creatine has been researched along with Aura in 59 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The ratios of glutamate (Glu) and glutamate + glutamine (Glx) to total creatine (Glu/tCr and Glx/tCr) in the tumor were associated with epilepsy history." | 8.12 | Glutamic Acid and Total Creatine as Predictive Markers for Epilepsy in Glioblastoma by Using Magnetic Resonance Spectroscopy Before Surgery. ( Fujita, Y; Hashiguchi, M; Kohmura, E; Kohta, M; Maeyama, M; Nagashima, H; Nakai, T; Sasayama, T; Somiya, Y; Tanaka, H; Tanaka, K; Uozumi, Y, 2022) |
| "This article reports the clinical and genetic features of two cases of cerebral creatine deficiency syndrome I (CCDSI) caused by SLC6A8 gene mutations." | 7.96 | [Clinical features and SLC6A8 gene mutations of cerebral creatine deficiency syndrome I: an analysis of two families]. ( Dong, XR; Sun, WH; Wang, HJ; Wang, Y; Wu, BB; Wu, MY; Xiao, FF; Zhang, P; Zhou, WH; Zhuang, DY, 2020) |
| "Proton magnetic resonance spectroscopy analysis showed that the ratio of glutamate/glutamine to creatine (Glx/Cr) in the right hippocampus was significantly increased in patients with moderate depression and correlated positively with HAMD scores." | 7.79 | Increased ratio of glutamate/glutamine to creatine in the right hippocampus contributes to depressive symptoms in patients with epilepsy. ( Chen, CZ; Cheng, WZ; Ding, J; Fan, W; Li, X; Liang, L; Mao, LY; Peng, WF; Wang, X, 2013) |
| " We, therefore, utilized these methods to assess changes in glucose metabolism and metabolites in the rat lithium-pilocarpine model of epilepsy as markers of epileptogenesis from baseline to chronic spontaneous recurrent seizures (SRS)." | 7.78 | Changes in glucose metabolism and metabolites during the epileptogenic process in the lithium-pilocarpine model of epilepsy. ( Chung, JH; Im, KC; Kang, JK; Kim, JS; Kim, KS; Kim, ST; Kim, YI; Lee, EM; Park, GY; Shon, YM; Woo, CW, 2012) |
| "In order to confirm the roles of creatine (Cr) in epilepsy, we investigated the anti-convulsive effects of Cr, creatine transporter (CRT) and creatine kinases (CKs) against chemical-induced acute seizure activity and chronic epileptic seizure activity." | 7.76 | Effects of creatine and β-guanidinopropionic acid and alterations in creatine transporter and creatine kinases expression in acute seizure and chronic epilepsy models. ( Choi, SY; Kang, TC; Kim, DW; Kim, JE; Kwon, OS; Ryu, HJ; Song, HK; Yeo, SI, 2010) |
| "Disorders of creatine synthesis or its transporter resulting in neurological impairment with mental retardation and epilepsy have only been recognized in recent years." | 7.74 | Severe epilepsy in X-linked creatine transporter defect (CRTR-D). ( Baglietto, MG; Battaglia, FM; Caruso, U; Gaggero, R; Jakobs, C; Mancardi, MM; Rossi, A; Salomons, GS; Schiaffino, MC; Veneselli, E; Zara, F, 2007) |
| "Vigabatrin (VGB) is a new antiepileptic drug that increases the human brain gamma-aminobutyric acid (GABA) level by irreversibly inhibiting GABA transaminase." | 6.70 | Effects of vigabatrin on brain GABA+/CR signals in patients with epilepsy monitored by 1H-NMR-spectroscopy: responder characteristics. ( Boesiger, P; Duc, CO; Meier, D; Mueller, SG; Russ, W; Weber, B; Weber, OM; Wieser, HG, 2001) |
| "Epilepsy is one of the main symptoms in GAMT and CT1 deficiency, whereas the occurrence of febrile convulsions in infancy is a relatively common presenting symptom in all the three above-mentioned diseases." | 6.49 | Inborn errors of creatine metabolism and epilepsy. ( Battini, R; Cioni, G; Leuzzi, V; Mastrangelo, M, 2013) |
| "Epilepsy is often considered to be a progressive neurological disease, and the nature of this progression remains unclear." | 5.72 | Insights into the development of pentylenetetrazole-induced epileptic seizures from dynamic metabolomic changes. ( Cheng, P; Jia, P; Liao, S; Meng, K; Xiao, C; Xu, R; Zhao, X; Zheng, X, 2022) |
