Page last updated: 2024-10-17

creatine and Lupus Erythematosus, Systemic

creatine has been researched along with Lupus Erythematosus, Systemic in 25 studies

Lupus Erythematosus, Systemic: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

Research Excerpts

ExcerptRelevanceReference
"In women with SLE with mild-moderate disease activity, ferritin, oestradiol and uric acid levels at mid-gestation may predict preterm birth."3.79Predictors of preterm birth in patients with mild systemic lupus erythematosus. ( Clowse, ME; Criscione-Schreiber, LG; James, A; Pisetsky, DS; Wallace, DJ; Weisman, M, 2013)
"The N-acetylaspartate-to-creatine/phosphocreatine ratio was smaller in those patients with significant cerebral atrophy (1."3.69Analysis of cerebral structural changes in systemic lupus erythematosus by proton MR spectroscopy. ( Griffey, RH; Hart, BL; Haseler, LJ; Matwiyoff, NA; Sibbitt, RR; Sibbitt, WL, 1994)
"We evaluated retrospectively the effect of superimposed pregnancy upon the course of systemic lupus erythematosus (SLE) in patients receiving glucocorticoids or azathioprine at conception."3.67Pregnancy among patients with systemic lupus erythematosus receiving immunosuppressive therapy. ( Dorsey, JK; Meehan, RT, 1987)
" Additionally, self-reported adverse events were recorded throughout the trial."2.79Efficacy and safety of creatine supplementation in childhood-onset systemic lupus erythematosus: a randomized, double-blind, placebo-controlled, crossover trial. ( de Sá Pinto, AL; Gualano, B; Hayashi, AP; Otaduy, MC; Pereira, RM; Sallum, AM; Sapienza, MT; Silva, CA; Solis, MY, 2014)
"The patient had persistent joint pain and weakness after intravenous methylprednisolone administration and complained of an inability to walk with a positive test for Gower's sign one week after admission, accompanied by elevated alanine aminotransferase (ALT) and creatine-phospho-kinase (CPK) levels."1.72Overlap syndrome in a 12-year-old girl with systemic lupus erythematosus and anti-oj antibody-positive polymyositis: a case report. ( Kao, JK; Lin, KH, 2022)
"Insulin sensitivity was estimated using the homeostatic model assessment index (HOMA-B) for beta cell function and (HOMA-IR) for peripheral tissue insulin resistance."1.39Metabolic syndrome and insulin resistance comorbidity in systemic lupus erythematosus. Effect on carotid intima-media thickness. ( Abdel-Rasheed, E; El-Fishawy, H; Gheita, TA; Nasrallah, MM; Raafat, HA; Sayed, S, 2013)
"Moreover, depression was significantly correlated with titers of autoantibodies against DNA, NMDA receptors and cardiolipin."1.35Depression is an early disease manifestation in lupus-prone MRL/lpr mice. ( Campbell, SR; Cui, MH; Gao, HX; Gulinello, M; Hee-Hwang, J; Putterman, C; Zong, P, 2009)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19907 (28.00)18.7374
1990's5 (20.00)18.2507
2000's7 (28.00)29.6817
2010's4 (16.00)24.3611
2020's2 (8.00)2.80

