Page last updated: 2024-10-17

creatine and Renal Insufficiency, Chronic

creatine has been researched along with Renal Insufficiency, Chronic in 38 studies

Renal Insufficiency, Chronic: Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)

Research Excerpts

ExcerptRelevanceReference
"Proteinuria was observed in 27% of 153 patients taking tenofovir for more than 1 year."7.79Tenofovir-associated proteinuria. ( Bartlett, H; Gibson, A; Kelly, MD; Patten, J; Rowling, D, 2013)
"We found that Cordyceps preparation, as an adjuvant therapy to conventional medicine, showed potential promise to decrease serum creatinine, increase creatine clearance, reduce proteinuria and alleviate CKD-associated complications, such as increased haemoglobin and serum albumin."4.90Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease. ( Chan, LS; Kwan, TH; Leung, C; Lin, ZX; Mok, CK; Tung, YS; Zhang, HW, 2014)
"Creatine is an essential contributor to cellular energy homeostasis, yet, on a daily basis, 1."4.11Chronic Dialysis Patients Are Depleted of Creatine: Review and Rationale for Intradialytic Creatine Supplementation. ( Appeldoorn, TYJ; Bakker, SJL; Franssen, CFM; Heiner-Fokkema, MR; Koops, CA; Kremer, D; Marsman, E; Post, A; Touw, DJ; van der Veen, Y; Wallimann, T; Westerhuis, R, 2021)
"Proteinuria was observed in 27% of 153 patients taking tenofovir for more than 1 year."3.79Tenofovir-associated proteinuria. ( Bartlett, H; Gibson, A; Kelly, MD; Patten, J; Rowling, D, 2013)
"Patients with chronic kidney disease and type 2 diabetes have a higher risk of developing pneumonia as well as an increased risk of severe COVID-19-associated adverse events and mortality."3.11Association of Finerenone Use With Reduction in Treatment-Emergent Pneumonia and COVID-19 Adverse Events Among Patients With Type 2 Diabetes and Chronic Kidney Disease: A FIDELITY Pooled Secondary Analysis. ( Agarwal, R; Ahlers, C; Anker, SD; Brinker, M; Filippatos, GS; Joseph, A; Lambelet, M; Lawatscheck, R; Pitt, B; Rossing, P; Ruilope, LM, 2022)
"Creatine is an essential contributor in cellular energy homeostasis, yet on a daily basis 1."2.61Creatine is a Conditionally Essential Nutrient in Chronic Kidney Disease: A Hypothesis and Narrative Literature Review. ( Bakker, SJL; Post, A; Tsikas, D, 2019)
" Risedronate was safe and effective in osteoporotic women with mild, moderate, or severe age-related renal impairment."2.43Safety and efficacy of risedronate in patients with age-related reduced renal function as estimated by the Cockcroft and Gault method: a pooled analysis of nine clinical trials. ( Barton, IP; Boonen, S; Burgio, DE; Dunlap, LE; Miller, PD; Roux, C, 2005)
"Vascular calcification is a risk factor for causing cardiovascular events and has a high prevalence among chronic kidney disease (CKD) patients."1.42High phosphorus level leads to aortic calcification via β-catenin in chronic kidney disease. ( Fan, X; Feng, JM; Liu, LL; Ma, JF; Ren, C; Sun, L; Sun, W; Sun, YT; Wang, LN; Xu, TH; Yao, L, 2015)
"Asymmetric dimethylarginine (ADMA) has been suggested as a possible marker of endothelial dysfunction, and interest in its use in clinical practice is increasing."1.36HPLC determination of plasma dimethylarginines: method validation and preliminary clinical application. ( Artusi, C; Boffa, GM; Ivanova, M; Plebani, M; Zaninotto, M, 2010)
"Creatine is an amino acid which is a precursor of creatinine, and is known to transiently increase serum creatinine."1.34How we estimate GFR--a pitfall of using a serum creatinine-based formula. ( Kanagasundaram, NS; Moochhala, SH; Refaie, R, 2007)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19903 (7.89)18.7374
1990's0 (0.00)18.2507
2000's2 (5.26)29.6817
2010's23 (60.53)24.3611
2020's10 (26.32)2.80