| "Although epilepsy was not affected by orally administered creatine (400 to 500 mg/kg per day), this treatment resulted in clinical improvement and an increase of creatine in cerebrospinal fluid and brain tissue." | 5.30 | Creatine deficiency syndrome caused by guanidinoacetate methyltransferase deficiency: diagnostic tools for a new inborn error of metabolism. ( Bachert, P; Bremer, HJ; De Deyn, PP; Hess, T; Knopp, MV; Marescau, B; Mayatepek, E; Rating, D; Schulze, A; Wevers, R, 1997) |
| "The ratios of glutamate (Glu) and glutamate + glutamine (Glx) to total creatine (Glu/tCr and Glx/tCr) in the tumor were associated with epilepsy history." | 4.12 | Glutamic Acid and Total Creatine as Predictive Markers for Epilepsy in Glioblastoma by Using Magnetic Resonance Spectroscopy Before Surgery. ( Fujita, Y; Hashiguchi, M; Kohmura, E; Kohta, M; Maeyama, M; Nagashima, H; Nakai, T; Sasayama, T; Somiya, Y; Tanaka, H; Tanaka, K; Uozumi, Y, 2022) |
| "This article reports the clinical and genetic features of two cases of cerebral creatine deficiency syndrome I (CCDSI) caused by SLC6A8 gene mutations." | 3.96 | [Clinical features and SLC6A8 gene mutations of cerebral creatine deficiency syndrome I: an analysis of two families]. ( Dong, XR; Sun, WH; Wang, HJ; Wang, Y; Wu, BB; Wu, MY; Xiao, FF; Zhang, P; Zhou, WH; Zhuang, DY, 2020) |
| "Creatine Transporter Deficiency (CTD) is an inborn error of metabolism presenting with intellectual disability, behavioral disturbances and epilepsy." | 3.96 | Cyclocreatine treatment ameliorates the cognitive, autistic and epileptic phenotype in a mouse model of Creatine Transporter Deficiency. ( Alessandrì, MG; Baroncelli, L; Battini, R; Butt, M; Cacciante, F; Cerri, E; Cioni, G; Do, MT; Gennaro, M; Lupori, L; Mazziotti, R; McKew, JC; Pizzorusso, T; Putignano, E; Sagona, G, 2020) |
| "Proton magnetic resonance spectroscopy analysis showed that the ratio of glutamate/glutamine to creatine (Glx/Cr) in the right hippocampus was significantly increased in patients with moderate depression and correlated positively with HAMD scores." | 3.79 | Increased ratio of glutamate/glutamine to creatine in the right hippocampus contributes to depressive symptoms in patients with epilepsy. ( Chen, CZ; Cheng, WZ; Ding, J; Fan, W; Li, X; Liang, L; Mao, LY; Peng, WF; Wang, X, 2013) |
| " We, therefore, utilized these methods to assess changes in glucose metabolism and metabolites in the rat lithium-pilocarpine model of epilepsy as markers of epileptogenesis from baseline to chronic spontaneous recurrent seizures (SRS)." | 3.78 | Changes in glucose metabolism and metabolites during the epileptogenic process in the lithium-pilocarpine model of epilepsy. ( Chung, JH; Im, KC; Kang, JK; Kim, JS; Kim, KS; Kim, ST; Kim, YI; Lee, EM; Park, GY; Shon, YM; Woo, CW, 2012) |
| "Metabolite maps of N-acetyl aspartate, choline and creatine were generated using (1)H-CSI data from the brain of healthy volunteers and patients with tumor and epilepsy." | 3.76 | Grid-free interactive and automated data processing for MR chemical shift imaging data. ( Confort-Gouny, S; Cozzone, PJ; Guye, M; Kober, F; Le Fur, Y; Nicoli, F, 2010) |
| "In order to confirm the roles of creatine (Cr) in epilepsy, we investigated the anti-convulsive effects of Cr, creatine transporter (CRT) and creatine kinases (CKs) against chemical-induced acute seizure activity and chronic epileptic seizure activity." | 3.76 | Effects of creatine and β-guanidinopropionic acid and alterations in creatine transporter and creatine kinases expression in acute seizure and chronic epilepsy models. ( Choi, SY; Kang, TC; Kim, DW; Kim, JE; Kwon, OS; Ryu, HJ; Song, HK; Yeo, SI, 2010) |
