creatine has been researched along with Muscle Weakness in 18 studies
Muscle Weakness: A vague complaint of debility, fatigue, or exhaustion attributable to weakness of various muscles. The weakness can be characterized as subacute or chronic, often progressive, and is a manifestation of many muscle and neuromuscular diseases. (From Wyngaarden et al., Cecil Textbook of Medicine, 19th ed, p2251)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test the hypothesis that oral creatine supplements with exercise are more effective than exercise alone in improving muscle function in patients with established dermatomyositis or polymyositis receiving chronic medical therapies who are clinically weak yet stable." | 9.12 | Creatine supplements in patients with idiopathic inflammatory myopathies who are clinically weak after conventional pharmacologic treatment: Six-month, double-blind, randomized, placebo-controlled trial. ( Alexanderson, H; Bell, JD; Chung, YL; Dastmalchi, M; Hamilton, G; Lundberg, IE; Morrison, C; Pipitone, N; Richards, S; Scott, DL; Ståhl-Hallengren, C; Thomas, EL, 2007) |
| "We assessed safety and efficacy of creatine monohydrate (Cr) in myotonic dystrophy (DM1) in a double-blind, cross-over trial." | 9.10 | Creatine monohydrate in myotonic dystrophy: a double-blind, placebo-controlled clinical study. ( Dunkl, E; Hautmann, H; Kohnen, R; Lochmüller, H; Müller-Felber, W; Pongratz, D; Reilich, P; Schlotter, B; Walter, MC, 2002) |
| "Creatine did not enhance muscle power in knee extension (p = 0." | 6.73 | Effect of creatine supplementation on muscle capacity in individuals with multiple sclerosis. ( Cotugna, N; Fang, CS; Malin, SK, 2008) |
| "To test the hypothesis that oral creatine supplements with exercise are more effective than exercise alone in improving muscle function in patients with established dermatomyositis or polymyositis receiving chronic medical therapies who are clinically weak yet stable." | 5.12 | Creatine supplements in patients with idiopathic inflammatory myopathies who are clinically weak after conventional pharmacologic treatment: Six-month, double-blind, randomized, placebo-controlled trial. ( Alexanderson, H; Bell, JD; Chung, YL; Dastmalchi, M; Hamilton, G; Lundberg, IE; Morrison, C; Pipitone, N; Richards, S; Scott, DL; Ståhl-Hallengren, C; Thomas, EL, 2007) |
| "We assessed safety and efficacy of creatine monohydrate (Cr) in myotonic dystrophy (DM1) in a double-blind, cross-over trial." | 5.10 | Creatine monohydrate in myotonic dystrophy: a double-blind, placebo-controlled clinical study. ( Dunkl, E; Hautmann, H; Kohnen, R; Lochmüller, H; Müller-Felber, W; Pongratz, D; Reilich, P; Schlotter, B; Walter, MC, 2002) |
| " In patients, such myopathy is characterized by the gradual onset of proximal limb muscle weakness and a sudden increase in creatine excretion in 24h urine." | 4.80 | [The effect of corticotherapy on respiratory muscles]. ( Decramer, M; Gayan-Ramirez, G, 1998) |
| "Creatine monohydrate given orally led to a long-lasting improvement of muscular weakness and ataxia in a girl with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency." | 3.72 | Striking improvement of muscle strength under creatine therapy in a patient with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency. ( Hanefeld, F; Korenke, GC; Wanders, RJ, 2003) |
