creatine has been researched along with MS (Multiple Sclerosis) in 87 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effectiveness of ingesting creatine monohydrate in elevating intramuscular creatine stores and improving exercise capacity in individuals with multiple sclerosis (MS)." | 9.10 | Influence of creatine monohydrate ingestion on muscle metabolites and intense exercise capacity in individuals with multiple sclerosis. ( Archer, RL; Carrithers, JA; Evans, WJ; Fink, WJ; Lambert, CP; Trappe, TA, 2003) |
| "Creatine did not enhance muscle power in knee extension (p = 0." | 6.73 | Effect of creatine supplementation on muscle capacity in individuals with multiple sclerosis. ( Cotugna, N; Fang, CS; Malin, SK, 2008) |
| "Acute secondary progressive multiple sclerosis (SPMS) is characterized by escalating neurological disability, with limited disease-modifying therapeutic options." | 5.72 | Guanidinoacetate-creatine in secondary progressive multiple sclerosis: a case report. ( Jezdimirovic, T; Ostojic, J; Ostojic, SM; Stajer, V; Zanini, D, 2022) |
| " Neuroimaging measures were central (ventricular) cerebral atrophy, lesion volume, and ratios of N-acetyl aspartate (NAA) to both creatine and choline." | 5.10 | Cognitive performance and MR markers of cerebral injury in cognitively impaired MS patients. ( Christodoulou, C; Huang, W; Krupp, LB; Li, L; Li, X; Liang, Z; MacAllister, WS; Melville, P; Morgan, T; Peyster, R; Roche, P; Roque, C; Scherl, WF; Tudorica, LA, 2003) |
| "To evaluate the effectiveness of ingesting creatine monohydrate in elevating intramuscular creatine stores and improving exercise capacity in individuals with multiple sclerosis (MS)." | 5.10 | Influence of creatine monohydrate ingestion on muscle metabolites and intense exercise capacity in individuals with multiple sclerosis. ( Archer, RL; Carrithers, JA; Evans, WJ; Fink, WJ; Lambert, CP; Trappe, TA, 2003) |
| "Meta-analysis was performed on the results of 75 comparisons from the 30 peer-reviewed publications that used proton magnetic resonance spectroscopy (1H-MRS) or spectroscopic imaging to (i) quantify the mean concentrations of total creatine (tCr, found in neurons, astrocytes and oligodendrocytes), and/or total N-acetyl groups (tNA, found only in neurons), in the lesional and/or non-lesional white matter (WM) and/or the grey matter (GM) of patients with multiple sclerosis (MS) and (ii) compare these values with those in the homologous tissues of normal controls (NC)." | 4.82 | 1H-MRS quantification of tNA and tCr in patients with multiple sclerosis: a meta-analytic review. ( Arnold, DL; Caramanos, Z; Narayanan, S, 2005) |
| "Since there were no changes in NAA concentration, the increase in tCr may be suggestive of gliosis, or an imbalanced equilibrium of the creatine and phosphocreatine ratio in the pons of relapsing-remitting MS patients with fatigue." | 3.83 | Fatigue in Multiple Sclerosis: Assessing Pontine Involvement Using Proton MR Spectroscopic Imaging. ( Beaulieu, C; Giuliani, F; Hanstock, C; Kalra, S; Zaini, WH, 2016) |
| "To evaluate the prognostic value of the cortical N-acetyl aspartate to creatine ratio (NAA/Cr) in early relapsing-remitting multiple sclerosis (RRMS)." | 3.80 | Cortical N-acetyl aspartate is a predictor of long-term clinical disability in multiple sclerosis. ( Blinkenberg, M; Hanson, LG; Mathiesen, HK; Paulson, OB; Skimminge, A; Sorensen, PS; Wu, X, 2014) |
| "The N-acetylaspartate-creatine ratio (NAA/Cr) was significantly lower in the high-fatigue group than the low-fatigue group (mean +/- SD, 2." | 3.72 | The relationship between diffuse axonal damage and fatigue in multiple sclerosis. ( Arnold, DL; De Stefano, N; Francis, SJ; Lapierre, Y; Narayanan, S; Santos, AC; Tartaglia, MC, 2004) |
| "The current study was designed to determine the relative distribution of decreases of N-acetylasparate (NAA), a marker of axonal damage, between lesions and normal-appearing white matter of patients with established multiple sclerosis and to test for associations between changes in the ratio of NAA to creatine/phosphocreatine (NAA:Cr) in those compartments and changes in disability." | 3.70 | Imaging axonal damage of normal-appearing white matter in multiple sclerosis. ( Antel, JP; Arnold, DL; De Stefano, N; Francis, GS; Fu, L; Matthews, PM; Narayanan, S; Wolfson, C; Worsley, KJ, 1998) |
