Page last updated: 2024-10-17

creatine and Meningioma

creatine has been researched along with Meningioma in 30 studies

Meningioma: A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7)

Research Excerpts

ExcerptRelevanceReference
"While alanine is a relatively unique marker for meningioma, our results support the hypothesis that the combination of glutamate/creatine ratios and alanine on proton MRS is more specific and reliable for the diagnosis of meningiomas than alanine alone."9.12Utilization of glutamate/creatine ratios for proton spectroscopic diagnosis of meningiomas. ( Hazany, S; Healy, JF; Hesselink, JR; Imbesi, SG, 2007)
"While alanine is a relatively unique marker for meningioma, our results support the hypothesis that the combination of glutamate/creatine ratios and alanine on proton MRS is more specific and reliable for the diagnosis of meningiomas than alanine alone."5.12Utilization of glutamate/creatine ratios for proton spectroscopic diagnosis of meningiomas. ( Hazany, S; Healy, JF; Hesselink, JR; Imbesi, SG, 2007)
"The absolute concentrations of total alanine and creatine were decreased in high-grade compared with low-grade meningiomas, as was the ratio of glycine to alanine (all p < 0."3.76Using ex vivo proton magnetic resonance spectroscopy to reveal associations between biochemical and biological features of meningiomas. ( Coons, SW; Nieman, RA; Pfisterer, WK; Preul, MC; Scheck, AC; Spetzler, RF, 2010)
" MRS of normal brain parenchyma displays 4 main metabolites: N-acetyl aspartate (neuronal marker), creatine (cellular density marker), choline (membrane activity marker) and myoinositol (glial marker); pathological processes lead to variations of the level of these metabolites and/or the appearance of abnormal metabolites (lactate), following different patterns according to pathological process involved: glioma, meningioma, metastasis, bacterial or toxoplasmic abscess, radionecrosis."3.71[Contribution of magnetic resonance spectrometry to the diagnosis of intracranial tumors]. ( Confort-Gouny, S; Cozzone, PJ; Dufour, H; Galanaud, D; Le Fur, Y; Nicoli, F; Peragut, JC; Ranjeva, JP; Roche, P; Viout, P, 2002)
" All high-grade gliomas (n = 37) showed high choline and low or absent N-acetyl-L-aspartate and creatine along with lipid and/or lactate, whereas low-grade gliomas (n = 23) were characterized by low N-acetyl-aspartate and creatine and high choline and presence of only lactate."3.69Characterization of intracranial mass lesions with in vivo proton MR spectroscopy. ( Chhabra, DK; Gupta, RK; Jain, VK; Pandey, R; Poptani, H; Roy, R, 1995)
" The NAA (N-acetylaspartate)/Cho (choline) ratio of Grade 2 astrocytoma was higher than that of Grade 4."3.69Non-invasive characterization of brain tumor by in-vivo proton magnetic resonance spectroscopy. ( Bandou, K; Harada, M; Kannuki, S; Miyoshi, H; Nishitani, H; Tanouchi, M, 1995)
" The spectra from meningiomas, neuroblastomas, and glioblastomas displayed, in addition to similarities-including the presence of signals from leucine, isoleucine, valine, threonine, lactate, acetate, glutamate, choline-containing compounds and glycine-certain distinguishing metabolic features."3.69Characteristic metabolic profiles revealed by 1H NMR spectroscopy for three types of human brain and nervous system tumours. ( Bhakoo, KK; Florian, CL; Noble, M; Preece, NE; Williams, SR, 1995)
"We examined 120 patients with brain tumors using a 1."1.31In vivo proton magnetic resonance spectroscopy of brain tumors. ( Fountas, KN; Gotsis, SD; Johnston, KW; Kapsalaki, EZ; Kapsalakis, JZ; Papadakis, N; Robinson, JS; Smisson , HF, 2000)
