creatine has been researched along with Cerebral Infarction in 27 studies
Cerebral Infarction: The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).
| Excerpt | Relevance | Reference |
|---|---|---|
| " We decided to administer it by intracerebroventricular infusion, to maximize its bioavailability to the brain." | 5.33 | Intracerebroventricular administration of creatine protects against damage by global cerebral ischemia in rat. ( Balestrino, M; Gandolfo, C; Izvarina, N; Korzhevskii, DE; Kostkin, VB; Lensman, M; Mourovets, VO; Otellin, VA; Perasso, L; Polenov, SA, 2006) |
| "Twelve subjects (mean age 40 years; range 26-55 years; males/females 6/6) with genetically proven CADASIL and no clinical signs of the disease underwent conventional MRI and proton MR spectroscopic imaging ((1)H-MRSI) to measure white matter (WM) lesion volume (LV), global and regional cerebral volumes, and WM levels of N-acetylaspartate (NAA) normalised to creatine (Cr)." | 3.75 | Structural and metabolic brain abnormalities in preclinical cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy. ( Battaglini, M; Bianchi, S; De Stefano, N; Dotti, MT; Federico, A; Inzitari, D; Mortilla, M; Pantoni, L; Plewnia, K; Stromillo, ML, 2009) |
| " Non-neoplastic lesions such as cerebral infarctions and brain abscesses are marked by decreases in choline (Cho), creatine (Cr) and N-acetyl-aspartate (NAA), while tumours generally have elevated Cho and decreased levels of Cr and NAA." | 3.71 | Clinical application of proton magnetic resonance spectroscopy in the diagnosis of intracranial mass lesions. ( Herminghaus, S; Krings, T; Lanfermann, H; Marquardt, G; Möller-Hartmann, W; Pilatus, U; Zanella, FE, 2002) |
| "Metabolite maps of choline-containing compounds, total creatine consisting of creatine and phosphocreatine, N-acetyl aspartate (NAA), and lactate were obtained in 23 patients with acute and subacute cerebral infarctions 1-35 days after onset of symptoms." | 3.69 | Metabolic changes in acute and subacute cerebral infarctions: findings at proton MR spectroscopic imaging. ( Heindel, W; Heiss, WD; Herholz, K; Kugel, H; Lackner, K; Lanfermann, H, 1995) |
| " First, in patients with cerebral infarctions, increased concentrations of lactate were found in the majority of patients, and N-acetyl aspartate (NAA) was reduced to a significantly greater extent than choline (Cho) or creatine (Cre)." | 3.68 | Proton magnetic resonance spectroscopy of human brain: applications to normal white matter, chronic infarction, and MRI white matter signal hyperintensities. ( Calabrese, G; Deicken, R; Fein, G; Fisher, SN; Hetherington, HP; Sappey-Marinier, D; Van Dyke, C; Weiner, MW, 1992) |
| " We decided to administer it by intracerebroventricular infusion, to maximize its bioavailability to the brain." | 1.33 | Intracerebroventricular administration of creatine protects against damage by global cerebral ischemia in rat. ( Balestrino, M; Gandolfo, C; Izvarina, N; Korzhevskii, DE; Kostkin, VB; Lensman, M; Mourovets, VO; Otellin, VA; Perasso, L; Polenov, SA, 2006) |
| "Six patients with completed cerebral infarction were examined longitudinally with localized proton magnetic resonance spectroscopy." | 1.29 | Longitudinal changes in proton magnetic resonance spectroscopy in cerebral infarction. ( Abe, H; Houkin, K; Iwasaki, Y; Kamada, K; Kamiyama, H; Kashiwaba, T, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (48.15) | 18.2507 |
