creatine has been researched along with Insulin Resistance in 21 studies
Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " It included experimental studies that investigated the effects of creatine supplementation on diabetes treatment or prevention and its relationship with fasting blood glucose and insulin resistance." | 9.22 | Does creatine supplementation improve glycemic control and insulin resistance in healthy and diabetic patients? A systematic review and meta-analysis. ( Delpino, FM; Figueiredo, LM, 2022) |
| "The effect of creatine supplementation, alone or in combination with exercise training, on insulin sensitivity, intramyocellular lipid content (IMCL) and fatty acid translocase (FAT)/CD36 content was investigated in rats fed a sucrose-rich cafeteria diet during 12 weeks." | 7.77 | Exercise-induced, but not creatine-induced, decrease in intramyocellular lipid content improves insulin sensitivity in rats. ( De Bock, K; Eijnde, BO; Hespel, P; Szlufcik, K; Vaisy, M; Van Proeyen, K; Van Veldhoven, P; Verbeke, K, 2011) |
| "Insulin resistance was measured by the homeostatic measure of insulin resistance (HOMA-IR)." | 5.72 | Association of muscle mass measured by D3-Creatine (D3Cr), sarcopenic obesity, and insulin-glucose homeostasis in postmenopausal women. ( Banack, HR; Evans, WJ; LaMonte, MJ; Manson, JE; Shankaran, M; Wactawski-Wende, J; Zhu, K, 2022) |
| " It included experimental studies that investigated the effects of creatine supplementation on diabetes treatment or prevention and its relationship with fasting blood glucose and insulin resistance." | 5.22 | Does creatine supplementation improve glycemic control and insulin resistance in healthy and diabetic patients? A systematic review and meta-analysis. ( Delpino, FM; Figueiredo, LM, 2022) |
| "We aimed to investigate the possible role of creatine (CR) supplementation in counteracting dexamethasone-induced muscle wasting and insulin resistance in rats." | 3.78 | Effects of creatine supplementation on muscle wasting and glucose homeostasis in rats treated with dexamethasone. ( Brum, PC; da Luz, CR; de Moraes, WM; de Salles Painelli, V; de Salvi Guimarães, F; dos Santos Costa, A; Gualano, B; Lancha, AH; Medeiros, A; Nicastro, H, 2012) |
| "The effect of creatine supplementation, alone or in combination with exercise training, on insulin sensitivity, intramyocellular lipid content (IMCL) and fatty acid translocase (FAT)/CD36 content was investigated in rats fed a sucrose-rich cafeteria diet during 12 weeks." | 3.77 | Exercise-induced, but not creatine-induced, decrease in intramyocellular lipid content improves insulin sensitivity in rats. ( De Bock, K; Eijnde, BO; Hespel, P; Szlufcik, K; Vaisy, M; Van Proeyen, K; Van Veldhoven, P; Verbeke, K, 2011) |
| "3-Guanidinopropionic acid (1) has been demonstrated both to improve insulin sensitivity and to promote weight loss selectively from adipose tissue in animal models of non-insulin-dependent diabetes mellitus (NIDDM)." | 3.71 | Synthesis and biological activity of aminoguanidine and diaminoguanidine analogues of the antidiabetic/antiobesity agent 3-guanidinopropionic acid. ( Burr, JE; Connell, MA; Cudahy, MM; Evans, BR; Fisher, PV; Larsen, SD; May, PD; Meglasson, MD; Robinson, DD; Stevens, FC; Tanis, SP; Tucker, JA; Vaillancourt, VA; Vidmar, TJ; Yu, JH, 2001) |
