Page last updated: 2024-10-17

creatine and Cancer of Prostate

creatine has been researched along with Cancer of Prostate in 56 studies

Research Excerpts

ExcerptRelevanceReference
" The (choline + creatine)/ citrate values in regions of histologically confirmed benign prostatic hyperplasia (0."3.69Prostate cancer: metabolic response to cryosurgery as detected with 3D H-1 MR spectroscopic imaging. ( Carroll, PR; Hricak, H; Kurhanewicz, J; Nelson, SJ; Parivar, F; Shinohara, K; Vigneron, DB, 1996)
"Prostate cancer is a major health problem, and the exploration of noninvasive imaging methods that have the potential to improve specificity while maintaining high sensitivity is still critically needed."2.44Diffusion-weighted imaging with apparent diffusion coefficient mapping and spectroscopy in prostate cancer. ( Jacobs, MA; Macura, KJ; Ouwerkerk, R; Petrowski, K, 2008)
"When MRS and MR imaging agree on prostate cancer presence, the positive predictive value is about 80-90%."2.44Proton MR spectroscopy of the prostate. ( Mueller-Lisse, UG; Scherr, MK, 2007)
"Creatine treatment was associated with enhanced cellular basal respiration in vitro and increased tumor cell proliferation in vivo."1.72Cyclocreatine Suppresses Creatine Metabolism and Impairs Prostate Cancer Progression. ( Fleming, J; Ford, CA; Leung, HY; Lynch, V; Mackay, G; Mui, E; Patel, R; Rodgers, L; Rushworth, LK; Sansom, OJ; Sumpton, D; Vande Voorde, J; Watson, D; Zhang, T, 2022)
"Fifty-seven prostate cancer patients underwent an MR examination followed by prostatectomy."1.43Contribution of Histopathologic Tissue Composition to Quantitative MR Spectroscopy and Diffusion-weighted Imaging of the Prostate. ( Bruggink, CC; Hambrock, T; Heerschap, A; Hulsbergen-van de Kaa, CA; Kobus, T; Maas, MC; Scheenen, TW; van der Laak, JA, 2016)
"Prostate cancer is common and may be treated immediately or managed conservatively by observation."1.40Multiparametric 3T MRI in the evaluation of intraglandular prostate cancer: correlation with histopathology. ( Bergen, N; Duchesne, G; Ferris, N; Frydenberg, M; Mills, J; Mitchell, C; Murphy, D; Pedersen, J; Styles, C, 2014)
"Gold seeds cause small effects (in the order of the standard deviation) on the ratio of the metabolite's CC/Ci in the phantom study done on a 1."1.38Effect of gold marker seeds on magnetic resonance spectroscopy of the prostate. ( Buyyounouski, MK; Chen, L; Hossain, M; Ma, CM; Richardson, T; Schirmer, T, 2012)
"This supports long-term HT in advanced prostate cancer."1.38Locally advanced prostate cancer: three-dimensional magnetic resonance spectroscopy to monitor prostate response to therapy. ( Bonomo, P; Clementi, V; D'Agostino, GR; Di Molfetta, IV; Gui, B; Mantini, G; Mattiucci, G; Valentini, AL, 2012)
"Thirty-eight patients with prostate cancer (PCa) and thirty-three patients with benign prostate hyperplasia (BPH) were included in this study."1.361H-MRSI of prostate cancer: the relationship between metabolite ratio and tumor proliferation. ( Gao, ZQ; Liu, JG; Liu, ZQ; Niu, QL; Sun, ZK; Wang, B; Wang, XZ; Yuan, YX, 2010)
"In 14 prostate cancer patients who had a final pathologic Gleason scores of i) (3 + 4 = 7, n = 7) and ii) (4 + 3 = 7, n = 7), the metabolite ratios (mean +/- SD) of (Cho + Cr)/Cit and (Cho + Cr)/Spm were calculated using the 2D JPRESS spectra as follows: i) (1."1.36Correlation of endorectal 2D JPRESS findings with pathological Gleason scores in prostate cancer patients. ( Gomez, AM; Margolis, DJ; McClure, T; Nagarajan, R; Raman, SS; Thomas, MA, 2010)
"Time-intensity curves were obtained for prostatic cancer and healthy PZ and CG from DCE-MRI."1.35Combined morphological, [1H]-MR spectroscopic and contrast-enhanced imaging of human prostate cancer with a 3-Tesla scanner: preliminary experience. ( Bonanno, E; Carlani, M; Finazzi Agrò, E; Mancino, S; Simonetti, G, 2008)
" The present study aimed to clarify the utility of 11C-choline PET for localising and evaluating cancer lesions in patients with prostate cancer by conducting a prospective comparison with magnetic resonance (MR) imaging combined with proton MR spectroscopy."1.33Prostate cancer: a comparative study of 11C-choline PET and MR imaging combined with proton MR spectroscopy. ( Endou, H; Inoue, T; Kubota, Y; Lee, J; Oka, T; Sasaki, T; Shizukuishi, K; Takahashi, N; Uemura, H; Yamaguchi, T, 2005)
"Dunning rat prostate cancer cells were injected into the prostate by open surgery."1.32Dynamic magnetic resonance tomography and proton magnetic resonance spectroscopy of prostate cancers in rats treated by radiotherapy. ( Fink, C; Grobholz, R; Heilmann, M; Huber, PE; Kiessling, F; Krix, M; Lichy, MP; Meding, J; Peschke, P; Schlemmer, HP, 2004)
"Four well-established human prostate cancer cell lines were therefore studied with magnetic resonance spectroscopy to compare differences in metabolic content with tumor biological behavior."1.29In vitro proton magnetic resonance spectroscopy of four human prostate cancer cell lines. ( Cornel, EB; de Ruijter, JE; Debruyne, FM; Heerschap, A; Oosterhof, GO; Schalken, JA; Smits, GA, 1995)
"An estimate of the spatial extent of prostate cancer was determined by generating metabolite images in which this metabolite ratio significantly exceeded normal peripheral zone values in multiple contiguous sections."1.29Three-dimensional H-1 MR spectroscopic imaging of the in situ human prostate with high (0.24-0.7-cm3) spatial resolution. ( Carroll, P; Hricak, H; Kurhanewicz, J; Narayan, P; Nelson, SJ; Vigneron, DB, 1996)
"Seven patients were diagnosed with prostate cancer, 13 with benign prostatic hypertrophy, and 3 with both conditions."1.28Differentiation of human prostate cancer from benign hypertrophy by in vitro 1H NMR. ( Dalrymple, GV; Finkbeiner, AE; Fowler, AH; Holder, JC; Komoroski, RA; Mullins, MS; Pappas, AA; Sprigg, JR, 1992)
"In patients with breast and prostate cancer hormone excretion patterns differ in a similar way from patterns in persons without cancer."1.24HORMONE EXCRETION PATTERNS IN BREAST AND PROSTATE CANCER ARE ABNORMAL. ( HOPKINS, CE; MARMORSTON, J; STERN, E; WEINER, JM, 1964)

