creatine has been researched along with Glial Cell Tumors in 125 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "We performed serial (1)H-MRSI examinations to assess intratumoral metabolite intensities in 16 patients receiving high-dose oral tamoxifen monotherapy for recurrent malignant glioma (WHO grade III or IV) as part of a phase II clinical trial." | 9.13 | Prospective serial proton MR spectroscopic assessment of response to tamoxifen for recurrent malignant glioma. ( Arnold, DL; Assina, R; Caramanos, Z; Langleben, A; Leblanc, R; Preul, MC; Sankar, T; Villemure, JG, 2008) |
| "This study was designed to evaluate proton magnetic resonance spectroscopy ((1)H-MRS) for monitoring the WHO grade II glioma (low-grade glioma (LGG)) treated with temozolomide (TMZ)." | 7.77 | Predicting the outcome of grade II glioma treated with temozolomide using proton magnetic resonance spectroscopy. ( Abud, L; Capelle, L; Chiras, J; Costalat, R; De Marco, G; Guillevin, R; Habas, C; Hoang-Xuan, K; Menuel, C; Taillibert, S; Vallée, JN, 2011) |
| "PURPOSE Our purpose was to evaluate cerebral glioma grade by using normal side creatine (Cr) as an internal reference in multi-voxel 1H-MR spectroscopy." | 7.74 | Evaluation of cerebral glioma grade by using normal side creatine as an internal reference in multi-voxel 1H-MR spectroscopy. ( Ağildere, AM; Atalay, B; Elhan, AH; Geyik, E; Ozen, O; Yerli, H, 2007) |
| " Considering that brain energy metabolism is possibly altered in MSUD, the objective of this study was to determine creatine kinase (CK) activity, a key enzyme of energy homeostasis, in C6 glioma cells exposed to BCKA." | 7.73 | Creatine and antioxidant treatment prevent the inhibition of creatine kinase activity and the morphological alterations of C6 glioma cells induced by the branched-chain alpha-keto acids accumulating in maple syrup urine disease. ( Funchal, C; Gottfried, C; Jacques-Silva, MC; Pessoa-Pureur, R; Santos, AQ; Schuck, PF; Wajner, M, 2006) |
| "Creatine (Cr) is a major metabolite in the bioenergetic system." | 5.46 | Creatine CEST MRI for Differentiating Gliomas with Different Degrees of Aggressiveness. ( Cai, K; Damen, FC; Hariharan, H; Poptani, H; Reddy, R; Scotti, AM; Tain, RW; Zhou, XJ, 2017) |
| "We performed serial (1)H-MRSI examinations to assess intratumoral metabolite intensities in 16 patients receiving high-dose oral tamoxifen monotherapy for recurrent malignant glioma (WHO grade III or IV) as part of a phase II clinical trial." | 5.13 | Prospective serial proton MR spectroscopic assessment of response to tamoxifen for recurrent malignant glioma. ( Arnold, DL; Assina, R; Caramanos, Z; Langleben, A; Leblanc, R; Preul, MC; Sankar, T; Villemure, JG, 2008) |
| " There are a number of metabolites that can be identified by standard brain proton MRS but only a few of them has a clinical significance in diagnosis of gliomas including N-acetylaspartate, choline, creatine, myo-inositol, lactate, and lipids." | 4.89 | Potential of MR spectroscopy for assessment of glioma grading. ( Bulik, M; Jancalek, R; Mechl, M; Skoch, A; Vanicek, J, 2013) |
| "Age and choline/creatine ratio are strong independent prognostic factors in high grade gliomas." | 3.81 | Prognostic Value of MRS Metabolites in Postoperative Irradiated High Grade Gliomas. ( Kelekis, N; Kokakis, I; Kouloulias, V; Kouvaris, JR; Kyrgias, G; Mosa, E; Papathanasiou, M; Pissakas, G; Pistevou-Gombaki, K; Tolia, M; Tsoukalas, N; Verganelakis, D, 2015) |
| "There is significant elevation of the choline (Cho) /creatine (Cr) ratio, Cho peak and depression of the N-acetylaspartate (NAA) peak in gliomas." | 3.78 | Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas. ( Shang, HB; Zhang, WF; Zhao, WG, 2012) |
| "This study was designed to evaluate proton magnetic resonance spectroscopy ((1)H-MRS) for monitoring the WHO grade II glioma (low-grade glioma (LGG)) treated with temozolomide (TMZ)." | 3.77 | Predicting the outcome of grade II glioma treated with temozolomide using proton magnetic resonance spectroscopy. ( Abud, L; Capelle, L; Chiras, J; Costalat, R; De Marco, G; Guillevin, R; Habas, C; Hoang-Xuan, K; Menuel, C; Taillibert, S; Vallée, JN, 2011) |
| "Our purpose was to investigate whether in vivo proton magnetic resonance spectroscopic imaging, using normalized concentrations of total choline (tCho) and total creatine (tCr), can differentiate between WHO grade I pilocytic astrocytoma (PA) and diffuse, fibrillary WHO grade II astrocytoma (DA) in children." | 3.76 | Proton magnetic resonance spectroscopic imaging in pediatric low-grade gliomas. ( Franz, K; Hattingen, E; Kieslich, M; Lehrbecher, T; Pilatus, U; Porto, L, 2010) |
| "PURPOSE Our purpose was to evaluate cerebral glioma grade by using normal side creatine (Cr) as an internal reference in multi-voxel 1H-MR spectroscopy." | 3.74 | Evaluation of cerebral glioma grade by using normal side creatine as an internal reference in multi-voxel 1H-MR spectroscopy. ( Ağildere, AM; Atalay, B; Elhan, AH; Geyik, E; Ozen, O; Yerli, H, 2007) |
| "In vivo magnetic resonance spectroscopy (MRS) studies of glial brain tumours reported that higher grade of astrocytoma is associated with increased level of choline-containing compounds (Cho) and decreased levels of N-acetylaspartate (NAA) and creatine and phosphocreatine (Cr)." | 3.73 | In vitro study of astrocytic tumour metabolism by proton magnetic resonance spectroscopy. ( Belan, V; Béres, A; De Riggo, J; Dobrota, D; Galanda, M; Likavcanová, K; Liptaj, T; Mlynárik, V; Prónayová, N, 2005) |
