creatine has been researched along with Cognitive Dysfunction in 43 studies
Cognitive Dysfunction: Diminished or impaired mental and/or intellectual function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mutations in the creatine (Cr) transporter (CrT) gene lead to cerebral creatine deficiency syndrome-1 (CCDS1), an X-linked metabolic disorder characterized by cerebral Cr deficiency causing intellectual disability, seizures, movement and autistic-like behavioural disturbances, language and speech impairment." | 7.83 | A mouse model for creatine transporter deficiency reveals early onset cognitive impairment and neuropathology associated with brain aging. ( Alessandrì, MG; Baroncelli, L; Cacciante, F; Cioni, G; Leuzzi, V; Molinaro, A; Napoli, D; Pizzorusso, T; Putignano, E; Tola, J, 2016) |
| "The effects of creatine on brain metabolism and the potential cognitive enhancing properties of this compound raise the possibility of developing a new augmentation therapeutic strategy in schizophrenia especially in patients demonstrating negative and cognitive symptomatology." | 7.81 | A pilot open study of long term high dose creatine augmentation in patients with treatment resistant negative symptoms schizophrenia. ( Bersudsky, Y; Dwalatzky, T; Lerner, V; Levental, U; Levine, J; Medina, S, 2015) |
| "The NAA/Cr (N-acetyl aspartate/creatine) of the bilateral hippocampus of the cognitive impairment group was lower than those of both control group of stroke and health (p < 0." | 3.85 | Study on the clinical application of the MRS in the cognitive assessment after stroke. ( Chen, W; Gong, ZK; Sheng, C; Wang, M; Wang, SY; Wang, XX, 2017) |
| "Mutations in the creatine (Cr) transporter (CrT) gene lead to cerebral creatine deficiency syndrome-1 (CCDS1), an X-linked metabolic disorder characterized by cerebral Cr deficiency causing intellectual disability, seizures, movement and autistic-like behavioural disturbances, language and speech impairment." | 3.83 | A mouse model for creatine transporter deficiency reveals early onset cognitive impairment and neuropathology associated with brain aging. ( Alessandrì, MG; Baroncelli, L; Cacciante, F; Cioni, G; Leuzzi, V; Molinaro, A; Napoli, D; Pizzorusso, T; Putignano, E; Tola, J, 2016) |
| "The effects of creatine on brain metabolism and the potential cognitive enhancing properties of this compound raise the possibility of developing a new augmentation therapeutic strategy in schizophrenia especially in patients demonstrating negative and cognitive symptomatology." | 3.81 | A pilot open study of long term high dose creatine augmentation in patients with treatment resistant negative symptoms schizophrenia. ( Bersudsky, Y; Dwalatzky, T; Lerner, V; Levental, U; Levine, J; Medina, S, 2015) |