| 2000's | 11 (40.74) | 29.6817 |
| 2010's | 2 (7.41) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Laredo, C | 1 |
| Rodríguez, A | 1 |
| Oleaga, L | 1 |
| Hernández-Pérez, M | 1 |
| Renú, A | 1 |
| Puig, J | 1 |
| Román, LS | 1 |
| Planas, AM | 1 |
| Urra, X | 1 |
| Chamorro, Á | 1 |
| Zhang, M | 1 |
| Sun, X | 1 |
| Zhang, Z | 1 |
| Meng, Q | 1 |
| Wang, Y | 1 |
| Chen, J | 1 |
| Ma, X | 1 |
| Geng, H | 1 |
| Sun, L | 1 |
| Stromillo, ML | 1 |
| Dotti, MT | 1 |
| Battaglini, M | 1 |
| Mortilla, M | 1 |
| Bianchi, S | 1 |
| Plewnia, K | 1 |
| Pantoni, L | 1 |
| Inzitari, D | 1 |
| Federico, A | 1 |
| De Stefano, N | 1 |
| Karaszewski, B | 1 |
| Thomas, RG | 1 |
| Chappell, FM | 1 |
| Armitage, PA | 1 |
| Carpenter, TK | 1 |
| Lymer, GK | 1 |
| Dennis, MS | 1 |
| Marshall, I | 1 |
| Wardlaw, JM | 1 |
| Lensman, M | 1 |
| Korzhevskii, DE | 1 |
| Mourovets, VO | 1 |
| Kostkin, VB | 1 |
| Izvarina, N | 1 |
| Perasso, L | 1 |
| Gandolfo, C | 1 |
| Otellin, VA | 1 |
| Polenov, SA | 1 |
| Balestrino, M | 1 |
| Glodzik-Sobanska, L | 1 |
| Slowik, A | 1 |
| McHugh, P | 1 |
| Sobiecka, B | 1 |
| Kozub, J | 1 |
| Rich, KE | 1 |
| Urbanik, A | 1 |
| Szczudlik, A | 1 |
| Saunders, DE | 1 |
| Howe, FA | 1 |
| van den Boogaart, A | 1 |
| McLean, MA | 1 |
| Griffiths, JR | 1 |
| Brown, MM | 1 |
| Lanfermann, H | 3 |
| Kugel, H | 2 |
| Heindel, W | 2 |
| Herholz, K | 1 |
| Heiss, WD | 1 |
| Lackner, K | 2 |
| Gideon, P | 2 |
| Sperling, B | 1 |
| Arlien-Søborg, P | 2 |
| Olsen, TS | 2 |
| Henriksen, O | 2 |
| Sperling, BK | 1 |
| Christiansen, P | 1 |
| Jørgensen, HS | 1 |
| Houkin, K | 1 |
| Kamada, K | 1 |
| Kamiyama, H | 1 |
| Iwasaki, Y | 1 |
| Abe, H | 1 |
| Kashiwaba, T | 1 |
| Stockhammer, G | 1 |
| Felber, SR | 1 |
| Zelger, B | 1 |
| Sepp, N | 1 |
| Birbamer, GG | 1 |
| Fritsch, PO | 1 |
| Aichner, FT | 1 |
| Landwehr, P | 1 |
| Krahe, T | 1 |
| Lauriero, F | 1 |
| Federico, F | 1 |
| Rubini, G | 1 |
| Conte, C | 1 |
| Simone, I | 1 |
| Inchingolo, V | 1 |
| d'Addabbo, A | 1 |
| Dreher, W | 1 |
| Kühn, B | 1 |
| Gyngell, ML | 1 |
| Busch, E | 1 |
| Niendorf, T | 1 |
| Hossmann, KA | 1 |
| Leibfritz, D | 1 |
| Lei, H | 1 |
| Peeling, J | 1 |
| Abe, O | 1 |
| Okubo, T | 1 |
| Hayashi, N | 1 |
| Saito, N | 1 |
| Iriguchi, N | 1 |
| Shirouzu, I | 1 |
| Kojima, Y | 1 |
| Masumoto, T | 1 |
| Ohtomo, K | 1 |
| Sasaki, Y | 1 |
| Kang, DW | 1 |
| Roh, JK | 1 |
| Lee, YS | 1 |
| Song, IC | 1 |
| Yoon, BW | 1 |
| Chang, KH | 1 |
| Rumpel, H | 1 |
| Khoo, JB | 1 |
| Chang, HM | 1 |
| Lim, WE | 1 |
| Chen, C | 1 |
| Wong, MC | 1 |
| Tan, KP | 1 |
| Kim, GE | 1 |
| Lee, JH | 1 |
| Cho, YP | 1 |
| Kim, ST | 1 |
| Kimura, T | 1 |
| Sako, K | 1 |
| Gotoh, T | 1 |
| Tanaka, K | 1 |
| Tanaka, T | 1 |
| Harada, M | 1 |
| Uno, M | 1 |
| Hong, F | 1 |
| Hisaoka, S | 1 |
| Nishitani, H | 1 |
| Matsuda, T | 1 |
| Chu, WJ | 1 |
| Mason, GF | 1 |
| Pan, JW | 1 |
| Hetherington, HP | 2 |
| Liu, HG | 1 |
| San Pedro, EC | 1 |
| Mountz, JM | 1 |
| Möller-Hartmann, W | 1 |
| Herminghaus, S | 1 |
| Krings, T | 1 |
| Marquardt, G | 1 |
| Pilatus, U | 1 |
| Zanella, FE | 1 |
| Wang, Z | 1 |
| Bogdan, AR | 1 |
| Zimmerman, RA | 1 |
| Gusnard, DA | 1 |
| Leigh, JS | 1 |
| Ohene-Frempong, K | 1 |
| Sappey-Marinier, D | 1 |
| Calabrese, G | 1 |
| Fisher, SN | 1 |
