creatine has been researched along with Diabetes Mellitus, Type 1 in 32 studies
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate how creatine influences erythrocyte deformability, we determined its effect on erythrocyte filterability in 9 subjects with insulin dependent diabetes (IDDM) without complications, 14 diabetics with uremia and 10 non-diabetic controls." | 3.70 | Effect of creatine on erythrocyte rheology in vitro. ( Gavella, M; Lipovac, V; Mrzljak, V; Rocić, B; Vucić, M, 2000) |
| "Treatments of diabetic nephropathy (DN) delay the onset of end-stage renal disease." | 2.73 | Effects of pyridoxamine in combined phase 2 studies of patients with type 1 and type 2 diabetes and overt nephropathy. ( Bolton, WK; Degenhardt, TP; Khalifah, RG; McGill, JB; Schotzinger, RJ; Williams, ME, 2007) |
| "In 25 children, 6-14 years of age, with type 1 diabetes across 3 sites, we acquired T1WI and axial 2D MRSI along with phantom studies to calibrate scanner effects." | 1.91 | Exploratory Multisite MR Spectroscopic Imaging Shows White Matter Neuroaxonal Loss Associated with Complications of Type 1 Diabetes in Children. ( Alonso, GT; Anderson, AW; Cai, LY; Ghetti, S; Glaser, N; Gwal, K; Jaser, SS; Jones, RS; Jordan, LC; Juvera, J; Kang, H; Landman, BA; Lee, CA; LeStourgeon, LM; Mahon, A; Ozturk, A; Patel, NJ; Pruthi, S; Rewers, A; Rewers, MJ; Taki, I; Tanase, C, 2023) |
| "The role of fetuin-A in type 1 diabetes mellitus (DM) has been less studied." | 1.39 | Lowering effect of valsartan on fetuin-A in type 1 diabetes mellitus. ( Amini, M; Gheissari, A; Javanmard, SH; Khalili, N; Shirzadi, R, 2013) |
| "Insulin-dependent diabetes mellitus (IDDM) is characterized in part by pancreatic β-cell apoptosis." | 1.38 | Acetylcholinesterase is associated with apoptosis in β cells and contributes to insulin-dependent diabetes mellitus pathogenesis. ( Guo, L; Han, Y; Hou, Y; Huang, Q; Lin, B; Lu, L; Ouyang, Q; Wu, J; Yang, L; Yu, L; Zhang, B; Zhang, X, 2012) |
| "Betaine levels were found to be increased in the majority of diabetic mice but decreased in a few animals with severe loss of body weight and physical condition." | 1.35 | Metabolic profile changes in the testes of mice with streptozotocin-induced type 1 diabetes mellitus. ( Agbaje, IM; Amigues, E; Browne, RA; Green, BD; Hollis, J; Mallidis, C; McClure, N; Migaud, M; Rogers, D, 2009) |
| "Eleven IDDM patients with no history of severe hypoglycemia (group A) were compared with 11 IDDM patients who had a history of five or more episodes of severe hypoglycemia (group B)." | 1.30 | Brain abnormalities demonstrated by magnetic resonance imaging in adult IDDM patients with and without a history of recurrent severe hypoglycemia. ( Best, JJ; Deary, IJ; Frier, BM; Perros, P; Sellar, RJ, 1997) |
| "We studied 25 white subjects with IDDM (age = 20." | 1.30 | Nocturnal blood pressure in young patients with insulin-dependent diabetes mellitus: correlation with cardiac function. ( Daniels, SR; Dolan, LM; Eichelberger, SM; Khoury, PR; Kimball, TR; Standiford, DA; Young, LA, 1998) |