| "The aim of this research was to obtain an absolute quantification of the N-acetyl-aspartate, choline, creatine and phosphocreatine levels in normal-appearing white matter by means of 1H magnetic resonance spectroscopy in a group of multiple sclerosis patients (27 with the relapsing-remitting form and 13 with the secondary progressive form)." | 3.70 | Absolute quantification of brain metabolites by proton magnetic resonance spectroscopy in normal-appearing white matter of multiple sclerosis patients. ( Alberti, A; Chiarini, P; Gallai, V; Gobbi, G; Pelliccioli, GP; Presciutti, O; Sarchielli, P; Tarducci, R; Vicinanza, F, 1999) |
| "Localized short echo time (TE = 20 ms), stimulated echo acquisition mode, and double spin echo (TE = 135 ms) proton spectroscopy were performed in clearly defined, acute Gadolinium (Gd)-enhancing multiple sclerosis (MS) plaques of 22 patients with clinically definite MS." | 3.69 | Proton MRS of gadolinium-enhancing MS plaques and metabolic changes in normal-appearing white matter. ( Brunnschweiler, H; Hagberg, G; Kappos, L; Mader, I; Radue, EW; Roser, W; Seelig, J, 1995) |
| " We report a longitudinal study in which changes in the N-acetylaspartate to creatine resonance intensity ratio measured by brain proton magnetic resonance spectroscopy were used to follow the progression of brain pathology in 7 patients with multiple sclerosis over an 18-month period." | 3.69 | Use of proton magnetic resonance spectroscopy for monitoring disease progression in multiple sclerosis. ( Antel, JP; Arnold, DL; Collins, DL; Francis, GS; Matthews, PM; Riess, GT; Wolfson, C, 1994) |
| "The goals of the current study were threefold: first, to confirm previous single volume proton (1H) magnetic resonance spectroscopy results of reduced N-acetyl aspartate (NAA, a putative marker of neurons) in multiple sclerosis (MS) white matter lesions using multiple volume 1H magnetic resonance spectroscopic imaging (MRSI); second, to measure the phospholipid metabolites phosphomonoesters and phosphodiesters in such lesions using phosphorus (31P) MRSI; and third, to test the hypothesis that biochemical changes occur in the normal-appearing (on spin echo T2-weighted magnetic resonance images) white matter in patients with MS." | 3.69 | Biochemical alterations in multiple sclerosis lesions and normal-appearing white matter detected by in vivo 31P and 1H spectroscopic imaging. ( de Bie, SH; Fein, G; Goodin, DS; Hugg, JW; Husted, CA; Matson, GB; Maudsley, AA; Tsuruda, JS; Weiner, MW, 1994) |
| "Creatine did not enhance muscle power in knee extension (p = 0." | 2.73 | Effect of creatine supplementation on muscle capacity in individuals with multiple sclerosis. ( Cotugna, N; Fang, CS; Malin, SK, 2008) |
| "Acute secondary progressive multiple sclerosis (SPMS) is characterized by escalating neurological disability, with limited disease-modifying therapeutic options." | 1.72 | Guanidinoacetate-creatine in secondary progressive multiple sclerosis: a case report. ( Jezdimirovic, T; Ostojic, J; Ostojic, SM; Stajer, V; Zanini, D, 2022) |
| "Most of the brain tumors were characterized by strongly reduced total N-acetylaspartyl compounds and marked increases of myo-inositol and choline-containing compounds, consistent with a lack of neuroaxonal tissue and a proliferation of glial cells." | 1.31 | Quantitative proton magnetic resonance spectroscopy of focal brain lesions. ( Dechent, P; Frahm, J; Hanefeld, F; Herms, J; Markakis, E; Maxton, C; Wilken, B, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (3.45) | 18.7374 |
| 1990's | 29 (33.33) | 18.2507 |
| 2000's | 36 (41.38) | 29.6817 |
| 2010's | 15 (17.24) | 24.3611 |
| 2020's | 4 (4.60) | 2.80 |
| Authors | Studies |
|---|---|
| Ostojic, SM | 2 |
| Ostojic, J | 1 |
| Zanini, D | 1 |
| Jezdimirovic, T | 1 |
| Stajer, V | 1 |
| Mueller, C | 1 |
| Baird, JF | 1 |
| Motl, RW | 1 |
| Hnilicová, P | 1 |
| Kantorová, E | 1 |