Authors

AuthorsStudies
Lin, KH1
Kao, JK1
Kilic, H3
Sahin, S3
Toprak, MF3
Hatay, GH3
Yilmaz, K3
Adrovic, A3
Barut, K3
Ozturk Isik, E3
Tuzun, E3
Kizilkilic, O3
Saltik, S3
Kasapcopur, O3
Hayashi, AP1
Solis, MY1
Sapienza, MT1
Otaduy, MC1
de Sá Pinto, AL1
Silva, CA1
Sallum, AM1
Pereira, RM1
Gualano, B1
Gao, HX1
Campbell, SR1
Cui, MH1
Zong, P1
Hee-Hwang, J1
Gulinello, M1
Putterman, C1
Filley, CM2
Kozora, E2
Brown, MS2
Miller, DE2
West, SG2
Arciniegas, DB2
Grimm, A1
Zhang, L2
Pelzman, J1
Gheita, TA1
Raafat, HA1
Sayed, S1
El-Fishawy, H1
Nasrallah, MM1
Abdel-Rasheed, E1
Clowse, ME1
Wallace, DJ1
Weisman, M1
James, A1
Criscione-Schreiber, LG1
Pisetsky, DS1
MACHTEY, I1
POLLAK, VE1
PIRANI, CL1
SCHWARTZ, FD1
Handa, R1
Sahota, P1
Kumar, M1
Jagannathan, NR1
Bal, CS1
Gulati, M1
Tripathi, BM1
Wali, JP1
Appenzeller, S1
Li, LM1
Costallat, LT1
Cendes, F1
Sibbitt, WL4
Haseler, LJ2
Griffey, RH1
Hart, BL1
Sibbitt, RR1
Matwiyoff, NA1
Griffey, RR1
Friedman, SD1
Brooks, WM3
Sabet, A1
Barker, PB1
van Zijl, PC1
Duyn, JH1
Moonen, CT1
Jung, RE1
Ford, CC1
Greinel, EJ1
Kaplanski, G1
Cacoub, P1
Farnarier, C1
Marin, V1
Grégoire, R1
Gatel, A1
Durand, JM1
Harlé, JR1
Bongrand, P1
Piette, JC1
Al-Maini, MH1
Mountz, JD1
Al-Mohri, HA1
El-Ageb, EM1
Al-Riyami, BM1
Svenson, KL1
Zhou, T1
Richens, ER1
Axford, JS1
Howe, FA1
Heron, C1
Griffiths, JR1
Hackshaw, KV1
Voelkel, NF1
Thomas, RB1
Westcott, JY1
Meehan, RT1
Dorsey, JK1
Garcia-Caceres, U1
Ortega, J1
Muth, RG1
Kreysel, H1
Jänner, M1
Wehrmann, R1
Kobayashi, T1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Safety of Creatine Supplementation in Patients With Juvenile Systemic Lupus Erythematosus and Juvenile Dermatomyositis[NCT01217320]40 participants (Anticipated)Interventional2011-01-31Recruiting
Libman-Sacks Endocarditis as a Cause of Neuropsychiatric Systemic Lupus Erythematosus[NCT00858884]68 participants (Actual)Interventional2006-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for creatine and Lupus Erythematosus, Systemic

ArticleYear
Efficacy and safety of creatine supplementation in childhood-onset systemic lupus erythematosus: a randomized, double-blind, placebo-controlled, crossover trial.
    Lupus, 2014, Volume: 23, Issue:14

    Topics: Adolescent; Anaerobic Threshold; Body Composition; Bone Remodeling; Child; Creatine; Cross-Over Stud

2014

Other Studies

24 other studies available for creatine and Lupus Erythematosus, Systemic

ArticleYear
Overlap syndrome in a 12-year-old girl with systemic lupus erythematosus and anti-oj antibody-positive polymyositis: a case report.
    Pediatric rheumatology online journal, 2022, Oct-21, Volume: 20, Issue:1

    Topics: Adult; Alanine Transaminase; Antibodies, Antinuclear; Arthralgia; Autoantibodies; Child; Creatine; C

2022
Assessment of myelin oligodendrocyte glycoprotein antibodies and magnetic resonance spectroscopy in childhood-onset systemic lupus erythematosus.
    Clinical and experimental rheumatology, 2023, Volume: 41, Issue:3

    Topics: Choline; Creatine; Humans; Lupus Erythematosus, Systemic; Lupus Vasculitis, Central Nervous System;

2023
Assessment of myelin oligodendrocyte glycoprotein antibodies and magnetic resonance spectroscopy in childhood-onset systemic lupus erythematosus.
    Clinical and experimental rheumatology, 2023, Volume: 41, Issue:3

    Topics: Choline; Creatine; Humans; Lupus Erythematosus, Systemic; Lupus Vasculitis, Central Nervous System;

