Page last updated: 2024-10-17

creatine and Dementia, Vascular

creatine has been researched along with Dementia, Vascular in 13 studies

Dementia, Vascular: An imprecise term referring to dementia associated with CEREBROVASCULAR DISORDERS, including CEREBRAL INFARCTION (single or multiple), and conditions associated with chronic BRAIN ISCHEMIA. Diffuse, cortical, and subcortical subtypes have been described. (From Gerontol Geriatr 1998 Feb;31(1):36-44)

Research Excerpts

ExcerptRelevanceReference
"The 2 patients with vascular dementia showed clinical improvement with marked increases in the NAA/Cre ratio and mini-mental score."2.69Effect of thrombin inhibition in vascular dementia and silent cerebrovascular disease. An MR spectroscopy study. ( Hoshide, S; Kario, K; Matsuo, T; Shimada, K; Umeda, Y, 1999)
"Choline (Cho)/Cr was higher than normal in patients with AD, FTLD, and DLB."1.321H MR spectroscopy in common dementias. ( Boeve, BF; Edland, SD; Ferman, TJ; Ivnik, RJ; Jack, CR; Kantarci, K; Knopman, DS; O'Brien, PC; Petersen, RC; Smith, GE; Tang-Wai, DF; Tangalos, EG; Weigand, SD, 2004)
"Subcortical ischemic vascular dementia is associated with cortical hypometabolism and hypoperfusion, and this reduced cortical metabolism or blood flow can be detected with functional imaging such as positron emission tomography."1.31Subcortical ischemic vascular dementia: assessment with quantitative MR imaging and 1H MR spectroscopy. ( Amend, DL; Capizzano, AA; Chui, HC; Fein, G; Jagust, W; Maudsley, AA; Norman, D; Schuff, N; Segal, MR; Tanabe, JL; Weiner, MW, 2000)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (30.77)18.2507
2000's6 (46.15)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Regenold, WT1
Blumenthal, JB1
Loreck, DJ1
Mordecai, KL1
Scarinzi, G1
Doddi, SR1
Adler, L1
Gasparovic, C1
Prestopnik, J1
Thompson, J1
Taheri, S1
Huisa, B1
Schrader, R1
Adair, JC1
Rosenberg, GA2
Watanabe, T1
Shiino, A1
Akiguchi, I1
Algin, O1
Hakyemez, B1
Parlak, M1
Weiss, U1
Bacher, R1
Vonbank, H1
Kemmler, G1
Lingg, A1
Marksteiner, J1
Kantarci, K1
Petersen, RC1
Boeve, BF1
Knopman, DS1
Tang-Wai, DF1
O'Brien, PC1
Weigand, SD1
Edland, SD1
Smith, GE1
Ivnik, RJ1
Ferman, TJ1
Tangalos, EG1
Jack, CR1
Constans, JM2
Meyerhoff, DJ2
Gerson, J1
MacKay, S2
Norman, D3
Fein, G3
Weiner, MW3
Kattapong, VJ1
Brooks, WM1
Wesley, MH1
Kodituwakku, PW1
Kario, K1
Matsuo, T1
Hoshide, S1
Umeda, Y1
Shimada, K1
George, AE1
Cha, S1
Capizzano, AA1
Schuff, N1
Amend, DL1
Tanabe, JL1
Maudsley, AA1
Jagust, W1
Chui, HC1
Segal, MR1
De Stefano, N1
Balestri, P1
Dotti, MT1
Grosso, S1
Mortilla, M1
Morgese, G1
Federico, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II, Randomized, Crossover, Single Blind, Safety Trial of DABIGATRAN Versus ASA for Preventing Ischaemic Brain Lesions in Patients Affected by CADASIL[NCT01361763]Phase 250 participants (Anticipated)Interventional2011-06-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for creatine and Dementia, Vascular

ArticleYear
Absolute quantification in proton magnetic resonance spectroscopy is superior to relative ratio to discriminate Alzheimer's disease from Binswanger's disease.
    Dementia and geriatric cognitive disorders, 2008, Volume: 26, Issue:1