| "Disorders of creatine synthesis or its transporter resulting in neurological impairment with mental retardation and epilepsy have only been recognized in recent years." | 3.74 | Severe epilepsy in X-linked creatine transporter defect (CRTR-D). ( Baglietto, MG; Battaglia, FM; Caruso, U; Gaggero, R; Jakobs, C; Mancardi, MM; Rossi, A; Salomons, GS; Schiaffino, MC; Veneselli, E; Zara, F, 2007) |
| "Vigabatrin (VGB) is a new antiepileptic drug that increases the human brain gamma-aminobutyric acid (GABA) level by irreversibly inhibiting GABA transaminase." | 2.70 | Effects of vigabatrin on brain GABA+/CR signals in patients with epilepsy monitored by 1H-NMR-spectroscopy: responder characteristics. ( Boesiger, P; Duc, CO; Meier, D; Mueller, SG; Russ, W; Weber, B; Weber, OM; Wieser, HG, 2001) |
| "Levetiracetam was generally well tolerated." | 2.70 | Pharmacokinetic study of levetiracetam in children. ( Bebin, EM; Coupez, RM; Fountain, NB; Glauser, TA; Pellock, JM; Ritter, FJ; Shields, WD, 2001) |
| "Epilepsy is one of the main symptoms in GAMT and CT1 deficiency, whereas the occurrence of febrile convulsions in infancy is a relatively common presenting symptom in all the three above-mentioned diseases." | 2.49 | Inborn errors of creatine metabolism and epilepsy. ( Battini, R; Cioni, G; Leuzzi, V; Mastrangelo, M, 2013) |
| "Epilepsy is often considered to be a progressive neurological disease, and the nature of this progression remains unclear." | 1.72 | Insights into the development of pentylenetetrazole-induced epileptic seizures from dynamic metabolomic changes. ( Cheng, P; Jia, P; Liao, S; Meng, K; Xiao, C; Xu, R; Zhao, X; Zheng, X, 2022) |
| "Semiology, seizure frequency, and therapy were assessed for all patients." | 1.46 | Proton MR Spectroscopy in Patients With Sleep-Related Hypermotor Epilepsy (SHE): Evidence of Altered Cingulate Cortex Metabolism. ( Bisulli, F; Ferri, L; Gramegna, LL; Licchetta, L; Lodi, R; Naldi, I; Rizzo, G; Testa, C; Tinuper, P; Tonon, C, 2017) |
| "We present a case of infantile onset Krabbe disease with prolonged survival, initial intracranial optic nerves and optic chiasm hypertrophy, and serial changes on cranial magnetic resonance imaging and magnetic resonance spectroscopy." | 1.38 | Prolonged survival and serial magnetic resonance imaging/magnetic resonance spectroscopy changes in infantile Krabbe disease. ( Bunge, M; Mhanni, AA; Ryner, L; Salman, MS; Udow, S, 2012) |
| "Treatment with creatine monohydrate, to enhance cerebral creatine transport, combined with L-arginine and L-glycine, to enhance cerebral creatine synthesis, resulted in complete resolution of seizures." | 1.36 | Treatment of intractable epilepsy in a female with SLC6A8 deficiency. ( Casey, B; Connolly, MB; Davis, C; Horvath, GA; Jakobs, C; Lowry, N; Mercimek-Mahmutoglu, S; Poskitt, KJ; Salomons, GS; Sinclair, G; Stockler-Ipsiroglu, S, 2010) |
| "Intracranial arachnoid cysts (ACs) are usually asymptomatic, benign developmental anomalies." | 1.35 | Single-voxel magnetic resonance spectroscopy of brain tissue adjacent to arachnoid cysts of epileptic patients. ( Ozcan, C; Ozisik, HI; Sarac, K, 2008) |
| "These data argue that within the seizure onset zone, the tight correlation between total power and NAA/Cr suggests that total electrical output is powered by available mitochondrial function." | 1.35 | Intracranial EEG power and metabolism in human epilepsy. ( Hetherington, HP; Pan, JW; Spencer, DD; Spencer, SS; Zaveri, HP, 2009) |
