creatine has been researched along with Autistic Disorder in 25 studies
Autistic Disorder: A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propionic acid (PPA) was injected intraperitoneally into 20 out of 30 rats for 5 days to establish an autism model." | 8.12 | Therapeutic effect of finasteride through its antiandrogenic and antioxidant role in a propionic acid-induced autism model: Demonstrated by behavioral tests, histological findings and MR spectroscopy. ( Bozkurt, MF; Erbas, O; Ozkul, B; Sever, IH, 2022) |
| "Creatine deficiency may play a role in the neurobiology of autism and may represent a treatable cause of autism." | 7.83 | Prevalence of Creatine Deficiency Syndromes in Children With Nonsyndromic Autism. ( Anagnostou, E; Bauman, M; Cameron, J; Chen, S; Kyriakopoulou, L; Loh, A; Nozzolillo, AA; Reynolds, A; Roberts, W; Scherer, SW; Schulze, A; Tsai, AC, 2016) |
| " We report an association between hydrogen proton magnetic resonance spectroscopy choline/creatine ratios and severity of autism as measured by the Children's Autistic Rating Scale (Pearson r = ." | 7.71 | Hydrogen proton magnetic resonance spectroscopy in autism: preliminary evidence of elevated choline/creatine ratio. ( Dunn, DW; Edwards-Brown, M; Feinberg, J; Sokol, DK, 2002) |
| "Autism is a heterogeneous pervasive developmental disorder with a poorly defined aetiology and pathophysiology." | 5.32 | Indolyl-3-acryloylglycine (IAG) is a putative diagnostic urinary marker for autism spectrum disorders. ( Anderson, R; Bull, G; Groundwater, PW; Lees, G; Lough, JW; Shattock, P; Whiteley, P, 2003) |
| "Propionic acid (PPA) was injected intraperitoneally into 20 out of 30 rats for 5 days to establish an autism model." | 4.12 | Therapeutic effect of finasteride through its antiandrogenic and antioxidant role in a propionic acid-induced autism model: Demonstrated by behavioral tests, histological findings and MR spectroscopy. ( Bozkurt, MF; Erbas, O; Ozkul, B; Sever, IH, 2022) |
| "Creatine Transporter Deficiency (CTD) is an inborn error of metabolism presenting with intellectual disability, behavioral disturbances and epilepsy." | 3.96 | Cyclocreatine treatment ameliorates the cognitive, autistic and epileptic phenotype in a mouse model of Creatine Transporter Deficiency. ( Alessandrì, MG; Baroncelli, L; Battini, R; Butt, M; Cacciante, F; Cerri, E; Cioni, G; Do, MT; Gennaro, M; Lupori, L; Mazziotti, R; McKew, JC; Pizzorusso, T; Putignano, E; Sagona, G, 2020) |
| "Creatine deficiency may play a role in the neurobiology of autism and may represent a treatable cause of autism." | 3.83 | Prevalence of Creatine Deficiency Syndromes in Children With Nonsyndromic Autism. ( Anagnostou, E; Bauman, M; Cameron, J; Chen, S; Kyriakopoulou, L; Loh, A; Nozzolillo, AA; Reynolds, A; Roberts, W; Scherer, SW; Schulze, A; Tsai, AC, 2016) |