| "Eighteen (N=18) patients with bipolar depression according to DSM-IV criteria who were enrollled in a 6-week, randomized, double-blind, placebo-controlled trial of creatine monohydrate 6g daily as adjunctive therapy were submitted to neuropsychological assessments (Wisconsin Card Sorting Test, Digit Span subtest of the Wechsler Adult Intelligence Scale-Third Edition, Stroop Color-Word Test, Rey-Osterrieth complex figure test, FAS Verbal Fluency Test) at baseline and week 6." | 2.84 | Cognitive effects of creatine monohydrate adjunctive therapy in patients with bipolar depression: Results from a randomized, double-blind, placebo-controlled trial. ( Dias, RDS; Fernandes, FBF; Lafer, B; Silva, M; Toniolo, RA, 2017) |
| "In total, 40 ESRD patients and 30 healthy controls were prospectively enrolled in our study." | 1.72 | Abnormal cerebral micro-structures in end-stage renal disease patients related to mild cognitive impairment. ( Dai, J; Jiao, Z; Liu, T; Shi, H; Zheng, J, 2022) |
| "Diagnosis of Parkinson's disease (PD) cognitive impairment at early stages is challenging compared to the stage of PD dementia where functional impairment is apparent and easily diagnosed." | 1.62 | Frontal lobe metabolic alterations characterizing Parkinson's disease cognitive impairment. ( Chaudhary, S; Goyal, V; Jagannathan, NR; Kalaivani, M; Kaloiya, GS; Kumaran, SS; Mehta, N; Sagar, R; Srivastava, AK, 2021) |
| "Creatine (Cr) is a guanidino compound that provides readily available phosphate pools for the regeneration of spent adenosine triphosphate (ATP)." | 1.51 | Deletion of the creatine transporter gene in neonatal, but not adult, mice leads to cognitive deficits. ( Abdulla, ZI; Delcimmuto, N; Kokenge, AN; Perna, MK; Skelton, MR; Udobi, KC, 2019) |
| "Markers of nocturnal hypoxemia and SDB are associated with cerebral oxidative stress in older people at-risk for dementia, suggesting a potential mechanism by which SDB may contribute to brain degeneration, cognitive decline, and dementia." | 1.43 | Association of Anterior Cingulate Glutathione with Sleep Apnea in Older Adults At-Risk for Dementia. ( Cross, N; Duffy, SL; Grunstein, R; Hermens, DF; Hickie, IB; Lagopoulos, J; Lewis, SJ; Mowszowski, L; Naismith, SL; Terpening, Z, 2016) |
| "Amnestic mild cognitive impairment (aMCI) is often the prodromal stage to AD." | 1.43 | (1)H-MRS asymmetry changes in the anterior and posterior cingulate gyrus in patients with mild cognitive impairment and mild Alzheimer's disease. ( Chen, W; Chen, X; Guo, Z; Hou, H; Liu, X; Shen, Y; Wei, F, 2016) |
| "Increasing evidence suggest that Alzheimer's disease (AD) is a heterogeneous disorder that includes several subtypes with different etiology and progression." | 1.40 | Decreased cerebrospinal fluid levels of L-carnitine in non-apolipoprotein E4 carriers at early stages of Alzheimer's disease. ( Cedazo-Mínguez, Á; Cifuentes, A; Ibáñez, C; Lodeiro, M; Simó, C, 2014) |
