creatine has been researched along with BCKD Deficiency in 9 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, we evaluated the possible preventive effect of the co-administration of creatine plus pyruvate on the effects elicited by leucine administration to female Wistar rats during pregnancy and lactation on some oxidative stress parameters as well as the activities of some enzymes involved in the phosphoryltransfer network in the brain cortex and hippocampus of the offspring at 21 days of age." | 7.79 | Effect of leucine administration to female rats during pregnancy and lactation on oxidative stress and enzymes activities of phosphoryltransfer network in cerebral cortex and hippocampus of the offspring. ( Campos, AG; de Franceschi, ID; Feksa, LR; Rech, VC; Rieger, E; Rojas, DB; Vargas, AP; Wannmacher, CM, 2013) |
| " Considering that brain energy metabolism is possibly altered in MSUD, the objective of this study was to determine creatine kinase (CK) activity, a key enzyme of energy homeostasis, in C6 glioma cells exposed to BCKA." | 7.73 | Creatine and antioxidant treatment prevent the inhibition of creatine kinase activity and the morphological alterations of C6 glioma cells induced by the branched-chain alpha-keto acids accumulating in maple syrup urine disease. ( Funchal, C; Gottfried, C; Jacques-Silva, MC; Pessoa-Pureur, R; Santos, AQ; Schuck, PF; Wajner, M, 2006) |
| " In the present study, we evaluated the possible preventive effect of the co-administration of creatine plus pyruvate on the effects elicited by leucine administration to female Wistar rats during pregnancy and lactation on some oxidative stress parameters as well as the activities of some enzymes involved in the phosphoryltransfer network in the brain cortex and hippocampus of the offspring at 21 days of age." | 3.79 | Effect of leucine administration to female rats during pregnancy and lactation on oxidative stress and enzymes activities of phosphoryltransfer network in cerebral cortex and hippocampus of the offspring. ( Campos, AG; de Franceschi, ID; Feksa, LR; Rech, VC; Rieger, E; Rojas, DB; Vargas, AP; Wannmacher, CM, 2013) |
| " Considering that brain energy metabolism is possibly altered in MSUD, the objective of this study was to determine creatine kinase (CK) activity, a key enzyme of energy homeostasis, in C6 glioma cells exposed to BCKA." | 3.73 | Creatine and antioxidant treatment prevent the inhibition of creatine kinase activity and the morphological alterations of C6 glioma cells induced by the branched-chain alpha-keto acids accumulating in maple syrup urine disease. ( Funchal, C; Gottfried, C; Jacques-Silva, MC; Pessoa-Pureur, R; Santos, AQ; Schuck, PF; Wajner, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (77.78) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Muelly, ER | 1 |
| Moore, GJ | 1 |
| Bunce, SC | 1 |
| Mack, J | 1 |
| Bigler, DC | 1 |
| Morton, DH | 1 |
| Strauss, KA | 1 |
| de Franceschi, ID | 1 |
| Rieger, E | 1 |
| Vargas, AP | 1 |
| Rojas, DB | 1 |
| Campos, AG | 1 |
| Rech, VC | 1 |
| Feksa, LR | 1 |
| Wannmacher, CM | 1 |
| Jan, W | 1 |
| Zimmerman, RA | 1 |
| Wang, ZJ | 1 |
| Berry, GT | 1 |
| Kaplan, PB | 1 |
| Kaye, EM | 1 |
| Funchal, C | 4 |
| Gottfried, C | 3 |
| De Almeida, LM | 2 |
| Wajner, M | 6 |
| Pessoa-Pureur, R | 4 |
| Vasques, Vde C | 1 |
| Brinco, F | 1 |
| dos Santos, AQ | 1 |
| Schuck, PF | 1 |
| Santos, AQ | 1 |
| Jacques-Silva, MC | 1 |
| Tramontina, F | 1 |
| Quincozes dos Santos, A | 1 |
| Fraga de Souza, D | 1 |
| Gonçalves, CA | 1 |
| Barschak, AG | 1 |
| Marchesan, C | 1 |
| Sitta, A | 1 |
| Deon, M | 1 |
| Giugliani, R | 1 |
| Vargas, CR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Neuroimaging and Neuropsychological Outcomes in Urea Cycle Disorders[NCT02935283] | 56 participants (Anticipated) | Observational | 2016-08-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 other studies available for creatine and BCKD Deficiency
| Article | Year |
|---|---|
Biochemical correlates of neuropsychiatric illness in maple syrup urine disease.
Topics: Adolescent; Adult; Affect; Anxiety; Aspartic Acid; Attention; Brain; Case-Control Studies; Child; Ch | 2013 |
Effect of leucine administration to female rats during pregnancy and lactation on oxidative stress and enzymes activities of phosphoryltransfer network in cerebral cortex and hippocampus of the offspring.
Topics: Animals; Antioxidants; Cerebral Cortex; Creatine; Female; Hippocampus; Lactation; Leucine; Male; Map | 2013 |
MR diffusion imaging and MR spectroscopy of maple syrup urine disease during acute metabolic decompensation.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acids, Branched-Chain; Aspartic Acid; Basal | 2003 |
Evidence that the branched-chain alpha-keto acids accumulating in maple syrup urine disease induce morphological alterations and death in cultured astrocytes from rat cerebral cortex.
Topics: Actins; Animals; Animals, Newborn; Astrocytes; Brain; Cell Death; Cell Shape; Cells, Cultured; Cereb | 2004 |
Intrahippocampal administration of the branched-chain alpha-hydroxy acids accumulating in maple syrup urine disease compromises rat performance in aversive and non-aversive behavioral tasks.
Topics: Animals; Antioxidants; Avoidance Learning; Behavior, Animal; Creatine; Dizocilpine Maleate; Excitato | 2005 |
Morphological alterations and cell death provoked by the branched-chain alpha-amino acids accumulating in maple syrup urine disease in astrocytes from rat cerebral cortex.
Topics: Amino Acids, Branched-Chain; Animals; Astrocytes; Cell Death; Cell Nucleus; Cell Survival; Cells, Cu | 2005 |
Creatine and antioxidant treatment prevent the inhibition of creatine kinase activity and the morphological alterations of C6 glioma cells induced by the branched-chain alpha-keto acids accumulating in maple syrup urine disease.
Topics: Animals; Antioxidants; Cell Line, Tumor; Cell Shape; Creatine; Creatine Kinase; Glioma; Hemiterpenes | 2006 |
Effect of the branched-chain alpha-keto acids accumulating in maple syrup urine disease on S100B release from glial cells.
Topics: Animals; Brain; Cell Death; Cell Line, Tumor; Creatine; Dose-Response Relationship, Drug; Energy Met | 2007 |
Maple syrup urine disease in treated patients: biochemical and oxidative stress profiles.
Topics: Antioxidants; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Creatine; Glucose; Humans; Hydro-Lyas | 2008 |