2023
Assessment of myelin oligodendrocyte glycoprotein antibodies and magnetic resonance spectroscopy in childhood-onset systemic lupus erythematosus.
    Clinical and experimental rheumatology, 2023, Volume: 41, Issue:3

    Topics: Choline; Creatine; Humans; Lupus Erythematosus, Systemic; Lupus Vasculitis, Central Nervous System;

2023
Assessment of myelin oligodendrocyte glycoprotein antibodies and magnetic resonance spectroscopy in childhood-onset systemic lupus erythematosus.
    Clinical and experimental rheumatology, 2023, Volume: 41, Issue:3

    Topics: Choline; Creatine; Humans; Lupus Erythematosus, Systemic; Lupus Vasculitis, Central Nervous System;

2023
Depression is an early disease manifestation in lupus-prone MRL/lpr mice.
    Journal of neuroimmunology, 2009, Feb-15, Volume: 207, Issue:1-2

    Topics: Animals; Aspartic Acid; Autoantibodies; Brain; Cardiolipins; Choline; Chromatin; Creatine; Depressio

2009
White matter microstructure and cognition in non-neuropsychiatric systemic lupus erythematosus.
    Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology, 2009, Volume: 22, Issue:1

    Topics: Adult; Aspartic Acid; Axons; Brain; Brain Chemistry; Choline; Cognition; Cognition Disorders; Creati

2009
Memory impairment associated with neurometabolic abnormalities of the hippocampus in patients with non-neuropsychiatric systemic lupus erythematosus.
    Lupus, 2011, Volume: 20, Issue:6

    Topics: Adult; Aspartic Acid; Case-Control Studies; Creatine; Female; Glutamic Acid; Hippocampus; Humans; Lu

2011
Metabolic syndrome and insulin resistance comorbidity in systemic lupus erythematosus. Effect on carotid intima-media thickness.
    Zeitschrift fur Rheumatologie, 2013, Volume: 72, Issue:2

    Topics: Adult; Blood Glucose; Carotid Intima-Media Thickness; Comorbidity; Creatine; Female; Humans; Insulin

2013
Predictors of preterm birth in patients with mild systemic lupus erythematosus.
    Annals of the rheumatic diseases, 2013, Sep-01, Volume: 72, Issue:9

    Topics: Adult; Biomarkers; Cohort Studies; Comorbidity; Creatine; Estradiol; Female; Ferritins; Gestational

2013
[DERMATOMYOSITIS].
    Harefuah, 1964, Feb-01, Volume: 66

    Topics: Creatine; Creatinine; Dermatomyositis; Diagnosis, Differential; Electromyography; Humans; Lupus Eryt

1964
THE NATURAL HISTORY OF THE RENAL MANIFESTATIONS OF SYSTEMIC LUPUS ERYTHEMATOSUS.
    The Journal of laboratory and clinical medicine, 1964, Volume: 63

    Topics: Arteries; Black People; Blood Chemical Analysis; Creatine; Creatinine; Glomerulonephritis; Kidney Di

1964
In vivo proton magnetic resonance spectroscopy (MRS) and single photon emission computerized tomography (SPECT) in systemic lupus erythematosus (SLE).
    Magnetic resonance imaging, 2003, Volume: 21, Issue:9

    Topics: Adult; Aspartic Acid; Brain; Cerebrovascular Circulation; Creatine; Female; Humans; Lupus Erythemato

2003
Evidence of reversible axonal dysfunction in systemic lupus erythematosus: a proton MRS study.
    Brain : a journal of neurology, 2005, Volume: 128, Issue:Pt 12

    Topics: Adult; Analysis of Variance; Antibodies, Antiphospholipid; Aspartic Acid; Axons; Biomarkers; Brain;

2005
Analysis of cerebral structural changes in systemic lupus erythematosus by proton MR spectroscopy.
    AJNR. American journal of neuroradiology, 1994, Volume: 15, Issue:5

