creatine has been researched along with Hepatic Encephalopathy in 20 studies
Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)
Excerpt | Relevance | Reference |
---|---|---|
" Hepatic encephalopathy (HE) is characterized by abnormal cerebral metabolites, yet the response to lactulose and other anti-HE measures is still primarily determined by using arbitrary categorical clinical rating scales, rather than MR spectroscopy." | 7.70 | Proton MR spectroscopic measurement of neurometabolites in hepatic encephalopathy during oral lactulose therapy. ( Agarwal, VP; Haseler, LJ; McCarthy, DM; Mojtahedzadeh, HN; Reddy, S; Sibbitt, WL, 1998) |
" Among a number of clinical and laboratory variables analyzed, the only independent predictive factors of overt HE were hyponatremia (serum sodium < 130 mEq / l), history of overt HE, serum bilirubin,and serum creatinine." | 3.75 | Hyponatremia is a risk factor of hepatic encephalopathy in patients with cirrhosis: a prospective study with time-dependent analysis. ( Arroyo, V; Baccaro, ME; Ginès, P; Gómez-Ansón, B; Guevara, M; Martín-Llahí, M; Monté-Rubio, GC; Rami, L; Ríos, J; Torre, A; Torres, F, 2009) |
" Hepatic encephalopathy (HE) is characterized by abnormal cerebral metabolites, yet the response to lactulose and other anti-HE measures is still primarily determined by using arbitrary categorical clinical rating scales, rather than MR spectroscopy." | 3.70 | Proton MR spectroscopic measurement of neurometabolites in hepatic encephalopathy during oral lactulose therapy. ( Agarwal, VP; Haseler, LJ; McCarthy, DM; Mojtahedzadeh, HN; Reddy, S; Sibbitt, WL, 1998) |
"Brain alterations such as hepatic encephalopathy or brain edema are usually associated with liver failure." | 2.50 | Magnetic resonance of the brain in chronic and acute liver failure. ( Chavarria, L; Cordoba, J, 2014) |
"The sequence of events in hepatic encephalopathy (HE) remains unclear." | 1.51 | Longitudinal neurometabolic changes in the hippocampus of a rat model of chronic hepatic encephalopathy. ( Braissant, O; Cudalbu, C; Grosse, J; McLin, VA; Pierzchala, K; Rackayová, V, 2019) |
"Hepatic encephalopathy is associated with a regional specific decrease of GABA levels in the visual cortex, while no changes were revealed for the sensorimotor cortex." | 1.42 | Low visual cortex GABA levels in hepatic encephalopathy: links to blood ammonia, critical flicker frequency, and brain osmolytes. ( Baumgarten, TJ; Butz, M; Hoogenboom, N; Oeltzschner, G; Schnitzler, A; Wittsack, HJ, 2015) |
"To develop a reliable surgical model of acute hepatic failure and hyperammonemia in rats that avoids porto-systemic shunt and bile duct ligation, applicable to hepatic encephalopathy research." | 1.36 | A new experimental model for acute hepatic failure in rats. ( Bellodi-Privato, M; D'Albuquerque, LA; Kubrusly, MS; Leite, KR; Machado, MC; Molan, NT; Teixeira, AR, 2010) |
"Cerebral edema is present in patients with MHE." | 1.36 | Effect of surgical portosystemic shunt on prevalence of minimal hepatic encephalopathy in children with extrahepatic portal venous obstruction: assessment by magnetic resonance imaging and psychometry. ( Gupta, RK; Lal, R; Saraswat, VA; Srivastava, A; Thomas, MA; Yachha, SK; Yadav, SK, 2010) |