| " Considering that brain energy metabolism is possibly altered in MSUD, the objective of this study was to determine creatine kinase (CK) activity, a key enzyme of energy homeostasis, in C6 glioma cells exposed to BCKA." | 3.73 | Creatine and antioxidant treatment prevent the inhibition of creatine kinase activity and the morphological alterations of C6 glioma cells induced by the branched-chain alpha-keto acids accumulating in maple syrup urine disease. ( Funchal, C; Gottfried, C; Jacques-Silva, MC; Pessoa-Pureur, R; Santos, AQ; Schuck, PF; Wajner, M, 2006) |
| "Diffusion tensor imaging (DTI) and MR spectroscopy are noninvasive, quantitative tools for the preoperative assessment of gliomas with which the quantitative parameter fractional anisotropy (FA) and the concentration of neurometabolites N-acetylaspartate (NAA), choline (Cho), creatine (Cr) of the brain can be determined." | 3.73 | Disarrangement of fiber tracts and decline of neuronal density correlate in glioma patients--a combined diffusion tensor imaging and 1H-MR spectroscopy study. ( Ding, XQ; Fiehler, J; Goebell, E; Hagel, C; Heese, O; Kucinski, T; Nietz, S; Paustenbach, S; Westphal, M; Zeumer, H, 2006) |
| " The concentration of taurine (Tau) in medulloblastomas was 29." | 3.72 | In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard. ( Harada, K; Houkin, K; Tong, Z; Yamaki, T, 2004) |
| " MRS of normal brain parenchyma displays 4 main metabolites: N-acetyl aspartate (neuronal marker), creatine (cellular density marker), choline (membrane activity marker) and myoinositol (glial marker); pathological processes lead to variations of the level of these metabolites and/or the appearance of abnormal metabolites (lactate), following different patterns according to pathological process involved: glioma, meningioma, metastasis, bacterial or toxoplasmic abscess, radionecrosis." | 3.71 | [Contribution of magnetic resonance spectrometry to the diagnosis of intracranial tumors]. ( Confort-Gouny, S; Cozzone, PJ; Dufour, H; Galanaud, D; Le Fur, Y; Nicoli, F; Peragut, JC; Ranjeva, JP; Roche, P; Viout, P, 2002) |
| " Non-neoplastic lesions such as cerebral infarctions and brain abscesses are marked by decreases in choline (Cho), creatine (Cr) and N-acetyl-aspartate (NAA), while tumours generally have elevated Cho and decreased levels of Cr and NAA." | 3.71 | Clinical application of proton magnetic resonance spectroscopy in the diagnosis of intracranial mass lesions. ( Herminghaus, S; Krings, T; Lanfermann, H; Marquardt, G; Möller-Hartmann, W; Pilatus, U; Zanella, FE, 2002) |
| " Spectroscopy is a reliable technique for grading of gliomas when N-acetyl-aspartate/choline and choline/creatine ratios and presence of lipids are used in combination." | 3.69 | Characterization of intracranial mass lesions with in vivo proton MR spectroscopy. ( Chhabra, DK; Gupta, RK; Jain, VK; Pandey, R; Poptani, H; Roy, R, 1995) |
| " The NAA (N-acetylaspartate)/Cho (choline) ratio of Grade 2 astrocytoma was higher than that of Grade 4." | 3.69 | Non-invasive characterization of brain tumor by in-vivo proton magnetic resonance spectroscopy. ( Bandou, K; Harada, M; Kannuki, S; Miyoshi, H; Nishitani, H; Tanouchi, M, 1995) |
| "(a) Hamartomas showed higher N-acetyl aspartate/creatine, creatine/choline, and N-acetyl aspartate/choline ratios than gliomas." | 3.69 | Proton MR spectroscopy in patients with neurofibromatosis type 1: evaluation of hamartomas and clinical correlation. ( Castillo, M; Green, C; Greenwood, R; Kwock, L; Schiro, S; Smith, K; Wilson, D, 1995) |
| " We used proton nuclear magnetic resonance spectroscopy to detect the presence of simple metabolites (such as lactic acid, creatine/phosphocreatine, N-acetyl aspartate, and the "choline" pool) in extracts of a human glioma grown subcutaneously in athymic ("nu/nu") mice." | 3.69 | Effects of therapy on the 1H NMR spectrum of a human glioma line. ( Cazzaniga, S; Charles, HC; Schold, SC; Sostman, HD, 1994) |
| "There were no significant adverse effects from FLT injected at a dose of 0." | 2.73 | NCI-sponsored trial for the evaluation of safety and preliminary efficacy of FLT as a marker of proliferation in patients with recurrent gliomas: safety studies. ( Eary, JF; Hoffman, JM; Krohn, KA; Link, JM; Muzi, M; Spence, AM, 2008) |
| "Creatine (Cr) is a major metabolite in the bioenergetic system." | 1.46 | Creatine CEST MRI for Differentiating Gliomas with Different Degrees of Aggressiveness. ( Cai, K; Damen, FC; Hariharan, H; Poptani, H; Reddy, R; Scotti, AM; Tain, RW; Zhou, XJ, 2017) |
| "Glioma is one of the most common types of brain tumors." | 1.46 | Assessment of alterations in X-ray irradiation-induced DNA damage of glioma cells by using proton nuclear magnetic resonance spectroscopy. ( Li, F; Li, H; Shi, W; Xu, Y; Yi, C; Zeng, Q, 2017) |
| "Glioma is the most common type of the primary CNS tumor." | 1.43 | Noninvasive evaluation of radiation-enhanced glioma cells invasiveness by ultra-high-field (1)H-MRS in vitro. ( Cui, Y; Li, FY; Li, HX; Shi, WQ; Wang, JZ; Xu, YJ; Zeng, QS, 2016) |
| "Monofocal acute inflammatory demyelination (MAID), which is observable by CT and MRI as a well-enhanced mass lesion with prominent perifocal edema, is very similar to malignant gliomas radiologically, making differential diagnosis of the two pathologies difficult." | 1.37 | Metabolic assessment of monofocal acute inflammatory demyelination using MR spectroscopy and (11)C-methionine-, (11)C-choline-, and (18)F-fluorodeoxyglucose-PET. ( Aki, T; Asano, Y; Ito, T; Iwama, T; Miwa, K; Shinoda, J; Takenaka, S; Yokoyama, K, 2011) |