Authors

AuthorsStudies
Dong, Y1
Silver, SM1
Sterns, RH1
Chen, SJ1
Tseng, CC1
Huang, KH1
Chang, YC1
Fu, LM1
Khattri, RB1
Kim, K1
Anderson, EM1
Fazzone, B1
Harland, KC1
Hu, Q1
Palzkill, VR1
Cort, TA1
O'Malley, KA1
Berceli, SA1
Scali, ST1
Ryan, TE1
Xu, LY1
Hui, M1
Zhu, SH1
Yang, Z1
Li, MR1
Yang, HY1
Zheng, XZ1
Lv, JC1
Yang, L1
Pitt, B1
Agarwal, R1
Anker, SD1
Ruilope, LM1
Rossing, P1
Ahlers, C1
Brinker, M1
Joseph, A1
Lambelet, M1
Lawatscheck, R1
Filippatos, GS1
Ding, K1
Li, Z1
Lu, Y1
Sun, L2
Ochiai, H1
Shirasawa, T1
Yoshimoto, T1
Nagahama, S1
Watanabe, A1
Sakamoto, K1
Kokaze, A1
Saud, A1
Luiz, RS1
Leite, APO1
Muller, CR1
Visona, I1
Reinecke, N1
Silva, WH1
Gloria, MA1
Razvickas, CV1
Casarini, DE1
Schor, N1
Hashimoto, T1
Shibata, K1
Honda, K1
Nobe, K1
van der Veen, Y1
Post, A2
Kremer, D1
Koops, CA1
Marsman, E1
Appeldoorn, TYJ1
Touw, DJ1
Westerhuis, R1
Heiner-Fokkema, MR1
Franssen, CFM1
Wallimann, T1
Bakker, SJL2
Nash, DM1
Garg, AX1
Brimble, KS1
Markle-Reid, M1
Medrano Navarro, AL1
Justel Enríquez, A1
Alameda Serrano, J1
Blasco Lamarca, Y1
Sáenz Abad, D1
Gimeno Orna, JA1
Tsikas, D1
Lopes, MB1
Araújo, LQ1
Passos, MT1
Nishida, SK1
Kirsztajn, GM1
Cendoroglo, MS1
Sesso, RC1
Lin, YC1
Bansal, N1
Vittinghoff, E1
Go, AS1
Hsu, CY1
Nagai, K1
Doi, T1
Rayane, R1
Yu, B1
Zheng, Y1
Nettleton, JA1
Alexander, D1
Coresh, J1
Boerwinkle, E1
Koo, HS1
Kim, YC1
Ahn, SY2
Oh, SW1
Kim, S3
Chin, HJ2
Kim, DK1
Park, JH1
Shin, SJ1
Lee, SH1
Choi, BS1
Lim, CS1
Stack, AG1
Casserly, LF1
Cronin, CJ1
Chernenko, T1
Cullen, W1
Hannigan, A1
Saran, R1
Johnson, H1
Browne, G1
Ferguson, JP1
Chase, HS1
Hirsch, JS1
Mohan, S1
Rao, MK1
Radhakrishnan, J1
Zhang, HW1
Lin, ZX1
Tung, YS1
Kwan, TH1
Mok, CK1
Leung, C1
Chan, LS1
Yao, L1
Sun, YT1
Sun, W1
Xu, TH1
Ren, C1
Fan, X1
Liu, LL1
Feng, JM1
Ma, JF1
Wang, LN1
Benito, S1
Sánchez, A1
Unceta, N1
Andrade, F1
Aldámiz-Echevarria, L1
Goicolea, MA1
Barrio, RJ1
Norouzi, J1
Yadollahpour, A1
Mirbagheri, SA1
Mazdeh, MM1
Hosseini, SA1
Neild, GH1
Park, JI1
Baek, H1
Jung, HH1
Ivanova, M1
Artusi, C1
Boffa, GM1
Zaninotto, M1
Plebani, M1
Kelly, MD1
Gibson, A1
Bartlett, H1
Rowling, D1
Patten, J1
Shafat, I1
Agbaria, A1
Boaz, M1
Schwartz, D1
Baruch, R1
Nakash, R1
Ilan, N1
Vlodavsky, I1
Weinstein, T1
Imamura, T1
Kinugawa, K1
Shiga, T1
Kato, N1
Muraoka, H1
Minatsuki, S1
Inaba, T1
Maki, H1
Hatano, M1
Yao, A1
Kyo, S1
Nagai, R1
McIntyre, NJ1
Fluck, RJ1
McIntyre, CW1
Fakis, A1
Taal, MW1
TOBIAS, GJ1
McLAUGHLIN, RF1
HOPPER, J1
TOIVANEN, P1
SAARIMAA, HA1
FONKEN, HA1
ELLIS, PP1
Miller, PD1
Roux, C1
Boonen, S1
Barton, IP1
Dunlap, LE1
Burgio, DE1
Refaie, R1
Moochhala, SH1
Kanagasundaram, NS1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter, Event-driven Phase 3 Study to Investigate the Safety and Efficacy of Finerenone, in Addition to Standard of Care, on the Progression of Kidney Disease in Subjects With Type 2 Dia[NCT02540993]Phase 35,734 participants (Actual)Interventional2015-09-17Completed
A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter, Event-driven Phase 3 Study to Investigate Efficacy and Safety of Finerenone on the Reduction of Cardiovascular Morbidity and Mortality in Subjects With Type 2 Diabetes Mellitus a[NCT02545049]Phase 37,352 participants (Actual)Interventional2015-09-17Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