| "Although epilepsy was not affected by orally administered creatine (400 to 500 mg/kg per day), this treatment resulted in clinical improvement and an increase of creatine in cerebrospinal fluid and brain tissue." | 1.30 | Creatine deficiency syndrome caused by guanidinoacetate methyltransferase deficiency: diagnostic tools for a new inborn error of metabolism. ( Bachert, P; Bremer, HJ; De Deyn, PP; Hess, T; Knopp, MV; Marescau, B; Mayatepek, E; Rating, D; Schulze, A; Wevers, R, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (3.39) | 18.7374 |
| 1990's | 5 (8.47) | 18.2507 |
| 2000's | 26 (44.07) | 29.6817 |
| 2010's | 22 (37.29) | 24.3611 |
| 2020's | 4 (6.78) | 2.80 |
| Authors | Studies |
|---|---|
| Hashiguchi, M | 1 |
| Tanaka, K | 1 |
| Nagashima, H | 1 |
| Fujita, Y | 1 |
| Tanaka, H | 1 |
| Kohta, M | 1 |
| Nakai, T | 1 |
| Uozumi, Y | 1 |
| Maeyama, M | 1 |
| Somiya, Y | 1 |
| Kohmura, E | 1 |
| Sasayama, T | 1 |
| Zhao, X | 1 |
| Cheng, P | 1 |
| Xu, R | 1 |
| Meng, K | 1 |
| Liao, S | 1 |
| Jia, P | 1 |
| Zheng, X | 1 |
| Xiao, C | 1 |
| Sun, WH | 1 |
| Zhuang, DY | 1 |
| Wang, Y | 1 |
| Xiao, FF | 1 |
| Wu, MY | 1 |
| Dong, XR | 1 |
| Zhang, P | 1 |
| Wang, HJ | 1 |
| Zhou, WH | 1 |
| Wu, BB | 1 |
| Cacciante, F | 1 |
| Gennaro, M | 1 |
| Sagona, G | 1 |
| Mazziotti, R | 1 |
| Lupori, L | 1 |
| Cerri, E | 1 |
| Putignano, E | 1 |
| Butt, M | 1 |
| Do, MT | 1 |
| McKew, JC | 1 |
| Alessandrì, MG | 1 |
| Battini, R | 2 |
| Cioni, G | 3 |
| Pizzorusso, T | 1 |
| Baroncelli, L | 1 |
| Lopez-Marin, L | 1 |
| Wu, HC | 1 |
| Dachet, F | 1 |
| Ghoddoussi, F | 1 |
| Bagla, S | 1 |
| Fuerst, D | 1 |
| Stanley, JA | 1 |
| Galloway, MP | 1 |
| Loeb, JA | 1 |
| Naldi, I | 1 |
| Bisulli, F | 1 |
| Testa, C | 1 |
| Rizzo, G | 1 |
| Ferri, L | 1 |
| Gramegna, LL | 1 |
| Licchetta, L | 1 |
| Lodi, R | 1 |
| Tonon, C | 1 |
| Tinuper, P | 1 |
| Hall, J | 1 |
| Frenguelli, BG | 1 |
| Barta, H | 1 |
| Jermendy, A | 1 |
| Kolossvary, M | 1 |
| Kozak, LR | 1 |
| Lakatos, A | 1 |
| Meder, U | 1 |
| Szabo, M | 1 |
| Rudas, G | 1 |
| Peng, WF | 1 |
| Ding, J | 1 |
| Mao, LY | 1 |
| Li, X | 1 |
| Liang, L | 1 |
| Chen, CZ | 1 |
| Cheng, WZ | 1 |
| Fan, W | 1 |
| Wang, X | 1 |
| Reid, CA | 1 |
| Mullen, S | 1 |
| Kim, TH | 1 |
| Petrou, S | 1 |
| Eldin, EE | 1 |
| Elshebiny, HA | 1 |
| Mohamed, TM | 1 |
| Abdel-Aziz, MA | 1 |
| El-Readi, MZ | 1 |
| Nozaki, F | 1 |
| Kumada, T | 1 |
| Shibata, M | 1 |
| Fujii, T | 1 |
| Wada, T | 1 |
| Osaka, H | 1 |
| Tschampa, HJ | 1 |
| Urbach, H | 1 |
| Träber, F | 1 |
| Sprinkart, AM | 1 |
| Greschus, S | 1 |
| Malter, MP | 1 |
| Surges, R | 1 |
| Gieseke, J | 1 |
| Block, W | 1 |
| Juhász, C | 1 |
| Hu, J | 1 |
| Xuan, Y | 1 |
| Chugani, HT | 1 |
| Romariz, SA | 1 |
| Paiva, DS | 1 |
| Galindo, LT | 1 |
| Barnabé, GF | 1 |
| Guedes, VA | 1 |
| Borlongan, CV | 1 |
| Longo, BM | 1 |
| Stern, WM | 1 |
| Winston, JS | 1 |
| Murphy, E | 1 |
| Cross, JH | 1 |
| Sander, JW | 1 |
| Fons, C | 2 |
| Sempere, A | 2 |
| Arias, A | 2 |
| López-Sala, A | 1 |
| Póo, P | 2 |
| Pineda, M | 2 |
| Mas, A | 1 |
| Vilaseca, MA | 2 |
| Salomons, GS | 5 |
| Ribes, A | 2 |
| Artuch, R | 2 |
| Campistol, J | 2 |
| Ozisik, HI | 1 |
| Sarac, K | 1 |
| Ozcan, C | 1 |
| Valayannopoulos, V | 1 |
| Boddaert, N | 1 |
| Mention, K | 1 |
| Touati, G | 1 |
| Barbier, V | 1 |
| Chabli, A | 1 |
| Sedel, F | 1 |
| Kaplan, J | 1 |
| Dufier, JL | 1 |
| Seidenwurm, D | 1 |
| Rabier, D | 1 |
| Saudubray, JM | 1 |
| de Lonlay, P | 1 |
| Pan, JW | 2 |
| Zaveri, HP | 1 |
| Spencer, DD | 2 |
| Hetherington, HP | 2 |
| Spencer, SS | 1 |
| Sanmartí, FX | 1 |
| Merinero, B | 1 |
| Le Fur, Y | 1 |
| Nicoli, F | 1 |
| Guye, M | 1 |
| Confort-Gouny, S | 1 |
| Cozzone, PJ | 1 |
| Kober, F | 1 |
| Nasrallah, F | 1 |
| Feki, M | 1 |
| Kaabachi, N | 1 |
| Mercimek-Mahmutoglu, S | 2 |
| Connolly, MB | 1 |
| Poskitt, KJ | 1 |
| Horvath, GA | 1 |
| Lowry, N | 1 |
| Casey, B | 1 |
| Sinclair, G | 1 |