| "We determined creatine/creatinine ratio in urine samples from 1600 unrelated male patients with mental retardation and/or autism." | 3.74 | Creatine transporter deficiency: prevalence among patients with mental retardation and pitfalls in metabolite screening. ( Arias, A; Artuch, R; Briones, P; Campistol, J; Corbella, M; Fons, C; García-Villoria, J; Ormazabal, A; Pàmpols, T; Pineda, M; Poo, P; Ribes, A; Salomons, GS; Sempere, A; Vilaseca, MA, 2007) |
| "In 22 children with autism, 5 to 16 years old, and 20 age-matched healthy control subjects, (1)H-MRSI assessed levels of N-acetyl compounds (NAA), choline compounds (Cho), and creatine plus phosphocreatine (Cr) at 272 msec echo-time and 1." | 3.72 | Proton magnetic resonance spectroscopic imaging of the brain in childhood autism. ( Alger, JR; Blanton, RE; Fadale, D; Guthrie, D; Levitt, JG; McCracken, JT; O'Neill, J; Smalley, S; Toga, AW, 2003) |
| " We report an association between hydrogen proton magnetic resonance spectroscopy choline/creatine ratios and severity of autism as measured by the Children's Autistic Rating Scale (Pearson r = ." | 3.71 | Hydrogen proton magnetic resonance spectroscopy in autism: preliminary evidence of elevated choline/creatine ratio. ( Dunn, DW; Edwards-Brown, M; Feinberg, J; Sokol, DK, 2002) |
| "© 2015 International Society for Autism Research, Wiley Periodicals, Inc." | 1.43 | Biochemistry of the cingulate cortex in autism: An MR spectroscopy study. ( Kana, RK; Lahti, AC; Libero, LE; Reid, MA; Salibi, N; White, DM, 2016) |
| "Although autism spectrum disorders (ASDs) are highly heritable, MRS studies have not included relatives of persons with ASD." | 1.39 | Increased glutamate concentration in the auditory cortex of persons with autism and first-degree relatives: a (1)H-MRS study. ( Brown, MS; Hepburn, S; Rojas, DC; Singel, D, 2013) |
| "The diagnosis of autism was established by neurologist, psychiatrist and psychologist in every case." | 1.38 | Metabolite alterations in autistic children: a 1H MR spectroscopy study. ( Kubas, B; Kułak, W; Lebkowska, U; Sobaniec, W; Tarasow, E; Walecki, J, 2012) |
| "Choline/creatine was also significantly elevated in the left hippocampus-amygdala and cerebellar regions of children with autism spectrum disorder." | 1.35 | 1H-magnetic resonance spectroscopy markers of cognitive and language ability in clinical subtypes of autism spectrum disorders. ( Azizian, A; DeVincent, C; Gabis, L; Kesner-Baruch, Y; Pomeroy, J; Roche, P; Tudorica, A, 2008) |
| "Autism is a heterogeneous pervasive developmental disorder with a poorly defined aetiology and pathophysiology." | 1.32 | Indolyl-3-acryloylglycine (IAG) is a putative diagnostic urinary marker for autism spectrum disorders. ( Anderson, R; Bull, G; Groundwater, PW; Lees, G; Lough, JW; Shattock, P; Whiteley, P, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (8.00) | 18.2507 |
| 2000's | 11 (44.00) | 29.6817 |
| 2010's | 8 (32.00) | 24.3611 |
