creatine has been researched along with Nervous System Disorders in 17 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Inborn errors of metabolism have been identified in the three main steps involved in creatine metabolism: arginine:glycine amidinotransferase (AGAT), S-adenosyl-L-methionine:N-guanidinoacetate methyltransferase (GAMT), and the creatine transporter." | 2.41 | Health implications of creatine: can oral creatine supplementation protect against neurological and atherosclerotic disease? ( Schulze, A; Wyss, M, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 11 (64.71) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chilosi, A | 1 |
| Leuzzi, V | 2 |
| Battini, R | 2 |
| Tosetti, M | 1 |
| Ferretti, G | 1 |
| Comparini, A | 1 |
| Casarano, M | 1 |
| Moretti, E | 1 |
| Alessandri, MG | 1 |
| Bianchi, MC | 1 |
| Cioni, G | 1 |
| Xu, V | 1 |
| Chan, H | 1 |
| Lin, AP | 1 |
| Sailasuta, N | 1 |
| Valencerina, S | 1 |
| Tran, T | 1 |
| Hovener, J | 1 |
| Ross, BD | 1 |
| Bodamer, OA | 1 |
| Iqbal, F | 1 |
| Mühl, A | 1 |
| Hung, C | 1 |
| Prayer, D | 1 |
| Ratschmann, R | 1 |
| Item, BC | 1 |
| de Andrade, RB | 1 |
| Gemelli, T | 1 |
| Rojas, DB | 1 |
| Funchal, C | 1 |
| Dutra-Filho, CS | 1 |
| Wannmacher, CM | 1 |
| Magnus, T | 1 |
| Röther, J | 1 |
| Simova, O | 1 |
| Meier-Cillien, M | 1 |
| Repenthin, J | 1 |
| Möller, F | 1 |
| Gbadamosi, J | 1 |
| Panzer, U | 1 |
| Wengenroth, M | 1 |
| Hagel, C | 1 |
| Kluge, S | 1 |
| Stahl, RK | 1 |
| Wegscheider, K | 1 |
| Urban, P | 1 |
| Eckert, B | 1 |
| Glatzel, M | 1 |
| Fiehler, J | 1 |
| Gerloff, C | 1 |
| Cheillan, D | 1 |
| Joncquel-Chevalier Curt, M | 1 |
| Briand, G | 1 |
| Salomons, GS | 1 |
| Mention-Mulliez, K | 1 |
| Dobbelaere, D | 1 |
| Cuisset, JM | 1 |
| Lion-François, L | 1 |
| Portes, VD | 1 |
| Chabli, A | 1 |
| Valayannopoulos, V | 1 |
| Benoist, JF | 1 |
| Pinard, JM | 1 |
| Simard, G | 1 |
| Douay, O | 1 |
| Deiva, K | 1 |
| Afenjar, A | 1 |
| Héron, D | 1 |
| Rivier, F | 1 |
| Chabrol, B | 1 |
| Prieur, F | 1 |
| Cartault, F | 1 |
| Pitelet, G | 1 |
| Goldenberg, A | 1 |
| Bekri, S | 1 |
| Gerard, M | 1 |
| Delorme, R | 1 |
| Tardieu, M | 1 |
| Porchet, N | 1 |
| Vianey-Saban, C | 1 |
| Vamecq, J | 1 |
| Chang, L | 1 |
| Cloak, CC | 1 |
| Ernst, T | 1 |
| Baker, SK | 1 |
| Tarnopolsky, MA | 2 |
| Ryu, H | 1 |
| Rosas, HD | 1 |
| Hersch, SM | 1 |
| Ferrante, RJ | 1 |
| Carducci, C | 2 |
| Santagata, S | 1 |
| Artiola, C | 1 |
| Giovanniello, T | 1 |
| Antonozzi, I | 1 |
| Brosnan, JT | 1 |
| Brosnan, ME | 1 |
| Edden, RA | 1 |
| Bonekamp, D | 1 |
| Smith, MA | 1 |
| Dubey, P | 1 |
| Barker, PB | 1 |
| Bernasconi, A | 1 |
| Cendes, F | 1 |
| Shoubridge, EA | 1 |
| Andermann, E | 1 |
| Li, LM | 1 |
| Arnold, DL | 1 |
| Andermann, F | 1 |
| Beal, MF | 1 |
| Wyss, M | 1 |
| Schulze, A | 1 |
| Berlet, HH | 1 |
| Pilz, H | 1 |
| Bernhardt, W | 1 |
| Eickhoff, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Remote Effects of Stroke on Cerebral Metabolism. Evaluation With Positron Emission Tomography and Proton Magnetic Resonance Spectroscopy[NCT00063180] | 70 participants | Observational | 2003-06-19 | Completed | |||
| An Investigation Examining the Evidence for Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder[NCT00327756] | Phase 2 | 0 participants (Actual) | Interventional | 2006-05-31 | Withdrawn | ||
| Premanifest Huntington's Disease: Creatine Safety & Tolerability Extension Study[NCT01411150] | Phase 2 | 38 participants (Actual) | Interventional | 2009-05-31 | Completed | ||
| Creatine Safety, Tolerability, & Efficacy in Huntington's Disease (CREST-E)[NCT00712426] | Phase 3 | 553 participants (Actual) | Interventional | 2009-09-30 | Terminated (stopped due to Results of an interim analysis showed that it was unlikely that creatine was effective in slowing loss of function in early symptomatic Huntington's Disease.) | ||
| Premanifest Huntington's Disease Extension Study II: Creatine Safety & Tolerability[NCT01411163] | Phase 2 | 24 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| Creatine Safety and Tolerability in Premanifest HD: PRECREST[NCT00592995] | Phase 2 | 64 participants (Actual) | Interventional | 2007-12-31 | Completed | ||
| Creatine Safety & Tolerability in Huntington's Disease (CREST-X): A Single-Center, Open-Label, Long-Term Safety & Tolerability Extension Study of Creatine in Subjects With HD[NCT01412151] | Phase 2 | 10 participants (Actual) | Interventional | 2005-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Proportion of subjects able to complete treatment (NCT01412151)
Timeframe: 306 Weeks
| Intervention | Participants (Number) |
|---|---|
| Creatine Monohydrate | 5 |
7 reviews available for creatine and Nervous System Disorders
| Article | Year |
|---|---|
MR spectroscopy in diagnosis and neurological decision-making.