| Davis, C | 1 |
| Jakobs, C | 4 |
| Stockler-Ipsiroglu, S | 2 |
| Kim, DW | 1 |
| Yeo, SI | 1 |
| Ryu, HJ | 1 |
| Kim, JE | 1 |
| Song, HK | 1 |
| Kwon, OS | 1 |
| Choi, SY | 1 |
| Kang, TC | 1 |
| Striano, P | 1 |
| Morana, G | 1 |
| Pezzella, M | 1 |
| Bellini, T | 1 |
| Rossi, A | 2 |
| Saraiva, AL | 1 |
| Ferreira, AP | 1 |
| Silva, LF | 1 |
| Hoffmann, MS | 1 |
| Dutra, FD | 1 |
| Furian, AF | 1 |
| Oliveira, MS | 1 |
| Fighera, MR | 1 |
| Royes, LF | 1 |
| Lee, EM | 1 |
| Park, GY | 1 |
| Im, KC | 1 |
| Kim, ST | 1 |
| Woo, CW | 1 |
| Chung, JH | 1 |
| Kim, KS | 1 |
| Kim, JS | 1 |
| Shon, YM | 1 |
| Kim, YI | 1 |
| Kang, JK | 1 |
| Udow, S | 1 |
| Bunge, M | 1 |
| Ryner, L | 1 |
| Mhanni, AA | 1 |
| Salman, MS | 1 |
| Leuzzi, V | 4 |
| Mastrangelo, M | 1 |
| Ziyeh, S | 1 |
| Thiel, T | 1 |
| Spreer, J | 1 |
| Klisch, J | 1 |
| Schumacher, M | 1 |
| Chang, L | 1 |
| Cloak, CC | 1 |
| Ernst, T | 1 |
| Kim, JH | 1 |
| Mueller, SG | 4 |
| D Laxer, K | 1 |
| Barakos, JA | 2 |
| Cashdollar, N | 3 |
| Flenniken, DL | 2 |
| Vermathen, P | 2 |
| Matson, GB | 2 |
| Weiner, MW | 4 |
| Shirayama, Y | 1 |
| Takahashi, S | 1 |
| Minabe, Y | 1 |
| Ogino, T | 1 |
| Briellmann, RS | 1 |
| Wellard, RM | 1 |
| Jackson, GD | 1 |
| Laxer, KD | 2 |
| Lopez, RC | 1 |
| Schuff, N | 1 |
| Meyerhoff, DJ | 1 |
| Mueller, S | 1 |
| Chao, L | 1 |
| Sacrey, DT | 1 |
| Laxer, K | 1 |
| Stoeckler-Ipsiroglu, S | 1 |
| Adami, A | 1 |
| Appleton, R | 1 |
| Araújo, HC | 1 |
| Duran, M | 1 |
| Ensenauer, R | 1 |
| Fernandez-Alvarez, E | 1 |
| Garcia, P | 1 |
| Grolik, C | 1 |
| Item, CB | 1 |
| Marquardt, I | 1 |
| Mühl, A | 1 |
| Saelke-Kellermann, RA | 1 |
| Schulze, A | 2 |
| Surtees, R | 1 |
| van der Knaap, MS | 2 |
| Vasconcelos, R | 1 |
| Verhoeven, NM | 2 |
| Vilarinho, L | 1 |
| Wilichowski, E | 1 |
| Mancardi, MM | 1 |
| Caruso, U | 1 |
| Schiaffino, MC | 1 |
| Baglietto, MG | 1 |
| Battaglia, FM | 1 |
| Zara, F | 1 |
| Veneselli, E | 1 |
| Gaggero, R | 1 |
| Yapici, Z | 1 |
| Dörtcan, N | 1 |
| Baykan, BB | 1 |
| Okan, F | 1 |
| Dinçer, A | 1 |
| Baykal, C | 1 |
| Eraksoy, M | 1 |
| Roach, S | 1 |
| Hiremath, GK | 1 |
| Najm, IM | 1 |
| Hojo, Y | 1 |
| Breiter, SN | 1 |
| Arroyo, S | 1 |
| Mathews, VP | 1 |
| Lesser, RP | 1 |
| Bryan, RN | 1 |
| Barker, PB | 1 |
| Gadian, DG | 1 |
| Kuzniecky, R | 1 |
| Hetherington, H | 1 |
| Pan, J | 1 |
| Hugg, J | 1 |
| Palmer, C | 1 |
| Gilliam, F | 1 |
| Faught, E | 1 |
| Morawetz, R | 1 |
| Hess, T | 1 |
| Wevers, R | 1 |
| Mayatepek, E | 1 |
| Bachert, P | 1 |
| Marescau, B | 1 |
| Knopp, MV | 1 |
| De Deyn, PP | 1 |
| Bremer, HJ | 1 |
| Rating, D | 1 |
| Maaswinkel-Mooij, P | 1 |
| Pouwels, PJ | 1 |
| Onkenhout, W | 1 |
| Peeters, EA | 1 |
| McLean, MA | 2 |
| Woermann, FG | 2 |
| Barker, GJ | 2 |
| Duncan, JS | 2 |
| Mizuno, S | 1 |
| Takahashi, Y | 1 |
| Kato, Z | 1 |
| Goto, H | 1 |
| Kondo, N | 1 |
| Hoshi, H | 1 |
| Bianchi, MC | 1 |
| Tosetti, M | 1 |
| Carducci, C | 1 |
| Cerquiglini, CA | 1 |
| Antonozzi, I | 1 |
| Bartlett, PA | 1 |
| Weber, OM | 1 |
| Duc, CO | 1 |
| Weber, B | 1 |
| Meier, D | 1 |
| Russ, W | 1 |
| Boesiger, P | 1 |
| Wieser, HG | 1 |
| Pellock, JM | 1 |
| Glauser, TA | 1 |
| Bebin, EM | 1 |
| Fountain, NB | 1 |
| Ritter, FJ | 1 |
| Coupez, RM | 1 |
| Shields, WD | 1 |
| Peeling, J | 1 |
| Sutherland, G | 1 |
| Berlet, HH | 1 |
| Pilz, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Remote Effects of Stroke on Cerebral Metabolism. Evaluation With Positron Emission Tomography and Proton Magnetic Resonance Spectroscopy[NCT00063180] | 70 participants | Observational | 2003-06-19 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for creatine and Aura
| Article | Year |
|---|---|
[Metabolic approach in epileptic encephalopathies in infants].
