creatine has been researched along with Aging in 213 studies
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Preexercise creatine supplementation may have a beneficial effect on aging muscle performance." | 9.22 | Effect of Preexercise Creatine Ingestion on Muscle Performance in Healthy Aging Males. ( Baker, TP; Candow, DG; Farthing, JP, 2016) |
| "To investigate the effects of creatine supplementation and drop-set resistance training in untrained aging adults." | 9.22 | Effect of creatine supplementation and drop-set resistance training in untrained aging adults. ( Brahms, CM; Candow, DG; Johannsmeyer, S; Michel, D; Zello, GA, 2016) |
| "The supplementation of creatine has shown a marked neuroprotective effect in mouse models of neurodegenerative diseases (Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis)." | 8.87 | Creatine in mouse models of neurodegeneration and aging. ( Bender, A; Elstner, M; Klopstock, T, 2011) |
| " However, there were no associations between NAA/Cr, Glu/Cr, or Gln/Cr and either depression severity or lamotrigine treatment." | 7.91 | Lamotrigine Therapy and Biomarkers of Cerebral Energy Metabolism in Older Age Bipolar Depression. ( Forester, BP; Harper, DG; Jensen, E; Mellen, EJ; Ravichandran, C; Silveri, M, 2019) |
| "Mutations in the creatine (Cr) transporter (CrT) gene lead to cerebral creatine deficiency syndrome-1 (CCDS1), an X-linked metabolic disorder characterized by cerebral Cr deficiency causing intellectual disability, seizures, movement and autistic-like behavioural disturbances, language and speech impairment." | 7.83 | A mouse model for creatine transporter deficiency reveals early onset cognitive impairment and neuropathology associated with brain aging. ( Alessandrì, MG; Baroncelli, L; Cacciante, F; Cioni, G; Leuzzi, V; Molinaro, A; Napoli, D; Pizzorusso, T; Putignano, E; Tola, J, 2016) |
| "To document trends and covariates of creatinemia (Scr) in extremely low birth weight (ELBW, < 1,000 g) neonates, maternal characteristics [betamethasone, premature preterm rupture of membranes (PPROM), pre-eclampsia, maternal Scr], characteristics at delivery [gestational age (GA), birth weight (BW), small for GA (SGA), Apgar, intubation] and during neonatal stay [ventilation, oxygen, parenteral nutrition, ibuprofen, steroids, intraventricular hemorrhage, retinopathy of prematurity (ROP), phototherapy] were linked with Scr observations." | 7.77 | Postnatal trends in creatinemia and its covariates in extremely low birth weight (ELBW) neonates. ( Allegaert, K; George, I; Levtchenko, E; Mekahli, D; Rayyan, M, 2011) |
| "Our objective was to investigate the influence of hypertension on N-acetylaspartate (NAA) and choline (Cho) ratios in brain tissues in a community-dwelling elderly population." | 7.74 | N-acetylaspartate/creatine and choline/creatine ratios in the thalami, insular cortex and white matter as markers of hypertension and cognitive impairment in the elderly. ( Aho, SL; Bejot, Y; Ben Salem, D; Brunotte, F; Ricolfi, F; Rouaud, O; Tavernier, B; Walker, PM, 2008) |
| "In order to establish the degree of renal malfunction necessary for colchicine toxicity in patients receiving it daily for the prevention of recurrent acute gout, we obtained serum creatinine levels and measured or estimated creatinine clearances in a consecutive series of 17 patients with demonstrated colchicine myotoxicity." | 7.68 | Renal function predicts colchicine toxicity: guidelines for the prophylactic use of colchicine in gout. ( Duncan, GJ; Kuncl, RW; Singer, JZ; Wallace, SL; Wigley, FM, 1991) |
| "Creatine is an endogenously produced metabolite, which has the theoretical potential to counteract many of the morphological and metabolic parameters underpinning sarcopenia." | 6.61 | Muscular Atrophy and Sarcopenia in the Elderly: Is There a Role for Creatine Supplementation? ( Artioli, GG; Dolan, E; Gualano, B; Pereira, RMR, 2019) |
| " Emerging evidence now suggests that the timing and dosage of creatine supplementation may be important factors for aging muscle accretion." | 6.47 | Sarcopenia: current theories and the potential beneficial effect of creatine application strategies. ( Candow, DG, 2011) |
| "This is an exploratory trial from the Pro-Elderly study ("Protein Intake and Resistance Training in Aging") aimed at gathering knowledge on the feasibility, safety, and efficacy of co-supplementation with creatine and protein supplementation, combined with resistance training, in older individuals with frailty." | 5.22 | Resistance Training and Co-supplementation with Creatine and Protein in Older Subjects with Frailty. ( Collins, J; Gualano, B; Longhurst, G; Roschel, H, 2016) |
| "Creatine supplementation in close proximity to resistance training may be an important strategy for increasing muscle mass and strength; however, it is unknown whether creatine supplementation before or after resistance training is more effective for aging adults." | 5.20 | Strategic creatine supplementation and resistance training in healthy older adults. ( Candow, DG; Farthing, JP; Forbes, SC; Johannsmeyer, S; Vogt, E, 2015) |
| "Creatine supplementation in conjunction with resistance training (RT) augments gains in lean tissue mass and strength in aging adults; however, there is a large amount of heterogeneity between individual studies that may be related to creatine ingestion strategies." | 5.12 | Meta-Analysis Examining the Importance of Creatine Ingestion Strategies on Lean Tissue Mass and Strength in Older Adults. ( Candow, DG; Chilibeck, PD; Forbes, SC; Ostojic, SM; Roberts, MD, 2021) |
| "The supplementation of creatine has shown a marked neuroprotective effect in mouse models of neurodegenerative diseases (Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis)." | 4.87 | Creatine in mouse models of neurodegeneration and aging. ( Bender, A; Elstner, M; Klopstock, T, 2011) |
| " However, there were no associations between NAA/Cr, Glu/Cr, or Gln/Cr and either depression severity or lamotrigine treatment." | 3.91 | Lamotrigine Therapy and Biomarkers of Cerebral Energy Metabolism in Older Age Bipolar Depression. ( Forester, BP; Harper, DG; Jensen, E; Mellen, EJ; Ravichandran, C; Silveri, M, 2019) |
| " Concentrations of glutamate + glutamin (Glx), cholin (Cho), myoinositol (mIns), N-acetyl aspartate (NAA) expressed as ratio with creatine (Cr) and NAA were correlated with markers of disease activity (RIO score), Multiple Sclerosis Severity Scale (MSSS), Depressive-Severity Status Scale and Simple Numerical Fatigue Scale." | 3.85 | Hypothalamic damage in multiple sclerosis correlates with disease activity, disability, depression, and fatigue. ( Baranovičová, E; Bittšanský, M; Čierny, D; Hnilicová, P; Kantorová, E; Kurča, E; Nosáľ, V; Poláček, H; Sivák, Š; Zeleňák, K, 2017) |
| "Mutations in the creatine (Cr) transporter (CrT) gene lead to cerebral creatine deficiency syndrome-1 (CCDS1), an X-linked metabolic disorder characterized by cerebral Cr deficiency causing intellectual disability, seizures, movement and autistic-like behavioural disturbances, language and speech impairment." | 3.83 | A mouse model for creatine transporter deficiency reveals early onset cognitive impairment and neuropathology associated with brain aging. ( Alessandrì, MG; Baroncelli, L; Cacciante, F; Cioni, G; Leuzzi, V; Molinaro, A; Napoli, D; Pizzorusso, T; Putignano, E; Tola, J, 2016) |
| "In a healthy aging normal population, choline/creatine and myo-inositol/creatine ratios were significantly increased in APOE E4 carriers, suggesting the presence of neuroinflammatory processes and greater membrane turnover in older carriers." | 3.80 | APOE genotype modulates proton magnetic resonance spectroscopy metabolites in the aging brain. ( Buthorn, JJ; Christen, E; Conejero-Goldberg, C; Davies, P; Dickinson, D; Goldberg, TE; Gomar, JJ; Gordon, ML; Huet, S; Keehlisen, L; Kingsley, PB; Koppel, J; Uluğ, AM, 2014) |
| "To document trends and covariates of creatinemia (Scr) in extremely low birth weight (ELBW, < 1,000 g) neonates, maternal characteristics [betamethasone, premature preterm rupture of membranes (PPROM), pre-eclampsia, maternal Scr], characteristics at delivery [gestational age (GA), birth weight (BW), small for GA (SGA), Apgar, intubation] and during neonatal stay [ventilation, oxygen, parenteral nutrition, ibuprofen, steroids, intraventricular hemorrhage, retinopathy of prematurity (ROP), phototherapy] were linked with Scr observations." | 3.77 | Postnatal trends in creatinemia and its covariates in extremely low birth weight (ELBW) neonates. ( Allegaert, K; George, I; Levtchenko, E; Mekahli, D; Rayyan, M, 2011) |