| Poláček, H | 1 |
| Grendár, M | 1 |
| Bittšanský, M | 1 |
| Čierny, D | 1 |
| Sivák, Š | 1 |
| Zeleňák, K | 1 |
| Lehotský, J | 1 |
| Dobrota, D | 1 |
| Kurča, E | 1 |
| Meknatkhah, S | 1 |
| Dashti, PS | 1 |
| Raminfard, S | 1 |
| Rad, HS | 2 |
| Mousavi, MS | 1 |
| Riazi, GH | 1 |
| Bodini, B | 1 |
| Branzoli, F | 1 |
| Poirion, E | 1 |
| García-Lorenzo, D | 1 |
| Didier, M | 1 |
| Maillart, E | 1 |
| Socha, J | 1 |
| Bera, G | 1 |
| Lubetzki, C | 1 |
| Ronen, I | 1 |
| Lehericy, S | 1 |
| Stankoff, B | 1 |
| Evans, E | 1 |
| Piccio, L | 1 |
| Cross, AH | 1 |
| D'haeseleer, M | 1 |
| Steen, C | 1 |
| Hoogduin, JM | 1 |
| van Osch, MJ | 1 |
| Fierens, Y | 1 |
| Cambron, M | 1 |
| Koch, MW | 1 |
| De Keyser, J | 3 |
| Tisell, A | 2 |
| Leinhard, OD | 1 |
| Warntjes, JB | 1 |
| Aalto, A | 1 |
| Smedby, Ö | 1 |
| Landtblom, AM | 3 |
| Lundberg, P | 2 |
| Stromillo, ML | 2 |
| Giorgio, A | 1 |
| Rossi, F | 1 |
| Battaglini, M | 1 |
| Hakiki, B | 1 |
| Malentacchi, G | 1 |
| Santangelo, M | 1 |
| Gasperini, C | 1 |
| Bartolozzi, ML | 3 |
| Portaccio, E | 1 |
| Amato, MP | 1 |
| De Stefano, N | 14 |
| Bellenberg, B | 1 |
| Busch, M | 1 |
| Trampe, N | 1 |
| Gold, R | 1 |
| Chan, A | 1 |
| Lukas, C | 1 |
| Szafirska, M | 1 |
| Urbanik, A | 1 |
| Róg, T | 1 |
| Wu, X | 1 |
| Hanson, LG | 1 |
| Skimminge, A | 1 |
| Sorensen, PS | 1 |
| Paulson, OB | 1 |
| Mathiesen, HK | 1 |
| Blinkenberg, M | 1 |
| Vafaeyan, H | 1 |
| Ebrahimzadeh, SA | 1 |
| Rahimian, N | 1 |
| Alavijeh, SK | 1 |
| Madadi, A | 1 |
| Faeghi, F | 1 |
| Harirchian, MH | 1 |
| Zaini, WH | 1 |
| Giuliani, F | 1 |
| Beaulieu, C | 1 |
| Kalra, S | 1 |
| Hanstock, C | 1 |
| Duan, Y | 1 |
| Liu, Z | 1 |
| Liu, Y | 1 |
| Huang, J | 1 |
| Ren, Z | 1 |
| Sun, Z | 1 |
| Chen, H | 1 |
| Dong, H | 1 |
| Ye, J | 1 |
| Li, K | 1 |
| Toprak, MK | 1 |
| Cakir, B | 1 |
| Ulu, EM | 1 |
| Arat, Z | 1 |
| Benli, US | 1 |
| Can, U | 1 |
| Ağildere, M | 1 |
| Kirov, II | 1 |
| Patil, V | 1 |
| Babb, JS | 2 |
| Rusinek, H | 2 |
| Herbert, J | 1 |
| Gonen, O | 2 |
| Aboul-Enein, F | 1 |
| Krssák, M | 1 |
| Höftberger, R | 1 |
| Prayer, D | 1 |
| Kristoferitsch, W | 1 |
| Malin, SK | 1 |
| Cotugna, N | 1 |
| Fang, CS | 1 |
| Davydovskaia, MV | 1 |
| Boĭko, AN | 1 |
| Podoprigora, AE | 1 |
| Pronin, IN | 1 |
| Kornienko, VN | 1 |
| Gusev, EI | 1 |
| Mellergård, J | 1 |
| Dahlqvist Leinhard, O | 1 |
| Blystad, I | 1 |
| Blennow, K | 1 |
| Olsson, B | 1 |
| Dahle, C | 1 |
| Ernerudh, J | 1 |
| Vrethem, M | 1 |
| Kapeller, P | 2 |
| Brex, PA | 2 |
| Chard, D | 1 |
| Dalton, C | 1 |
| Griffin, CM | 1 |
| McLean, MA | 3 |
| Parker, GJ | 2 |
| Thompson, AJ | 4 |
| Miller, DH | 5 |
| Sarchielli, P | 2 |
| Presciutti, O | 2 |
| Tarducci, R | 2 |
| Gobbi, G | 2 |
| Alberti, A | 2 |
| Pelliccioli, GP | 2 |
| Chiarini, P | 2 |
| Gallai, V | 2 |
| Parry, A | 1 |
| Corkill, R | 1 |
| Blamire, AM | 1 |
| Palace, J | 1 |
| Narayanan, S | 12 |
| Arnold, D | 1 |
| Styles, P | 1 |
| Matthews, PM | 11 |
| Christodoulou, C | 1 |
| Krupp, LB | 1 |
| Liang, Z | 1 |
| Huang, W | 1 |
| Melville, P | 1 |
| Roque, C | 1 |
| Scherl, WF | 1 |
| Morgan, T | 1 |
| MacAllister, WS | 1 |
| Li, L | 1 |
| Tudorica, LA | 1 |
| Li, X | 1 |
| Roche, P | 1 |
| Peyster, R | 1 |
| Inglese, M | 1 |
| Li, BS | 1 |
| Grossman, RI | 3 |
| Lambert, CP | 1 |
| Archer, RL | 1 |
| Carrithers, JA | 1 |
| Fink, WJ | 1 |
| Evans, WJ | 1 |
| Trappe, TA | 1 |
| Watanabe, H | 1 |
| Fukatsu, H | 1 |
| Ito, T | 1 |
| Iijima, M | 1 |
| Mabuchi, N | 1 |
| Sobue, G | 1 |
| BRADLOW, HL | 1 |
| FUKUSHIMA, DK | 1 |
| GALLAGHER, TF | 1 |
| HELLMAN, L | 1 |
| HOFMANN, K | 1 |
| LI, CH | 1 |
| ROSENFELD, RS | 1 |
| SPENCER, H | 1 |
| ZUMOFF, B | 1 |
| Tartaglia, MC | 2 |
| Francis, SJ | 1 |
| Santos, AC | 1 |
| Lapierre, Y | 1 |
| Arnold, DL | 14 |
| Pirko, I | 1 |
| Johnson, A | 1 |
| Gamez, J | 1 |
| Macura, SI | 1 |
| Rodriguez, M | 1 |
| Hu, J | 1 |
| Xu, Y | 1 |
| Jiang, Q | 1 |
| Sehgal, V | 1 |
| Shen, Y | 2 |
| Xuan, Y | 1 |
| Xia, Y | 1 |
| Fernando, KT | 1 |
| Chard, DT | 1 |
| MacManus, DG | 2 |
| Dalton, CM | 1 |
| Miszkiel, KA | 1 |
| Gordon, RM | 1 |
| Plant, GT | 1 |
| Kendi, AT | 1 |
| Tan, FU | 1 |
