Page last updated: 2024-10-17

creatine and Muscular Atrophy

creatine has been researched along with Muscular Atrophy in 58 studies

Muscular Atrophy: Derangement in size and number of muscle fibers occurring with aging, reduction in blood supply, or following immobilization, prolonged weightlessness, malnutrition, and particularly in denervation.

Research Excerpts

ExcerptRelevanceReference
"Creatine is a generally well tolerated, low-cost, over-the-counter nutritional supplement that shows potential in improving lean body mass and functionality in patients with wasting diseases."8.85Can the use of creatine supplementation attenuate muscle loss in cachexia and wasting? ( Mulligan, K; Sakkas, GK; Schambelan, M, 2009)
"Gyrate atrophy of the choroid and retina is a disease characterized by progressive constriction of visual fields, a 10-fold to 20-fold elevation in plasma ornithine, and depressed activity of L-ornithine:2 oxoacid aminotransferase."7.66Supplementary creatine as a treatment for gyrate atrophy of the choroid and retina. ( Rapola, J; Simell, O; Sipilä, I; Vannas, A, 1981)
"Creatine is an endogenously produced metabolite, which has the theoretical potential to counteract many of the morphological and metabolic parameters underpinning sarcopenia."6.61Muscular Atrophy and Sarcopenia in the Elderly: Is There a Role for Creatine Supplementation? ( Artioli, GG; Dolan, E; Gualano, B; Pereira, RMR, 2019)
"Creatine was provided in drinking water for a total of 21 days."5.56Creatine supplementation in Walker-256 tumor-bearing rats prevents skeletal muscle atrophy by attenuating systemic inflammation and protein degradation signaling. ( Borges, FH; Cecchini, R; Cella, PS; Chimin, P; Deminice, R; Duarte, JA; Guarnier, FA; Guirro, PB; Marinello, PC; Ribeiro, DF; Testa, MTJ, 2020)
"Creatine is a generally well tolerated, low-cost, over-the-counter nutritional supplement that shows potential in improving lean body mass and functionality in patients with wasting diseases."4.85Can the use of creatine supplementation attenuate muscle loss in cachexia and wasting? ( Mulligan, K; Sakkas, GK; Schambelan, M, 2009)
" In patients, such myopathy is characterized by the gradual onset of proximal limb muscle weakness and a sudden increase in creatine excretion in 24h urine."4.80[The effect of corticotherapy on respiratory muscles]. ( Decramer, M; Gayan-Ramirez, G, 1998)
" Treatment with FS also prevented the dexamethasone-induced increase in serum creatine and creatine kinase levels, histopathological muscle fiber microvacuolation and fibrosis, and the immunoreactivity of muscle fibers for nitrotyrosine, 4-hydroxynonenal, inducible nitric oxide synthase and myostatin."3.81The administration of Fructus Schisandrae attenuates dexamethasone-induced muscle atrophy in mice. ( Choi, YH; Han, MH; Hwang, HJ; Kim, BW; Kim, CM; Kim, GY; Kim, JW; Kim, KY; Kim, SG; Ku, SK, 2015)
"We aimed to investigate the possible role of creatine (CR) supplementation in counteracting dexamethasone-induced muscle wasting and insulin resistance in rats."3.78Effects of creatine supplementation on muscle wasting and glucose homeostasis in rats treated with dexamethasone. ( Brum, PC; da Luz, CR; de Moraes, WM; de Salles Painelli, V; de Salvi Guimarães, F; dos Santos Costa, A; Gualano, B; Lancha, AH; Medeiros, A; Nicastro, H, 2012)
"Gyrate atrophy of the choroid and retina is a disease characterized by progressive constriction of visual fields, a 10-fold to 20-fold elevation in plasma ornithine, and depressed activity of L-ornithine:2 oxoacid aminotransferase."3.66Supplementary creatine as a treatment for gyrate atrophy of the choroid and retina. ( Rapola, J; Simell, O; Sipilä, I; Vannas, A, 1981)