| " We used structural magnetic resonance imaging (sMRI) to measure the volume of the AHC, and magnetic resonance spectroscopy ((1)H-MRS) to measure concentrations of N-acetyl aspartate (NAA), creatine+phosphocreatine (Cr+PCr), myo-inositol (mI) and choline (Cho)." | 3.76 | Maturation of limbic regions in Asperger syndrome: a preliminary study using proton magnetic resonance spectroscopy and structural magnetic resonance imaging. ( Baird, G; Bolton, P; Conroy, RM; Curran, S; Daly, E; Foy, C; Hallahan, B; Murphy, DG; Murphy, KC; O'Brien, FM; O'Gorman, RL; Page, L; Robertson, D; Sharma, A, 2010) |
| "Our objective was to investigate the influence of hypertension on N-acetylaspartate (NAA) and choline (Cho) ratios in brain tissues in a community-dwelling elderly population." | 3.74 | N-acetylaspartate/creatine and choline/creatine ratios in the thalami, insular cortex and white matter as markers of hypertension and cognitive impairment in the elderly. ( Aho, SL; Bejot, Y; Ben Salem, D; Brunotte, F; Ricolfi, F; Rouaud, O; Tavernier, B; Walker, PM, 2008) |
| "Long- and short-echo proton spectroscopic imaging were used to investigate concentrations and R2 relaxation rates of N-acetyl aspartate (NAA) + N-acetyl aspartyl glutamate (NAAG), choline (Cho), creatine (Cr), and myoinositol (mI) in the white matter of the centrum semiovale of 106 healthy volunteers aged 50-90 years; usable data were obtained from 79 subjects." | 3.74 | Long and short echo time proton magnetic resonance spectroscopic imaging of the healthy aging brain. ( Charlton, RA; Howe, FA; Markus, HS; McIntyre, DJ, 2007) |
| "To assess the effect of aging on the proportions of choline (Cho), creatine, and N-acetylaspartate (NAA) in the brains of elderly women and men." | 3.72 | Brain changes with aging: MR spectroscopy at supraventricular plane shows differences between women and men. ( Breteler, MM; den Heijer, T; Hofman, A; Origgi, D; Oudkerk, M; Sijens, PE; Vermeer, SE, 2003) |
| " In megacolon the following occur: 1) structural remodeling expressed as a greater increase in the fraction of maximum force production at short lengths, a shift of optimum length (Lo) to longer lengths, and no change in force per square centimeter; 2) hypertrophy and hyperplasia of both circular and longitudinal muscle; 3) high resting compliance consistent with no disproportionate change in collagen or elastin composition; 4) marked distension so that in situ circumference approximately 1." | 3.69 | Hypertrophy of colonic smooth muscle: structural remodeling, chemical composition, and force output. ( Butler, TM; Mooers, SU; Narayan, S; Siegman, MJ; Starcher, BC; Stirewalt, WS; Trinkle-Mulcahy, L, 1997) |
| " In living adult rhesus monkeys, we studied the long-term effects of early mesial temporo-limbic (MTL) lesions on prefrontal cortex (PFC) neurons using proton magnetic resonance spectroscopic imaging (1H-MRSI), an in vivo neurochemical assay technique for measuring signals from metabolites such as N-acetyl-aspartate (NAA, a neuronal marker), choline-containing compounds (CHO) and creatine + phosphocreatine (CRE)." | 3.69 | Altered development of prefrontal neurons in rhesus monkeys with neonatal mesial temporo-limbic lesions: a proton magnetic resonance spectroscopic imaging study. ( Bachevalier, J; Bertolino, A; Frank, JA; Mattay, VS; Saunders, RC; Weinberger, DR, 1997) |
| "In order to establish the degree of renal malfunction necessary for colchicine toxicity in patients receiving it daily for the prevention of recurrent acute gout, we obtained serum creatinine levels and measured or estimated creatinine clearances in a consecutive series of 17 patients with demonstrated colchicine myotoxicity." | 3.68 | Renal function predicts colchicine toxicity: guidelines for the prophylactic use of colchicine in gout. ( Duncan, GJ; Kuncl, RW; Singer, JZ; Wallace, SL; Wigley, FM, 1991) |
| "Creatine has emerged as a promising neuroprotective agent." | 2.72 | Assessing Creatine Supplementation for Neuroprotection against Perinatal Hypoxic-Ischaemic Encephalopathy: A Systematic Review of Perinatal and Adult Pre-Clinical Studies. ( Ellery, SJ; Galinsky, R; Kelly, SB; Snow, RJ; Tran, NT; Walker, DW, 2021) |
| "Three patients developed renal failure." | 2.71 | Long-term outcome of adding mycophenolate mofetil to tacrolimus for nephrotoxicity following liver transplantation. ( Eghtesad, B; Fung, J; Gadomski, M; Jain, A; Marcos, A; Mohanka, R; Vekatramanan, R, 2005) |
| "Creatine is an endogenously produced metabolite, which has the theoretical potential to counteract many of the morphological and metabolic parameters underpinning sarcopenia." | 2.61 | Muscular Atrophy and Sarcopenia in the Elderly: Is There a Role for Creatine Supplementation? ( Artioli, GG; Dolan, E; Gualano, B; Pereira, RMR, 2019) |
| " Emerging evidence now suggests that the timing and dosage of creatine supplementation may be important factors for aging muscle accretion." | 2.47 | Sarcopenia: current theories and the potential beneficial effect of creatine application strategies. ( Candow, DG, 2011) |
| "Creatine is an inexpensive and safe dietary supplement that has both peripheral and central effects." | 2.47 | Use of creatine in the elderly and evidence for effects on cognitive function in young and old. ( Rawson, ES; Venezia, AC, 2011) |
| "Creatine plays a role in cellular energy metabolism and potentially has a role in protein metabolism." | 2.41 | Potential benefits of creatine monohydrate supplementation in the elderly. ( Tarnopolsky, MA, 2000) |
| "Markers of nocturnal hypoxemia and SDB are associated with cerebral oxidative stress in older people at-risk for dementia, suggesting a potential mechanism by which SDB may contribute to brain degeneration, cognitive decline, and dementia." | 1.43 | Association of Anterior Cingulate Glutathione with Sleep Apnea in Older Adults At-Risk for Dementia. ( Cross, N; Duffy, SL; Grunstein, R; Hermens, DF; Hickie, IB; Lagopoulos, J; Lewis, SJ; Mowszowski, L; Naismith, SL; Terpening, Z, 2016) |
| "Bioenergetic failure is a feature of Alzheimer's disease (AD)." | 1.40 | Reduced levels of mitochondrial complex I subunit NDUFB8 and linked complex I + III oxidoreductase activity in the TgCRND8 mouse model of Alzheimer's disease. ( Bazinet, RP; Francis, BM; Gupta, S; Maj, M; Mount, HT; Robinson, B; Song, BJ; Yang, J, 2014) |
| "CL/F was comparable in ESRD and severe renal impairment." | 1.40 | Pharmacokinetics of topiramate in patients with renal impairment, end-stage renal disease undergoing hemodialysis, or hepatic impairment. ( Curtin, CR; Ford, L; Heald, DL; Manitpisitkul, P; Shalayda, K; Wang, SS, 2014) |
| "Patients with late-life major depressive disorder had a significantly lower NAA/creatine ratio in the left frontal white matter, and higher Cho/creatine and myo-inositol/creatine ratios in the left basal ganglia when compared with the control subjects." | 1.35 | Proton magnetic resonance spectroscopy of late-life major depressive disorder. ( Chen, CS; Chiang, IC; Hsieh, TJ; Kuo, YT; Li, CW; Lin, HF; Lin, WC; Liu, GC; Lu, CY, 2009) |
| "Twenty-four patients with spastic diplegia and twenty-six healthy children were examined." | 1.35 | An age and gender dependency of metabolite concentrations in basal ganglia in children with spastic diplegia: proton magnetic resonance spectroscopy study. ( Kubas, B; Kulak, W; Otapowicz, D; Smigielska-Kuzia, J; Sobaniec, W; Zawada, B, 2009) |
| "Tramadol clearance was described using a two-compartment, zero-order input, first-order elimination linear model." | 1.35 | Covariates of tramadol disposition in the first months of life. ( Allegaert, K; Anderson, BJ; de Hoon, JN; Debeer, A; Naulaers, G; Tibboel, D; van den Anker, JN; van Schaik, RH, 2008) |
| "A rat model of intrauterine growth retardation was employed." | 1.31 | Prenatal programming of adult hypertension in the rat. ( Aviles, DH; Manning, J; Vehaskari, VM, 2001) |
| "5-1 mM was toxic to embryonic hippocampal neurons." | 1.31 | Protective effect of the energy precursor creatine against toxicity of glutamate and beta-amyloid in rat hippocampal neurons. ( Brewer, GJ; Wallimann, TW, 2000) |
| "Taurine is a sulfur amino acid that is present in high concentration in mammalian tissues and previously has been reported to decline in a number of tissues with advancing age." | 1.30 | Effects of dietary taurine supplementation or deprivation in aged male Fischer 344 rats. ( Dawson, R; Eppler, B; Liu, S; Patterson, T, 1999) |
| "Choline was high at birth and declined thereafter." | 1.28 | In vivo 1H and 31P NMR spectroscopy of the developing rat brain. ( Hida, K; Kwee, IL; Nakada, T, 1992) |
| "Creatine was correspondingly increased, but total creatine was unchanged, as were the ATP and the ATP/ADP ratio." | 1.26 | Effect of aging on energy-rich phosphagens in human skeletal muscles. ( Bergström, J; Fürst, P; Hellström, K; Möller, P, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 39 (18.31) | 18.7374 |
