creatine has been researched along with Brain Edema in 28 studies
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Severe hyponatremia and hypoosmolality induced profound decreases in levels of brain electrolytes, amino acids (especially taurine), and creatine." | 7.67 | Adaptive decreases in amino acids (taurine in particular), creatine, and electrolytes prevent cerebral edema in chronically hyponatremic mice: rapid correction (experimental model of central pontine myelinolysis) causes dehydration and shrinkage of brain. ( Hauhart, RE; Nelson, JS; Thurston, JH, 1987) |
| "We hypothesized that creatine (Cr) supplementation would preserve energy metabolism and thus ameliorate the energy failure and the extent of brain edema seen after severe but transient cerebral hypoxia-ischemia (HI) in the neonatal rat model." | 3.71 | Neuroprotection of creatine supplementation in neonatal rats with transient cerebral hypoxia-ischemia. ( Adcock, KH; Loenneker, T; Martin, E; Nedelcu, J; Wagner, BP; Wallimann, T, 2002) |
| " Severe hyponatremia and hypoosmolality induced profound decreases in levels of brain electrolytes, amino acids (especially taurine), and creatine." | 3.67 | Adaptive decreases in amino acids (taurine in particular), creatine, and electrolytes prevent cerebral edema in chronically hyponatremic mice: rapid correction (experimental model of central pontine myelinolysis) causes dehydration and shrinkage of brain. ( Hauhart, RE; Nelson, JS; Thurston, JH, 1987) |
| "Brain alterations such as hepatic encephalopathy or brain edema are usually associated with liver failure." | 2.50 | Magnetic resonance of the brain in chronic and acute liver failure. ( Chavarria, L; Cordoba, J, 2014) |
| "Brain edema was maximal on MR imaging 3 h after poisoning." | 1.42 | Early brain magnetic resonance imaging can predict short and long-term outcomes after organophosphate poisoning in a rat model. ( Cohen, Y; Eisenkraft, A; Kadar, T; Kassirer, M; Milk, N; Rosman, Y; Shiyovich, A; Shrot, S; Tauber, M, 2015) |
| "Cerebral edema is present in patients with MHE." | 1.36 | Effect of surgical portosystemic shunt on prevalence of minimal hepatic encephalopathy in children with extrahepatic portal venous obstruction: assessment by magnetic resonance imaging and psychometry. ( Gupta, RK; Lal, R; Saraswat, VA; Srivastava, A; Thomas, MA; Yachha, SK; Yadav, SK, 2010) |
| "Subclinical cerebral edema occurs in many, if not most, children with diabetic ketoacidosis (DKA) and may be an indicator of subtle brain injury." | 1.34 | Cerebral proton magnetic resonance spectroscopy in children with diabetic ketoacidosis. ( Barnes, PD; Buonocore, MH; DiCarlo, J; Glaser, NS; Kuppermann, N; Marcin, JP; McCarthy, T; Neely, EK; Wootton-Gorges, SL, 2007) |
| "PEHO syndrome is a rare symptom complex of severe progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy." | 1.33 | Serial MR imaging, diffusion tensor imaging, and MR spectroscopic findings in a child with progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy (PEHO) syndrome. ( Boltshauser, E; Huisman, TA; Klein, A; Straube, T; Werner, B, 2006) |
| "Choline peak area was increased in tumor, creatine and N-acetyl aspartate were decreased in edema and tumor compared with unaffected brain tissue." | 1.31 | 1H chemical shift imaging characterization of human brain tumor and edema. ( Oudkerk, M; Sijens, PE, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.14) | 18.7374 |