"Seventeen brain tumors were measured by 1H-CSI (chemical shift imaging) in a 1."1.30Evaluation of metabolic heterogeneity in brain tumors using 1H-chemical shift imaging method. ( Furuya, S; Ide, M; Kizu, O; Maeda, T; Morishita, H; Naruse, S; Ueda, S, 1997)
"Necrosis was present histologically in four of the five meningiomas classified either as atypical or papillary."1.30Noninvasive evaluation of the malignant potential of intracranial meningiomas performed using proton magnetic resonance spectroscopy. ( Handa, J; Inubushi, T; Matsuda, M; Morikawa, S; Nakasu, S; Shino, A, 1999)
"Choline was elevated in the cellular portion of both tumors but decreased in the necrotic or cystic portions."1.29Localized in vivo 1H magnetic resonance spectroscopy and in vitro analyses of heterogeneous brain tumors. ( Booth, RA; Buchthal, SD; Chang, L; Cornford, M; Ernst, TM; Jenden, D; McBride, D; Miller, BL, 1995)
"Meningiomas were further characterized by the presence of alanine."1.29Determination of proton metabolite concentrations and relaxation parameters in normal human brain and intracranial tumours. ( Blackband, SJ; Horsman, A; Lowry, M; Manton, DJ, 1995)
"Higher grades of brain tumors in this study were associated with higher Cho/reference and lower NAA/reference values."1.29Noninvasive evaluation of malignancy of brain tumors with proton MR spectroscopy. ( Arai, N; Fujiwara, S; Hara, K; Kayama, T; Kumabe, T; Ono, Y; Sato, K; Shimizu, H; Tominaga, T; Yoshimoto, T, 1996)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.33)18.7374
1990's14 (46.67)18.2507
2000's10 (33.33)29.6817
2010's4 (13.33)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
De Stefano, FA1
Morell, AA1
Smith, G1
Warner, T1
Soldozy, S1
Elarjani, T1
Eichberg, DG1
Luther, E1
Komotar, RJ1
Lin, MC1
Li, CZ1
Hsieh, CC1
Hong, KT1
Lin, BJ1
Lin, C1
Tsai, WC1
Lee, CH1
Lee, MG1
Chung, TT1
Tang, CT1
Ju, DT1
Ma, HI1
Liu, MY1
Chen, YH1
Hueng, DY1
Stadler, KL1
Ober, CP1
Feeney, DA1
Jessen, CR1
Yue, Q1
Isobe, T1
Shibata, Y1
Anno, I1
Kawamura, H1
Yamamoto, Y1
Takano, S1
Matsumura, A1
Pfisterer, WK1
Nieman, RA1
Scheck, AC1
Coons, SW1
Spetzler, RF1
Preul, MC2
Righi, V1
Tugnoli, V1
Mucci, A1
Bacci, A1
Bonora, S1
Schenetti, L1
Howe, FA1
Barton, SJ1
Cudlip, SA1
Stubbs, M1
Saunders, DE1
Murphy, M1
Wilkins, P1
Opstad, KS1
Doyle, VL1
McLean, MA1
Bell, BA1
Griffiths, JR1
Bulakbasi, N1
Kocaoglu, M1
Ors, F1
Tayfun, C1
Uçöz, T1
Galanaud, D1
Nicoli, F1
Le Fur, Y1
Roche, P1
Confort-Gouny, S1
Dufour, H1
Ranjeva, JP1
Peragut, JC1
Viout, P1
Cozzone, PJ1
Bendszus, M2
Martin-Schrader, I1
Schlake, HP1
Solymosi, L2
Dydak, U1
Meier, D1
Lamerichs, R1
Boesiger, P1
Hazany, S1
Hesselink, JR1
Healy, JF1
Imbesi, SG1
Poptani, H1
Gupta, RK1
Roy, R1
Pandey, R1
Jain, VK1
Chhabra, DK1
Chang, L1
McBride, D1
Miller, BL1
Cornford, M1
Booth, RA1
Buchthal, SD1
Ernst, TM1
Jenden, D1
Harada, M1
Tanouchi, M1
Nishitani, H1
Miyoshi, H1
Bandou, K1
Kannuki, S1
Kamada, K1
Houkin, K1
Hida, K1
Matsuzawa, H1
Iwasaki, Y1
Abe, H1
Nakada, T1
Manton, DJ1
Lowry, M1
Blackband, SJ1
Horsman, A1
Caramanos, Z1
Collins, DL1
Villemure, JG1
Leblanc, R1
Olivier, A1
Pokrupa, R1
Arnold, DL1
Shimizu, H1
Kumabe, T1
Tominaga, T1
Kayama, T1
Hara, K1
Ono, Y1
Sato, K1
Arai, N1
Fujiwara, S1
Yoshimoto, T1
Florian, CL1
Preece, NE1
Bhakoo, KK1
Williams, SR1
Noble, M1
Kinoshita, Y1
Yokota, A1
Furuya, S1
Naruse, S1
Ide, M1
Morishita, H1
Kizu, O1
Ueda, S1
Maeda, T1
Luan, W1
Zhang, J1
Shino, A1
Nakasu, S1
Matsuda, M1
Handa, J1
Morikawa, S1
Inubushi, T1
Fountas, KN1
Kapsalaki, EZ1
Gotsis, SD1
Kapsalakis, JZ1
Smisson , HF1
Johnston, KW1
Robinson, JS1
Papadakis, N1
Warmuth-Metz, M1
Burger, R1
Klein, R1
Tonn, JC1
Czernicki, Z1
Horsztyński, D1
Jankowski, W1
Grieb, P1
Walecki, J1
Peeling, J1
Sutherland, G1
Henriksen, O1
Wieslander, S1
Gjerris, F1
Jensen, KM1
Kirsch, WM1
Schulz, Q1
Van Buskirk, J1
Nakane, P1