| Kendi, M | 1 |
| Yilmaz, S | 1 |
| Huvaj, S | 1 |
| Tellioğlu, S | 1 |
| Siger-Zajdel, M | 2 |
| Selmaj, KW | 1 |
| Ropele, S | 1 |
| Enzinger, C | 1 |
| Lahousen, T | 1 |
| Strasser-Fuchs, S | 1 |
| Schmidt, R | 1 |
| Fazekas, F | 1 |
| Guidi, L | 2 |
| Federico, A | 2 |
| Sijens, PE | 2 |
| Mostert, JP | 2 |
| Oudkerk, M | 2 |
| Caramanos, Z | 1 |
| Selmaj, K | 1 |
| Cianfoni, A | 1 |
| Niku, S | 1 |
| Imbesi, SG | 1 |
| Filippi, M | 3 |
| Wattjes, MP | 2 |
| Harzheim, M | 2 |
| Lutterbey, GG | 2 |
| Klotz, L | 1 |
| Schild, HH | 2 |
| Träber, F | 2 |
| Bogdanow, M | 1 |
| Khan, O | 1 |
| Bao, F | 1 |
| Caon, C | 1 |
| Tselis, A | 1 |
| Latif, Z | 1 |
| Zak, I | 1 |
| Roser, W | 1 |
| Hagberg, G | 1 |
| Mader, I | 1 |
| Brunnschweiler, H | 1 |
| Radue, EW | 1 |
| Seelig, J | 1 |
| Kappos, L | 1 |
| Davies, SE | 1 |
| Newcombe, J | 1 |
| Williams, SR | 1 |
| McDonald, WI | 2 |
| Clark, JB | 1 |
| Hiehle, JF | 1 |
| Lenkinski, RE | 2 |
| Dousset, V | 1 |
| Ramer, KN | 1 |
| Schnall, MD | 1 |
| Cohen, JA | 1 |
| Gonzalez-Scarano, F | 2 |
| Riess, GT | 1 |
| Francis, GS | 9 |
| Collins, DL | 3 |
| Wolfson, C | 3 |
| Antel, JP | 9 |
| Husted, CA | 1 |
| Goodin, DS | 1 |
| Hugg, JW | 1 |
| Maudsley, AA | 2 |
| Tsuruda, JS | 1 |
| de Bie, SH | 1 |
| Fein, G | 1 |
| Matson, GB | 1 |
| Weiner, MW | 2 |
| Wu, Z | 1 |
| Meyerhoff, DJ | 1 |
| Davie, CA | 2 |
| Hawkins, CP | 1 |
| Barker, GJ | 3 |
| Brennan, A | 1 |
| Tofts, PS | 1 |
| Hetherington, HP | 3 |
| Pan, JW | 3 |
| Mason, GF | 1 |
| Adams, D | 1 |
| Vaughn, MJ | 1 |
| Twieg, DB | 2 |
| Pohost, GM | 2 |
| Vaughan, JT | 1 |
| Mitchell, G | 1 |
| Whitaker, JN | 1 |
| Sjöqvist, L | 1 |
| Söderfeldt, B | 1 |
| Nyland, H | 1 |
| Thuomas, KA | 1 |
| Kimura, H | 1 |
| Tourbah, A | 1 |
| Stievenart, JL | 1 |
| Iba-Zizen, MT | 1 |
| Zannoli, G | 1 |
| Lyon-Caen, O | 1 |
| Cabanis, EA | 1 |
| Fu, L | 4 |
| Pioro, E | 1 |
| Worsley, KJ | 2 |
| Peters, AR | 1 |
| Geelen, JA | 1 |
| den Boer, JA | 1 |
| Prevo, RL | 1 |
| Minderhoud, JM | 1 |
| 's Gravenmade, EJ | 1 |
| Falini, A | 1 |
| Calabrese, G | 1 |
| Origgi, D | 1 |
| Lipari, S | 1 |
| Colombo, B | 1 |
| Comi, G | 2 |
| Scotti, G | 1 |
| Stanley, J | 1 |
| Kraft, GH | 1 |
| Richards, TL | 1 |
| Heide, AC | 1 |
| Foong, J | 1 |
| Rozewicz, L | 1 |
| Ron, MA | 1 |
| Vicinanza, F | 1 |
| Pike, GB | 1 |
| Helms, G | 1 |
| Stawiarz, L | 1 |
| Kivisäkk, P | 1 |
| Link, H | 1 |
| Leary, SM | 1 |
| Cucurella, MG | 1 |
| Rovira, A | 1 |
| Río, J | 1 |
| Pedraza, S | 1 |
| Tintoré, MM | 1 |
| Montalbán, X | 1 |
| Alonso, J | 1 |
| Wilken, B | 1 |
| Dechent, P | 1 |
| Herms, J | 1 |
| Maxton, C | 1 |
| Markakis, E | 1 |
| Hanefeld, F | 1 |
| Frahm, J | 1 |
| Woermann, FG | 1 |
| Duncan, JS | 1 |
| Simone, IL | 1 |
| Tortorella, C | 1 |
| Federico, F | 1 |
| Liguori, M | 1 |
| Lucivero, V | 1 |
| Giannini, P | 1 |
| Carrara, D | 1 |
| Bellacosa, A | 1 |
| Livrea, P | 1 |
| Arnaoutelis, R | 1 |
| Mainero, C | 1 |
| Iannucci, G | 1 |
| Sormani, MP | 1 |
| Reichel, H | 1 |
| Grüssinger, A | 1 |
| Knehans, A | 1 |
| Kühn, K | 1 |
| Schmidt-Gayk, H | 1 |
| Ritz, E | 1 |
| O'Connor, J | 1 |
| Francis, G | 1 |
| Antel, J | 1 |
| Van Hecke, P | 1 |
| Marchal, G | 1 |
| Johannik, K | 1 |
| Demaerel, P | 1 |
| Wilms, G | 1 |
| Carton, H | 1 |
| Baert, AL | 1 |
| Berlet, HH | 1 |
| Pilz, H | 1 |
| Rinne, UK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Adjuvant Effects of Vitamin A and Vitamin D Supplementation on Treatment of Children With ADHD:A Randomized, Double Blind, Placebo-controlled, Multicentric Trial.[NCT04284059] | Phase 4 | 504 participants (Anticipated) | Interventional | 2021-02-25 | Recruiting | ||
| Regeneration in Cervical Degenerative Myelopathy - a Multi-centre, Double-blind, Randomised, Placebo Controlled Trial Assessing the Efficacy of Ibudilast as an Adjuvant Treatment to Decompressive Surgery for Degenerative Cervical Myelopathy[NCT04631471] | Phase 3 | 400 participants (Anticipated) | Interventional | 2021-12-22 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for creatine and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
Creatine and multiple sclerosis.