| 1990's | 5 (17.86) | 18.2507 |
| 2000's | 11 (39.29) | 29.6817 |
| 2010's | 10 (35.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chavarria, L | 1 |
| Cordoba, J | 1 |
| Parra, NA | 1 |
| Maudsley, AA | 1 |
| Gupta, RK | 3 |
| Ishkanian, F | 1 |
| Huang, K | 1 |
| Walker, GR | 1 |
| Padgett, K | 1 |
| Roy, B | 1 |
| Panoff, J | 1 |
| Markoe, A | 1 |
| Stoyanova, R | 1 |
| Shrot, S | 1 |
| Tauber, M | 1 |
| Shiyovich, A | 1 |
| Milk, N | 1 |
| Rosman, Y | 1 |
| Eisenkraft, A | 1 |
| Kadar, T | 1 |
| Kassirer, M | 1 |
| Cohen, Y | 1 |
| Tian, R | 1 |
| Han, L | 1 |
| Hou, Z | 1 |
| Hao, S | 1 |
| Mao, X | 1 |
| Zhu, Z | 1 |
| Tao, X | 1 |
| Zhang, Q | 1 |
| Liu, B | 1 |
| Oeltzschner, G | 1 |
| Butz, M | 1 |
| Wickrath, F | 1 |
| Wittsack, HJ | 1 |
| Schnitzler, A | 1 |
| Yoon, KJ | 1 |
| Lee, YT | 1 |
| Chae, SW | 1 |
| Park, CR | 1 |
| Kim, DY | 1 |
| Schubert, GA | 1 |
| Poli, S | 1 |
| Schilling, L | 1 |
| Heiland, S | 1 |
| Thomé, C | 1 |
| Lim, SY | 1 |
| Wesley Thevathasan, A | 1 |
| Gonzales, M | 1 |
| Mitchell, PJ | 1 |
| Evans, A | 1 |
| Lescot, T | 1 |
| Fulla-Oller, L | 2 |
| Po, C | 1 |
| Chen, XR | 1 |
| Puybasset, L | 1 |
| Gillet, B | 1 |
| Plotkine, M | 1 |
| Meric, P | 1 |
| Marchand-Leroux, C | 1 |
| Wootton-Gorges, SL | 2 |
| Buonocore, MH | 2 |
| Caltagirone, RA | 1 |
| Kuppermann, N | 2 |
| Glaser, NS | 2 |
| Srivastava, A | 1 |
| Yadav, SK | 1 |
| Lal, R | 1 |
| Yachha, SK | 1 |
| Thomas, MA | 1 |
| Saraswat, VA | 1 |
| Righi, V | 1 |
| Tugnoli, V | 1 |
| Mucci, A | 1 |
| Bacci, A | 1 |
| Bonora, S | 1 |
| Schenetti, L | 1 |
| Sijens, PE | 1 |
| Oudkerk, M | 1 |
| Rumpel, H | 1 |
| Lim, WE | 1 |
| Chang, HM | 1 |
| Chan, LL | 1 |
| Ho, GL | 1 |
| Wong, MC | 1 |
| Tan, KP | 1 |
| Adcock, KH | 1 |
| Nedelcu, J | 1 |
| Loenneker, T | 1 |
| Martin, E | 1 |
| Wallimann, T | 1 |
| Wagner, BP | 1 |
| Briellmann, RS | 1 |
| Wellard, RM | 1 |
| Jackson, GD | 1 |
| Huisman, TA | 1 |
| Klein, A | 1 |
| Werner, B | 1 |
| Straube, T | 1 |
| Boltshauser, E | 1 |
| Marcin, JP | 1 |
| Barnes, PD | 1 |
| Neely, EK | 1 |
| DiCarlo, J | 1 |
| McCarthy, T | 1 |
| Go, KG | 1 |
| Kamman, RL | 1 |
| Mooyaart, EL | 1 |
| Heesters, MA | 1 |
| Pruim, J | 1 |
| Vaalburg, W | 1 |
| Paans, AM | 1 |
| Kamada, K | 1 |
| Houkin, K | 1 |
| Hida, K | 1 |
| Matsuzawa, H | 1 |
| Iwasaki, Y | 1 |
| Abe, H | 1 |
| Nakada, T | 1 |
| Kimura, H | 1 |
| Grossman, RI | 1 |
| Lenkinski, RE | 1 |
| Gonzalez-Scarano, F | 1 |
| Chumas, P | 1 |
| Condon, B | 1 |
| Oluoch-Olunya, D | 1 |
| Griffiths, S | 1 |
| Hadley, D | 1 |
| Teasdale, G | 1 |
| Sengar, AR | 1 |
| Dhanuka, AK | 1 |
| Roy, R | 1 |
| Das, K | 1 |
| Son, BC | 1 |
| Park, CK | 1 |
| Choi, BG | 1 |
| Kim, EN | 1 |
| Choe, BY | 1 |
| Lee, KS | 1 |
| Kim, MC | 1 |
| Kang, JK | 1 |
| Schuhmann, MU | 1 |
| Stiller, D | 1 |
| Thomas, S | 1 |
| Brinker, T | 1 |
| Samii, M | 1 |
| Fatouros, PP | 1 |
| Heath, DL | 1 |
| Beaumont, A | 1 |
| Corwin, FD | 1 |
| Signoretti, S | 1 |
| al-Samsam, RH | 1 |
| Alessandri, B | 1 |
| Lazzarino, P | 1 |
| Vagnozzi, R | 1 |
| Tavazzi, B | 1 |
| Bullock, R | 1 |
| Marmarou, A | 1 |
| Shimoda, M | 1 |
| Yamada, S | 1 |
| Matsumae, M | 1 |
| Yamamoto, I | 1 |
| Tsugane, R | 1 |
| Sato, O | 1 |
| Thurston, JH | 1 |
| Hauhart, RE | 1 |
| Nelson, JS | 1 |
2 reviews available for creatine and Brain Edema
| Article | Year |
|---|---|
Magnetic resonance of the brain in chronic and acute liver failure.