"Creatine is an endogenously produced metabolite, which has the theoretical potential to counteract many of the morphological and metabolic parameters underpinning sarcopenia."2.61Muscular Atrophy and Sarcopenia in the Elderly: Is There a Role for Creatine Supplementation? ( Artioli, GG; Dolan, E; Gualano, B; Pereira, RMR, 2019)
"Creatine (Cr) is a naturally-occurring substance in the human body that plays a critical role in energy provision during muscle contraction."2.61The potential therapeutic effects of creatine supplementation on body composition and muscle function in cancer. ( Fairman, CM; Galvão, DA; Hart, NH; Kendall, KL; Newton, RU; Taaffe, DR, 2019)
"Muscle wasting during critical illness impairs recovery."2.52Impact of supplementation with amino acids or their metabolites on muscle wasting in patients with critical illness or other muscle wasting illness: a systematic review. ( Brett, SJ; Frost, G; Hickson, M; Wandrag, L, 2015)
"Creatine (Cr) is a nitrogenous organic acid and plays roles such as fast phosphate energy buffer to replenish ATP, osmolyte, antioxidant, neuromodulator, and as a compound with anabolic and ergogenic properties in muscle."1.72Creatine transporter-deficient rat model shows motor dysfunction, cerebellar alterations, and muscle creatine deficiency without muscle atrophy. ( Binz, PA; Braissant, O; Cudalbu, C; De Bock, K; Duran-Trio, L; Fernandes-Pires, G; Grosse, J; Roux-Petronelli, C; Sandi, C; Soro-Arnaiz, I, 2022)
"Creatine was provided in drinking water for a total of 21 days."1.56Creatine supplementation in Walker-256 tumor-bearing rats prevents skeletal muscle atrophy by attenuating systemic inflammation and protein degradation signaling. ( Borges, FH; Cecchini, R; Cella, PS; Chimin, P; Deminice, R; Duarte, JA; Guarnier, FA; Guirro, PB; Marinello, PC; Ribeiro, DF; Testa, MTJ, 2020)
"Creatine is a non-essential amino acid that is directly involved in the cross-bridge cycle providing a phosphate group to ADP during the initiation of muscle contraction."1.48High-fat diet suppresses the positive effect of creatine supplementation on skeletal muscle function by reducing protein expression of IGF-PI3K-AKT-mTOR pathway. ( Caldeira, EJ; Conte, M; Dos Santos, VC; Ferretti, R; Matsumura, CY; Mosqueira, M; Moura, EG; Pertille, A, 2018)
"Creatine (Cr) plays an important role in muscle energy homeostasis by its participation in the ATP-phosphocreatine phosphoryl exchange reaction mediated by creatine kinase."1.39Disturbed energy metabolism and muscular dystrophy caused by pure creatine deficiency are reversible by creatine intake. ( Choe, CU; Heerschap, A; Isbrandt, D; Kan, HE; Kemp, GJ; Matschke, J; Nabuurs, CI; Rodenburg, RJ; van Loon, LJ; Veltien, A; Wieringa, B, 2013)
"Furthermore, GW610742 initiated a muscle atrophy programme, possibly via changes in the Akt1/FOXO/MAFbx and MuRF1 signalling pathway."1.34PPARdelta agonism induces a change in fuel metabolism and activation of an atrophy programme, but does not impair mitochondrial function in rat skeletal muscle. ( Bennett, AJ; Constantin, D; Constantin-Teodosiu, D; Greenhaff, PL; Layfield, R; Tsintzas, K, 2007)
"In most mAG patients, muscle atrophy was accompanied by palmar erythema."1.29Biochemical and clinical study of muscle atrophy at thenar and hypothenar eminences in patients with cirrhosis. ( Iijima, T; Kaneko, K; Nambu, M, 1996)
" The progressive reduction of corticosteroid dosage led rapidly to a distinct improvement, but not to a remission, of symptoms."1.28Steroid myopathy: clinical and immunohistochemical study of a case. ( Camporeale, FS; Carandente, M; Cioffi, M; Gentile, A; Marolda, M; Orsini, AV; Palma, V, 1991)
"A thymoma was present in 17 patients."1.25Neurogenic muscle involvement in myasthenia gravis. A clinical and histopathological study. ( Bethlem, J; Oosterhuis, H, 1973)