| "A total of 201 patients with IDDM for more than 10 years and 159 patients with IDDM for more than 15 years were randomly selected in our hospital." | 1.30 | Genetic polymorphism of renin-angiotensin system is not associated with diabetic vascular complications in Japanese subjects with long-term insulin dependent diabetes mellitus. ( Iwamoto, Y; Miura, J; Omori, Y; Uchigata, Y; Yokoyama, H, 1999) |
| "Sixteen young patients with type 1 diabetes mellitus and rapidly progressive severe retinopathy were examined regarding serum levels of growth hormone before and after the i." | 1.28 | Growth hormone levels in the basal state and after thyrotropin-releasing hormone stimulation in young type 1 (insulin-dependent) diabetic patients with severe retinopathy. ( Agardh, CD; Agardh, E; Eckert, B; Sjöberg, U, 1992) |
| "In regard to diabetic complications, recurrence of diabetic nephropathy was common, but only two patients lost graft function solely for this reason." | 1.28 | Long-term survival following kidney transplantation in 100 type I diabetic patients. ( Fryd, DS; Goetz, FC; Kaufman, DB; Kennedy, WR; Mauer, SM; McHugh, L; Najarian, JS; Navarro, X; Ramsay, RC; Sutherland, DE, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (18.75) | 18.7374 |
| 1990's | 9 (28.13) | 18.2507 |
| 2000's | 8 (25.00) | 29.6817 |
| 2010's | 7 (21.88) | 24.3611 |
| 2020's | 2 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Brugnara, L | 1 |
| García, AI | 1 |
| Murillo, S | 1 |
| Ribalta, J | 1 |
| Fernandez, G | 1 |
| Marquez, S | 1 |
| Rodriguez, MA | 1 |
| Vinaixa, M | 1 |
| Amigó, N | 1 |
| Correig, X | 1 |
| Kalko, S | 1 |
| Pomes, J | 1 |
| Novials, A | 1 |
| Cai, LY | 1 |
| Tanase, C | 1 |
| Anderson, AW | 1 |
| Patel, NJ | 1 |
| Lee, CA | 1 |
| Jones, RS | 1 |
| LeStourgeon, LM | 1 |
| Mahon, A | 1 |
| Taki, I | 1 |
| Juvera, J | 1 |
| Pruthi, S | 1 |
| Gwal, K | 1 |
| Ozturk, A | 1 |
| Kang, H | 1 |
| Rewers, A | 1 |
| Rewers, MJ | 1 |
| Alonso, GT | 1 |
| Glaser, N | 1 |
| Ghetti, S | 1 |
| Jaser, SS | 1 |
| Landman, BA | 1 |
| Jordan, LC | 1 |
| Gheissari, A | 1 |
| Javanmard, SH | 1 |
| Shirzadi, R | 1 |
| Amini, M | 1 |
| Khalili, N | 1 |
| Zhao, C | 1 |
| Luo, Q | 1 |
| He, F | 1 |
| Peng, F | 1 |
| Xia, X | 1 |
| Huang, F | 1 |
| Yu, X | 1 |
| Williams, GM | 1 |
| Long, AE | 1 |
| Wilson, IV | 1 |
| Aitken, RJ | 1 |
| Wyatt, RC | 1 |
| McDonald, TJ | 1 |
| Wong, FS | 1 |
| Hattersley, AT | 1 |
| Williams, AJ | 1 |
| Bingley, PJ | 1 |
| Gillespie, KM | 1 |
| Wootton-Gorges, SL | 1 |
| Buonocore, MH | 1 |
| Caltagirone, RA | 1 |
| Kuppermann, N | 1 |
| Glaser, NS | 1 |
| Wetter, J | 1 |
| Gohlke, BC | 1 |
| Woelfle, JF | 1 |
| Zhang, B | 2 |
| Yang, L | 1 |
| Yu, L | 1 |
| Lin, B | 1 |
| Hou, Y | 1 |
| Wu, J | 1 |
| Huang, Q | 1 |
| Han, Y | 1 |
| Guo, L | 1 |
| Ouyang, Q | 1 |
| Lu, L | 1 |
| Zhang, X | 1 |
| Cherney, DZ | 1 |
| Scholey, JW | 1 |
| Daneman, D | 1 |
| Dunger, DB | 1 |
| Dalton, RN | 1 |
