetylaspartate to total creatine ratio in the hippocampal CA1 sector after transient cerebral ischemia in gerbils: influence of neuronal elements, reactive gliosis, and tissue atrophy. ( Konaka, K; Li, JY; Matsumoto, M; Sakoda, S; Ueda, H; Yanagihara, T, 2003)
"Fondaparinux is a synthetic pentasaccharide that selectively inhibits factor Xa (FXa) in the coagulation cascade."5.33The synthetic pentasaccharide fondaparinux reduces coagulation, inflammation and neutrophil accumulation in kidney ischemia-reperfusion injury. ( Frank, RD; Holscher, T; Mackman, N; Pawlinski, R; Sato, Y; Schabbauer, G; Tencati, M, 2005)
"To evaluate the effect of creatine supplementation in the diet of rats subjected to ischemia and reperfusion of hind limbs."4.02Effects of dietary creatine supplementation on kidney and striated skeletal muscles of rats submitted to ischemia and reperfusion of hind limbs. ( Francisco Neto, A; Moreira Neto, AA; Moreira, FMDR; Rigopoulos, L; Soufen, MA; Tsunemi, D, 2021)
"Serum metabonomic profiles of the model of focal cerebral ischemia reperfusion is established with the suture-occluded method by Longa to study the effect of ginsenosides."3.96[Effect of ginsenosides on serous metabonomic profiles in cerebral ischemia-reperfusion rats based on ~1H-NMR]. ( Cao, DM; Guan, QX; Liu, YL; Wang, SM, 2020)
"This study aims to explore the effects of the exogenous hydrogen sulfide (H2S)-mediated scavenger receptor A (SR-A) signaling pathway on renal ischemia/reperfusion injury (IRI) by regulating endoplasmic reticulum (ER) stress-induced autophagy in rats."3.85Roles of the Exogenous H2S-Mediated SR-A Signaling Pathway in Renal Ischemia/ Reperfusion Injury in Regulating Endoplasmic Reticulum Stress-Induced Autophagy in a Rat Model. ( Ling, Q; Liu, JH; Wang, SG; Wang, T; Ye, ZQ; Yu, X, 2017)
"Creatine (Cr) is a dietary supplement that presents beneficial effects in experimental models of heart and brain ischemia and reperfusion (I/R) injury."3.83Creatine supplementation attenuates pulmonary and systemic effects of lung ischemia and reperfusion injury. ( Albertini, R; Almeida, FM; Carvalho, PT; Castro-Faria-Neto, HC; Damaceno-Rodrigues, NR; Dolhnikoff, M; Lopes, FD; Martins, MA; Oliveira-Junior, MC; Pazetti, R; Petroni, RC; Soriano, FG; Soto, SF; Souza, RA; Vieira, RP, 2016)
"The PI3K p110γ-specific inhibitor, but not p110δ-specific inhibitor, significantly reduced serum creatine levels and acute tubular necrosis."3.81Reduction in Renal Ischemia-Reperfusion Injury in Mice by a Phosphoinositide 3-Kinase p110gamma-Specific Inhibitor. ( Cho, YM; Han, DJ; Hong, S; Joo, SJ; Kim, N; Kim, ST; Lee, JJ; Song, Y; Woo, CW; Woo, DC, 2015)
"These results demonstrate that pre-treatment with paricalcitol has a renoprotective effect in ischemic AKI, possibly by suppressing TLR4-NF-κB mediated inflammation."3.80Renoprotective effect of paricalcitol via a modulation of the TLR4-NF-κB pathway in ischemia/reperfusion-induced acute kidney injury. ( Cho, E; Cho, WY; Jo, SK; Kim, HK; Kim, MG; Kim, SC; Ko, YS; Lee, HY; Lee, JW, 2014)
"To investigate the effects of dietary creatine supplementation alone and in combination with exercise on basal cardiac function, susceptibility to ischaemia/reperfusion injury and mitochondrial oxidative function."3.78The effect of creatine supplementation on myocardial function, mitochondrial respiration and susceptibility to ischaemia/reperfusion injury in sedentary and exercised rats. ( Du Toit, EF; Huisamen, B; Lochner, A; Webster, I, 2012)