Topics: Age of Onset; Biotin; Brain Diseases, Metabolic; Brain Diseases, Metabolic, Inborn; Child, Preschool | 2017 |
Epilepsy, energy deficiency and new therapeutic approaches including diet.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Astrocytes; Creatine; Diet, Ketogenic; Energy Int | 2014 |
Creatine and creatine deficiency syndromes: biochemical and clinical aspects.
Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Autistic Disorder; Child; Creatine; Epile | 2010 |
Inborn errors of creatine metabolism and epilepsy.
Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic, Inbor | 2013 |
Inborn errors of creatine metabolism and epilepsy: clinical features, diagnosis, and treatment.
Topics: Amidinotransferases; Brain; Child; Clinical Laboratory Techniques; Creatine; Electroencephalography; | 2002 |
Magnetic resonance spectroscopy studies of GABA in neuropsychiatric disorders.
Topics: Anxiety Disorders; Brain; Brain Chemistry; Creatine; Depressive Disorder; Epilepsy; GABA Agents; gam | 2003 |
Seizure-associated abnormalities in epilepsy: evidence from MR imaging.
Topics: Adult; Aspartic Acid; Atrophy; Brain; Brain Diseases; Brain Edema; Choline; Creatine; Diffusion Magn | 2005 |
N-acetylaspartate as a marker of neuronal injury in neurodegenerative disease.
Topics: Aging; Alcoholism; Amyotrophic Lateral Sclerosis; Aspartic Acid; Biomarkers; Brain; Brain Injuries; | 2006 |
Magnetic resonance spectroscopy in animal models of epilepsy.
Topics: Animals; Aspartic Acid; Brain; Carbon Isotopes; Choline; Creatine; Disease Models, Animal; Epilepsy; | 2007 |
4 trials available for creatine and Aura
| Article | Year |
|---|---|
Quantitative analysis of short echo time (1)H-MRSI of cerebral gray and white matter.
Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Calibration; Cerebrospinal Fluid; Choline; Creatine; D | 2000 |
Quantitative short echo time proton magnetic resonance spectroscopic imaging study of malformations of cortical development causing epilepsy.
Topics: Adult; Analysis of Variance; Aspartic Acid; Cerebral Cortex; Choline; Creatine; Dipeptides; Epilepsy | 2001 |
Effects of vigabatrin on brain GABA+/CR signals in patients with epilepsy monitored by 1H-NMR-spectroscopy: responder characteristics.
Topics: Adolescent; Adult; Anticonvulsants; Brain; Brain Chemistry; Carnosine; Creatine; Epilepsy; Epilepsy, | 2001 |
Pharmacokinetic study of levetiracetam in children.
Topics: Adult; Age Factors; Anticonvulsants; Child; Creatine; Epilepsy; Female; Humans; Levetiracetam; Male; | 2001 |
46 other studies available for creatine and Aura
| Article | Year |
|---|---|
Glutamic Acid and Total Creatine as Predictive Markers for Epilepsy in Glioblastoma by Using Magnetic Resonance Spectroscopy Before Surgery.
Topics: Creatine; Epilepsy; Glioblastoma; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magn | 2022 |
Insights into the development of pentylenetetrazole-induced epileptic seizures from dynamic metabolomic changes.
Topics: Alanine; Animals; Anticonvulsants; Asparagine; Citrates; Creatine; Creatinine; Disease Models, Anima | 2022 |
[Clinical features and SLC6A8 gene mutations of cerebral creatine deficiency syndrome I: an analysis of two families].
Topics: Child; Child, Preschool; Creatine; Epilepsy; Genetic Testing; Humans; Male; Mutation; Nerve Tissue P | 2020 |
Cyclocreatine treatment ameliorates the cognitive, autistic and epileptic phenotype in a mouse model of Creatine Transporter Deficiency.
Topics: Animals; Autistic Disorder; Blood-Brain Barrier; Brain Diseases, Metabolic, Inborn; Cerebrovascular | 2020 |
Altered metabolomic-genomic signature: A potential noninvasive biomarker of epilepsy.