| "Most of the brain tumors were characterized by strongly reduced total N-acetylaspartyl compounds and marked increases of myo-inositol and choline-containing compounds, consistent with a lack of neuroaxonal tissue and a proliferation of glial cells." | 1.31 | Quantitative proton magnetic resonance spectroscopy of focal brain lesions. ( Dechent, P; Frahm, J; Hanefeld, F; Herms, J; Markakis, E; Maxton, C; Wilken, B, 2000) |
| "High-grade brain tumors are known to have a high rate of glucose (Glc) consumption." | 1.31 | High glycolytic activity in rat glioma demonstrated in vivo by correlation peak 1H magnetic resonance imaging. ( Décorps, M; Rémy, C; von Kienlin , M; Ziegler, A, 2001) |
| "Seventeen brain tumors were measured by 1H-CSI (chemical shift imaging) in a 1." | 1.30 | Evaluation of metabolic heterogeneity in brain tumors using 1H-chemical shift imaging method. ( Furuya, S; Ide, M; Kizu, O; Maeda, T; Morishita, H; Naruse, S; Ueda, S, 1997) |
| "Higher grades of brain tumors in this study were associated with higher Cho/reference and lower NAA/reference values." | 1.29 | Noninvasive evaluation of malignancy of brain tumors with proton MR spectroscopy. ( Arai, N; Fujiwara, S; Hara, K; Kayama, T; Kumabe, T; Ono, Y; Sato, K; Shimizu, H; Tominaga, T; Yoshimoto, T, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.80) | 18.7374 |
| 1990's | 20 (16.00) | 18.2507 |
| 2000's | 53 (42.40) | 29.6817 |
| 2010's | 42 (33.60) | 24.3611 |
| 2020's | 9 (7.20) | 2.80 |
| Authors | Studies |
|---|---|
| Rudnay, M | 1 |
| Waczulikova, I | 1 |
| Bullova, A | 1 |
| Rjaskova, G | 1 |
| Chorvath, M | 1 |
| Jezberova, M | 1 |
| Lehotska, V | 1 |
| Wang, MH | 1 |
| Roa, W | 1 |
| Wachowicz, K | 1 |
| Yahya, A | 1 |
| Murtha, A | 1 |
| Amanie, J | 1 |
| Chainey, J | 1 |
| Quon, H | 1 |
| Ghosh, S | 1 |
| Patel, S | 1 |
| Tran, D | 3 |
| Nguyen, DH | 3 |
| Nguyen, HK | 3 |
| Nguyen-Thanh, VA | 3 |
| Dong-Van, H | 3 |
| Nguyen, MD | 3 |
| De Stefano, FA | 1 |
| Morell, AA | 1 |
| Smith, G | 1 |
| Warner, T | 1 |
| Soldozy, S | 1 |
| Elarjani, T | 1 |
| Eichberg, DG | 1 |
| Luther, E | 1 |
| Komotar, RJ | 1 |
| Qiao, J | 1 |
| Wu, H | 1 |
| Liu, J | 1 |
| Kang, H | 1 |
| Wang, S | 1 |
| Fang, J | 1 |
| Zhang, J | 3 |
| Zhang, W | 1 |
| Goryawala, M | 1 |
| Saraf-Lavi, E | 1 |
| Nagornaya, N | 1 |
| Heros, D | 1 |
| Komotar, R | 1 |
| Maudsley, AA | 1 |
| Fujita, Y | 1 |
| Kohta, M | 1 |
| Sasayama, T | 1 |
| Tanaka, K | 1 |
| Hashiguchi, M | 1 |
| Nagashima, H | 1 |
| Kyotani, K | 1 |
| Nakai, T | 1 |
| Ito, T | 2 |
| Kohmura, E | 1 |
| Wang, AP | 1 |
| Suryavanshi, T | 1 |
| Marcucci, M | 1 |
| Fong, C | 1 |
| Whitton, AC | 1 |
| Reddy, KKV | 1 |
| Alirezaei, Z | 1 |
| Amouheidari, A | 1 |
| Hassanpour, M | 1 |
| Davanian, F | 1 |
| Iraji, S | 1 |
| Shokrani, P | 1 |
| Nazem-Zadeh, MR | 1 |
| Ditter, P | 1 |
| Hattingen, E | 7 |
| Liu, Z | 1 |
| Berrington, A | 1 |
| Voets, NL | 1 |
| Larkin, SJ | 1 |
| de Pennington, N | 1 |
| Mccullagh, J | 1 |
| Stacey, R | 1 |
| Schofield, CJ | 1 |
| Jezzard, P | 1 |
| Clare, S | 1 |
| Cadoux-Hudson, T | 1 |
| Plaha, P | 1 |
| Ansorge, O | 1 |
| Emir, UE | 1 |
| Gao, W | 2 |
| Wang, X | 2 |
| Li, F | 5 |
| Shi, W | 4 |
| Li, H | 4 |
| Zeng, Q | 5 |
| Pedrosa de Barros, N | 1 |
| Meier, R | 1 |
| Pletscher, M | 1 |
| Stettler, S | 1 |
| Knecht, U | 1 |
| Herrmann, E | 1 |
| Schucht, P | 1 |
| Reyes, M | 1 |
| Gralla, J | 1 |
| Wiest, R | 1 |
| Slotboom, J | 1 |
| Cui, Y | 2 |
| Balos, DR | 1 |
| Gavrilović, S | 1 |
| Lavrnić, S | 1 |
| Vasić, B | 1 |
| Macvanski, M | 1 |
| Damjanović, D | 1 |
| Opinćal, TS | 1 |
| Roder, C | 1 |
| Skardelly, M | 1 |
| Ramina, KF | 1 |
| Beschorner, R | 1 |
| Honneger, J | 1 |
| Nägele, T | 1 |
| Tatagiba, MS | 1 |
| Ernemann, U | 1 |
| Bisdas, S | 1 |
| Bradac, O | 1 |
| Vrana, J | 1 |
| Jiru, F | 1 |
| Kramar, F | 1 |
| Netuka, D | 1 |
| Hrabal, P | 1 |
| Horinek, D | 1 |
| de Lacy, P | 1 |
| Benes, V | 1 |
| Madan, A | 1 |
| Ganji, SK | 2 |
| An, Z | 1 |
| Choe, KS | 1 |
| Pinho, MC | 1 |
| Bachoo, RM | 2 |
| Maher, EM | 1 |
| Choi, C | 2 |
| Babourina-Brooks, B | 1 |
| Wilson, M | 1 |
| Arvanitis, TN | 1 |
| Peet, AC | 1 |
| Davies, NP | 1 |
| Stadler, KL | 1 |
| Ober, CP | 1 |
| Feeney, DA | 1 |
| Jessen, CR | 1 |
| Yamamoto, T | 1 |
| Isobe, T | 1 |
| Akutsu, H | 1 |
| Masumoto, T | 1 |
| Ando, H | 1 |
| Sato, E | 1 |
| Takada, K | 1 |
| Anno, I | 1 |
| Matsumura, A | 1 |
| Ranjith, G | 1 |
| Parvathy, R | 1 |
| Vikas, V | 1 |
| Chandrasekharan, K | 1 |
| Nair, S | 1 |
| Ghasemi, K | 1 |
| Khanmohammadi, M | 1 |
| Saligheh Rad, H | 1 |
| Tolia, M | 1 |
| Verganelakis, D | 1 |
| Tsoukalas, N | 1 |
| Kyrgias, G | 1 |
| Papathanasiou, M | 1 |
| Mosa, E | 1 |
| Kokakis, I | 1 |
| Kouvaris, JR | 1 |
| Pissakas, G | 1 |
| Pistevou-Gombaki, K | 1 |
| Kelekis, N | 1 |
| Kouloulias, V | 1 |
| Wang, Q | 1 |
| Zhang, H | 1 |
| Wu, C | 1 |
| Zhu, W | 1 |
| Chen, X | 1 |
| Xu, B | 1 |
| Carrera, I | 1 |
| Richter, H | 1 |
| Beckmann, K | 1 |
| Meier, D | 1 |
| Dennler, M | 1 |
| Kircher, PR | 1 |
| Xu, YJ | 1 |
| Li, HX | 1 |
| Shi, WQ | 1 |
| Li, FY | 1 |
| Wang, JZ | 1 |
| Zeng, QS | 2 |
| Cai, K | 1 |
| Tain, RW | 1 |
| Zhou, XJ | 1 |
| Damen, FC | 1 |
| Scotti, AM | 1 |
| Hariharan, H | 1 |
| Poptani, H | 2 |
| Reddy, R | 1 |
| Roldan-Valadez, E | 1 |
| Rios, C | 1 |
| Motola-Kuba, D | 1 |
| Matus-Santos, J | 1 |