| "In absence of HIV infection, or concomitant treatment, short-term exposure to T20 or RAL in healthy adult volunteers did not lead to any indicative changes in toxicity markers thus presuming the safe profile of both drugs." | 2.90 | Metabolic, mitochondrial, renal and hepatic safety of enfuvirtide and raltegravir antiretroviral administration: Randomized crossover clinical trial in healthy volunteers. ( Arnaiz, JA; Barroso, S; Blanco, JL; Carné, X; Garrabou, G; Gatell, JM; González-Segura, À; Larousse, M; Lazzari, E; Llopis, J; Loncà, M; Mallolas, J; Manriquez, M; Martínez, E; Miró, O; Morén, C; Riba, N; Santana, G, 2019) |
| "Insulin resistance was measured by the homeostatic measure of insulin resistance (HOMA-IR)." | 1.72 | Association of muscle mass measured by D3-Creatine (D3Cr), sarcopenic obesity, and insulin-glucose homeostasis in postmenopausal women. ( Banack, HR; Evans, WJ; LaMonte, MJ; Manson, JE; Shankaran, M; Wactawski-Wende, J; Zhu, K, 2022) |
| "The study outcome was incident type 2 diabetes, defined as a fasting plasma glucose ≥7." | 1.62 | Plasma creatine and incident type 2 diabetes in a general population-based cohort: The PREVEND study. ( Bakker, SJL; Connelly, MA; de Boer, RA; Douwes, RM; Dullaart, RPF; Flores-Guerrero, JL; Franssen, CFM; Garcia, E; Groothof, D; Kema, IP; Post, A; Schutten, JC; Swarte, JC; Wallimann, T, 2021) |
| "Insulin sensitivity was estimated using the homeostatic model assessment index (HOMA-B) for beta cell function and (HOMA-IR) for peripheral tissue insulin resistance." | 1.39 | Metabolic syndrome and insulin resistance comorbidity in systemic lupus erythematosus. Effect on carotid intima-media thickness. ( Abdel-Rasheed, E; El-Fishawy, H; Gheita, TA; Nasrallah, MM; Raafat, HA; Sayed, S, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 10 (47.62) | 24.3611 |
| 2020's | 5 (23.81) | 2.80 |
| Authors | Studies |
|---|---|
| Vaillancourt, VA | 1 |
| Larsen, SD | 1 |
| Tanis, SP | 1 |
| Burr, JE | 1 |
| Connell, MA | 1 |
| Cudahy, MM | 1 |
| Evans, BR | 1 |
| Fisher, PV | 1 |
| May, PD | 1 |
| Meglasson, MD | 1 |
| Robinson, DD | 1 |
| Stevens, FC | 1 |
| Tucker, JA | 1 |
| Vidmar, TJ | 1 |
| Yu, JH | 1 |
| Delpino, FM | 1 |
| Figueiredo, LM | 1 |
| Banack, HR | 2 |
| LaMonte, MJ | 2 |
| Manson, JE | 2 |
| Zhu, K | 2 |
| Evans, WJ | 2 |
| Shankaran, M | 2 |
| Wactawski-Wende, J | 2 |
| Khan, SH | 1 |
| Shahid, R | 1 |
| Fazal, N | 1 |
| Ijaz, A | 1 |
| Oliveira, CLP | 1 |
| Antunes, BMM | 1 |
| Gomes, AC | 1 |
| Lira, FS | 1 |
| Pimentel, GD | 1 |
| Boulé, NG | 1 |
| Mota, JF | 1 |
| Post, A | 1 |
| Groothof, D | 1 |
| Schutten, JC | 1 |
| Flores-Guerrero, JL | 1 |
| Swarte, JC | 1 |
| Douwes, RM | 1 |
| Kema, IP | 1 |
| de Boer, RA | 1 |
| Garcia, E | 1 |
| Connelly, MA | 1 |
| Wallimann, T | 1 |
| Dullaart, RPF | 1 |
| Franssen, CFM | 1 |
| Bakker, SJL | 1 |
| Solis, MY | 1 |
| Artioli, GG | 1 |
| Gualano, B | 2 |
| Barroso, S | 1 |
| Morén, C | 1 |
| González-Segura, À | 1 |
| Riba, N | 1 |
| Arnaiz, JA | 1 |
| Manriquez, M | 1 |
| Santana, G | 1 |
| Blanco, JL | 1 |
| Larousse, M | 1 |
| Loncà, M | 1 |
| Lazzari, E | 1 |
| Llopis, J | 1 |
| Mallolas, J | 1 |
| Miró, O | 1 |
| Carné, X | 1 |
| Gatell, JM | 1 |
| Garrabou, G | 1 |
| Martínez, E | 1 |
| Fried, PJ | 1 |
| Pascual-Leone, A | 1 |
| Bolo, NR | 1 |
| Yeh, WJ | 1 |
| Yang, HY | 1 |
| Chen, JR | 1 |
| Forbes, SC | 1 |
| Sletten, N | 1 |
| Durrer, C | 1 |
| Myette-Côté, É | 1 |
| Candow, D | 1 |
| Little, JP | 1 |
| Hespel, P | 2 |
| Derave, W | 1 |
| Zhao, LC | 1 |
| Zhang, XD | 1 |
| Liao, SX | 1 |
| Gao, HC | 1 |
| Wang, HY | 1 |
| Lin, DH | 1 |
| Vaisy, M | 1 |
| Szlufcik, K | 1 |
| De Bock, K | 1 |
| Eijnde, BO | 1 |