| 2020's | 4 (16.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grechanyi, SV | 1 |
| Suf El-Zhil, LR | 1 |
| Ivanov, DO | 1 |
| Pozdnyakova, OF | 1 |
| Sergeev, AM | 1 |
| Atamanova, EE | 1 |
| Pozdnyakov, AV | 1 |
| Sever, IH | 1 |
| Ozkul, B | 1 |
| Bozkurt, MF | 1 |
| Erbas, O | 1 |
| Moravej, H | 1 |
| Inaloo, S | 1 |
| Nahid, S | 1 |
| Mazloumi, S | 1 |
| Nemati, H | 1 |
| Moosavian, T | 1 |
| Nasiri, J | 1 |
| Ghasemi, F | 1 |
| Alaei, MR | 1 |
| Dalili, S | 1 |
| Aminzadeh, M | 1 |
| Katibeh, P | 1 |
| Amirhakimi, A | 1 |
| Yazdani, N | 1 |
| Ilkhanipoor, H | 1 |
| Afshar, Z | 1 |
| Hadipour, F | 1 |
| Hadipour, Z | 1 |
| Cacciante, F | 1 |
| Gennaro, M | 1 |
| Sagona, G | 1 |
| Mazziotti, R | 1 |
| Lupori, L | 1 |
| Cerri, E | 1 |
| Putignano, E | 1 |
| Butt, M | 1 |
| Do, MT | 1 |
| McKew, JC | 1 |
| Alessandrì, MG | 1 |
| Battini, R | 1 |
| Cioni, G | 1 |
| Pizzorusso, T | 1 |
| Baroncelli, L | 1 |
| Libero, LE | 1 |
| Reid, MA | 1 |
| White, DM | 1 |
| Salibi, N | 1 |
| Lahti, AC | 1 |
| Kana, RK | 1 |
| Schulze, A | 1 |
| Bauman, M | 1 |
| Tsai, AC | 1 |
| Reynolds, A | 1 |
| Roberts, W | 1 |
| Anagnostou, E | 1 |
| Cameron, J | 1 |
| Nozzolillo, AA | 1 |
| Chen, S | 1 |
| Kyriakopoulou, L | 1 |
| Scherer, SW | 1 |
| Loh, A | 1 |
| Hardan, AY | 1 |
| Minshew, NJ | 1 |
| Melhem, NM | 1 |
| Srihari, S | 1 |
| Jo, B | 1 |
| Bansal, R | 1 |
| Keshavan, MS | 1 |
| Stanley, JA | 1 |
| Kleinhans, NM | 1 |
| Richards, T | 1 |
| Weaver, KE | 1 |
| Liang, O | 1 |
| Dawson, G | 3 |
| Aylward, E | 1 |
| Suzuki, K | 1 |
| Nishimura, K | 1 |
| Sugihara, G | 1 |
| Nakamura, K | 1 |
| Tsuchiya, KJ | 1 |
| Matsumoto, K | 1 |
| Takebayashi, K | 1 |
| Isoda, H | 1 |
| Sakahara, H | 1 |
| Sugiyama, T | 1 |
| Tsujii, M | 1 |
| Takei, N | 1 |
| Mori, N | 1 |
| Nasrallah, F | 1 |
| Feki, M | 1 |
| Kaabachi, N | 1 |
| Fujii, E | 1 |
| Mori, K | 2 |
| Miyazaki, M | 2 |
| Hashimoto, T | 3 |
| Harada, M | 3 |
| Kagami, S | 1 |
| Vamecq, J | 1 |
| Joncquel-Chevalier Curt, M | 1 |
| Mention-Mulliez, K | 1 |
| Dobbelaere, D | 1 |
| Briand, G | 1 |
| Kubas, B | 1 |
| Kułak, W | 1 |
| Sobaniec, W | 1 |
| Tarasow, E | 1 |
| Lebkowska, U | 1 |
| Walecki, J | 1 |
| Brown, MS | 1 |
| Singel, D | 1 |
| Hepburn, S | 1 |
| Rojas, DC | 1 |
| Friedman, SD | 2 |
| Shaw, DW | 2 |
| Artru, AA | 2 |
| Richards, TL | 1 |
| Gardner, J | 1 |
| Posse, S | 1 |
| Dager, SR | 2 |
| Bull, G | 1 |
| Shattock, P | 1 |
| Whiteley, P | 1 |
| Anderson, R | 1 |
| Groundwater, PW | 1 |
| Lough, JW | 1 |
| Lees, G | 1 |
| Levitt, JG | 1 |
| O'Neill, J | 1 |
| Blanton, RE | 1 |
| Smalley, S | 1 |
| Fadale, D | 1 |
| McCracken, JT | 1 |
| Guthrie, D | 1 |
| Toga, AW | 1 |
| Alger, JR | 1 |
| Petropoulos, H | 1 |
| Page, LA | 1 |
| Daly, E | 1 |
| Schmitz, N | 1 |
| Simmons, A | 1 |
| Toal, F | 1 |
| Deeley, Q | 1 |
| Ambery, F | 1 |
| McAlonan, GM | 1 |
| Murphy, KC | 1 |
| Murphy, DG | 1 |
| Arias, A | 1 |
| Corbella, M | 1 |
| Fons, C | 1 |