| 1990's | 39 (18.31) | 18.2507 |
| 2000's | 60 (28.17) | 29.6817 |
| 2010's | 59 (27.70) | 24.3611 |
| 2020's | 16 (7.51) | 2.80 |
| Authors | Studies |
|---|---|
| Hone-Blanchet, A | 1 |
| Bohsali, A | 1 |
| Krishnamurthy, LC | 1 |
| Shahid, S | 1 |
| Lin, Q | 1 |
| Zhao, L | 1 |
| Loring, D | 1 |
| Goldstein, F | 1 |
| John, SE | 1 |
| Fleischer, CC | 1 |
| Levey, A | 1 |
| Lah, J | 1 |
| Qiu, D | 1 |
| Crosson, B | 1 |
| Forbes, SC | 5 |
| Ostojic, SM | 3 |
| Souza-Junior, TP | 1 |
| Candow, DG | 10 |
| Tran, NT | 1 |
| Kelly, SB | 1 |
| Snow, RJ | 1 |
| Walker, DW | 1 |
| Ellery, SJ | 1 |
| Galinsky, R | 1 |
| Rodríguez-Nieto, G | 1 |
| Levin, O | 2 |
| Hermans, L | 1 |
| Weerasekera, A | 1 |
| Sava, AC | 1 |
| Haghebaert, A | 1 |
| Huybrechts, A | 1 |
| Cuypers, K | 1 |
| Mantini, D | 1 |
| Himmelreich, U | 2 |
| Swinnen, SP | 1 |
| Vints, WAJ | 1 |
| Ziv, G | 1 |
| Katkutė, G | 1 |
| Kušleikienė, S | 1 |
| Valatkevičienė, K | 1 |
| Sheoran, S | 1 |
| Drozdova-Statkevičienė, M | 1 |
| Gleiznienė, R | 1 |
| Pääsuke, M | 1 |
| Dudonienė, V | 1 |
| Česnaitienė, VJ | 1 |
| Masiulis, N | 1 |
| Mahmoudi, N | 1 |
| Dadak, M | 2 |
| Bronzlik, P | 2 |
| Maudsley, AA | 2 |
| Sheriff, S | 1 |
| Lanfermann, H | 2 |
| Ding, XQ | 2 |
| Dolan, E | 1 |
| Artioli, GG | 1 |
| Pereira, RMR | 1 |
| Gualano, B | 4 |
| Demnitz, N | 1 |
| Topiwala, A | 1 |
| Zsoldos, E | 1 |
| Stagg, CJ | 1 |
| Emir, UE | 2 |
| Johansen-Berg, H | 1 |
| Ebmeier, KP | 1 |
| Sexton, CE | 1 |
| Lyros, E | 1 |
| Ragoschke-Schumm, A | 1 |
| Kostopoulos, P | 1 |
| Sehr, A | 1 |
| Backens, M | 1 |
| Kalampokini, S | 1 |
| Decker, Y | 1 |
| Lesmeister, M | 1 |
| Liu, Y | 1 |
| Reith, W | 1 |
| Fassbender, K | 1 |
| Vyssokikh, MY | 1 |
| Holtze, S | 1 |
| Averina, OA | 1 |
| Lyamzaev, KG | 1 |
| Panteleeva, AA | 1 |
| Marey, MV | 1 |
| Zinovkin, RA | 1 |
| Severin, FF | 1 |
| Skulachev, MV | 1 |
| Fasel, N | 1 |
| Hildebrandt, TB | 1 |
| Skulachev, VP | 1 |
| Marshall, RN | 1 |
| Smeuninx, B | 1 |
| Morgan, PT | 1 |
| Breen, L | 1 |
| McKendry, J | 1 |
| Currier, BS | 1 |
| Lim, C | 1 |
| Mcleod, JC | 1 |
| Thomas, ACQ | 1 |
| Phillips, SM | 2 |
| Deelchand, DK | 3 |
| McCarten, JR | 2 |
| Hemmy, LS | 2 |
| Auerbach, EJ | 1 |
| Eberly, LE | 1 |
| Marjańska, M | 3 |
| Kreider, RB | 1 |
| Stout, JR | 1 |
| Roschel, H | 2 |
| Rawson, ES | 4 |
| Kirk, B | 1 |
| Duque, G | 1 |
| Roberts, MD | 1 |
| Chilibeck, PD | 4 |
| Hodges, J | 1 |
| Grant, A | 1 |
| Terpstra, M | 2 |
| Zhao, MM | 1 |
| Gong, DQ | 1 |
| Gao, T | 1 |
| Zhang, L | 1 |
| Li, JL | 1 |
| Lv, PA | 1 |
| Yu, LL | 1 |
| Gao, F | 1 |
| Zhou, GH | 1 |
| Münzer, T | 1 |
| Schmitz, B | 1 |
| Wang, X | 2 |
| Barker, PB | 3 |
| Pilatus, U | 1 |
| Kahl, KG | 1 |
| Yang, JJ | 1 |
| Jeong, DH | 1 |
| Lim, YK | 1 |
| Kougias, DG | 1 |
| Das, T | 1 |
| Perez, AB | 1 |
| Pereira, SL | 1 |
| Jarak, I | 1 |
| Almeida, S | 1 |
| Carvalho, RA | 1 |
| Sousa, M | 1 |
| Barros, A | 1 |
| Alves, MG | 1 |
| Oliveira, PF | 1 |
| Cleeland, C | 1 |
| Pipingas, A | 1 |
| Scholey, A | 1 |
| White, D | 1 |
| Mellen, EJ | 1 |
| Harper, DG | 1 |
| Ravichandran, C | 1 |
| Jensen, E | 1 |
| Silveri, M | 1 |
| Forester, BP | 1 |
| Sporn, L | 1 |
| MacMillan, EL | 1 |
| Ge, R | 1 |
| Greenway, K | 1 |
| Vila-Rodriguez, F | 1 |
| Laule, C | 1 |
| Fried, PJ | 1 |
| Pascual-Leone, A | 1 |
| Bolo, NR | 1 |
| Zhang, X | 2 |
| Wu, J | 1 |
| Liu, H | 1 |
| Chiu, PW | 1 |
| Mak, HK | 1 |
| Yau, KK | 1 |
| Chan, Q | 1 |
| Chang, RC | 1 |
| Chu, LW | 1 |
| Gomar, JJ | 1 |
| Gordon, ML | 1 |
| Dickinson, D | 1 |
| Kingsley, PB | 1 |
| Uluğ, AM | 2 |
| Keehlisen, L | 1 |
| Huet, S | 1 |
| Buthorn, JJ | 1 |
| Koppel, J | 1 |
| Christen, E | 1 |
| Conejero-Goldberg, C | 1 |
| Davies, P | 1 |
| Goldberg, TE | 1 |
| Souza, WM | 1 |
| Heck, TG | 1 |
| Wronski, EC | 1 |
| Ulbrich, AZ | 1 |
| Boff, E | 1 |
| Mori, T | 1 |
| Mori, K | 1 |
| Ito, H | 1 |
| Goji, A | 1 |
| Miyazaki, M | 1 |
| Harada, M | 2 |
| Kurosawa, K | 1 |
| Kagami, S | 1 |
| Francis, BM | 1 |
| Yang, J | 1 |
| Song, BJ | 1 |
| Gupta, S | 1 |
| Maj, M | 1 |
| Bazinet, RP | 1 |
| Robinson, B | 1 |
| Mount, HT | 1 |
| Moon, A | 1 |
| Heywood, L | 1 |
| Rutherford, S | 1 |
| Cobbold, C | 1 |
| Ono, K | 1 |
| Kitagawa, M | 1 |
| Ito, D | 1 |
| Tanaka, N | 1 |
| Watari, T | 1 |
| Manitpisitkul, P | 1 |
| Curtin, CR | 1 |
| Shalayda, K | 1 |
| Wang, SS | 1 |
| Ford, L | 1 |
| Heald, DL | 1 |
| Abdel-Aziz, K | 1 |
| Solanky, BS | 1 |
| Yiannakas, MC | 1 |
| Altmann, DR | 1 |
| Wheeler-Kingshott, CA | 1 |
| Thompson, AJ | 2 |
| Ciccarelli, O | 1 |
| Mazgaj, R | 1 |
| Tal, A | 1 |
| Goetz, R | 1 |
| Lazar, M | 1 |
| Rothman, K | 1 |
| Messinger, JW | 1 |
| Malaspina, D | 1 |
| Gonen, O | 3 |
| Vogt, E | 1 |
| Johannsmeyer, S | 2 |
| Farthing, JP | 2 |
| Denison, HJ | 1 |
| Cooper, C | 1 |
| Sayer, AA | 1 |
| Robinson, SM | 1 |
| Vaes, B | 1 |
| Beke, E | 1 |
| Truyers, C | 1 |
| Elli, S | 1 |
| Buntinx, F | 1 |
| Verbakel, JY | 1 |
| Goderis, G | 1 |
| Van Pottelbergh, G | 1 |
| Tsili, AC | 1 |
| Astrakas, LG | 1 |
| Ntorkou, A | 1 |
| Giannakis, D | 1 |
| Stavrou, S | 1 |
| Maliakas, V | 1 |
| Sofikitis, N | 1 |
| Argyropoulou, MI | 1 |
| Baker, TP | 1 |
| Duffy, SL | 1 |
| Lagopoulos, J | 1 |
| Terpening, Z | 1 |
| Lewis, SJ | 1 |
| Grunstein, R | 1 |
| Mowszowski, L | 1 |
| Cross, N | 1 |
| Hermens, DF | 1 |
| Hickie, IB | 1 |
| Naismith, SL | 1 |
| Brandt, AS | 1 |
| Unschuld, PG | 1 |
| Pradhan, S | 1 |
| Lim, IA | 1 |
| Churchill, G | 1 |
| Harris, AD | 1 |
| Hua, J | 1 |
| Ross, CA | 1 |
| van Zijl, PC | 1 |
| Edden, RA | 1 |
| Margolis, RL | 1 |
| Collins, J | 1 |
| Longhurst, G | 1 |
| Löbel, U | 1 |
| Hwang, S | 1 |
| Edwards, A | 1 |
| Li, Y | 1 |
| Li, X | 1 |
| Broniscer, A | 1 |
| Patay, Z | 1 |
| Scheer, M | 1 |
| Bischoff, AM | 1 |
| Kruzliak, P | 1 |
| Opatrilova, R | 1 |
| Bovell, D | 1 |
| Büsselberg, D | 1 |
| Baroncelli, L | 1 |
| Molinaro, A | 1 |
| Cacciante, F | 1 |
| Alessandrì, MG | 1 |
| Napoli, D | 1 |
| Putignano, E | 1 |
| Tola, J | 1 |
| Leuzzi, V | 1 |
| Cioni, G | 1 |
| Pizzorusso, T | 1 |
| Brahms, CM | 1 |
| Michel, D | 1 |
| Zello, GA | 1 |
| Tosato, M | 1 |
| Marzetti, E | 1 |
| Cesari, M | 1 |
| Savera, G | 1 |
| Miller, RR | 1 |
| Bernabei, R | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Creatine Supplementation and Resistance Training in Patients With Breast Cancer (CaRTiC Study)[NCT05878106] | 120 participants (Anticipated) | Interventional | 2024-01-08 | Not yet recruiting | |||
| The Effect of Creatine Monohydrate on Persistent Post-concussive Symptoms - a Pilot Study Protocol[NCT05562232] | 45 participants (Anticipated) | Interventional | 2022-10-01 | Not yet recruiting | |||
| Effects of Creatine and Caffeine Co-Supplementation on Muscle Mass and Muscle Performance in Trained Young Adults[NCT04290819] | 36 participants (Anticipated) | Interventional | 2019-02-15 | Recruiting | |||
| Project Arthritis Recovering Quality of Life Through Education 70+[NCT04058002] | 34 participants (Anticipated) | Interventional | 2019-08-15 | Not yet recruiting | |||
| Different Protein and Derivatives Supplementation Strategies Combined With Resistance Training in Pre-frail and Frail Elderly[NCT01890382] | 200 participants (Actual) | Interventional | 2015-10-01 | Completed | |||
| Sarcopenia and Risk of Fall in Elder Post-menopausal Osteoporotic Women: a Pilot Study[NCT03382366] | 40 participants (Anticipated) | Interventional | 2017-03-29 | Recruiting | |||
| Prematurity as Predictor of Children's Cardiovascular-renal Health (PREMATCH)[NCT02147457] | 180 participants (Actual) | Observational | 2014-10-31 | Completed | |||
| The Effects of PeakATP (Adenosine 5' - Triphosphate Disodium) Supplementation vs. Placebo on Measures of Mood, Reaction Time and Cognitive Performance[NCT05100589] | 35 participants (Actual) | Interventional | 2021-10-06 | Completed | |||
| Creatine Monohydrate and Conjugated Linoleic Acid Improve Strength and Body Composition Following Resistance Exercise in Older Adults[NCT00473902] | 39 participants (Actual) | Interventional | 2003-08-31 | Completed | |||
| Exercise and Nutritional Supplementation for Aging and Sedentary Lifestyles[NCT03536871] | 45 participants (Actual) | Interventional | 2018-05-01 | Completed | |||
| Effect of Conjugated Linoleic Acid Associated With Aerobic Exercise on Body Fat and Lipid Profile in Obese Women: A Randomized, Double-blinded and Placebo-controlled Trial[NCT02529046] | 28 participants (Actual) | Interventional | 2007-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
31 reviews available for creatine and Aging
| Article | Year |
|---|---|
Assessing Creatine Supplementation for Neuroprotection against Perinatal Hypoxic-Ischaemic Encephalopathy: A Systematic Review of Perinatal and Adult Pre-Clinical Studies.