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-199026 (44.83)18.7374
1990's4 (6.90)18.2507
2000's10 (17.24)29.6817
2010's13 (22.41)24.3611
2020's5 (8.62)2.80

Authors

AuthorsStudies
Duran-Trio, L1
Fernandes-Pires, G1
Grosse, J1
Soro-Arnaiz, I1
Roux-Petronelli, C1
Binz, PA1
De Bock, K1
Cudalbu, C1
Sandi, C1
Braissant, O1
Sun, M1
Jiao, H1
Wang, X1
Li, H1
Zhou, Y1
Zhao, J1
Lin, H1
Marzuca-Nassr, GN1
Fortes, MAS1
Guimarães-Ferreira, L1
Murata, GM1
Vitzel, KF1
Vasconcelos, DAA1
Bassit, RA1
Curi, R1
Dolan, E1
Artioli, GG1
Pereira, RMR1
Gualano, B2
Greif, DN1
Emerson, CP1
Allegra, P1
Arizpe, A1
Mansour, KL1
Cade, WH1
Baraga, MG1
Marshall, RN1
Smeuninx, B1
Morgan, PT1
Breen, L1
Ferretti, R1
Moura, EG1
Dos Santos, VC1
Caldeira, EJ1
Conte, M1
Matsumura, CY1
Pertille, A1
Mosqueira, M1
Valenzuela, PL1
Morales, JS1
Emanuele, E1
Pareja-Galeano, H1
Lucia, A1
Fairman, CM1
Kendall, KL1
Hart, NH1
Taaffe, DR1
Galvão, DA1
Newton, RU1
Cella, PS1
Marinello, PC1
Borges, FH1
Ribeiro, DF1
Chimin, P1
Testa, MTJ1
Guirro, PB1
Duarte, JA1
Cecchini, R1
Guarnier, FA1
Deminice, R1
Moon, A1
Heywood, L1
Rutherford, S1
Cobbold, C1
Wandrag, L1
Brett, SJ1
Frost, G1
Hickson, M1
Kim, JW1
Ku, SK1
Han, MH1
Kim, KY1
Kim, SG1
Kim, GY1
Hwang, HJ1
Kim, BW1
Kim, CM1
Choi, YH1
Hespel, P4
Derave, W3
Sakkas, GK1
Schambelan, M1
Mulligan, K1
Candow, DG1
Chilibeck, PD1
Nicastro, H1
de Moraes, WM1
de Salles Painelli, V1
da Luz, CR1
dos Santos Costa, A1
de Salvi Guimarães, F1
Medeiros, A1
Brum, PC1
Lancha, AH1
Stimpson, SA1
Turner, SM1
Clifton, LG1
Poole, JC1
Mohammed, HA1
Shearer, TW1
Waitt, GM1
Hagerty, LL1
Remlinger, KS1
Hellerstein, MK1
Evans, WJ1
Nabuurs, CI1
Choe, CU1
Veltien, A1
Kan, HE1
van Loon, LJ1
Rodenburg, RJ1
Matschke, J1
Wieringa, B1
Kemp, GJ1
Isbrandt, D1
Heerschap, A1
Snow, RJ1
Van Den Bosch, L1
Lemmens, G1
Eijnde, BO2
Robberecht, W1
VIGNOS, PJ1
WARNER, JL1
FITCH, CD2
SINTON, DW1
AOKI, I1
Aoki, MS1
Lima, WP1
Miyabara, EH1
Gouveia, CH1
Moriscot, AS1
CASPE, S1
DAVIDSON, B1
TRUHLAR, J1
Ramaekers, M1
Menezes, LG1
Sobreira, C1
Neder, L1
Rodrigues-Júnior, AL1
Martinez, JA1
Constantin, D1
Constantin-Teodosiu, D1
Layfield, R1
Tsintzas, K1
Bennett, AJ1
Greenhaff, PL2
Kley, RA1
Tarnopolsky, MA2
Vorgerd, M1
Safdar, A1
Saiki, S1
Lemieux, G1
Neemeh, JA1
Brautbar, N1
Sipilä, I1
Rapola, J1
Simell, O1
Vannas, A1
Il'ina, NA2
Antipova, RI1
Khokhlov, AP2
Nambu, M1
Kaneko, K1
Iijima, T1
Gayan-Ramirez, G1
Decramer, M1
Kanda, F1
Takatani, K1
Okuda, S1
Matsushita, T1
Chihara, K1
Op 't Eijnde, B1
Ursø, B1
Richter, EA1
Poliakova, NF1
Bernhardt, W4
Marolda, M1
Palma, V1
Camporeale, FS1
Carandente, M1
Cioffi, M1
Orsini, AV1
Gentile, A1
Broyer, M1
Delaporte, C1
Maziere, B1
Koufen, H1
Consbruch, U1
Eickhoff, W1
Oosterhuis, H1
Bethlem, J1
Tomlinson, BE1
Walton, JN1
Irving, D1
Heyck, H1
Frey, JR1
Kaeser, HE1
Krause, R1
Bauman, MB1
DiMase, JD1
Oski, F1
Senior, JR1
Frame, B1
Heinze, EG1
Block, MA1
Manson, GA1
Medsger, TA1
Rodnan, GP1
Moossy, J1
Vester, JW1
Lucy, DD1
Bornhofen, JH1
Dalrymple, GV1
Saunders, JF1
Szczepski, O1
Mietkiewski, K1
Pawlaczyk, B1
Lukaszyk, A1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Creatine Supplementation and Resistance Training in Patients With Breast Cancer (CaRTiC Study)[NCT05878106]120 participants (Anticipated)Interventional2024-01-08Not yet recruiting
A Comparison of Aerobic and Resistance Exercise for Counteracting the Adverse Effects of Androgen Deprivation Therapy in Men With Prostate Cancer[NCT05156424]Phase 1/Phase 224 participants (Anticipated)Interventional2021-09-09Recruiting
Effect of a Power/Resistance Exercise Program and Oral Supplementation With Beta-hydroxy-beta-methyl Butyrate (HMB) on the Muscle Quality Index in Older Adults. A Randomized Controlled Trial[NCT04734951]76 participants (Anticipated)Interventional2023-06-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

