creatine has been researched along with Encephalomyopathies, Mitochondrial in 6 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The mitochondrial encephalomyopathies are chronic progressive disorders affecting predominantly the neuromuscular system." | 1.32 | Effectiveness of creatine monohydrate in mitochondrial encephalomyopathies. ( Hanefeld, FA; Hobbiebrunken, E; Komura, K; Wilichowski, EK, 2003) |
| "Late juvenile neuronal ceroid lipofuscinosis (NCL) is a lysosomal neurodegenerative disorder caused by the accumulation of lipopigment in neurons." | 1.30 | MR imaging and localized proton MR spectroscopy in late infantile neuronal ceroid lipofuscinosis. ( Grodd, W; Klose, U; Nägele, T; Schwab, A; Seeger, U; Seitz, D, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, SK | 1 |
| Kim, J | 1 |
| Kim, HD | 1 |
| Lee, JS | 1 |
| Lee, YM | 1 |
| Komura, K | 1 |
| Hobbiebrunken, E | 1 |
| Wilichowski, EK | 1 |
| Hanefeld, FA | 1 |
| Dager, SR | 1 |
| Friedman, SD | 1 |
| Parow, A | 1 |
| Demopulos, C | 1 |
| Stoll, AL | 1 |
| Lyoo, IK | 1 |
| Dunner, DL | 1 |
| Renshaw, PF | 1 |
| Bowen, J | 1 |
| Richards, T | 1 |
| Maravilla, K | 1 |
| Seitz, D | 1 |
| Grodd, W | 1 |
| Schwab, A | 1 |
| Seeger, U | 1 |
| Klose, U | 1 |
| Nägele, T | 1 |
| Borchert, A | 1 |
| Wilichowski, E | 1 |
| Hanefeld, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Imaging Framework for Testing GABAergic/Glutamatergic Drugs in Bipolar Alcoholics[NCT03220776] | Phase 2 | 54 participants (Actual) | Interventional | 2017-08-07 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Concentrations of GABA+, referenced to unsuppressed water and corrected for within-voxel CSF proportion, in dorsal anterior cingulate cortex measured via Proton Magnetic Resonance Spectroscopy (i.e., MEGA-PRESS). (NCT03220776)
Timeframe: Day 5 of each experimental condition
| Intervention | mmol/kg (Mean) |
|---|---|
| N-Acetylcysteine | 3.90 |
| Gabapentin | 3.93 |
| Placebo Oral Tablet | 3.73 |
Concentrations of Glx (i.e., glutamate + glutamine), referenced to unsuppressed water and corrected for within-voxel CSF proportion, in dorsal anterior cingulate cortex measured via Proton Magnetic Resonance Spectroscopy. (NCT03220776)
Timeframe: Day 5 of each experimental condition
| Intervention | mmol/kg (Mean) |
|---|---|
| N-Acetylcysteine | 21.59 |
| Gabapentin | 21.69 |
| Placebo Oral Tablet | 22.25 |
6 other studies available for creatine and Encephalomyopathies, Mitochondrial
| Article | Year |
|---|---|
Initial experiences with proton MR spectroscopy in treatment monitoring of mitochondrial encephalopathy.
Topics: Adolescent; Child; Child, Preschool; Choline; Creatine; Female; Humans; Infant; Magnetic Resonance S | 2010 |
Effectiveness of creatine monohydrate in mitochondrial encephalomyopathies.
Topics: Adolescent; Adult; Child; Creatine; Exercise Test; Female; Humans; Lactic Acid; Male; MELAS Syndrome | 2003 |
Brain metabolic alterations in medication-free patients with bipolar disorder.
Topics: Adult; Ambulatory Care; Bipolar Disorder; Brain; Brain Chemistry; Creatine; Echo-Planar Imaging; Fem | 2004 |
MR imaging and proton MR spectroscopy in A-to-G substitution at nucleotide position 3243 of leucine transfer RNA.
Topics: Adult; Amino Acid Substitution; Aspartic Acid; Basal Ganglia; Base Sequence; Brain; Cerebral Cortex; | 1998 |
MR imaging and localized proton MR spectroscopy in late infantile neuronal ceroid lipofuscinosis.
Topics: Aspartic Acid; Brain; Brain Diseases; Case-Control Studies; Cerebellum; Cerebral Ventricles; Child; | 1998 |
Supplementation with creatine monohydrate in children with mitochondrial encephalomyopathies.
Topics: Adolescent; Adult; Child; Creatine; Ergometry; Humans; Mitochondrial Encephalomyopathies | 1999 |