creatine has been researched along with Chemical and Drug Induced Liver Injury in 21 studies
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Isotretinoin is the most effective acne therapy available, but has the potential for a number of adverse side effects, including transaminitis." | 3.85 | Dietary Supplements, Isotretinoin, and Liver Toxicity in Adolescents: A Retrospective Case Series. ( DeKlotz, CMC; Friedlander, SF; Roby, KD, 2017) |
| " Both rat strains treated with 10g/kg DEG had equivalent degrees of metabolic acidosis, renal toxicity (increased BUN and creatinine and cortical necrosis) and liver toxicity (increased serum enzyme levels, centrilobular necrosis and severe glycogen depletion)." | 3.81 | Diethylene glycol-induced toxicities show marked threshold dose response in rats. ( Abreo, F; Dunning, CL; Landry, GM; Latimer, B; McMartin, KE; Orchard, E, 2015) |
| "Tacrolimus (FK506) is an immunosuppressive agent and has toxic side effects such as nephrotoxicity, hepatotoxicity, and neurotoxicity." | 1.72 | Protective effect of silymarin on tacrolimus-induced kidney and liver toxicity. ( Ciftci, MK; Terzi, F, 2022) |
| "We investigated and reported toxic hepatitis in 20 male athletes following self-prescribing of a number of dietary supplements which are lesser known." | 1.38 | Toxic hepatitis in a group of 20 male body-builders taking dietary supplements. ( Aryan, E; Balali-Mood, M; Riahi-Zanjani, B; Sadeghi, M; Timcheh-Hariri, A, 2012) |
| "Acetaminophen (APAP) is a commonly used and effective analgesic and antipyretic agent." | 1.38 | Enhancement of acetaminophen-induced chronic hepatotoxicity in restricted fed rats: a nonclinical approach to acetaminophen-induced chronic hepatotoxicity in susceptible patients. ( Hashimoto, T; Kobayashi, A; Kondo, K; Kuno, H; Shoda, T; Sugai, S; Suzuki, Y; Takahashi, A; Toyoda, K; Yamada, N, 2012) |
| " Since S-adenosylmethionine (SAMe) is the primary source of the sulfur atom in glutathione, UPLC/MS and NMR were used to evaluate metabolites involved with the transulfuration pathway in urine samples collected during studies of eight liver toxic compounds in Sprague-Dawley rats." | 1.35 | Evaluations of the trans-sulfuration pathway in multiple liver toxicity studies. ( Beger, RD; Chen, M; Dragan, Y; Holland, RD; Schnackenberg, LK; Sun, J; Tong, W; Welsh, W, 2009) |
| " Experimental groups were dosed with target doses of 0." | 1.31 | Does prolonged oral exposure to cyanide promote hepatotoxicity and nephrotoxicity? ( Górniak, SL; Guerra, JL; Kimura, ET; Soto-Blanco, B; Sousa, AB, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 8 (38.10) | 29.6817 |
| 2010's | 10 (47.62) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Terzi, F | 2 |
| Ciftci, MK | 2 |
| DeKlotz, CMC | 1 |
| Roby, KD | 1 |
| Friedlander, SF | 1 |
| Gualano, B | 1 |
| Roschel, H | 1 |
| Landry, GM | 1 |
| Dunning, CL | 1 |
| Abreo, F | 1 |
| Latimer, B | 1 |
| Orchard, E | 1 |
| McMartin, KE | 1 |
| Schnackenberg, LK | 2 |
| Chen, M | 1 |
| Sun, J | 2 |
| Holland, RD | 1 |
| Dragan, Y | 1 |
| Tong, W | 1 |
| Welsh, W | 1 |
| Beger, RD | 2 |
| Francaux, M | 1 |
| Poortmans, JR | 1 |
| Khan, SA | 1 |
| McLean, MK | 1 |
| Gwaltney-Brant, S | 1 |
| Stogov, MV | 1 |
| Luniova, SN | 1 |
| Tkachuk, EA | 1 |
| Timcheh-Hariri, A | 2 |
| Balali-Mood, M | 2 |
| Aryan, E | 2 |
| Sadeghi, M | 2 |
| Riahi-Zanjani, B | 2 |
| Kondo, K | 1 |
| Yamada, N | 1 |
| Suzuki, Y | 1 |
| Toyoda, K | 1 |
| Hashimoto, T | 1 |
| Takahashi, A | 1 |
| Kobayashi, A | 1 |
| Shoda, T | 1 |
| Kuno, H | 1 |
| Sugai, S | 1 |
| Wallimann, T | 1 |
| Tarnopolsky, MA | 1 |
| Bourgeois, JM | 1 |
| Snow, R | 1 |
| Keys, S | 1 |
| Roy, BD | 1 |
| Kwiecien, JM | 1 |
| Turnbull, J | 1 |
| FINK, HE | 1 |
| ROENIGK, WJ | 1 |
| WILSON, GP | 1 |
| Yap, IK | 1 |
| Clayton, TA | 1 |
| Tang, H | 1 |
| Everett, JR | 1 |
| Hanton, G | 1 |
| Provost, JP | 1 |
| Le Net, JL | 1 |
| Charuel, C | 1 |
| Lindon, JC | 1 |
| Nicholson, JK | 1 |
| Liao, P | 1 |
| Wei, L | 1 |
| Zhang, X | 1 |
| Li, X | 1 |
| Wu, H | 1 |
| Wu, Y | 1 |
| Ni, J | 1 |
| Pei, F | 1 |
| Borges, VC | 1 |
| Rocha, JB | 1 |
| Savegnago, L | 1 |
| Nogueira, CW | 1 |
| Sousa, AB | 1 |
| Soto-Blanco, B | 1 |
| Guerra, JL | 1 |
| Kimura, ET | 1 |
| Górniak, SL | 1 |
| de Lemos, E | 1 |
| Pariat, C | 1 |
| Piriou, A | 1 |
| Fauconneau, B | 1 |
| Courtois, P | 1 |
1 review available for creatine and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Side effects of creatine supplementation in athletes.
