creatine has been researched along with Autism Spectrum Disorder in 14 studies
Autism Spectrum Disorder: Wide continuum of associated cognitive and neurobehavioral disorders, including, but not limited to, three core-defining features: impairments in socialization, impairments in verbal and nonverbal communication, and restricted and repetitive patterns of behaviors. (from DSM-V)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The excitatory-inhibitory imbalance hypothesis postulates dysregulation of the gamma-aminobutyric acid (GABA) and glutamate (Glu) neurotransmitter systems as a common underlying deficit in individuals with autism spectrum disorders (ASD)." | 4.12 | Increased prefrontal GABA concentrations in adults with autism spectrum disorders. ( Dacko, M; Domschke, K; Düppers, AL; Ebert, D; Endres, D; Fangmeier, T; Lange, T; Maier, S; Nickel, K; Perlov, E; Riedel, A; Runge, K; Tebartz van Elst, L, 2022) |
| " We illustrate these limitations of norm-referenced scores, and relative advantages of ability scores, using data from studies of autism spectrum disorder and creatine transporter deficiency." | 3.96 | Person Ability Scores as an Alternative to Norm-Referenced Scores as Outcome Measures in Studies of Neurodevelopmental Disorders. ( Akshoomoff, N; Anselm, I; Barshop, BA; Bennett, A; Berry, L; Berry-Kravis, E; Bianconi, S; Bruchey, A; Cecil, KM; Davis, RJ; Farmer, CA; Ficicioglu, C; Goin-Kochel, RP; Guthrie, W; Kaat, AJ; Koeberl, D; Leonczyk, C; Love-Nichols, J; Mamak, E; Mercimek-Andrews, S; Miller, JS; Porter, FD; Spiridigliozzi, GA; Sullivan, N; Sutton, VR; Thomas, RP; Thurm, A; Udhnani, MD; Wainer, A; Waisbren, SE, 2020) |
| "Creatine transporter deficiency (CTD) is an X-linked, neurometabolic disorder associated with intellectual disability that is characterized by brain creatine (Cr) deficiency and caused by mutations in SLC6A8, the Cr transporter 1 protein gene." | 3.83 | Creatine Transporter Deficiency: Screening of Males with Neurodevelopmental Disorders and Neurocognitive Characterization of a Case. ( Carrillo, N; DʼSouza, P; Himelstein, D; Jiang, S; Longo, N; Olatunji, D; Pasquali, M; Rennert, O; Salomons, GS; Swedo, S; Thurm, A, 2016) |
| "The sister showed additional muscular hypotonia and more pronounced dysmorphic features compared to her brother." | 1.62 | Locus heterogeneity in two siblings presenting with developmental delay, intellectual disability and autism spectrum disorder. ( Boy, N; Brugger, M; Brunet, T; Orec, LE; Schwaibold, EMC; Wagner, M, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (50.00) | 24.3611 |
| 2020's | 7 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maier, S | 1 |
| Düppers, AL | 1 |
| Runge, K | 1 |
| Dacko, M | 1 |
| Lange, T | 1 |
| Fangmeier, T | 1 |
| Riedel, A | 1 |
| Ebert, D | 1 |
| Endres, D | 1 |
| Domschke, K | 1 |
| Perlov, E | 1 |
| Nickel, K | 1 |
| Tebartz van Elst, L | 1 |
| Moravej, H | 1 |
| Inaloo, S | 1 |
| Nahid, S | 1 |
| Mazloumi, S | 1 |
| Nemati, H | 1 |
| Moosavian, T | 1 |
| Nasiri, J | 1 |