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-19907 (12.50)18.7374
1990's6 (10.71)18.2507
2000's17 (30.36)29.6817
2010's24 (42.86)24.3611
2020's2 (3.57)2.80

Authors

AuthorsStudies
Patel, R1
Ford, CA1
Rodgers, L1
Rushworth, LK1
Fleming, J1
Mui, E1
Zhang, T1
Watson, D1
Lynch, V1
Mackay, G1
Sumpton, D1
Sansom, OJ1
Vande Voorde, J1
Leung, HY1
Reesink, DJ1
Arteaga de Castro, CS1
Van der Velden, T1
Van Vooren, J1
Oost, P1
Jonges, TGN1
Lam, MGEH1
de Keizer, B1
Willemse, PM1
Meijer, RP1
Klomp, DWJ1
Fairman, CM1
Kendall, KL1
Newton, RU1
Hart, NH1
Taaffe, DR1
Chee, R1
Tang, CI1
Galvão, DA1
Mazaheri, Y1
Shukla-Dave, A3
Goldman, DA1
Moskowitz, CS1
Takeda, T1
Reuter, VE3
Akin, O1
Hricak, H5
Zhang, VY1
Westphalen, A1
Delos Santos, L1
Tabatabai, ZL1
Shinohara, K2
Vigneron, DB3
Kurhanewicz, J5
Weis, J2
Ortiz-Nieto, F2
Ahlström, H2
Sarkar, BK1
Chakraborty, C1
Sharma, AR1
Bae, KJ1
Sharma, G1
Doss, GP1
Dutta, D1
Ding, S1
Ganbold, B1
Nam, JS1
Lee, SS1
Styles, C1
Ferris, N1
Mitchell, C1
Murphy, D1
Frydenberg, M1
Mills, J1
Pedersen, J1
Bergen, N1
Duchesne, G1
Zbýň, Š1
Krššák, M1
Memarsadeghi, M1
Gholami, B1
Haitel, A1
Weber, M1
Helbich, TH1
Trattnig, S1
Moser, E1
Gruber, S1
Kobus, T2
van der Laak, JA1
Maas, MC1
Hambrock, T2
Bruggink, CC1
Hulsbergen-van de Kaa, CA2
Scheenen, TW4
Heerschap, A5
Bellomo, G1
Marcocci, F1
Bianchini, D1
Mezzenga, E1
D'Errico, V1
Menghi, E1
Zannoli, R1
Sarnelli, A1
Hlavcak, P1
Häggman, M1
Bergman, A1
Thomas, MA3
Lange, T1
Velan, SS1
Nagarajan, R2
Raman, S1
Gomez, A1
Margolis, D2
Swart, S1
Raylman, RR1
Schulte, RF1
Boesiger, P1
Brame, RS1
Zaider, M1
Zakian, KL2
Koutcher, JA2
Zelefsky, MJ1
Scardino, PT2
Wang, XZ1
Wang, B1
Gao, ZQ1
Liu, JG1
Liu, ZQ1
Niu, QL1
Sun, ZK1
Yuan, YX1
Near, J1
Romagnoli, C1
Bartha, R1
Jacobs, MA1
Ouwerkerk, R1
Petrowski, K1
Macura, KJ1
Giusti, S1
Caramella, D1
Fruzzetti, E1
Lazzereschi, M1
Tognetti, A1
Bartolozzi, C1
Gomez, AM1
Raman, SS1
Margolis, DJ1
McClure, T1
Kirilova, A1
Damyanovich, A1
Crook, J1
Jezioranski, J1
Wallace, K1
Pintilie, M1
Verma, S1
Rajesh, A1
Fütterer, JJ1
Turkbey, B1
Pang, Y1
Choyke, PL1
Créhange, G2
Parfait, S1
Liegard, M1
Maingon, P1
Ben Salem, D1
Cochet, A1
Funes de la Vega, M1
Cormier, L1
Bonnetain, F1
Mirjolet, C1
Brunotte, F2
Walker, PM1
Klomp, DW1
Arteaga, CS1
van Asten, J1
Boer, VO1
Luijten, PR1
García-Martín, ML1
Adrados, M1
Ortega, MP1
Fernández González, I1
López-Larrubia, P1
Viaño, J2
García-Segura, JM2
Wright, AJ2
Barentsz, JO1
Buydens, LM1
Hossain, M1
Schirmer, T1
Richardson, T1
Chen, L1
Buyyounouski, MK1
Ma, CM1
Geethanath, S1
Baek, HM1
Ganji, SK1
Ding, Y1
Maher, EA1
Sims, RD1
Choi, C1
