Page last updated: 2024-10-17

creatine and Demyelinating Diseases

creatine has been researched along with Demyelinating Diseases in 28 studies

Demyelinating Diseases: Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.

Research Excerpts

ExcerptRelevanceReference
" Severe hyponatremia and hypoosmolality induced profound decreases in levels of brain electrolytes, amino acids (especially taurine), and creatine."7.67Adaptive decreases in amino acids (taurine in particular), creatine, and electrolytes prevent cerebral edema in chronically hyponatremic mice: rapid correction (experimental model of central pontine myelinolysis) causes dehydration and shrinkage of brain. ( Hauhart, RE; Nelson, JS; Thurston, JH, 1987)
"Citrulline was more frequently identified in the brains of patients with early-onset MS than in healthy subjects by (1)H-MR spectroscopy, suggesting an association of increased citrullination of myelin proteins with demyelinating diseases."5.14Assessment of citrullinated myelin by 1H-MR spectroscopy in early-onset multiple sclerosis. ( Aksu, AO; Anlar, B; Haspolat, S; Karabulut, E; Kurne, A; Kurul, S; Oguz, KK; Senbil, N; Serdaroglu, A; Teber, S, 2009)
"Cerebral creatine deficiency syndrome (CCDS) is an inborn error of metabolism characterized by intellectual delays, seizures, and autistic-like behavior."4.31Cerebral Creatine Deficiency Affects the Timing of Oligodendrocyte Myelination. ( Albanese, C; Gentile, T; Hu, J; Huang, JK; Lee, Y; Manavi, Z; Melchor, GS; Rodriguez, O; Rosko, LM; Shults, NV; Smith, VN, 2023)
"Eight patients with advanced breast cancer were entered into a prospective, longitudinal trial that included examination by MR imaging and proton MR spectroscopy before chemotherapy and through 12 months after treatment with carmustine, cyclophosphamide, and cisplatin, combined with autologous hematopoietic progenitor cell support (AHPCS)."3.70White matter disease induced by high-dose chemotherapy: longitudinal study with MR imaging and proton spectroscopy. ( Brown, MS; Cagnoni, PJ; Jones, RB; Sheeder, JL; Simon, JH; Stears, JC; Stemmer, SM, 1998)
" Severe hyponatremia and hypoosmolality induced profound decreases in levels of brain electrolytes, amino acids (especially taurine), and creatine."3.67Adaptive decreases in amino acids (taurine in particular), creatine, and electrolytes prevent cerebral edema in chronically hyponatremic mice: rapid correction (experimental model of central pontine myelinolysis) causes dehydration and shrinkage of brain. ( Hauhart, RE; Nelson, JS; Thurston, JH, 1987)
"Monofocal acute inflammatory demyelination (MAID), which is observable by CT and MRI as a well-enhanced mass lesion with prominent perifocal edema, is very similar to malignant gliomas radiologically, making differential diagnosis of the two pathologies difficult."1.37Metabolic assessment of monofocal acute inflammatory demyelination using MR spectroscopy and (11)C-methionine-, (11)C-choline-, and (18)F-fluorodeoxyglucose-PET. ( Aki, T; Asano, Y; Ito, T; Iwama, T; Miwa, K; Shinoda, J; Takenaka, S; Yokoyama, K, 2011)
