creatine has been researched along with Nerve Degeneration in 29 studies
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors examined the levels of NAA, creatine plus phosphocreatine, and choline-containing molecules in the left dorsolateral prefrontal cortex of 14 bipolar disorder patients (mean age=15." | 3.73 | Reduced NAA levels in the dorsolateral prefrontal cortex of young bipolar patients. ( Axelson, D; Birmaher, B; Brambilla, P; Keshavan, MS; Nicoletti, MA; Ramos, RT; Ryan, N; Sassi, RB; Soares, JC; Stanley, JA, 2005) |
| "Autosomal-dominant spinocerebellar ataxia type 1 (SCA1) is an adult-onset progressive disorder with well-characterized neurodegeneration in the cerebellum and brainstem." | 1.40 | Metabolic evidence for cerebral neurodegeneration in spinocerebellar ataxia type 1. ( Brandt, AU; Doss, S; Endres, M; Oberwahrenbrock, T; Paul, F; Rinnenthal, JL, 2014) |
| "We used a mouse model of transient middle cerebral artery occlusion." | 1.35 | In vivo neuroprotection by a creatine-derived compound: phosphocreatine-Mg-complex acetate. ( Adriano, E; Balestrino, M; Burov, SV; Gandolfo, C; Perasso, L; Ruggeri, P, 2009) |
| "Creatine-treated subjects had significantly smaller ABR threshold shifts on day 1 and on day 10." | 1.34 | Creatine and tempol attenuate noise-induced hearing loss. ( Miller, JM; Minami, SB; Ogawa, K; Schacht, J; Yamashita, D, 2007) |
| "The study included 12 patients with progressive supranuclear palsy, 10 with Parkinson's disease, nine with corticobasal degeneration and 11 age-matched normal control subjects." | 1.30 | Proton magnetic resonance spectroscopic imaging in progressive supranuclear palsy, Parkinson's disease and corticobasal degeneration. ( Bertolino, A; Bonavita, S; Hallett, M; Litvan, I; Lundbom, N; Patronas, NJ; Tedeschi, G, 1997) |
| "Four grades of demyelination and three grades of cerebral atrophy were distinguished by magnetic resonance imaging criteria." | 1.28 | 1H and 31P magnetic resonance spectroscopy of the brain in degenerative cerebral disorders. ( den Hollander, JA; Luyten, PR; Nauta, JJ; Valk, J; van der Grond, J; van der Knaap, MS, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (31.03) | 18.2507 |
| 2000's | 15 (51.72) | 29.6817 |
| 2010's | 5 (17.24) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Doss, S | 1 |
| Brandt, AU | 1 |
| Oberwahrenbrock, T | 1 |
| Endres, M | 1 |
| Paul, F | 1 |
| Rinnenthal, JL | 1 |
| Erichsen, AK | 1 |
| Server, A | 1 |
| Landrø, NI | 1 |
| Sandvik, L | 1 |
| Tallaksen, CM | 1 |
| Rákóczi, K | 1 |
| Klivényi, P | 2 |
| Vécsei, L | 1 |
| Perasso, L | 1 |
| Adriano, E | 1 |
| Ruggeri, P | 1 |
| Burov, SV | 1 |
| Gandolfo, C | 1 |
| Balestrino, M | 1 |
| Atmaca, M | 1 |
| Yildirim, H | 1 |
| Ozdemir, H | 1 |
| Koc, M | 1 |
| Ozler, S | 1 |
| Tezcan, E | 1 |
| Qian, J | 1 |
| Herrera, JJ | 1 |
| Narayana, PA | 1 |
| Xu, W | 1 |
| Zhan, Y | 1 |
| Huang, W | 1 |
| Wang, X | 1 |
| Zhang, S | 1 |
| Lei, H | 1 |
| Brockmann, K | 1 |
| Hilker, R | 1 |
| Pilatus, U | 1 |
| Baudrexel, S | 1 |
| Srulijes, K | 1 |
| Magerkurth, J | 1 |
| Hauser, AK | 1 |
| Schulte, C | 1 |
| Csoti, I | 1 |
| Merten, CD | 1 |
| Gasser, T | 1 |
| Berg, D | 1 |
| Hattingen, E | 1 |
| Davydovskaia, MV | 1 |
| Boĭko, AN | 1 |
| Podoprigora, AE | 1 |
| Pronin, IN | 1 |
| Kornienko, VN | 1 |
| Gusev, EI | 1 |
| Calingasan, NY | 1 |
| Starkov, A | 1 |
| Stavrovskaya, IG | 1 |
| Kristal, BS | 1 |
| Yang, L | 1 |
| Wieringa, B | 1 |
| Beal, MF | 1 |
| Lodi, R | 1 |
| Tonon, C | 1 |
| Vignatelli, L | 1 |
| Iotti, S | 1 |
| Montagna, P | 1 |
| Barbiroli, B | 1 |
| Plazzi, G | 1 |
| Sassi, RB | 1 |