    Topics: Aged; Alzheimer Disease; Aspartic Acid; Choline; Creatine; Dementia, Vascular; Diagnosis, Differenti

2008
Effect of thrombin inhibition in vascular dementia and silent cerebrovascular disease. An MR spectroscopy study.
    Stroke, 1999, Volume: 30, Issue:5

    Topics: Aged; Antithrombin III; Antithrombins; Arginine; Aspartic Acid; Biomarkers; Blood Coagulation; Brain

1999

Other Studies

11 other studies available for creatine and Dementia, Vascular

ArticleYear
Elevated Plasma Aβ42 in Cognitively Impaired Individuals Taking ACE Inhibitor Antihypertensives.
    American journal of Alzheimer's disease and other dementias, 2017, Volume: 32, Issue:6

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amnesia; Amyloid beta-Peptides; Angiotensin-Converting E

2017
1H-MR spectroscopy metabolite levels correlate with executive function in vascular cognitive impairment.
    Journal of neurology, neurosurgery, and psychiatry, 2013, Volume: 84, Issue:7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Biomarkers; Brain Ischemia; Choline; Cogn

2013
Proton MR spectroscopy and white matter hyperintensities in idiopathic normal pressure hydrocephalus and other dementias.
    The British journal of radiology, 2010, Volume: 83, Issue:993

    Topics: Adult; Aged; Aspartic Acid; Choline; Creatine; Dementia, Vascular; Diagnosis, Differential; Female;

2010
Cognitive impairment: assessment with brain magnetic resonance imaging and proton magnetic resonance spectroscopy.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:3

    Topics: Aged; Alzheimer Disease; Aspartic Acid; Brain; Brain Chemistry; Choline; Cognition Disorders; Creati

2003
1H MR spectroscopy in common dementias.
    Neurology, 2004, Oct-26, Volume: 63, Issue:8

    Topics: Acetylcholine; Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Brain; Brain Chemistry; Ch

2004
H-1 MR spectroscopic imaging of white matter signal hyperintensities: Alzheimer disease and ischemic vascular dementia.
    Radiology, 1995, Volume: 197, Issue:2

    Topics: Aged; Alzheimer Disease; Aspartic Acid; Brain; Brain Diseases; Brain Ischemia; Case-Control Studies;

1995
Regional gray and white matter metabolite differences in subjects with AD, with subcortical ischemic vascular dementia, and elderly controls with 1H magnetic resonance spectroscopic imaging.
    Archives of neurology, 1996, Volume: 53, Issue:2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Aspartic Acid; Brain; Brain Ischem

1996
Proton magnetic resonance spectroscopy of vascular- and Alzheimer-type dementia.
    Archives of neurology, 1996, Volume: 53, Issue:7

    Topics: Aged; Alzheimer Disease; Aspartic Acid; Brain; Choline; Creatine; Dementia, Vascular; Diagnosis, Dif

1996
Applying functional MR imaging to brain-behavioral research: can we do better than simple clinical measures?
    AJNR. American journal of neuroradiology, 2000, Volume: 21, Issue:4

    Topics: Aspartic Acid; Brain; Brain Ischemia; Creatine; Dementia, Vascular; Humans; Magnetic Resonance Imagi

2000
Subcortical ischemic vascular dementia: assessment with quantitative MR imaging and 1H MR spectroscopy.
    AJNR. American journal of neuroradiology, 2000, Volume: 21, Issue:4

    Topics: Aged; Aspartic Acid; Brain Ischemia; Creatine; Dementia, Vascular; Female; Humans; Magnetic Resonanc

2000
Severe metabolic abnormalities in the white matter of patients with vacuolating megalencephalic leukoencephalopathy with subcortical cysts. A proton MR spectroscopic imaging study.
    Journal of neurology, 2001, Volume: 248, Issue:5

    Topics: Adolescent; Adult; Aspartic Acid; Creatine; Cysts; Dementia, Vascular; Disease Progression; Female;

2001