| Villa, AR | 1 |
| Moreno-Jimenez, S | 1 |
| Xu, Y | 2 |
| Yi, C | 1 |
| Raab, P | 2 |
| Franz, K | 5 |
| Lanfermann, H | 5 |
| Setzer, M | 1 |
| Gerlach, R | 2 |
| Zanella, FE | 3 |
| Pilatus, U | 7 |
| Spence, AM | 1 |
| Muzi, M | 1 |
| Link, JM | 1 |
| Hoffman, JM | 1 |
| Eary, JF | 1 |
| Krohn, KA | 1 |
| Sankar, T | 1 |
| Caramanos, Z | 1 |
| Assina, R | 1 |
| Villemure, JG | 1 |
| Leblanc, R | 1 |
| Langleben, A | 1 |
| Arnold, DL | 2 |
| Preul, MC | 1 |
| Li, Y | 1 |
| Srinivasan, R | 1 |
| Ratiney, H | 1 |
| Lu, Y | 2 |
| Chang, SM | 2 |
| Nelson, SJ | 4 |
| Douis, H | 1 |
| Jafri, M | 1 |
| Sherlala, K | 1 |
| Delic, O | 1 |
| Blamek, S | 1 |
| Larysz, D | 1 |
| Ficek, K | 1 |
| Sokół, M | 2 |
| Miszczyk, L | 1 |
| Tarnawski, R | 1 |
| Senft, C | 1 |
| Schänzer, A | 1 |
| Seifert, V | 1 |
| Gasser, T | 1 |
| Matsusue, E | 1 |
| Fink, JR | 1 |
| Rockhill, JK | 1 |
| Ogawa, T | 1 |
| Maravilla, KR | 1 |
| Goenka, AH | 1 |
| Kumar, A | 1 |
| Sharma, R | 1 |
| Server, A | 2 |
| Josefsen, R | 2 |
| Kulle, B | 2 |
| Maehlen, J | 1 |
| Schellhorn, T | 1 |
| Gadmar, Ø | 1 |
| Kumar, T | 2 |
| Haakonsen, M | 1 |
| Langberg, CW | 1 |
| Nakstad, PH | 2 |
| Gadmar, ØB | 1 |
| Liu, H | 2 |
| Zhang, K | 2 |
| Li, C | 1 |
| Zhou, G | 1 |
| Widhalm, G | 1 |
| Krssak, M | 1 |
| Minchev, G | 1 |
| Wöhrer, A | 1 |
| Traub-Weidinger, T | 1 |
| Czech, T | 1 |
| Asenbaum, S | 1 |
| Marosi, C | 1 |
| Knosp, E | 1 |
| Hainfellner, JA | 1 |
| Prayer, D | 1 |
| Wolfsberger, S | 1 |
| Porto, L | 2 |
| Kieslich, M | 2 |
| Lehrbecher, T | 1 |
| Wagner, M | 1 |
| Nafe, R | 1 |
| Jurcoane, A | 1 |
| Rieger, J | 1 |
| Steinbach, JP | 1 |
| Takenaka, S | 1 |
| Shinoda, J | 1 |
| Asano, Y | 1 |
| Aki, T | 1 |
| Miwa, K | 1 |
| Yokoyama, K | 1 |
| Iwama, T | 1 |
| Guillevin, R | 1 |
| Menuel, C | 1 |
| Taillibert, S | 1 |
| Capelle, L | 1 |
| Costalat, R | 1 |
| Abud, L | 1 |
| Habas, C | 1 |
| De Marco, G | 1 |
| Hoang-Xuan, K | 1 |
| Chiras, J | 1 |
| Vallée, JN | 1 |
| Amin, A | 1 |
| Moustafa, H | 1 |
| Ahmed, E | 1 |
| El-Toukhy, M | 1 |
| DeBerardinis, RJ | 1 |
| Hatanpaa, KJ | 1 |
| Rakheja, D | 1 |
| Kovacs, Z | 1 |
| Yang, XL | 1 |
| Mashimo, T | 1 |
| Raisanen, JM | 1 |
| Marin-Valencia, I | 1 |
| Pascual, JM | 1 |
| Madden, CJ | 1 |
| Mickey, BE | 1 |
| Malloy, CR | 1 |
| Maher, EA | 1 |
| Nicolasjilwan, M | 1 |
| Lopes, MB | 1 |
| Larner, J | 1 |
| Wintermark, M | 1 |
| Schiff, D | 1 |
| Steffen-Smith, EA | 1 |
| Venzon, DJ | 1 |
| Bent, RS | 1 |
| Hipp, SJ | 1 |
| Warren, KE | 1 |
| Mertens, K | 1 |
| Acou, M | 1 |
| Van den Broecke, C | 1 |
| Nuyts, R | 1 |
| Van Roost, D | 1 |
| Achten, E | 1 |
| Goethals, I | 1 |
| Shang, HB | 1 |
| Zhao, WG | 1 |
| Zhang, WF | 1 |
| Bulik, M | 1 |
| Jancalek, R | 1 |
| Vanicek, J | 1 |
| Skoch, A | 1 |
| Mechl, M | 1 |
| Caivano, R | 1 |
| Lotumolo, A | 1 |
| Rabasco, P | 1 |
| Zandolino, A | 1 |
| D'Antuono, F | 1 |
| Villonio, A | 1 |
| Lancellotti, MI | 1 |
| Macarini, L | 1 |
| Cammarota, A | 1 |
| Saindane, AM | 1 |
| Cha, S | 4 |
| Law, M | 2 |
| Xue, X | 1 |
| Knopp, EA | 2 |
| Zagzag, D | 1 |
| Rock, JP | 2 |
| Hearshen, D | 2 |
| Scarpace, L | 2 |
| Croteau, D | 2 |
| Gutierrez, J | 2 |
| Fisher, JL | 2 |
| Rosenblum, ML | 1 |
| Mikkelsen, T | 2 |
| Bulakbasi, N | 2 |
| Kocaoglu, M | 2 |
| Ors, F | 1 |
| Tayfun, C | 2 |
| Uçöz, T | 1 |
| Galanaud, D | 1 |
| Nicoli, F | 1 |
| Le Fur, Y | 1 |
| Roche, P | 1 |
| Confort-Gouny, S | 1 |
| Dufour, H | 1 |
| Ranjeva, JP | 1 |
| Peragut, JC | 1 |
| Viout, P | 1 |
| Cozzone, PJ | 1 |
| Simonetti, AW | 1 |
| Melssen, WJ | 1 |
| van der Graaf, M | 1 |
| Postma, GJ | 1 |
| Heerschap, A | 2 |
| Buydens, LM | 1 |
| Lee, MC | 1 |
| Pirzkall, A | 2 |
| McKnight, TR | 4 |
| Ando, K | 1 |
| Ishikura, R | 1 |
| Nagami, Y | 1 |
| Morikawa, T | 1 |
| Takada, Y | 1 |
| Ikeda, J | 1 |
| Nakao, N | 1 |
| Matsumoto, T | 1 |
| Arita, N | 1 |
| Chiang, IC | 1 |
| Kuo, YT | 1 |
| Lu, CY | 1 |
| Yeung, KW | 1 |
| Lin, WC | 1 |
| Sheu, FO | 1 |
| Liu, GC | 1 |
| Chen, CY | 1 |
| Lirng, JF | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| NCI-Sponsored Trial for the Evaluation of Safety and Preliminary Efficacy Using [F18] Fluorothymidine (FLT) As a Marker of Proliferation in Patients With Primary Brain Tumors[NCT00276770] | 12 participants (Actual) | Interventional | 2006-02-28 | Completed | |||
| Multi-paramEtric Imaging to Assess Treatment REsponse After Stereotactic Radiosurgery of Brain Metastases[NCT04626206] | 12 participants (Anticipated) | Observational | 2020-12-31 | Not yet recruiting | |||
| Treatment Development of Triheptanoin for Glucose Transporter Type I Deficiency[NCT02021526] | Phase 1/Phase 2 | 0 participants (Actual) | Interventional | 2015-12-31 | Withdrawn (stopped due to NIH funding resulted in new clinical trial) | ||
| Metabolic Characterization of Space Occupying Lesions of the Brain Using in Vivo MR- (Spectroscopic) Imaging at 3 Tesla and 7 Tesla[NCT04233788] | 55 participants (Anticipated) | Observational | 2021-09-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for creatine and Glial Cell Tumors
| Article | Year |
|---|---|
Unique magnetic resonance spectroscopy profile of intracranial meningiomas compared to gliomas: a systematic review.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Female; Glioma; Humans; Magnetic Resonance Spectr | 2023 |
The diagnostic performance of magnetic resonance spectroscopy in differentiating high-from low-grade gliomas: A systematic review and meta-analysis.