"MR studies of these infants showed obstructive hydrocephalus caused by mass effect produced by an enlarged cerebellum."1.30Imaging studies in a unique familial dysmyelinating disorder. ( Duhaime, AC; Gripp, KW; Molloy, PT; Muenke, M; Rorke, LB; Schut, L; Tucker, SH; Wang, ZJ; Zackai, EH; Zimmerman, RA, 1998)
"Four grades of demyelination and three grades of cerebral atrophy were distinguished by magnetic resonance imaging criteria."1.281H and 31P magnetic resonance spectroscopy of the brain in degenerative cerebral disorders. ( den Hollander, JA; Luyten, PR; Nauta, JJ; Valk, J; van der Grond, J; van der Knaap, MS, 1992)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.14)18.7374
1990's9 (32.14)18.2507
2000's10 (35.71)29.6817
2010's6 (21.43)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Rosko, LM1
Gentile, T1
Smith, VN1
Manavi, Z1
Melchor, GS1
Hu, J1
Shults, NV1
Albanese, C1
Lee, Y1
Rodriguez, O1
Huang, JK1
Praet, J1
Orije, J1
Kara, F1
Guglielmetti, C1
Santermans, E1
Daans, J1
Hens, N1
Verhoye, M1
Berneman, Z1
Ponsaerts, P1
Van der Linden, A1
Takanashi, J1
Oguz, KK1
Kurne, A1
Aksu, AO1
Karabulut, E1
Serdaroglu, A1
Teber, S1
Haspolat, S1
Senbil, N1
Kurul, S1
Anlar, B1
Machado, A1
Soares-Fernandes, J1
Ribeiro, M1
Rodrigues, M1
Cerqueira, J1
Ferreira, C1
Sohn, SY1
Ko, YJ1
Hong, JM1
Kim, SH1
Kim, HS1
Kim, JH1
Chi, JG1
Moon, SY1
Kato, Z1
Morimoto, M1
Orii, KE1
Kato, T1
Kondo, N1
Beppu, T1
Nishimoto, H1
Fujiwara, S1
Kudo, K1
Sanjo, K1
Narumi, S1
Oikawa, H1
Onodera, M1
Ogasawara, K1
Sasaki, M1
Takenaka, S1
Shinoda, J1
Asano, Y1
Aki, T1
Miwa, K1
Ito, T1
Yokoyama, K1
Iwama, T1
Saindane, AM1
Cha, S1
Law, M1
Xue, X1
Knopp, EA1
Zagzag, D1
Gambini, A1
Falini, A1
Moiola, L1
Comi, G1
Scotti, G1
Ohtake, H1
Shimohata, T1
Terajima, K1
Kimura, T1
Jo, R1
Kaseda, R1
Iizuka, O1
Takano, M1
Akaiwa, Y1
Goto, H1
Kobayashi, H1
Sugai, T1
Muratake, T1
Hosoki, T1
Shioiri, T1
Okamoto, K1
Onodera, O1
Tanaka, K1
Someya, T1
Nakada, T1
Tsuji, S1
Porto, L1
Hattingen, E1
Pilatus, U1
Kieslich, M1
Yan, B1
Schwabe, D1
Zanella, FE1
Lanfermann, H1
Cianfoni, A1
Niku, S1
Imbesi, SG1
Hiehle, JF1
Lenkinski, RE2
Grossman, RI2
Dousset, V1
Ramer, KN1
Schnall, MD1
Cohen, JA1
Gonzalez-Scarano, F2
Hájek, M1
Hejcmanová, L1
Prádný, J1
Confort-Gouny, S1
Vion-Dury, J1
Chabrol, B1
Nicoli, F1
Cozzone, PJ1
Kimura, H1
Brown, MS1
Stemmer, SM1
Simon, JH1
Stears, JC1
Jones, RB1
Cagnoni, PJ1
Sheeder, JL1
Gripp, KW1
Zimmerman, RA1
Wang, ZJ1
Rorke, LB1
Duhaime, AC1
Schut, L1
Molloy, PT1
Tucker, SH1
Zackai, EH1
Muenke, M1
van der Knaap, MS2
Wevers, RA1
Struys, EA1
Verhoeven, NM1
Pouwels, PJ1
Engelke, UF1
Feikema, W1
Valk, J2
Jakobs, C1
Blüml, S1
Hwang, JH1
Moreno, A1
Ross, BD1
Pozdniakov, AV1
Tiutin, LA1
Bisaga, GN1
Odinak, MM1
Espay, AJ1
Bodensteiner, JB1
Patel, H1
van der Grond, J1
Luyten, PR1
den Hollander, JA1
Nauta, JJ1
Arnold, DL1
Matthews, PM1
Francis, GS1
O'Connor, J1
Antel, JP1
Thurston, JH1
Hauhart, RE1
Nelson, JS1
Takei, Y1