Topics: Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Brain Edema; Choline; Creatine; Glutamic Acid; Gl | 2014 |
Seizure-associated abnormalities in epilepsy: evidence from MR imaging.
Topics: Adult; Aspartic Acid; Atrophy; Brain; Brain Diseases; Brain Edema; Choline; Creatine; Diffusion Magn | 2005 |
26 other studies available for creatine and Brain Edema
| Article | Year |
|---|---|
Volumetric spectroscopic imaging of glioblastoma multiforme radiation treatment volumes.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Edema; Brain Mapping; Brain Neoplasms; Choline; Creatine; F | 2014 |
Early brain magnetic resonance imaging can predict short and long-term outcomes after organophosphate poisoning in a rat model.
Topics: Animals; Aspartic Acid; Atropine; Behavior, Animal; Brain; Brain Edema; Choline; Cholinesterase Reac | 2015 |
Neuroprotective efficacy of decompressive craniectomy after controlled cortical impact injury in rats: An MRI study.
Topics: Animals; Aspartic Acid; Brain; Brain Edema; Brain Injuries; Choline; Creatine; Decompressive Craniec | 2015 |
Covert hepatic encephalopathy: elevated total glutathione and absence of brain water content changes.
Topics: Aged; Ammonia; Brain; Brain Edema; Creatine; Female; Glutathione; Hepatic Encephalopathy; Humans; Ma | 2016 |
Effects of anodal transcranial direct current stimulation (tDCS) on behavioral and spatial memory during the early stage of traumatic brain injury in the rats.
Topics: Analysis of Variance; Animals; Aspartic Acid; Brain Edema; Brain Injuries, Traumatic; Brain-Derived | 2016 |
Hypothermia reduces cytotoxic edema and metabolic alterations during the acute phase of massive SAH: a diffusion-weighted imaging and spectroscopy study in rats.
Topics: Acute Disease; Animals; Aspartic Acid; Body Temperature; Brain; Brain Edema; Cerebral Cortex; Creati | 2008 |
Vasogenic oedema with no mass lesion.
Topics: Aged; Brain; Brain Edema; C-Reactive Protein; Cerebral Amyloid Angiopathy; Cerebral Arteries; Cerebr | 2008 |
Temporal and regional changes after focal traumatic brain injury.
Topics: Animals; Aspartic Acid; Brain; Brain Edema; Brain Injuries; Brain Mapping; Cerebral Cortex; Choline; | 2010 |
Progressive decrease in N-acetylaspartate/Creatine ratio in a teenager with type 1 diabetes and repeated episodes of ketoacidosis without clinically apparent cerebral edema: Evidence for permanent brain injury.
Topics: Adolescent; Aspartic Acid; Basal Ganglia; Blood Glucose; Brain; Brain Damage, Chronic; Brain Edema; | 2010 |
Effect of surgical portosystemic shunt on prevalence of minimal hepatic encephalopathy in children with extrahepatic portal venous obstruction: assessment by magnetic resonance imaging and psychometry.