Lewis, MA1
Kodibagkar, VD1
Valentini, AL1
Gui, B1
D'Agostino, GR1
Mattiucci, G1
Clementi, V1
Di Molfetta, IV1
Bonomo, P1
Mantini, G1
Walker, P1
Provent, P1
Tizon, X1
Duchamp, O1
Genne, P1
Selnaes, KM1
Gribbestad, IS1
Bertilsson, H1
Wright, A1
Angelsen, A1
Tessem, MB1
Yue, K1
Marumoto, A1
Binesh, N1
Kaji, Y1
Wada, A1
Imaoka, I1
Matsuo, M1
Terachi, T1
Kobashi, Y1
Sugimura, K1
Fujii, M1
Maruyama, K1
Takizawa, O1
Mueller-Lisse, UG2
Scherr, M1
Eberhardt, S1
Kleinman, S1
Muruganandham, M1
Sircar, K1
Kattan, MW1
HAHNEMANN, S1
FRIIS, T1
STERN, E2
HOPKINS, CE2
WEINER, JM1
MARMORSTON, J2
MARSHALL, S1
LOMBARDO, LJ1
MYERS, SM1
GIERSON, H1
Kumar, R1
Kumar, M1
Jagannathan, NR1
Gupta, NP1
Hemal, AK1
Kiessling, F1
Huber, PE1
Grobholz, R1
Heilmann, M1
Meding, J1
Lichy, MP1
Fink, C1
Krix, M1
Peschke, P1
Schlemmer, HP1
Kim, DH1
Xing, L1
Daniel, B1
Spielman, D1
Yamaguchi, T1
Lee, J1
Uemura, H1
Sasaki, T1
Takahashi, N1
Oka, T1
Shizukuishi, K1
Endou, H1
Kubota, Y1
Inoue, T1
Hom, JJ1
Coakley, FV1
Simko, JP1
Lu, Y1
Qayyum, A1
Westphalen, AC1
Schmitt, LD1
Carroll, PR2
Scherr, MK1
Carlani, M1
Mancino, S1
Bonanno, E1
Finazzi Agrò, E1
Simonetti, G1
Nemoto, S1
Rinsho, K1
Cornel, EB1
Smits, GA1
de Ruijter, JE1
Oosterhof, GO1
Debruyne, FM1
Schalken, JA1
Narayan, P1
Carroll, P1
Nelson, SJ2
Parivar, F1
Mulvaney, PT1
Stracke, ML1
Nam, SW1
Woodhouse, E1
O'Keefe, M1
Clair, T1
Liotta, LA1
Khaddurah-Daouk, R1
Schiffmann, E1
Sánchez-Chapado, M1
Ibarburen, C1
Angulo, JC1
González, J1
Rodríguez-Vallejo, JM1
Stanka, M1
Eltze, E1
Semjonow, A1
Sievert, KD1
Maier, A1
Pfleiderer, B1
Fowler, AH1
Pappas, AA1
Holder, JC1
Finkbeiner, AE1
Dalrymple, GV1
Mullins, MS1
Sprigg, JR1
Komoroski, RA1
Guzzo, CE1
Pachas, WN1
Pinals, RS1
Krant, MJ1
Pitton, JS1
Roch, P1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Creatine Supplementation and Resistance Training in Patients With Breast Cancer (CaRTiC Study)[NCT05878106]120 participants (Anticipated)Interventional2024-01-08Not yet recruiting
Clinical Value of [18]Fluoroethylcholine Positron-Emission-Tomography Combined With Endorectal Magnetic Resonance Imaging by Software Fusion for Pre-therapeutic Staging of Prostate Cancer[NCT00520546]Phase 344 participants (Actual)Interventional2007-12-31Completed
Trans-Rectal Placement of Prostatic Fiducial Markers Under MR-Guidance in Patients Receiving External Beam Radiotherapy for Prostate Cancer: A Pilot Study[NCT00061347]Phase 115 participants (Actual)Interventional2003-05-23Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Lesion Based Analysis of FEC-PET, Endorectal MRI and Combined FEC-PET/eMRI in All Patients

