Page last updated: 2024-10-17

creatine and Amphetamine-Related Disorders

creatine has been researched along with Amphetamine-Related Disorders in 9 studies

Amphetamine-Related Disorders: Disorders related or resulting from use of amphetamines.

Research Excerpts

ExcerptRelevanceReference
"Methamphetamine abuse is associated with neurotoxicity to frontostriatal brain regions with concomitant deleterious effects on cognitive processes."7.74Attentional control and brain metabolite levels in methamphetamine abusers. ( Buonocore, MH; Galloway, GP; Leamon, MH; Moore, CD; Natsuaki, Y; Nordahl, TE; Salo, R; Waters, C, 2007)
"Methamphetamine abuse is associated with neurotoxicity to frontostriatal brain regions with concomitant deleterious effects on cognitive processes."3.74Attentional control and brain metabolite levels in methamphetamine abusers. ( Buonocore, MH; Galloway, GP; Leamon, MH; Moore, CD; Natsuaki, Y; Nordahl, TE; Salo, R; Waters, C, 2007)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (55.56)29.6817
2010's4 (44.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burger, A1
Brooks, SJ1
Stein, DJ1
Howells, FM1
Hellem, TL1
Sung, YH2
Shi, XF1
Pett, MA1
Latendresse, G1
Morgan, J1
Huber, RS1
Kuykendall, D1
Lundberg, KJ1
Renshaw, PF2
Salo, R5
Buonocore, MH4
Leamon, M2
Natsuaki, Y3
Waters, C4
Moore, CD4
Galloway, GP4
Nordahl, TE5
Natsuaki, YT1
Leamon, MH2
Possin, K1
Gibson, DR1
Flynn, N1
Pfefferbaum, A1
Spielman, DM1
Adalsteinsson, E1
Sullivan, EV1
Chang, L1
Ernst, T1
Speck, O1
Grob, CS1
Kile, S1
Cho, SC1
Hwang, J1
Kim, SJ1
Kim, H1
Bae, S1
Kim, N1
Chang, KH1
Daniels, M1
Lyoo, IK1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Creatine as a Treatment Option for Depression in Methamphetamine Using Females[NCT01514630]Phase 414 participants (Actual)Interventional2013-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

HAMD Rating Scores

"Eight weeks of oral creatine supplementation will result in improvements in Hamilton Depression Rating Scale (HAMD) in female methamphetamine users. HAMD scoring is based on 17 items. Minimum score is 0 and maximum 52. A score of 0-7 is considered to be normal. Scores of 20 or higher indicate moderate or severe depression.~0-7 = Normal 8-13 = Mild Depression 14-18 = Moderate Depression 19-22 = Severe Depression~≥ 23 = Very Severe Depression" (NCT01514630)
Timeframe: Over the course of eight weeks. Depression rating scores will be measured weekly for eight weeks for each subject enrolled.

InterventionUnits on a scale (Mean)
Baselineweek 2week 3week 4week 5week 6week 7week 8
Creatine Monohydrate16.8610.719.817.338.357.736.287.36

Other Studies

9 other studies available for creatine and Amphetamine-Related Disorders

ArticleYear
The impact of acute and short-term methamphetamine abstinence on brain metabolites: A proton magnetic resonance spectroscopy chemical shift imaging study.
    Drug and alcohol dependence, 2018, 04-01, Volume: 185

    Topics: Adolescent; Adult; Amphetamine-Related Disorders; Aspartic Acid; Brain; Choline; Creatine; Dipeptide

2018
Creatine as a Novel Treatment for Depression in Females Using Methamphetamine: A Pilot Study.
    Journal of dual diagnosis, 2015, Volume: 11, Issue:3-4

    Topics: Adult; Amphetamine-Related Disorders; Antidepressive Agents; Brain; Creatine; Depressive Disorder; D

2015
Extended findings of brain metabolite normalization in MA-dependent subjects across sustained abstinence: a proton MRS study.
    Drug and alcohol dependence, 2011, Jan-15, Volume: 113, Issue:2-3

    Topics: Adult; Amphetamine-Related Disorders; Aspartic Acid; Brain; Choline; Creatine; Female; Gyrus Cinguli

2011
Spatial inhibition and the visual cortex: a magnetic resonance spectroscopy imaging study.
    Neuropsychologia, 2011, Volume: 49, Issue:5

    Topics: Adult; Amphetamine-Related Disorders; Analysis of Variance; Aspartic Acid; Attention; Brain Mapping;

2011
Low N-acetyl-aspartate and high choline in the anterior cingulum of recently abstinent methamphetamine-dependent subjects: a preliminary proton MRS study. Magnetic resonance spectroscopy.
    Psychiatry research, 2002, Nov-30, Volume: 116, Issue:1-2

    Topics: Adult; Age Factors; Amphetamine-Related Disorders; Aspartic Acid; Choline; Creatine; Dopamine; Front

2002
Additive effects of HIV and chronic methamphetamine use on brain metabolite abnormalities.
    The American journal of psychiatry, 2005, Volume: 162, Issue:2

    Topics: Adult; Amphetamine-Related Disorders; Aspartic Acid; Basal Ganglia; Brain; Brain Diseases; Choline;

2005
Methamphetamine users in sustained abstinence: a proton magnetic resonance spectroscopy study.
    Archives of general psychiatry, 2005, Volume: 62, Issue:4

    Topics: Adult; Ambulatory Care; Amphetamine-Related Disorders; Aspartic Acid; Brain; Choline; Creatine; Dopa

2005
Relationship between N-acetyl-aspartate in gray and white matter of abstinent methamphetamine abusers and their history of drug abuse: a proton magnetic resonance spectroscopy study.
    Drug and alcohol dependence, 2007, Apr-17, Volume: 88, Issue:1

    Topics: Adult; Amphetamine-Related Disorders; Analysis of Variance; Aspartic Acid; Basal Ganglia; Choline; C

2007
Attentional control and brain metabolite levels in methamphetamine abusers.
    Biological psychiatry, 2007, Jun-01, Volume: 61, Issue:11

    Topics: Adult; Amphetamine-Related Disorders; Attention; Brain Chemistry; Central Nervous System Stimulants;

2007