Topics: Aging; Animals; Creatine; Dietary Supplements; Female; Hypoxia-Ischemia, Brain; Male; Neuroprotectio | 2021 |
Muscular Atrophy and Sarcopenia in the Elderly: Is There a Role for Creatine Supplementation?
Topics: Aged; Aging; Animals; Creatine; Dietary Supplements; Exercise; Humans; Muscular Atrophy | 2019 |
Nutritional Strategies to Offset Disuse-Induced Skeletal Muscle Atrophy and Anabolic Resistance in Older Adults: From Whole-Foods to Isolated Ingredients.
Topics: Aged; Aging; Creatine; Diet, High-Protein; Dietary Proteins; Dietary Supplements; Exercise; Fatty Ac | 2020 |
Nutritional Supplements to Support Resistance Exercise in Countering the Sarcopenia of Aging.
Topics: Aged; Aging; Creatine; Diet; Dietary Proteins; Dietary Supplements; Exercise; Fatty Acids, Omega-3; | 2020 |
Creatine in Health and Disease.
Topics: Aging; Biological Availability; Chronic Disease; Creatine; Dietary Supplements; Humans; Wounds and I | 2021 |
Creatine in Health and Disease.
Topics: Aging; Biological Availability; Chronic Disease; Creatine; Dietary Supplements; Humans; Wounds and I | 2021 |
Creatine in Health and Disease.
Topics: Aging; Biological Availability; Chronic Disease; Creatine; Dietary Supplements; Humans; Wounds and I | 2021 |
Creatine in Health and Disease.
Topics: Aging; Biological Availability; Chronic Disease; Creatine; Dietary Supplements; Humans; Wounds and I | 2021 |
Creatine Supplementation and Brain Health.
Topics: Aging; Alzheimer Disease; Blood-Brain Barrier; Brain; Brain Concussion; Brain Injuries; Cognition; C | 2021 |
Current Evidence and Possible Future Applications of Creatine Supplementation for Older Adults.
Topics: Aged; Aged, 80 and over; Aging; Bone Density; Creatine; Dietary Supplements; Exercise; Female; Human | 2021 |
Meta-Analysis Examining the Importance of Creatine Ingestion Strategies on Lean Tissue Mass and Strength in Older Adults.
Topics: Aged; Aging; Creatine; Dietary Supplements; Eating; Food, Fortified; Humans; Muscle Strength; Muscle | 2021 |
[Doping with illegal and legal substances in old age].
Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Creatine; Doping in Sports; Female; Humans; Illi | 2018 |
A role for nutritional intervention in addressing the aging neuromuscular junction.
Topics: Aging; Creatine; Diet; Dietary Proteins; Dietary Supplements; Fatty Acids, Omega-3; Humans; Muscle, | 2018 |
Neurochemical changes in the aging brain: A systematic review.
Topics: Aging; Alzheimer Disease; Animals; Brain; Choline; Cognition; Creatine; Humans | 2019 |
Creatine supplementation and aging musculoskeletal health.
Topics: Aging; Creatine; Humans; Osteoporosis; Resistance Training; Sarcopenia | 2014 |
Creatine supplementation: can it improve quality of life in the elderly without associated resistance training?
Topics: Activities of Daily Living; Age Factors; Aged; Aging; Anabolic Agents; Creatine; Dietary Supplements | 2013 |
Prevention and optimal management of sarcopenia: a review of combined exercise and nutrition interventions to improve muscle outcomes in older people.
Topics: Aged; Aging; Creatine; Diet; Dietary Proteins; Dietary Supplements; Exercise; Exercise Therapy; Huma | 2015 |
Nutritional supplements in support of resistance exercise to counter age-related sarcopenia.
Topics: Aged; Aging; Creatine; Diet; Dietary Proteins; Dietary Supplements; Fatty Acids, Omega-3; Female; Hu | 2015 |
Creatine supplementation in the aging population: effects on skeletal muscle, bone and brain.
Topics: Aged, 80 and over; Aging; Bone and Bones; Brain; Creatine; Dietary Supplements; Female; Humans; Male | 2016 |
Creatine supplementation in the aging population: effects on skeletal muscle, bone and brain.
Topics: Aged, 80 and over; Aging; Bone and Bones; Brain; Creatine; Dietary Supplements; Female; Humans; Male | 2016 |
Creatine supplementation in the aging population: effects on skeletal muscle, bone and brain.
Topics: Aged, 80 and over; Aging; Bone and Bones; Brain; Creatine; Dietary Supplements; Female; Humans; Male | 2016 |
Creatine supplementation in the aging population: effects on skeletal muscle, bone and brain.
Topics: Aged, 80 and over; Aging; Bone and Bones; Brain; Creatine; Dietary Supplements; Female; Humans; Male | 2016 |
Measurement of muscle mass in sarcopenia: from imaging to biochemical markers.
Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Aging; Anthropometry; Biomarkers; Body Composition; | 2017 |
Validated treatments and therapeutics prospectives regarding pharmacological products for sarcopenia.
Topics: Aged; Aging; Anabolic Agents; Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Cr | 2009 |
Potential of creatine supplementation for improving aging bone health.
Topics: Aged; Aged, 80 and over; Aging; Bone Density; Creatine; Dietary Supplements; Female; Humans; Male; M | 2010 |
Sarcopenia: current theories and the potential beneficial effect of creatine application strategies.
Topics: Aged; Aging; Creatine; Dietary Supplements; Humans; Middle Aged; Muscle Proteins; Muscle Strength; M | 2011 |
Creatine in mouse models of neurodegeneration and aging.
Topics: Aging; Animals; Creatine; Disease Models, Animal; Humans; Mice; Neurodegenerative Diseases; Rejuvena | 2011 |
Use of creatine in the elderly and evidence for effects on cognitive function in young and old.
Topics: Aging; Cognition; Creatine; Dietary Supplements; Humans | 2011 |
Metabolic agents that enhance ATP can improve cognitive functioning: a review of the evidence for glucose, oxygen, pyruvate, creatine, and L-carnitine.
Topics: Adenosine Triphosphate; Aging; Brain; Carnitine; Cognition; Cognition Disorders; Creatine; Energy Me | 2011 |
HUMAN BIOLOGY AND RESEARCH IN BODY COMPOSITION.
Topics: Aging; Body Composition; Bone and Bones; Creatine; Creatinine; Humans; Minerals; Muscles; Tooth; Uri | 1963 |
[PHYSIOPATHOLOGICAL AND CLINICAL ASPECTS OF THERAPY IN THE AGED PATIENT].
Topics: Absorption; Aging; Blood; Cinnamates; Creatine; Creatinine; Drug Therapy; Geriatrics; Humans; Pharma | 1964 |
N-acetylaspartate as a marker of neuronal injury in neurodegenerative disease.
Topics: Aging; Alcoholism; Amyotrophic Lateral Sclerosis; Aspartic Acid; Biomarkers; Brain; Brain Injuries; | 2006 |
Stimulation of skin's energy metabolism provides multiple benefits for mature human skin.
Topics: Administration, Topical; Adult; Aging; Coenzymes; Creatine; Energy Metabolism; Humans; Middle Aged; | 2005 |
The potential benefits of creatine and conjugated linoleic acid as adjuncts to resistance training in older adults.
Topics: Aged; Aging; Creatine; Exercise; Humans; Linoleic Acids, Conjugated; Muscular Atrophy; Physical Fitn | 2008 |
Potential benefits of creatine monohydrate supplementation in the elderly.
