Page last updated: 2024-10-17

creatine and Pain

creatine has been researched along with Pain in 15 studies

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to ascertain whether an oral, non-prescription, nutritional supplement compound composed of a proprietary alkali-buffered creatine monohydrate and cetylated fatty acids mixture (Kre-Celazine(®)) was efficacious in reducing or eliminating refractory pain and inflammation, without untoward effects, in Juvenile Rheumatoid Arthritis (JRA), which is also called Juvenile Idiopathic Arthritis (JIA)."5.19Kre-Celazine(®) as a viable treatment for juvenile rheumatoid arthritis/juvenile idiopathic arthritis - a pilot study. ( Golini, J; Jones, WL, 2014)
"The objective of this study was to evaluate creatine as an anti-nociceptive compound in an animal model of thermal and inflammatory pain."3.88Effects of creatine supplementation on nociception in young male and female mice. ( Gonzales, EB; Izurieta Munoz, H; Sumien, N, 2018)
" It discusses dosage modifications appropriate for the geriatric population and reviews the drugs available to alleviate pain."2.44Pharmacotherapeutic management of pain with a focus directed at the geriatric patient. ( Barkin, DS; Barkin, RL; Barkin, SJ, 2007)
"More pain was associated with reduced GMVs and NAA/Cr, over and above the effects of fatigue, depressive symptoms, physical activity, and psychomotor speed."1.46Prefrontal Structure Varies as a Function of Pain Symptoms in Chronic Fatigue Syndrome. ( De Lange, FP; Geurts, DEM; Knoop, H; Roelofs, K; Schmits, IC; Toni, I; van der Meer, JWM; van der Schaaf, ME, 2017)
"In patients with breast cancer and skin metastases, topically applied miltefosine solution yields at least partial regression of the lesions in approximately a quarter of patients when used as an adjunct to standard treatment (surgery, radiotherapy, systemic chemotherapy or hormone therapy) or when standard treatments are contraindicated."1.30Miltefosine: new preparation. Solution for cutaneous application. ( , 1998)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's1 (6.67)18.2507
2000's5 (33.33)29.6817
2010's8 (53.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schwartz, JA1
Portnoy, J1
Izurieta Munoz, H1
Gonzales, EB1
Sumien, N1
Golini, J1
Jones, WL1
Fayed, N1
Andrés, E1
Viguera, L1
Modrego, PJ1
Garcia-Campayo, J1
van der Schaaf, ME1
De Lange, FP1
Schmits, IC1
Geurts, DEM1
Roelofs, K1
van der Meer, JWM1
Toni, I1
Knoop, H1
Gussew, A1
Rzanny, R1
Erdtel, M1
Scholle, HC1
Kaiser, WA1
Mentzel, HJ1
Reichenbach, JR1
Shewmon, DA1
Craig, JM1
Neves, M1
Gualano, B1
Roschel, H1
Fuller, R1
Benatti, FB1
Pinto, AL1
Lima, FR1
Pereira, RM1
Lancha, AH1
Bonfá, E1
Rosendal, L1
Larsson, B1
Kristiansen, J1
Peolsson, M1
Søgaard, K1
Kjær, M1
Sørensen, J1
Gerdle, B1
Culp, FB1
Kinard, FW1
Barkin, RL1
Barkin, SJ1
Barkin, DS1
Rawson, ES1
Conti, MP1
Miles, MP1
Sorensen, L1
Siddall, PJ1
Trenell, MI1
Yue, DK1
Chlebna-Sokół, D1
Loba-Jakubowska, E1
Sikora, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Project Arthritis Recovering Quality of Life Through Education 70+[NCT04058002]34 participants (Anticipated)Interventional2019-08-15Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for creatine and Pain

ArticleYear
Pharmacotherapeutic management of pain with a focus directed at the geriatric patient.
    Rheumatic diseases clinics of North America, 2007, Volume: 33, Issue:1

    Topics: Aged; Chronic Disease; Creatine; Diabetic Neuropathies; Geriatric Assessment; Geriatrics; Humans; Pa

2007

Trials

3 trials available for creatine and Pain

ArticleYear
Kre-Celazine(®) as a viable treatment for juvenile rheumatoid arthritis/juvenile idiopathic arthritis - a pilot study.
    Journal of medicinal food, 2014, Volume: 17, Issue:9