Topics: Administration, Oral; Athletic Performance; Chemical and Drug Induced Liver Injury; Creatine; Dietar | 2006 |
20 other studies available for creatine and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Protective effect of silymarin on tacrolimus-induced kidney and liver toxicity.
Topics: Albumins; Animals; Antioxidants; Bilirubin; Chemical and Drug Induced Liver Injury; Creatine; Hepati | 2022 |
Protective effect of silymarin on tacrolimus-induced kidney and liver toxicity.
Topics: Albumins; Animals; Antioxidants; Bilirubin; Chemical and Drug Induced Liver Injury; Creatine; Hepati | 2022 |
Protective effect of silymarin on tacrolimus-induced kidney and liver toxicity.
Topics: Albumins; Animals; Antioxidants; Bilirubin; Chemical and Drug Induced Liver Injury; Creatine; Hepati | 2022 |
Protective effect of silymarin on tacrolimus-induced kidney and liver toxicity.
Topics: Albumins; Animals; Antioxidants; Bilirubin; Chemical and Drug Induced Liver Injury; Creatine; Hepati | 2022 |
Dietary Supplements, Isotretinoin, and Liver Toxicity in Adolescents: A Retrospective Case Series.
Topics: Acne Vulgaris; Adolescent; Biomarkers; Camellia sinensis; Chemical and Drug Induced Liver Injury; Cr | 2017 |
Comment on "Toxic hepatitis in a group of 20 male body-builders taking dietary supplements" by Timcheh-Hariri et al. (2012), Food and Chemical Toxicology 50, 3826-3832: alleged adverse effects of creatine supplementation and the lack of appreciation of th
Topics: Chemical and Drug Induced Liver Injury; Creatine; Dietary Supplements; Humans; Male; Sports; Weight | 2014 |
Diethylene glycol-induced toxicities show marked threshold dose response in rats.
Topics: Acidosis; Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Urea Nitrogen; Chemical | 2015 |
Evaluations of the trans-sulfuration pathway in multiple liver toxicity studies.
Topics: Animals; Chemical and Drug Induced Liver Injury; Comet Assay; Creatine; Drug-Related Side Effects an | 2009 |
Studies of acetaminophen and metabolites in urine and their correlations with toxicity using metabolomics.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Animals; Biotransformation; Chemical | 2009 |
Accidental overdosage of joint supplements in dogs.
Topics: Animals; Chemical and Drug Induced Liver Injury; Creatine; Dietary Supplements; Dimethyl Sulfoxide; | 2010 |
Accumulation of calcium, phosphate, and collagen in bones and accumulation of creatine in muscles of mice with acute hepatic intoxication during shin fracture healing.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bone and Bones; Calcium; Carbon Tetrachl | 2010 |
Toxic hepatitis in a group of 20 male body-builders taking dietary supplements.
Topics: Adult; Amino Acids; Chemical and Drug Induced Liver Injury; Creatine; Dietary Supplements; Doping in | 2012 |
Enhancement of acetaminophen-induced chronic hepatotoxicity in restricted fed rats: a nonclinical approach to acetaminophen-induced chronic hepatotoxicity in susceptible patients.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antipyretics; Blood Glucose; | 2012 |
Comment on "toxic hepatitis in a group of 20 male body-builders taking dietary supplements" by.
Topics: Chemical and Drug Induced Liver Injury; Creatine; Dietary Supplements; Humans; Male; Sports; Weight | 2013 |
Controversy over the use of creatine as a safe dietary supplement.
Topics: Chemical and Drug Induced Liver Injury; Creatine; Dietary Supplements; Humans; Male; Sports; Weight | 2013 |
Histological assessment of intermediate- and long-term creatine monohydrate supplementation in mice and rats.
Topics: Animals; Chemical and Drug Induced Liver Injury; Creatine; Dietary Supplements; Female; Liver; Male; | 2003 |
AN EXPERIMENTAL INVESTIGATION OF THE NEPHROTOXIC EFFECTS OF ORAL CHOLECYSTOGRAPHIC AGENTS.
Topics: Bilirubin; Blood Pressure Determination; Chemical and Drug Induced Liver Injury; Cholecystography; C | 1964 |
An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate.
Topics: Animals; Blood Chemical Analysis; Chemical and Drug Induced Liver Injury; Creatine; Formic Acid Este | 2006 |
Metabolic profiling of serum from gadolinium chloride-treated rats by 1H NMR spectroscopy.
Topics: Alanine; Amino Acids; Animals; Biomarkers; Blood Glucose; Chemical and Drug Induced Liver Injury; Cr | 2007 |
Repeated administration of diphenyl ditelluride induces hematological disorders in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzene Derivatives; Body Weight; Bone M | 2007 |
Does prolonged oral exposure to cyanide promote hepatotoxicity and nephrotoxicity?
Topics: Animals; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Creatine; Cyanides; Enzymes; K | 2002 |
[Circadian variations in the nephrotoxicity of the vancomycin-gentamicin combination in rats].
Topics: Acetylglucosaminidase; Aminopeptidases; Animals; CD13 Antigens; Chemical and Drug Induced Liver Inju | 1991 |