| "The diagnosis of mild or questionable Alzheimer's disease (AD) depends on clinical criteria that often leave a margin for doubt." | 1.37 | Contribution of 1H spectroscopy to a brief cognitive-functional test battery for the diagnosis of mild Alzheimer's disease. ( Andreiuolo, PA; Bottino, CM; de Oliveira-Souza, R; Moll, J; Silveira de Souza, A; Tovar-Moll, F, 2011) |
| "Amnestic mild cognitive impairment (MCI) is highly predictive of Alzheimer's disease but the pace of deterioration varies across patients." | 1.37 | Longitudinal magnetic resonance spectroscopy as marker of cognitive deterioration in mild cognitive impairment. ( Fayed, N; Modrego, PJ, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 32 (74.42) | 24.3611 |
| 2020's | 11 (25.58) | 2.80 |
| Authors | Studies |
|---|---|
| Shad, KF | 1 |
| Soubra, W | 1 |
| Cordato, DJ | 1 |
| Cengiz, S | 1 |
| Arslan, DB | 1 |
| Kicik, A | 1 |
| Erdogdu, E | 1 |
| Yildirim, M | 1 |
| Hatay, GH | 1 |
| Tufekcioglu, Z | 1 |
| Uluğ, AM | 1 |
| Bilgic, B | 1 |
| Hanagasi, H | 1 |
| Demiralp, T | 1 |
| Gurvit, H | 1 |
| Ozturk-Isik, E | 1 |
| Gozdas, E | 1 |
| Hinkley, L | 1 |
| Fingerhut, H | 1 |
| Dacorro, L | 1 |
| Gu, M | 1 |
| Sacchet, MD | 1 |
| Hurd, R | 1 |
| Hosseini, SMH | 1 |
| Huang, X | 1 |
| Lai, S | 1 |
| Lu, X | 1 |
| Wang, Y | 1 |
| Zhang, Y | 2 |
| Chen, G | 1 |
| Chen, P | 1 |
| Ye, K | 1 |
| Duan, M | 1 |
| Song, K | 1 |
| Zhong, S | 1 |
| Jia, Y | 1 |
| Zheng, J | 3 |
| Jiao, Z | 3 |
| Dai, J | 3 |
| Liu, T | 3 |
| Shi, H | 3 |
| Levin, O | 1 |
| Vints, WAJ | 1 |
| Ziv, G | 1 |
| Katkutė, G | 1 |
| Kušleikienė, S | 1 |
| Valatkevičienė, K | 1 |
| Sheoran, S | 1 |
| Drozdova-Statkevičienė, M | 1 |
| Gleiznienė, R | 1 |
| Pääsuke, M | 1 |
| Dudonienė, V | 1 |
| Himmelreich, U | 1 |
| Česnaitienė, VJ | 1 |
| Masiulis, N | 1 |
| Lyros, E | 1 |
| Ragoschke-Schumm, A | 1 |
| Kostopoulos, P | 1 |
| Sehr, A | 1 |
| Backens, M | 1 |
| Kalampokini, S | 1 |
| Decker, Y | 1 |
| Lesmeister, M | 1 |
| Liu, Y | 2 |
| Reith, W | 1 |
| Fassbender, K | 1 |
| Chaudhary, S | 1 |
| Kumaran, SS | 1 |
| Goyal, V | 1 |
| Kalaivani, M | 1 |
| Kaloiya, GS | 1 |
| Sagar, R | 1 |
| Mehta, N | 1 |
| Srivastava, AK | 1 |
| Jagannathan, NR | 1 |
| Peña-Bautista, C | 1 |
| Torres-Cuevas, I | 1 |
| Baquero, M | 1 |
| Ferrer, I | 1 |
| García, L | 1 |
| Vento, M | 1 |
| Cháfer-Pericás, C | 1 |
| Alirezaei, Z | 1 |
| Amouheidari, A | 1 |
| Hassanpour, M | 1 |
| Davanian, F | 1 |
| Iraji, S | 1 |
| Shokrani, P | 1 |
| Nazem-Zadeh, MR | 1 |
| Mao, X | 1 |
| Kelty, TJ | 1 |
| Kerr, NR | 1 |
| Childs, TE | 1 |
| Roberts, MD | 1 |
| Booth, FW | 1 |
| Regenold, WT | 1 |
| Blumenthal, JB | 1 |
| Loreck, DJ | 1 |
| Mordecai, KL | 1 |
| Scarinzi, G | 1 |