Topics: Area Under Curve; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Databases, Factual; Glioma; Hum | 2016 |
Potential of MR spectroscopy for assessment of glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Humans; Inositol; Lactates; Lipid Metabol | 2013 |
3 Tesla magnetic resonance spectroscopy: cerebral gliomas vs. metastatic brain tumors. Our experience and review of the literature.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Diagnosis, Differ | 2013 |
Proton magnetic resonance spectroscopic evaluation of brain tumor metabolism.
Topics: Alanine; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Glutamic Acid; Glutamine; Humans | 2004 |
Brain stem involvement in children with neurofibromatosis type 1: role of magnetic resonance imaging and spectroscopy in the distinction from diffuse pontine glioma.
Topics: Adolescent; Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Child, Preschool; Choline; Creatine; | 1997 |
Anaerobic energy metabolism in brain tumors.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aerobiosis; Anaerobiosis; An | 1972 |
8 trials available for creatine and Glial Cell Tumors
| Article | Year |
|---|---|
Evaluation of human glioma using in-vivo proton magnetic resonance spectroscopy combined with expression of cyclooxygenase-2: a preliminary clinical trial.
Topics: Adult; Aged; Biomarkers, Tumor; Brain; Brain Neoplasms; Choline; Creatine; Cyclooxygenase 2; Female; | 2017 |
NCI-sponsored trial for the evaluation of safety and preliminary efficacy of FLT as a marker of proliferation in patients with recurrent gliomas: safety studies.
Topics: Adult; Biomarkers; Carbon Dioxide; Cell Proliferation; Creatine; Dideoxynucleosides; Drug-Related Si | 2008 |
Prospective serial proton MR spectroscopic assessment of response to tamoxifen for recurrent malignant glioma.
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Dis | 2008 |
Distinction between high-grade gliomas and solitary metastases using peritumoral 3-T magnetic resonance spectroscopy, diffusion, and perfusion imagings.
Topics: Adult; Aged; Aspartic Acid; Blood Volume; Brain; Brain Neoplasms; Cerebrovascular Circulation; Choli | 2004 |
Contrast/Noise ratio on conventional MRI and choline/creatine ratio on proton MRI spectroscopy accurately discriminate low-grade from high-grade cerebral gliomas.
Topics: Adolescent; Adult; Aged; Algorithms; Brain Neoplasms; Child; Child, Preschool; Choline; Creatine; Fe | 2006 |
Correlation of magnetic resonance spectroscopic and growth characteristics within Grades II and III gliomas.
Topics: Antibodies, Antinuclear; Antibodies, Monoclonal; Apoptosis; Aspartic Acid; Brain Neoplasms; Cell Pro | 2007 |
Multivoxel 3D proton MR spectroscopy in the distinction of recurrent glioma from radiation injury.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Fema | 2007 |
Proton magnetic resonance spectroscopy in patients with glial tumors: a multicenter study.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Astrocytoma; Brain; Brain Neoplasms; Child; Child, Pr | 1996 |
110 other studies available for creatine and Glial Cell Tumors
| Article | Year |
|---|---|
Magnetic resonance spectroscopy - its added value in brain glioma multiparametric assessment.
Topics: Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Glioma; Humans; Magnetic Resonance Spectro | 2021 |
Early Metabolic Changes in 1H-MRSI Predictive for Survival in Patients With Newly Diagnosed High-grade Glioma.
Topics: Brain Neoplasms; Choline; Creatine; Glioma; Humans; Magnetic Resonance Imaging; Magnetic Resonance S | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Spectral Analysis Based on Hemodynamic Habitat Imaging Predicts Isocitrate Dehydrogenase Status and Prognosis in High-Grade Glioma.
Topics: Brain Neoplasms; Creatine; Glioma; Hemodynamics; Humans; Isocitrate Dehydrogenase; Magnetic Resonanc | 2023 |
The Association between Whole-Brain MR Spectroscopy and IDH Mutation Status in Gliomas.
Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Female; Glioma; Humans; Isocitrate | 2020 |
Intraoperative 3-T Magnetic Resonance Spectroscopy for Detection of Proliferative Remnants of Glioma.
Topics: Adult; Aged; Aged, 80 and over; Brain; Brain Neoplasms; Choline; Creatine; Female; Glioma; Humans; M | 2020 |
Radiation Necrosis Following Stereotactic Radiosurgery for Trigeminal Neuralgia.
Topics: Aged, 80 and over; Aspartic Acid; Brain Diseases; Brain Neoplasms; Choline; Creatine; Diagnostic Err | 2020 |
Early Detection of Radiation-Induced Injury and Prediction of Cognitive Deficit by MRS Metabolites in Radiotherapy of Low-Grade Glioma.
Topics: Adolescent; Adult; Aspartic Acid; Brain Neoplasms; Cognitive Dysfunction; Creatine; Early Diagnosis; | 2021 |
[Magnetic resonance spectroscopy of brain tumors].
Topics: Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Glioma; Humans; Magnetic Resonance Imaging | 2017 |
Age, choline-to-N-acetyl aspartate, and lipids-lactate-to-creatine ratios assemble a significant Cox's proportional-hazards regression model for survival prediction in patients with high-grade gliomas.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Humans; Lactic Acid; Lipids; Magnetic Res | 2017 |
A comparison of 2-hydroxyglutarate detection at 3 and 7 T with long-TE semi-LASER.
Topics: Adult; Brain Neoplasms; Choline; Creatine; Female; Glioma; Glutarates; Humans; Isocitrate Dehydrogen | 2018 |
Cho/Cr ratio at MR spectroscopy as a biomarker for cellular proliferation activity and prognosis in glioma: correlation with the expression of minichromosome maintenance protein 2.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biomarkers; Brain; Brain Neoplasms; Cell Proliferation; Chil | 2019 |
On the relation between MR spectroscopy features and the distance to MRI-visible solid tumor in GBM patients.