Reviews

1 review available for creatine and Demyelinating Diseases

ArticleYear
Neurochemistry of Hypomyelination Investigated with MR Spectroscopy.
    Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2015, Volume: 14, Issue:2

    Topics: Animals; Aspartic Acid; Brain Chemistry; Choline; Creatine; Demyelinating Diseases; Disease Models,

2015

Trials

1 trial available for creatine and Demyelinating Diseases

ArticleYear
Assessment of citrullinated myelin by 1H-MR spectroscopy in early-onset multiple sclerosis.
    AJNR. American journal of neuroradiology, 2009, Volume: 30, Issue:4

    Topics: Adolescent; Age of Onset; Aspartic Acid; Child; Child, Preschool; Choline; Citrulline; Creatine; Dem

2009

Other Studies

26 other studies available for creatine and Demyelinating Diseases

ArticleYear
Cerebral Creatine Deficiency Affects the Timing of Oligodendrocyte Myelination.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023, 02-15, Volume: 43, Issue:7

    Topics: Animals; Creatine; Demyelinating Diseases; Female; Homozygote; Intellectual Disability; Male; Mice;

2023
Cuprizone-induced demyelination and demyelination-associated inflammation result in different proton magnetic resonance metabolite spectra.
    NMR in biomedicine, 2015, Volume: 28, Issue:4

    Topics: Animals; Aspartic Acid; Brain Chemistry; Choline; Creatine; Cuprizone; Demyelinating Diseases; Dipep

2015
Alcohol abuse and acute behavioural disturbances in a 24-year-old patient. Diagnosis: Marchiafava-Bignami disease (MBD).
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2009, Volume: 16, Issue:6

    Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Aspartic Acid; Choline; Corpus Callosum; Crea

2009
A case of pigmentary orthochromatic leukodystrophy with findings of proton MR spectroscopy and serial brain MRIs.
    Journal of the neurological sciences, 2010, Aug-15, Volume: 295, Issue:1-2

    Topics: Adult; Antigens, CD; Aspartic Acid; Brain; Brain Diseases; Brain Mapping; Creatine; Demyelinating Di

2010
Developmental changes of radiological findings in Fukuyama-type congenital muscular dystrophy.
    Pediatric radiology, 2010, Volume: 40 Suppl 1

    Topics: Biomarkers; Choline; Creatine; Demyelinating Diseases; Humans; Infant; Magnetic Resonance Imaging; M

2010
1H-magnetic resonance spectroscopy indicates damage to cerebral white matter in the subacute phase after CO poisoning.
    Journal of neurology, neurosurgery, and psychiatry, 2011, Volume: 82, Issue:8

    Topics: Brain; Brain Diseases, Metabolic; Carbon Monoxide Poisoning; Choline; Creatine; Demyelinating Diseas

2011
Metabolic assessment of monofocal acute inflammatory demyelination using MR spectroscopy and (11)C-methionine-, (11)C-choline-, and (18)F-fluorodeoxyglucose-PET.
    Brain tumor pathology, 2011, Volume: 28, Issue:3

    Topics: Brain Neoplasms; Carbon Radioisotopes; Choline; Creatine; Demyelinating Diseases; Diagnosis, Differe

2011
Proton MR spectroscopy of tumefactive demyelinating lesions.
    AJNR. American journal of neuroradiology, 2002, Volume: 23, Issue:8

    Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Creatine; Demyelinating Diseases; Diagnosis, Different

2002
Marchiafava-Bignami disease: longitudinal MR imaging and MR spectroscopy study.
    AJNR. American journal of neuroradiology, 2003, Volume: 24, Issue:2

    Topics: Alcohol-Related Disorders; Atrophy; Choline; Corpus Callosum; Creatine; Demyelinating Diseases; Huma

2003
Adult-onset leukoencephalopathy with vanishing white matter with a missense mutation in EIF2B5.
    Neurology, 2004, May-11, Volume: 62, Issue:9

    Topics: Adult; Age of Onset; Brain; Creatine; Demyelinating Diseases; DNA Mutational Analysis; Eukaryotic In

2004
Proton magnetic resonance spectroscopy in childhood brainstem lesions.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2007, Volume: 23, Issue:3

    Topics: Adolescent; Amino Acids; Aspartic Acid; Brain Chemistry; Brain Diseases; Brain Stem; Brain Stem Neop

2007
Metabolite findings in tumefactive demyelinating lesions utilizing short echo time proton magnetic resonance spectroscopy.
    AJNR. American journal of neuroradiology, 2007, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Demyelinating Diseases;

