creatine has been researched along with Cardiomegaly in 16 studies
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cysteine oxidative modification of cellular proteins is crucial for many aspects of cardiac hypertrophy development." | 7.88 | Integrated Dissection of Cysteine Oxidative Post-translational Modification Proteome During Cardiac Hypertrophy. ( Cao, Q; Choi, H; Chung, NC; Garlid, AO; Mirza, B; Ng, DCM; Ping, P; Scruggs, SB; Wang, D; Wang, J, 2018) |
| " Primary outcome measures were mitochondrial ATP production measured as phosphocreatine recovery by 31Phosphorus magnetic resonance spectroscopy, neurological deficits assessed by the international co-operative ataxia rating scale and cardiac hypertrophy in echocardiography." | 5.11 | L-carnitine and creatine in Friedreich's ataxia. A randomized, placebo-controlled crossover trial. ( Abele, M; Colier, WN; Klockgether, T; Kuntz-Hehner, S; Müller, K; Przuntek, H; Schillings, M; Schöls, L; Skipka, G; van Beekvelt, MC; Vorgerd, M; Zange, J, 2005) |
| "Cysteine oxidative modification of cellular proteins is crucial for many aspects of cardiac hypertrophy development." | 3.88 | Integrated Dissection of Cysteine Oxidative Post-translational Modification Proteome During Cardiac Hypertrophy. ( Cao, Q; Choi, H; Chung, NC; Garlid, AO; Mirza, B; Ng, DCM; Ping, P; Scruggs, SB; Wang, D; Wang, J, 2018) |
| "To address the hypothesis that impaired ATP synthesis rates caused by changes in the creatine kinase system is an important mechanism underlying cardiac failure, we measured total creatine kinase activity, isoenzyme composition and creatine content in two animal models of hypertrophy with cardiac dysfunction, the spontaneously hypertensive rat in the transition to failure and the creatine-depleted hyperthyroid rat heart challenged by hypoxia." | 3.68 | Energetic correlates of cardiac failure: changes in the creatine kinase system in the failing myocardium. ( Atkinson, DE; Clarke, K; Fetters, JK; Ingwall, JS, 1990) |
| "We measured creatine kinase activity, isozyme composition, and total creatine content in biopsy samples of left ventricular myocardium from 34 adults in four groups: subjects with normal left ventricles, patients with left ventricular hypertrophy due to aortic stenosis, patients with coronary artery disease without left ventricular hypertrophy, and patients with coronary artery disease and left ventricular hypertrophy due to aortic stenosis." | 3.67 | The creatine kinase system in normal and diseased human myocardium. ( Allen, PD; Fifer, MA; Grossman, W; Ingwall, JS; Kramer, MF; Lorell, BH; Shemin, R, 1985) |
| " Chronic administration of oxfenicine to dogs for 1 year produced dose-related, nonpathological increases in relative heart weight (up to 85% at 750 mg/kg per day)." | 1.27 | Coronary hyperemia and cardiac hypertrophy following inhibition of fatty acid oxidation. Evidence of a regulatory role for cytosolic phosphorylation potential. ( Faccini, JM; Greaves, P; Higgins, AJ, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (50.00) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, J | 1 |
| Choi, H | 1 |
| Chung, NC | 1 |
| Cao, Q | 1 |
| Ng, DCM | 1 |
| Mirza, B | 1 |
| Scruggs, SB | 1 |
| Wang, D | 1 |
| Garlid, AO | 1 |
| Ping, P | 1 |
| Phillips, D | 1 |
| Ten Hove, M | 1 |
| Schneider, JE | 1 |
| Wu, CO | 1 |
| Sebag-Montefiore, L | 1 |
| Aponte, AM | 1 |
| Lygate, CA | 1 |
| Wallis, J | 1 |
| Clarke, K | 2 |
| Watkins, H | 1 |
| Balaban, RS | 1 |
| Neubauer, S | 1 |
| Shen, W | 1 |
| Vatner, DE | 1 |
| Vatner, SF | 1 |
| Ingwall, JS | 4 |
| GANGLOFF, EC | 1 |
| HEMMINGS, IL | 1 |
| KRAUSE, RF | 1 |
| JOHNSTON, LC | 1 |
| GRIEBLE, HG | 1 |
| SCHOENBERGER, JA | 1 |
| FULLER, JB | 1 |
| FOX, AC | 1 |
| WIKLER, NS | 1 |
| REED, GE | 1 |
| Schöls, L | 1 |
| Zange, J | 1 |
| Abele, M | 1 |
| Schillings, M | 1 |
| Skipka, G | 1 |
| Kuntz-Hehner, S | 1 |
| van Beekvelt, MC | 1 |
| Colier, WN | 1 |
| Müller, K | 1 |
| Klockgether, T | 1 |
| Przuntek, H | 1 |
| Vorgerd, M | 1 |
| Srivastava, PM | 1 |
| Calafiore, P | 1 |
| Macisaac, RJ | 1 |
| Patel, SK | 1 |
| Thomas, MC | 1 |
| Jerums, G | 1 |
| Burrell, LM | 1 |
| Ben Cheikh, R | 1 |
| Guendouz, A | 1 |
| Moravec, J | 1 |
| Lortet, S | 1 |
| Heckmann, M | 1 |
| Ray, A | 1 |
| Rossi, A | 1 |
| Aussedat, J | 1 |
| Grably, S | 1 |
| Zimmer, HG | 1 |
| Morales, MF | 1 |
| Stockdale, FE | 1 |
| Wildenthal, K | 1 |
| Reilly, PJ | 1 |
| Cooksey, JD | 1 |
| Atkinson, DE | 1 |
| Fetters, JK | 1 |
| Kramer, MF | 1 |
| Fifer, MA | 1 |
| Lorell, BH | 1 |
| Shemin, R | 1 |
| Grossman, W | 1 |
| Allen, PD | 1 |
| Siehl, D | 1 |
| Chua, BH | 1 |
| Lautensack-Belser, N | 1 |
| Morgan, HE | 1 |
| Higgins, AJ | 1 |
| Faccini, JM | 1 |
| Greaves, P | 1 |
1 trial available for creatine and Cardiomegaly
| Article | Year |
|---|---|
L-carnitine and creatine in Friedreich's ataxia. A randomized, placebo-controlled crossover trial.