Topics: Algorithms; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Glioma; Healthy Volunteers; Hu | 2018 |
Measuring the lactate-to-creatine ratio via
Topics: Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Creatine; DNA Damage; Electrop | 2018 |
Proton magnetic resonance spectroscopy and apparent diffusion coefficient in evaluation of solid brain lesions.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Child; Choline; Creatine; Diffusion | 2013 |
Spectroscopy imaging in intraoperative MR suite: tissue characterization and optimization of tumor resection.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Female; Glioma; Humans; Image | 2014 |
Recognition of anaplastic foci within low-grade gliomas using MR spectroscopy.
Topics: Adult; Aged; Biopsy; Brain Neoplasms; Creatine; Glioma; Humans; Magnetic Resonance Spectroscopy; Mid | 2014 |
Proton T2 measurement and quantification of lactate in brain tumors by MRS at 3 Tesla in vivo.
Topics: Adult; Aged; Artifacts; Aspartic Acid; Brain Chemistry; Brain Neoplasms; Choline; Creatine; Female; | 2015 |
MRS water resonance frequency in childhood brain tumours: a novel potential biomarker of temperature and tumour environment.
Topics: Adolescent; Algorithms; Biomarkers, Tumor; Body Water; Brain Neoplasms; Cerebellar Neoplasms; Child; | 2014 |
Multivoxel proton magnetic resonance spectroscopy of inflammatory and neoplastic lesions of the canine brain at 3.0 T.
Topics: Analysis of Variance; Animals; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Diagnosis, | 2014 |
Influence of echo time in quantitative proton MR spectroscopy using LCModel.
Topics: Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Glioma; Humans; Image Processing, Computer | 2015 |
Machine learning methods for the classification of gliomas: Initial results using features extracted from MR spectroscopy.
Topics: Algorithms; Artificial Intelligence; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Cre | 2015 |
Accurate grading of brain gliomas by soft independent modeling of class analogy based on non-negative matrix factorization of proton magnetic resonance spectra.
Topics: Algorithms; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Glycine; Humans; Neoplasm Gra | 2016 |
Prognostic Value of MRS Metabolites in Postoperative Irradiated High Grade Gliomas.
Topics: Adult; Age Factors; Aged; Choline; Creatine; Disease-Free Survival; Female; Glioma; Humans; Magnetic | 2015 |
Evaluation of intracranial neoplasia and noninfectious meningoencephalitis in dogs by use of short echo time, single voxel proton magnetic resonance spectroscopy at 3.0 Tesla.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Case-Control Studies; Creatine; Dog Diseases; Dogs; Female; | 2016 |
Noninvasive evaluation of radiation-enhanced glioma cells invasiveness by ultra-high-field (1)H-MRS in vitro.
Topics: Aspartic Acid; Brain Neoplasms; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Choline; C | 2016 |
Creatine CEST MRI for Differentiating Gliomas with Different Degrees of Aggressiveness.
Topics: Animals; Brain Neoplasms; Cell Differentiation; Creatine; Glioma; Image Processing, Computer-Assiste | 2017 |
Choline-to-N-acetyl aspartate and lipids-lactate-to-creatine ratios together with age assemble a significant Cox's proportional-hazards regression model for prediction of survival in high-grade gliomas.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Biomarkers; Brain Neoplasms; Choline; Cre | 2016 |
Assessment of alterations in X-ray irradiation-induced DNA damage of glioma cells by using proton nuclear magnetic resonance spectroscopy.
Topics: Apoptosis; Astrocytes; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Choline; Creati | 2017 |
Prognostic value of choline and creatine in WHO grade II gliomas.
Topics: Adult; Aged; Brain Neoplasms; Choline; Creatine; Disease-Free Survival; Female; Follow-Up Studies; G | 2008 |
Comparison of T(1) and T(2) metabolite relaxation times in glioma and normal brain at 3T.
Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Female; Gliom | 2008 |
Bilateral thalamic glioma.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Female; Glioma; Humans; Magnetic Resonance Imagin | 2008 |
(1)H MRSI and progression-free survival in patients with WHO grades II and III gliomas.
Topics: Adult; Aged; Brain Neoplasms; Choline; Creatine; Disease Progression; Disease-Free Survival; Female; | 2010 |
MR spectroscopic evaluation of brain tissue damage after treatment for pediatric brain tumors.
Topics: Adolescent; Aspartic Acid; Brain; Brain Neoplasms; Child; Choline; Creatine; Ependymoma; Female; Gli | 2010 |
Diagnostic value of proton magnetic resonance spectroscopy in the noninvasive grading of solid gliomas: comparison of maximum and mean choline values.
Topics: Adult; Brain Neoplasms; Choline; Creatine; Glioma; Humans; Image Processing, Computer-Assisted; Magn | 2009 |
Distinction between glioma progression and post-radiation change by combined physiologic MR imaging.
Topics: Adult; Aspartic Acid; Blood Volume; Brain; Brain Neoplasms; Cerebrovascular Circulation; Choline; Cr | 2010 |
MR spectroscopy for differentiation of recurrent glioma from radiation-induced changes.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Neoplasms; Child; Child, Preschool; Choline; Contrast | 2009 |
Proton magnetic resonance spectroscopy in the distinction of high-grade cerebral gliomas from single metastatic brain tumors.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Biomarkers; Brain Neoplasms; Choline; Contrast Media; | 2010 |
Measurements of diagnostic examination performance using quantitative apparent diffusion coefficient and proton MR spectroscopic imaging in the preoperative evaluation of tumor grade in cerebral gliomas.
Topics: Area Under Curve; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Diffusion Magnetic Resonance Im | 2011 |
Noninvasive evaluation of cerebral glioma grade by using multivoxel 3D proton MR spectroscopy.
Topics: Adult; Aged; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Creatine; Female; Glioma; H | 2011 |
Value of 1H-magnetic resonance spectroscopy chemical shift imaging for detection of anaplastic foci in diffusely infiltrating gliomas with non-significant contrast-enhancement.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Female; Glioma; H | 2011 |
Proton magnetic resonance spectroscopic imaging in pediatric low-grade gliomas.
Topics: Adolescent; Astrocytoma; Brain; Brain Neoplasms; Child; Child, Preschool; Choline; Creatine; Diagnos | 2010 |
Heterogeneity in malignant gliomas: a magnetic resonance analysis of spatial distribution of metabolite changes and regional blood volume.
Topics: Adult; Aged; Brain Neoplasms; Cerebrovascular Circulation; Choline; Creatine; Female; Glioma; Humans | 2011 |
Metabolic assessment of monofocal acute inflammatory demyelination using MR spectroscopy and (11)C-methionine-, (11)C-choline-, and (18)F-fluorodeoxyglucose-PET.
Topics: Brain Neoplasms; Carbon Radioisotopes; Choline; Creatine; Demyelinating Diseases; Diagnosis, Differe | 2011 |
Predicting the outcome of grade II glioma treated with temozolomide using proton magnetic resonance spectroscopy.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Aspartic Acid; Brain Neoplasms; Choline; Creatine; D | 2011 |
Glioma residual or recurrence versus radiation necrosis: accuracy of pentavalent technetium-99m-dimercaptosuccinic acid [Tc-99m (V) DMSA] brain SPECT compared to proton magnetic resonance spectroscopy (1H-MRS): initial results.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Female; Follow-Up Studie | 2012 |
2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas.
Topics: Algorithms; Aspartic Acid; Brain; Brain Mapping; Brain Neoplasms; Choline; Creatine; Female; Glioma; | 2012 |
2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas.