Topics: Brain; Creatine; Humans; Multiple Sclerosis; Neurodegenerative Diseases | 2022 |
Use of Vitamins and Dietary Supplements by Patients With Multiple Sclerosis: A Review.
Topics: Acetylcarnitine; Animals; Ascorbic Acid; Biotin; Caffeine; Creatine; Curcumin; Dietary Supplements; | 2018 |
[Magnetic resonance spectroscopy and its clinical applications in multiple sclerosis].
Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Humans; Lactic Acid; Magnetic Resonance Spectroscopy | 2003 |
Magnetic resonance spectroscopy as a measure of brain damage in multiple sclerosis.
Topics: Aspartic Acid; Axons; Brain Diseases; Creatine; Disability Evaluation; Humans; Magnetic Resonance Im | 2005 |
1H-MRS quantification of tNA and tCr in patients with multiple sclerosis: a meta-analytic review.
Topics: Aspartic Acid; Brain; Creatine; Humans; Magnetic Resonance Spectroscopy; Multiple Sclerosis | 2005 |
MR spectroscopy in multiple sclerosis.
Topics: Aspartic Acid; Brain Chemistry; Choline; Creatine; Humans; Magnetic Resonance Spectroscopy; Multiple | 2007 |
Correlations of evoked potentials with MR imaging and MR spectroscopy in multiple sclerosis.
Topics: Aspartic Acid; Brain; Choline; Creatine; Evoked Potentials; Evoked Potentials, Somatosensory; Evoked | 1998 |
Proton MR spectroscopy in multiple sclerosis.
Topics: Aspartic Acid; Brain; Choline; Creatine; Disability Evaluation; Disease Progression; Energy Metaboli | 2000 |
14 trials available for creatine and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
1H-magnetic resonance spectroscopy in diffuse and focal cervical cord lesions in multiple sclerosis.
Topics: Adult; Analysis of Variance; Aspartic Acid; Cervical Vertebrae; Creatine; Cross-Sectional Studies; D | 2013 |
The effects of interferon beta-1a on proton MR spectroscopic imaging in patients with multiple sclerosis, a controlled study, preliminary results.
Topics: Adjuvants, Immunologic; Adult; Aspartic Acid; Biomarkers; Brain Mapping; Central Nervous System; Cho | 2008 |
Effect of creatine supplementation on muscle capacity in individuals with multiple sclerosis.
Topics: Adult; Creatine; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Drug Administration S | 2008 |
Association between change in normal appearing white matter metabolites and intrathecal inflammation in natalizumab-treated multiple sclerosis.
Topics: Adult; Antibodies, Monoclonal, Humanized; Choline; Creatine; Female; Humans; Inflammation; Interleuk | 2012 |
Beta-Interferon treatment does not always slow the progression of axonal injury in multiple sclerosis.
Topics: Adult; Aspartic Acid; Axons; Body Water; Brain Chemistry; Cohort Studies; Creatine; Disease Progress | 2003 |
Cognitive performance and MR markers of cerebral injury in cognitively impaired MS patients.
Topics: Adult; Aspartic Acid; Atrophy; Axons; Biomarkers; Cerebral Cortex; Choline; Cognition Disorders; Cre | 2003 |
Diffusely elevated cerebral choline and creatine in relapsing-remitting multiple sclerosis.
Topics: Adult; Aspartic Acid; Brain; Choline; Corpus Callosum; Creatine; Diffusion; Female; Humans; Magnetic | 2003 |
Influence of creatine monohydrate ingestion on muscle metabolites and intense exercise capacity in individuals with multiple sclerosis.
Topics: Adult; Biopsy, Needle; Creatine; Disability Evaluation; Double-Blind Method; Ergometry; Exercise; Ex | 2003 |
Fluoxetine increases cerebral white matter NAA/Cr ratio in patients with multiple sclerosis.
Topics: Administration, Oral; Adult; Antidepressive Agents, Second-Generation; Aspartic Acid; Cerebral Corte | 2006 |
High field MR imaging and 1H-MR spectroscopy in clinically isolated syndromes suggestive of multiple sclerosis: correlation between metabolic alterations and diagnostic MR imaging criteria.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Mapping; Choline; Creatine; Diagnosis, Differential; | 2008 |
Imaging of axonal damage in multiple sclerosis: spatial distribution of magnetic resonance imaging lesions.