Topics: Adolescent; Ammonia; Brain Edema; Child; Creatine; Cross-Sectional Studies; Female; Glutamine; Hepat | 2010 |
MRS study of meningeal hemangiopericytoma and edema: a comparison with meningothelial meningioma.
Topics: 3-Hydroxybutyric Acid; Alanine; Aspartic Acid; Brain Edema; Choline; Creatine; Glutamic Acid; Glutat | 2012 |
1H chemical shift imaging characterization of human brain tumor and edema.
Topics: Aspartic Acid; Brain Edema; Brain Neoplasms; Choline; Creatine; Humans; Hydrogen; Magnetic Resonance | 2002 |
Is myo-inositol a measure of glial swelling after stroke? A magnetic resonance study.
Topics: Aged; Aged, 80 and over; Brain Edema; Creatine; Female; Humans; Inositol; Magnetic Resonance Imaging | 2003 |
Neuroprotection of creatine supplementation in neonatal rats with transient cerebral hypoxia-ischemia.
Topics: Animals; Animals, Newborn; Brain Edema; Creatine; Hypoxia-Ischemia, Brain; Magnetic Resonance Imagin | 2002 |
Serial MR imaging, diffusion tensor imaging, and MR spectroscopic findings in a child with progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy (PEHO) syndrome.
Topics: Aspartic Acid; Atrophy; Brain Diseases; Brain Edema; Cerebellum; Child; Choline; Creatine; Diffusion | 2006 |
Cerebral proton magnetic resonance spectroscopy in children with diabetic ketoacidosis.
Topics: Adolescent; Aspartic Acid; Brain; Brain Edema; Child; Choline; Consciousness Disorders; Creatine; Di | 2007 |
Localised proton spectroscopy and spectroscopic imaging in cerebral gliomas, with comparison to positron emission tomography.
Topics: Aspartic Acid; Brain; Brain Chemistry; Brain Edema; Carbon Radioisotopes; Creatine; Deoxyglucose; Fl | 1995 |
Localized proton spectroscopy of focal brain pathology in humans: significant effects of edema on spin-spin relaxation time.
Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Brain; Brain Edema; Brain Ischemia; Brain Neoplasms; Cerebr | 1994 |
Proton MR spectroscopy and magnetization transfer ratio in multiple sclerosis: correlative findings of active versus irreversible plaque disease.
Topics: Adult; Aspartic Acid; Brain; Brain Diseases; Brain Edema; Choline; Chronic Disease; Creatine; Demyel | 1996 |
Early changes in peritumorous oedema and contralateral white matter after dexamethasone: a study using proton magnetic resonance spectroscopy.
Topics: Antineoplastic Agents, Hormonal; Aspartic Acid; Brain; Brain Edema; Brain Neoplasms; Choline; Creati | 1997 |
MR imaging, MR angiography, and MR spectroscopy of the brain in eclampsia.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Edema; Brain Ischemia; Cerebral Arteries; Choline; Cr | 1997 |
Metabolic changes in pericontusional oedematous areas in mild head injury evaluated by 1H MRS.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Concussion; Brain Edema; Brain Ischemia; Creati | 2000 |
1H-MR spectroscopic monitoring of posttraumatic metabolism following controlled cortical impact injury: pilot study.
Topics: Animals; Aspartic Acid; Brain Concussion; Brain Edema; Cerebral Cortex; Choline; Creatine; Energy Me | 2000 |
Comparison of NAA measures by MRS and HPLC.
Topics: Animals; Aspartic Acid; Brain Concussion; Brain Edema; Chromatography, High Pressure Liquid; Creatin | 2000 |
[Renal protection in acute neurosurgical diseases--effect of a low dose dopamine with reference to acute renal failure and hypernatremia in patients with dehydration].
Topics: Acute Kidney Injury; Adolescent; Adult; Blood Urea Nitrogen; Brain; Brain Edema; Creatine; Dehydrati | 1988 |
Adaptive decreases in amino acids (taurine in particular), creatine, and electrolytes prevent cerebral edema in chronically hyponatremic mice: rapid correction (experimental model of central pontine myelinolysis) causes dehydration and shrinkage of brain.
Topics: Acclimatization; Adenine Nucleotides; Amino Acids; Animals; Brain; Brain Edema; Creatine; Demyelinat | 1987 |