Topics: Aged; Aging; Creatine; Dietary Supplements; Exercise; Humans; Muscle, Skeletal; Proteins; Sports | 2000 |
Renal biochemistry in rheumatic disease.
Topics: Aging; Anti-Inflammatory Agents, Non-Steroidal; Biomechanical Phenomena; Blood Chemical Analysis; Cr | 1988 |
Transitional nephrology.
Topics: Adult; Aging; Animals; Blood Urea Nitrogen; Child; Child, Preschool; Creatine; Embryonic and Fetal D | 1985 |
17 trials available for creatine and Aging
| Article | Year |
|---|---|
Strategic creatine supplementation and resistance training in healthy older adults.
Topics: Absorptiometry, Photon; Aged; Aging; Body Composition; Creatine; Dietary Supplements; Double-Blind M | 2015 |
Effect of Preexercise Creatine Ingestion on Muscle Performance in Healthy Aging Males.
Topics: Aging; Creatine; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Exercise; Humans; Mal | 2016 |
Resistance Training and Co-supplementation with Creatine and Protein in Older Subjects with Frailty.
Topics: Absorptiometry, Photon; Aged; Aging; Body Composition; Creatine; Dietary Supplements; Double-Blind M | 2016 |
Effect of creatine supplementation and drop-set resistance training in untrained aging adults.
Topics: Aging; Body Composition; Canada; Creatine; Diet; Dietary Supplements; Double-Blind Method; Female; H | 2016 |
The effects of supplementation with creatine and protein on muscle strength following a traditional resistance training program in middle-aged and older men.
Topics: Aged; Aging; Body Composition; Creatine; Dietary Proteins; Dietary Supplements; Double-Blind Method; | 2010 |
The aging hippocampus: cognitive, biochemical and structural findings.
Topics: Adult; Aged; Aged, 80 and over; Aging; Aspartic Acid; Choline; Cognition; Creatine; Female; Hippocam | 2003 |
Long-term outcome of adding mycophenolate mofetil to tacrolimus for nephrotoxicity following liver transplantation.
Topics: Adult; Aged; Aging; Creatine; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kidney Fu | 2005 |
Reduced renal response to low-dose dopamine infusion in the elderly.
Topics: Adult; Aged; Aging; Creatine; Diuresis; Dopamine; Dose-Response Relationship, Drug; Humans; Infusion | 1995 |
Proton spectroscopy of human brain: effects of age and sex.
Topics: Adult; Aged; Aging; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Female; Humans; Magnet | 1994 |
Effects of creatine monohydrate ingestion in sedentary and weight-trained older adults.
Topics: Aged; Aged, 80 and over; Aging; Anthropometry; Creatine; Diet; Exercise; Female; Humans; Male; Muscl | 1998 |
Acute creatine supplementation in older men.
Topics: Aged; Aging; Body Composition; Creatine; Dietary Supplements; Exercise; Humans; Male; Middle Aged; M | 2000 |
Aging alters regional multichemical profile of the human brain: an in vivo 1H-MRS study of young versus middle-aged subjects.
Topics: Adult; Age Factors; Aging; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Female; gamma-A | 2001 |
Aging alters the multichemical networking profile of the human brain: an in vivo (1)H-MRS study of young versus middle-aged subjects.
Topics: Adult; Aging; Analysis of Variance; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Female | 2001 |
Neuromuscular properties and fatigue in older men following acute creatine supplementation.
Topics: Aged; Aged, 80 and over; Aging; Creatine; Elbow Joint; Electromyography; Humans; Male; Muscle Contra | 2001 |
Effects of oral creatine supplementation on maximal pedalling performance in older adults.
Topics: Administration, Oral; Adult; Aged; Aging; Creatine; Exercise; Exercise Test; Heart Rate; Humans; Mal | 2001 |
Effects of naproxen on renal function in older patients with mild to moderate renal dysfunction.
Topics: Aged; Aging; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Creatine; Dinoprostone; Dose-R | 1992 |
Importance of the renin-angiotensin system in sodium regulation in essential hypertension.
Topics: Adult; Aging; Arginine Vasopressin; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Creatine | 1991 |
165 other studies available for creatine and Aging
| Article | Year |
|---|---|
Relationships between frontal metabolites and Alzheimer's disease biomarkers in cognitively normal older adults.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Aspartic Acid; Biomarkers; Cognition; Creatine; Fem | 2022 |
A High Dose of Creatine Combined with Resistance Training Appears to Be Required to Augment Indices of Bone Health in Older Adults.
Topics: Aged; Aging; Bone and Bones; Bone Density; Creatine; Dietary Supplements; Double-Blind Method; Human | 2022 |
Organization of neurochemical interactions in young and older brains as revealed with a network approach: Evidence from proton magnetic resonance spectroscopy (
Topics: Aged; Aging; Aspartic Acid; Brain; Choline; Creatine; Humans; Inositol; Motor Cortex; Prefrontal Cor | 2023 |
Neurometabolic correlates of posturography in normal aging and older adults with mild cognitive impairment: Evidence from a
Topics: Aged; Aging; Aspartic Acid; Choline; Cognitive Dysfunction; Creatine; Glutamine; Humans; Inositol; P | 2023 |
Microstructural and Metabolic Changes in Normal Aging Human Brain Studied with Combined Whole-Brain MR Spectroscopic Imaging and Quantitative MR Imaging.
Topics: Aging; Aspartic Acid; Brain; Choline; Creatine; Humans; Inositol; Magnetic Resonance Imaging; Magnet | 2023 |
Alcohol consumption is associated with reduced creatine levels in the hippocampus of older adults.
Topics: Aged; Aging; Alcohol Drinking; Cohort Studies; Creatine; Female; Hippocampus; Humans; Magnetic Reson | 2020 |
Normal brain aging and Alzheimer's disease are associated with lower cerebral pH: an in vivo histidine
Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Brain; Cognitive Dysfunction; Creatine; De | 2020 |
Mild depolarization of the inner mitochondrial membrane is a crucial component of an anti-aging program.
Topics: Adenosine Diphosphate; Aging; Animals; Chiroptera; Creatine; Electron Transport; Embryo, Mammalian; | 2020 |
Changes in the intracellular microenvironment in the aging human brain.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Aspartic Acid; Brain; Brain Chemistry; Cellular M | 2020 |
Region-specific aging of the human brain as evidenced by neurochemical profiles measured noninvasively in the posterior cingulate cortex and the occipital lobe using
Topics: Aged; Aged, 80 and over; Aging; Ascorbic Acid; Aspartic Acid; Brain Chemistry; Creatine; Dipeptides; | 2017 |
In ovo feeding of creatine pyruvate modulates growth performance, energy reserves and mRNA expression levels of gluconeogenesis and glycogenesis enzymes in liver of embryos and neonatal broilers.
Topics: Aging; Animals; Chick Embryo; Chickens; Creatine; Gene Expression Regulation, Developmental; Gene Ex | 2018 |
Effects of Aging on the Human Brain: A Proton and Phosphorus MR Spectroscopy Study at 3T.
Topics: Adult; Aged; Aging; Biomarkers; Brain; Choline; Creatine; Female; Gray Matter; Humans; Magnetic Reso | 2018 |
Blood Chemistry Reference Values for Free-Ranging Asiatic Black Bears ( Ursus thibetanus) by Season, Age, and Sex.
Topics: Aging; Ammonia; Animals; Bilirubin; Blood Glucose; Blood Urea Nitrogen; Cholesterol; Creatine; Femal | 2018 |
Senescence and declining reproductive potential: Insight into molecular mechanisms through testicular metabolomics.
Topics: Aging; Animals; Betaine; Creatine; Fertility; Glutathione; Magnetic Resonance Spectroscopy; Male; Me | 2018 |
Lamotrigine Therapy and Biomarkers of Cerebral Energy Metabolism in Older Age Bipolar Depression.
Topics: Aged; Aging; Antipsychotic Agents; Aspartic Acid; Biomarkers; Bipolar Disorder; Cerebral Cortex; Cre | 2019 |
Longer Repetition Time Proton MR Spectroscopy Shows Increasing Hippocampal and Parahippocampal Metabolite Concentrations with Aging.
Topics: Adolescent; Adult; Aging; Aspartic Acid; Choline; Creatine; Female; Glutamic Acid; Glutamine; Hippoc | 2019 |
Diabetes and the link between neuroplasticity and glutamate in the aging human motor cortex.
Topics: Aged; Aged, 80 and over; Aging; Aspartic Acid; Creatine; Diabetes Mellitus, Type 2; Female; Glucose; | 2019 |
Age- and gender-related metabonomic alterations in striatum and cerebellar cortex in rats.
Topics: Aging; Animals; Cerebellar Cortex; Corpus Striatum; Creatine; Female; Glutamic Acid; Inositol; Lacti | 2013 |
Metabolic changes in the anterior and posterior cingulate cortices of the normal aging brain: proton magnetic resonance spectroscopy study at 3 T.
Topics: Adult; Aged; Aged, 80 and over; Aging; Aspartic Acid; Brain Chemistry; China; Choline; Creatine; Fem | 2014 |
APOE genotype modulates proton magnetic resonance spectroscopy metabolites in the aging brain.
Topics: Aged; Aged, 80 and over; Aging; Apolipoprotein E3; Apolipoprotein E4; Apolipoproteins E; Brain; Chol | 2014 |
Effects of creatine supplementation on biomarkers of hepatic and renal function in young trained rats.
Topics: Aging; Anabolic Agents; Animals; Biomarkers; Creatine; Kidney; Kidney Function Tests; Liver; Liver F | 2013 |
Age-related changes in a patient with Pelizaeus-Merzbacher disease determined by repeated 1H-magnetic resonance spectroscopy.
Topics: Aging; Aspartic Acid; Case-Control Studies; Child, Preschool; Creatine; gamma-Aminobutyric Acid; Glu | 2014 |
Faster metabolite (1)H transverse relaxation in the elder human brain.