"The authors compared temporal profiles of N-acetylaspartate (NAA) and the NAA/total creatine ratio with neuronal and astrocytic densities and with tissue atrophy in the hippocampal CA1 sector of gerbils after 5-minute bilateral forebrain ischemia and subsequent reperfusion for up to 6 months."3.72N-acetylaspartate to total creatine ratio in the hippocampal CA1 sector after transient cerebral ischemia in gerbils: influence of neuronal elements, reactive gliosis, and tissue atrophy. ( Konaka, K; Li, JY; Matsumoto, M; Sakoda, S; Ueda, H; Yanagihara, T, 2003)
" T2 weighted-imaging (T2WI) and 1H-magnetic resonance spectroscopy (1H-MRS) were performed, to study the changes of the imaging and the neuronal metabolites N-acetyl aspartate (NAA), creatine/phosphocreatine (Cr/PCr), choline (Cho) and lactose (Lac) in cerebrum following cerebral ischemia."3.72[The effects of Erigeron breviscapus preparation on the imaging and neuronal metabolites at the early time points after reperfusion following the ischemic cerebral injury in rats]. ( Fan, M; Li, LY; Liao, WJ; Liu, ML; Yang, WT; Yang, YH, 2003)
"In this study, we used a global cerebral ischemia induced by four-vessel occlusion as an established animal model for ischemic stroke to investigate metabolic changes after 24 h reperfusion, when transitions occur due to the onset of delayed neuronal death."1.48NMR metabolomic study of blood plasma in ischemic and ischemically preconditioned rats: an increased level of ketone bodies and decreased content of glycolytic products 24 h after global cerebral ischemia. ( Baranovicova, E; Cierny, D; Grendar, M; Kalenska, D; Lehotsky, J; Tomascova, A, 2018)
"Melatonin treatment reduced the biochemical indices without any change in the cytokine levels and ameliorated histopathologic alterations induced by IR."1.34Melatonin protects from ischemia/reperfusion-induced renal injury in rats: this effect is not mediated by proinflammatory cytokines. ( Aksoy, N; Baba, F; Cakir, H; Celik, H; Gezen, MR; Kurcer, Z; Oguz, E; Ozbilge, H, 2007)
"Fondaparinux is a synthetic pentasaccharide that selectively inhibits factor Xa (FXa) in the coagulation cascade."1.33The synthetic pentasaccharide fondaparinux reduces coagulation, inflammation and neutrophil accumulation in kidney ischemia-reperfusion injury. ( Frank, RD; Holscher, T; Mackman, N; Pawlinski, R; Sato, Y; Schabbauer, G; Tencati, M, 2005)
"Ischemia-reperfusion injury is a serious clinical situation which can cause serious morbidity and mortality."1.33Role of glyceryl trinitrate, a nitric oxide donor, in the renal ischemia-reperfusion injury of rats. ( Akyol, H; Bingul, S; Colak, E; Gul, AE; Kaptanoglu, L; Kucuk, HF; Kurt, N; Ozalp, F; Torlak, OA, 2006)
"Ischemia-reperfusion injury is caused by the activation of inflammatory and cytoprotective genes, such as macrophage chemoattractant protein-1 and heme oxygenase-1, respectively."1.33Influence of bradykinin B1 and B2 receptors in the immune response triggered by renal ischemia-reperfusion injury. ( Câmara, NO; Cenedeze, MA; Pacheco-Silva, A; Pesquero, JB; Wang, PH, 2006)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.63)18.7374
1990's1 (2.63)18.2507
2000's15 (39.47)29.6817
2010's18 (47.37)24.3611
2020's3 (7.89)2.80