| Van Proeyen, K | 1 |
| Verbeke, K | 1 |
| Van Veldhoven, P | 1 |
| Nicastro, H | 1 |
| de Moraes, WM | 1 |
| de Salles Painelli, V | 1 |
| da Luz, CR | 1 |
| dos Santos Costa, A | 1 |
| de Salvi Guimarães, F | 1 |
| Medeiros, A | 1 |
| Brum, PC | 1 |
| Lancha, AH | 1 |
| Saccà, F | 1 |
| Quarantelli, M | 1 |
| Rinaldi, C | 1 |
| Tucci, T | 1 |
| Piro, R | 1 |
| Perrotta, G | 1 |
| Carotenuto, B | 1 |
| Marsili, A | 1 |
| Palma, V | 1 |
| De Michele, G | 1 |
| Brunetti, A | 1 |
| Brescia Morra, V | 1 |
| Filla, A | 1 |
| Salvatore, M | 1 |
| Gheita, TA | 1 |
| Raafat, HA | 1 |
| Sayed, S | 1 |
| El-Fishawy, H | 1 |
| Nasrallah, MM | 1 |
| Abdel-Rasheed, E | 1 |
| Thirunavukkarasu, V | 1 |
| Anitha Nandhini, AT | 1 |
| Anuradha, CV | 1 |
| Cloarec, O | 1 |
| Dumas, ME | 1 |
| Craig, A | 1 |
| Barton, RH | 1 |
| Trygg, J | 1 |
| Hudson, J | 1 |
| Blancher, C | 1 |
| Gauguier, D | 1 |
| Lindon, JC | 1 |
| Holmes, E | 1 |
| Nicholson, J | 1 |
| Kim, CS | 1 |
| Sohn, EJ | 1 |
| Kim, YS | 1 |
| Jung, DH | 1 |
| Jang, DS | 1 |
| Lee, YM | 1 |
| Kim, DH | 1 |
| Kim, JS | 1 |
| Levine, LS | 1 |
| Sonenberg, M | 1 |
| New, MI | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Patient Centric Motor Neuron Disease Activities of Daily Living Scale[NCT02852278] | 410 participants (Actual) | Observational | 2016-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for creatine and Insulin Resistance
| Article | Year |
|---|---|
Does creatine supplementation improve glycemic control and insulin resistance in healthy and diabetic patients? A systematic review and meta-analysis.
Topics: Blood Glucose; Creatine; Diabetes Mellitus; Dietary Supplements; Glycemic Control; Humans; Insulin R | 2022 |
Potential of Creatine in Glucose Management and Diabetes.
Topics: Animals; Creatine; Diabetes Mellitus, Type 2; Dietary Supplements; Exercise; Glucose; Glucose Transp | 2021 |
Ergogenic effects of creatine in sports and rehabilitation.
Topics: Administration, Oral; Anabolic Agents; Athletic Performance; Creatine; Exercise; Gene Expression Reg | 2007 |
4 trials available for creatine and Insulin Resistance
| Article | Year |
|---|---|
Creatine supplementation does not promote additional effects on inflammation and insulin resistance in older adults: A pilot randomized, double-blind, placebo-controlled trial.
Topics: Aged; Body Composition; Creatine; Dietary Supplements; Humans; Inflammation; Insulin Resistance; Mus | 2020 |
Metabolic, mitochondrial, renal and hepatic safety of enfuvirtide and raltegravir antiretroviral administration: Randomized crossover clinical trial in healthy volunteers.
Topics: Adult; Alanine Transaminase; Anti-Retroviral Agents; Creatine; Enfuvirtide; Healthy Volunteers; HIV | 2019 |
Creatine Monohydrate Supplementation Does Not Augment Fitness, Performance, or Body Composition Adaptations in Response to Four Weeks of High-Intensity Interval Training in Young Females.
Topics: Adaptation, Physiological; Adult; Body Composition; Cardiorespiratory Fitness; Creatine; Dietary Sup | 2017 |
A randomized controlled clinical trial of growth hormone in amyotrophic lateral sclerosis: clinical, neuroimaging, and hormonal results.
Topics: Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Arginine; Choline; Creatine; Double-B | 2012 |
14 other studies available for creatine and Insulin Resistance
| Article | Year |
|---|---|
Synthesis and biological activity of aminoguanidine and diaminoguanidine analogues of the antidiabetic/antiobesity agent 3-guanidinopropionic acid.
