creatine and Brain Vascular Disorders studies

creatine and Brain Vascular Disorders

Research Excerpts

Excerpt	Relevance	Reference
"To our knowledge, this is the first study to assess the response to treatment of a MELAS strokelike episode and the first to show an increase in the lactate-creatine ratio in a brain region that was associated with a clinical abnormality, even though it appeared normal on magnetic resonance imaging."	3.70	Magnetic resonance spectroscopy: use in monitoring MELAS treatment. ( Kaplan, GP; Kingsley, PB; Lustbader, D; O'Shea, M; Pavlakis, SG; Stacpoole, PW, 1998)
"Effects of benidipine hydrochloride or triple therapy (hydralazine, reserpine, and hydrochlorothiazide) on renal cortical and medullary intrinsic antioxidant enzyme (AOE) activity were evaluated in stroke-prone spontaneously hypertensive rats (SHR-SP) as an animal model for human essential hypertension with cerebral stroke."	3.69	Effects of benidipine hydrochloride on antioxidant enzyme activity in stroke-prone spontaneous hypertensive rats (SHR-SP). ( Fukui, M; Shou, I; Takahashi, Y; Tomino, Y; Wang, LN, 1997)
"In this study, we used a global cerebral ischemia induced by four-vessel occlusion as an established animal model for ischemic stroke to investigate metabolic changes after 24 h reperfusion, when transitions occur due to the onset of delayed neuronal death."	1.48	NMR metabolomic study of blood plasma in ischemic and ischemically preconditioned rats: an increased level of ketone bodies and decreased content of glycolytic products 24 h after global cerebral ischemia. ( Baranovicova, E; Cierny, D; Grendar, M; Kalenska, D; Lehotsky, J; Tomascova, A, 2018)
"Choline levels were unchanged in the lesions."	1.29	Proton magnetic resonance spectroscopy and gadolinium-DTPA perfusion imaging of asymptomatic MRI white matter lesions. ( Barker, PB; Bryan, RN; Conturo, TE; Oppenheimer, SM; Preziosi, TJ; Soher, BJ, 1995)

Research

Studies (24)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (8.33)	18.7374
1990's	15 (62.50)	18.2507
2000's	4 (16.67)	29.6817
2010's	3 (12.50)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

2 (8.33)

18.7374

1990's

15 (62.50)

18.2507

2000's

4 (16.67)

29.6817

2010's

3 (12.50)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Baranovicova, E	1
Grendar, M	1
Kalenska, D	1
Tomascova, A	1
Cierny, D	1
Lehotsky, J	1
Niu, XQ	1
Zhao, XX	1
Li, BC	1
Gao, YJ	1
Xu, W	1
Fan, YD	1
Fu, GP	1
Wang, K	1
Pu, J	1
Wada, M	1
Nagasawa, H	1
Iseki, C	1
Takahashi, Y	2
Sato, H	1
Arawaka, S	1
Kawanami, T	1
Kurita, K	1
Daimon, M	1
Kato, T	1
Kantarci, K	2
Petersen, RC	2
Przybelski, SA	2
Weigand, SD	2
Shiung, MM	2
Whitwell, JL	2
Negash, S	2
Ivnik, RJ	1
Boeve, BF	2
Knopman, DS	2
Smith, GE	1
Jack, CR	2
O'Brien, PC	1
Coutinho, T	1
Turner, ST	1
Kullo, IJ	1
Mathews, VP	1
Barker, PB	2
Blackband, SJ	1
Chatham, JC	1
Bryan, RN	2
Blamire, AM	1
Graham, GD	1
Rothman, DL	1
Prichard, JW	1
Oppenheimer, SM	1
Conturo, TE	1
Soher, BJ	1
Preziosi, TJ	1
Kamada, K	1
Houkin, K	1
Hida, K	1
Matsuzawa, H	1
Iwasaki, Y	1
Abe, H	1
Nakada, T	1
Stockhammer, G	1
Felber, SR	1
Zelger, B	1
Sepp, N	1
Birbamer, GG	1
Fritsch, PO	1
Aichner, FT	1
Marshall, I	2
Wardlaw, J	1
Cannon, J	1
Slattery, J	1
Sellar, RJ	1
Shou, I	1
Wang, LN	1
Fukui, M	1
Tomino, Y	1
Wild, JM	1
Hirano, S	1
Ishiyama, Y	1
Matsuo, T	1
Imamura, T	1
Sakata, J	1
Kitamura, K	1
Koiwaya, Y	1
Eto, T	1
Pavlakis, SG	1
Kingsley, PB	1
Kaplan, GP	1
Stacpoole, PW	1
O'Shea, M	1
Lustbader, D	1
Lee, TH	1
Marcantonio, ER	1
Mangione, CM	1
Thomas, EJ	1
Polanczyk, CA	1
Cook, EF	1
Sugarbaker, DJ	1
Donaldson, MC	1
Poss, R	1
Ho, KK	1
Ludwig, LE	1
Pedan, A	1
Goldman, L	1
Chan, YL	1
Roebuck, DJ	1
Yuen, MP	1
Yeung, KW	1
Lau, KY	1
Li, CK	1
Chik, KW	1
Wang, Z	1
Bogdan, AR	1
Zimmerman, RA	1
Gusnard, DA	1
Leigh, JS	1
Ohene-Frempong, K	1
Gideon, P	1
Henriksen, O	1
Sperling, B	1
Christiansen, P	1
Olsen, TS	1
Jørgensen, HS	1
Arlien-Søborg, P	1
Xie, JX	1
Sasaki, S	1
Joossens, JV	1
Kesteloot, H	1
Fenstermacher, MJ	1
Narayana, PA	1
Telfer, N	1
Persoff, M	1
Pitton, JS	1
Roch, P	1