14 reviews available for creatine and Muscular Atrophy

ArticleYear
Muscular Atrophy and Sarcopenia in the Elderly: Is There a Role for Creatine Supplementation?
    Biomolecules, 2019, 10-23, Volume: 9, Issue:11

    Topics: Aged; Aging; Animals; Creatine; Dietary Supplements; Exercise; Humans; Muscular Atrophy

2019
Supplement Use in Patients Undergoing Anterior Cruciate Ligament Reconstruction: A Systematic Review.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2020, Volume: 36, Issue:9

    Topics: Anterior Cruciate Ligament Injuries; Anterior Cruciate Ligament Reconstruction; Ascorbic Acid; Creat

2020
Nutritional Strategies to Offset Disuse-Induced Skeletal Muscle Atrophy and Anabolic Resistance in Older Adults: From Whole-Foods to Isolated Ingredients.
    Nutrients, 2020, May-25, Volume: 12, Issue:5

    Topics: Aged; Aging; Creatine; Diet, High-Protein; Dietary Proteins; Dietary Supplements; Exercise; Fatty Ac

2020
Supplements with purported effects on muscle mass and strength.
    European journal of nutrition, 2019, Volume: 58, Issue:8

    Topics: Caffeine; Creatine; Dietary Supplements; Fatty Acids, Unsaturated; Humans; Muscle Strength; Muscle,

2019
The potential therapeutic effects of creatine supplementation on body composition and muscle function in cancer.
    Critical reviews in oncology/hematology, 2019, Volume: 133