| Moineddin, R | 1 |
| Mahmud, FH | 1 |
| Dekker, R | 1 |
| Elia, Y | 1 |
| Sochett, E | 1 |
| Reich, HN | 1 |
| MIELER, W | 1 |
| Obrosova, IG | 1 |
| Mabley, JG | 1 |
| Zsengellér, Z | 1 |
| Charniauskaya, T | 1 |
| Abatan, OI | 1 |
| Groves, JT | 1 |
| Szabó, C | 1 |
| Bischof, MG | 1 |
| Brehm, A | 1 |
| Bernroider, E | 1 |
| Krssák, M | 1 |
| Mlynárik, V | 1 |
| Krebs, M | 1 |
| Roden, M | 1 |
| Jeansson, M | 1 |
| Granqvist, AB | 1 |
| Nyström, JS | 1 |
| Haraldsson, B | 1 |
| Williams, ME | 1 |
| Bolton, WK | 1 |
| Khalifah, RG | 1 |
| Degenhardt, TP | 1 |
| Schotzinger, RJ | 1 |
| McGill, JB | 1 |
| Mallidis, C | 1 |
| Green, BD | 1 |
| Rogers, D | 1 |
| Agbaje, IM | 1 |
| Hollis, J | 1 |
| Migaud, M | 1 |
| Amigues, E | 1 |
| McClure, N | 1 |
| Browne, RA | 1 |
| Selam, JL | 1 |
| Giraud, P | 1 |
| Mirouze, J | 1 |
| Perros, P | 1 |
| Deary, IJ | 1 |
| Sellar, RJ | 1 |
| Best, JJ | 1 |
| Frier, BM | 1 |
| Bowen, J | 1 |
| Richards, T | 1 |
| Maravilla, K | 1 |
| Young, LA | 1 |
| Kimball, TR | 1 |
| Daniels, SR | 1 |
| Standiford, DA | 1 |
| Khoury, PR | 1 |
| Eichelberger, SM | 1 |
| Dolan, LM | 1 |
| Hägg, E | 1 |
| Carlberg, BC | 1 |
| Hillörn, VS | 1 |
| Villumsen, J | 1 |
| Miura, J | 1 |
| Uchigata, Y | 1 |
| Yokoyama, H | 1 |
| Omori, Y | 1 |
| Iwamoto, Y | 1 |
| Lipovac, V | 1 |
| Gavella, M | 1 |
| Vucić, M | 1 |
| Mrzljak, V | 1 |
| Rocić, B | 1 |
| Mattock, MB | 1 |
| Cronin, N | 1 |
| Cavallo-Perin, P | 1 |
| Idzior-Walus, B | 1 |
| Penno, G | 1 |
| Bandinelli, S | 1 |
| Standl, E | 2 |
| Kofinis, A | 1 |
| Fuller, JH | 1 |
| Zywiec, J | 1 |
| Grzeszczak, W | 1 |
| Pierzchała, K | 1 |
| Agardh, CD | 1 |
| Agardh, E | 1 |
| Eckert, B | 1 |
| Sjöberg, U | 1 |
| Lane, PH | 1 |
| Steffes, MW | 1 |
| Mauer, SM | 2 |
| Martin, S | 1 |
| Schernthaner, G | 1 |
| Nerup, J | 1 |
| Gries, FA | 1 |
| Koivisto, VA | 1 |
| Dupré, J | 2 |
| Hamet, P | 1 |
| McArthur, R | 1 |
| Tan, MH | 1 |
| Atkison, PR | 1 |
| Mahon, JL | 1 |
| Stiller, CR | 1 |
| Jenner, MR | 1 |
| Paul, TL | 1 |
| Momah, CI | 1 |
| Najarian, JS | 1 |
| Kaufman, DB | 1 |
| Fryd, DS | 1 |
| McHugh, L | 1 |
| Ramsay, RC | 1 |
| Kennedy, WR | 1 |
| Navarro, X | 1 |
| Goetz, FC | 1 |
| Sutherland, DE | 1 |
| Dullaart, RP | 1 |
| Roelse, H | 1 |
| Sluiter, WJ | 1 |
| Doorenbos, H | 1 |
| Spesivtseva, VG | 1 |
| Mamaeva, GG | 1 |
| Starosel'tseva, LK | 1 |
| Kozlova, EG | 1 |
| Verger, MF | 1 |
| Larpent, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomised, Double Blind, Placebo Controlled Trial of Angiotensin Converting Enzyme Inhibitors and Statins in the Prevention of Long Term Complications in Young People With Type 1 Diabetes[NCT01581476] | Phase 3 | 443 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
| [NCT00005180] | 0 participants | Observational | 1985-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for creatine and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Urinary markers of renal inflammation in adolescents with Type 1 diabetes mellitus and normoalbuminuria.