| Sempere, A | 1 |
| García-Villoria, J | 1 |
| Ormazabal, A | 1 |
| Poo, P | 1 |
| Pineda, M | 1 |
| Vilaseca, MA | 1 |
| Campistol, J | 1 |
| Briones, P | 1 |
| Pàmpols, T | 1 |
| Salomons, GS | 1 |
| Ribes, A | 1 |
| Artuch, R | 1 |
| Vasconcelos, MM | 1 |
| Brito, AR | 1 |
| Domingues, RC | 1 |
| da Cruz, LC | 1 |
| Gasparetto, EL | 1 |
| Werner, J | 1 |
| Gonçalves, JP | 1 |
| Gabis, L | 1 |
| Azizian, A | 1 |
| DeVincent, C | 1 |
| Tudorica, A | 1 |
| Kesner-Baruch, Y | 1 |
| Roche, P | 1 |
| Pomeroy, J | 1 |
| Tayama, M | 1 |
| Yoneda, Y | 2 |
| Yoshimoto, T | 1 |
| Miyoshi, H | 1 |
| Tanouchi, M | 1 |
| Kuroda, Y | 1 |
| Kawano, N | 1 |
| Fukuda, K | 1 |
| Endo, S | 1 |
| Yamaue, T | 1 |
| Miyoshi, K | 1 |
| Sokol, DK | 1 |
| Dunn, DW | 1 |
| Edwards-Brown, M | 1 |
| Feinberg, J | 1 |
1 review available for creatine and Autistic Disorder
| Article | Year |
|---|---|
Creatine and creatine deficiency syndromes: biochemical and clinical aspects.
Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Autistic Disorder; Child; Creatine; Epile | 2010 |
1 trial available for creatine and Autistic Disorder
| Article | Year |
|---|---|
Regional brain chemical alterations in young children with autism spectrum disorder.
Topics: Age Distribution; Age Factors; Aspartic Acid; Autistic Disorder; Brain; Cell Count; Child, Preschool | 2003 |
23 other studies available for creatine and Autistic Disorder
| Article | Year |
|---|---|
[Proton magnetic resonance spectroscopy in children with atypical autism comorbid with psychomotor disinhibition syndrome].
Topics: Aspartic Acid; Autistic Disorder; Brain; Choline; Creatine; Female; Humans; Magnetic Resonance Spect | 2021 |
Therapeutic effect of finasteride through its antiandrogenic and antioxidant role in a propionic acid-induced autism model: Demonstrated by behavioral tests, histological findings and MR spectroscopy.
Topics: Animals; Antioxidants; Autistic Disorder; Behavior Rating Scale; Creatine; Finasteride; Lactic Acid; | 2022 |
Inborn Errors of Metabolism Associated With Autism Among Children: A Multicenter Study from Iran.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acids; Autism Spectrum Disorder; Autistic Di | 2023 |
Cyclocreatine treatment ameliorates the cognitive, autistic and epileptic phenotype in a mouse model of Creatine Transporter Deficiency.
Topics: Animals; Autistic Disorder; Blood-Brain Barrier; Brain Diseases, Metabolic, Inborn; Cerebrovascular | 2020 |
Biochemistry of the cingulate cortex in autism: An MR spectroscopy study.
Topics: Adult; Aspartic Acid; Autistic Disorder; Choline; Creatine; Female; Gyrus Cinguli; Humans; Magnetic | 2016 |
Prevalence of Creatine Deficiency Syndromes in Children With Nonsyndromic Autism.
Topics: Adolescent; Autistic Disorder; Child; Child, Preschool; Creatine; Deficiency Diseases; Female; Human | 2016 |
An MRI and proton spectroscopy study of the thalamus in children with autism.