    Topics: Adolescent; Analgesics; Anti-Inflammatory Agents; Arthritis, Juvenile; Blood Sedimentation; C-Reacti

2014
Beneficial effect of creatine supplementation in knee osteoarthritis.
    Medicine and science in sports and exercise, 2011, Volume: 43, Issue:8

    Topics: Creatine; Dietary Supplements; Double-Blind Method; Exercise Therapy; Female; Humans; Middle Aged; M

2011
Creatine supplementation does not reduce muscle damage or enhance recovery from resistance exercise.
    Journal of strength and conditioning research, 2007, Volume: 21, Issue:4

    Topics: Adult; Athletic Injuries; Biomarkers; C-Reactive Protein; Creatine; Creatine Kinase; Dietary Supplem

2007

Other Studies

11 other studies available for creatine and Pain

ArticleYear
Lower catecholamine activity is associated with greater levels of anger in adults.
    International journal of psychophysiology : official journal of the International Organization of Psychophysiology, 2017, Volume: 120

    Topics: Adult; Aged; Aged, 80 and over; Anger; Autonomic Nervous System; Catecholamines; Creatine; Eating; E

2017
Effects of creatine supplementation on nociception in young male and female mice.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:2

    Topics: Acid Sensing Ion Channels; Analgesics; Animals; Creatine; Disease Models, Animal; Female; Ganglia, S

2018
Higher glutamate+glutamine and reduction of N-acetylaspartate in posterior cingulate according to age range in patients with cognitive impairment and/or pain.
    Academic radiology, 2014, Volume: 21, Issue:9

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aspartic Acid; Case-Control Studies; Cognition Disorder

2014
Prefrontal Structure Varies as a Function of Pain Symptoms in Chronic Fatigue Syndrome.
    Biological psychiatry, 2017, 02-15, Volume: 81, Issue:4

    Topics: Adolescent; Adult; Aspartic Acid; Creatine; Fatigue Syndrome, Chronic; Female; Glutamates; Gray Matt

2017
Time-resolved functional 1H MR spectroscopic detection of glutamate concentration changes in the brain during acute heat pain stimulation.
    NeuroImage, 2010, Jan-15, Volume: 49, Issue:2

    Topics: Acute Disease; Adult; Aspartic Acid; Cerebral Cortex; Choline; Creatine; Glutamic Acid; Hot Temperat

2010
Creatine supplementation prevents statin-induced muscle toxicity.
    Annals of internal medicine, 2010, Nov-16, Volume: 153, Issue:10

    Topics: Creatine; Dietary Supplements; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Muscle Cramp;

2010
Increase in muscle nociceptive substances and anaerobic metabolism in patients with trapezius myalgia: microdialysis in rest and during exercise.
    Pain, 2004, Volume: 112, Issue:3

    Topics: Creatine; Female; Glutamic Acid; Humans; L-Lactate Dehydrogenase; Lactic Acid; Microdialysis; Muscle

2004
EFFECT OF CREATINE ON THE PAIN OF MUSCLE ISCHEMIA.
    The Journal of clinical investigation, 1947, Volume: 26, Issue:2

    Topics: Creatine; Creatinine; Humans; Ischemia; Muscles; Pain

1947
Differences in metabolites in pain-processing brain regions in patients with diabetes and painful neuropathy.
    Diabetes care, 2008, Volume: 31, Issue:5

    Topics: Adult; Aged; Aspartic Acid; Brain; Brain Mapping; Choline; Creatine; Diabetic Neuropathies; Female;

2008
Miltefosine: new preparation. Solution for cutaneous application.
    Prescrire international, 1998, Volume: 7, Issue:33

    Topics: Administration, Cutaneous; Antineoplastic Agents; Blood Cell Count; Breast Neoplasms; Clinical Trial

1998
Clinical evaluation of patients with idiopathic juvenile osteoporosis.
    Journal of pediatric orthopedics. Part B, 2001, Volume: 10, Issue:3

    Topics: Absorptiometry, Photon; Acute Disease; Adolescent; Alkaline Phosphatase; Body Mass Index; Bone Densi

2001