Studies

Baranovicova, E

Grendar, M

Kalenska, D

Tomascova, A

Cierny, D

Lehotsky, J

Niu, XQ

Zhao, XX

Li, BC

Gao, YJ

Xu, W

Fan, YD

Fu, GP

Wang, K

Pu, J

Wada, M

Nagasawa, H

Iseki, C

Takahashi, Y

Sato, H

Arawaka, S

Kawanami, T

Kurita, K

Daimon, M

Kato, T

Kantarci, K

Petersen, RC

Przybelski, SA

Weigand, SD

Shiung, MM

Whitwell, JL

Negash, S

Ivnik, RJ

Boeve, BF

Knopman, DS

Smith, GE

Jack, CR

O'Brien, PC

Coutinho, T

Turner, ST

Kullo, IJ

Mathews, VP

Barker, PB

Blackband, SJ

Chatham, JC

Bryan, RN

Blamire, AM

Graham, GD

Rothman, DL

Prichard, JW

Oppenheimer, SM

Conturo, TE

Soher, BJ

Preziosi, TJ

Kamada, K

Houkin, K

Hida, K

Matsuzawa, H

Iwasaki, Y

Abe, H

Nakada, T

Stockhammer, G

Felber, SR

Zelger, B

Sepp, N

Birbamer, GG

Fritsch, PO

Aichner, FT

Marshall, I

Wardlaw, J

Cannon, J

Slattery, J

Sellar, RJ

Shou, I

Wang, LN

Fukui, M

Tomino, Y

Wild, JM

Hirano, S

Ishiyama, Y

Matsuo, T

Imamura, T

Sakata, J

Kitamura, K

Koiwaya, Y

Eto, T

Pavlakis, SG

Kingsley, PB

Kaplan, GP

Stacpoole, PW

O'Shea, M

Lustbader, D

Lee, TH

Marcantonio, ER

Mangione, CM

Thomas, EJ

Polanczyk, CA

Cook, EF

Sugarbaker, DJ

Donaldson, MC

Poss, R

Ho, KK

Ludwig, LE

Pedan, A

Goldman, L

Chan, YL

Roebuck, DJ

Yuen, MP

Yeung, KW

Lau, KY

Li, CK

Chik, KW

Wang, Z

Bogdan, AR

Zimmerman, RA

Gusnard, DA

Leigh, JS

Ohene-Frempong, K

Gideon, P

Henriksen, O

Sperling, B

Christiansen, P

Olsen, TS

Jørgensen, HS

Arlien-Søborg, P

Xie, JX

Sasaki, S

Joossens, JV

Kesteloot, H

Fenstermacher, MJ

Narayana, PA

Telfer, N

Persoff, M

Pitton, JS

Roch, P

Clinical Trials (7)