| Ghasemi, F | 1 |
| Alaei, MR | 1 |
| Dalili, S | 1 |
| Aminzadeh, M | 1 |
| Katibeh, P | 1 |
| Amirhakimi, A | 1 |
| Yazdani, N | 1 |
| Ilkhanipoor, H | 1 |
| Afshar, Z | 1 |
| Hadipour, F | 1 |
| Hadipour, Z | 1 |
| Edmondson, DA | 1 |
| Xia, P | 1 |
| McNally Keehn, R | 1 |
| Dydak, U | 1 |
| Keehn, B | 1 |
| Yıldız, Y | 1 |
| Göçmen, R | 1 |
| Yaramış, A | 1 |
| Coşkun, T | 1 |
| Haliloğlu, G | 1 |
| Brugger, M | 1 |
| Brunet, T | 1 |
| Wagner, M | 1 |
| Orec, LE | 1 |
| Schwaibold, EMC | 1 |
| Boy, N | 1 |
| Farmer, CA | 1 |
| Kaat, AJ | 1 |
| Thurm, A | 3 |
| Anselm, I | 1 |
| Akshoomoff, N | 1 |
| Bennett, A | 1 |
| Berry, L | 1 |
| Bruchey, A | 1 |
| Barshop, BA | 1 |
| Berry-Kravis, E | 1 |
| Bianconi, S | 2 |
| Cecil, KM | 1 |
| Davis, RJ | 1 |
| Ficicioglu, C | 1 |
| Porter, FD | 2 |
| Wainer, A | 1 |
| Goin-Kochel, RP | 1 |
| Leonczyk, C | 1 |
| Guthrie, W | 1 |
| Koeberl, D | 1 |
| Love-Nichols, J | 1 |
| Mamak, E | 1 |
| Mercimek-Andrews, S | 1 |
| Thomas, RP | 1 |
| Spiridigliozzi, GA | 1 |
| Sullivan, N | 1 |
| Sutton, VR | 1 |
| Udhnani, MD | 1 |
| Waisbren, SE | 1 |
| Miller, JS | 1 |
| Levin, MD | 1 |
| Smith, A | 1 |
| Cawley, NX | 1 |
| Do, AD | 1 |
| Hammond, D | 1 |
| Grafstein, JF | 1 |
| Miller, J | 1 |
| Perreault, J | 1 |
| Noguchi, A | 1 |
| Springer, D | 1 |
| Kozel, BA | 1 |
| Spurney, CF | 1 |
| Wassif, CA | 1 |
| Yu, ZX | 1 |
| Schulze, A | 1 |
| Hannah-Shmouni, F | 1 |
| Ito, H | 1 |
| Mori, K | 1 |
| Harada, M | 1 |
| Hisaoka, S | 1 |
| Toda, Y | 1 |
| Mori, T | 1 |
| Goji, A | 1 |
| Abe, Y | 1 |
| Miyazaki, M | 1 |
| Kagami, S | 1 |
| Aydin, HI | 1 |
| Libero, LE | 1 |
| DeRamus, TP | 1 |
| Lahti, AC | 1 |
| Deshpande, G | 1 |
| Kana, RK | 1 |
| Hardan, AY | 1 |
| Fung, LK | 1 |
| Frazier, T | 1 |
| Berquist, SW | 1 |
| Minshew, NJ | 1 |
| Keshavan, MS | 1 |
| Stanley, JA | 1 |
| Campistol, J | 1 |
| Díez-Juan, M | 1 |
| Callejón, L | 1 |
| Fernandez-De Miguel, A | 1 |
| Casado, M | 1 |
| Garcia Cazorla, A | 1 |
| Lozano, R | 1 |
| Artuch, R | 1 |
| Himelstein, D | 1 |
| DʼSouza, P | 1 |
| Rennert, O | 1 |
| Jiang, S | 1 |
| Olatunji, D | 1 |
| Longo, N | 1 |
| Pasquali, M | 1 |
| Swedo, S | 1 |
| Salomons, GS | 1 |
| Carrillo, N | 1 |
| Drenthen, GS | 1 |
| Barendse, EM | 1 |
| Aldenkamp, AP | 1 |
| van Veenendaal, TM | 1 |
| Puts, NA | 1 |
| Edden, RA | 1 |
| Zinger, S | 1 |
| Thoonen, G | 1 |
| Hendriks, MP | 1 |
| Kessels, RP | 1 |
| Jansen, JF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Creatine Supplementation in Autism Spectrum Disorder: a Randomized Placebo-controlled Trial[NCT04498078] | 20 participants (Actual) | Interventional | 2022-01-15 | Active, not recruiting | |||
| Clinical and Immunological Investigations of Subtypes of Autism[NCT00298246] | 557 participants (Actual) | Observational | 2006-02-22 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
14 other studies available for creatine and Autism Spectrum Disorder
| Article | Year |
|---|---|
Increased prefrontal GABA concentrations in adults with autism spectrum disorders.