Topics: Adolescent; Aspartic Acid; Autistic Disorder; Child; Choline; Creatine; Dominance, Cerebral; Humans; | 2008 |
Brief report: biochemical correlates of clinical impairment in high functioning autism and Asperger's disorder.
Topics: Adolescent; Adult; Amygdala; Aspartic Acid; Asperger Syndrome; Autistic Disorder; Brain Mapping; Cas | 2009 |
Metabolite alterations in the hippocampus of high-functioning adult subjects with autism.
Topics: Adolescent; Adult; Aggression; Aspartic Acid; Autistic Disorder; Cerebellum; Choline; Creatine; Hipp | 2010 |
Function of the frontal lobe in autistic individuals: a proton magnetic resonance spectroscopic study.
Topics: Adolescent; Aspartic Acid; Autistic Disorder; Child; Child, Preschool; Choline; Creatine; Female; Fr | 2010 |
Rise in brain GABA to further stress the metabolic link between valproate and creatine.
Topics: Ammonia; Autistic Disorder; Brain; Creatine; Humans; Valproic Acid | 2011 |
Metabolite alterations in autistic children: a 1H MR spectroscopy study.
Topics: Adolescent; Aspartic Acid; Autistic Disorder; Child; Choline; Creatine; Female; gamma-Aminobutyric A | 2012 |
Increased glutamate concentration in the auditory cortex of persons with autism and first-degree relatives: a (1)H-MRS study.
Topics: Adult; Auditory Cortex; Autistic Disorder; Choline; Creatine; Female; Glutamic Acid; Humans; Inosito | 2013 |
Indolyl-3-acryloylglycine (IAG) is a putative diagnostic urinary marker for autism spectrum disorders.
Topics: Adolescent; Adult; Age Factors; Autistic Disorder; Biological Assay; Child; Child, Preschool; Chroma | 2003 |
Proton magnetic resonance spectroscopic imaging of the brain in childhood autism.
Topics: Adolescent; Aspartic Acid; Autistic Disorder; Brain; Brain Mapping; Case-Control Studies; Child; Chi | 2003 |
Gray and white matter brain chemistry in young children with autism.
Topics: Aspartic Acid; Autistic Disorder; Brain; Brain Chemistry; Child, Preschool; Choline; Creatine; Cross | 2006 |
In vivo 1H-magnetic resonance spectroscopy study of amygdala-hippocampal and parietal regions in autism.
Topics: Adult; Amygdala; Autistic Disorder; Creatine; Female; Glutamates; Glutamine; Hippocampus; Humans; In | 2006 |
Creatine transporter deficiency: prevalence among patients with mental retardation and pitfalls in metabolite screening.
Topics: Autistic Disorder; Child; Child, Preschool; Creatine; Creatinine; Glycine; Humans; Infant; Intellect | 2007 |
Proton magnetic resonance spectroscopy in school-aged autistic children.
Topics: Analysis of Variance; Aspartic Acid; Autistic Disorder; Brain; Brain Chemistry; Case-Control Studies | 2008 |
1H-magnetic resonance spectroscopy markers of cognitive and language ability in clinical subtypes of autism spectrum disorders.
Topics: Adolescent; Amygdala; Analysis of Variance; Aspartic Acid; Asperger Syndrome; Autistic Disorder; Bio | 2008 |
Differences in brain metabolites between patients with autism and mental retardation as detected by in vivo localized proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Autistic Disorder; Brain; Child; Child, Preschool; Choline; Creatine; Female; Humans; | 1997 |
Proton magnetic resonance spectroscopy of the brain in three cases of Rett syndrome: comparison with autism and normal controls.
Topics: Adolescent; Adult; Aspartic Acid; Autistic Disorder; Brain; Child; Child, Preschool; Choline; Creati | 1998 |
Hydrogen proton magnetic resonance spectroscopy in autism: preliminary evidence of elevated choline/creatine ratio.
Topics: Autistic Disorder; Brain; Child; Child, Preschool; Choline; Creatine; Female; Humans; Hydrogen Bondi | 2002 |