Trial Overview

Trial	Enrollment	Study Type	Start Date	Status
MRI Biomarkers of Risk in Sedentary and Exercise Trained Humans[NCT02729428]	71 participants (Actual)	Observational	2016-04-30	Completed
Utility of Pulmonary Echography for Evaluation of Patients Undergoing Orthopedic Surgery for Femur Fracture[NCT04074876]	877 participants (Actual)	Observational	2019-12-01	Active, not recruiting
Assessment of the Feasibility of Ultrasound Guided Serratus Plane Block Associated With Sedation as Anesthetic Technique in Axillary Dissection[NCT03740815]	15 participants (Actual)	Interventional	2018-09-25	Completed
The Application of Goal-directed Therapy With the Combination of Stroke Volume Variation and Cardiac Index as the Primary Judgment in Non-severe Patients Underwent Gastrointestinal Tumor Surgery[NCT02841046]	50 participants (Actual)	Interventional	2016-07-27	Completed
Pulse Wave Velocity as a Predictor for Postoperative Cardiovascular Events[NCT03223441]	543 participants (Actual)	Observational	2015-06-30	Completed
MET: REevaluation for Perioperative cArdIac Risk (MET-REPAIR): a Prospective, Multi-centre Cohort Observational Study- Presepsin (sCD14-ST) for Perioperative Risk Prediction Nested Cohort Study[NCT03489486]	1,695 participants (Anticipated)	Observational	2018-06-15	Recruiting
MET: REevaluation for Perioperative cArdIac Risk (MET-REPAIR) Observational Multicentre Study[NCT03016936]	15,000 participants (Actual)	Observational	2017-08-01	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial

Phase

Enrollment

Study Type

Start Date

Status

MRI Biomarkers of Risk in Sedentary and Exercise Trained Humans[NCT02729428]

71 participants (Actual)

Observational

2016-04-30

Completed

Utility of Pulmonary Echography for Evaluation of Patients Undergoing Orthopedic Surgery for Femur Fracture[NCT04074876]

877 participants (Actual)

Observational

2019-12-01

Active, not recruiting

Assessment of the Feasibility of Ultrasound Guided Serratus Plane Block Associated With Sedation as Anesthetic Technique in Axillary Dissection[NCT03740815]

15 participants (Actual)

Interventional

2018-09-25

Completed

The Application of Goal-directed Therapy With the Combination of Stroke Volume Variation and Cardiac Index as the Primary Judgment in Non-severe Patients Underwent Gastrointestinal Tumor Surgery[NCT02841046]

50 participants (Actual)

Interventional

2016-07-27

Completed

Pulse Wave Velocity as a Predictor for Postoperative Cardiovascular Events[NCT03223441]

543 participants (Actual)

Observational

2015-06-30

Completed

MET: REevaluation for Perioperative cArdIac Risk (MET-REPAIR): a Prospective, Multi-centre Cohort Observational Study- Presepsin (sCD14-ST) for Perioperative Risk Prediction Nested Cohort Study[NCT03489486]

1,695 participants (Anticipated)

Observational

2018-06-15

Recruiting

MET: REevaluation for Perioperative cArdIac Risk (MET-REPAIR) Observational Multicentre Study[NCT03016936]

15,000 participants (Actual)

Observational

2017-08-01

Completed

[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Days Needed for Anal Exsufflation After Surgery

record the number of days needed for anal exsufflation in non-severe patients after gastrointestinal tumor surgery (NCT02841046)
Timeframe: up to 8 weeks

Intervention	days (Mean)
Group Cardiac Index	3.8
Group Stroke Volume Variation	2.7

Intervention

days (Mean)