| Deicken, R | 1 |
| Van Dyke, C | 1 |
| Fein, G | 1 |
| Weiner, MW | 2 |
| Duijn, JH | 1 |
| Matson, GB | 1 |
| Maudsley, AA | 1 |
| Hugg, JW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| CHemical OptImization of Cerebral Embolectomy in Patients With Acute Stroke Treated With Mechanical Thrombectomy 2 (CHOICE 2 TRIAL)[NCT05797792] | Phase 3 | 440 participants (Anticipated) | Interventional | 2023-06-01 | Not yet recruiting | ||
| MRI for Early Identification of Underlying Pathology in Patients With Acute Intracerebral Hemorrhage[NCT01689402] | 60 participants (Actual) | Observational | 2012-04-30 | Completed | |||
| Remote Effects of Stroke on Cerebral Metabolism. Evaluation With Positron Emission Tomography and Proton Magnetic Resonance Spectroscopy[NCT00063180] | 70 participants | Observational | 2003-06-19 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for creatine and Cerebral Infarction
| Article | Year |
|---|---|
Adjunct Thrombolysis Enhances Brain Reperfusion following Successful Thrombectomy.
Topics: Aged; Aged, 80 and over; Brain; Brain Ischemia; Cerebral Infarction; Creatine; Endovascular Procedur | 2022 |
Neuronal metabolic changes in the cortical region after subcortical infarction: a proton MR spectroscopy study.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Cerebral Angiography; Cerebral Cortex; Cerebral Infar | 2000 |
Regional cerebral blood flow and magnetic resonance spectroscopic imaging findings in diaschisis from stroke.
Topics: Adult; Aged; Aspartic Acid; Blood Flow Velocity; Brain; Cerebral Infarction; Cerebrovascular Circula | 2002 |
24 other studies available for creatine and Cerebral Infarction
| Article | Year |
|---|---|
Brain metabolite changes in patients with type 2 diabetes and cerebral infarction using proton magnetic resonance spectroscopy.
Topics: Aged; Aspartic Acid; Blood Glucose; Brain; Cerebral Infarction; Choline; Creatine; Diabetes Mellitus | 2014 |
Structural and metabolic brain abnormalities in preclinical cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy.
Topics: Adult; Age Factors; Aspartic Acid; CADASIL; Cerebral Infarction; Creatine; Female; Frontal Lobe; Hum | 2009 |
Brain choline concentration. Early quantitative marker of ischemia and infarct expansion?
Topics: Aged; Aged, 80 and over; Brain; Brain Ischemia; Brain Mapping; Cerebral Infarction; Choline; Creatin | 2010 |
Intracerebroventricular administration of creatine protects against damage by global cerebral ischemia in rat.
Topics: Animals; Brain Ischemia; Cerebral Infarction; Creatine; Disease Models, Animal; Drug Administration | 2006 |
Single voxel proton magnetic resonance spectroscopy in post-stroke depression.
Topics: Aged; Aspartic Acid; Cerebral Infarction; Choline; Creatine; Depressive Disorder; Dominance, Cerebra | 2006 |
Continuing ischemic damage after acute middle cerebral artery infarction in humans demonstrated by short-echo proton spectroscopy.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain; Cerebral Arteries; Cerebral Infarction; Cholin | 1995 |
Metabolic changes in acute and subacute cerebral infarctions: findings at proton MR spectroscopic imaging.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain; Cerebral Infarction; Choline; C | 1995 |
Long-term follow-up of cerebral infarction patients with proton magnetic resonance spectroscopy.