"Acute-on-chronic liver failure (ACLF), acute liver failure (ALF) and chronic liver disease (CLD) are common forms of liver failure and present with similar clinical profiles." | 1.35 | In vivo 1H magnetic resonance spectroscopy-derived metabolite variations between acute-on-chronic liver failure and acute liver failure. ( Gupta, RK; Nath, K; Radha Krishna, Y; Saraswat, VA; Thomas, MA; Verma, A, 2008) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (15.00) | 18.2507 |
2000's | 6 (30.00) | 29.6817 |
2010's | 10 (50.00) | 24.3611 |
2020's | 1 (5.00) | 2.80 |
Authors | Studies |
---|---|
Asaki, Y | 1 |
Murofushi, Y | 1 |
Yasukawa, K | 1 |
Hara, M | 1 |
Takanashi, JI | 1 |
Braissant, O | 1 |
Rackayová, V | 1 |
Pierzchala, K | 1 |
Grosse, J | 1 |
McLin, VA | 1 |
Cudalbu, C | 1 |
Chavarria, L | 1 |
Cordoba, J | 1 |
Razek, AA | 1 |
Abdalla, A | 1 |
Ezzat, A | 1 |
Megahed, A | 1 |
Barakat, T | 1 |
Meng, LP | 1 |
Chen, YC | 1 |
Li, YH | 1 |
Zhu, JS | 1 |
Ye, JL | 1 |
Oeltzschner, G | 2 |
Butz, M | 2 |
Baumgarten, TJ | 1 |
Hoogenboom, N | 1 |
Wittsack, HJ | 2 |
Schnitzler, A | 2 |
Wickrath, F | 1 |
Guevara, M | 1 |
Baccaro, ME | 1 |
Torre, A | 1 |
Gómez-Ansón, B | 1 |
Ríos, J | 1 |
Torres, F | 1 |
Rami, L | 1 |
Monté-Rubio, GC | 1 |
Martín-Llahí, M | 1 |
Arroyo, V | 1 |
Ginès, P | 1 |
Singhal, A | 1 |
Nagarajan, R | 1 |
Kumar, R | 1 |
Huda, A | 1 |
Gupta, RK | 4 |
Thomas, MA | 4 |
Teixeira, AR | 1 |
Machado, MC | 1 |
Kubrusly, MS | 1 |
Molan, NT | 1 |
Bellodi-Privato, M | 1 |
Leite, KR | 1 |
D'Albuquerque, LA | 1 |
Herman-Sucharska, I | 1 |
Grzybek, M | 1 |
Grochowska, A | 1 |
Karcz, P | 1 |
Urbanik, A | 1 |
Srivastava, A | 1 |
Yadav, SK | 1 |
Lal, R | 1 |
Yachha, SK | 1 |
Saraswat, VA | 3 |
Bokemeyer, M | 1 |
Ding, XQ | 1 |
Goldbecker, A | 1 |
Raab, P | 2 |
Heeren, M | 1 |
Arvanitis, D | 1 |
Tillmann, HL | 1 |
Lanfermann, H | 1 |
Weissenborn, K | 1 |
Saksena, S | 1 |
Rai, V | 1 |
Rathore, RS | 1 |
Purwar, A | 1 |
Kumar, M | 1 |
Verma, A | 1 |
Radha Krishna, Y | 1 |
Nath, K | 1 |
Danielsen, ER | 1 |
Michaelis, T | 1 |
Ross, BD | 1 |
Laubenberger, J | 1 |
Bayer, S | 1 |
Thiel, T | 1 |
Hennig, J | 1 |
Langer, M | 1 |
Haseler, LJ | 1 |
Sibbitt, WL | 1 |
Mojtahedzadeh, HN | 1 |
Reddy, S | 1 |
Agarwal, VP | 1 |
McCarthy, DM | 1 |
Naegele, T | 1 |
Grodd, W | 1 |
Viebahn, R | 1 |
Seeger, U | 1 |
Klose, U | 1 |
Seitz, D | 1 |
Kaiser, S | 1 |
Mader, I | 1 |
Mayer, J | 1 |
Lauchart, W | 1 |
Gregor, M | 1 |
Voigt, K | 1 |
Delcker, A | 1 |
Turowski, B | 1 |
Mihm, U | 1 |
Rusch, O | 1 |
Pilatus, U | 1 |
Zeuzem, S | 1 |
Zanella, FE | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Role of Magnetic Resonance Imaging in Detection of Minimal Hepatic Encephalopathy[NCT04131205] | 40 participants (Anticipated) | Observational | 2019-06-01 | Recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 review available for creatine and Hepatic Encephalopathy
Article | Year |
---|---|
Magnetic resonance of the brain in chronic and acute liver failure.
Topics: Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Brain Edema; Choline; Creatine; Glutamic Acid; Gl | 2014 |
1 trial available for creatine and Hepatic Encephalopathy
Article | Year |
---|---|
Minimal hepatic encephalopathy in children with liver cirrhosis: diffusion-weighted MR imaging and proton MR spectroscopy of the brain.
Topics: Adolescent; Child; Choline; Creatine; Diffusion Magnetic Resonance Imaging; Female; Glutamic Acid; H | 2014 |
18 other studies available for creatine and Hepatic Encephalopathy
Article | Year |
---|---|
Neurochemistry of hyponatremic encephalopathy evaluated by MR spectroscopy.