Topics: Adolescent; Biomarkers; Brain; Child; Child, Preschool; Choline; Creatine; Epilepsy; Female; Genetic | 2017 |
Proton MR Spectroscopy in Patients With Sleep-Related Hypermotor Epilepsy (SHE): Evidence of Altered Cingulate Cortex Metabolism.
Topics: Adult; Aspartic Acid; Case-Control Studies; Creatine; Epilepsy; Female; Gyrus Cinguli; Humans; Magne | 2017 |
The combination of ribose and adenine promotes adenosine release and attenuates the intensity and frequency of epileptiform activity in hippocampal slices: Evidence for the rapid depletion of cellular ATP during electrographic seizures.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Creatine; Electrophysiological Phenomena; Epile | 2018 |
Prognostic value of early, conventional proton magnetic resonance spectroscopy in cooled asphyxiated infants.
Topics: Aspartic Acid; Brain; Creatine; Epilepsy; Female; Hearing Loss; Hospital Mortality; Humans; Hypother | 2018 |
Increased ratio of glutamate/glutamine to creatine in the right hippocampus contributes to depressive symptoms in patients with epilepsy.
Topics: Adolescent; Adult; Creatine; Depression; Epilepsy; Female; Functional Laterality; Glutamic Acid; Glu | 2013 |
The role of antiepileptic drugs in free radicals generation and antioxidant levels in epileptic patients.
Topics: Adolescent; Adult; Anticonvulsants; Antioxidants; Child; Creatine; Epilepsy; Female; Follow-Up Studi | 2016 |
[A family with creatine transporter deficiency diagnosed with urinary creatine/creatinine ratio and the family history: the third Japanese familial case].
Topics: Adolescent; Brain Diseases, Metabolic, Inborn; Child; Creatine; Creatinine; Epilepsy; Female; Humans | 2015 |
Proton magnetic resonance spectroscopy in focal cortical dysplasia at 3T.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Child, Preschool; Choline; Creatine; Drug Resistant E | 2015 |
Imaging increased glutamate in children with Sturge-Weber syndrome: Association with epilepsy severity.
Topics: Aspartic Acid; Brain; Child; Child, Preschool; Creatine; Epilepsy; Female; Fluorodeoxyglucose F18; F | 2016 |
Medial Ganglionic Eminence Cells Freshly Obtained or Expanded as Neurospheres Show Distinct Cellular and Molecular Properties in Reducing Epileptic Seizures.
Topics: Animals; Cell Differentiation; Cells, Cultured; Creatine; Disease Models, Animal; Embryo, Mammalian; | 2017 |
Guanidinoacetate methyltransferase (GAMT) deficiency: a rare but treatable epilepsy.
Topics: Adult; Creatine; Epilepsy; Guanidinoacetate N-Methyltransferase; Humans; Language Development Disord | 2017 |
Arginine supplementation in four patients with X-linked creatine transporter defect.
Topics: Administration, Oral; Adolescent; Age of Onset; Arginine; Child; Chromosomes, Human, X; Creatine; Di | 2008 |
Single-voxel magnetic resonance spectroscopy of brain tissue adjacent to arachnoid cysts of epileptic patients.
Topics: Adolescent; Adult; Arachnoid Cysts; Aspartic Acid; Brain; Brain Mapping; Child; Choline; Creatine; E | 2008 |
Secondary creatine deficiency in ornithine delta-aminotransferase deficiency.
Topics: Adolescent; Adult; Aggression; Apraxias; Brain; Child; Creatine; Epilepsy; Female; Gyrate Atrophy; H | 2009 |
Intracranial EEG power and metabolism in human epilepsy.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Creatine; Electrodes, Implanted; Electroencephalography; En | 2009 |
Epilepsy spectrum in cerebral creatine transporter deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Brain; Child, Preschool; Creatine; Electroencephalography; Epi | 2009 |
Grid-free interactive and automated data processing for MR chemical shift imaging data.
Topics: Aspartic Acid; Brain; Brain Mapping; Brain Neoplasms; Case-Control Studies; Choline; Creatine; Elect | 2010 |
Treatment of intractable epilepsy in a female with SLC6A8 deficiency.
Topics: Arginine; Child; Creatine; Drug Therapy, Combination; Epilepsy; Female; Glycine; Heterozygote; Human | 2010 |
Effects of creatine and β-guanidinopropionic acid and alterations in creatine transporter and creatine kinases expression in acute seizure and chronic epilepsy models.
Topics: Acute Disease; Animals; CA1 Region, Hippocampal; Chronic Disease; Creatine; Creatine Kinase; Disease | 2010 |
Rhombencephalosynapsis in a patient with mental retardation, epilepsy, and dysmorphisms.
Topics: Adolescent; Aspartic Acid; Body Dysmorphic Disorders; Creatine; Epilepsy; Humans; Intellectual Disab | 2011 |
Creatine reduces oxidative stress markers but does not protect against seizure susceptibility after severe traumatic brain injury.
Topics: Animals; Brain Injuries; Creatine; Dietary Supplements; Disease Models, Animal; Electroencephalograp | 2012 |
Changes in glucose metabolism and metabolites during the epileptogenic process in the lithium-pilocarpine model of epilepsy.