Topics: Adolescent; Albuminuria; Biomarkers; Chemokines; Child; Creatine; Cytokines; Diabetes Mellitus, Type | 2012 |
Effects of pyridoxamine in combined phase 2 studies of patients with type 1 and type 2 diabetes and overt nephropathy.
Topics: Adolescent; Adult; Aged; Creatine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Ne | 2007 |
Magnesium therapy in type 1 diabetes. A double blind study concerning the effects on kidney function and serum lipid levels.
Topics: Adult; Albuminuria; Creatine; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Fibrinogen; He | 1999 |
Follow-up of cyclosporin A treatment in type 1 (insulin-dependent) diabetes mellitus: lack of long-term effects.
Topics: Adolescent; Adult; Blood Pressure; Child; Creatine; Cyclosporins; Diabetes Mellitus, Type 1; Double- | 1991 |
Interaction of bromocriptine and cyclosporine in insulin dependent diabetes mellitus: results from the Canadian open study.
Topics: Blood Glucose; Bromocriptine; C-Peptide; Creatine; Cyclosporins; Diabetes Mellitus, Type 1; Drug Syn | 1990 |
27 other studies available for creatine and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Muscular carnosine is a marker for cardiorespiratory fitness and cardiometabolic risk factors in men with type 1 diabetes.
Topics: Biomarkers; Cardiometabolic Risk Factors; Cardiorespiratory Fitness; Carnosine; Creatine; Diabetes M | 2022 |
Exploratory Multisite MR Spectroscopic Imaging Shows White Matter Neuroaxonal Loss Associated with Complications of Type 1 Diabetes in Children.
Topics: Aspartic Acid; Brain; Child; Choline; Creatine; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Gl | 2023 |
Lowering effect of valsartan on fetuin-A in type 1 diabetes mellitus.
Topics: Adult; Albuminuria; alpha-2-HS-Glycoprotein; Angiotensin II Type 1 Receptor Blockers; Cholesterol, L | 2013 |
Establishing HbA1c -mean blood glucose formulae for patients on continuous ambulatory peritoneal dialysis.
Topics: Adult; Blood Glucose; Creatine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephr | 2014 |
Beta cell function and ongoing autoimmunity in long-standing, childhood onset type 1 diabetes.
Topics: Adolescent; Adult; Autoantibodies; Autoimmunity; C-Peptide; Child; Creatine; Diabetes Mellitus, Type | 2016 |
Progressive decrease in N-acetylaspartate/Creatine ratio in a teenager with type 1 diabetes and repeated episodes of ketoacidosis without clinically apparent cerebral edema: Evidence for permanent brain injury.
Topics: Adolescent; Aspartic Acid; Basal Ganglia; Blood Glucose; Brain; Brain Damage, Chronic; Brain Edema; | 2010 |
Hyperglycemic hyperosmolar state as initial manifestation of pediatric insulin-dependent diabetes.
Topics: Autoantibodies; Blood Glucose; Child, Preschool; Combined Modality Therapy; Creatine; Diabetes Melli | 2012 |
Acetylcholinesterase is associated with apoptosis in β cells and contributes to insulin-dependent diabetes mellitus pathogenesis.
Topics: Acetylcholinesterase; Animals; Apoptosis; Blood Glucose; Creatine; Diabetes Mellitus, Experimental; | 2012 |
[CREATINE CONTENT IN THE SERUM OF NORMAL AND SICK CHILDREN].
Topics: Adolescent; Blood Chemical Analysis; Blood Donors; Child; Communicable Diseases; Creatine; Creatinin | 1964 |
Role for nitrosative stress in diabetic neuropathy: evidence from studies with a peroxynitrite decomposition catalyst.