Topics: Aspartic Acid; Child; Creatine; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Humans; Hyponatrem | 2020 |
Longitudinal neurometabolic changes in the hippocampus of a rat model of chronic hepatic encephalopathy.
Topics: Ammonium Compounds; Animals; Ascorbic Acid; Astrocytes; Chronic Disease; Creatine; Disease Models, A | 2019 |
Viability assessment of magnetic resonance spectroscopy for the detection of minimal hepatic encephalopathy severity.
Topics: Adult; Aspartic Acid; Basal Ganglia; Brain; Cognition; Creatine; Female; Glutamic Acid; Glutamine; G | 2015 |
Low visual cortex GABA levels in hepatic encephalopathy: links to blood ammonia, critical flicker frequency, and brain osmolytes.
Topics: Ammonia; Brain Chemistry; Creatine; Female; Flicker Fusion; gamma-Aminobutyric Acid; Glutamine; Glyc | 2015 |
Covert hepatic encephalopathy: elevated total glutathione and absence of brain water content changes.
Topics: Aged; Ammonia; Brain; Brain Edema; Creatine; Female; Glutathione; Hepatic Encephalopathy; Humans; Ma | 2016 |
Hyponatremia is a risk factor of hepatic encephalopathy in patients with cirrhosis: a prospective study with time-dependent analysis.
Topics: Adult; Aged; Aspartic Acid; Bilirubin; Brain Chemistry; Creatine; Creatinine; Female; Follow-Up Stud | 2009 |
Magnetic resonance T2-relaxometry and 2D L-correlated spectroscopy in patients with minimal hepatic encephalopathy.
Topics: Adult; Aged; Brain; Choline; Creatine; Female; Hepatic Encephalopathy; Humans; Inositol; Liver; Magn | 2009 |
A new experimental model for acute hepatic failure in rats.
Topics: Ammonia; Animals; Bilirubin; Creatine; Disease Models, Animal; Hepatectomy; Hepatic Encephalopathy; | 2010 |
[Myoinositol trends in HMRS brain spectrum of patients with hepatic encephalopathy].
Topics: Ammonia; Biomarkers; Choline; Creatine; Hepatic Encephalopathy; Humans; Inositol; Liver; Magnetic Re | 2010 |
Effect of surgical portosystemic shunt on prevalence of minimal hepatic encephalopathy in children with extrahepatic portal venous obstruction: assessment by magnetic resonance imaging and psychometry.
Topics: Adolescent; Ammonia; Brain Edema; Child; Creatine; Cross-Sectional Studies; Female; Glutamine; Hepat | 2010 |
Evidence for neuroinflammation and neuroprotection in HCV infection-associated encephalopathy.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Mapping; Case-Control Studies; Choline; Cognition Disorders | 2011 |
Cerebral diffusion tensor imaging and in vivo proton magnetic resonance spectroscopy in patients with fulminant hepatic failure.
Topics: Adolescent; Adult; Anisotropy; Aspartic Acid; Biomarkers; Case-Control Studies; Cerebrovascular Circ | 2008 |
In vivo 1H magnetic resonance spectroscopy-derived metabolite variations between acute-on-chronic liver failure and acute liver failure.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Case-Control Studies; Choline; Chronic Disease; Creat | 2008 |
Three methods of calibration in quantitative proton MR spectroscopy.
Topics: Adult; Aspartic Acid; Body Water; Brain; Brain Chemistry; Brain Injuries; Calibration; Choline; Crea | 1995 |
[Clinical uses of proton magnetic resonance spectroscopy of the brain].
Topics: AIDS Dementia Complex; Alzheimer Disease; Animals; Aspartic Acid; Brain; Brain Diseases; Brain Disea | 1998 |
Proton MR spectroscopic measurement of neurometabolites in hepatic encephalopathy during oral lactulose therapy.
Topics: Administration, Oral; Adult; Brain; Choline; Creatine; Glutamic Acid; Glutamine; Hepatic Encephalopa | 1998 |
MR imaging and (1)H spectroscopy of brain metabolites in hepatic encephalopathy: time-course of renormalization after liver transplantation.
Topics: Adult; Basal Ganglia; Choline; Creatine; Energy Metabolism; Female; Glutamic Acid; Glutamine; Hepati | 2000 |
Proton MR spectroscopy of neurometabolites in hepatic encephalopathy during L-ornithine-L-aspartate treatment--results of a pilot study.
Topics: Aged; Brain; Creatine; Dipeptides; Female; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Humans; | 2002 |