All-cause Hospitalization

Count of participants and time from randomization to the first occurrence of a hospitalization event were evaluated. Number of participants with the event is reported as descriptive result and hazard ratio is reported as statistical analysis. (NCT02540993)
Timeframe: From randomization up until the first occurrence of the hospitalization due to any cause, or censoring at the end of study, with an average of 32 months

InterventionParticipants (Count of Participants)
Finerenone1263
Placebo1321

All-cause Mortality

Count of participants and time from randomization until death due to any cause were evaluated. Number of participants with outcome death is reported as descriptive result and hazard ratio is reported as statistical analysis. Number of participants with outcome death reported here includes deaths occurred after randomization until the end of the study visit. Deaths after end of study visit are not included in this table. (NCT02540993)
Timeframe: From randomization up until death due to any cause, or censoring at the end of the study visit, with an average of 32 months

InterventionParticipants (Count of Participants)
Finerenone219
Placebo244

Change in Urinary Albumin-to-creatinine Ratio (UACR) From Baseline to Month 4

First morning void urine samples were collected to evaluate the urinary albumin-to-creatinine ratio (UACR). Month 4 was the visit closest to day 120 within a time window of 120 ± 30 days after randomization. If no measurements were available in this time window, the participant was excluded from this analysis. Ratio of UACR at Month 4 to UACR at baseline is reported as the change. (NCT02540993)
Timeframe: From baseline up until Month 4

InterventionRatio (Least Squares Mean)
Finerenone0.655
Placebo0.952

The First Occurrence of the Composite Endpoint of Cardiovascular Death, Non-fatal Myocardial Infarction, Non-fatal Stroke, or Hospitalization for Heart Failure

Count of participants and time from randomization to the first occurrence of the key secondary cardiovascular (CV) composite outcome, CV death, non-fatal myocardial infarction (MI), non-fatal stroke, or hospitalization for heart failure were evaluated. Number of participants with the outcome event is reported as descriptive result and hazard ratio is reported as statistical analysis. (NCT02540993)
Timeframe: From randomization up until the first occurrence of the key secondary CV composite endpoint, or censoring at the end of the study, with an average of 32 months

InterventionParticipants (Count of Participants)
Finerenone367
Placebo420

The First Occurrence of the Composite Endpoint of Onset of Kidney Failure, a Sustained Decrease in eGFR of ≥57% From Baseline Over at Least 4 Weeks, or Renal Death

Count of participants and time from randomization to the first occurrence of the secondary renal composite outcome, onset of kidney failure, a sustained decrease in eGFR of ≥57% from baseline over at least 4 weeks, or renal death were evaluated. Number of participants with the outcome event is reported as descriptive result and hazard ratio is reported as statistical analysis. (NCT02540993)
Timeframe: From randomization up until the first occurrence of the composite primary endpoint, or censoring at the end of the study, with an average of 32 months

InterventionParticipants (Count of Participants)
Finerenone252
Placebo326

The First Occurrence of the Composite Endpoint of Onset of Kidney Failure, a Sustained Decrease of eGFR ≥40% From Baseline Over at Least 4 Weeks, or Renal Death