PET positive lesions (n=128) were measured on its own and evaluated as malignant just as hypointense lesions on MRI. In PET/MRI analysis, MRI suspect lesions without FEC uptake were considered not to be malignant. PET positive lesions in central periurethral zone with inhomogenous signal intensity and sharp edges on MRI images were also considered to be benign. PET positive lesions in the peripheral zone without a hypointense correlate on MRI were considered to be malignant. Sensitivity, specificity, accuracy, negative and positive predictive values were determined. (NCT00520546)
Timeframe: within < 2 weeks after PET/MRI

,,
Interventionlesions (Number)
True positiveFalse positiveTrue negativeFalse negativeTotal trueTotal false
FEC-PET592619247850
Magnetic Resonance Imaging (MRI)402718435870
PET/MRI55837289236

Lesion Based Analysis of FEC-PET, Endorectal MRI and Combined FEC-PET/eMRI in Patients With Gleason Score >6 (3+3)

PET positive lesions in patients with Gleason >6(3+3),n=43 were measured on its own and evaluated as malignant just as hypointense lesions on MRI. In PET/MRI analysis, MRI suspect lesions without FEC uptake were considered not to be malignant. PET positive lesions in central periurethral zone with inhomogenous signal intensity and sharp edges on MRI images were also considered to be benign. PET positive lesions in the peripheral zone without a hypointense correlate on MRI were considered to be malignant. Sensitivity, specificity, accuracy, negative & positive predictive values were determined. (NCT00520546)
Timeframe: within < 2 weeks after PET/MRI

,,
Interventionlesions (Number)
True positiveFalse positiveTrue negativeFalse negativeTotal trueTotal false
FEC-PET27583358
Magnetic Resonance Imaging (MRI)229482617
PET/MRI271114385

Lesion Based Analysis of FEC-PET, Endorectal MRI and Combined FEC-PET/eMRI in Patients With Malignant Lesions >5mm (n=98)

PET positive lesions were measured on its own and evaluated as malignant just as hypointense lesions on MRI. In PET/MRI analysis, MRI suspect lesions without FEC uptake were considered not to be malignant. PET positive lesions in central periurethral zone with inhomogenous signal intensity and sharp edges on MRI images were also considered to be benign. PET positive lesions in the peripheral zone without a hypointense correlate on MRI were considered to be malignant. Sensitivity, specificity, accuracy, negative and positive predictive values were determined without malign lesions <=5mm. (NCT00520546)
Timeframe: within < 2 weeks after PET/MRI

,,
Interventionlesions (Number)
True positiveFalse positiveTrue negativeFalse negativeTotal trueTotal false
FEC-PET48241886632
Magnetic Resonance Imaging (MRI)372616195345
PET/MRI48832108018

Number of Participants With Positive or Negative Results in PET, MRI or PET/MRI for Prostate Cancer Compared to Histological Findings

PET positive lesions were measured on its own and evaluated as malignant just as hypointense lesions on MRI. In PET/MRI analysis, MRI suspect lesions without FEC uptake were considered not to be malignant. PET positive lesions in central periurethral zone with inhomogenous signal intensity and sharp edges on MRI images were also considered to be benign. PET positive lesions in the peripheral zone without a hypointense correlate on MRI were considered to be malignant. At least 1 histological confirmed cancer lesion has to be detected by each of the 3 methods to be patient based true positive. (NCT00520546)
Timeframe: within < 2 weeks after PET/MRI