Topics: Adult; Aspartic Acid; Axons; Brain; Creatine; Female; Humans; Image Enhancement; Magnetic Resonance | 1997 |
Regression analysis of metabolite concentrations estimated from localized proton MR spectra of active and chronic multiple sclerosis lesions.
Topics: Acute Disease; Adult; Aged; Aspartic Acid; Brain; Chronic Disease; Contrast Media; Creatine; Female; | 2000 |
Quantitative analysis of short echo time (1)H-MRSI of cerebral gray and white matter.
Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Calibration; Cerebrospinal Fluid; Choline; Creatine; D | 2000 |
Long-term therapy with cyclosporin A does not influence serum concentrations of vitamin D metabolites in patients with multiple sclerosis.
Topics: Adult; Azathioprine; Calcifediol; Calcitriol; Creatine; Cyclosporine; Double-Blind Method; Female; H | 1992 |
65 other studies available for creatine and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
Guanidinoacetate-creatine in secondary progressive multiple sclerosis: a case report.
Topics: Creatine; Female; Glycine; Humans; Magnetic Resonance Spectroscopy; Middle Aged; Multiple Sclerosis; | 2022 |
Whole-Brain Metabolic Abnormalities Are Associated With Mobility in Older Adults With Multiple Sclerosis.
Topics: Aged; Aspartic Acid; Brain; Brain Diseases; Choline; Creatine; Humans; Inositol; Magnetic Resonance | 2022 |
Altered hypothalamic metabolism in early multiple sclerosis - MR spectroscopy study.
Topics: Adult; Aspartic Acid; Choline; Creatine; Female; Glutamic Acid; Glutamine; Humans; Hypothalamus; Ino | 2019 |
The Changes in
Topics: Animals; Aspartic Acid; Creatine; Cuprizone; Female; Glycerylphosphorylcholine; Metabolome; Multiple | 2021 |
Dysregulation of energy metabolism in multiple sclerosis measured in vivo with diffusion-weighted spectroscopy.
Topics: Adult; Aspartic Acid; Atrophy; Creatine; Diffusion Magnetic Resonance Imaging; Energy Metabolism; Fe | 2018 |
Performance on Paced Auditory Serial Addition Test and cerebral blood flow in multiple sclerosis.
Topics: Adult; Aspartic Acid; Case-Control Studies; Cerebrovascular Circulation; Creatine; Disability Evalua | 2013 |
Increased concentrations of glutamate and glutamine in normal-appearing white matter of patients with multiple sclerosis and normal MR imaging brain scans.
Topics: Adult; Aged; Aspartic Acid; Brain; Choline; Creatine; Female; Glutamic Acid; Glutamine; Humans; Inos | 2013 |
Brain metabolic changes suggestive of axonal damage in radiologically isolated syndrome.
Topics: Adult; Aspartic Acid; Axons; Brain; Choline; Creatine; Disease Progression; Female; Humans; Magnetic | 2013 |
[The metabolic abnormalities in plaques of multiple sclerosis patients - the assessment in proton MR spectroscopy (1HMRS)].
Topics: Adult; Aspartic Acid; Axons; Brain; Choline; Creatine; Female; Humans; Lactic Acid; Leukoencephalopa | 2013 |
Cortical N-acetyl aspartate is a predictor of long-term clinical disability in multiple sclerosis.
Topics: Adult; Aspartic Acid; Cerebral Cortex; Creatine; Disability Evaluation; Disease Progression; Female; | 2014 |
Quantification of diagnostic biomarkers to detect multiple sclerosis lesions employing (1)H-MRSI at 3T.
Topics: Adult; Aged; Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Choline; Creatine; Female; Glutathio | 2015 |
Fatigue in Multiple Sclerosis: Assessing Pontine Involvement Using Proton MR Spectroscopic Imaging.
Topics: Adult; Aspartic Acid; Creatine; Fatigue; Female; Humans; Middle Aged; Multiple Sclerosis; Pons; Prot | 2016 |
Metabolic changes in normal-appearing white matter in patients with neuromyelitis optica and multiple sclerosis: a comparative magnetic resonance spectroscopy study.
Topics: Adult; Aspartic Acid; Case-Control Studies; Choline; Creatine; Female; Humans; Magnetic Resonance Sp | 2017 |
MR spectroscopy indicates diffuse multiple sclerosis activity during remission.
Topics: Adult; Aspartic Acid; Brain Chemistry; Choline; Creatine; Female; Humans; Inositol; Magnetic Resonan | 2009 |
Reduced NAA-levels in the NAWM of patients with MS is a feature of progression. A study with quantitative magnetic resonance spectroscopy at 3 Tesla.
Topics: Adult; Aspartic Acid; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy; Male; Midd | 2010 |
[The neurodegenerative process in multiple sclerosis and the possible neuroprotective effect of treatment with Β-interferon 1a (avonex)].
Topics: Adolescent; Adult; Aspartic Acid; Brain Chemistry; Creatine; Female; Humans; Interferon beta-1a; Int | 2012 |
Quantitative 1H MRS imaging 14 years after presenting with a clinically isolated syndrome suggestive of multiple sclerosis.
Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Female; Humans; Inositol; Magnetic Resonance Spectro | 2002 |
Localized (1)H magnetic resonance spectroscopy in mainly cortical gray matter of patients with multiple sclerosis.
Topics: Adult; Aspartic Acid; Atrophy; Creatine; Disease Progression; Female; Humans; Magnetic Resonance Spe | 2002 |
ADRENAL STIMULATION BY ADRENOCORTICOTROPIC PEPTIDES.