Count of participants and time from randomization to the first occurrence of the primary renal composite outcome, onset of kidney failure, a sustained decrease of eGFR ≥40% from baseline over at least 4 weeks, or renal death were evaluated. Number of participants with the outcome event is reported as descriptive result and hazard ratio is reported as statistical analysis. (NCT02540993)
Timeframe: From randomization up until the first occurrence of the primary renal composite endpoint, or censoring at the end of the study, with an average follow-up time of 32 months

InterventionParticipants (Count of Participants)
Finerenone504
Placebo600

All-cause Hospitalization

Number of participants with first occurrence of a hospitalization event were reported as descriptive result. (NCT02545049)
Timeframe: From randomization up until the first occurrence of the hospitalization due to any cause, or censoring at the end of study, with an average study duration of 41 months

InterventionParticipants (Count of Participants)
Finerenone1573
Placebo1605

All-cause Mortality

Number of participants with death due to any cause were reported as descriptive result. Number of participants with outcome death reported here includes deaths occurred after randomization until the end of the study visit. Deaths after end of study visit are not included in this table. (NCT02545049)
Timeframe: From randomization up until death due to any cause, or censoring at the end of the study, with an average study duration of 41 months

InterventionParticipants (Count of Participants)
Finerenone333
Placebo370

Change in Urinary Albumin-to-creatine Ratio (UCAR) From Baseline to Month 4

First morning void urine samples were collected to evaluate the urinary albumin-to-creatinine ratio (UACR). Month 4 was the visit closest to day 120 within a time window of 120 ± 30 days after randomization. If no measurements were available in this time window, the participant was excluded from this analysis. Ratio of UACR at Month 4 to UACR at baseline is reported as the change. (NCT02545049)
Timeframe: From baseline up until Month 4

InterventionRatio (Least Squares Mean)
Finerenone0.624
Placebo0.922

The First Occurrence of the Composite Endpoint of Cardiovascular Death, Non-fatal Myocardial Infarction, Non Fatal Stroke, or Hospitalization for Heart Failure.

Number of participants with the first occurrence of the primary cardiovascular (CV) composite outcome, CV death, non-fatal myocardial infarction (MI), non-fatal stroke, or hospitalization for heart failure were reported as descriptive result. (NCT02545049)
Timeframe: From randomization up until the first occurrence of the CV composite endpoint, or censoring at the end of the study, with an average study duration of 41 months.

InterventionParticipants (Count of Participants)
Finerenone458
Placebo519

The First Occurrence of the Composite Endpoint of Onset of Kidney Failure, a Sustained Decrease in eGFR of ≥57% From Baseline Over at Least 4 Weeks, or Renal Death

Number of participants with first occurrence of the renal composite outcome, onset of kidney failure, a sustained decrease in eGFR of ≥57% from baseline over at least 4 weeks, or renal death were reported as descriptive result. (NCT02545049)
Timeframe: From randomization up until the first occurrence of the renal composite endpoint, or censoring at the end of the study, with an average study duration of 41 months

InterventionParticipants (Count of Participants)
Finerenone108
Placebo139

The First Occurrence of the Composite Endpoint of Onset of Kidney Failure, a Sustained Decrease of eGFR ≥40% From Baseline Over at Least 4 Weeks, or Renal Death.

Number of participants with first occurrence of the composite endpoint of onset of kidney failure, a sustained decrease of eGFR ≥40% from baseline over at least 4 weeks, or renal death were reported as descriptive result. (NCT02545049)
Timeframe: From randomization up until the first occurrence of the renal composite endpoint, or censoring at the end of the study, with an average study duration of 41 months.

InterventionParticipants (Count of Participants)
Finerenone350
Placebo395

Reviews

7 reviews available for creatine and Renal Insufficiency, Chronic

ArticleYear
Estimating urine volume from the urine creatinine concentration.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2023, 03-31, Volume: 38, Issue:4

    Topics: Aged; Creatine; Creatinine; Glomerular Filtration Rate; Humans; Kidney Function Tests; Obesity, Morb

2023
Chronic Dialysis Patients Are Depleted of Creatine: Review and Rationale for Intradialytic Creatine Supplementation.
    Nutrients, 2021, Aug-06, Volume: 13, Issue:8

    Topics: Creatine; Dietary Supplements; Double-Blind Method; Health Status; Humans; Netherlands; Pilot Projec

2021
Creatine is a Conditionally Essential Nutrient in Chronic Kidney Disease: A Hypothesis and Narrative Literature Review.
    Nutrients, 2019, May-10, Volume: 11, Issue:5