| "Creatine did not enhance muscle power in knee extension (p = 0." | 2.73 | Effect of creatine supplementation on muscle capacity in individuals with multiple sclerosis. ( Cotugna, N; Fang, CS; Malin, SK, 2008) |
| "Outpatients with tetraplegia and mild wrist extensor weakness were randomized to receive either creatine or placebo in a double-blind crossover design." | 2.71 | Creatine supplementation for weak muscles in persons with chronic tetraplegia: a randomized double-blind placebo-controlled crossover trial. ( Burns, SP; Frost, R; Jacquemin, G; Kendall, RW, 2005) |
| "We investigated and reported toxic hepatitis in 20 male athletes following self-prescribing of a number of dietary supplements which are lesser known." | 1.38 | Toxic hepatitis in a group of 20 male body-builders taking dietary supplements. ( Aryan, E; Balali-Mood, M; Riahi-Zanjani, B; Sadeghi, M; Timcheh-Hariri, A, 2012) |
| "Acquired diffuse paresis in an intensive care unit (ICU) can result from critical illness myopathy or polyneuropathy." | 1.33 | Origin of ICU acquired paresis determined by direct muscle stimulation. ( Brochard, L; Lefaucheur, JP; Nordine, T; Rodriguez, P, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.56) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 12 (66.67) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Schilling, E | 1 |
| Böhmer, F | 1 |
| Fritzsche, C | 1 |
| Weitzel, LR | 1 |
| Sandoval, PA | 1 |
| Mayles, WJ | 1 |
| Wischmeyer, PE | 1 |
| Shewmon, DA | 1 |
| Craig, JM | 1 |
| Chauhan, NS | 1 |
| Sharma, YP | 1 |
| Malin, SK | 1 |
| Cotugna, N | 1 |
| Fang, CS | 1 |
| Timcheh-Hariri, A | 1 |
| Balali-Mood, M | 1 |
| Aryan, E | 1 |
| Sadeghi, M | 1 |
| Riahi-Zanjani, B | 1 |
| Walter, MC | 1 |
| Reilich, P | 1 |
| Lochmüller, H | 1 |
| Kohnen, R | 1 |
| Schlotter, B | 1 |
| Hautmann, H | 1 |
| Dunkl, E | 1 |
| Pongratz, D | 1 |
| Müller-Felber, W | 1 |
| Schneider-Gold, C | 1 |
| Beck, M | 1 |
| Wessig, C | 1 |
| George, A | 1 |
| Kele, H | 1 |
| Reiners, K | 1 |
| Toyka, KV | 1 |
| Korenke, GC | 1 |
| Wanders, RJ | 1 |
| Hanefeld, F | 1 |
| FITCH, CD | 1 |
| DINNING, JS | 1 |
| Tarnopolsky, M | 1 |
| Mahoney, D | 1 |
| Thompson, T | 1 |
| Naylor, H | 1 |
| Doherty, TJ | 1 |
| Tyler, TF | 1 |
| Nicholas, SJ | 1 |
| Hershman, EB | 1 |
| Glace, BW | 1 |
| Mullaney, MJ | 1 |
| McHugh, MP | 1 |
| Kendall, RW | 1 |
| Jacquemin, G | 1 |
| Frost, R | 1 |
| Burns, SP | 1 |
| Lefaucheur, JP | 1 |
| Nordine, T | 1 |
| Rodriguez, P | 1 |
| Brochard, L | 1 |
| Chung, YL | 1 |
| Alexanderson, H | 1 |
| Pipitone, N | 1 |
| Morrison, C | 1 |
| Dastmalchi, M | 1 |
| Ståhl-Hallengren, C | 1 |
| Richards, S | 1 |
| Thomas, EL | 1 |
| Hamilton, G | 1 |
| Bell, JD | 1 |
| Lundberg, IE | 1 |
| Scott, DL | 1 |
| Gayan-Ramirez, G | 1 |
| Decramer, M | 1 |
| Willer, B | 1 |
| Stucki, G | 1 |
| Hoppeler, H | 1 |
| Brühlmann, P | 1 |
| Krähenbühl, S | 1 |
| Mazzini, L | 1 |
| Balzarini, C | 1 |
| Colombo, R | 1 |
| Mora, G | 1 |
| Pastore, I | 1 |
| De Ambrogio, R | 1 |
| Caligari, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Can Creatine Supplementation Improve Body Composition and Physical Function in Rheumatoid Arthritis Patients? A Randomised Controlled Pilot Trial[NCT01767844] | 43 participants (Actual) | Interventional | 2013-01-31 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for creatine and Muscle Weakness
| Article | Year |
|---|---|
Performance-enhancing sports supplements: role in critical care.