Topics: Aspartic Acid; Choline; Creatine; Decision Making; Humans; Magnetic Resonance Spectroscopy; Nervous | 2008 |
Magnetic resonance spectroscopy studies of GABA in neuropsychiatric disorders.
Topics: Anxiety Disorders; Brain; Brain Chemistry; Creatine; Depressive Disorder; Epilepsy; GABA Agents; gam | 2003 |
Targeting cellular energy production in neurological disorders.
Topics: Amyotrophic Lateral Sclerosis; Animals; Coenzymes; Creatine; Disease Models, Animal; Energy Metaboli | 2003 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
The therapeutic role of creatine in Huntington's disease.
Topics: Animals; Creatine; Humans; Huntington Disease; Nervous System Diseases | 2005 |
Creatine: endogenous metabolite, dietary, and therapeutic supplement.
Topics: Brain; Creatine; Dietary Supplements; Humans; Muscle, Skeletal; Nervous System Diseases; Nutritional | 2007 |
Potential for creatine and other therapies targeting cellular energy dysfunction in neurological disorders.
Topics: Animals; Creatine; Energy Metabolism; Humans; Nervous System Diseases | 2001 |
Health implications of creatine: can oral creatine supplementation protect against neurological and atherosclerotic disease?
Topics: Administration, Oral; Animals; Arteriosclerosis; Creatine; Dietary Supplements; Female; Humans; Male | 2002 |
10 other studies available for creatine and Nervous System Disorders
| Article | Year |
|---|---|
Treatment with L-arginine improves neuropsychological disorders in a child with creatine transporter defect.
Topics: Arginine; Behavioral Symptoms; Brain; Brain Diseases, Metabolic, Inborn; Child; Cognition; Creatine; | 2008 |
Low creatinine: the diagnostic clue for a treatable neurologic disorder.
Topics: Biomarkers; Creatine; Creatinine; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Infant; Mal | 2009 |
Tyrosine impairs enzymes of energy metabolism in cerebral cortex of rats.
Topics: Adenylate Kinase; Animals; Cerebral Cortex; Creatine; Disease Models, Animal; Energy Metabolism; Enz | 2012 |
The neurological syndrome in adults during the 2011 northern German E. coli serotype O104:H4 outbreak.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antigens, CD; Blood Urea Nitrogen; Cerebral Cortex; Coho | 2012 |
Screening for primary creatine deficiencies in French patients with unexplained neurological symptoms.
Topics: Creatine; Creatinine; Female; Glycine; Humans; Male; Nerve Tissue Proteins; Nervous System Diseases; | 2012 |
Quantitative determination of guanidinoacetate and creatine in dried blood spot by flow injection analysis-electrospray tandem mass spectrometry.
Topics: Amidinotransferases; Child; Child, Preschool; Chromatography, High Pressure Liquid; Creatine; Glycin | 2006 |
Proton MR spectroscopic imaging of the medulla and cervical spinal cord.
Topics: Adult; Brain; Choline; Creatine; Female; Humans; Image Processing, Computer-Assisted; Magnetic Reson | 2007 |
Spectroscopic imaging of frontal neuronal dysfunction in hyperekplexia.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Choline; Creatine; Female; Frontal Lobe; Humans; Magnetic R | 1998 |
[Significance of plasma creatine and neurologic disorders for the creatine level of cerebrospinal fluid in man].
Topics: Amyotrophic Lateral Sclerosis; Creatine; Dementia; Encephalitis; Epilepsy; Humans; Meningitis; Multi | 1972 |
[Prognosis in neurogenic and myogenic paresis: the aid of laboratory findings (author's transl)].
Topics: Creatine; Electromyography; Humans; Muscular Atrophy; Muscular Diseases; Nervous System Diseases; Pa | 1974 |