    Topics: Creatine; Diet; Humans; Nutrients; Renal Insufficiency, Chronic

2019
[New era of laboratory testing. Topics: II. Particulars; 3. Laboratory examination for the diagnosis of CKD or AKI].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2013, Dec-10, Volume: 102, Issue:12

    Topics: Acute Kidney Injury; Biomarkers; Creatine; Cystatin C; Diagnostic Techniques, Urological; Humans; Re

2013
Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease.
    The Cochrane database of systematic reviews, 2014, Dec-18, Issue:12

    Topics: Cordyceps; Creatine; Creatinine; Humans; Phytotherapy; Proteinuria; Randomized Controlled Trials as

2014
Life expectancy with chronic kidney disease: an educational review.
    Pediatric nephrology (Berlin, Germany), 2017, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Age Factors; Cardiovascular Diseases; Child; Creatine; Female; Glomerular Filtrat

2017
Safety and efficacy of risedronate in patients with age-related reduced renal function as estimated by the Cockcroft and Gault method: a pooled analysis of nine clinical trials.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2005, Volume: 20, Issue:12

    Topics: Age Factors; Aged; Aged, 80 and over; Algorithms; Bone Density; Bone Density Conservation Agents; Bo

2005

Trials

3 trials available for creatine and Renal Insufficiency, Chronic

ArticleYear
Association of Finerenone Use With Reduction in Treatment-Emergent Pneumonia and COVID-19 Adverse Events Among Patients With Type 2 Diabetes and Chronic Kidney Disease: A FIDELITY Pooled Secondary Analysis.
    JAMA network open, 2022, 10-03, Volume: 5, Issue:10

    Topics: Albumins; Anti-Inflammatory Agents; COVID-19; Creatine; Diabetes Mellitus, Type 2; Diabetic Nephropa

2022
Association of Finerenone Use With Reduction in Treatment-Emergent Pneumonia and COVID-19 Adverse Events Among Patients With Type 2 Diabetes and Chronic Kidney Disease: A FIDELITY Pooled Secondary Analysis.
    JAMA network open, 2022, 10-03, Volume: 5, Issue:10

    Topics: Albumins; Anti-Inflammatory Agents; COVID-19; Creatine; Diabetes Mellitus, Type 2; Diabetic Nephropa

2022
Association of Finerenone Use With Reduction in Treatment-Emergent Pneumonia and COVID-19 Adverse Events Among Patients With Type 2 Diabetes and Chronic Kidney Disease: A FIDELITY Pooled Secondary Analysis.
    JAMA network open, 2022, 10-03, Volume: 5, Issue:10

    Topics: Albumins; Anti-Inflammatory Agents; COVID-19; Creatine; Diabetes Mellitus, Type 2; Diabetic Nephropa

2022
Association of Finerenone Use With Reduction in Treatment-Emergent Pneumonia and COVID-19 Adverse Events Among Patients With Type 2 Diabetes and Chronic Kidney Disease: A FIDELITY Pooled Secondary Analysis.
    JAMA network open, 2022, 10-03, Volume: 5, Issue:10

    Topics: Albumins; Anti-Inflammatory Agents; COVID-19; Creatine; Diabetes Mellitus, Type 2; Diabetic Nephropa

2022
Chronic Dialysis Patients Are Depleted of Creatine: Review and Rationale for Intradialytic Creatine Supplementation.
    Nutrients, 2021, Aug-06, Volume: 13, Issue:8

    Topics: Creatine; Dietary Supplements; Double-Blind Method; Health Status; Humans; Netherlands; Pilot Projec

2021
Novel criteria of urine osmolality effectively predict response to tolvaptan in decompensated heart failure patients--association between non-responders and chronic kidney disease.
    Circulation journal : official journal of the Japanese Circulation Society, 2013, Volume: 77, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidiuretic Hormone Receptor Antagonists; Benzazepines;

2013

Other Studies

29 other studies available for creatine and Renal Insufficiency, Chronic

ArticleYear
Microfluidic Sliding Paper-Based Device for Point-of-Care Determination of Albumin-to-Creatine Ratio in Human Urine.
    Biosensors, 2022, Jul-07, Volume: 12, Issue:7

    Topics: Albumins; Creatine; Creatinine; Humans; Microfluidics; Point-of-Care Systems; Renal Insufficiency, C