Topics: Amino Acids, Branched-Chain; Anabolic Agents; Androgens; Arginine; Creatine; Critical Care; Critical | 2009 |
[The effect of corticotherapy on respiratory muscles].
Topics: Adrenal Cortex Hormones; Aminoglycosides; Animals; Anti-Bacterial Agents; Chronic Disease; Clinical | 1998 |
9 trials available for creatine and Muscle Weakness
| Article | Year |
|---|---|
Effect of creatine supplementation on muscle capacity in individuals with multiple sclerosis.
Topics: Adult; Creatine; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Drug Administration S | 2008 |
Creatine monohydrate in myotonic dystrophy: a double-blind, placebo-controlled clinical study.
Topics: Activities of Daily Living; Adult; Creatine; Cross-Over Studies; Double-Blind Method; Female; Humans | 2002 |
Creatine monohydrate in DM2/PROMM: a double-blind placebo-controlled clinical study. Proximal myotonic myopathy.
Topics: Adult; Aged; Creatine; Dietary Supplements; Double-Blind Method; Female; Hand Strength; Humans; Male | 2003 |
Creatine monohydrate supplementation does not increase muscle strength, lean body mass, or muscle phosphocreatine in patients with myotonic dystrophy type 1.
Topics: Activities of Daily Living; Adult; Body Mass Index; Creatine; Cross-Over Studies; Exercise Tolerance | 2004 |
The effect of creatine supplementation on strength recovery after anterior cruciate ligament (ACL) reconstruction: a randomized, placebo-controlled, double-blind trial.
Topics: Administration, Oral; Adult; Anterior Cruciate Ligament; Anterior Cruciate Ligament Injuries; Atroph | 2004 |
Creatine supplementation for weak muscles in persons with chronic tetraplegia: a randomized double-blind placebo-controlled crossover trial.
Topics: Cervical Vertebrae; Chronic Disease; Creatine; Cross-Over Studies; Double-Blind Method; Female; Hand | 2005 |
Creatine supplements in patients with idiopathic inflammatory myopathies who are clinically weak after conventional pharmacologic treatment: Six-month, double-blind, randomized, placebo-controlled trial.
Topics: Administration, Oral; Creatine; Double-Blind Method; Energy Metabolism; Exercise; Female; Humans; Ma | 2007 |
Effects of creatine supplementation on muscle weakness in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Creatine; Disability Evaluation; Female; Health Status; Humans; | 2000 |
Effects of creatine supplementation on exercise performance and muscular strength in amyotrophic lateral sclerosis: preliminary results.
Topics: Administration, Oral; Adult; Aged; Amyotrophic Lateral Sclerosis; Arm; Body Mass Index; Creatine; Di | 2001 |
7 other studies available for creatine and Muscle Weakness
| Article | Year |
|---|---|
[20-year-old man with adynamia and syncopes].
Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Animals; Creatine; Diagnosis, Differential; Huma | 2020 |
Creatine supplementation prevents statin-induced muscle toxicity.
Topics: Creatine; Dietary Supplements; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Muscle Cramp; | 2010 |
A child with skin nodules and extensive soft tissue calcification.
Topics: Arm; Calcinosis; Child; Creatine; Dermatomyositis; Diagnosis, Differential; Fructose-Bisphosphate Al | 2012 |
Toxic hepatitis in a group of 20 male body-builders taking dietary supplements.
Topics: Adult; Amino Acids; Chemical and Drug Induced Liver Injury; Creatine; Dietary Supplements; Doping in | 2012 |
Striking improvement of muscle strength under creatine therapy in a patient with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Child; Creatine; Female; Humans; Lipid Metabolism, Inborn Errors; | 2003 |
Production of muscular weakness in rats by a creatine analogue.
Topics: Animals; Creatine; Creatinine; Muscle Weakness; Muscular Dystrophies; Organic Chemicals; Rats | 1960 |
Origin of ICU acquired paresis determined by direct muscle stimulation.
Topics: Adolescent; Adult; Child; Child, Preschool; Creatine; Diagnosis, Differential; Electric Stimulation; | 2006 |