Topics: Algorithms; Aspartic Acid; Brain; Brain Mapping; Brain Neoplasms; Choline; Creatine; Female; Glioma; | 2012 |
2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas.
Topics: Algorithms; Aspartic Acid; Brain; Brain Mapping; Brain Neoplasms; Choline; Creatine; Female; Glioma; | 2012 |
2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas.
Topics: Algorithms; Aspartic Acid; Brain; Brain Mapping; Brain Neoplasms; Choline; Creatine; Female; Glioma; | 2012 |
Subependymal seeding of low-grade oligodendroglial neoplasms: a case series.
Topics: Adult; Aspartic Acid; Creatine; Disease Progression; Ependyma; Fourth Ventricle; Glioma; Humans; Iso | 2012 |
Single- and multivoxel proton spectroscopy in pediatric patients with diffuse intrinsic pontine glioma.
Topics: Adolescent; Aspartic Acid; Brain Stem Neoplasms; Child; Child, Preschool; Choline; Creatine; Feasibi | 2012 |
Progressive multifocal leukoencephalopathy (PML) mimicking high-grade glioma on delayed F-18 FDG PET imaging.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Diffusion Magnetic Resonance Imaging; Fluorodeoxy | 2012 |
Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas.
Topics: Adolescent; Adult; Aged; Anisotropy; Aspartic Acid; Brain Neoplasms; Cerebral Cortex; Child; Choline | 2012 |
Proton MR spectroscopy of tumefactive demyelinating lesions.
Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Creatine; Demyelinating Diseases; Diagnosis, Different | 2002 |
Correlations between magnetic resonance spectroscopy and image-guided histopathology, with special attention to radiation necrosis.
Topics: Adult; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Glioma; Humans; Lactic Acid; Lip | 2002 |
Combination of single-voxel proton MR spectroscopy and apparent diffusion coefficient calculation in the evaluation of common brain tumors.
Topics: Adolescent; Adult; Aged; Alanine; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creat | 2003 |
[Contribution of magnetic resonance spectrometry to the diagnosis of intracranial tumors].
Topics: Aspartic Acid; Biomarkers; Brain Abscess; Brain Neoplasms; Choline; Computer Graphics; Creatine; Dia | 2002 |
A chemometric approach for brain tumor classification using magnetic resonance imaging and spectroscopy.
Topics: Aspartic Acid; Brain; Brain Chemistry; Brain Neoplasms; Cerebrospinal Fluid; Choline; Creatine; Disc | 2003 |
1H-MRSI of radiation effects in normal-appearing white matter: dose-dependence and impact on automated spectral classification.
Topics: Aspartic Acid; Brain; Brain Chemistry; Brain Neoplasms; Choline; Creatine; Dose-Response Relationshi | 2004 |
[Usefulness of Cho/Cr ratio in proton MR spectroscopy for differentiating residual/recurrent glioma from non-neoplastic lesions].
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Child; Child, Preschool; Choline; Creatine; Female; Glioma | 2004 |
Proton magnetic resonance spectroscopy-guided biopsy for cerebral glial tumors.
Topics: Adult; Aged; Biopsy; Brain Neoplasms; Choline; Creatine; Female; Glioma; Humans; Ki-67 Antigen; Magn | 2004 |
In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard.
Topics: Adult; Aged; Aspartic Acid; Body Water; Brain; Brain Neoplasms; Child; Child, Preschool; Choline; Cr | 2004 |
Perfusion magnetic resonance imaging and magnetic resonance spectroscopy of cerebral gliomas showing imperceptible contrast enhancement on conventional magnetic resonance imaging.
Topics: Adult; Blood Volume; Brain; Choline; Creatine; Female; Glioma; Humans; Magnetic Resonance Angiograph | 2004 |
Proton magnetic resonance spectroscopy of brain tumors correlated with pathology.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creatin | 2005 |
Longitudinal multivoxel MR spectroscopy study of pediatric diffuse brainstem gliomas treated with radiotherapy.
Topics: Aspartic Acid; Brain Stem Neoplasms; Child; Child, Preschool; Choline; Creatine; Disease Progression | 2005 |
The contribution of magnetic resonance spectroscopy and echoplanar perfusion-weighted MRI in the initial assessment of brain tumours.
Topics: Adolescent; Adult; Aged; Astrocytoma; Blood Volume; Brain Neoplasms; Child; Child, Preschool; Cholin | 2005 |
Proton magnetic resonance spectroscopy of normal human brain and glioma: a quantitative in vivo study.
Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Female; Glioma; Glycine; Humans; Inositol; Magnetic | 2005 |
Multisection 1H magnetic resonance spectroscopic imaging assessment of glioma response to chemotherapy.
Topics: Adult; Antineoplastic Agents; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Disease-Free Surviv | 2006 |
Independent component analysis to proton spectroscopic imaging data of human brain tumours.
Topics: Algorithms; Aspartic Acid; Astrocytoma; Brain Neoplasms; Cell Proliferation; Choline; Creatine; Glio | 2005 |
In vitro study of astrocytic tumour metabolism by proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Astrocytes; Astrocytoma; Brain; Brain Neoplasms; Choline; Chromium; Creatine; Gliobla | 2005 |
Preoperative grading of gliomas by using metabolite quantification with high-spatial-resolution proton MR spectroscopic imaging.
Topics: Adolescent; Adult; Aspartic Acid; Brain Neoplasms; Case-Control Studies; Choline; Creatine; Female; | 2006 |
Creatine and antioxidant treatment prevent the inhibition of creatine kinase activity and the morphological alterations of C6 glioma cells induced by the branched-chain alpha-keto acids accumulating in maple syrup urine disease.
Topics: Animals; Antioxidants; Cell Line, Tumor; Cell Shape; Creatine; Creatine Kinase; Glioma; Hemiterpenes | 2006 |
Multiparametric 3T MR approach to the assessment of cerebral gliomas: tumor extent and malignancy.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Contrast Media; Creatine; Diffusio | 2006 |
3T 1H-MR spectroscopy in grading of cerebral gliomas: comparison of short and intermediate echo time sequences.
Topics: Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Echo-Planar Imaging; Female; Glioma; | 2006 |
Disarrangement of fiber tracts and decline of neuronal density correlate in glioma patients--a combined diffusion tensor imaging and 1H-MR spectroscopy study.
Topics: Adult; Aged; Anisotropy; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Cell Size; Choline; Cre | 2006 |
Long-term normal-appearing brain tissue monitoring after irradiation using proton magnetic resonance spectroscopy in vivo: statistical analysis of a large group of patients.
Topics: Adult; Aged; Aspartic Acid; Blood-Brain Barrier; Brain; Brain Neoplasms; Choline; Creatine; Female; | 2006 |
Comments and controversies: magnetic resonance spectroscopy and gliomas.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Humans; Magnetic Resonance Spectroscopy; | 2006 |
Proton magnetic resonance spectroscopy in childhood brainstem lesions.
Topics: Adolescent; Amino Acids; Aspartic Acid; Brain Chemistry; Brain Diseases; Brain Stem; Brain Stem Neop | 2007 |
Use of MR spectroscopy and functional imaging in the treatment planning of gliomas.