Reviews

2 reviews available for creatine and Meningioma

ArticleYear
Unique magnetic resonance spectroscopy profile of intracranial meningiomas compared to gliomas: a systematic review.
    Acta neurologica Belgica, 2023, Volume: 123, Issue:6

    Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Female; Glioma; Humans; Magnetic Resonance Spectr

2023
Anaerobic energy metabolism in brain tumors.
    Progress in experimental tumor research, 1972, Volume: 17

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aerobiosis; Anaerobiosis; An

1972

Trials

1 trial available for creatine and Meningioma

ArticleYear
Utilization of glutamate/creatine ratios for proton spectroscopic diagnosis of meningiomas.
    Neuroradiology, 2007, Volume: 49, Issue:2

    Topics: Adult; Aged; Alanine; Biomarkers; Brain; Creatine; Female; Glutamic Acid; Glutathione; Humans; Magne

2007

Other Studies

27 other studies available for creatine and Meningioma

ArticleYear
Preoperative grading of intracranial meningioma by magnetic resonance spectroscopy (1H-MRS).
    PloS one, 2018, Volume: 13, Issue:11

    Topics: Adult; Aged; Aspartic Acid; Choline; Creatine; Female; Humans; Male; Meningeal Neoplasms; Meningioma

2018
Multivoxel proton magnetic resonance spectroscopy of inflammatory and neoplastic lesions of the canine brain at 3.0 T.
    American journal of veterinary research, 2014, Volume: 75, Issue:11

    Topics: Analysis of Variance; Animals; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Diagnosis,

2014
New observations concerning the interpretation of magnetic resonance spectroscopy of meningioma.
    European radiology, 2008, Volume: 18, Issue:12

    Topics: Adult; Aged; Biomarkers, Tumor; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy;

2008
Using ex vivo proton magnetic resonance spectroscopy to reveal associations between biochemical and biological features of meningiomas.
    Neurosurgical focus, 2010, Volume: 28, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Alanine; Biomarkers, Tumor; Choline; Creatine; Diagnosis, Differenti

2010
MRS study of meningeal hemangiopericytoma and edema: a comparison with meningothelial meningioma.
    Oncology reports, 2012, Volume: 28, Issue:4

    Topics: 3-Hydroxybutyric Acid; Alanine; Aspartic Acid; Brain Edema; Choline; Creatine; Glutamic Acid; Glutat

2012
Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy.
    Magnetic resonance in medicine, 2003, Volume: 49, Issue:2

    Topics: Alanine; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Glioblastoma; Humans; Inosi

2003
Combination of single-voxel proton MR spectroscopy and apparent diffusion coefficient calculation in the evaluation of common brain tumors.
    AJNR. American journal of neuroradiology, 2003, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Aged; Alanine; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creat

2003
[Contribution of magnetic resonance spectrometry to the diagnosis of intracranial tumors].
    Annales de medecine interne, 2002, Volume: 153, Issue:8

    Topics: Aspartic Acid; Biomarkers; Brain Abscess; Brain Neoplasms; Choline; Computer Graphics; Creatine; Dia

2002
Embolisation of intracranial meningiomas without subsequent surgery.
    Neuroradiology, 2003, Volume: 45, Issue:7

    Topics: Adolescent; Adult; Aged; Alanine; Angiography; Child; Choline; Creatine; Embolization, Therapeutic;

2003
Trading spectral separation at 3T for acquisition speed in multi spin-echo spectroscopic imaging.
    AJNR. American journal of neuroradiology, 2006, Volume: 27, Issue:7

    Topics: Aspartic Acid; Brain; Choline; Creatine; Humans; Image Enhancement; Image Processing, Computer-Assis

2006
Characterization of intracranial mass lesions with in vivo proton MR spectroscopy.
    AJNR. American journal of neuroradiology, 1995, Volume: 16, Issue:8