    Topics: Adolescent; Adult; Aspartic Acid; Atrophy; Brain; Choline; Creatine; Energy Metabolism; Female; Huma

1994
Neurometabolism of active neuropsychiatric lupus determined with proton MR spectroscopy.
    AJNR. American journal of neuroradiology, 1997, Volume: 18, Issue:7

    Topics: Adult; Aspartic Acid; Brain; Brain Damage, Chronic; Brain Ischemia; Brain Mapping; Choline; Creatine

1997
Neurochemistry of brain lesions determined by spectroscopic imaging in systemic lupus erythematosus.
    The Journal of rheumatology, 1997, Volume: 24, Issue:12

    Topics: Adult; Aspartic Acid; Biomarkers; Cerebral Ventricles; Choline; Creatine; Female; Humans; Lactic Aci

1997
Relationship between neurometabolite derangement and neurocognitive dysfunction in systemic lupus erythematosus.
    The Journal of rheumatology, 1999, Volume: 26, Issue:1

    Topics: Adult; Aspartic Acid; Brain; Choline; Cognition Disorders; Creatine; Female; Humans; Lupus Erythemat

1999
Increased soluble vascular cell adhesion molecule 1 concentrations in patients with primary or systemic lupus erythematosus-related antiphospholipid syndrome: correlations with the severity of thrombosis.
    Arthritis and rheumatism, 2000, Volume: 43, Issue:1

    Topics: Adult; Aged; Brain Diseases; Creatine; E-Selectin; Female; Humans; Intercellular Adhesion Molecule-1

2000
Serum levels of soluble Fas correlate with indices of organ damage in systemic lupus erythematosus.
    Lupus, 2000, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Alanine Transaminase; Apoptosis; Arabs; Aspartate Aminotransferases; Biomarkers;

2000
Sensitivity of quantitative (1)H magnetic resonance spectroscopy of the brain in detecting early neuronal damage in systemic lupus erythematosus.
    Annals of the rheumatic diseases, 2001, Volume: 60, Issue:2

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Diseases; Case-Control Studies; Choline; Creatine; Fem

2001
Urine leukotriene E4 levels are elevated in patients with active systemic lupus erythematosus.
    The Journal of rheumatology, 1992, Volume: 19, Issue:2

    Topics: Adult; Arthritis, Rheumatoid; Creatine; Female; Humans; Leukotriene E4; Lupus Erythematosus, Systemi

1992
Pregnancy among patients with systemic lupus erythematosus receiving immunosuppressive therapy.
    The Journal of rheumatology, 1987, Volume: 14, Issue:2

    Topics: Azathioprine; Creatine; Female; Fertilization; Humans; Immunosuppression Therapy; Lupus Erythematosu

1987
Studies of tubular alterations in diffuse renal disease. II. Quantitative evaluation of cellularity and length of proximal convoluted tubules in the kidney of lupus nephritis.
    The American journal of pathology, 1967, Volume: 50, Issue:6

    Topics: Albuminuria; Blood Urea Nitrogen; Cell Nucleus; Creatine; Humans; Hypertrophy; Kidney Tubules; Lupus

1967
Diuretic properties of furosemide in renal disease.
    Annals of internal medicine, 1968, Volume: 69, Issue:2

    Topics: Acid-Base Equilibrium; Adolescent; Adult; Aged; Amyloidosis; Blood Urea Nitrogen; Creatine; Diabetic

1968
[Creatine metabolism disorders in dermatomyositis, progressive scleroderma, visceral and cutaneous lupus erythematosus and panarteritis bodosa].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1968, Volume: 19, Issue:9

    Topics: Adolescent; Adult; Amyloidosis; Collagen Diseases; Creatine; Creatinine; Dermatomyositis; Female; Hu

1968
[Transition and complications of SLE and related diseases].
    Nihon rinsho. Japanese journal of clinical medicine, 1968, Volume: 26, Issue:12

    Topics: Adrenal Cortex Hormones; Adult; Creatine; Creatinine; Dermatomyositis; Female; Humans; Lupus Erythem

1968