Topics: Adolescent; Aged; Aged, 80 and over; Aging; Aspartic Acid; Cellular Microenvironment; Choline; Creat | 2013 |
Reduced levels of mitochondrial complex I subunit NDUFB8 and linked complex I + III oxidoreductase activity in the TgCRND8 mouse model of Alzheimer's disease.
Topics: Adenosine Triphosphate; Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cardiolip | 2014 |
Regional variations and age-related changes detected with magnetic resonance spectroscopy in the brain of healthy dogs.
Topics: Aging; Animals; Aspartic Acid; Brain; Choline; Creatine; Dogs; Female; Lactic Acid; Magnetic Resonan | 2014 |
Pharmacokinetics of topiramate in patients with renal impairment, end-stage renal disease undergoing hemodialysis, or hepatic impairment.
Topics: Adult; Aged; Aging; Anticonvulsants; Creatine; Female; Fructose; Humans; Kidney Failure, Chronic; Li | 2014 |
Age related changes in metabolite concentrations in the normal spinal cord.
Topics: Adult; Age Factors; Aged; Aging; Aspartic Acid; Choline; Creatine; Female; Glutamic Acid; Glutamine; | 2014 |
Hypo-metabolism of the rostral anterior cingulate cortex associated with working memory impairment in 18 cases of schizophrenia.
Topics: Adult; Aging; Aspartic Acid; Creatine; Female; Gliosis; Gyrus Cinguli; Humans; Inositol; Intelligenc | 2016 |
The correlation between blood pressure and kidney function decline in older people: a registry-based cohort study.
Topics: Aged; Aged, 80 and over; Aging; Belgium; Blood Pressure; Comorbidity; Creatine; Glomerular Filtratio | 2015 |
MR Spectra of Normal Adult Testes and Variations with Age: Preliminary Observations.
Topics: Adult; Age Factors; Aged; Aging; Choline; Creatine; Humans; Inositol; Magnetic Resonance Spectroscop | 2016 |
Association of Anterior Cingulate Glutathione with Sleep Apnea in Older Adults At-Risk for Dementia.
Topics: Aged; Aging; Biomarkers; Cognition Disorders; Cognitive Dysfunction; Creatine; Dementia; Depression; | 2016 |
Age-related changes in anterior cingulate cortex glutamate in schizophrenia: A (1)H MRS Study at 7 Tesla.
Topics: Adult; Aging; Antipsychotic Agents; Aspartic Acid; Choline; Creatine; Dipeptides; Female; gamma-Amin | 2016 |
Discrepant longitudinal volumetric and metabolic evolution of diffuse intrinsic Pontine gliomas during treatment: implications for current response assessment strategies.
Topics: Adolescent; Aging; Aspartic Acid; Biomarkers, Tumor; Brain Stem; Brain Stem Neoplasms; Child; Child, | 2016 |
Creatine and creatine pyruvate reduce hypoxia-induced effects on phrenic nerve activity in the juvenile mouse respiratory system.
Topics: Aging; Animals; Creatine; Hypoxia; Mice; Motor Activity; Phrenic Nerve; Pyruvic Acid; Respiratory Sy | 2016 |
A mouse model for creatine transporter deficiency reveals early onset cognitive impairment and neuropathology associated with brain aging.
Topics: Aging; Animals; Brain; Brain Diseases, Metabolic, Inborn; Cognitive Dysfunction; Creatine; Disease M | 2016 |
Hypothalamic damage in multiple sclerosis correlates with disease activity, disability, depression, and fatigue.
Topics: Adult; Aging; Aspartic Acid; Case-Control Studies; Choline; Creatine; Cross-Sectional Studies; Depre | 2017 |
Age dependence of regional proton metabolites T2 relaxation times in the human brain at 3 T.
Topics: Adult; Aged; Aging; Aspartic Acid; Brain; Choline; Creatine; Female; Humans; Magnetic Resonance Spec | 2008 |
An age and gender dependency of metabolite concentrations in basal ganglia in children with spastic diplegia: proton magnetic resonance spectroscopy study.
Topics: Adolescent; Aging; Aspartic Acid; Basal Ganglia; Case-Control Studies; Cerebral Palsy; Child; Child, | 2009 |
Brain flexibility and balance and gait performances mark morphological and metabolic abnormalities in the elderly.
Topics: Aged; Aged, 80 and over; Aging; Aspartic Acid; Brain; Choline; Community Health Planning; Creatine; | 2008 |
N-acetylaspartate/creatine and choline/creatine ratios in the thalami, insular cortex and white matter as markers of hypertension and cognitive impairment in the elderly.
Topics: Aged; Aged, 80 and over; Aging; Aspartic Acid; Biomarkers; Cerebral Cortex; Choline; Cognition Disor | 2008 |
Screening for X-linked creatine transporter (SLC6A8) deficiency via simultaneous determination of urinary creatine to creatinine ratio by tandem mass-spectrometry.
Topics: Adolescent; Age Distribution; Aging; Child; Child, Preschool; Creatine; Creatinine; Female; Genes, X | 2009 |
Brain metabolism in Rett syndrome: age, clinical, and genotype correlations.
Topics: Adolescent; Aging; Analysis of Variance; Aspartic Acid; Case-Control Studies; Child; Child, Preschoo | 2009 |
Proton magnetic resonance spectroscopy of late-life major depressive disorder.
Topics: Aged; Aging; Aspartic Acid; Basal Ganglia; Biomarkers; Brain; Choline; Cognition; Creatine; Depressi | 2009 |
Copper deficiency alters the neurochemical profile of developing rat brain.
Topics: Aging; Animals; Ascorbic Acid; Aspartic Acid; Brain; Brain Chemistry; Cerebellum; Citric Acid; Coppe | 2009 |
1H NMR metabolomics study of age profiling in children.
Topics: Age Factors; Aging; Biomarkers; Child; Child, Preschool; Creatine; Humans; Infant; Infant, Newborn; | 2009 |
Regional age-related effects in the monkey brain measured with 1H magnetic resonance spectroscopy.
Topics: Aging; Animals; Aspartic Acid; Brain; Brain Mapping; Choline; Creatine; Humans; Image Processing, Co | 2011 |
Circulating endothelial progenitor cells and age-related white matter changes.
Topics: Age Distribution; Aged; Aging; Angiotensin-Converting Enzyme Inhibitors; Brain; C-Reactive Protein; | 2009 |
Ontogeny regulates creatine metabolism in rat small and large intestine.
Topics: Aging; Amidinotransferases; Animals; Animals, Newborn; Animals, Suckling; Blotting, Northern; Blotti | 2009 |
Metabolite concentrations in supraventricular white matter from teenage to early old age: A short echo time 1H magnetic resonance spectroscopy (MRS) study.
Topics: Adolescent; Adult; Age Factors; Aged; Aging; Aspartic Acid; Biomarkers; Brain; Choline; Creatine; Fe | 2010 |
Glycine-creatine metabolism in its relationship to aging.
Topics: Age Factors; Aging; Creatine; Glycine; Humans | 1947 |
Reduction of hippocampal N-acetyl aspartate level in aged APP(Swe)/PS1(dE9) transgenic mice is associated with degeneration of CA3 pyramidal neurons.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Benzothiazoles; CA | 2010 |
Maturation of limbic regions in Asperger syndrome: a preliminary study using proton magnetic resonance spectroscopy and structural magnetic resonance imaging.
Topics: Adolescent; Adult; Age Factors; Aging; Amygdala; Aspartic Acid; Asperger Syndrome; Brain Mapping; Ch | 2010 |
Age-related differences in metabolites in the posterior cingulate cortex and hippocampus of normal ageing brain: a 1H-MRS study.
Topics: Adolescent; Adult; Age Factors; Aged; Aging; Analysis of Variance; Aspartic Acid; Choline; Creatine; | 2012 |
Postnatal trends in creatinemia and its covariates in extremely low birth weight (ELBW) neonates.
Topics: Adult; Aging; Anti-Inflammatory Agents, Non-Steroidal; Apgar Score; Birth Weight; Cohort Studies; Cr | 2011 |
Longitudinal inter- and intra-individual human brain metabolic quantification over 3 years with proton MR spectroscopy at 3 T.
Topics: Aging; Algorithms; Aspartic Acid; Brain; Choline; Creatine; Humans; Inositol; Longitudinal Studies; | 2012 |
Daydreaming about our metaphorical tool belt.
Topics: Aging; Aspartic Acid; Brain; Brain Ischemia; Choline; Creatine; Female; Humans; Male | 2012 |
The effect of age and cerebral ischemia on diffusion-weighted proton MR spectroscopy of the human brain.
Topics: Adult; Aging; Aspartic Acid; Brain; Brain Ischemia; Choline; Creatine; Female; Humans; Male; Reprodu | 2012 |
Longitudinal evaluation of intramyocellular lipids (IMCLs) in tibialis anterior muscle of ob/ob and ob/+ control mice using a cryogenic surface coil at 9.4 T.
Topics: Aging; Animals; Body Weight; Cold Temperature; Creatine; Feasibility Studies; Insulin; Lipid Metabol | 2011 |
Age-related changes in brain metabolites and cognitive function in APP/PS1 transgenic mice.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Biomarkers; Cholin | 2012 |
Procedure for quantitative (1)H magnetic resonance spectroscopy and tissue characterization of human brain tissue based on the use of quantitative magnetic resonance imaging.
Topics: Adolescent; Adult; Aged; Aging; Creatine; Female; Humans; Inositol; Magnetic Resonance Imaging; Magn | 2013 |
Renal cortical nitric oxide synthase activity during maturational growth in the rat.
Topics: Aging; Animals; Body Weight; Creatine; Cyclic GMP; Enzyme Inhibitors; Hemodynamics; Kidney Cortex; L | 2002 |
Brain changes with aging: MR spectroscopy at supraventricular plane shows differences between women and men.
Topics: Aged; Aged, 80 and over; Aging; Aspartic Acid; Brain; Choline; Creatine; Female; Humans; Linear Mode | 2003 |
Presence of (phospho)creatine in developing and adult skeletal muscle of mice without mitochondrial and cytosolic muscle creatine kinase isoforms.