Topics: Adrenocorticotropic Hormone; Carbon Isotopes; Chromatography; Creatine; Creatinine; Humans; Hydrocor | 1963 |
The relationship between diffuse axonal damage and fatigue in multiple sclerosis.
Topics: Adult; Aspartic Acid; Axons; Brain Chemistry; Creatine; Cross-Sectional Studies; Fatigue; Female; Hu | 2004 |
Disappearing "T1 black holes" in an animal model of multiple sclerosis.
Topics: Animals; Aspartic Acid; Brain; Brain Chemistry; Cardiovirus Infections; Choline; Creatine; Magnetic | 2004 |
Spectral pattern of total creatine and trimethyl ammonium in multiple sclerosis.
Topics: Creatine; Humans; Magnetic Resonance Spectroscopy; Multiple Sclerosis; Muscle, Skeletal; Quaternary | 2004 |
Elevated white matter myo-inositol in clinically isolated syndromes suggestive of multiple sclerosis.
Topics: Adolescent; Adult; Aspartic Acid; Biomarkers; Brain; Creatine; Female; Humans; Inositol; Magnetic Re | 2004 |
MR spectroscopy of cervical spinal cord in patients with multiple sclerosis.
Topics: Adult; Aspartic Acid; Case-Control Studies; Cervical Vertebrae; Choline; Creatine; Female; Humans; I | 2004 |
Proton magnetic resonance spectroscopy of normal appearing white matter in familial and sporadic multiple sclerosis.
Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Female; Humans; Image Processing, Computer-Assisted; | 2005 |
Discrimination of white matter lesions and multiple sclerosis plaques by short echo quantitative 1H-magnetic resonance spectroscopy.
Topics: Adult; Aged; Analysis of Variance; Aspartic Acid; Brain; Case-Control Studies; Creatine; Female; Fou | 2005 |
(1)H MR spectroscopy of the brain in multiple sclerosis subtypes with analysis of the metabolite concentrations in gray and white matter: initial findings.
Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Energy Metabolism; Female; Humans; Image Processing, | 2006 |
Proton magnetic resonance spectroscopy of normal appearing white matter in asymptomatic relatives of multiple sclerosis patients.
Topics: Adult; Aspartic Acid; Choline; Creatine; Female; Humans; Magnetic Resonance Imaging; Magnetic Resona | 2006 |
Metabolite findings in tumefactive demyelinating lesions utilizing short echo time proton magnetic resonance spectroscopy.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Demyelinating Diseases; | 2007 |
Axonal damage but no increased glial cell activity in the normal-appearing white matter of patients with clinically isolated syndromes suggestive of multiple sclerosis using high-field magnetic resonance spectroscopy.
Topics: Adult; Aspartic Acid; Axons; Brain; Choline; Creatine; Female; Glutamic Acid; Glutamine; Humans; Ino | 2007 |
Long-term study of brain 1H-MRS study in multiple sclerosis: effect of glatiramer acetate therapy on axonal metabolic function and feasibility of long-Term H-MRS monitoring in multiple sclerosis.
Topics: Adult; Aspartic Acid; Axons; Brain; Case-Control Studies; Creatine; Feasibility Studies; Female; Gla | 2008 |
Proton MRS of gadolinium-enhancing MS plaques and metabolic changes in normal-appearing white matter.
Topics: Adult; Brain Chemistry; Choline; Contrast Media; Creatine; Gadolinium; Heterocyclic Compounds; Human | 1995 |
High resolution proton NMR spectroscopy of multiple sclerosis lesions.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain; Cadaver; Creatine; Humans; Magnetic Resonance | 1995 |
Correlation of spectroscopy and magnetization transfer imaging in the evaluation of demyelinating lesions and normal appearing white matter in multiple sclerosis.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Choline; Cohort Studies; Creatine; Demyelinating Dise | 1994 |
Use of proton magnetic resonance spectroscopy for monitoring disease progression in multiple sclerosis.
Topics: Aspartic Acid; Axons; Brain; Creatine; Follow-Up Studies; Humans; Longitudinal Studies; Magnetic Res | 1994 |
Biochemical alterations in multiple sclerosis lesions and normal-appearing white matter detected by in vivo 31P and 1H spectroscopic imaging.
Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy; Mal | 1994 |
Automated processing for proton spectroscopic imaging using water reference deconvolution.
Topics: Artifacts; Aspartic Acid; Body Water; Brain; Choline; Creatine; Electronic Data Processing; Fourier | 1994 |
Serial proton magnetic resonance spectroscopy in acute multiple sclerosis lesions.
Topics: Adult; Aspartic Acid; Creatine; Female; Gadolinium DTPA; Humans; Magnetic Resonance Imaging; Magneti | 1994 |
Quantitative 1H spectroscopic imaging of human brain at 4.1 T using image segmentation.
Topics: Aspartic Acid; Basal Ganglia; Brain; Cerebral Cortex; Cerebrospinal Fluid; Choline; Confidence Inter | 1996 |
Evaluation of multiple sclerosis by 1H spectroscopic imaging at 4.1 T.
Topics: Adult; Aspartic Acid; Astrocytes; Axons; Brain; Cell Membrane; Cerebral Ventricles; Choline; Creatin | 1996 |
Proton MR spectroscopy and MR imaging in acute and chronic multiple sclerosis--ringlike appearances in acute plaques.
Topics: Adult; Aged; Aspartic Acid; Brain; Case-Control Studies; Choline; Creatine; Female; Humans; Inositol | 1996 |
Proton MR spectroscopy and magnetization transfer ratio in multiple sclerosis: correlative findings of active versus irreversible plaque disease.