    Topics: Body Composition; Creatine; Dietary Supplements; Exercise; Humans; Muscle Strength; Muscle, Skeletal

2019
Creatine supplementation: can it improve quality of life in the elderly without associated resistance training?
    Current aging science, 2013, Volume: 6, Issue:3

    Topics: Activities of Daily Living; Age Factors; Aged; Aging; Anabolic Agents; Creatine; Dietary Supplements

2013
Impact of supplementation with amino acids or their metabolites on muscle wasting in patients with critical illness or other muscle wasting illness: a systematic review.
    Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2015, Volume: 28, Issue:4

    Topics: Aged; Amino Acids; Amino Acids, Essential; Body Composition; Creatine; Critical Illness; Diet; Dieta

2015
Ergogenic effects of creatine in sports and rehabilitation.
    Sub-cellular biochemistry, 2007, Volume: 46

    Topics: Administration, Oral; Anabolic Agents; Athletic Performance; Creatine; Exercise; Gene Expression Reg

2007
Can the use of creatine supplementation attenuate muscle loss in cachexia and wasting?
    Current opinion in clinical nutrition and metabolic care, 2009, Volume: 12, Issue:6

    Topics: Adenosine Triphosphate; Body Composition; Cachexia; Creatine; Dietary Supplements; Exercise; Humans;

2009
Potential of creatine supplementation for improving aging bone health.
    The journal of nutrition, health & aging, 2010, Volume: 14, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Bone Density; Creatine; Dietary Supplements; Female; Humans; Male; M

2010
Creatine treatment in muscle disorders: a meta-analysis of randomised controlled trials.
    Journal of neurology, neurosurgery, and psychiatry, 2008, Volume: 79, Issue:4

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Creatine; Dose-Response Relationship, Drug; Energy

2008
The potential benefits of creatine and conjugated linoleic acid as adjuncts to resistance training in older adults.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2008, Volume: 33, Issue:1

    Topics: Aged; Aging; Creatine; Exercise; Humans; Linoleic Acids, Conjugated; Muscular Atrophy; Physical Fitn

2008
Skeletal myopathy in uremia: abnormal energy metabolism.
    Kidney international. Supplement, 1983, Volume: 16

    Topics: Actomyosin; Adenosine Triphosphate; Animals; Cell Membrane; Creatine; Creatine Kinase; Energy Metabo

1983
[The effect of corticotherapy on respiratory muscles].
    Revue des maladies respiratoires, 1998, Volume: 15, Issue:1

    Topics: Adrenal Cortex Hormones; Aminoglycosides; Animals; Anti-Bacterial Agents; Chronic Disease; Clinical

1998

Trials

1 trial available for creatine and Muscular Atrophy

ArticleYear
Effect of oral creatine supplementation on human muscle GLUT4 protein content after immobilization.
    Diabetes, 2001, Volume: 50, Issue:1

    Topics: Administration, Oral; Adult; Casts, Surgical; Creatine; Double-Blind Method; Female; Glucose Transpo

2001

Other Studies

43 other studies available for creatine and Muscular Atrophy

ArticleYear
Creatine transporter-deficient rat model shows motor dysfunction, cerebellar alterations, and muscle creatine deficiency without muscle atrophy.
    Journal of inherited metabolic disease, 2022, Volume: 45, Issue:2

    Topics: Animals; Cerebellar Diseases; Cerebellum; Creatine; Guanidinoacetate N-Methyltransferase; Humans; Me

2022
The regulating pathway of creatine on muscular protein metabolism depends on the energy state.
    American journal of physiology. Cell physiology, 2022, 05-01, Volume: 322, Issue:5

    Topics: Animals; Chickens; Creatine; Energy Metabolism; Glucose; Muscle, Skeletal; Muscular Atrophy; Muscula

2022
Short-term creatine supplementation changes protein metabolism signaling in hindlimb suspension.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2019, Volume: 52, Issue:10

    Topics: Animals; Creatine; Dietary Supplements; Disease Models, Animal; Hindlimb Suspension; Male; Muscle, S