| Doddi, SR | 1 |
| Adler, L | 1 |
| Wang, SY | 1 |
| Wang, M | 1 |
| Wang, XX | 1 |
| Chen, W | 2 |
| Sheng, C | 1 |
| Gong, ZK | 1 |
| Shih, CM | 1 |
| Lai, JJ | 1 |
| Chang, CC | 1 |
| Chen, CS | 1 |
| Yeh, YC | 1 |
| Jaw, TS | 1 |
| Hsu, JS | 1 |
| Li, CW | 1 |
| Udobi, KC | 2 |
| Kokenge, AN | 2 |
| Hautman, ER | 1 |
| Ullio, G | 1 |
| Coene, J | 1 |
| Williams, MT | 1 |
| Vorhees, CV | 1 |
| Mabondzo, A | 1 |
| Skelton, MR | 2 |
| Sklirou, E | 1 |
| Lichter-Konecki, U | 1 |
| Kroll, JL | 1 |
| Steele, AM | 1 |
| Pinkham, AE | 1 |
| Choi, C | 1 |
| Khan, DA | 1 |
| Patel, SV | 1 |
| Chen, JR | 1 |
| Aslan, S | 1 |
| Sherwood Brown, E | 1 |
| Ritz, T | 1 |
| Alakkas, A | 1 |
| Ellis, RJ | 1 |
| Watson, CW | 1 |
| Umlauf, A | 1 |
| Heaton, RK | 1 |
| Letendre, S | 1 |
| Collier, A | 1 |
| Marra, C | 1 |
| Clifford, DB | 1 |
| Gelman, B | 1 |
| Sacktor, N | 1 |
| Morgello, S | 1 |
| Simpson, D | 1 |
| McCutchan, JA | 1 |
| Kallianpur, A | 1 |
| Gianella, S | 1 |
| Marcotte, T | 1 |
| Grant, I | 1 |
| Fennema-Notestine, C | 1 |
| Molinaro, A | 2 |
| Alessandrì, MG | 2 |
| Putignano, E | 2 |
| Leuzzi, V | 2 |
| Cioni, G | 2 |
| Baroncelli, L | 2 |
| Pizzorusso, T | 2 |
| Delcimmuto, N | 1 |
| Abdulla, ZI | 1 |
| Perna, MK | 1 |
| Cassol, G | 1 |
| Godinho, DB | 1 |
| de Zorzi, VN | 1 |
| Farinha, JB | 1 |
| Della-Pace, ID | 1 |
| de Carvalho Gonçalves, M | 1 |
| Oliveira, MS | 1 |
| Furian, AF | 1 |
| Fighera, MR | 1 |
| Royes, LFF | 1 |
| Cai, ZL | 1 |
| Xue, S | 1 |
| Zhou, X | 1 |
| Wu, F | 1 |
| Kantarci, K | 1 |
| Tumati, S | 1 |
| Martens, S | 1 |
| Aleman, A | 1 |
| Targosz-Gajniak, MG | 1 |
| Siuda, JS | 1 |
| Wicher, MM | 1 |
| Banasik, TJ | 1 |
| Bujak, MA | 1 |
| Augusciak-Duma, AM | 1 |
| Opala, G | 1 |
| Lodeiro, M | 1 |
| Ibáñez, C | 1 |
| Cifuentes, A | 1 |
| Simó, C | 1 |
| Cedazo-Mínguez, Á | 1 |
| Suriyajakryuththana, W | 1 |
| Tuntiyatorn, L | 1 |
| Teepprasarn, N | 1 |
| Sukying, C | 1 |
| Li, Z | 1 |
| Wang, P | 1 |
| Yu, Z | 1 |
| Cong, Y | 1 |
| Sun, H | 1 |
| Zhang, J | 2 |
| Sun, C | 1 |
| Ju, X | 1 |
| Levental, U | 1 |
| Bersudsky, Y | 1 |
| Dwalatzky, T | 1 |
| Lerner, V | 1 |
| Medina, S | 1 |
| Levine, J | 1 |
| Almuqbel, M | 1 |
| Melzer, TR | 1 |
| Myall, DJ | 1 |
| MacAskill, MR | 1 |
| Pitcher, TL | 1 |
| Livingston, L | 1 |
| Wood, KL | 1 |
| Keenan, RJ | 1 |
| Dalrymple-Alford, JC | 1 |
| Anderson, TJ | 1 |
| Duffy, SL | 1 |
| Lagopoulos, J | 1 |
| Terpening, Z | 1 |
| Lewis, SJ | 1 |
| Grunstein, R | 1 |
| Mowszowski, L | 1 |
| Cross, N | 1 |
| Hermens, DF | 1 |
| Hickie, IB | 1 |
| Naismith, SL | 1 |
| Meng, N | 1 |
| Shi, S | 1 |
| Su, Y | 1 |
| Auriel, E | 1 |
| Kliper, E | 1 |
| Shenhar-Tsarfaty, S | 1 |
| Molad, J | 1 |
| Berliner, S | 1 |
| Shapira, I | 1 |
| Ben-Bashat, D | 1 |
| Shopin, L | 1 |
| Tene, O | 1 |