Group Cardiac Index

3.8

Group Stroke Volume Variation

2.7

Other Studies

24 other studies available for creatine and Brain Vascular Disorders

Article	Year
NMR metabolomic study of blood plasma in ischemic and ischemically preconditioned rats: an increased level of ketone bodies and decreased content of glycolytic products 24 h after global cerebral ischemia. Journal of physiology and biochemistry, 2018, Volume: 74, Issue:3 Topics: Acetic Acid; Animals; Biomarkers; Blood Glucose; Brain Ischemia; Cerebrovascular Disorders; Creatine	2018
¹H-MRS before and after resuscitation following selective cerebral ultra-profound hypothermic blood flow occlusion in monkeys. Genetics and molecular research : GMR, 2015, Oct-19, Volume: 14, Issue:4 Topics: Animals; Aspartic Acid; Brain; Carotid Stenosis; Cerebrovascular Disorders; Choline; Circulatory Arr	2015
Cerebral small vessel disease and chronic kidney disease (CKD): results of a cross-sectional study in community-based Japanese elderly. Journal of the neurological sciences, 2008, Sep-15, Volume: 272, Issue:1-2 Topics: Aged; Albuminuria; Analysis of Variance; Cerebrovascular Disorders; Chronic Disease; Creatine; Cross	2008
Hippocampal volumes, proton magnetic resonance spectroscopy metabolites, and cerebrovascular disease in mild cognitive impairment subtypes. Archives of neurology, 2008, Volume: 65, Issue:12 Topics: Aged; Aged, 80 and over; Aspartic Acid; Case-Control Studies; Cerebrovascular Disorders; Chi-Square	2008
Risk of dementia in MCI: combined effect of cerebrovascular disease, volumetric MRI, and 1H MRS. Neurology, 2009, Apr-28, Volume: 72, Issue:17 Topics: Aged; Aged, 80 and over; Aspartic Acid; Atrophy; Biomarkers; Brain; Cerebrovascular Disorders; Cogni	2009
Aortic pulse wave velocity is associated with measures of subclinical target organ damage. JACC. Cardiovascular imaging, 2011, Volume: 4, Issue:7 Topics: Aged; Albuminuria; Ankle Brachial Index; Aorta; Biomarkers; Cerebrovascular Disorders; Coronary Arte	2011
Cerebral metabolites in patients with acute and subacute strokes: concentrations determined by quantitative proton MR spectroscopy. AJR. American journal of roentgenology, 1995, Volume: 165, Issue:3 Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain; Cerebrovascular Dis	1995
Proton spectroscopy of human stroke: assessment of transverse relaxation times and partial volume effects in single volume steam MRS. Magnetic resonance imaging, 1994, Volume: 12, Issue:8 Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain Chemistry; Cerebrovascular Disorders; Choline; Creatin	1994
Proton magnetic resonance spectroscopy and gadolinium-DTPA perfusion imaging of asymptomatic MRI white matter lesions. Magnetic resonance in medicine, 1995, Volume: 33, Issue:1 Topics: Adult; Aged; Aspartic Acid; Brain; Brain Chemistry; Brain Diseases; Cerebrovascular Circulation; Cer	1995
Localized proton spectroscopy of focal brain pathology in humans: significant effects of edema on spin-spin relaxation time. Magnetic resonance in medicine, 1994, Volume: 31, Issue:5 Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Brain; Brain Edema; Brain Ischemia; Brain Neoplasms; Cerebr	1994
Sneddon's syndrome: diagnosis by skin biopsy and MRI in 17 patients. Stroke, 1993, Volume: 24, Issue:5 Topics: Adolescent; Adult; Angiography; Arteries; Biopsy; Cerebral Infarction; Cerebrovascular Disorders; Cr	1993