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Child; Choline; Crea

1995
Localized in vivo 1H magnetic resonance spectroscopy and in vitro analyses of heterogeneous brain tumors.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 1995, Volume: 5, Issue:3

    Topics: Adult; Brain Neoplasms; Choline; Creatine; Female; Glycerylphosphorylcholine; Humans; Hydrogen; Lact

1995
Non-invasive characterization of brain tumor by in-vivo proton magnetic resonance spectroscopy.
    Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:3

    Topics: Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Ependymoma; Glioma; Humans; Magnetic

1995
Localized proton spectroscopy of focal brain pathology in humans: significant effects of edema on spin-spin relaxation time.
    Magnetic resonance in medicine, 1994, Volume: 31, Issue:5

    Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Brain; Brain Edema; Brain Ischemia; Brain Neoplasms; Cerebr

1994
Determination of proton metabolite concentrations and relaxation parameters in normal human brain and intracranial tumours.
    NMR in biomedicine, 1995, Volume: 8, Issue:3

    Topics: Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Cerebellum; Creatine; Humans; Magnetic Resonance

1995
Accurate, noninvasive diagnosis of human brain tumors by using proton magnetic resonance spectroscopy.
    Nature medicine, 1996, Volume: 2, Issue:3

    Topics: Adult; Alanine; Aspartic Acid; Astrocytoma; Biomarkers; Brain; Brain Neoplasms; Choline; Creatine; D

1996
Noninvasive evaluation of malignancy of brain tumors with proton MR spectroscopy.
    AJNR. American journal of neuroradiology, 1996, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Energy Metabolism; Femal

1996
Characteristic metabolic profiles revealed by 1H NMR spectroscopy for three types of human brain and nervous system tumours.
    NMR in biomedicine, 1995, Volume: 8, Issue:6

    Topics: Alanine; Amino Acids; Brain Neoplasms; Choline; Chromatography, High Pressure Liquid; Creatine; Glio

1995
Absolute concentrations of metabolites in human brain tumors using in vitro proton magnetic resonance spectroscopy.
    NMR in biomedicine, 1997, Volume: 10, Issue:1

    Topics: Adenoma; Adolescent; Adult; Aged; Amino Acids; Brain; Brain Neoplasms; Child; Choline; Creatine; Fem

1997
Evaluation of metabolic heterogeneity in brain tumors using 1H-chemical shift imaging method.
    NMR in biomedicine, 1997, Volume: 10, Issue:1

    Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Evaluation Studies as Topic; Glioma; Humans; Imag

1997
In vivo hydrogen-1 magnetic resonance spectroscopy study of human intracranial tumors.
    Chinese medical journal, 1998, Volume: 111, Issue:1

    Topics: Adolescent; Adult; Aged; Astrocytoma; Brain; Brain Neoplasms; Choline; Creatine; Female; Humans; Mag

1998
Noninvasive evaluation of the malignant potential of intracranial meningiomas performed using proton magnetic resonance spectroscopy.
    Journal of neurosurgery, 1999, Volume: 91, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antigens, Nuclear; Biomarkers, Tumor; Brain; Cell Division; Cell Tra

1999
In vivo proton magnetic resonance spectroscopy of brain tumors.
    Stereotactic and functional neurosurgery, 2000, Volume: 74, Issue:2

    Topics: Adult; Aged; Amino Acids; Aspartic Acid; Astrocytoma; Brain; Brain Abscess; Brain Neoplasms; Choline

2000
Diagnosing dural metastases: the value of 1H magnetic resonance spectroscopy.
    Neuroradiology, 2001, Volume: 43, Issue:4

    Topics: Aged; Angiography; Aspartic Acid; Choline; Contrast Media; Creatine; Dura Mater; Female; Humans; Lac

2001
Malignancy of brain tumors evaluated by proton magnetic resonance spectroscopy (1H-MRS) in vitro.
    Acta neurochirurgica. Supplement, 2000, Volume: 76

    Topics: Biopsy; Brain; Brain Neoplasms; Creatine; Diagnosis, Differential; Energy Metabolism; Glioma; Humans

2000
High-resolution 1H NMR spectroscopy studies of extracts of human cerebral neoplasms.
    Magnetic resonance in medicine, 1992, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Amino Acids; Astrocytoma; Brain; Brain Neoplasm

1992
In vivo 1H-spectroscopy of human intracranial tumors at 1.5 tesla. Preliminary experience at a clinical installation.
    Acta radiologica (Stockholm, Sweden : 1987), 1991, Volume: 32, Issue:2

    Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Female; Humans; Lactate

1991