Topics: Adenylate Kinase; Aging; Animals; Creatine; Creatine Kinase; Creatine Kinase, MM Form; Cytosol; Hind | 2003 |
Memory training alters hippocampal neurochemistry in healthy elderly.
Topics: Aged; Aged, 80 and over; Aging; Aspartic Acid; Brain Chemistry; Brain Mapping; Cerebral Cortex; Chol | 2003 |
Urinary excretion after the age of ninety; a study of neutral 17-ketosteroids, creatinine, and creatine.
Topics: 17-Ketosteroids; Aged; Aging; Body Fluids; Creatine; Creatinine; Humans; Hydrogen-Ion Concentration; | 1956 |
[Creatinuria in aged rats & effects of d, 1-alpha-tocopherol acetate].
Topics: Aging; alpha-Tocopherol; Animals; Body Fluids; Creatine; Rats; Vitamin E | 1958 |
[Experiments on influencing creatinuria of age by alpha-tocopherol acetate and selenium].
Topics: Aging; alpha-Tocopherol; Creatine; Creatinine; Humans; Selenium; Selenium Compounds; Urinalysis; Vit | 1959 |
AGE AND SEX DIFFERENCES IN BODY DENSITY AND CREATININE EXCRETION OF HIGH SCHOOL CHILDREN.
Topics: Adolescent; Aging; Body Composition; Child; Creatine; Creatinine; Humans; Sex; Sex Characteristics; | 1963 |
BODY COMPOSITION STUDIES OF "OLDER" WOMEN, THIRTY TO SEVENTY YEARS OF AGE.
Topics: Adipose Tissue; Aging; Anthropometry; Body Composition; Creatine; Creatinine; Female; Geriatrics; Hu | 1963 |
TRENDS IN SELECTED INDICES OF BODY COMPOSITION IN MEN BETWEEN THE AGES 30 AND 80 YEARS.
Topics: Aging; Anthropometry; Body Composition; Creatine; Creatinine; Geriatrics; Humans; Male; Metabolism; | 1963 |
PLASMA CREATININE IN DIFFERENT SEX AND AGE GROUPS OF A HEALTHY ISOLATED ISLAND POPULATION.
Topics: Aging; Biometry; Blood Chemical Analysis; Creatine; Creatinine; Finland; Islands; Kidney Function Te | 1964 |
SERUM CREATINE AND CREATININE IN AGEING ALBINO RATS.
Topics: Aging; Blood; Creatine; Creatinine; Rats; Research | 1964 |
SERUM AND MUSCLE CREATINE IN EXERCISED AGEING RATS.
Topics: Aging; Blood; Body Weight; Creatine; Creatinine; Exercise; Metabolism; Muscles; Physical Exertion; R | 1964 |
AMINO ACID REQUIREMENTS OF CHILDREN: QUANTITATIVE AMINO ACID REQUIREMENTS OF GIRLS BASED ON NITROGEN BALANCE METHOD.
Topics: 17-Ketosteroids; Aging; Amino Acids; Basal Metabolism; Body Height; Body Weight; Child; Creatine; Cr | 1965 |
[INFLUENCE ON A ANABOLIC STEROID ON BEHAVIOR OF URINARY CREATINE AND CREATININE AT VARIOUS AGES. EXPERIMENTAL RESEARCH].
Topics: Aging; Anabolic Agents; Animals; Body Fluids; Creatine; Creatinine; Guinea Pigs; Research; Steroids; | 1965 |
[The metabolism of creatinic bodies in senescent animals].
Topics: Aging; Biochemical Phenomena; Coenzymes; Creatine; Creatinine | 1960 |
Perinatal iron deficiency alters the neurochemical profile of the developing rat hippocampus.
Topics: Aging; Animals; Aspartic Acid; Body Weight; Brain; Brain Chemistry; Creatine; Ethanolamines; Female; | 2003 |
Quantitative MR analyses of the hippocampus: unspecific metabolic changes in aging.
Topics: Adult; Age Factors; Aged; Aging; Analysis of Variance; Aspartic Acid; Attention; Brain Chemistry; Ch | 2004 |
The age-related increase in N-methyl-2-pyridone-5-carboxamide (NAD catabolite) in human plasma.
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Aging; Animals; Blood Urea Nitrogen; C | 2004 |
Age-related glutamate and glutamine concentration changes in normal human brain: 1H MR spectroscopy study at 4 T.
Topics: Adult; Aged; Aging; Analysis of Variance; Aspartic Acid; Brain Chemistry; Creatine; Female; Glutamic | 2005 |
Developmental decrease in rat small intestinal creatine uptake.
Topics: Aging; Animals; Biological Transport, Active; Creatine; Ileum; Jejunum; Rats; Rats, Wistar | 2005 |
No effects of lifelong creatine supplementation on sarcopenia in senescence-accelerated mice (SAMP8).
Topics: Aging; Animals; Creatine; Dietary Supplements; Energy Metabolism; Male; Mice; Mice, Inbred Strains; | 2005 |
Age-related metabolic changes in the upper brainstem tegmentum by MR spectroscopy.
Topics: Adult; Aged; Aging; Analysis of Variance; Aspartic Acid; Brain Mapping; Choline; Creatine; Female; H | 2005 |
High resolution 1H NMR-based metabolomics indicates a neurotransmitter cycling deficit in cerebral tissue from a mouse model of Batten disease.
Topics: Aging; Animals; Aspartic Acid; Brain; Cerebellum; Cerebral Cortex; Creatine; Disease Models, Animal; | 2005 |
MRS of normal and impaired fetal brain development.
Topics: Aging; Aspartic Acid; Brain; Choline; Creatine; Female; Fetal Development; Fetus; gamma-Aminobutyric | 2006 |
Longitudinal changes during aging using proton magnetic resonance spectroscopy.
Topics: Aged; Aged, 80 and over; Aging; Analysis of Variance; Aspartic Acid; Brain; Chi-Square Distribution; | 2006 |
Methods for the diagnosis of creatine deficiency syndromes: a comparative study.
Topics: Adolescent; Aging; Biomarkers; Child; Child, Preschool; Chromatography, High Pressure Liquid; Creati | 2006 |
Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults.
Topics: Aged; Aged, 80 and over; Aging; Body Composition; Creatine; Exercise; Female; Humans; Isometric Cont | 2007 |
Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults.
Topics: Aged; Aged, 80 and over; Aging; Body Composition; Creatine; Exercise; Female; Humans; Isometric Cont | 2007 |
Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults.
Topics: Aged; Aged, 80 and over; Aging; Body Composition; Creatine; Exercise; Female; Humans; Isometric Cont | 2007 |
Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults.
Topics: Aged; Aged, 80 and over; Aging; Body Composition; Creatine; Exercise; Female; Humans; Isometric Cont | 2007 |
Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults.
Topics: Aged; Aged, 80 and over; Aging; Body Composition; Creatine; Exercise; Female; Humans; Isometric Cont | 2007 |
Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults.
Topics: Aged; Aged, 80 and over; Aging; Body Composition; Creatine; Exercise; Female; Humans; Isometric Cont | 2007 |
Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults.
Topics: Aged; Aged, 80 and over; Aging; Body Composition; Creatine; Exercise; Female; Humans; Isometric Cont | 2007 |
Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults.
Topics: Aged; Aged, 80 and over; Aging; Body Composition; Creatine; Exercise; Female; Humans; Isometric Cont | 2007 |
Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults.
Topics: Aged; Aged, 80 and over; Aging; Body Composition; Creatine; Exercise; Female; Humans; Isometric Cont | 2007 |
Prevalence and predictors of cardiac hypertrophy and dysfunction in patients with Type 2 diabetes.
Topics: Aging; Analysis of Variance; Antihypertensive Agents; Cardiomegaly; Creatine; Cross-Sectional Studie | 2008 |
Decrease of NAA with aging outside the seizure focus in mesial temporal lobe epilepsy--a proton-MRS study at 3 Tesla.
Topics: Adolescent; Adult; Aging; Aspartic Acid; Choline; Creatine; Drug Resistance; Epilepsy, Temporal Lobe | 2007 |
Metabolic changes in the normal ageing brain: consistent findings from short and long echo time proton spectroscopy.
Topics: Adolescent; Adult; Aged; Aging; Aspartic Acid; Brain; Choline; Creatine; Female; Humans; Imaging, Th | 2008 |
Long and short echo time proton magnetic resonance spectroscopic imaging of the healthy aging brain.
Topics: Aged; Aged, 80 and over; Aging; Artifacts; Aspartic Acid; Brain; Choline; Creatine; Dipeptides; Fema | 2007 |
Thermal and storage stability of nutraceuticals in a milk beverage dietary supplement.
Topics: Aging; Animals; Beverages; Chondroitin Sulfates; Chromatography, High Pressure Liquid; Creatine; Die | 2007 |
Cardiac structure and function during ageing in energetically compromised Guanidinoacetate N-methyltransferase (GAMT)-knockout mice - a one year longitudinal MRI study.
Topics: Aging; Animals; Creatine; Female; Guanidinoacetate N-Methyltransferase; Heart; Image Processing, Com | 2008 |
Covariates of tramadol disposition in the first months of life.
Topics: Aging; Analgesics, Opioid; Creatine; Cytochrome P-450 CYP2D6; Genotype; Humans; Infant; Infant, Newb | 2008 |
Long-term plasma levels and dose modulation of alacepril in patients with chronic renal failure.
Topics: Aging; Algorithms; Angiotensin-Converting Enzyme Inhibitors; Body Weight; Captopril; Creatine; Creat | 2008 |
Hippocampal neurochemistry, neuromorphometry, and verbal memory in nondemented older adults.
Topics: Aged; Aged, 80 and over; Aging; Aspartic Acid; Creatine; Female; Hippocampus; Humans; Magnetic Reson | 2008 |
Early and sustained alterations in cerebral metabolism after traumatic brain injury in immature rats.
