Page last updated: 2024-10-17
creatine and Necrotizing Enterocolitis
creatine has been researched along with Necrotizing Enterocolitis in 1 studies
Research
Studies (1)
Timeframe | Studies, this research(%) | All Research% |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
Gawlowski, Z | 1 |
Aladangady, N | 1 |
Coen, PG | 1 |
Clinical Trials (1)
Trial Overview
Trial | Phase | Enrollment | Study Type | Start Date | Status |
Early Sodium Intake in Preterm Newborns; Randomized Clinical Trial[NCT04035564] | Phase 4 | 52 participants (Actual) | Interventional | 2018-03-30 | Completed |
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Trial Outcomes
% Weight Change
The difference between initial weight and 72hrs weight, expressed in percentage of birth weight. (NCT04035564)
Timeframe: Initial weight (baseline) vs 72 hours
Intervention | % of birth weight (Mean) |
---|
Sodium < 1mEq/kg/Day | -9.206 |
Sodium 5mEq/kg/Day | -6.345 |
Change in Serum Sodium
The difference between current serum sodium and initial serum sodium (NCT04035564)
Timeframe: Initial serum sodium (baseline) vs 72 hours
Intervention | mEq/L (Mean) |
---|
Sodium < 1mEq/kg/Day | 1.921 |
Sodium 5mEq/kg/Day | 5.71 |
Hypernatremia
serum sodium >150mEq/L (NCT04035564)
Timeframe: 72 hours
Intervention | Participants (Count of Participants) |
---|
Sodium < 1mEq/kg/Day | 1 |
Sodium 5mEq/kg/Day | 1 |
Hyponatremia
serum sodium <130mEq/L (NCT04035564)
Timeframe: 72 hours
Intervention | Participants (Count of Participants) |
---|
Sodium < 1mEq/kg/Day | 6 |
Sodium 5mEq/kg/Day | 1 |
Mortality
Death during hospitalization. (NCT04035564)
Timeframe: Patients will be followed during hospitalization, an expected average of 3 months of age
Intervention | Participants (Count of Participants) |
---|
Sodium < 1mEq/kg/Day | 5 |
Sodium 5mEq/kg/Day | 2 |
Number of Participants With Intraventricular Hemorrhage
Bleeding into the brainĀ“s ventricular system (intracranial ultrasound). (NCT04035564)
Timeframe: Patients will be followed during hospitalization, an expected average of 3 months of age
Intervention | Participants (Count of Participants) |
---|
Sodium < 1mEq/kg/Day | 6 |
Sodium 5mEq/kg/Day | 4 |
Number of Participants With Late-onset Sepsis
Positive blood culture and/or 5 days of continuous antimicrobial therapy (NCT04035564)
Timeframe: Patients will be followed during hospitalization, an expected average of 3 months of age
Intervention | Participants (Count of Participants) |
---|
Sodium < 1mEq/kg/Day | 8 |
Sodium 5mEq/kg/Day | 5 |
Number of Participants With Necrotizing Enterocolitis
"Number of patients with Bell stage II or greater necrotizing enterocolitis~Bell's Staging:~Stage II A:~Gastrointestinal signs: Increasing gastric aspirates, mild abdominal distention, fecal occult blood, absent bowel sounds.~Systemic signs: Temperature instability, apnea, bradycardia, lethargy. Radiological findings: Intestinal dilatation, ileus, pneumatosis intestinalis.~Stage II B:~Gastrointestinal signs: As stage IIA plus abdominal tenderness. Systemic signs: As stage IIA plus metabolic acidosis and thrombocytopenia. Radiological findings: As stage IIA plus portal vein gas and ascites.~Stage III A:~Gastrointestinal signs: As stage IIB plus marked abdominal tenderness and generalised peritonitis.~Systemic signs: As stage IIB plus hypotension and severe apnea. Radiological findings: As stage IIB~Stage III B:~Gastrointestinal signs: As stage IIIA As stage IIIA As stage IIIA plus pneumoperitoneum" (NCT04035564)
Timeframe: Patients will be followed during hospitalization, an expected average of 3 months of age
Intervention | Participants (Count of Participants) |
---|
Sodium < 1mEq/kg/Day | 2 |
Sodium 5mEq/kg/Day | 2 |
Weight Change
The difference between current weight and initial weight (NCT04035564)
Timeframe: Initial weight (baseline) vs 72 hours
Intervention | Grams (Mean) |
---|
Sodium < 1mEq/kg/Day | -135.43 |
Sodium 5mEq/kg/Day | -96.05 |
Other Studies
1 other study available for creatine and Necrotizing Enterocolitis