Authors

AuthorsStudies
Sia, PI1
Wood, JPM1
Chidlow, G1
Casson, R1
Cao, DM1
Guan, QX1
Liu, YL1
Wang, SM1
Almeida, FM2
Battochio, AS1
Napoli, JP1
Alves, KA1
Balbin, GS1
Oliveira-Junior, M1
Moriya, HT1
Pego-Fernandes, PM1
Vieira, RP2
Pazetti, R2
Moreira Neto, AA1
Francisco Neto, A1
Moreira, FMDR1
Rigopoulos, L1
Tsunemi, D1
Soufen, MA1
Ling, Q1
Yu, X1
Wang, T1
Wang, SG1
Ye, ZQ1
Liu, JH1
Baranovicova, E1
Grendar, M1
Kalenska, D1
Tomascova, A1
Cierny, D1
Lehotsky, J1
Zhang, C1
Yu, S1
Zheng, B1
Liu, D1
Wan, F1
Ma, Y1
Wang, J1
Gao, Z1
Shan, Z1
Lee, JW1
Kim, SC1
Ko, YS1
Lee, HY1
Cho, E1
Kim, MG1
Jo, SK1
Cho, WY1
Kim, HK1
Si, YN1
Bao, HG1
Xu, L1
Wang, XL1
Shen, Y1
Wang, JS1
Yang, XB1
Hosgood, SA1
Randle, LV1
Patel, M1
Watson, CJ1
Bradley, JA1
Nicholson, ML1
Ozturk, SA1
Ceylan, C1
Serel, TA1
Doluoglu, OG1
Soyupek, AS1
Guzel, A1
Özorak, A1
Uz, E1
Savas, HB1
Baspinar, S1
Oliveira-Junior, MC1
Souza, RA1
Petroni, RC1
Soto, SF1
Soriano, FG1
Carvalho, PT1
Albertini, R1
Damaceno-Rodrigues, NR1
Lopes, FD1
Castro-Faria-Neto, HC1
Martins, MA1
Dolhnikoff, M1
Kim, N1
Woo, DC1
Joo, SJ1
Song, Y1
Lee, JJ1
Woo, CW1
Kim, ST1
Hong, S1
Cho, YM1
Han, DJ1
Kocak, C1
Kocak, FE1
Akcilar, R1
Bayat, Z1
Aras, B1
Metineren, MH1
Yucel, M1
Simsek, H1
Patil, CN1
Wallace, K1
LaMarca, BD1
Moulana, M1
Lopez-Ruiz, A1
Soljancic, A1
Juncos, LA1
Grande, JP1
Reckelhoff, JF1
Moxon-Lester, L1
Takamoto, K1
Colditz, PB1
Barnett, NL1
Yang, S1
Pei, L1
Hoff, U1
Lukitsch, I1
Chaykovska, L1
Ladwig, M1
Arnold, C1
Manthati, VL1
Fuller, TF1
Schneider, W1
Gollasch, M1
Muller, DN1
Flemming, B1
Seeliger, E1
Luft, FC1
Falck, JR1
Dragun, D1
Schunck, WH1
Barrera-Chimal, J1
Pérez-Villalva, R1
Cortés-González, C1
Ojeda-Cervantes, M1
Gamba, G1
Morales-Buenrostro, LE1
Bobadilla, NA1
Snoeijs, MG1
Hoogland, PR1
Boonen, B1
Coffman, TM1
Peutz-Kootstra, CJ1
Buurman, WA1
van Heurn, LW1
Orsenigo, MN1
Porta, C1
Sironi, C1
Laforenza, U1
Meyer, G1
Tosco, M1
Webster, I1
Du Toit, EF1
Huisamen, B1
Lochner, A1
Wang, HP1
Liu, CW1
Chang, HW1
Tsai, JW1
Sung, YZ1
Chang, LC1
Sahna, E1
Parlakpinar, H1
Ozturk, F1
Cigremis, Y1
Acet, A1
Konaka, K1
Ueda, H1
Li, JY1
Matsumoto, M1
Sakoda, S1
Yanagihara, T1
Liao, WJ1
Yang, YH1
Fan, M1
Yang, WT1
Li, LY1
Liu, ML1
Frank, RD1
Schabbauer, G1
Holscher, T1
Sato, Y1
Tencati, M1
Pawlinski, R1
Mackman, N1
Montie, HL1
Kayali, F1
Haezebrouck, AJ1
Rossi, NF1
Degracia, DJ1
Sener, G2
Sert, G1
Ozer Sehirli, A1
Arbak, S1
Gedik, N2
Ayanoğlu-Dülger, G1
Xiao, LJ1
Li, YJ1
Yu, YM1
Pan, XH1
Cao, LY1
Yang, YQ1
Kucuk, HF1
Kaptanoglu, L1
Ozalp, F1
Kurt, N1
Bingul, S1
Torlak, OA1
Colak, E1
Akyol, H1
Gul, AE1
Tuğtepe, H1
Yüksel, M1
Cetinel, S1
Yeğen, BC1
Wang, PH1
Cenedeze, MA1
Pesquero, JB1
Pacheco-Silva, A1
Câmara, NO1
Kurcer, Z1
Oguz, E1
Ozbilge, H1
Baba, F1
Aksoy, N1
Celik, H1
Cakir, H1
Gezen, MR1
Wu, H1
Chen, G1
Wyburn, KR1
Yin, J1
Bertolino, P1
Eris, JM1
Alexander, SI1
Sharland, AF1
Chadban, SJ1
Kuro, T1
Kobayashi, Y1
Takaoka, M1
Matsumura, Y1
Peart, J1
Headrick, JP1
Neglén, P1
Jabs, CM1
Eklöf, B1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pilot Non Randomised Controlled Trial of Short Term Spironolactone Use for Prevention of Acute Kidney Injury After Cardiac Surgery[NCT02417896]150 participants (Anticipated)Interventional2013-04-30Recruiting
Usefulness of Spironolactone for the Prevention of Acute Kidney Injury in Critically Ill Patients With Invasive Mechanical Ventilation[NCT03206658]Phase 390 participants (Anticipated)Interventional2017-08-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