| Stanley, JA | 1 |
| Axelson, D | 1 |
| Brambilla, P | 1 |
| Nicoletti, MA | 1 |
| Keshavan, MS | 1 |
| Ramos, RT | 1 |
| Ryan, N | 1 |
| Birmaher, B | 1 |
| Soares, JC | 1 |
| Boucard, CC | 1 |
| Hoogduin, JM | 1 |
| van der Grond, J | 2 |
| Cornelissen, FW | 1 |
| Minami, SB | 1 |
| Yamashita, D | 1 |
| Ogawa, K | 1 |
| Schacht, J | 1 |
| Miller, JM | 1 |
| Funchal, C | 1 |
| Tramontina, F | 1 |
| Quincozes dos Santos, A | 1 |
| Fraga de Souza, D | 1 |
| Gonçalves, CA | 1 |
| Pessoa-Pureur, R | 1 |
| Wajner, M | 1 |
| Casey, PA | 1 |
| McKenna, MC | 1 |
| Fiskum, G | 1 |
| Saraswati, M | 1 |
| Robertson, CL | 1 |
| Rango, M | 1 |
| Spagnoli, D | 1 |
| Tomei, G | 1 |
| Bamonti, F | 1 |
| Scarlato, G | 1 |
| Zetta, L | 1 |
| Ohara, I | 1 |
| Tabuchi, R | 1 |
| Kimura, M | 1 |
| Itokawa, Y | 1 |
| Choe, BY | 1 |
| Suh, TS | 1 |
| Choi, KH | 1 |
| Shinn, KS | 1 |
| Park, CK | 1 |
| Kang, JK | 1 |
| Tedeschi, G | 2 |
| Bertolino, A | 2 |
| Massaquoi, SG | 1 |
| Campbell, G | 1 |
| Patronas, NJ | 2 |
| Bonavita, S | 2 |
| Barnett, AS | 1 |
| Alger, JR | 1 |
| Hallett, M | 2 |
| Maier, M | 2 |
| Ron, MA | 2 |
| Barker, GJ | 1 |
| Tofts, PS | 1 |
| Litvan, I | 1 |
| Lundbom, N | 1 |
| Deicken, RF | 1 |
| Zhou, L | 1 |
| Schuff, N | 1 |
| Weiner, MW | 1 |
| Simone, IL | 1 |
| Tortorella, C | 1 |
| Federico, F | 1 |
| Liguori, M | 1 |
| Lucivero, V | 1 |
| Giannini, P | 1 |
| Carrara, D | 1 |
| Bellacosa, A | 1 |
| Livrea, P | 1 |
| Khiat, A | 1 |
| Yared, Z | 1 |
| Bard, C | 1 |
| Lacroix, A | 1 |
| Boulanger, Y | 1 |
| Massieu, L | 1 |
| Del Río, P | 1 |
| Montiel, T | 1 |
| Murata, T | 1 |
| Kimura, H | 1 |
| Omori, M | 1 |
| Kado, H | 1 |
| Kosaka, H | 1 |
| Iidaka, T | 1 |
| Itoh, H | 1 |
| Wada, Y | 1 |
| van der Knaap, MS | 1 |
| Luyten, PR | 1 |
| den Hollander, JA | 1 |
| Nauta, JJ | 1 |
| Valk, J | 1 |
1 review available for creatine and Nerve Degeneration
| Article | Year |
|---|---|
[Neuroprotection in Parkinson's disease and other neurodegenerative disorders: preclinical and clinical findings].
Topics: Animals; Creatine; Dopamine Agonists; Glatiramer Acetate; Humans; Indans; Kynurenic Acid; Micronutri | 2009 |
28 other studies available for creatine and Nerve Degeneration
| Article | Year |
|---|---|
Metabolic evidence for cerebral neurodegeneration in spinocerebellar ataxia type 1.
Topics: Adult; Aged; Analysis of Variance; Aspartic Acid; Brain; Cerebral Cortex; Choline; Creatine; Female; | 2014 |
Proton magnetic resonance spectroscopy and cognition in patients with spastin mutations.
Topics: Adenosine Triphosphatases; Adult; Aspartic Acid; Biomarkers; Choline; Cognition Disorders; Creatine; | 2009 |
In vivo neuroprotection by a creatine-derived compound: phosphocreatine-Mg-complex acetate.
Topics: Animals; Brain Infarction; Brain Ischemia; Creatine; Cytoprotection; Disease Models, Animal; Infarct | 2009 |
Neurochemistry of the hippocampus in patients with obsessive-compulsive disorder.
Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Choline; Creatine; Female; Functional Laterality; | 2009 |
Neuronal and axonal degeneration in experimental spinal cord injury: in vivo proton magnetic resonance spectroscopy and histology.
Topics: Animals; Aspartic Acid; Choline; Creatine; Disease Models, Animal; Disease Progression; Gliosis; Imm | 2010 |
Reduction of hippocampal N-acetyl aspartate level in aged APP(Swe)/PS1(dE9) transgenic mice is associated with degeneration of CA3 pyramidal neurons.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Benzothiazoles; CA | 2010 |
GBA-associated PD. Neurodegeneration, altered membrane metabolism, and lack of energy failure.