2022
Metabolomic profiling reveals muscle metabolic changes following iliac arteriovenous fistula creation in mice.
    American journal of physiology. Renal physiology, 2022, 11-01, Volume: 323, Issue:5

    Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Arteriovenous Fistula; Arterioven

2022
[Chronic kidney disease in community: Current state for screening and management].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2022, Oct-18, Volume: 54, Issue:5

    Topics: Albuminuria; Blood Glucose; Creatine; Glomerular Filtration Rate; Humans; Renal Insufficiency, Chron

2022
Efficacy and safety assessment of mineralocorticoid receptor antagonists in patients with chronic kidney disease.
    European journal of internal medicine, 2023, Volume: 115

    Topics: Bayes Theorem; Cardiovascular Diseases; Creatine; Diabetes Mellitus, Type 2; Diabetic Nephropathies;

2023
Elevated alanine aminotransferase and low aspartate aminotransferase/alanine aminotransferase ratio are associated with chronic kidney disease among middle-aged women: a cross-sectional study.
    BMC nephrology, 2020, 11-10, Volume: 21, Issue:1

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Creatine; Cross-Sectional Studies; Female; gamma-

2020
Resistance exercise training ameliorates chronic kidney disease outcomes in a 5/6 nephrectomy model.
    Life sciences, 2021, Jun-15, Volume: 275

    Topics: Animals; Creatine; Disease Models, Animal; Male; Nephrectomy; Rats; Rats, Wistar; Renal Insufficienc

2021
Acetic acid treatment causes renal inflammation and chronic kidney disease in mice.
    Journal of pharmacological sciences, 2021, Volume: 146, Issue:3

    Topics: Acetic Acid; Animals; Creatine; Disease Models, Animal; Gene Expression; Interleukin-1beta; Kidney;

2021
Primary care provider perceptions of enablers and barriers to following guideline-recommended laboratory tests to confirm chronic kidney disease: a qualitative descriptive study.
    BMC family practice, 2018, 12-10, Volume: 19, Issue:1

    Topics: Adult; Biomarkers; Creatine; Decision Making; Female; Guideline Adherence; Health Knowledge, Attitud

2018
Total and cardiovascular mortality risk according to KDIGO guidelines classification in type 2 diabetic patients.
    Medicina clinica, 2019, 10-11, Volume: 153, Issue:7

    Topics: Adult; Albuminuria; Analysis of Variance; Cardiovascular Diseases; Cause of Death; Chi-Square Distri

2019
Estimation of glomerular filtration rate from serum creatinine and cystatin C in octogenarians and nonagenarians.
    BMC nephrology, 2013, Dec-02, Volume: 14

    Topics: Aged, 80 and over; Algorithms; Biomarkers; Brazil; Creatine; Cystatin C; Diagnosis, Computer-Assiste

2013
Determinants of the creatinine clearance to glomerular filtration rate ratio in patients with chronic kidney disease: a cross-sectional study.
    BMC nephrology, 2013, Dec-05, Volume: 14

    Topics: Albuminuria; Algorithms; Comorbidity; Creatine; Cross-Sectional Studies; Diagnosis, Computer-Assiste

2013
[Medical practice in support of hypertension as risk factor kidney in general medical practice, and primary prevention in children in schools, and the pregnant woman in Annaba (Algeria)].
    Annales de cardiologie et d'angeiologie, 2014, Volume: 63, Issue:3

    Topics: Adult; Algeria; Antihypertensive Agents; Biomarkers; Blood Pressure Determination; Child; Creatine;

2014
Serum metabolomic profiling and incident CKD among African Americans.
    Clinical journal of the American Society of Nephrology : CJASN, 2014, Aug-07, Volume: 9, Issue:8

    Topics: Biomarkers; Black or African American; Chromatography, Liquid; Creatine; Cross-Sectional Studies; De

2014
Analysis of correlation between 24-hour urinary sodium and the degree of blood pressure control in patients with chronic kidney disease and non-chronic kidney disease.
    Journal of Korean medical science, 2014, Volume: 29 Suppl 2

    Topics: Adult; Aged; Algorithms; Blood Pressure; Creatine; Demography; Female; Humans; Hypertension; Male; M

2014
Urinary sodium excretion has positive correlation with activation of urinary renin angiotensin system and reactive oxygen species in hypertensive chronic kidney disease.
    Journal of Korean medical science, 2014, Volume: 29 Suppl 2