38 other studies available for creatine and Reperfusion Injury

ArticleYear
Creatine is Neuroprotective to Retinal Neurons In Vitro But Not In Vivo.
    Investigative ophthalmology & visual science, 2019, 10-01, Volume: 60, Issue:13

    Topics: Animals; Blotting, Western; Cell Survival; Cells, Cultured; Creatine; Creatine Kinase; Electroretino

2019
[Effect of ginsenosides on serous metabonomic profiles in cerebral ischemia-reperfusion rats based on ~1H-NMR].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2020, Volume: 45, Issue:5

    Topics: 3-Hydroxybutyric Acid; Animals; Brain Ischemia; Creatine; Ginsenosides; Hemolymph; Metabolome; Phosp

2020
Creatine Supply Attenuates Ischemia-Reperfusion Injury in Lung Transplantation in Rats.
    Nutrients, 2020, Sep-10, Volume: 12, Issue:9

    Topics: Animals; Antioxidants; Apoptosis; Cell Proliferation; Creatine; Dietary Supplements; Lung; Lung Tran

2020
Effects of dietary creatine supplementation on kidney and striated skeletal muscles of rats submitted to ischemia and reperfusion of hind limbs.
    Acta cirurgica brasileira, 2021, Volume: 36, Issue:3

    Topics: Animals; Creatine; Diet; Dietary Supplements; Ischemia; Kidney; Male; Muscle, Skeletal; Rats; Rats,

2021
Roles of the Exogenous H2S-Mediated SR-A Signaling Pathway in Renal Ischemia/ Reperfusion Injury in Regulating Endoplasmic Reticulum Stress-Induced Autophagy in a Rat Model.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 41, Issue:6

    Topics: Animals; Autophagy; Creatine; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Endoplasm

2017
NMR metabolomic study of blood plasma in ischemic and ischemically preconditioned rats: an increased level of ketone bodies and decreased content of glycolytic products 24 h after global cerebral ischemia.
    Journal of physiology and biochemistry, 2018, Volume: 74, Issue:3

    Topics: Acetic Acid; Animals; Biomarkers; Blood Glucose; Brain Ischemia; Cerebrovascular Disorders; Creatine

2018
miR-30c-5p Reduces Renal Ischemia-Reperfusion Involving Macrophage.
    Medical science monitor : international medical journal of experimental and clinical research, 2019, Jun-11, Volume: 25

    Topics: Acute Kidney Injury; Animals; Creatine; Humans; Inflammation; Kidney; Lipocalin-2; Macrophages; Male

2019
Renoprotective effect of paricalcitol via a modulation of the TLR4-NF-κB pathway in ischemia/reperfusion-induced acute kidney injury.
    Biochemical and biophysical research communications, 2014, Feb-07, Volume: 444, Issue:2

    Topics: Acute Kidney Injury; Animals; Blotting, Western; Cell Line; Chemokine CCL2; Chemokines; Creatine; Er

2014
Dexmedetomidine protects against ischemia/reperfusion injury in rat kidney.
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:13

    Topics: Acute-Phase Proteins; Animals; Apoptosis; Biomarkers; Blood Urea Nitrogen; Creatine; Cystatin C; Dex

2014
Sildenafil citrate in a donation after circulatory death experimental model of renal ischemia-reperfusion injury.
    Transplantation, 2014, Sep-27, Volume: 98, Issue:6

    Topics: Animals; Area Under Curve; Cold Ischemia; Creatine; Cyclic GMP; Endothelin-1; Kidney; Kidney Transpl

2014
Protective effect of theophylline on renal functions in experimental pneumoperitoneum model.
    Renal failure, 2015, Volume: 37, Issue:6

    Topics: Acute Kidney Injury; Animals; Biomarkers; Biopsy, Needle; Creatine; Cystatin C; Disease Models, Anim