Topics: Adult; Aspartic Acid; Brain; Brain Diseases; Brain Edema; Choline; Chronic Disease; Creatine; Demyel | 1996 |
In vivo localized NMR proton spectroscopy of normal appearing white matter in patients with multiple sclerosis.
Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Brain Diseases; Choline; Clinical Trials as Topic | 1996 |
Statistics for investigation of multimodal MR imaging data and an application to multiple sclerosis patients.
Topics: Aspartic Acid; Brain; Creatine; Disease Progression; Humans; Image Interpretation, Computer-Assisted | 1996 |
Axonal dysfunction and disability in a relapse of multiple sclerosis: longitudinal study of a patient.
Topics: Adult; Aspartic Acid; Axons; Brain; Creatine; Disabled Persons; Humans; Longitudinal Studies; Magnet | 1997 |
A study of multiple sclerosis patients with magnetic resonance spectroscopic imaging.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Female; Humans; Magnetic Reso | 1995 |
Benign versus secondary-progressive multiple sclerosis: the potential role of proton MR spectroscopy in defining the nature of disability.
Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Disease Progression; Female; Follow-Up Studies; Huma | 1998 |
Imaging axonal damage of normal-appearing white matter in multiple sclerosis.
Topics: Aspartic Acid; Axons; Brain; Creatine; Disability Evaluation; Humans; Magnetic Resonance Imaging; Ma | 1998 |
Axonal damage correlates with disability in patients with relapsing-remitting multiple sclerosis. Results of a longitudinal magnetic resonance spectroscopy study.
Topics: Aspartic Acid; Axons; Brain; Creatine; Disability Evaluation; Disease Progression; Humans; Longitudi | 1998 |
Quantitative spectroscopic imaging of the human brain.
Topics: Aspartic Acid; Brain Chemistry; Brain Mapping; Cerebral Ventricles; Choline; Computer Graphics; Crea | 1998 |
Correlates of executive function in multiple sclerosis: the use of magnetic resonance spectroscopy as an index of focal pathology.
Topics: Adult; Analysis of Variance; Aspartic Acid; Attention; Biomarkers; Case-Control Studies; Chi-Square | 1999 |
Absolute quantification of brain metabolites by proton magnetic resonance spectroscopy in normal-appearing white matter of multiple sclerosis patients.
Topics: Adult; Algorithms; Aspartic Acid; Brain; Choline; Creatine; Female; Humans; Magnetic Resonance Imagi | 1999 |
Combined magnetization transfer and proton spectroscopic imaging in the assessment of pathologic brain lesions in multiple sclerosis.
Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Creatine; Female; Humans; Magnetic Resonance Imaging; | 1999 |
In vivo evidence for axonal dysfunction remote from focal cerebral demyelination of the type seen in multiple sclerosis.
Topics: Acute Disease; Adult; Aspartic Acid; Axons; Brain; Creatine; Female; Follow-Up Studies; Humans; Magn | 1999 |
A (1)H magnetic resonance spectroscopy study of aging in parietal white matter: implications for trials in multiple sclerosis.
Topics: Adolescent; Adult; Aged; Aging; Aspartic Acid; Brain Chemistry; Choline; Creatine; Female; Humans; I | 2000 |
Proton magnetic resonance spectroscopy in primary and secondary progressive multiple sclerosis.
Topics: Adult; Aged; Aspartic Acid; Brain; Choline; Creatine; Disease Progression; Female; Humans; Magnetic | 2000 |
Quantitative proton magnetic resonance spectroscopy of focal brain lesions.
Topics: Adolescent; Aspartic Acid; Biomarkers, Tumor; Brain; Brain Abscess; Brain Diseases; Brain Neoplasms; | 2000 |
Axonal damage in multiple sclerosis plaques: a combined magnetic resonance imaging and 1H-magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Aspartic Acid; Axons; Brain; Choline; Creatine; Female; Humans; Lactic Acid; Magn | 2001 |
Evidence of axonal damage in the early stages of multiple sclerosis and its relevance to disability.
Topics: Adult; Aspartic Acid; Atrophy; Axons; Brain; Chromatography, High Pressure Liquid; Creatine; Disabil | 2001 |
Correlates of MS disability assessed in vivo using aggregates of MR quantities.
Topics: Adult; Aspartic Acid; Brain; Creatine; Disability Evaluation; Female; Humans; Magnetic Resonance Ima | 2001 |
Proton magnetic resonance spectroscopic imaging for metabolic characterization of demyelinating plaques.
Topics: Acute Disease; Adult; Aspartic Acid; Biopsy; Brain Chemistry; Brain Neoplasms; Choline; Creatine; De | 1992 |
Proton magnetic resonance spectroscopy for metabolic characterization of plaques in multiple sclerosis.
Topics: Choline; Chronic Disease; Creatine; Humans; Magnetic Resonance Spectroscopy; Multiple Sclerosis; Pro | 1991 |
Human brain proton localized NMR spectroscopy in multiple sclerosis.
Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Female; Humans; Magnetic Resonance | 1991 |
[Significance of plasma creatine and neurologic disorders for the creatine level of cerebrospinal fluid in man].
Topics: Amyotrophic Lateral Sclerosis; Creatine; Dementia; Encephalitis; Epilepsy; Humans; Meningitis; Multi | 1972 |
Studies on myopathy during corticotrophin treatment in multiple sclerosis patients.
Topics: Adrenocorticotropic Hormone; Adult; Creatine; Creatine Kinase; Female; Fructose-Bisphosphate Aldolas | 1967 |