Topics: Adult; Aged; Aspartic Acid; Brain; Cerebral Infarction; Creatine; Female; Follow-Up Studies; Humans; | 1994 |
[Magnetic resonance spectroscopy of acute cerebral infarctions].
Topics: Acute Disease; Adult; Aged; Aspartic Acid; Cerebral Infarction; Choline; Creatine; Humans; Magnetic | 1993 |
Longitudinal changes in proton magnetic resonance spectroscopy in cerebral infarction.
Topics: Adult; Aspartic Acid; Brain; Cerebral Infarction; Choline; Creatine; Female; Humans; Lactates; Magne | 1993 |
Sneddon's syndrome: diagnosis by skin biopsy and MRI in 17 patients.
Topics: Adolescent; Adult; Angiography; Arteries; Biopsy; Cerebral Infarction; Cerebrovascular Disorders; Cr | 1993 |
[Spectroscopic imaging of the brain. Examination technique and clinical applications].
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Cerebral Infarction; Choline; Creatine; Energy M | 1995 |
99Tcm-HMPAO SPET and 1H-MRS (proton magnetic resonance spectroscopy) in patients with ischaemic cerebral infarction.
Topics: Adult; Aged; Aspartic Acid; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circulation; Cholin | 1996 |
Temporal and regional changes during focal ischemia in rat brain studied by proton spectroscopic imaging and quantitative diffusion NMR imaging.
Topics: Animals; Aspartic Acid; Blood Glucose; Cerebral Infarction; Creatine; Diffusion; Dominance, Cerebral | 1998 |
Multiple-voxel double-quantum lactate-edited spectroscopy using two-dimensional longitudinal Hadamard encoding.
Topics: Animals; Artifacts; Aspartic Acid; Brain; Cerebral Infarction; Choline; Creatine; Image Processing, | 1999 |
Temporal changes of the apparent diffusion coefficients of water and metabolites in rats with hemispheric infarction: experimental study of transhemispheric diaschisis in the contralateral hemisphere at 7 tesla.
Topics: Animals; Aspartic Acid; Brain; Cerebral Infarction; Choline; Creatine; Diffusion; Magnetic Resonance | 2000 |
Correlation of the apparent diffusion coefficient and the creatine level in early ischemic stroke: a comparison of different patterns by magnetic resonance.
Topics: Adult; Aged; Brain; Brain Mapping; Cerebral Infarction; Creatine; Diffusion; Dominance, Cerebral; Ec | 2001 |
Metabolic changes in the ischemic penumbra after carotid endarterectomy in stroke patients by localized in vivo proton magnetic resonance spectroscopy (1H-MRS).
Topics: Aged; Aspartic Acid; Brain Ischemia; Carotid Stenosis; Cerebral Infarction; Choline; Creatine; Endar | 2001 |
In vivo single-voxel proton MR spectroscopy in brain lesions with ring-like enhancement.
Topics: Adult; Aged; Brain; Brain Abscess; Brain Diseases; Brain Neoplasms; Cerebral Infarction; Choline; Cr | 2001 |
Diffusion-weighted in vivo localized proton MR spectroscopy of human cerebral ischemia and tumor.
Topics: Adult; Aspartic Acid; Brain Ischemia; Brain Neoplasms; Cerebral Infarction; Creatine; Diffusion; Fem | 2002 |
Clinical application of proton magnetic resonance spectroscopy in the diagnosis of intracranial mass lesions.
Topics: Aspartic Acid; Brain Abscess; Brain Neoplasms; Cerebral Infarction; Choline; Creatine; Diagnosis, Di | 2002 |
Investigation of stroke in sickle cell disease by 1H nuclear magnetic resonance spectroscopy.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Aspartic Acid; Atrophy; Brain; Brain Ischemia; Cerebral Infa | 1992 |
Proton magnetic resonance spectroscopy of human brain: applications to normal white matter, chronic infarction, and MRI white matter signal hyperintensities.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Chemistry; Brain Ischemia; Cerebral Infarction; | 1992 |
Human brain infarction: proton MR spectroscopy.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain; Cerebral Infarction; Choline; Creatine; Humans | 1992 |