2015
Creatine supplementation attenuates pulmonary and systemic effects of lung ischemia and reperfusion injury.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2016, Volume: 35, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Blotting, Western; Creati

2016
Reduction in Renal Ischemia-Reperfusion Injury in Mice by a Phosphoinositide 3-Kinase p110gamma-Specific Inhibitor.
    Transplantation, 2015, Volume: 99, Issue:10

    Topics: Animals; Cell Movement; Chemokine CXCL9; Class I Phosphatidylinositol 3-Kinases; Class Ib Phosphatid

2015
Effects of captopril, telmisartan and bardoxolone methyl (CDDO-Me) in ischemia-reperfusion-induced acute kidney injury in rats: an experimental comparative study.
    Clinical and experimental pharmacology & physiology, 2016, Volume: 43, Issue:2

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Antioxidants; Apoptosis; Arginine; Benzimidazole

2016
Low-dose testosterone protects against renal ischemia-reperfusion injury by increasing renal IL-10-to-TNF-α ratio and attenuating T-cell infiltration.
    American journal of physiology. Renal physiology, 2016, 08-01, Volume: 311, Issue:2

    Topics: Animals; Creatine; Cytokines; Enzyme Inhibitors; Interleukin-10; Kidney; Kidney Diseases; Male; NG-N

2016
S-adenosyl-L-methionine restores photoreceptor function following acute retinal ischemia.
    Visual neuroscience, 2009, Volume: 26, Issue:5-6

    Topics: Acute Disease; Administration, Oral; Animals; Blindness; Creatine; Electroretinography; Female; Huma

2009
[Influence of rhBMP-2 on the renal tissue of rat with renal ischemia reperfusion injury and its molecular mechanism].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2009, Volume: 44, Issue:10

    Topics: Adrenal Cortex; Animals; Blood Urea Nitrogen; Bone Morphogenetic Protein 2; Creatine; Interleukin-6;

2009
Inhibition of 20-HETE synthesis and action protects the kidney from ischemia/reperfusion injury.
    Kidney international, 2011, Volume: 79, Issue:1

    Topics: Acute Kidney Injury; Animals; Apoptosis; Creatine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-

2011
Hsp72 is an early and sensitive biomarker to detect acute kidney injury.
    EMBO molecular medicine, 2011, Volume: 3, Issue:1

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Biomarkers; Creatine; Hepatitis A Virus Cellular

2011
Hsp72 is an early and sensitive biomarker to detect acute kidney injury.
    EMBO molecular medicine, 2011, Volume: 3, Issue:1

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Biomarkers; Creatine; Hepatitis A Virus Cellular

2011
Hsp72 is an early and sensitive biomarker to detect acute kidney injury.
    EMBO molecular medicine, 2011, Volume: 3, Issue:1

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Biomarkers; Creatine; Hepatitis A Virus Cellular

2011
Hsp72 is an early and sensitive biomarker to detect acute kidney injury.
    EMBO molecular medicine, 2011, Volume: 3, Issue:1

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Biomarkers; Creatine; Hepatitis A Virus Cellular

2011
Thromboxane receptor signalling in renal ischemia reperfusion injury.
    Free radical research, 2011, Volume: 45, Issue:6

    Topics: Acute Kidney Injury; Animals; Antioxidants; Blood Urea Nitrogen; Creatine; F2-Isoprostanes; Gene Del

2011
Effects of creatine in a rat intestinal model of ischemia/reperfusion injury.
    European journal of nutrition, 2012, Volume: 51, Issue:3

    Topics: Animals; Antioxidants; Creatine; Gene Expression Regulation; HSP70 Heat-Shock Proteins; Hypoxia; Ile

2012
The effect of creatine supplementation on myocardial function, mitochondrial respiration and susceptibility to ischaemia/reperfusion injury in sedentary and exercised rats.
    Acta physiologica (Oxford, England), 2012, Volume: 206, Issue:1

    Topics: Animals; Creatine; Dietary Supplements; Male; Mitochondria, Heart; Myocardial Infarction; Organ Cult

2012
Cordyceps sinensis protects against renal ischemia/reperfusion injury in rats.
    Molecular biology reports, 2013, Volume: 40, Issue:3

    Topics: Adenosine; Animals; Cellular Senescence; Chemokine CXCL12; Cordyceps; Creatine; Disease Models, Anim

2013
The protective effects of physiological and pharmacological concentrations of melatonin on renal ischemia-reperfusion injury in rats.
    Urological research, 2003, Volume: 31, Issue:3