Reproducibility of metabolite peak areas in 1H MRS of brain. Magnetic resonance imaging, 1996, Volume: 14, Issue:3 Topics: Adult; Analysis of Variance; Artifacts; Aspartic Acid; Brain; Brain Neoplasms; Cerebrovascular Disor	1996
Effects of benidipine hydrochloride on antioxidant enzyme activity in stroke-prone spontaneous hypertensive rats (SHR-SP). Journal of clinical laboratory analysis, 1997, Volume: 11, Issue:3 Topics: Animals; Antioxidants; Blood Pressure; Calcium Channel Blockers; Catalase; Cerebrovascular Disorders	1997
Normalisation of metabolite images in 1H NMR spectroscopic imaging. Magnetic resonance imaging, 1997, Volume: 15, Issue:9 Topics: Algorithms; Artifacts; Aspartic Acid; Brain; Cerebrovascular Disorders; Choline; Creatine; Fourier A	1997
Decrease in circulating and urine adrenomedullin concentrations in stroke-prone spontaneously hypertensive rats. Hypertension research : official journal of the Japanese Society of Hypertension, 1998, Volume: 21, Issue:1 Topics: Adrenomedullin; Age Factors; Albuminuria; Animals; Antihypertensive Agents; Blood Pressure; Body Wei	1998
Magnetic resonance spectroscopy: use in monitoring MELAS treatment. Archives of neurology, 1998, Volume: 55, Issue:6 Topics: Adult; Brain; Cerebrovascular Disorders; Creatine; Dichloroacetic Acid; Female; Humans; Lactic Acid;	1998
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation, 1999, Sep-07, Volume: 100, Issue:10 Topics: Aged; Cerebrovascular Disorders; Cohort Studies; Creatine; Female; Heart Diseases; Humans; Incidence	1999
Long-term cerebral metabolite changes on proton magnetic resonance spectroscopy in patients cured of acute lymphoblastic leukemia with previous intrathecal methotrexate and cranial irradiation prophylaxis. International journal of radiation oncology, biology, physics, 2001, Jul-01, Volume: 50, Issue:3 Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Aspartic Acid; Brain; Brain Infarction; Cerebrov	2001
Investigation of stroke in sickle cell disease by 1H nuclear magnetic resonance spectroscopy. Neuroradiology, 1992, Volume: 35, Issue:1 Topics: Adolescent; Adult; Anemia, Sickle Cell; Aspartic Acid; Atrophy; Brain; Brain Ischemia; Cerebral Infa	1992
Early time course of N-acetylaspartate, creatine and phosphocreatine, and compounds containing choline in the brain after acute stroke. A proton magnetic resonance spectroscopy study. Stroke, 1992, Volume: 23, Issue:11 Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Chemistry; Cerebrovascular Circu	1992
The relationship between urinary cations obtained from the INTERSALT study and cerebrovascular mortality. Journal of human hypertension, 1992, Volume: 6, Issue:1 Topics: Aged; Blood Pressure; Calcium; Cerebrovascular Disorders; Creatine; Electrolytes; Female; Humans; In	1992
Serial proton magnetic resonance spectroscopy of ischemic brain injury in humans. Investigative radiology, 1990, Volume: 25, Issue:9 Topics: Aged; Aspartic Acid; Brain; Cerebrovascular Disorders; Choline; Creatine; Female; Humans; Magnetic R	1990
The effect of tube feeding on the hydration of elderly patients. Journal of gerontology, 1965, Volume: 20, Issue:4 Topics: Aged; Anuria; Blood Urea Nitrogen; Cerebrovascular Disorders; Chemistry Techniques, Analytical; Coro	1965
Serum levels of methacycline. Chemotherapy, 1966, Volume: 11, Issue:6 Topics: Adult; Aged; Biological Assay; Blood Urea Nitrogen; Bronchopneumonia; Cachexia; Cerebrovascular Diso	1966