,,
Interventionparticipants (Number)
True PositiveFalse PositiveTrue NegativeFalse NegativeTotal TrueTotal False
[18F]Fluoroethylcholine Positron-Emission-Tomography (FEC-PET)36101362
Magnetic Resonance Imaging (MRI)2610112711
PositronEmissionTomography/MagneticResonanceImaging (PET/MRI)35012362

Reviews

6 reviews available for creatine and Cancer of Prostate

ArticleYear
The role of metabolic imaging in radiation therapy of prostate cancer.
    NMR in biomedicine, 2014, Volume: 27, Issue:1

    Topics: Aged; Biopsy; Creatine; Diagnostic Imaging; Humans; Ki-67 Antigen; Male; Metabolomics; Phosphorylcho

2014
Novel biomarker for prostate cancer diagnosis by MRS.
    Frontiers in bioscience (Landmark edition), 2014, 06-01, Volume: 19, Issue:7

    Topics: Biomarkers, Tumor; Choline; Citric Acid; Creatine; Humans; Inositol; Magnetic Resonance Spectroscopy

2014
Diffusion-weighted imaging with apparent diffusion coefficient mapping and spectroscopy in prostate cancer.
    Topics in magnetic resonance imaging : TMRI, 2008, Volume: 19, Issue:6

    Topics: Biomarkers, Tumor; Choline; Citrates; Contrast Media; Creatine; Diagnosis, Differential; Diffusion M

2008
Prostate MRI and 3D MR spectroscopy: how we do it.
    AJR. American journal of roentgenology, 2010, Volume: 194, Issue:6

    Topics: Choline; Citrates; Creatine; Diagnosis, Differential; Humans; Image Enhancement; Image Interpretatio

2010
[1H magnetic resonance spectroscopy of the prostate].
    Der Radiologe, 2003, Volume: 43, Issue:6

    Topics: Biopsy; Choline; Citrates; Creatine; Follow-Up Studies; Humans; Imaging, Three-Dimensional; Magnetic

2003
Proton MR spectroscopy of the prostate.
    European journal of radiology, 2007, Volume: 63, Issue:3

    Topics: Biopsy; Choline; Citric Acid; Creatine; Diagnosis, Differential; Humans; Imaging, Three-Dimensional;

2007

Trials

1 trial available for creatine and Cancer of Prostate

ArticleYear
Examining the effects of creatine supplementation in augmenting adaptations to resistance training in patients with prostate cancer undergoing androgen deprivation therapy: a randomised, double-blind, placebo-controlled trial.
    BMJ open, 2019, 09-20, Volume: 9, Issue:9

    Topics: Aged; Androgen Antagonists; Body Composition; Combined Modality Therapy; Creatine; Dietary Supplemen

2019

Other Studies

49 other studies available for creatine and Cancer of Prostate

ArticleYear
Cyclocreatine Suppresses Creatine Metabolism and Impairs Prostate Cancer Progression.
    Cancer research, 2022, 07-18, Volume: 82, Issue:14

    Topics: Animals; Creatine; Creatinine; Disease Models, Animal; Humans; Intracellular Signaling Peptides and

2022
Feasibility of clinical studies of chemical exchange saturation transfer magnetic resonance imaging of prostate cancer at 7 T.
    NMR in biomedicine, 2023, Volume: 36, Issue:10

    Topics: Aged; Amides; Amines; Creatine; Feasibility Studies; Humans; Magnetic Resonance Imaging; Male; Prost

2023
Characterization of prostate cancer with MR spectroscopic imaging and diffusion-weighted imaging at 3 Tesla.
    Magnetic resonance imaging, 2019, Volume: 55

    Topics: Adult; Aged; Area Under Curve; Biopsy; Choline; Creatine; Diffusion Magnetic Resonance Imaging; Huma

2019
MR spectroscopy of the prostate at 3T: measurements of relaxation times and quantification of prostate metabolites using water as an internal reference.
    Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2013, Dec-25, Volume: 12, Issue:4

    Topics: Adult; Aged; Biomarkers, Tumor; Body Water; Choline; Citric Acid; Creatine; Humans; Magnetic Resonan

2013
Multiparametric 3T MRI in the evaluation of intraglandular prostate cancer: correlation with histopathology.
    Journal of medical imaging and radiation oncology, 2014, Volume: 58, Issue:4

    Topics: Adult; Aged; Biomarkers, Tumor; Choline; Creatine; Humans; Image Interpretation, Computer-Assisted;

