Page last updated: 2024-10-17

creatine and Autosomal Dominant Cerebellar Ataxia, Type II

creatine has been researched along with Autosomal Dominant Cerebellar Ataxia, Type II in 9 studies

Research Excerpts

ExcerptRelevanceReference
"Autosomal dominant ataxia type 14 (SCA14) is a rare usually adult-onset progressive disorder with cerebellar neurodegeneration caused by mutations in protein kinase C gamma."1.42Cerebellar neurochemical alterations in spinocerebellar ataxia type 14 appear to include glutathione deficiency. ( Brandt, AU; Doss, S; Endres, M; Klockgether, T; Lux, S; Maul, S; Minnerop, M; Papazoglou, S; Paul, F; Rinnenthal, JL; Schmitz-Hübsch, T; Würfel, J, 2015)
"Autosomal-dominant spinocerebellar ataxia type 1 (SCA1) is an adult-onset progressive disorder with well-characterized neurodegeneration in the cerebellum and brainstem."1.40Metabolic evidence for cerebral neurodegeneration in spinocerebellar ataxia type 1. ( Brandt, AU; Doss, S; Endres, M; Oberwahrenbrock, T; Paul, F; Rinnenthal, JL, 2014)
"We reported a Japanese case of spinocerebellar ataxia type 6 (SCA6) with episodic ataxia type 2 (EA2) phenotype."1.33[A case of spinocerebellar ataxia type 6 with its initial symptom of episodic ataxia-like phenotype]. ( Ishikawa, K; Nakano, I; Nakao, K; Shimazaki, H; Takiyama, Y, 2006)
"Compared with control subjects, the SCA1 and SCA2 patients showed a decrease (P < 0."1.32Brainstem neurodegeneration correlates with clinical dysfunction in SCA1 but not in SCA2. A quantitative volumetric, diffusion and proton spectroscopy MR study. ( Belli, G; Cosottini, M; De Grandis, D; Della Nave, R; Filla, A; Foresti, S; Ginestroni, A; Guerrini, L; Lolli, F; Mascalchi, M; Piacentini, S; Plasmati, R; Salvi, F; Siciliano, G; Tessa, C, 2004)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (66.67)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Doss, S2
Brandt, AU2
Oberwahrenbrock, T1
Endres, M2
Paul, F2
Rinnenthal, JL2
Schmitz-Hübsch, T1
Papazoglou, S1
Lux, S1
Maul, S1
Würfel, J1
Klockgether, T1
Minnerop, M1
Wang, PS1
Chen, HC1
Wu, HM1
Lirng, JF1
Wu, YT1
Soong, BW1
Guerrini, L1
Lolli, F1
Ginestroni, A1
Belli, G1
Della Nave, R1
Tessa, C1
Foresti, S1
Cosottini, M1
Piacentini, S1
Salvi, F1
Plasmati, R1
De Grandis, D1
Siciliano, G1
Filla, A1
Mascalchi, M1
Harno, H1
Heikkinen, S1
Kaunisto, MA1
Kallela, M1
Häkkinen, AM1
Wessman, M1
Färkkilä, M1
Lundbom, N1
Shimazaki, H1
Nakao, K1
Ishikawa, K1
Takiyama, Y1
Nakano, I1
Boesch, SM2
Wolf, C1
Seppi, K1
Felber, S2
Wenning, GK1
Schocke, M2
Kaemmerer, WF1
Rodrigues, CM1
Steer, CJ1
Low, WC1
Bürk, K1
Hollosi, P1
Fornai, F1
Aichner, FT1
Poewe, W1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase 2 Study of 4-Aminopyridine for the Treatment of Episodic Ataxia Type 2[NCT01543750]Phase 20 participants (Actual)InterventionalWithdrawn
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for creatine and Autosomal Dominant Cerebellar Ataxia, Type II

ArticleYear
Differentiation of SCA2 from MSA-C using proton magnetic resonance spectroscopic imaging.
    Journal of magnetic resonance imaging : JMRI, 2007, Volume: 25, Issue:3

    Topics: Adult; Age of Onset; Aged; Aspartic Acid; Cerebellum; Choline; Creatine; Diagnosis, Differential; Fe

2007

Other Studies

8 other studies available for creatine and Autosomal Dominant Cerebellar Ataxia, Type II

ArticleYear
Metabolic evidence for cerebral neurodegeneration in spinocerebellar ataxia type 1.
    Cerebellum (London, England), 2014, Volume: 13, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Aspartic Acid; Brain; Cerebral Cortex; Choline; Creatine; Female;

2014
Cerebellar neurochemical alterations in spinocerebellar ataxia type 14 appear to include glutathione deficiency.
    Journal of neurology, 2015, Volume: 262, Issue:8

    Topics: Adult; Aged; Aspartic Acid; Cerebellum; Cerebral Cortex; Creatine; Female; Glutamic Acid; Glutathion

2015
Association between proton magnetic resonance spectroscopy measurements and CAG repeat number in patients with spinocerebellar ataxias 2, 3, or 6.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Adult; Age of Onset; Aged; Aspartic Acid; Case-Control Studies; Cerebellum; Creatine; Disease Progre

2012
Brainstem neurodegeneration correlates with clinical dysfunction in SCA1 but not in SCA2. A quantitative volumetric, diffusion and proton spectroscopy MR study.
    Brain : a journal of neurology, 2004, Volume: 127, Issue:Pt 8

    Topics: Adult; Aged; Aspartic Acid; Biomarkers; Brain Stem; Cerebellum; Creatine; Female; Humans; Magnetic R

2004
Decreased cerebellar total creatine in episodic ataxia type 2: a 1H MRS study.
    Neurology, 2005, Feb-08, Volume: 64, Issue:3

    Topics: Adolescent; Adult; Aspartic Acid; Calcium Channels; Cerebellum; Child; Choline; Creatine; Dysarthria

2005
[A case of spinocerebellar ataxia type 6 with its initial symptom of episodic ataxia-like phenotype].
    No to shinkei = Brain and nerve, 2006, Volume: 58, Issue:1

    Topics: Adult; Aspartic Acid; Brain Chemistry; Creatine; Female; Humans; Magnetic Resonance Imaging; Magneti

2006
Creatine-supplemented diet extends Purkinje cell survival in spinocerebellar ataxia type 1 transgenic mice but does not prevent the ataxic phenotype.
    Neuroscience, 2001, Volume: 103, Issue:3

    Topics: Animals; Ataxin-1; Ataxins; Bile Acids and Salts; Cell Count; Cell Survival; Cerebellum; Creatine; D

2001
Proton magnetic resonance spectroscopic imaging reveals differences in spinocerebellar ataxia types 2 and 6.
    Journal of magnetic resonance imaging : JMRI, 2001, Volume: 13, Issue:4

    Topics: Adult; Aspartic Acid; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy; Male; Midd

2001