2019
High-fat diet suppresses the positive effect of creatine supplementation on skeletal muscle function by reducing protein expression of IGF-PI3K-AKT-mTOR pathway.
    PloS one, 2018, Volume: 13, Issue:10

    Topics: Adenosine Diphosphate; Animals; Antioxidants; Creatine; Diet, High-Fat; Dietary Supplements; Inflamm

2018
Creatine supplementation in Walker-256 tumor-bearing rats prevents skeletal muscle atrophy by attenuating systemic inflammation and protein degradation signaling.
    European journal of nutrition, 2020, Volume: 59, Issue:2

    Topics: Animals; Carcinoma 256, Walker; Creatine; Dietary Supplements; Disease Models, Animal; Inflammation;

2020
The administration of Fructus Schisandrae attenuates dexamethasone-induced muscle atrophy in mice.
    International journal of molecular medicine, 2015, Volume: 36, Issue:1

    Topics: Aldehydes; Animals; Anti-Inflammatory Agents; Antioxidants; Creatine; Creatine Kinase; Dexamethasone

2015
Effects of creatine supplementation on muscle wasting and glucose homeostasis in rats treated with dexamethasone.
    Amino acids, 2012, Volume: 42, Issue:5

    Topics: Animals; Blood Glucose; Creatine; Dexamethasone; Drinking Water; Glucose Transporter Type 4; Humans;

2012
Total-body creatine pool size and skeletal muscle mass determination by creatine-(methyl-D3) dilution in rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:11

    Topics: Animals; Creatine; Male; Metabolic Clearance Rate; Methylation; Muscle, Skeletal; Muscular Atrophy;

2012
Disturbed energy metabolism and muscular dystrophy caused by pure creatine deficiency are reversible by creatine intake.
    The Journal of physiology, 2013, Jan-15, Volume: 591, Issue:2

    Topics: Adenosine Triphosphate; Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Animals; Creatine

2013
AGAT knockout mice provide an opportunity to titrate tissue creatine content.
    The Journal of physiology, 2013, Jan-15, Volume: 591, Issue:2

    Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Animals; Creatine; Developmental Disabili

2013
Skeletal muscle properties in a transgenic mouse model for amyotrophic lateral sclerosis: effects of creatine treatment.
    Neurobiology of disease, 2003, Volume: 13, Issue:3

    Topics: Adenosine Triphosphate; Amyotrophic Lateral Sclerosis; Animals; Body Weight; Creatine; Glycogen; Hum

2003
GLYCOGEN, CREATINE, AND HIGH ENERGY PHOSPHATE IN HUMAN MUSCLE DISEASE.
    The Journal of laboratory and clinical medicine, 1963, Volume: 62

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Adolescent; Blood Chemical Analysis; Child; Coenzymes;

1963
A STUDY OF CREATINE METABOLISM IN DISEASES CAUSING MUSCLE WASTING.
    The Journal of clinical investigation, 1964, Volume: 43

    Topics: Black People; Carbon Isotopes; Creatine; Creatinine; Metabolism; Muscular Atrophy; Muscular Dystroph

1964
[CLINICAL AND PATHOLOGIC STUDIES IN THYROTOXIC MYOPATHY].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1963, Nov-10, Volume: 52

    Topics: Adolescent; Basal Metabolism; Child; Chlorides; Creatine; Creatinine; Endocrine System Diseases; Hum

1963
Deleteriuos effects of immobilization upon rat skeletal muscle: role of creatine supplementation.
    Clinical nutrition (Edinburgh, Scotland), 2004, Volume: 23, Issue:5

    Topics: Administration, Oral; Animals; Creatine; Hindlimb Suspension; Male; Muscle Fibers, Fast-Twitch; Musc

2004
Creatine-creatinine indices of diabetic subjects and effect of muscular degeneration.
    The American journal of physiology, 1949, Volume: 159, Issue:3

    Topics: Blood; Creatine; Creatinine; Diabetes Mellitus; Humans; Muscles; Muscular Atrophy