Topics: Adenosine Diphosphate; Adult; Age of Onset; Aged; Algorithms; Aspartic Acid; Brain Chemistry; Cholin | 2012 |
[The neurodegenerative process in multiple sclerosis and the possible neuroprotective effect of treatment with Β-interferon 1a (avonex)].
Topics: Adolescent; Adult; Aspartic Acid; Brain Chemistry; Creatine; Female; Humans; Interferon beta-1a; Int | 2012 |
Neuroprotective mechanisms of creatine occur in the absence of mitochondrial creatine kinase.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine Monophosphate; Animals; Brain; Brain Chemistry; Chromatogr | 2004 |
In vivo evidence of neuronal loss in the hypothalamus of narcoleptic patients.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Atrophy; Cataplexy; Creatine; Female; Humans; Hypothalamus; | 2004 |
Reduced NAA levels in the dorsolateral prefrontal cortex of young bipolar patients.
Topics: Adolescent; Adult; Age Factors; Aspartic Acid; Bipolar Disorder; Child; Choline; Creatine; Female; H | 2005 |
Occipital proton magnetic resonance spectroscopy (1H-MRS) reveals normal metabolite concentrations in retinal visual field defects.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Biomarkers; Choline; Creatine; Female; Glaucoma; Humans; Mac | 2007 |
Creatine and tempol attenuate noise-induced hearing loss.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Auditory Threshold; Cochlea; Creatine; Cyclic N-Oxide | 2007 |
Effect of the branched-chain alpha-keto acids accumulating in maple syrup urine disease on S100B release from glial cells.
Topics: Animals; Brain; Cell Death; Cell Line, Tumor; Creatine; Dose-Response Relationship, Drug; Energy Met | 2007 |
Early and sustained alterations in cerebral metabolism after traumatic brain injury in immature rats.
Topics: Aging; Alanine; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Injuries; Cell Respiration; C | 2008 |
Central nervous system trans-synaptic effects of acute axonal injury: a 1H magnetic resonance spectroscopy study.
Topics: Animals; Aspartic Acid; Axons; Creatine; Female; Geniculate Bodies; Guinea Pigs; Magnetic Resonance | 1995 |
Decline of taste sensitivity in protein deficient adult rats.
Topics: Age Factors; Animals; Creatine; Female; Food Preferences; Glomerular Filtration Rate; Microscopy, El | 1995 |
Neuronal dysfunction in patients with closed head injury evaluated by in vivo 1H magnetic resonance spectroscopy.
Topics: Algorithms; Aspartic Acid; Cerebral Cortex; Choline; Creatine; Energy Metabolism; Glasgow Coma Scale | 1995 |
Proton magnetic resonance spectroscopic imaging in patients with cerebellar degeneration.
Topics: Adult; Aged; Aspartic Acid; Atrophy; Cerebellar Diseases; Cerebellum; Choline; Creatine; Humans; Lac | 1996 |
Proton magnetic resonance spectroscopy: an in vivo method of estimating hippocampal neuronal depletion in schizophrenia.
Topics: Adult; Choline Deficiency; Creatine; Female; Functional Laterality; Hippocampus; Humans; Magnetic Re | 1995 |
Hippocampal age-related changes in schizophrenia: a proton magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Age Factors; Aging; Aspartic Acid; Choline; Creatine; Female; Functional Laterali | 1996 |
Proton magnetic resonance spectroscopic imaging in progressive supranuclear palsy, Parkinson's disease and corticobasal degeneration.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Diseases; Choline; Creatine; Female; Humans; Ma | 1997 |
Proton magnetic resonance spectroscopy of the anterior cingulate region in schizophrenia.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Brain Mapping; Choline; Creatine; Dominance, Cerebral; F | 1997 |
Axonal damage in multiple sclerosis plaques: a combined magnetic resonance imaging and 1H-magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Aspartic Acid; Axons; Brain; Choline; Creatine; Female; Humans; Lactic Acid; Magn | 2001 |
Long-term brain metabolic alterations in exogenous Cushing's syndrome as monitored by proton magnetic resonance spectroscopy.
Topics: Adult; Aspartic Acid; Brain; Brain Diseases, Metabolic; Brain Injuries; Cell Membrane; Choline; Crea | 2001 |
Neurotoxicity of glutamate uptake inhibition in vivo: correlation with succinate dehydrogenase activity and prevention by energy substrates.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Amino Acid Transport System X-AG; Animals; Brain Ischemia; Con | 2001 |
MRI white matter hyperintensities, (1)H-MR spectroscopy and cognitive function in geriatric depression: a comparison of early- and late-onset cases.
Topics: Aged; Alzheimer Disease; Aspartic Acid; Brain; Choline; Creatine; Depressive Disorder, Major; Energy | 2001 |
1H and 31P magnetic resonance spectroscopy of the brain in degenerative cerebral disorders.
Topics: Adult; Aspartic Acid; Atrophy; Brain; Brain Diseases; Child; Creatine; Demyelinating Diseases; Human | 1992 |