2014
Technical Note: evaluation of the uncertainties in (choline + creatine)/citrate ratios measured by proton MR spectroscopic imaging in patients suspicious for prostate cancer.
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2014, Volume: 186, Issue:7

    Topics: Adult; Aged; Algorithms; Biomarkers, Tumor; Choline; Citric Acid; Creatine; Humans; Magnetic Resonan

2014
Contribution of Histopathologic Tissue Composition to Quantitative MR Spectroscopy and Diffusion-weighted Imaging of the Prostate.
    Radiology, 2016, Volume: 278, Issue:3

    Topics: Biomarkers, Tumor; Choline; Citric Acid; Creatine; Diffusion Magnetic Resonance Imaging; Humans; Ima

2016
MR Spectroscopy in Prostate Cancer: New Algorithms to Optimize Metabolite Quantification.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Algorithms; Choline; Citric Acid; Creatine; Humans; Magnetic Resonance Spectroscopy; Male; Phantoms,

2016
Two-dimensional spectroscopic imaging for pretreatment evaluation of prostate cancer: comparison with the step-section histology after radical prostatectomy.
    Magnetic resonance imaging, 2009, Volume: 27, Issue:1

    Topics: Adult; Aged; Biopsy; Case-Control Studies; Choline; Citric Acid; Creatine; False Negative Reactions;

2009
Two-dimensional MR spectroscopy of healthy and cancerous prostates in vivo.
    Magma (New York, N.Y.), 2008, Volume: 21, Issue:6

    Topics: Choline; Creatine; Epithelial Cells; Humans; Image Enhancement; Magnetic Resonance Spectroscopy; Mal

2008
Regarding the focal treatment of prostate cancer: inference of the Gleason grade from magnetic resonance spectroscopic imaging.
    International journal of radiation oncology, biology, physics, 2009, May-01, Volume: 74, Issue:1

    Topics: Algorithms; Biopsy; Choline; Citric Acid; Creatine; Humans; Logistic Models; Magnetic Resonance Spec

2009
1H-MRSI of prostate cancer: the relationship between metabolite ratio and tumor proliferation.
    European journal of radiology, 2010, Volume: 73, Issue:2

    Topics: Aged; Aged, 80 and over; Algorithms; Biomarkers, Tumor; Choline; Citric Acid; Creatine; Diagnosis, C

2010
Reduced power magnetic resonance spectroscopic imaging of the prostate at 4.0 Tesla.
    Magnetic resonance in medicine, 2009, Volume: 61, Issue:2

    Topics: Adult; Biomarkers, Tumor; Choline; Citric Acid; Creatine; Electromagnetic Fields; Humans; Magnetic R

2009
Peripheral zone prostate cancer. Pre-treatment evaluation with MR and 3D ¹H MR spectroscopic imaging: correlation with pathologic findings.
    Abdominal imaging, 2010, Volume: 35, Issue:6

    Topics: Aged; Biopsy; Choline; Creatine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy

2010
Correlation of endorectal 2D JPRESS findings with pathological Gleason scores in prostate cancer patients.
    NMR in biomedicine, 2010, Volume: 23, Issue:3

    Topics: Aged; Choline; Citric Acid; Creatine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Pr

2010
3D MR-spectroscopic imaging assessment of metabolic activity in the prostate during the PSA "bounce" following 125iodine brachytherapy.
    International journal of radiation oncology, biology, physics, 2011, Feb-01, Volume: 79, Issue:2

    Topics: Brachytherapy; Choline; Citric Acid; Creatine; Humans; Iodine Radioisotopes; Magnetic Resonance Imag

2011
Tumor volume and metabolism of prostate cancer determined by proton magnetic resonance spectroscopic imaging at 3T without endorectal coil reveal potential clinical implications in the context of radiation oncology.
    International journal of radiation oncology, biology, physics, 2011, Jul-15, Volume: 80, Issue:4

    Topics: Aged; Biomarkers, Tumor; Choline; Citric Acid; Creatine; Humans; Magnetic Resonance Spectroscopy; Ma

2011
Detection of fully refocused polyamine spins in prostate cancer at 7 T.
    NMR in biomedicine, 2011, Volume: 24, Issue:3

    Topics: Biomarkers, Tumor; Choline; Citric Acid; Creatine; Humans; Magnetic Resonance Spectroscopy; Male; Po

2011
Quantitative (1) H MR spectroscopic imaging of the prostate gland using LCModel and a dedicated basis-set: correlation with histologic findings.
    Magnetic resonance in medicine, 2011, Volume: 65, Issue:2

    Topics: Adenocarcinoma; Choline; Citric Acid; Creatine; Humans; In Vitro Techniques; Magnetic Resonance Spec

2011
In vivo assessment of prostate cancer aggressiveness using magnetic resonance spectroscopic imaging at 3 T with an endorectal coil.
    European urology, 2011, Volume: 60, Issue:5