Topics: Adult; Autism Spectrum Disorder; Creatine; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans | 2022 |
Inborn Errors of Metabolism Associated With Autism Among Children: A Multicenter Study from Iran.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acids; Autism Spectrum Disorder; Autistic Di | 2023 |
A Magnetic Resonance Spectroscopy Study of Superior Visual Search Abilities in Children with Autism Spectrum Disorder.
Topics: Adolescent; Aspartic Acid; Attention; Autism Spectrum Disorder; Brain; Child; Creatine; Female; gamm | 2020 |
Creatine Transporter Deficiency Presenting as Autism Spectrum Disorder.
Topics: Autism Spectrum Disorder; Brain; Brain Diseases, Metabolic, Inborn; Child; Creatine; Creatinine; Dis | 2020 |
Locus heterogeneity in two siblings presenting with developmental delay, intellectual disability and autism spectrum disorder.
Topics: Autism Spectrum Disorder; Brain Diseases, Metabolic, Inborn; Child; Chromosomes, Human, Pair 16; Com | 2021 |
Person Ability Scores as an Alternative to Norm-Referenced Scores as Outcome Measures in Studies of Neurodevelopmental Disorders.
Topics: Autism Spectrum Disorder; Brain Diseases, Metabolic, Inborn; Child; Creatine; Humans; Mental Retarda | 2020 |
X-linked creatine transporter deficiency results in prolonged QTc and increased sudden death risk in humans and disease model.
Topics: Animals; Autism Spectrum Disorder; Brain Diseases, Metabolic, Inborn; Creatine; Cross-Sectional Stud | 2021 |
A Proton Magnetic Resonance Spectroscopic Study in Autism Spectrum Disorder Using a 3-Tesla Clinical Magnetic Resonance Imaging (MRI) System: The Anterior Cingulate Cortex and the Left Cerebellum.
Topics: Adolescent; Aspartic Acid; Autism Spectrum Disorder; Cerebellum; Child; Child, Preschool; Choline; C | 2017 |
Creatine Transporter Deficiency in Two Brothers with Autism Spectrum Disorder.
Topics: Adolescent; Arginine; Autism Spectrum Disorder; Brain Diseases, Metabolic, Inborn; Child; Creatine; | 2018 |
Multimodal neuroimaging based classification of autism spectrum disorder using anatomical, neurochemical, and white matter correlates.
Topics: Adult; Anisotropy; Aspartic Acid; Autism Spectrum Disorder; Brain; Broca Area; Case-Control Studies; | 2015 |
A proton spectroscopy study of white matter in children with autism.
Topics: Adolescent; Aspartic Acid; Autism Spectrum Disorder; Child; Creatine; Humans; Magnetic Resonance Spe | 2016 |
Inborn error metabolic screening in individuals with nonsyndromic autism spectrum disorders.
Topics: Adolescent; Autism Spectrum Disorder; Child; Child, Preschool; Chromatography, High Pressure Liquid; | 2016 |
Creatine Transporter Deficiency: Screening of Males with Neurodevelopmental Disorders and Neurocognitive Characterization of a Case.
Topics: Autism Spectrum Disorder; Brain Diseases, Metabolic, Inborn; Child; Creatine; Developmental Disabili | 2016 |
Altered neurotransmitter metabolism in adolescents with high-functioning autism.
Topics: Adolescent; Autism Spectrum Disorder; Creatine; Female; gamma-Aminobutyric Acid; Glutamic Acid; Huma | 2016 |