    Topics: Animals; Antioxidants; Blood Urea Nitrogen; Creatine; Dose-Response Relationship, Drug; Free Radical

2003
N-acetylaspartate to total creatine ratio in the hippocampal CA1 sector after transient cerebral ischemia in gerbils: influence of neuronal elements, reactive gliosis, and tissue atrophy.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2003, Volume: 23, Issue:6

    Topics: Animals; Aspartic Acid; Astrocytes; Atrophy; Cell Count; Common Variable Immunodeficiency; Creatine;

2003
[The effects of Erigeron breviscapus preparation on the imaging and neuronal metabolites at the early time points after reperfusion following the ischemic cerebral injury in rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2003, Volume: 28, Issue:2

    Topics: Animals; Aspartic Acid; Asteraceae; Brain; Brain Ischemia; Choline; Creatine; Drugs, Chinese Herbal;

2003
The synthetic pentasaccharide fondaparinux reduces coagulation, inflammation and neutrophil accumulation in kidney ischemia-reperfusion injury.
    Journal of thrombosis and haemostasis : JTH, 2005, Volume: 3, Issue:3

    Topics: Animals; Blood Coagulation; Cell Movement; Chemokine CXCL2; Creatine; Drug Evaluation, Preclinical;

2005
Renal ischemia and reperfusion activates the eIF 2 alpha kinase PERK.
    Biochimica et biophysica acta, 2005, Sep-25, Volume: 1741, Issue:3

    Topics: Animals; Blotting, Western; Creatine; eIF-2 Kinase; Epithelial Cells; Gene Expression Regulation, En

2005
Melatonin protects against pressure ulcer-induced oxidative injury of the skin and remote organs in rats.
    Journal of pineal research, 2006, Volume: 40, Issue:3

    Topics: Administration, Topical; Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Urea Nitr

2006
[Effect of autologous bone marrow stem cell transplantation on renal function following renal ischemic-reperfusion in rabbits].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2006, Volume: 26, Issue:5

    Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Bone Marrow Cells; Creatine; Female; Hematopoieti

2006
Role of glyceryl trinitrate, a nitric oxide donor, in the renal ischemia-reperfusion injury of rats.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2006, Volume: 38, Issue:5

    Topics: Animals; Blood Urea Nitrogen; Creatine; Glomerular Filtration Rate; Kidney; Nitric Oxide; Nitric Oxi

2006
Resveratrol improves ischemia/reperfusion-induced oxidative renal injury in rats.
    Archives of medical research, 2006, Volume: 37, Issue:7

    Topics: Acridines; Animals; Antioxidants; Blood Urea Nitrogen; Creatine; Glutathione; Kidney Diseases; L-Lac

2006
Influence of bradykinin B1 and B2 receptors in the immune response triggered by renal ischemia-reperfusion injury.
    International immunopharmacology, 2006, Dec-20, Volume: 6, Issue:13-14

    Topics: Animals; Chemokine CCL2; Creatine; Gene Expression; Heme Oxygenase-1; Inflammation; Kidney; Male; Mi

2006
Melatonin protects from ischemia/reperfusion-induced renal injury in rats: this effect is not mediated by proinflammatory cytokines.
    Journal of pineal research, 2007, Volume: 43, Issue:2

    Topics: Animals; Creatine; Cytokines; Kidney; Male; Melatonin; Nitrogen; Oxidative Stress; Phenols; Plant Ex

2007
TLR4 activation mediates kidney ischemia/reperfusion injury.
    The Journal of clinical investigation, 2007, Volume: 117, Issue:10

    Topics: Animals; Apoptosis; Biglycan; Chemokines; Chimera; Creatine; Cytokines; Extracellular Matrix Protein

2007
Protective effect of KB-R7943, a novel Na+/Ca2+ exchange inhibitor, on ischemic acute renal failure in rats.
    Japanese journal of pharmacology, 1999, Volume: 81, Issue:2

    Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Creatine; Kidney; Kidney Function Tests; Male; Ra

1999
Intrinsic A(1) adenosine receptor activation during ischemia or reperfusion improves recovery in mouse hearts.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:5

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Creatine; Extracellular Space; He

2000
Plasma metabolic disturbances and reperfusion injury following partial limb ischaemia in man.
    European journal of vascular surgery, 1989, Volume: 3, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Aged; Arterial Occlusive Diseases; Blood Vesse

1989