1949
No effects of lifelong creatine supplementation on sarcopenia in senescence-accelerated mice (SAMP8).
    American journal of physiology. Endocrinology and metabolism, 2005, Volume: 289, Issue:2

    Topics: Aging; Animals; Creatine; Dietary Supplements; Energy Metabolism; Male; Mice; Mice, Inbred Strains;

2005
Creatine supplementation attenuates corticosteroid-induced muscle wasting and impairment of exercise performance in rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2007, Volume: 102, Issue:2

    Topics: Adrenal Cortex Hormones; Animals; Body Weight; Creatine; Dexamethasone; Diaphragm; Dose-Response Rel

2007
PPARdelta agonism induces a change in fuel metabolism and activation of an atrophy programme, but does not impair mitochondrial function in rat skeletal muscle.
    The Journal of physiology, 2007, Aug-15, Volume: 583, Issue:Pt 1

    Topics: Adenosine Triphosphate; Animals; Creatine; DNA; Energy Metabolism; Lactates; Male; Mitochondria, Mus

2007
[Clinical and experimental studies on Cushing's syndrome and steroid myopathy. 2. Experimental study].
    Nihon Naibunpi Gakkai zasshi, 1966, Oct-20, Volume: 42, Issue:7

    Topics: Adenosine Triphosphate; Animals; Body Weight; Cortisone; Creatine; Creatine Kinase; Diuresis; Fructo

1966
Charcot-Marie-Tooth disease and nephritis.
    Canadian Medical Association journal, 1967, Nov-11, Volume: 97, Issue:20

    Topics: Adult; Blood Pressure; Blood Urea Nitrogen; Creatine; Creatinine; Female; Hand Deformities, Acquired

1967
Supplementary creatine as a treatment for gyrate atrophy of the choroid and retina.
    The New England journal of medicine, 1981, Apr-09, Volume: 304, Issue:15

    Topics: Administration, Oral; Adolescent; Adult; Atrophy; Child; Choroid; Constriction, Pathologic; Creatine

1981
[Use of lithium carbonate to treat Kugelberg--Welander spinal amyotrophy].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1980, Volume: 80, Issue:11

    Topics: Adolescent; Adult; Carbonates; Child; Creatine; Creatinine; Female; Humans; Lithium; Male; Motor Neu

1980
Biochemical and clinical study of muscle atrophy at thenar and hypothenar eminences in patients with cirrhosis.
    Liver, 1996, Volume: 16, Issue:1

    Topics: Aged; Alanine Transaminase; Creatine; Creatinine; Electrolytes; Estradiol; Estriol; Estrone; Female;

1996
Preventive effects of insulinlike growth factor-I on steroid-induced muscle atrophy.
    Muscle & nerve, 1999, Volume: 22, Issue:2

    Topics: Animals; Body Weight; Creatine; Creatinine; Dose-Response Relationship, Drug; Female; Glucocorticoid

1999
[Pathogenesis of creatinuria and aminoaciduria in neuromuscular diseases].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1977, Volume: 77, Issue:7

    Topics: Adolescent; Adult; Amino Acids; Amyotrophic Lateral Sclerosis; Caffeine; Child; Child, Preschool; Cr

1977
[Diagnostic and therapeutic decisions in metabolic/toxic neurogenic leading symptoms of internal diseases].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1976, Volume: 82 Pt 1

    Topics: Adult; Amyotrophic Lateral Sclerosis; Creatine; Female; Galactose; Humans; Insulin; Insulin Secretio

1976
Steroid myopathy: clinical and immunohistochemical study of a case.
    Italian journal of neurological sciences, 1991, Volume: 12, Issue:4

    Topics: Adult; Creatine; Electromyography; Female; Foot Diseases; Humans; Muscle Hypotonia; Muscular Atrophy

1991
[Clinical observations on the significance of increased creatine excretion].
    Zeitschrift fur Neurologie, 1972, Dec-29, Volume: 203, Issue:3