| Rosenberg, GA | 1 |
| Bornstein, NM | 1 |
| Ben Assayag, E | 1 |
| Guo, Z | 1 |
| Liu, X | 1 |
| Hou, H | 1 |
| Wei, F | 1 |
| Chen, X | 1 |
| Shen, Y | 1 |
| Cacciante, F | 1 |
| Napoli, D | 1 |
| Tola, J | 1 |
| Koob, M | 1 |
| Viola, A | 1 |
| Le Fur, Y | 1 |
| Viout, P | 1 |
| Ratiney, H | 1 |
| Confort-Gouny, S | 1 |
| Cozzone, PJ | 1 |
| Girard, N | 1 |
| Toniolo, RA | 1 |
| Fernandes, FBF | 1 |
| Silva, M | 1 |
| Dias, RDS | 1 |
| Lafer, B | 1 |
| Foy, CM | 1 |
| Daly, EM | 1 |
| Glover, A | 1 |
| O'Gorman, R | 1 |
| Simmons, A | 1 |
| Murphy, DG | 1 |
| Lovestone, S | 1 |
| Wang, T | 1 |
| Xiao, S | 1 |
| Li, X | 1 |
| Ding, B | 1 |
| Ling, H | 1 |
| Chen, K | 1 |
| Fang, Y | 1 |
| Fayed, N | 2 |
| Modrego, PJ | 2 |
| Rojas-Salinas, G | 1 |
| Aguilar, K | 1 |
| Silveira de Souza, A | 1 |
| de Oliveira-Souza, R | 1 |
| Moll, J | 1 |
| Tovar-Moll, F | 1 |
| Andreiuolo, PA | 1 |
| Bottino, CM | 1 |
| Lim, TS | 1 |
| Hong, YH | 1 |
| Choi, JY | 1 |
| Kim, HS | 1 |
| Moon, SY | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Open Label Study for the Use of Tyrosine Kinase Inhibitors for Treatment of Cognitive Decline Due to Degenerative Dementias[NCT02921477] | Phase 1 | 150 participants (Anticipated) | Interventional | 2016-09-30 | Enrolling by invitation | ||
| Focused Ultrasound Delivery of Exosomes for Treatment of Refractory Depression, Anxiety, and Neurodegenerative Dementias[NCT04202770] | 300 participants (Anticipated) | Interventional | 2019-12-01 | Suspended (stopped due to Pending COVID-19 pandemic; pending status of product development) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for creatine and Cognitive Dysfunction
| Article | Year |
|---|---|
Inborn Errors of Metabolism with Cognitive Impairment: Metabolism Defects of Phenylalanine, Homocysteine and Methionine, Purine and Pyrimidine, and Creatine.
Topics: Cognitive Dysfunction; Creatine; Diagnosis, Differential; Homocysteine; Humans; Metabolism, Inborn E | 2018 |
Potential therapeutic implications of ergogenic compounds on pathophysiology induced by traumatic brain injury: A narrative review.
Topics: Animals; Arginine; Brain Injuries, Traumatic; Caffeine; Carnitine; Central Nervous System Stimulants | 2019 |
Proton MRS in mild cognitive impairment.
Topics: Alzheimer Disease; Animals; Aspartic Acid; Biomarkers; Brain; Choline; Cognitive Dysfunction; Creati | 2013 |
Magnetic resonance spectroscopy in mild cognitive impairment: systematic review and meta-analysis.
Topics: Aspartic Acid; Choline; Cognitive Dysfunction; Creatine; Humans; Inositol; Magnetic Resonance Spectr | 2013 |
2 trials available for creatine and Cognitive Dysfunction
| Article | Year |
|---|---|
The effect of creatine and coenzyme q10 combination therapy on mild cognitive impairment in Parkinson's disease.