2007
Correlation of spectroscopy and magnetization transfer imaging in the evaluation of demyelinating lesions and normal appearing white matter in multiple sclerosis.
    Magnetic resonance in medicine, 1994, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Choline; Cohort Studies; Creatine; Demyelinating Dise

1994
Proton in vivo spectroscopy of patients with hyperphenylalaninaemia.
    Neuropediatrics, 1993, Volume: 24, Issue:2

    Topics: Adult; Aspartic Acid; Biopterins; Brain; Brain Chemistry; Brain Diseases; Child; Choline; Creatine;

1993
Localised proton magnetic resonance spectroscopy in X-linked adrenoleukodystrophy.
    Neuroradiology, 1995, Volume: 37, Issue:7

    Topics: Adolescent; Adrenoleukodystrophy; Adult; Aspartic Acid; Brain; Child; Creatine; Demyelinating Diseas

1995
Proton MR spectroscopy and magnetization transfer ratio in multiple sclerosis: correlative findings of active versus irreversible plaque disease.
    AJNR. American journal of neuroradiology, 1996, Volume: 17, Issue:8

    Topics: Adult; Aspartic Acid; Brain; Brain Diseases; Brain Edema; Choline; Chronic Disease; Creatine; Demyel

1996
White matter disease induced by high-dose chemotherapy: longitudinal study with MR imaging and proton spectroscopy.
    AJNR. American journal of neuroradiology, 1998, Volume: 19, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Brain; Brain Diseases; B

1998
Imaging studies in a unique familial dysmyelinating disorder.
    AJNR. American journal of neuroradiology, 1998, Volume: 19, Issue:7

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Canavan Disease; Cerebellar Diseases; Cerebral Cortex; Chol

1998
Leukoencephalopathy associated with a disturbance in the metabolism of polyols.
    Annals of neurology, 1999, Volume: 46, Issue:6

    Topics: Adolescent; Aspartic Acid; Carbohydrate Metabolism, Inborn Errors; Choline; Creatine; Demyelinating

1999
Novel peak assignments of in vivo (13)C MRS in human brain at 1.5 T.
    Journal of magnetic resonance (San Diego, Calif. : 1997), 2000, Volume: 143, Issue:2

    Topics: Adult; Aspartic Acid; Bicarbonates; Brain; Carbon Isotopes; Child, Preschool; Creatine; Demyelinatin

2000
[Proton magnetic-resonance spectroscopy in remitting and secondary-progressive multiple sclerosis].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2001, Volume: 101, Issue:4

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Choline; Creatine; Demyelinating Diseases; Female; gamma-Am

2001
Episodic coma in a new leukodystrophy.
    Pediatric neurology, 2002, Volume: 26, Issue:2

    Topics: Aspartic Acid; Ataxia; Brain; Child; Choline; Coma; Creatine; Demyelinating Diseases; Epilepsy, Post

2002
1H and 31P magnetic resonance spectroscopy of the brain in degenerative cerebral disorders.
    Annals of neurology, 1992, Volume: 31, Issue:2

    Topics: Adult; Aspartic Acid; Atrophy; Brain; Brain Diseases; Child; Creatine; Demyelinating Diseases; Human

1992
Proton magnetic resonance spectroscopic imaging for metabolic characterization of demyelinating plaques.
    Annals of neurology, 1992, Volume: 31, Issue:3

    Topics: Acute Disease; Adult; Aspartic Acid; Biopsy; Brain Chemistry; Brain Neoplasms; Choline; Creatine; De

1992
Adaptive decreases in amino acids (taurine in particular), creatine, and electrolytes prevent cerebral edema in chronically hyponatremic mice: rapid correction (experimental model of central pontine myelinolysis) causes dehydration and shrinkage of brain.
    Metabolic brain disease, 1987, Volume: 2, Issue:4

    Topics: Acclimatization; Adenine Nucleotides; Amino Acids; Animals; Brain; Brain Edema; Creatine; Demyelinat

1987
Infantile neuroaxonal dystrophy. (Seitelberger's disease). Report of an autopsy case.
    Acta neuropathologica, 1965, Oct-04, Volume: 5, Issue:1

    Topics: Basal Ganglia; Central Nervous System Diseases; Cerebellar Cortex; Child, Preschool; Consanguinity;

1965