    Topics: Acute Disease; Chronic Disease; Creatine; Creatine Kinase; Humans; Muscles; Muscular Atrophy; Muscul

1972
Water, electrolytes and protein content of muscle obtained by needle biopsy in uremic children.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1974, Jun-10, Volume: 21, Issue:6

    Topics: Adolescent; Biopsy, Needle; Blood Pressure; Child; Child, Preschool; Chlorine; Creatine; Extracellul

1974
[Creatine excretion as a criterion in neurological diagnosis].
    Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete, 1972, Volume: 40, Issue:7

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Creatine; Fear; Female; Humans; Male; Mental Disor

1972
[Prognosis in neurogenic and myogenic paresis: the aid of laboratory findings (author's transl)].
    Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete, 1974, Volume: 42, Issue:8

    Topics: Creatine; Electromyography; Humans; Muscular Atrophy; Muscular Diseases; Nervous System Diseases; Pa

1974
[Studies on the regulation of creatine synthesis in man].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1972, Volume: 353, Issue:10

    Topics: Animals; Chickens; Creatine; Ducks; Hexosyltransferases; Humans; Liver; Muscular Atrophy; Neoplasms;

1972
Neurogenic muscle involvement in myasthenia gravis. A clinical and histopathological study.
    Journal of neurology, neurosurgery, and psychiatry, 1973, Volume: 36, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Creatine; Creatine Kinase; Electromyography; Facial Muscles; Female;

1973
Spinal cord limb motor neurones in muscular dystrophy.
    Journal of the neurological sciences, 1974, Volume: 22, Issue:3

    Topics: Adolescent; Adult; Autoantibodies; Autopsy; Creatine; Diagnostic Errors; Electrocardiography; Electr

1974
[Progressive muscular diseases--clinical picture, pathophysiology, and differential diagnosis].
    Deutsches medizinisches Journal, 1971, Volume: 22, Issue:12

    Topics: Biopsy; Child; Creatine; Diagnosis, Differential; Electromyography; Female; Heterozygote; Humans; Ma

1971
Therapeutic trials with an anabolic steroid and hexahydrocoenzyme Q4 in a case of spinal muscular atrophy.
    European neurology, 1970, Volume: 3, Issue:5

    Topics: Creatine; Creatinine; Humans; Male; Middle Aged; Muscular Atrophy; Spinal Cord Diseases

1970
Brown bowel and skeletal myopathy associated with vitamin E depletion in pancreatic insufficiency.
    Gastroenterology, 1968, Volume: 54, Issue:1

    Topics: Celiac Disease; Creatine; Folic Acid; Humans; Intestine, Small; Male; Malonates; Middle Aged; Muscle

1968
Myopathy in primary hyperparathyroidism. Observations in three patients.
    Annals of internal medicine, 1968, Volume: 68, Issue:5

    Topics: Adenoma; Calcium; Child; Creatine; Creatinine; Electromyography; Female; Humans; Hyperparathyroidism

1968
Skeletal muscle involvement in progressive systemic sclerosis (scleroderma).
    Arthritis and rheumatism, 1968, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Aged; Aspartate Aminotransferases; Body Weight; Creatine; Creatine Kinase; Creati

1968
Creatine metabolism in skeletal muscle. II. creatine kinetics in man.
    Neurology, 1968, Volume: 18, Issue:1 Pt 1

    Topics: Adult; Carbon Isotopes; Child; Child, Preschool; Creatine; Creatinine; Female; Humans; Kinetics; Mal

1968
Biochemical dimensions of space biology.
    Space life sciences, 1968, Volume: 1, Issue:1

    Topics: Animals; Avitaminosis; Bone Diseases; Creatine; Creatinine; Extraterrestrial Environment; Humans; Mo

1968
[A contribution to the clinical and histological picture of progressive hemiatrophy].
    Pediatria polska, 1969, Volume: 44, Issue:2

    Topics: Body Temperature; Child, Preschool; Creatine; Creatinine; Female; Histocytochemistry; Humans; Muscle

1969