Topics: Aged; Cognition; Cognitive Dysfunction; Creatine; Drug Therapy, Combination; Female; Humans; Male; M | 2015 |
Cognitive effects of creatine monohydrate adjunctive therapy in patients with bipolar depression: Results from a randomized, double-blind, placebo-controlled trial.
Topics: Adult; Antidepressive Agents; Bipolar Disorder; Cognition; Cognitive Dysfunction; Combined Modality | 2017 |
37 other studies available for creatine and Cognitive Dysfunction
| Article | Year |
|---|---|
The Auditory Afferent Pathway as a Clinical Marker of Alzheimer's Disease.
Topics: Acoustic Stimulation; Afferent Pathways; Aged; Alzheimer Disease; Aspartic Acid; Biomarkers; Cerebra | 2022 |
Identification of metabolic correlates of mild cognitive impairment in Parkinson's disease using magnetic resonance spectroscopic imaging and machine learning.
Topics: Cognitive Dysfunction; Creatine; Humans; Inositol; Machine Learning; Magnetic Resonance Imaging; Mag | 2022 |
Topics: Aged; Alzheimer Disease; Aspartic Acid; Cognition; Cognitive Dysfunction; Creatine; Glutamic Acid; H | 2022 |
Cognitive dysfunction and neurometabolic alternations in major depressive disorder with gastrointestinal symptoms.
Topics: Aspartic Acid; Choline; Cognitive Dysfunction; Creatine; Depressive Disorder, Major; Humans; Proton | 2023 |
Abnormal cerebral micro-structures in end-stage renal disease patients related to mild cognitive impairment.
Topics: Brain; Cognitive Dysfunction; Creatine; Diffusion Tensor Imaging; Humans; Kidney Failure, Chronic | 2022 |
Abnormal cerebral micro-structures in end-stage renal disease patients related to mild cognitive impairment.
Topics: Brain; Cognitive Dysfunction; Creatine; Diffusion Tensor Imaging; Humans; Kidney Failure, Chronic | 2022 |
Abnormal cerebral micro-structures in end-stage renal disease patients related to mild cognitive impairment.
Topics: Brain; Cognitive Dysfunction; Creatine; Diffusion Tensor Imaging; Humans; Kidney Failure, Chronic | 2022 |
Abnormal cerebral micro-structures in end-stage renal disease patients related to mild cognitive impairment.
Topics: Brain; Cognitive Dysfunction; Creatine; Diffusion Tensor Imaging; Humans; Kidney Failure, Chronic | 2022 |
Abnormal cerebral micro-structures in end-stage renal disease patients related to mild cognitive impairment.
Topics: Brain; Cognitive Dysfunction; Creatine; Diffusion Tensor Imaging; Humans; Kidney Failure, Chronic | 2022 |
Abnormal cerebral micro-structures in end-stage renal disease patients related to mild cognitive impairment.
Topics: Brain; Cognitive Dysfunction; Creatine; Diffusion Tensor Imaging; Humans; Kidney Failure, Chronic | 2022 |
Abnormal cerebral micro-structures in end-stage renal disease patients related to mild cognitive impairment.
Topics: Brain; Cognitive Dysfunction; Creatine; Diffusion Tensor Imaging; Humans; Kidney Failure, Chronic | 2022 |
Abnormal cerebral micro-structures in end-stage renal disease patients related to mild cognitive impairment.
Topics: Brain; Cognitive Dysfunction; Creatine; Diffusion Tensor Imaging; Humans; Kidney Failure, Chronic | 2022 |
Abnormal cerebral micro-structures in end-stage renal disease patients related to mild cognitive impairment.