    Topics: Adult; Aged; Biomarkers, Tumor; Biopsy; Choline; Citric Acid; Creatine; Equipment Design; Humans; Ma

2011
A phase and frequency alignment protocol for 1H MRSI data of the prostate.
    NMR in biomedicine, 2012, Volume: 25, Issue:5

    Topics: Algorithms; Choline; Citric Acid; Computer Simulation; Creatine; Databases, Factual; Humans; Magneti

2012
Effect of gold marker seeds on magnetic resonance spectroscopy of the prostate.
    International journal of radiation oncology, biology, physics, 2012, May-01, Volume: 83, Issue:1

    Topics: Biomarkers; Choline; Citrates; Creatine; Fiducial Markers; Gold; Humans; Magnetic Resonance Spectros

2012
Compressive sensing could accelerate 1H MR metabolic imaging in the clinic.
    Radiology, 2012, Volume: 262, Issue:3

    Topics: Algorithms; Analysis of Variance; Aspartic Acid; Brain Neoplasms; Choline; Citric Acid; Creatine; Da

2012
Locally advanced prostate cancer: three-dimensional magnetic resonance spectroscopy to monitor prostate response to therapy.
    International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Choline; Combined Moda

2012
In-vivo metabolic characterization of healthy prostate and orthotopic prostate cancer in rats using proton magnetic resonance spectroscopy at 4.7 T.
    Acta radiologica (Stockholm, Sweden : 1987), 2013, Feb-01, Volume: 54, Issue:1

    Topics: Animals; Cell Line, Tumor; Choline; Creatine; Humans; Inositol; Magnetic Resonance Imaging; Magnetic

2013
Spatially matched in vivo and ex vivo MR metabolic profiles of prostate cancer -- investigation of a correlation with Gleason score.
    NMR in biomedicine, 2013, Volume: 26, Issue:5

    Topics: Aged; Aged, 80 and over; Choline; Citric Acid; Creatine; Humans; Magnetic Resonance Spectroscopy; Ma

2013
2D JPRESS of human prostates using an endorectal receiver coil.
    Magnetic resonance in medicine, 2002, Volume: 47, Issue:6

    Topics: Adult; Biomarkers, Tumor; Choline; Citric Acid; Creatine; Humans; Magnetic Resonance Spectroscopy; M

2002
Proton two-dimensional chemical shift imaging for evaluation of prostate cancer: external surface coil vs. endorectal surface coil.
    Journal of magnetic resonance imaging : JMRI, 2002, Volume: 16, Issue:6

    Topics: Adult; Aged; Choline; Citric Acid; Creatine; Humans; Magnetic Resonance Imaging; Magnetic Resonance

2002
Transition zone prostate cancer: metabolic characteristics at 1H MR spectroscopic imaging--initial results.
    Radiology, 2003, Volume: 229, Issue:1

    Topics: Choline; Citric Acid; Creatine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy;

2003
[REABSORPTION OF PHOSPHORUS IN THE RENAL TUBULES IN NONPARATHYROGENOUS DISEASES].
    Nordisk medicin, 1964, May-07, Volume: 71

    Topics: Adenoma; Bone Neoplasms; Breast Neoplasms; Creatine; Creatinine; Denmark; Diagnosis, Differential; H

1964
HORMONE EXCRETION PATTERNS IN BREAST AND PROSTATE CANCER ARE ABNORMAL.
    Science (New York, N.Y.), 1964, Aug-14, Volume: 145, Issue:3633

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Aged; Androsterone; Breast Neoplasms; Creatine; Creatinine

1964
UREA-CREATININE RATIO IN OBSTRUCTIVE UROPATHY AND RENAL HYPERTENSION.
    JAMA, 1964, Nov-23, Volume: 190

    Topics: Acute Kidney Injury; Blood; Blood Urea Nitrogen; Creatine; Creatinine; Humans; Hypertension, Renal;

1964
URINARY EXCRETION OF NEUTRAL 17-KETOSTEROIDS AND PREGNANEDIOL BY PATIENTS WITH PROSTATIC CANCER AND BENIGN PROSTATIC HYPERTROPHY.
    The Journal of urology, 1965, Volume: 93

    Topics: 17-Ketosteroids; Androsterone; Blood Glucose; Blood Urea Nitrogen; Creatine; Creatinine; Etiocholano

1965
Proton magnetic resonance spectroscopy with a body coil in the diagnosis of carcinoma prostate.
    Urological research, 2004, Volume: 32, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma; Choline; Citric Acid; Creatine; Diagnosis, Differential;

2004
Dynamic magnetic resonance tomography and proton magnetic resonance spectroscopy of prostate cancers in rats treated by radiotherapy.
    Investigative radiology, 2004, Volume: 39, Issue:1

