Page last updated: 2024-10-17

creatine and Myotonic Dystrophy

creatine has been researched along with Myotonic Dystrophy in 12 studies

Myotonic Dystrophy: Neuromuscular disorder characterized by PROGRESSIVE MUSCULAR ATROPHY; MYOTONIA, and various multisystem atrophies. Mild INTELLECTUAL DISABILITY may also occur. Abnormal TRINUCLEOTIDE REPEAT EXPANSION in the 3' UNTRANSLATED REGIONS of DMPK PROTEIN gene is associated with Myotonic Dystrophy 1. DNA REPEAT EXPANSION of zinc finger protein-9 gene intron is associated with Myotonic Dystrophy 2.

Research Excerpts

ExcerptRelevanceReference
"We assessed safety and efficacy of creatine monohydrate (Cr) in myotonic dystrophy (DM1) in a double-blind, cross-over trial."9.10Creatine monohydrate in myotonic dystrophy: a double-blind, placebo-controlled clinical study. ( Dunkl, E; Hautmann, H; Kohnen, R; Lochmüller, H; Müller-Felber, W; Pongratz, D; Reilich, P; Schlotter, B; Walter, MC, 2002)
"We assessed safety and efficacy of creatine monohydrate (Cr) in myotonic dystrophy (DM1) in a double-blind, cross-over trial."5.10Creatine monohydrate in myotonic dystrophy: a double-blind, placebo-controlled clinical study. ( Dunkl, E; Hautmann, H; Kohnen, R; Lochmüller, H; Müller-Felber, W; Pongratz, D; Reilich, P; Schlotter, B; Walter, MC, 2002)
" We measured 24 h 8-hydroxy-2'-deoxyguanosine (8-OHdG) excretion in 24 patients with MD (DMD + Becker's MD), 23 with myotonic dystrophy, and 34 healthy controls."3.72Patients with dystrophinopathy show evidence of increased oxidative stress. ( Rodriguez, MC; Tarnopolsky, MA, 2003)
"In patients with congenital myotonic dystrophy, the N-acetyl aspartate/choline ratio did not increase with advancing age, but the N-acetyl aspartate/creatine ratio did."1.29Proton magnetic resonance spectroscopy of brain in congenital myotonic dystrophy. ( Harada, M; Hashimoto, T; Kuroda, Y; Miyazaki, M; Miyoshi, H; Tanouchi, M; Tayama, M; Yoshimoto, T, 1995)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19904 (33.33)18.7374
1990's3 (25.00)18.2507
2000's4 (33.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Turner, C1
Hilton-Jones, D1
Walter, MC1
Reilich, P1
Lochmüller, H1
Kohnen, R1
Schlotter, B1
Hautmann, H1
Dunkl, E1
Pongratz, D1
Müller-Felber, W1
Rodriguez, MC1
Tarnopolsky, MA1
HARVEY, JC1
Tarnopolsky, M1
Mahoney, D1
Thompson, T1
Naylor, H1
Doherty, TJ1
Vielhaber, S1
Jakubiczka, S1
Gaul, C1
Schoenfeld, MA1
Debska-Vielhaber, G1
Zierz, S1
Heinze, HJ1
Niessen, HG1
Kaufmann, J1
Griggs, RC1
Moxley, RT1
Forbes, GB1
Hashimoto, T2
Tayama, M2
Yoshimoto, T2
Miyazaki, M2
Harada, M2
Miyoshi, H2
Tanouchi, M2
Kuroda, Y2
Akiguchi, I1
Nakano, S1
Shiino, A1
Kimura, R1
Inubushi, T1
Handa, J1
Nakamura, M1
Tanaka, M1
Oka, N1
Kimura, J1
Rowland, LP1
Emery, AE1
Burt, D1

Reviews

2 reviews available for creatine and Myotonic Dystrophy

ArticleYear
The myotonic dystrophies: diagnosis and management.
    Journal of neurology, neurosurgery, and psychiatry, 2010, Volume: 81, Issue:4

    Topics: Blotting, Southern; Chromosomes, Human, Pair 19; Creatine; Dehydroepiandrosterone; Diagnosis, Differ

2010
Muscular dystrophies.
    Disease-a-month : DM, 1972

    Topics: Alopecia; Creatine; Diagnosis, Differential; Electromyography; Eye Manifestations; Facial Paralysis;

1972

Trials

2 trials available for creatine and Myotonic Dystrophy

ArticleYear
Creatine monohydrate in myotonic dystrophy: a double-blind, placebo-controlled clinical study.
    Journal of neurology, 2002, Volume: 249, Issue:12

    Topics: Activities of Daily Living; Adult; Creatine; Cross-Over Studies; Double-Blind Method; Female; Humans

2002
Creatine monohydrate supplementation does not increase muscle strength, lean body mass, or muscle phosphocreatine in patients with myotonic dystrophy type 1.
    Muscle & nerve, 2004, Volume: 29, Issue:1

    Topics: Activities of Daily Living; Adult; Body Mass Index; Creatine; Cross-Over Studies; Exercise Tolerance

2004

Other Studies

8 other studies available for creatine and Myotonic Dystrophy

ArticleYear
Patients with dystrophinopathy show evidence of increased oxidative stress.
    Free radical biology & medicine, 2003, May-01, Volume: 34, Issue:9

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Biomarkers; Body Weight; Case-Control Studies; Child; Creatine;

2003
MYOTONIA DYSTROPHICA.
    Transactions of the American Clinical and Climatological Association, 1962, Volume: 74

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Cholecystokinin; Creatine; Creatinine; Deglutition Disorde

1962
Brain 1H magnetic resonance spectroscopic differences in myotonic dystrophy type 2 and type 1.
    Muscle & nerve, 2006, Volume: 34, Issue:2

    Topics: Adult; Aspartic Acid; Brain Chemistry; Cerebral Cortex; Choline; Creatine; Female; Humans; Magnetic

2006
3-methylhistidine excretion in myotonic dystrophy.
    Neurology, 1980, Volume: 30, Issue:12

    Topics: Adolescent; Adult; Child; Creatine; Creatinine; Diet; Histidine; Hospitalization; Humans; Male; Meat

1980
Proton magnetic resonance spectroscopy of brain in congenital myotonic dystrophy.
    Pediatric neurology, 1995, Volume: 12, Issue:4

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Case-Control Studies; Child; Child, Preschool; Choline; Cre

1995
[Proton MR spectroscopy of the brain in patients with congenital myotonic dystrophy].
    No to hattatsu = Brain and development, 1995, Volume: 27, Issue:3

    Topics: Adolescent; Aspartic Acid; Brain; Child; Child, Preschool; Choline; Creatine; Female; Humans; Infant

1995
Brain proton magnetic resonance spectroscopy and brain atrophy in myotonic dystrophy.
    Archives of neurology, 1999, Volume: 56, Issue:3

    Topics: Adolescent; Adult; Aspartic Acid; Atrophy; Case-Control Studies; Cerebral Cortex; Creatine; Female;

1999
Amino acid, creatine and creatinine studies in myotonic dystrophy.
    Clinica chimica acta; international journal of clinical chemistry, 1972, Volume: 39, Issue:2

    Topics: Adult; Age Factors; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Creatine; Creatin

1972