Topics: Animals; Blood Glucose; Creatine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabet | 2005 |
Cerebral glutamate metabolism during hypoglycaemia in healthy and type 1 diabetic humans.
Topics: Adult; Blood Glucose; Creatine; Diabetes Mellitus, Type 1; Energy Metabolism; Epinephrine; Glucagon; | 2006 |
Functional and molecular alterations of the glomerular barrier in long-term diabetes in mice.
Topics: Albumins; Animals; Blood Pressure; Blotting, Western; Body Weight; Creatine; Decorin; Diabetes Melli | 2006 |
Metabolic profile changes in the testes of mice with streptozotocin-induced type 1 diabetes mellitus.
Topics: Animals; Betaine; Carnitine; Choline; Creatine; Diabetes Mellitus, Experimental; Diabetes Mellitus, | 2009 |
The point of no-return for the diabetic kidney is beyond clinical proteinuria.
Topics: Adult; Creatine; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Glomerular Filtration Rate; Huma | 1984 |
Brain abnormalities demonstrated by magnetic resonance imaging in adult IDDM patients with and without a history of recurrent severe hypoglycemia.
Topics: Adult; Aspartic Acid; Atrophy; Blood Glucose; Brain; Cerebral Cortex; Choline; Cognition; Cohort Stu | 1997 |
MR imaging and proton MR spectroscopy in A-to-G substitution at nucleotide position 3243 of leucine transfer RNA.
Topics: Adult; Amino Acid Substitution; Aspartic Acid; Basal Ganglia; Base Sequence; Brain; Cerebral Cortex; | 1998 |
Nocturnal blood pressure in young patients with insulin-dependent diabetes mellitus: correlation with cardiac function.
Topics: Adolescent; Adult; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Creatine | 1998 |
Genetic polymorphism of renin-angiotensin system is not associated with diabetic vascular complications in Japanese subjects with long-term insulin dependent diabetes mellitus.
Topics: Adult; Albuminuria; Angiotensinogen; Blood Pressure; Cohort Studies; Creatine; Diabetes Mellitus, Ty | 1999 |
Effect of creatine on erythrocyte rheology in vitro.
Topics: Adolescent; Adult; Aged; Creatine; Diabetes Mellitus, Type 1; Erythrocyte Deformability; Erythrocyte | 2000 |
Plasma lipids and urinary albumin excretion rate in Type 1 diabetes mellitus: the EURODIAB IDDM Complications Study.
Topics: Adult; Age of Onset; Albuminuria; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Cholestero | 2001 |
[Bone complication in diabetes subjects with good metabolic control and without longterm complications: certain problems. Part II. Basal parameters of bone turnover].
Topics: Alkaline Phosphatase; Bone Resorption; Creatine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type | 2001 |
Growth hormone levels in the basal state and after thyrotropin-releasing hormone stimulation in young type 1 (insulin-dependent) diabetic patients with severe retinopathy.
Topics: Adult; Albuminuria; Blood Pressure; Creatine; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Femal | 1992 |
Glomerular structure in IDDM women with low glomerular filtration rate and normal urinary albumin excretion.
Topics: Adult; Albuminuria; Biopsy; Blood Pressure; Creatine; Diabetes Mellitus, Type 1; Female; Glomerular | 1992 |
Long-term survival following kidney transplantation in 100 type I diabetic patients.
Topics: Age Factors; Cadaver; Creatine; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Neuropat | 1989 |
Variability of albumin excretion in diabetes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albuminuria; Creatine; Data Collection; Diabetes Mellitu | 1989 |
[Early detection of nephroangiopathy in patients with diabetes mellitus and approaches to its correction].
Topics: Creatine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Neph | 1989 |
[Hypertensive type I diabetics have a higher level of microalbuminuria than normotensives irrespective of blood glucose equilibrium].
Topics: Adolescent; Adult; Aged; Albuminuria; Blood Glucose; Creatine; Diabetes Mellitus, Type 1; Diabetic A | 1988 |