    Topics: Animals; Antigens, CD34; Choline; Creatine; Disease Models, Animal; Immunohistochemistry; Magnetic R

2004
In vivo prostate magnetic resonance spectroscopic imaging using two-dimensional J-resolved PRESS at 3 T.
    Magnetic resonance in medicine, 2005, Volume: 53, Issue:5

    Topics: Choline; Citrates; Creatine; Humans; Magnetic Resonance Spectroscopy; Male; Phantoms, Imaging; Prost

2005
Prostate cancer: a comparative study of 11C-choline PET and MR imaging combined with proton MR spectroscopy.
    European journal of nuclear medicine and molecular imaging, 2005, Volume: 32, Issue:7

    Topics: Aged; Biopsy; Carbon Radioisotopes; Choline; Citrates; Creatine; Humans; Magnetic Resonance Spectros

2005
High-grade prostatic intraepithelial neoplasia in patients with prostate cancer: MR and MR spectroscopic imaging features--initial experience.
    Radiology, 2007, Volume: 242, Issue:2

    Topics: Aged; Cell Nucleus; Cell Nucleus Size; Choline; Citric Acid; Cohort Studies; Creatine; Humans; Image

2007
Combined morphological, [1H]-MR spectroscopic and contrast-enhanced imaging of human prostate cancer with a 3-Tesla scanner: preliminary experience.
    La Radiologia medica, 2008, Volume: 113, Issue:5

    Topics: Aged; Choline; Citric Acid; Contrast Media; Creatine; Gadolinium; Humans; Image Processing, Computer

2008
[Urinary hydroxyproline excretion as a marker of bone metastasis in prostatic cancer (II): Correlation between extent of metastatic lesions in whole body bone scintigraphy of patients with prostatic cancer and tumor markers in blood and urine].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1984, Volume: 75, Issue:1

    Topics: Aged; Alkaline Phosphatase; Bone and Bones; Bone Neoplasms; Creatine; Humans; Hydroxyproline; Male;

1984
In vitro proton magnetic resonance spectroscopy of four human prostate cancer cell lines.
    The Prostate, 1995, Volume: 26, Issue:5

    Topics: Androgens; Citrates; Citric Acid; Creatine; Humans; Magnetic Resonance Spectroscopy; Male; Perchlora

1995
Three-dimensional H-1 MR spectroscopic imaging of the in situ human prostate with high (0.24-0.7-cm3) spatial resolution.
    Radiology, 1996, Volume: 198, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Choline; Citrates; Citric Acid; Creatine; Diagnosis, Differential; Huma

1996
Prostate cancer: metabolic response to cryosurgery as detected with 3D H-1 MR spectroscopic imaging.
    Radiology, 1996, Volume: 200, Issue:2

    Topics: Aged; Choline; Citrates; Citric Acid; Creatine; Cryosurgery; Humans; Magnetic Resonance Imaging; Mag

1996
Cyclocreatine inhibits stimulated motility in tumor cells possessing creatine kinase.
    International journal of cancer, 1998, Sep-25, Volume: 78, Issue:1

    Topics: Antineoplastic Agents; Cell Movement; Chemotaxis; Cisplatin; Creatine; Creatine Kinase; Creatinine;

1998
In vivo proton magnetic resonance spectroscopy of diseased prostate: spectroscopic features of malignant versus benign pathology.
    Magnetic resonance imaging, 1999, Volume: 17, Issue:5

    Topics: Aged; Aged, 80 and over; Choline; Citric Acid; Creatine; Diagnosis, Differential; Humans; Inositol;

1999
[Spectroscopic imaging (1H-2D-CSI) of the prostate: sequence optimization and correlation with histopathological results].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2000, Volume: 172, Issue:7

    Topics: Aged; Choline; Citrates; Creatine; Diagnosis, Differential; Humans; Magnetic Resonance Spectroscopy;

2000
Differentiation of human prostate cancer from benign hypertrophy by in vitro 1H NMR.
    Magnetic resonance in medicine, 1992, Volume: 25, Issue:1

    Topics: Alanine; Citrates; Creatine; Glutamates; Glutamic Acid; Humans; In Vitro Techniques; Magnetic Resona

1992
Urinary hydroxyproline excretion in patients with cancer.
    Cancer, 1969, Volume: 24, Issue:2

    Topics: Alkaline Phosphatase; Bone Neoplasms; Breast Neoplasms; Calcium; Collagen; Creatine; Female; Humans;

1969
Serum levels of methacycline.
    Chemotherapy, 1966, Volume: 11, Issue:6

    Topics: Adult; Aged; Biological Assay; Blood Urea Nitrogen; Bronchopneumonia; Cachexia; Cerebrovascular Diso

1966