Topics: Acetates; Animals; Blood Glucose; Carrier Proteins; Cell Line; Creatine; Creatine Kinase; Guanidines | 2001 |
Association of muscle mass measured by D3-Creatine (D3Cr), sarcopenic obesity, and insulin-glucose homeostasis in postmenopausal women.
Topics: Blood Glucose; Body Mass Index; Creatine; Female; Humans; Insulin; Insulin Resistance; Insulin, Regu | 2022 |
Association of muscle mass measured by D3-Creatine (D3Cr), sarcopenic obesity, and insulin-glucose homeostasis in postmenopausal women.
Topics: Blood Glucose; Body Mass Index; Creatine; Female; Humans; Insulin; Insulin Resistance; Insulin, Regu | 2022 |
Association of muscle mass measured by D3-Creatine (D3Cr), sarcopenic obesity, and insulin-glucose homeostasis in postmenopausal women.
Topics: Blood Glucose; Body Mass Index; Creatine; Female; Humans; Insulin; Insulin Resistance; Insulin, Regu | 2022 |
Association of muscle mass measured by D3-Creatine (D3Cr), sarcopenic obesity, and insulin-glucose homeostasis in postmenopausal women.
Topics: Blood Glucose; Body Mass Index; Creatine; Female; Humans; Insulin; Insulin Resistance; Insulin, Regu | 2022 |
Comparison of Various Abdominal Obesity Measures for Predicting Metabolic Syndrome, Diabetes, Nephropathy, and Dyslipidemia.
Topics: Anthropometry; Body Mass Index; Creatine; Cross-Sectional Studies; Dyslipidemias; Female; Humans; In | 2019 |
Plasma creatine and incident type 2 diabetes in a general population-based cohort: The PREVEND study.
Topics: Blood Glucose; Creatine; Diabetes Mellitus, Type 2; Female; Humans; Insulin Resistance; Male; Middle | 2021 |
Diabetes and the link between neuroplasticity and glutamate in the aging human motor cortex.
Topics: Aged; Aged, 80 and over; Aging; Aspartic Acid; Creatine; Diabetes Mellitus, Type 2; Female; Glucose; | 2019 |
Soy β-conglycinin retards progression of diabetic nephropathy via modulating the insulin sensitivity and angiotensin-converting enzyme activity in rats fed with high salt diet.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antigens, Plant; Blood Glucose; Creatine; Diabeti | 2014 |
A metabonomic comparison of urinary changes in Zucker and GK rats.
Topics: Acids, Acyclic; Animals; Biomarkers; Creatine; Diabetes Mellitus, Type 2; Dimethylamines; Disease Mo | 2010 |
Exercise-induced, but not creatine-induced, decrease in intramyocellular lipid content improves insulin sensitivity in rats.
Topics: Animals; Blood Glucose; Creatine; Dietary Fats; Insulin; Insulin Resistance; Lipid Metabolism; Male; | 2011 |
Effects of creatine supplementation on muscle wasting and glucose homeostasis in rats treated with dexamethasone.
Topics: Animals; Blood Glucose; Creatine; Dexamethasone; Drinking Water; Glucose Transporter Type 4; Humans; | 2012 |
Metabolic syndrome and insulin resistance comorbidity in systemic lupus erythematosus. Effect on carotid intima-media thickness.
Topics: Adult; Blood Glucose; Carotid Intima-Media Thickness; Comorbidity; Creatine; Female; Humans; Insulin | 2013 |
Lipoic acid attenuates hypertension and improves insulin sensitivity, kallikrein activity and nitrite levels in high fructose-fed rats.
Topics: Animals; Biological Transport; Blood Glucose; Blood Pressure; Calcium-Transporting ATPases; Creatine | 2004 |
Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets.
Topics: Amines; Animals; Biomarkers; Citric Acid; Creatine; Creatinine; Dietary Carbohydrates; Discriminant | 2005 |
Effects of KIOM-79 on hyperglycemia and diabetic nephropathy in type 2 diabetic Goto-Kakizaki rats.
Topics: Administration, Oral; Animals; Blood Glucose; Collagen Type IV; Creatine; Diabetes Mellitus, Experim | 2007 |
Metabolic effects in children of a 37 amino acid fragment of bovine growth hormone.
Topics: Adenoma, Chromophobe; Adolescent; Alkaline Phosphatase; Amino Acids; Blood Urea Nitrogen; Calcium; C | 1973 |