Topics: Brain; Cognitive Dysfunction; Creatine; Diffusion Tensor Imaging; Humans; Kidney Failure, Chronic | 2022 |
Neurometabolic correlates of posturography in normal aging and older adults with mild cognitive impairment: Evidence from a
Topics: Aged; Aging; Aspartic Acid; Choline; Cognitive Dysfunction; Creatine; Glutamine; Humans; Inositol; P | 2023 |
Normal brain aging and Alzheimer's disease are associated with lower cerebral pH: an in vivo histidine
Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Brain; Cognitive Dysfunction; Creatine; De | 2020 |
Frontal lobe metabolic alterations characterizing Parkinson's disease cognitive impairment.
Topics: Aspartic Acid; Brain; Cognitive Dysfunction; Creatine; Frontal Lobe; Gray Matter; Humans; Magnetic R | 2021 |
Early neurotransmission impairment in non-invasive Alzheimer Disease detection.
Topics: Acetylcholine; Aged; Alzheimer Disease; Amino Acids; Biomarkers; Cognitive Dysfunction; Creatine; Fe | 2020 |
Early Detection of Radiation-Induced Injury and Prediction of Cognitive Deficit by MRS Metabolites in Radiotherapy of Low-Grade Glioma.
Topics: Adolescent; Adult; Aspartic Acid; Brain Neoplasms; Cognitive Dysfunction; Creatine; Early Diagnosis; | 2021 |
Creatine Supplementation Upregulates mTORC1 Signaling and Markers of Synaptic Plasticity in the Dentate Gyrus While Ameliorating LPS-Induced Cognitive Impairment in Female Rats.
Topics: Animal Nutritional Physiological Phenomena; Animals; Behavior, Animal; Cognitive Dysfunction; Creati | 2021 |
Elevated Plasma Aβ42 in Cognitively Impaired Individuals Taking ACE Inhibitor Antihypertensives.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amnesia; Amyloid beta-Peptides; Angiotensin-Converting E | 2017 |
Study on the clinical application of the MRS in the cognitive assessment after stroke.
Topics: Aspartic Acid; Cognition; Cognition Disorders; Cognitive Dysfunction; Creatine; Hippocampus; Humans; | 2017 |
Comparison of LCModel and SAGE in Analysis of Brain Metabolite Concentrations-A study of Patients with Mild Cognitive Impairment.
Topics: Aspartic Acid; Brain; Case-Control Studies; Choline; Cognitive Dysfunction; Creatine; Humans; Magnet | 2017 |
Cognitive deficits and increases in creatine precursors in a brain-specific knockout of the creatine transporter gene Slc6a8.
Topics: Animals; Brain; Brain Diseases, Metabolic, Inborn; Cognitive Dysfunction; Creatine; Fear; Learning; | 2018 |
Hippocampal metabolites in asthma and their implications for cognitive function.
Topics: Adolescent; Adult; Aspartic Acid; Asthma; Cognition; Cognitive Dysfunction; Creatine; Female; Glutam | 2018 |
White matter damage, neuroinflammation, and neuronal integrity in HAND.
Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Aspartic Acid; | 2019 |
A Nervous System-Specific Model of Creatine Transporter Deficiency Recapitulates the Cognitive Endophenotype of the Disease: a Longitudinal Study.
Topics: Animals; Brain Diseases, Metabolic, Inborn; Cognitive Dysfunction; Creatine; Disease Models, Animal; | 2019 |
Deletion of the creatine transporter gene in neonatal, but not adult, mice leads to cognitive deficits.