Article

Year

NMR metabolomic study of blood plasma in ischemic and ischemically preconditioned rats: an increased level of ketone bodies and decreased content of glycolytic products 24 h after global cerebral ischemia.

Journal of physiology and biochemistry, 2018, Volume: 74, Issue:3

Topics: Acetic Acid; Animals; Biomarkers; Blood Glucose; Brain Ischemia; Cerebrovascular Disorders; Creatine

2018

¹H-MRS before and after resuscitation following selective cerebral ultra-profound hypothermic blood flow occlusion in monkeys.

Genetics and molecular research : GMR, 2015, Oct-19, Volume: 14, Issue:4

Topics: Animals; Aspartic Acid; Brain; Carotid Stenosis; Cerebrovascular Disorders; Choline; Circulatory Arr

2015

Cerebral small vessel disease and chronic kidney disease (CKD): results of a cross-sectional study in community-based Japanese elderly.

Journal of the neurological sciences, 2008, Sep-15, Volume: 272, Issue:1-2

Topics: Aged; Albuminuria; Analysis of Variance; Cerebrovascular Disorders; Chronic Disease; Creatine; Cross

2008

Hippocampal volumes, proton magnetic resonance spectroscopy metabolites, and cerebrovascular disease in mild cognitive impairment subtypes.

Archives of neurology, 2008, Volume: 65, Issue:12

Topics: Aged; Aged, 80 and over; Aspartic Acid; Case-Control Studies; Cerebrovascular Disorders; Chi-Square

2008

Risk of dementia in MCI: combined effect of cerebrovascular disease, volumetric MRI, and 1H MRS.

Neurology, 2009, Apr-28, Volume: 72, Issue:17

Topics: Aged; Aged, 80 and over; Aspartic Acid; Atrophy; Biomarkers; Brain; Cerebrovascular Disorders; Cogni

2009

Aortic pulse wave velocity is associated with measures of subclinical target organ damage.

JACC. Cardiovascular imaging, 2011, Volume: 4, Issue:7

Topics: Aged; Albuminuria; Ankle Brachial Index; Aorta; Biomarkers; Cerebrovascular Disorders; Coronary Arte

2011

Cerebral metabolites in patients with acute and subacute strokes: concentrations determined by quantitative proton MR spectroscopy.

AJR. American journal of roentgenology, 1995, Volume: 165, Issue:3

Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain; Cerebrovascular Dis

1995

Proton spectroscopy of human stroke: assessment of transverse relaxation times and partial volume effects in single volume steam MRS.

Magnetic resonance imaging, 1994, Volume: 12, Issue:8

Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain Chemistry; Cerebrovascular Disorders; Choline; Creatin

1994

Proton magnetic resonance spectroscopy and gadolinium-DTPA perfusion imaging of asymptomatic MRI white matter lesions.

Magnetic resonance in medicine, 1995, Volume: 33, Issue:1

Topics: Adult; Aged; Aspartic Acid; Brain; Brain Chemistry; Brain Diseases; Cerebrovascular Circulation; Cer

1995

Localized proton spectroscopy of focal brain pathology in humans: significant effects of edema on spin-spin relaxation time.

Magnetic resonance in medicine, 1994, Volume: 31, Issue:5

Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Brain; Brain Edema; Brain Ischemia; Brain Neoplasms; Cerebr

1994

Sneddon's syndrome: diagnosis by skin biopsy and MRI in 17 patients.

Stroke, 1993, Volume: 24, Issue:5

Topics: Adolescent; Adult; Angiography; Arteries; Biopsy; Cerebral Infarction; Cerebrovascular Disorders; Cr

1993

Reproducibility of metabolite peak areas in 1H MRS of brain.

Magnetic resonance imaging, 1996, Volume: 14, Issue:3

Topics: Adult; Analysis of Variance; Artifacts; Aspartic Acid; Brain; Brain Neoplasms; Cerebrovascular Disor

1996

Effects of benidipine hydrochloride on antioxidant enzyme activity in stroke-prone spontaneous hypertensive rats (SHR-SP).

Journal of clinical laboratory analysis, 1997, Volume: 11, Issue:3

Topics: Animals; Antioxidants; Blood Pressure; Calcium Channel Blockers; Catalase; Cerebrovascular Disorders

1997

Normalisation of metabolite images in 1H NMR spectroscopic imaging.

Magnetic resonance imaging, 1997, Volume: 15, Issue:9

Topics: Algorithms; Artifacts; Aspartic Acid; Brain; Cerebrovascular Disorders; Choline; Creatine; Fourier A

1997

Decrease in circulating and urine adrenomedullin concentrations in stroke-prone spontaneously hypertensive rats.

Hypertension research : official journal of the Japanese Society of Hypertension, 1998, Volume: 21, Issue:1

Topics: Adrenomedullin; Age Factors; Albuminuria; Animals; Antihypertensive Agents; Blood Pressure; Body Wei

1998

Magnetic resonance spectroscopy: use in monitoring MELAS treatment.

Archives of neurology, 1998, Volume: 55, Issue:6

Topics: Adult; Brain; Cerebrovascular Disorders; Creatine; Dichloroacetic Acid; Female; Humans; Lactic Acid;

1998

Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery.