Page last updated: 2024-10-17

creatine and Brain Disorders

creatine has been researched along with Brain Disorders in 80 studies

Research Excerpts

ExcerptRelevanceReference
"Choline is elevated in the basal ganglia and prefrontal cortical regions, suggesting regionally increased membrane turnover or glial activation in schizophrenia."9.41Meta-analytic evidence of elevated choline, reduced N-acetylaspartate, and normal creatine in schizophrenia and their moderation by measurement quality, echo time, and medication status. ( Maddock, RJ; Smucny, J; Yang, YS; Zhang, H, 2023)
"We planned to include trials comparing creatine given to women in pregnancy for fetal neuroprotection (regardless of the route, timing, dose, or duration of administration) with placebo, no treatment, or with an alternative agent aimed at providing fetal neuroprotection."8.90Creatine for women in pregnancy for neuroprotection of the fetus. ( Bain, E; Crowther, CA; Dickinson, H; Middleton, P; Walker, DW; Wilkinson, D, 2014)
" We observed mild cerebral and cerebellar atrophy and infarct at bilateral posterior putamen and insular cortex localization on conventional images and elevated choline/creatine ratios and abnormal peak at 3."7.74Neuroimaging findings in hyperargininemia. ( Akinci, A; Alkan, A; Firat, AK; Güngör, S; Tabel, Y, 2008)
"Choline is elevated in the basal ganglia and prefrontal cortical regions, suggesting regionally increased membrane turnover or glial activation in schizophrenia."5.41Meta-analytic evidence of elevated choline, reduced N-acetylaspartate, and normal creatine in schizophrenia and their moderation by measurement quality, echo time, and medication status. ( Maddock, RJ; Smucny, J; Yang, YS; Zhang, H, 2023)
"We planned to include trials comparing creatine given to women in pregnancy for fetal neuroprotection (regardless of the route, timing, dose, or duration of administration) with placebo, no treatment, or with an alternative agent aimed at providing fetal neuroprotection."4.90Creatine for women in pregnancy for neuroprotection of the fetus. ( Bain, E; Crowther, CA; Dickinson, H; Middleton, P; Walker, DW; Wilkinson, D, 2014)
"Higher triglyceride and lower HDL levels statistically account for the association between BMI and myo-inositol, pointing toward a potentially critical role for dyslipidemia in the development of cerebral neurochemical alterations in obesity."3.79Dyslipidemia links obesity to early cerebral neurochemical alterations. ( Gonzales, MM; Haley, AP; Tanaka, H; Tarumi, T, 2013)
" We observed mild cerebral and cerebellar atrophy and infarct at bilateral posterior putamen and insular cortex localization on conventional images and elevated choline/creatine ratios and abnormal peak at 3."3.74Neuroimaging findings in hyperargininemia. ( Akinci, A; Alkan, A; Firat, AK; Güngör, S; Tabel, Y, 2008)
"Eight patients with advanced breast cancer were entered into a prospective, longitudinal trial that included examination by MR imaging and proton MR spectroscopy before chemotherapy and through 12 months after treatment with carmustine, cyclophosphamide, and cisplatin, combined with autologous hematopoietic progenitor cell support (AHPCS)."3.70White matter disease induced by high-dose chemotherapy: longitudinal study with MR imaging and proton spectroscopy. ( Brown, MS; Cagnoni, PJ; Jones, RB; Sheeder, JL; Simon, JH; Stears, JC; Stemmer, SM, 1998)
" All high-grade gliomas (n = 37) showed high choline and low or absent N-acetyl-L-aspartate and creatine along with lipid and/or lactate, whereas low-grade gliomas (n = 23) were characterized by low N-acetyl-aspartate and creatine and high choline and presence of only lactate."3.69Characterization of intracranial mass lesions with in vivo proton MR spectroscopy. ( Chhabra, DK; Gupta, RK; Jain, VK; Pandey, R; Poptani, H; Roy, R, 1995)
"(a) Hamartomas showed higher N-acetyl aspartate/creatine, creatine/choline, and N-acetyl aspartate/choline ratios than gliomas."3.69Proton MR spectroscopy in patients with neurofibromatosis type 1: evaluation of hamartomas and clinical correlation. ( Castillo, M; Green, C; Greenwood, R; Kwock, L; Schiro, S; Smith, K; Wilson, D, 1995)
"Most cases of the narcoleptic syndrome are considered to be idiopathic because no structural lesion is detectable, although some cases of secondary narcolepsy are known to be associated with no structural brainstem lesions."2.69Proton spectroscopy in the narcoleptic syndrome. Is there evidence of a brainstem lesion? ( Ellis, CM; Lemmens, G; Parkes, JD; Simmons, A; Williams, SC, 1998)
"Lipopolysaccharide (LPS)-induced encephalopathy induces neuroinflammation."1.51Anti-inflammatory agent, OKN-007, reverses long-term neuroinflammatory responses in a rat encephalopathy model as assessed by multi-parametric MRI: implications for aging-associated neuroinflammation. ( Gulej, R; Lawrence, B; McKenzie, T; Morton, KA; Saunders, D; Smith, N; Towner, RA, 2019)
"The histological diagnosis was anaplastic oligodendroglioma (WHO grade III)."1.37[Usefulness of quantitative H-MR spectroscopy for the differentiation between radiation necrosis and recurrence of anaplastic oligodendroglioma]. ( Akutsu, H; Anno, I; Isobe, T; Masumoto, T; Matsumura, A; Nakai, K; Shiigai, M; Takano, S; Yamamoto, T, 2011)
"Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL) is a recently described disorder with autosomal recessive mode of inheritance."1.35Leukoencephalopathy with brain stem and spinal cord involvement and high lactate: a genetically proven case with distinct MRI findings. ( Baskan, O; Gunal, DI; Isak, B; Koseoglu, M; Ozsahin, S; Scheper, GC; Uluc, K; van der Knaap, MS; Yildirim, KA, 2008)
"PEHO syndrome is a rare symptom complex of severe progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy."1.33Serial MR imaging, diffusion tensor imaging, and MR spectroscopic findings in a child with progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy (PEHO) syndrome. ( Boltshauser, E; Huisman, TA; Klein, A; Straube, T; Werner, B, 2006)
"Most of the brain tumors were characterized by strongly reduced total N-acetylaspartyl compounds and marked increases of myo-inositol and choline-containing compounds, consistent with a lack of neuroaxonal tissue and a proliferation of glial cells."1.31Quantitative proton magnetic resonance spectroscopy of focal brain lesions. ( Dechent, P; Frahm, J; Hanefeld, F; Herms, J; Markakis, E; Maxton, C; Wilken, B, 2000)
"This elevation is unrelated to hepatic encephalopathy or a history of intravenous drug abuse, and suggests that a biological process underlies the extrahepatic symptoms in chronic HCV infection."1.31Evidence for a cerebral effect of the hepatitis C virus. ( Allsop, JM; Forton, DM; Foster, GR; Main, J; Taylor-Robinson, SD; Thomas, HC, 2001)
"Two cases of reversible posterior leukoencephalopathy syndrome were examined with proton MR spectroscopic imaging."1.31Diffuse metabolic abnormalities in reversible posterior leukoencephalopathy syndrome. ( Barker, PB; Beauchamp, NJ; Eichler, FS; Wang, P; Wityk, RJ, 2002)
"The study included 12 patients with progressive supranuclear palsy, 10 with Parkinson's disease, nine with corticobasal degeneration and 11 age-matched normal control subjects."1.30Proton magnetic resonance spectroscopic imaging in progressive supranuclear palsy, Parkinson's disease and corticobasal degeneration. ( Bertolino, A; Bonavita, S; Hallett, M; Litvan, I; Lundbom, N; Patronas, NJ; Tedeschi, G, 1997)
"Late juvenile neuronal ceroid lipofuscinosis (NCL) is a lysosomal neurodegenerative disorder caused by the accumulation of lipopigment in neurons."1.30MR imaging and localized proton MR spectroscopy in late infantile neuronal ceroid lipofuscinosis. ( Grodd, W; Klose, U; Nägele, T; Schwab, A; Seeger, U; Seitz, D, 1998)
"Choline levels were unchanged in the lesions."1.29Proton magnetic resonance spectroscopy and gadolinium-DTPA perfusion imaging of asymptomatic MRI white matter lesions. ( Barker, PB; Bryan, RN; Conturo, TE; Oppenheimer, SM; Preziosi, TJ; Soher, BJ, 1995)
"Four grades of demyelination and three grades of cerebral atrophy were distinguished by magnetic resonance imaging criteria."1.281H and 31P magnetic resonance spectroscopy of the brain in degenerative cerebral disorders. ( den Hollander, JA; Luyten, PR; Nauta, JJ; Valk, J; van der Grond, J; van der Knaap, MS, 1992)

Research

Studies (80)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.25)18.7374
1990's23 (28.75)18.2507
2000's37 (46.25)29.6817
2010's15 (18.75)24.3611
2020's4 (5.00)2.80

Authors

AuthorsStudies
Mueller, C1
Baird, JF1
Motl, RW1
Matveeva, MV1
Samoilova, YG1
Kudlay, DA1
Yang, YS1
Smucny, J1
Zhang, H1
Maddock, RJ1
Towner, RA1
Saunders, D1
Smith, N1
Gulej, R1
McKenzie, T1
Lawrence, B1
Morton, KA1
Wang, AP1
Suryavanshi, T1
Marcucci, M1
Fong, C1
Whitton, AC1
Reddy, KKV1
Haley, AP1
Gonzales, MM1
Tarumi, T1
Tanaka, H1
Bladowska, J1
Zimny, A1
Knysz, B1
Małyszczak, K1
Kołtowska, A1
Szewczyk, P1
Gąsiorowski, J1
Furdal, M1
Sąsiadek, MJ1
Hansen, MB1
Kondziella, D1
Danielsen, ER1
Larsen, VA1
Jansen, EC1
Hyldegaard, O1
Nakagami, R1
Yamaguchi, M1
Ezawa, K1
Kimura, S1
Hamamichi, S1
Sekine, N1
Furukawa, A1
Niitsu, M1
Fujii, H1
Dickinson, H1
Bain, E1
Wilkinson, D1
Middleton, P1
Crowther, CA1
Walker, DW1
Mørkrid, L1
Rowe, AD1
Elgstoen, KB1
Olesen, JH1
Ruijter, G1
Hall, PL1
Tortorelli, S1
Schulze, A1
Kyriakopoulou, L1
Wamelink, MM1
van de Kamp, JM1
Salomons, GS1
Rinaldo, P1
Chen, WS1
Li, JJ1
Hong, L1
Xing, ZB1
Wang, F1
Li, CQ1
Rackayova, V1
Cudalbu, C1
Pouwels, PJW1
Braissant, O1
Uluc, K1
Baskan, O1
Yildirim, KA1
Ozsahin, S1
Koseoglu, M1
Isak, B1
Scheper, GC1
Gunal, DI1
van der Knaap, MS2
Wood, PB1
Ledbetter, CR1
Glabus, MF1
Broadwell, LK1
Patterson, JC1
Josey, L1
Al Sayyari, A1
Buckley, R1
Coulthard, A1
de Araújo Filho, GM1
Lin, K1
Lin, J1
Peruchi, MM1
Caboclo, LO1
Guaranha, MS1
Guilhoto, LM1
Carrete, H1
Yacubian, EM1
Sohn, SY1
Ko, YJ1
Hong, JM1
Kim, SH1
Kim, HS1
Kim, JH1
Chi, JG1
Moon, SY1
Girard, N1
Isobe, T1
Akutsu, H1
Yamamoto, T1
Shiigai, M1
Masumoto, T1
Nakai, K1
Takano, S1
Anno, I1
Matsumura, A1
Prado, PT1
Escorsi-Rosset, S1
Cervi, MC1
Santos, AC1
Gualano, B1
Roschel, H1
Lancha, AH1
Brightbill, CE1
Rawson, ES1
Wang, Y1
Jia, Y1
Xu, G1
Ling, X1
Liu, S1
Huang, L1
Gelal, F1
Callí, C1
Apaydín, M1
Erdem, G1
Eichler, FS2
Itoh, R1
Barker, PB5
Mori, S1
Garrett, ES1
van Zijl, PC2
Moser, HW2
Raymond, GV1
Melhem, ER1
Smith, JK1
Londono, A1
Castillo, M2
Kwock, L2
Baik, HM1
Choe, BY1
Son, BC1
Kim, MC1
Kim, EN1
Lee, HK1
Suh, TS1
Firbank, MJ1
Minett, T1
O'Brien, JT1
Nagae-Poetscher, LM1
Bibat, G1
Philippart, M1
Rosemberg, S1
Fatemi, A1
Lacerda, MT1
Costa, MO1
Kok, F1
Costa Leite, C1
Horská, A1
Naidu, S1
Castellino, G1
Govoni, M1
Padovan, M1
Colamussi, P1
Borrelli, M1
Trotta, F1
Chang, L2
Ernst, T2
Speck, O1
Grob, CS1
Briellmann, RS1
Wellard, RM1
Jackson, GD1
De Stefano, N1
Bartolozzi, ML1
Guidi, L1
Stromillo, ML1
Federico, A1
Groeschel, S1
Brockmann, K2
Dechent, P3
Wilichowski, E1
Frahm, J3
Hanefeld, F2
Koudijs, SM1
van der Grond, J2
Hoogendoorn, ML1
Hulshoff Pol, HE1
Schnack, HG1
Witkamp, TD1
Gooskens, RH1
van Nieuwenhuizen, O1
Braun, KP1
Huisman, TA1
Klein, A1
Werner, B1
Straube, T1
Boltshauser, E1
Porto, L1
Hattingen, E1
Pilatus, U1
Kieslich, M1
Yan, B1
Schwabe, D1
Zanella, FE1
Lanfermann, H1
Mason, GF1
Di Costanzo, A2
Trojsi, F1
Tosetti, M2
Schirmer, T1
Lechner, SM1
Popolizio, T2
Scarabino, T2
Giannatempo, GM1
d'Alesio, V1
Esposito, F1
Di Salle, F1
Bertolino, A2
Maggialetti, A1
Salvolini, U1
Qiu, SJ1
Zhang, XL1
Zhang, Y1
Jiang, M1
Taylor, MJ1
Schweinsburg, BC1
Alhassoon, OM1
Gongvatana, A1
Brown, GG1
Young-Casey, C1
Letendre, SL1
Grant, I1
Kayabas, U1
Alkan, A2
Firat, AK2
Karakas, HM1
Bayindir, Y1
Yetkin, F1
Nitkunan, A1
Charlton, RA1
McIntyre, DJ1
Barrick, TR1
Howe, FA2
Markus, HS1
Güngör, S1
Akinci, A1
Tabel, Y1
Dreha-Kulaczewski, SF1
Finsterbusch, J1
Gärtner, J1
Hanefeld, FA1
Dezortova, M1
Hajek, M2
Emad, Y1
Ragab, Y1
Zeinhom, F1
El-Khouly, G1
Abou-Zeid, A1
Rasker, JJ1
Constans, JM1
Meyerhoff, DJ1
Gerson, J1
MacKay, S1
Norman, D1
Fein, G1
Weiner, MW2
Miller, BL1
McBride, D1
Cornford, M1
Oropilla, G1
Buchthal, S1
Chiang, F1
Aronow, H1
Beck, CK1
Poptani, H1
Gupta, RK1
Roy, R1
Pandey, R1
Jain, VK1
Chhabra, DK1
Tedeschi, G2
Schiffmann, R1
Barton, NW1
Shih, HH1
Gospe, SM1
Brady, RO1
Alger, JR1
Di Chiro, G1
Davie, CA1
Wenning, GK1
Barker, GJ1
Tofts, PS1
Kendall, BE1
Quinn, N1
McDonald, WI1
Marsden, CD1
Miller, DH1
Oppenheimer, SM1
Bryan, RN1
Conturo, TE1
Soher, BJ1
Preziosi, TJ1
Green, C1
Smith, K1
Wilson, D1
Schiro, S1
Greenwood, R1
Erecińska, M1
Nelson, D1
Kruse, B1
Duyn, JH1
Moonen, CT1
Hejcmanová, L1
Prádný, J1
Kimura, H1
Grossman, RI2
Lenkinski, RE3
Gonzalez-Scarano, F1
Jarvik, JG1
Saykin, AJ1
Jaans, A1
Frank, I1
Tourbah, A1
Stievenart, JL1
Iba-Zizen, MT1
Zannoli, G1
Lyon-Caen, O1
Cabanis, EA1
Jackson, EF1
Meyers, CA1
Litvan, I1
Bonavita, S1
Lundbom, N1
Patronas, NJ1
Hallett, M1
Burtscher, IM2
Ståhlberg, F1
Holtås, S2
Ellis, CM1
Simmons, A1
Lemmens, G1
Williams, SC1
Parkes, JD1
Brown, MS1
Stemmer, SM1
Simon, JH1
Stears, JC1
Jones, RB1
Cagnoni, PJ1
Sheeder, JL1
Cecil, KM1
Hills, EC1
Sandel, ME1
Smith, DH1
McIntosh, TK1
Mannon, LJ1
Sinson, GP1
Bagley, LJ1
Laubenberger, J1
Bayer, S1
Thiel, T1
Hennig, J1
Langer, M1
Seitz, D1
Grodd, W1
Schwab, A1
Seeger, U1
Klose, U1
Nägele, T1
Rudkin, TM1
Arnold, DL1
Kaplanski, G1
Cacoub, P1
Farnarier, C1
Marin, V1
Grégoire, R1
Gatel, A1
Durand, JM1
Harlé, JR1
Bongrand, P1
Piette, JC1
Wilken, B1
Herms, J1
Maxton, C1
Markakis, E1
Axford, JS1
Heron, C1
Griffiths, JR1
Schuff, N1
Ezekiel, F1
Gamst, AC1
Amend, DL1
Capizzano, AA1
Maudsley, AA1
Forton, DM1
Allsop, JM1
Main, J1
Foster, GR1
Thomas, HC1
Taylor-Robinson, SD1
Kimura, T1
Sako, K1
Gotoh, T1
Tanaka, K1
Tanaka, T1
Wang, P1
Wityk, RJ1
Beauchamp, NJ1
Luyten, PR1
den Hollander, JA1
Nauta, JJ1
Valk, J1
Mouzet, MT1
Balsan, S1
Royer, P1

Reviews

13 reviews available for creatine and Brain Disorders

ArticleYear
Meta-analytic evidence of elevated choline, reduced N-acetylaspartate, and normal creatine in schizophrenia and their moderation by measurement quality, echo time, and medication status.
    NeuroImage. Clinical, 2023, Volume: 39

    Topics: Aspartic Acid; Brain Diseases; Choline; Creatine; Humans; Magnetic Resonance Spectroscopy; Schizophr

2023
Creatine for women in pregnancy for neuroprotection of the fetus.
    The Cochrane database of systematic reviews, 2014, Dec-19, Issue:12

    Topics: Brain Diseases; Creatine; Female; Fetal Diseases; Humans; Neuroprotective Agents; Pregnancy

2014
Diagnostic Value of Magnetic Resonance Spectroscopy in Radiation Encephalopathy Induced by Radiotherapy for Patients with Nasopharyngeal Carcinoma: A Meta-Analysis.
    BioMed research international, 2016, Volume: 2016

    Topics: Aspartic Acid; Brain Diseases; Carcinoma; Choline; Creatine; Humans; Magnetic Resonance Spectroscopy

2016
Creatine in the central nervous system: From magnetic resonance spectroscopy to creatine deficiencies.
    Analytical biochemistry, 2017, 07-15, Volume: 529

    Topics: Animals; Brain; Brain Diseases; Creatine; Energy Metabolism; Humans; Magnetic Resonance Imaging; Mag

2017
[Magnetic resonance spectroscopy for cerebral imaging].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2010, Volume: 17, Issue:6

    Topics: Apoptosis; Aspartic Acid; Asphyxia Neonatorum; Biomarkers, Tumor; Brain; Brain Diseases; Brain Disea

2010
In sickness and in health: the widespread application of creatine supplementation.
    Amino acids, 2012, Volume: 43, Issue:2

    Topics: Animals; Brain Diseases; Creatine; Dietary Supplements; Humans; Kidney; Musculoskeletal Diseases; Pe

2012
Seizure-associated abnormalities in epilepsy: evidence from MR imaging.
    Epilepsia, 2005, Volume: 46, Issue:5

    Topics: Adult; Aspartic Acid; Atrophy; Brain; Brain Diseases; Brain Edema; Choline; Creatine; Diffusion Magn

2005
Magnetic resonance spectroscopy as a measure of brain damage in multiple sclerosis.
    Journal of the neurological sciences, 2005, Jun-15, Volume: 233, Issue:1-2

    Topics: Aspartic Acid; Axons; Brain Diseases; Creatine; Disability Evaluation; Humans; Magnetic Resonance Im

2005
Proton MR spectroscopy of the brain at 3 T: an update.
    European radiology, 2007, Volume: 17, Issue:7

    Topics: Artifacts; Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Cerebral Cortex; Choline; Creatine

2007
(1)H MR spectroscopy in pediatrics.
    European journal of radiology, 2008, Volume: 67, Issue:2

    Topics: Aspartic Acid; Brain; Brain Chemistry; Brain Diseases; Child; Child, Preschool; Choline; Creatine; G

2008
Introduction to hippocampal spectroscopy.
    Neuroimaging clinics of North America, 1997, Volume: 7, Issue:1

    Topics: Aspartic Acid; Brain Diseases; Choline; Creatine; Hippocampus; Humans; Hydrogen; Image Enhancement;

1997
Proton magnetic resonance spectroscopy for the diagnosis and management of cerebral disorders.
    Archives of neurology, 1999, Volume: 56, Issue:8

    Topics: Aspartic Acid; Brain Diseases; Creatine; Humans; Magnetic Resonance Spectroscopy; Neurons; Protons

1999
Proton MR spectroscopy in clinical routine.
    Journal of magnetic resonance imaging : JMRI, 2001, Volume: 13, Issue:4

    Topics: Aspartic Acid; Brain Diseases; Choline; Creatine; Humans; Lactic Acid; Magnetic Resonance Spectrosco

2001

Trials

2 trials available for creatine and Brain Disorders

ArticleYear
Changes in DWI and MRS associated with white matter hyperintensities in elderly subjects.
    Neurology, 2003, Oct-14, Volume: 61, Issue:7

    Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Diseases; Choline; Creatine; Cross-Sectional St

2003
Proton spectroscopy in the narcoleptic syndrome. Is there evidence of a brainstem lesion?
    Neurology, 1998, Volume: 50, Issue:2 Suppl 1

    Topics: Adolescent; Adult; Aspartic Acid; Brain Diseases; Creatine; Female; Humans; Magnetic Resonance Spect

1998

Other Studies

65 other studies available for creatine and Brain Disorders

ArticleYear
Whole-Brain Metabolic Abnormalities Are Associated With Mobility in Older Adults With Multiple Sclerosis.
    Neurorehabilitation and neural repair, 2022, Volume: 36, Issue:4-5

    Topics: Aged; Aspartic Acid; Brain; Brain Diseases; Choline; Creatine; Humans; Inositol; Magnetic Resonance

2022
[Blood pressure variability and brain neuroimaging in patients with type 2 diabetes].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2022, Volume: 122, Issue:5

    Topics: Blood Pressure; Brain; Brain Diseases; Choline; Creatine; Diabetes Mellitus, Type 2; Humans; Neuroim

2022
Anti-inflammatory agent, OKN-007, reverses long-term neuroinflammatory responses in a rat encephalopathy model as assessed by multi-parametric MRI: implications for aging-associated neuroinflammation.
    GeroScience, 2019, Volume: 41, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Aspartic Acid; Benzenesulfonates; Brain Diseases; Cerebral Cortex

2019
Radiation Necrosis Following Stereotactic Radiosurgery for Trigeminal Neuralgia.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2020, Volume: 47, Issue:3

    Topics: Aged, 80 and over; Aspartic Acid; Brain Diseases; Brain Neoplasms; Choline; Creatine; Diagnostic Err

2020
Dyslipidemia links obesity to early cerebral neurochemical alterations.
    Obesity (Silver Spring, Md.), 2013, Volume: 21, Issue:10

    Topics: Adult; Aspartic Acid; Blood Glucose; Blood Pressure; Body Mass Index; Brain; Brain Diseases; Cholest

2013
Evaluation of early cerebral metabolic, perfusion and microstructural changes in HCV-positive patients: a pilot study.
    Journal of hepatology, 2013, Volume: 59, Issue:4

    Topics: Adult; Aspartic Acid; Blood Volume; Brain; Brain Diseases; Case-Control Studies; Cerebrovascular Cir

2013
Cerebral proton magnetic resonance spectroscopy demonstrates reversibility of N-acetylaspartate/creatine in gray matter after delayed encephalopathy due to carbon monoxide intoxication: a case report.
    Journal of medical case reports, 2014, Jun-19, Volume: 8

    Topics: Adult; Aspartic Acid; Brain; Brain Diseases; Carbon Monoxide Poisoning; Creatine; Female; Humans; Ma

2014
Recovery correction technique for NMR spectroscopy of perchloric acid extracts using DL-valine-2,3-d2: validation and application to 5-fluorouracil-induced brain damage.
    Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2014, Volume: 13, Issue:3

    Topics: Animals; Brain; Brain Diseases; Creatine; Fluorouracil; Magnetic Resonance Spectroscopy; Perchlorate

2014
Continuous age- and sex-adjusted reference intervals of urinary markers for cerebral creatine deficiency syndromes: a novel approach to the definition of reference intervals.
    Clinical chemistry, 2015, Volume: 61, Issue:5

    Topics: Age Factors; Biomarkers; Brain Diseases; Creatine; Female; Humans; Male; Models, Biological; Referen

2015
Leukoencephalopathy with brain stem and spinal cord involvement and high lactate: a genetically proven case with distinct MRI findings.
    Journal of the neurological sciences, 2008, Oct-15, Volume: 273, Issue:1-2

    Topics: Adult; Aspartate-tRNA Ligase; Aspartic Acid; Brain Diseases; Brain Stem; Creatine; Humans; Lactic Ac

2008
Hippocampal metabolite abnormalities in fibromyalgia: correlation with clinical features.
    The journal of pain, 2009, Volume: 10, Issue:1

    Topics: Adult; Aspartic Acid; Brain Diseases; Creatine; Female; Fibromyalgia; Hippocampus; Humans; Magnetic

2009
Usefulness of susceptibility-weighted imaging for voxel placement in MR spectroscopy.
    AJNR. American journal of neuroradiology, 2009, Volume: 30, Issue:4

    Topics: Artifacts; Aspartic Acid; Brain Diseases; Choline; Creatine; Electromagnetic Fields; Gadolinium; Hum

2009
Are personality traits of juvenile myoclonic epilepsy related to frontal lobe dysfunctions? A proton MRS study.
    Epilepsia, 2009, Volume: 50, Issue:5

    Topics: Adolescent; Adult; Aspartic Acid; Brain Diseases; Creatine; Female; Frontal Lobe; Glutamic Acid; Glu

2009
A case of pigmentary orthochromatic leukodystrophy with findings of proton MR spectroscopy and serial brain MRIs.
    Journal of the neurological sciences, 2010, Aug-15, Volume: 295, Issue:1-2

    Topics: Adult; Antigens, CD; Aspartic Acid; Brain; Brain Diseases; Brain Mapping; Creatine; Demyelinating Di

2010
[Usefulness of quantitative H-MR spectroscopy for the differentiation between radiation necrosis and recurrence of anaplastic oligodendroglioma].
    No shinkei geka. Neurological surgery, 2011, Volume: 39, Issue:5

    Topics: Adult; Aspartic Acid; Brain Diseases; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; F

2011
Image evaluation of HIV encephalopathy: a multimodal approach using quantitative MR techniques.
    Neuroradiology, 2011, Volume: 53, Issue:11

    Topics: Brain; Brain Diseases; Child; Child, Preschool; Choline; Creatine; Female; HIV Infections; Humans; M

2011
Frontal white matter biochemical abnormalities in first-episode, treatment-naive patients with major depressive disorder: a proton magnetic resonance spectroscopy study.
    Journal of affective disorders, 2012, Volume: 136, Issue:3

    Topics: Adolescent; Adult; Aspartic Acid; Brain Chemistry; Brain Diseases; Choline; Creatine; Depressive Dis

2012
van der Knaap's leukoencephalopathy: report of five new cases with emphasis on diffusion-weighted MRI findings.
    Neuroradiology, 2002, Volume: 44, Issue:7

    Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Brain Diseases; Child, Preschool; Choline; Creatine; C

2002
Proton MR spectroscopic and diffusion tensor brain MR imaging in X-linked adrenoleukodystrophy: initial experience.
    Radiology, 2002, Volume: 225, Issue:1

    Topics: Adolescent; Adrenoleukodystrophy; Adult; Aspartic Acid; Brain; Brain Chemistry; Brain Diseases; Chil

2002
Proton magnetic resonance spectroscopy of brain-stem lesions.
    Neuroradiology, 2002, Volume: 44, Issue:10

    Topics: Aspartic Acid; Brain; Brain Chemistry; Brain Diseases; Brain Stem; Brain Stem Neoplasms; Choline; Cr

2002
Feasibility of proton chemical shift imaging with a stereotactic headframe.
    Magnetic resonance imaging, 2003, Volume: 21, Issue:1

    Topics: Adult; Biopsy, Needle; Brain; Brain Diseases; Choline; Creatine; Feasibility Studies; Female; Humans

2003
Leukoencephalopathy, cerebral calcifications, and cysts: new observations.
    Neurology, 2004, Apr-13, Volume: 62, Issue:7

    Topics: Adolescent; Aspartic Acid; Brain; Brain Diseases; Calcinosis; Central Nervous System Cysts; Child; C

2004
Proton magnetic resonance spectroscopy may predict future brain lesions in SLE patients: a functional multi-imaging approach and follow up.
    Annals of the rheumatic diseases, 2005, Volume: 64, Issue:7

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Chemistry; Brain Diseases; Choline; Creatine; Female;

2005
Additive effects of HIV and chronic methamphetamine use on brain metabolite abnormalities.
    The American journal of psychiatry, 2005, Volume: 162, Issue:2

    Topics: Adult; Amphetamine-Related Disorders; Aspartic Acid; Basal Ganglia; Brain; Brain Diseases; Choline;

2005
Magnetic resonance imaging and proton magnetic resonance spectroscopy of megalencephaly and dilated Virchow-Robin spaces.
    Pediatric neurology, 2006, Volume: 34, Issue:1

    Topics: Aspartic Acid; Brain Diseases; Child; Child, Preschool; Choline; Creatine; Dilatation, Pathologic; D

2006
MRI, volumetry, 1H spectroscopy, and cerebropetal blood flowmetry in childhood idiopathic anatomic megalencephaly.
    Journal of magnetic resonance imaging : JMRI, 2006, Volume: 24, Issue:2

    Topics: Aspartic Acid; Blood Flow Velocity; Brain; Brain Diseases; Case-Control Studies; Cerebrovascular Cir

2006
Serial MR imaging, diffusion tensor imaging, and MR spectroscopic findings in a child with progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy (PEHO) syndrome.
    AJNR. American journal of neuroradiology, 2006, Volume: 27, Issue:7

    Topics: Aspartic Acid; Atrophy; Brain Diseases; Brain Edema; Cerebellum; Child; Choline; Creatine; Diffusion

2006
Proton magnetic resonance spectroscopy in childhood brainstem lesions.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2007, Volume: 23, Issue:3

    Topics: Adolescent; Amino Acids; Aspartic Acid; Brain Chemistry; Brain Diseases; Brain Stem; Brain Stem Neop

2007
Get sober; stay sober.
    Brain : a journal of neurology, 2007, Volume: 130, Issue:Pt 1

    Topics: Alcoholism; Aspartic Acid; Brain; Brain Diseases; Choline; Creatine; Humans; Magnetic Resonance Spec

2007
3.0-T functional brain imaging: a 5-year experience.
    La Radiologia medica, 2007, Volume: 112, Issue:1

    Topics: Artifacts; Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Cerebral Arteries; Cerebral Cortex

2007
Proton magnetic resonance spectroscopy for radiation encephalopathy induced by radiotherapy for nasopharyngeal carcinoma.
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2007, Volume: 27, Issue:3

    Topics: Adult; Aged; Aspartic Acid; Brain Diseases; Choline; Creatine; Female; Humans; Magnetic Resonance Sp

2007
Effects of human immunodeficiency virus and methamphetamine on cerebral metabolites measured with magnetic resonance spectroscopy.
    Journal of neurovirology, 2007, Volume: 13, Issue:2

    Topics: Adult; Aspartic Acid; Basal Ganglia; Brain; Brain Diseases; CD4 Lymphocyte Count; Central Nervous Sy

2007
Magnetic resonance spectroscopy features of normal-appearing white matter in patients with acute brucellosis.
    European journal of radiology, 2008, Volume: 65, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aspartic Acid; Brain Diseases; Brucellosis; Case-Control Studies;

2008
Diffusion tensor imaging and MR spectroscopy in hypertension and presumed cerebral small vessel disease.
    Magnetic resonance in medicine, 2008, Volume: 59, Issue:3

    Topics: Aged; Aspartic Acid; Brain Diseases; Brain Ischemia; Case-Control Studies; Cerebrovascular Circulati

2008
Neuroimaging findings in hyperargininemia.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2008, Volume: 18, Issue:4

    Topics: Arginine; Aspartic Acid; Atrophy; Basal Ganglia Cerebrovascular Disease; Brain Diseases; Cerebellum;

2008
Early reduction of total N-acetyl-aspartate-compounds in patients with classical vanishing white matter disease. A long-term follow-up MRS study.
    Pediatric research, 2008, Volume: 63, Issue:4

    Topics: Adolescent; Adult; Aspartic Acid; Axons; Brain Diseases; Cerebrum; Child; Child, Preschool; Creatine

2008
Hippocampus dysfunction may explain symptoms of fibromyalgia syndrome. A study with single-voxel magnetic resonance spectroscopy.
    The Journal of rheumatology, 2008, Volume: 35, Issue:7

    Topics: Adult; Aspartic Acid; Brain Diseases; Case-Control Studies; Choline; Creatine; Female; Fibromyalgia;

2008
H-1 MR spectroscopic imaging of white matter signal hyperintensities: Alzheimer disease and ischemic vascular dementia.
    Radiology, 1995, Volume: 197, Issue:2

    Topics: Aged; Alzheimer Disease; Aspartic Acid; Brain; Brain Diseases; Brain Ischemia; Case-Control Studies;

1995
Brain lesions in patients with AIDS: H-1 MR spectroscopy.
    Radiology, 1995, Volume: 197, Issue:2

    Topics: Abscess; Adult; AIDS Dementia Complex; Aspartic Acid; Brain Diseases; Brain Neoplasms; Choline; Crea

1995
Characterization of intracranial mass lesions with in vivo proton MR spectroscopy.
    AJNR. American journal of neuroradiology, 1995, Volume: 16, Issue:8

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Child; Choline; Crea

1995
Proton magnetic resonance spectroscopic imaging in childhood ataxia with diffuse central nervous system hypomyelination.
    Neurology, 1995, Volume: 45, Issue:8

    Topics: Aspartic Acid; Ataxia; Brain; Brain Diseases; Child, Preschool; Choline; Creatine; Female; Gaucher D

1995
Differentiation of multiple system atrophy from idiopathic Parkinson's disease using proton magnetic resonance spectroscopy.
    Annals of neurology, 1995, Volume: 37, Issue:2

    Topics: Adult; Aged; Aspartic Acid; Atrophy; Basal Ganglia; Brain Diseases; Choline; Creatine; Diagnosis, Di

1995
Proton magnetic resonance spectroscopy and gadolinium-DTPA perfusion imaging of asymptomatic MRI white matter lesions.
    Magnetic resonance in medicine, 1995, Volume: 33, Issue:1

    Topics: Adult; Aged; Aspartic Acid; Brain; Brain Chemistry; Brain Diseases; Cerebrovascular Circulation; Cer

1995
Proton MR spectroscopy in patients with neurofibromatosis type 1: evaluation of hamartomas and clinical correlation.
    AJNR. American journal of neuroradiology, 1995, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Aspartic Acid; Astrocytoma; Brain; Brain Diseases; Brain Neoplasms; Cerebellar Di

1995
Effects of 3-nitropropionic acid on synaptosomal energy and transmitter metabolism: relevance to neurodegenerative brain diseases.
    Journal of neurochemistry, 1994, Volume: 63, Issue:3

    Topics: Adenosine Triphosphate; Animals; Brain Diseases; Cell Death; Creatine; Energy Metabolism; gamma-Amin

1994
Multislice proton magnetic resonance spectroscopic imaging in X-linked adrenoleukodystrophy.
    Annals of neurology, 1994, Volume: 36, Issue:4

    Topics: Adolescent; Adrenoleukodystrophy; Adult; Aged; Aspartic Acid; Brain Diseases; Child; Child, Preschoo

1994
Proton in vivo spectroscopy of patients with hyperphenylalaninaemia.
    Neuropediatrics, 1993, Volume: 24, Issue:2

    Topics: Adult; Aspartic Acid; Biopterins; Brain; Brain Chemistry; Brain Diseases; Child; Choline; Creatine;

1993
Proton MR spectroscopy and magnetization transfer ratio in multiple sclerosis: correlative findings of active versus irreversible plaque disease.
    AJNR. American journal of neuroradiology, 1996, Volume: 17, Issue:8

    Topics: Adult; Aspartic Acid; Brain; Brain Diseases; Brain Edema; Choline; Chronic Disease; Creatine; Demyel

1996
Proton spectroscopy in asymptomatic HIV-infected adults: initial results in a prospective cohort study.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1996, Nov-01, Volume: 13, Issue:3

    Topics: Adult; Amino Acids; Brain; Brain Diseases; CD4 Lymphocyte Count; Choline; Creatine; Female; HIV Infe

1996
In vivo localized NMR proton spectroscopy of normal appearing white matter in patients with multiple sclerosis.
    Journal of neuroradiology = Journal de neuroradiologie, 1996, Volume: 23, Issue:2

    Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Brain Diseases; Choline; Clinical Trials as Topic

1996
Proton magnetic resonance spectroscopic imaging in progressive supranuclear palsy, Parkinson's disease and corticobasal degeneration.
    Brain : a journal of neurology, 1997, Volume: 120 ( Pt 9)

    Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Diseases; Choline; Creatine; Female; Humans; Ma

1997
Proton (1H) MR spectroscopy for routine diagnostic evaluation of brain lesions.
    Acta radiologica (Stockholm, Sweden : 1987), 1997, Volume: 38, Issue:6

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Diseases; Brain Neo

1997
White matter disease induced by high-dose chemotherapy: longitudinal study with MR imaging and proton spectroscopy.
    AJNR. American journal of neuroradiology, 1998, Volume: 19, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Brain; Brain Diseases; B

1998
Proton magnetic resonance spectroscopy for detection of axonal injury in the splenium of the corpus callosum of brain-injured patients.
    Journal of neurosurgery, 1998, Volume: 88, Issue:5

    Topics: Acceleration; Accidents, Traffic; Adult; Aged; Aspartic Acid; Axons; Brain Concussion; Brain Disease

1998
[Clinical uses of proton magnetic resonance spectroscopy of the brain].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1998, Volume: 168, Issue:6

    Topics: AIDS Dementia Complex; Alzheimer Disease; Animals; Aspartic Acid; Brain; Brain Diseases; Brain Disea

1998
MR imaging and localized proton MR spectroscopy in late infantile neuronal ceroid lipofuscinosis.
    AJNR. American journal of neuroradiology, 1998, Volume: 19, Issue:7

    Topics: Aspartic Acid; Brain; Brain Diseases; Case-Control Studies; Cerebellum; Cerebral Ventricles; Child;

1998
Increased soluble vascular cell adhesion molecule 1 concentrations in patients with primary or systemic lupus erythematosus-related antiphospholipid syndrome: correlations with the severity of thrombosis.
    Arthritis and rheumatism, 2000, Volume: 43, Issue:1

    Topics: Adult; Aged; Brain Diseases; Creatine; E-Selectin; Female; Humans; Intercellular Adhesion Molecule-1

2000
Quantitative proton magnetic resonance spectroscopy of focal brain lesions.
    Pediatric neurology, 2000, Volume: 23, Issue:1

    Topics: Adolescent; Aspartic Acid; Biomarkers, Tumor; Brain; Brain Abscess; Brain Diseases; Brain Neoplasms;

2000
Sensitivity of quantitative (1)H magnetic resonance spectroscopy of the brain in detecting early neuronal damage in systemic lupus erythematosus.
    Annals of the rheumatic diseases, 2001, Volume: 60, Issue:2

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Diseases; Case-Control Studies; Choline; Creatine; Fem

2001
Region and tissue differences of metabolites in normally aged brain using multislice 1H magnetic resonance spectroscopic imaging.
    Magnetic resonance in medicine, 2001, Volume: 45, Issue:5

    Topics: Aged; Aged, 80 and over; Aging; Analysis of Variance; Aspartic Acid; Brain; Brain Diseases; Choline;

2001
Evidence for a cerebral effect of the hepatitis C virus.
    Lancet (London, England), 2001, Jul-07, Volume: 358, Issue:9275

    Topics: Adult; Basal Ganglia; Basal Ganglia Diseases; Biopsy; Brain; Brain Diseases; Choline; Creatine; Fati

2001
In vivo single-voxel proton MR spectroscopy in brain lesions with ring-like enhancement.
    NMR in biomedicine, 2001, Volume: 14, Issue:6

    Topics: Adult; Aged; Brain; Brain Abscess; Brain Diseases; Brain Neoplasms; Cerebral Infarction; Choline; Cr

2001
Diffuse metabolic abnormalities in reversible posterior leukoencephalopathy syndrome.
    AJNR. American journal of neuroradiology, 2002, Volume: 23, Issue:5

    Topics: Adult; Aspartic Acid; Brain Diseases; Choline; Confusion; Creatine; Female; Headache; Humans; Magnet

2002
1H and 31P magnetic resonance spectroscopy of the brain in degenerative cerebral disorders.
    Annals of neurology, 1992, Volume: 31, Issue:2

    Topics: Adult; Aspartic Acid; Atrophy; Brain; Brain Diseases; Child; Creatine; Demyelinating Diseases; Human

1992
[Effect of 1-beta-oxyethyl-2-phenyl-methyl-piperidine in 6 cases of diabetes insipidus in children].
    Archives francaises de pediatrie, 1968, Volume: 25, Issue:2

    Topics: Biopsy; Body Temperature; Body Weight; Brain Diseases; Calcium; Child; Child, Preschool; Chlorides;

1968