Topics: Animals; Brain; Brain Diseases, Metabolic, Inborn; Cognitive Dysfunction; Creatine; Fear; Female; Ma | 2019 |
Proxies of cognitive reserve and their effects on neuropsychological performance in patients with mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Biomarkers; Choline; Cognitive Dysfunction; Cognitive Reserv | 2013 |
Magnetic resonance spectroscopy as a predictor of conversion of mild cognitive impairment to dementia.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Choline; Cognitive Dysfunction; Creatine; Dementia; D | 2013 |
Magnetic resonance spectroscopy as a predictor of conversion of mild cognitive impairment to dementia.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Choline; Cognitive Dysfunction; Creatine; Dementia; D | 2013 |
Magnetic resonance spectroscopy as a predictor of conversion of mild cognitive impairment to dementia.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Choline; Cognitive Dysfunction; Creatine; Dementia; D | 2013 |
Magnetic resonance spectroscopy as a predictor of conversion of mild cognitive impairment to dementia.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Choline; Cognitive Dysfunction; Creatine; Dementia; D | 2013 |
Decreased cerebrospinal fluid levels of L-carnitine in non-apolipoprotein E4 carriers at early stages of Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Apolipoprotein E4; Arginine; Biomarkers; Carnitine; | 2014 |
Proton magnetic resonance spectroscopy in mild cognitive impairment and Alzheimer's disease: a preliminary study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Case-Control Studies; Choline; Cognitive | 2014 |
A pilot open study of long term high dose creatine augmentation in patients with treatment resistant negative symptoms schizophrenia.
Topics: Adult; Antipsychotic Agents; Cognitive Dysfunction; Creatine; Drug Resistance; Drug Synergism; Femal | 2015 |
Metabolite ratios in the posterior cingulate cortex do not track cognitive decline in Parkinson's disease in a clinical setting.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Bayes Theorem; Case-Control Studies; Choline; Cognitive Dysf | 2016 |
Association of Anterior Cingulate Glutathione with Sleep Apnea in Older Adults At-Risk for Dementia.
Topics: Aged; Aging; Biomarkers; Cognition Disorders; Cognitive Dysfunction; Creatine; Dementia; Depression; | 2016 |
Proton magnetic resonance spectroscopy as a diagnostic biomarker in mild cognitive impairment following stroke in acute phase.
Topics: Aged; Aspartic Acid; Biomarkers; Cognitive Dysfunction; Creatine; Female; Hippocampus; Humans; Male; | 2016 |
Impaired renal function is associated with brain atrophy and poststroke cognitive decline.
Topics: Aged; Atrophy; Brain; Brain Ischemia; Cognitive Dysfunction; Creatine; Diffusion Tensor Imaging; Fem | 2016 |
(1)H-MRS asymmetry changes in the anterior and posterior cingulate gyrus in patients with mild cognitive impairment and mild Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Aspartic Acid; Choline; Cognitive Dysfunction; Creatine; Dominance, Cerebra | 2016 |
A mouse model for creatine transporter deficiency reveals early onset cognitive impairment and neuropathology associated with brain aging.
Topics: Aging; Animals; Brain; Brain Diseases, Metabolic, Inborn; Cognitive Dysfunction; Creatine; Disease M | 2016 |
Creatine, Glutamine plus Glutamate, and Macromolecules Are Decreased in the Central White Matter of Premature Neonates around Term.
Topics: Cognitive Dysfunction; Creatine; Diffusion Magnetic Resonance Imaging; Female; Glutamic Acid; Glutam | 2016 |
Hippocampal proton MR spectroscopy in early Alzheimer's disease and mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Case-Control Studies; Choline; Cognitive | 2011 |
Using proton magnetic resonance spectroscopy to identify mild cognitive impairment.
Topics: Aged; Alzheimer Disease; Aspartic Acid; Brain; Case-Control Studies; Choline; Cognitive Dysfunction; | 2012 |
Brain glutamate levels are decreased in Alzheimer's disease: a magnetic resonance spectroscopy study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Choline; Cognitive Dysfunction; Creatine; | 2011 |
Contribution of 1H spectroscopy to a brief cognitive-functional test battery for the diagnosis of mild Alzheimer's disease.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Cognitive Dys | 2011 |
Longitudinal magnetic resonance spectroscopy as marker of cognitive deterioration in mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Brain; Cognitive Dysfunction; Creatine; F | 2011 |
Functional investigation of bilateral posterior cingulate gyri using multivoxel MR spectroscopy.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Cognitive Dys | 2012 |