Topics: Brain; Brain Neoplasms; Choline; Cranial Irradiation; Creatine; Glioma; Humans; Image Processing, Co | 2007 |
Proton magnetic resonance spectroscopic imaging in the border zone of gliomas: correlation of metabolic and histological changes at low tumor infiltration--initial results.
Topics: Aspartic Acid; Choline; Creatine; Glioma; Humans; Magnetic Resonance Spectroscopy; Neoplasm Invasive | 2007 |
Evaluation of cerebral glioma grade by using normal side creatine as an internal reference in multi-voxel 1H-MR spectroscopy.
Topics: Adult; Aged; Brain Neoplasms; Choline; Creatine; Female; Glioma; Humans; Magnetic Resonance Imaging; | 2007 |
Multimodal MRI in the characterization of glial neoplasms: the combined role of single-voxel MR spectroscopy, diffusion imaging and echo-planar perfusion imaging.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biopsy; Blood Flow Velocity; Brain; Brain Neoplasms; Choline | 2007 |
Dysembryoplastic neuroepithelial tumors: proton MR spectroscopy, diffusion and perfusion characteristics.
Topics: Adolescent; Adult; Blood Flow Velocity; Choline; Creatine; Diagnosis, Differential; Diffusion Magnet | 2007 |
Monovoxel 1H magnetic resonance spectroscopy in the progression of gliomas.
Topics: Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Disease Progression; Female; Glioma; | 2007 |
Analysis of metabolic indices in regions of abnormal perfusion in patients with high-grade glioma.
Topics: Adult; Aged; Brain Neoplasms; Creatine; Female; Glioma; Humans; Lactic Acid; Magnetic Resonance Imag | 2007 |
In vivo proton MR spectroscopy of human gliomas: definition of metabolic coordinates for multi-dimensional classification.
Topics: Adult; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Cluster Analysis; Creatine; Discriminan | 1995 |
Characterization of intracranial mass lesions with in vivo proton MR spectroscopy.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Child; Choline; Crea | 1995 |
Spectral editing with adiabatic pulses.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Carbon Isotopes; Choline; Creatine; Feasibility Studies; Gl | 1995 |
Localised proton spectroscopy and spectroscopic imaging in cerebral gliomas, with comparison to positron emission tomography.
Topics: Aspartic Acid; Brain; Brain Chemistry; Brain Edema; Carbon Radioisotopes; Creatine; Deoxyglucose; Fl | 1995 |
Proton magnetic resonance spectroscopy of astrocytic tumors: an in vitro study.
Topics: Antibodies, Monoclonal; Astrocytoma; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Fe | 1993 |
Non-invasive characterization of brain tumor by in-vivo proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Ependymoma; Glioma; Humans; Magnetic | 1995 |
Proton MR spectroscopy in patients with neurofibromatosis type 1: evaluation of hamartomas and clinical correlation.
Topics: Adolescent; Adult; Aspartic Acid; Astrocytoma; Brain; Brain Diseases; Brain Neoplasms; Cerebellar Di | 1995 |
Effects of therapy on the 1H NMR spectrum of a human glioma line.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Lactates; Magnetic Resonance Spe | 1994 |
Quantitative proton spectroscopy and histology of a canine brain tumor model.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Dogs; Glioma; Lactates; Lactic Acid; Mag | 1993 |
Noninvasive evaluation of malignancy of brain tumors with proton MR spectroscopy.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Energy Metabolism; Femal | 1996 |
Absolute concentrations of metabolites in human brain tumors using in vitro proton magnetic resonance spectroscopy.
Topics: Adenoma; Adolescent; Adult; Aged; Amino Acids; Brain; Brain Neoplasms; Child; Choline; Creatine; Fem | 1997 |
Evaluation of metabolic heterogeneity in brain tumors using 1H-chemical shift imaging method.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Evaluation Studies as Topic; Glioma; Humans; Imag | 1997 |
Increased choline signal coinciding with malignant degeneration of cerebral gliomas: a serial proton magnetic resonance spectroscopy imaging study.
Topics: Adult; Aged; Aspartic Acid; Biomarkers, Tumor; Biopsy; Brain Neoplasms; Cell Transformation, Neoplas | 1997 |
Proton (1H) MR spectroscopy for routine diagnostic evaluation of brain lesions.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Diseases; Brain Neo | 1997 |
MR spectroscopy of bilateral thalamic gliomas.
Topics: Adult; Brain Chemistry; Brain Neoplasms; Creatine; Glioma; Humans; Magnetic Resonance Imaging; Magne | 1999 |
Quantitative proton magnetic resonance spectroscopy of focal brain lesions.
Topics: Adolescent; Aspartic Acid; Biomarkers, Tumor; Brain; Brain Abscess; Brain Diseases; Brain Neoplasms; | 2000 |
Proton magnetic resonance chemical shift imaging (1H CSI)-directed stereotactic biopsy.
Topics: Adult; Aspartic Acid; Biopsy, Needle; Brain; Brain Neoplasms; Creatine; Diagnosis, Differential; Ene | 2001 |
Malignancy of brain tumors evaluated by proton magnetic resonance spectroscopy (1H-MRS) in vitro.
Topics: Biopsy; Brain; Brain Neoplasms; Creatine; Diagnosis, Differential; Energy Metabolism; Glioma; Humans | 2000 |
High glycolytic activity in rat glioma demonstrated in vivo by correlation peak 1H magnetic resonance imaging.
Topics: Alanine; Animals; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Ethanolamines; Female; Glioma; | 2001 |
Mapping extracellular pH in rat brain gliomas in vivo by 1H magnetic resonance spectroscopic imaging: comparison with maps of metabolites.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Buffers; Choline; Contrast Media; Creatine; Extracellular S | 2001 |
Correlation between magnetic resonance spectroscopy imaging and image-guided biopsies: semiquantitative and qualitative histopathological analyses of patients with untreated glioma.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Dominance, Cerebr | 2001 |
Proton magnetic resonance spectroscopy of cerebral glioma after irradiation.
Topics: Brain; Brain Neoplasms; Choline; Creatine; Glioma; Humans; Magnetic Resonance Spectroscopy | 2001 |
High-grade gliomas and solitary metastases: differentiation by using perfusion and proton spectroscopic MR imaging.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Blood Volume; Brain; Brain Chemistry; Bra | 2002 |
Clinical application of proton magnetic resonance spectroscopy in the diagnosis of intracranial mass lesions.
Topics: Aspartic Acid; Brain Abscess; Brain Neoplasms; Cerebral Infarction; Choline; Creatine; Diagnosis, Di | 2002 |
Proton magnetic resonance spectroscopic imaging for metabolic characterization of demyelinating plaques.
Topics: Acute Disease; Adult; Aspartic Acid; Biopsy; Brain Chemistry; Brain Neoplasms; Choline; Creatine; De | 1992 |
Spatially localized in vivo 1H magnetic resonance spectroscopy of an intracerebral rat glioma.
Topics: Animals; Aspartic Acid; Brain; Brain Neoplasms; Creatine; Female; Glioma; Hydrogen; Lactates; Lactic | 1992 |
Detection of metabolic heterogeneity of human intracranial tumors in vivo by 1H NMR spectroscopic imaging.
Topics: Adult; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Creatine; Glioma; Humans; Magnetic Resona | 1990 |