Topics: Animals; Aspartic Acid; Brain Mapping; Choline; Creatine; Disease Models, Animal; Epilepsy; Fluorode | 2012 |
Prolonged survival and serial magnetic resonance imaging/magnetic resonance spectroscopy changes in infantile Krabbe disease.
Topics: Anticonvulsants; Aspartic Acid; Brain Chemistry; Choline; Combined Modality Therapy; Creatine; DNA M | 2012 |
Valproate-induced encephalopathy: assessment with MR imaging and 1H MR spectroscopy.
Topics: Adult; Anticonvulsants; Aspartic Acid; Brain; Brain Diseases, Metabolic; Choline; Creatine; Epilepsy | 2002 |
1H and 31P spectroscopic imaging of epilepsy: spectroscopic and histologic correlations.
Topics: Adult; Amygdala; Aspartic Acid; Brain; Choline; Creatine; Epilepsy; Epilepsy, Temporal Lobe; Female; | 2004 |
Identification of the epileptogenic lobe in neocortical epilepsy with proton MR spectroscopic imaging.
Topics: Adolescent; Adult; Aspartic Acid; Brain Mapping; Choline; Creatine; Electroencephalography; Epilepsi | 2004 |
In vitro 1H NMR spectroscopy shows an increase in N-acetylaspartylglutamate and glutamine content in the hippocampus of amygdaloid-kindled rats.
Topics: Amino Acids; Amygdala; Animals; Creatine; Dipeptides; Disease Models, Animal; Energy Metabolism; Epi | 2005 |
Metabolic characteristics of cortical malformations causing epilepsy.
Topics: Adolescent; Adult; Aspartic Acid; Cerebral Cortex; Choline; Creatine; Epilepsy; Humans; Image Proces | 2005 |
Spectroscopic evidence of hippocampal abnormalities in neocortical epilepsy.
Topics: Adolescent; Adult; Aspartic Acid; Choline; Creatine; Epilepsy; Female; Functional Laterality; Hippoc | 2006 |
GAMT deficiency: features, treatment, and outcome in an inborn error of creatine synthesis.
Topics: Adolescent; Adult; Child; Creatine; Epilepsy; Female; Glycine; Guanidinoacetate N-Methyltransferase; | 2006 |
Severe epilepsy in X-linked creatine transporter defect (CRTR-D).
Topics: Anticonvulsants; Brain; Child, Preschool; Creatine; Electroencephalography; Epilepsy; Genes, X-Linke | 2007 |
Neurological aspects of tuberous sclerosis in relation to MRI/MR spectroscopy findings in children with epilepsy.
Topics: Adolescent; Aspartic Acid; Child; Child, Preschool; Creatine; Epilepsy; Female; Humans; Infant; Magn | 2007 |
Subject groups high and low in urinary selenium levels: workers exposed to heavy metals and patients with cancer and epilepsy.
Topics: Creatine; Environmental Exposure; Epilepsy; Humans; Industry; Metals; Neoplasms; Selenium | 1981 |
Proton MR spectroscopy in patients with seizure disorders.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Cerebral Cortex; Child; Child, Preschool; Choline; Creatine | 1994 |
N-acetylaspartate and epilepsy.
Topics: Adult; Aspartic Acid; Brain Damage, Chronic; Brain Mapping; Child; Choline; Creatine; Dominance, Cer | 1995 |
Proton spectroscopic imaging at 4.1 tesla in patients with malformations of cortical development and epilepsy.
Topics: Acetylation; Adolescent; Adult; Brain; Brain Neoplasms; Cerebral Cortex; Choline; Choristoma; Creati | 1997 |
Creatine deficiency syndrome caused by guanidinoacetate methyltransferase deficiency: diagnostic tools for a new inborn error of metabolism.
Topics: Amino Acid Metabolism, Inborn Errors; Brain; Cells, Cultured; Child, Preschool; Creatine; Creatinine | 1997 |
Mental retardation and behavioral problems as presenting signs of a creatine synthesis defect.
Topics: Aspartic Acid; Body Fluids; Brain Diseases, Metabolic; Child, Preschool; Creatine; Diagnosis, Differ | 2000 |
Magnetic resonance spectroscopy of tubers in patients with tuberous sclerosis.
Topics: Adult; Age Factors; Aspartic Acid; Case-Control Studies; Child; Child, Preschool; Creatine; Disease | 2000 |
Brain creatine depletion: guanidinoacetate methyltransferase deficiency (improving with creatine supplementation).
Topics: Brain Chemistry; Child, Preschool; Creatine; Epilepsy; Guanidinoacetate N-Methyltransferase; Humans; | 2000 |
High-resolution 1H NMR spectroscopy studies of extracts of human cerebral neoplasms.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Amino Acids; Astrocytoma; Brain; Brain Neoplasm | 1992 |
[Significance of plasma creatine and neurologic disorders for the creatine level of cerebrospinal fluid in man].
Topics: Amyotrophic Lateral Sclerosis; Creatine; Dementia; Encephalitis; Epilepsy; Humans; Meningitis; Multi | 1972 |