    Topics: Adult; Aged; Angiotensinogen; Chemokine CCL2; Creatine; Demography; Female; Follow-Up Studies; Human

2014
Prevalence and variation of Chronic Kidney Disease in the Irish health system: initial findings from the National Kidney Disease Surveillance Programme.
    BMC nephrology, 2014, Nov-25, Volume: 15

    Topics: Adolescent; Adult; Creatine; Demography; Female; Humans; Ireland; Male; Middle Aged; Morbidity; Popu

2014
Presence of early CKD-related metabolic complications predict progression of stage 3 CKD: a case-controlled study.
    BMC nephrology, 2014, Nov-27, Volume: 15

    Topics: Acidosis; Aged; Aged, 80 and over; Anemia; Bicarbonates; Calcium; Case-Control Studies; Creatine; Di

2014
High phosphorus level leads to aortic calcification via β-catenin in chronic kidney disease.
    American journal of nephrology, 2015, Volume: 41, Issue:1

    Topics: Actins; Animals; Aorta; beta Catenin; Blood Urea Nitrogen; Calcium; Cells, Cultured; Core Binding Fa

2015
LC-QTOF-MS-based targeted metabolomics of arginine-creatine metabolic pathway-related compounds in plasma: application to identify potential biomarkers in pediatric chronic kidney disease.
    Analytical and bioanalytical chemistry, 2016, Volume: 408, Issue:3

    Topics: Adolescent; Adult; Arginine; Biomarkers; Child; Child, Preschool; Chromatography, High Pressure Liqu

2016
Predicting Renal Failure Progression in Chronic Kidney Disease Using Integrated Intelligent Fuzzy Expert System.
    Computational and mathematical methods in medicine, 2016, Volume: 2016

    Topics: Adult; Aged; Artificial Intelligence; Blood Pressure; Calcium; Creatine; Disease Progression; Expert

2016
Prevalence of Chronic Kidney Disease in Korea: the Korean National Health and Nutritional Examination Survey 2011-2013.
    Journal of Korean medical science, 2016, Volume: 31, Issue:6

    Topics: Adult; Aged; Albuminuria; Creatine; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Middle

2016
HPLC determination of plasma dimethylarginines: method validation and preliminary clinical application.
    Clinica chimica acta; international journal of clinical chemistry, 2010, Nov-11, Volume: 411, Issue:21-22

    Topics: Adolescent; Adult; Aged; Arginine; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Cr

2010
Tenofovir-associated proteinuria.
    AIDS (London, England), 2013, Jan-28, Volume: 27, Issue:3

    Topics: Adenine; Anti-HIV Agents; Creatine; Female; HIV Infections; Humans; Male; Middle Aged; Organophospho

2013
Elevated urine heparanase levels are associated with proteinuria and decreased renal allograft function.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Creatine; Female; Glomerular Filtration Rate; Glucuronidase; Humans;

2012
Determinants of arterial stiffness in chronic kidney disease stage 3.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Albuminuria; Blood Pressure; Body Mass Index; Cardiovascular D

2013
Endogenous creatinine clearance. A valuable clinical test of glomerular filtration and a prognostic guide in chronic renal disease.
    The New England journal of medicine, 1962, Feb-15, Volume: 266

    Topics: Creatine; Creatinine; Humans; Kidney Failure, Chronic; Kidney Function Tests; Prognosis; Renal Insuf

1962
AXON REFLEX SWEATING IN CHRONIC NEPHROPATHY.
    Annales medicinae internae Fenniae, 1964, Volume: 53

    Topics: Axons; Blood; Creatine; Creatinine; Humans; Kidney Diseases; Nicotine; Physiology; Reflex; Renal Ins

1964
RETINOPATHIES OF CHRONIC RENAL DISEASE; REVERSALS AFTER RENAL TRANSPLANTATION.
    Annals of internal medicine, 1965, Volume: 62

    Topics: Arteriosclerosis; Blood Pressure; Blood Urea Nitrogen; Child; Creatine; Creatinine; Glomerulonephrit

1965
How we estimate GFR--a pitfall of using a serum creatinine-based formula.
    Clinical nephrology, 2007, Volume: 68, Issue:4

    Topics: Adult; Creatine; Creatinine; Diagnosis, Differential; Dietary Supplements; Glomerular Filtration Rat

2007