Topics: Adenosine Triphosphate; Adolescent; Adult; Cardiomegaly; Carnitine; Child; Creatine; Female; Friedre | 2005 |
15 other studies available for creatine and Cardiomegaly
| Article | Year |
|---|---|
Integrated Dissection of Cysteine Oxidative Post-translational Modification Proteome During Cardiac Hypertrophy.
Topics: Calcium; Cardiomegaly; Creatine; Cysteine; Glucose; Humans; Oxidation-Reduction; Phosphorylation; Pr | 2018 |
Mice over-expressing the myocardial creatine transporter develop progressive heart failure and show decreased glycolytic capacity.
Topics: Animals; Aorta; Cardiomegaly; Creatine; Electrophoresis, Gel, Two-Dimensional; Female; Glycolysis; H | 2010 |
Progressive loss of creatine maintains a near normal DeltaG approximately (ATP) in transgenic mouse hearts with cardiomyopathy caused by overexpressing Gsalpha.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cardiomegaly; Cardiomyopathies; Creatine; Cy | 2010 |
Creatine, creatinine, and creatine phosphate in normal and hypertrophied rat hearts.
Topics: Cardiomegaly; Coenzymes; Creatine; Creatinine; Hypertrophy; Phosphocreatine | 1961 |
TREATMENT OF ARTERIAL HYPERTENSIVE DISEASE WITH DIURETICS. III. CHLORTHALIDONE ALONE AND IN COMBINATION WITH SPIRONOLACTONE.
Topics: Bendroflumethiazide; Cardiomegaly; Chlorides; Chlorthalidone; Coronary Disease; Creatine; Creatinine | 1964 |
HIGH ENERGY PHOSPHATE COMPOUNDS IN THE MYOCARDIUM DURING EXPERIMENTAL CONGESTIVE HEART FAILURE. PURINE AND PYRIMIDINE NUCLEOTIDES, CREATINE, AND CREATINE PHOSPHATE IN NORMAL AND IN FAILING HEARTS.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Biochemical Phenomena; Biochemistry; Cardiomeg | 1965 |
Prevalence and predictors of cardiac hypertrophy and dysfunction in patients with Type 2 diabetes.
Topics: Aging; Analysis of Variance; Antihypertensive Agents; Cardiomegaly; Creatine; Cross-Sectional Studie | 2008 |
Control of oxidative metabolism in volume-overloaded rat hearts: effects of different lipid substrates.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Caprylates; Cardiomegaly; Creatine; Energy M | 1994 |
Energy metabolism response to calcium activation in isolated rat hearts during development and regression of T3-induced hypertrophy.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cardiomegaly; Creatine; Energy Meta | 1995 |
Creatine: a possible stimulus skeletal cardiac muscle hypertrophy.
Topics: Actins; Animals; Cardiomegaly; Chick Embryo; Creatine; Culture Techniques; DNA; Hypertrophy; Leucine | 1975 |
Cardiac energy stores and creatine in experimental cardiac hypertrophy.
Topics: Adenosine Triphosphate; Animals; Cardiomegaly; Creatine; Female; Heart Ventricles; Myocardium; Phosp | 1979 |
Energetic correlates of cardiac failure: changes in the creatine kinase system in the failing myocardium.
Topics: Animals; Cardiac Output, Low; Cardiomegaly; Creatine; Creatine Kinase; Hypoxia; Isoenzymes; Mitochon | 1990 |
The creatine kinase system in normal and diseased human myocardium.
Topics: Adult; Aged; Aortic Valve Stenosis; Cardiomegaly; Citrate (si)-Synthase; Coronary Disease; Creatine; | 1985 |
Faster protein and ribosome synthesis in thyroxine-induced hypertrophy of rat heart.
Topics: Adenine Nucleotides; Amino Acids; Animals; Cardiomegaly; Creatine; Female; Insulin; Perfusion; Phosp | 1985 |
Coronary hyperemia and cardiac hypertrophy following inhibition of fatty acid oxidation. Evidence of a regulatory role for cytosolic phosphorylation potential.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cardiomegaly; Coronary Circulation; Creatine | 1985 |