Topics: Aging; Alanine; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Injuries; Cell Respiration; C | 2008 |
The effect of age on the creatine in red cells.
Topics: Aging; Anemia, Hemolytic, Autoimmune; Anemia, Hypochromic; Anemia, Macrocytic; Creatine; Erythrocyte | 1967 |
Compatibility of normal renal function with aging.
Topics: Adult; Aged; Aging; Creatine; Female; Glomerular Filtration Rate; Humans; Kidney; Kidney Function Te | 1967 |
Age-related changes in parathyroid hormone and parathyroid hormone action in normal humans.
Topics: Adult; Aged; Aging; Alkaline Phosphatase; Calcifediol; Calcium; Creatine; Cyclic AMP; Fasting; Femal | 1984 |
The influence of intravenous furosemide on the renal excretion pattern of protein and protein degradation products.
Topics: Aged; Aging; Albuminuria; beta 2-Microglobulin; Creatine; Furosemide; Humans; Hydrogen-Ion Concentra | 1984 |
The effect of physical training in elderly subjects with special reference to energy-rich phosphagens and myoglobin in leg skeletal muscle.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aged; Aging; Blood Glucose; Creatine; Exercise Test; | 1982 |
[Deficiency of amino acid precursors of chemical mediators and of creatine in the aged].
Topics: Acetylcholine; Aged; Aging; Amino Acids; Creatine; Depression; Histamine; Humans; Nicotinic Acids; S | 1981 |
Effect of aging on energy-rich phosphagens in human skeletal muscles.
Topics: Adenine Nucleotides; Aged; Aging; Creatine; Energy Metabolism; Female; Humans; Lactates; Male; Middl | 1980 |
Age-dependent neurotoxicity of striatal lesions produced by aminooxyacetic acid: quantitative in vitro 1H NMR spectroscopic studies.
Topics: Aging; Alanine; Animals; Aspartic Acid; Corpus Striatum; Creatine; Energy Metabolism; gamma-Aminobut | 1995 |
Age dependence of myosin heavy chain transitions induced by creatine depletion in rat skeletal muscle.
Topics: Aging; Animals; Body Weight; Creatine; Female; Guanidines; Male; Muscle, Skeletal; Myofibrils; Myosi | 1995 |
Comparison of the effects of salbutamol and clenbuterol on skeletal muscle mass and carcass composition in senescent rats.
Topics: Adrenergic beta-Agonists; Aging; Albuterol; Animals; Body Composition; Body Weight; Clenbuterol; Cre | 1994 |
Effect of clenbuterol on recovery of muscle mass and carcass protein content following dietary protein depletion in young and old rats.
Topics: Aging; Animals; Body Composition; Body Water; Body Weight; Clenbuterol; Creatine; Creatinine; Dietar | 1994 |
Association between calcium regulatory hormones and other factors and bone mineral density in elderly Chinese men and women.
Topics: 25-Hydroxyvitamin D 2; Aged; Aging; Antihypertensive Agents; Body Mass Index; Bone and Bones; Bone D | 1994 |
Axonal injury and membrane alterations in Alzheimer's disease suggested by in vivo proton magnetic resonance spectroscopic imaging.
Topics: Aged; Aging; Alzheimer Disease; Aspartic Acid; Axons; Brain; Cerebral Cortex; Cerebral Ventricles; C | 1994 |
Effects of age, sex, season and diet on serum ionized calcium, parathyroid hormone and vitamin D in a random population.
Topics: Adult; Aged; Aging; Calcium; Creatine; Diet; Female; Humans; Male; Middle Aged; Parathyroid Hormone; | 1993 |
The concentration of N-acetyl aspartate, creatine + phosphocreatine, and choline in different parts of the brain in adulthood and senium.
Topics: Adult; Aged; Aged, 80 and over; Aging; Aspartic Acid; Brain; Choline; Creatine; Humans; Magnetic Res | 1993 |
Peritoneal equilibration test results are different in infants, children, and adults.
Topics: Adolescent; Adult; Aging; Biological Transport; Child; Child, Preschool; Creatine; Glucose; Humans; | 1995 |
In vivo proton magnetic resonance spectroscopy of the normal aging human brain.
Topics: Adult; Aged; Aging; Body Water; Brain; Choline; Creatine; Glutamic Acid; Glutamine; Humans; Inositol | 1996 |
Parathyroid cell proliferation in the rat: effect of age and of phosphate administration and recovery.
Topics: Aging; Analysis of Variance; Animals; Apoptosis; Biomarkers; Calcitriol; Calcium; Cell Division; Cel | 1996 |
Hippocampal age-related changes in schizophrenia: a proton magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Age Factors; Aging; Aspartic Acid; Choline; Creatine; Female; Functional Laterali | 1996 |
Effect of aging on the rate of muscle protein turnover in rat.
Topics: Aging; Animals; Body Weight; Creatine; Creatinine; DNA; Liver; Longitudinal Studies; Male; Methylhis | 1996 |
Hypertrophy of colonic smooth muscle: structural remodeling, chemical composition, and force output.
Topics: Actins; Adenine Nucleotides; Aging; Animals; Collagen; Colon; Creatine; Creatinine; Elastin; Electri | 1997 |
Metabolite changes with age measured by proton magnetic resonance spectroscopy in normal subjects.
Topics: Adult; Aged; Aging; Aspartic Acid; Brain Mapping; Creatine; Energy Metabolism; Female; Frontal Lobe; | 1997 |
1H-MRS differentiates white matter hyperintensities in subcortical arteriosclerotic encephalopathy from those in normal elderly.
Topics: Aged; Aging; Aspartic Acid; Brain; Choline; Creatine; Humans; Intracranial Arteriosclerosis; Magneti | 1997 |
Altered development of prefrontal neurons in rhesus monkeys with neonatal mesial temporo-limbic lesions: a proton magnetic resonance spectroscopic imaging study.
Topics: Aging; Amygdala; Animals; Animals, Newborn; Aspartic Acid; Biomarkers; Choline; Creatine; Entorhinal | 1997 |
Age-related brain changes in rhesus monkeys: a magnetic resonance spectroscopic study.
Topics: Aging; Animals; Aspartic Acid; Brain; Brain Chemistry; Choline; Cognition; Creatine; Female; Inosito | 1998 |
Calciuria, magnesiuria and creatininuria--relation to age.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Calcium; Child; Child, Preschool; Creatine; Human | 1998 |
Creatine supplementation and age influence muscle metabolism during exercise.
Topics: Adenosine Triphosphate; Adult; Aging; Creatine; Energy Metabolism; Exercise; Female; Food, Fortified | 1998 |
Age-related changes in body composition, hydroxyproline, and creatinine excretion in normal women.
Topics: Absorptiometry, Photon; Adult; Aged; Aged, 80 and over; Aging; Body Composition; Bone and Bones; Bon | 1999 |
In vivo spectroscopic quantification of the N-acetyl moiety, creatine, and choline from large volumes of brain gray and white matter: effects of normal aging.
Topics: Adult; Aged; Aging; Aspartic Acid; Brain Chemistry; Choline; Creatine; Female; Humans; Magnetic Reso | 1999 |
Effects of dietary taurine supplementation or deprivation in aged male Fischer 344 rats.
Topics: Aging; Animals; Blood Urea Nitrogen; Body Weight; Brain; Chromatography, High Pressure Liquid; Creat | 1999 |
MR image segmentation and tissue metabolite contrast in 1H spectroscopic imaging of normal and aging brain.
Topics: Adult; Age Factors; Aged; Aging; Aspartic Acid; Atrophy; Brain; Brain Chemistry; Choline; Creatine; | 1999 |
1H chemical shift imaging of the human brain at age 60-90 years reveals metabolic differences between women and men.
Topics: Aged; Aged, 80 and over; Aging; Aspartic Acid; Blood Glucose; Brain; Choline; Creatine; Energy Metab | 1999 |
In vitro proton and phosphorus NMR spectroscopic analysis of murine (C57Bl/6J) brain development.
Topics: Aging; Animals; Aspartic Acid; Brain; Brain Chemistry; Chloroform; Creatine; gamma-Aminobutyric Acid | 1999 |
A (1)H magnetic resonance spectroscopy study of aging in parietal white matter: implications for trials in multiple sclerosis.
Topics: Adolescent; Adult; Aged; Aging; Aspartic Acid; Brain Chemistry; Choline; Creatine; Female; Humans; I | 2000 |
Protective effect of the energy precursor creatine against toxicity of glutamate and beta-amyloid in rat hippocampal neurons.
Topics: Aging; Amyloid beta-Peptides; Animals; Cells, Cultured; Creatine; Dendrites; Energy Metabolism; Glut | 2000 |
Contribution of prolonged ischemia and donor age to chronic renal allograft dysfunction.
Topics: Aging; Animals; Antigens; Creatine; Cryopreservation; Graft Survival; Ischemia; Kidney; Kidney Trans | 2000 |
Increase in vulnerability of middle-aged rat brain to lead by cerebral energy depletion.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aging; Animals; Astrocytes; Brain; Brain Chemistry; C | 2000 |
Prenatal programming of adult hypertension in the rat.
Topics: Aging; Aldosterone; Animals; Apoptosis; Blood Pressure; Creatine; Dietary Proteins; Female; Fetal Gr | 2001 |
Regional differences and metabolic changes in normal aging of the human brain: proton MR spectroscopic imaging study.
Topics: Adult; Aging; Aspartic Acid; Brain; Choline; Creatine; Female; Humans; Magnetic Resonance Spectrosco | 2001 |
Region and tissue differences of metabolites in normally aged brain using multislice 1H magnetic resonance spectroscopic imaging.
Topics: Aged; Aged, 80 and over; Aging; Analysis of Variance; Aspartic Acid; Brain; Brain Diseases; Choline; | 2001 |
(1)H-MR spectroscopy differentiates mild cognitive impairment from normal brain aging.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Aspartic Acid; Brain Chemistry; Choline; Cognitio | 2001 |
Muscularity as a function of species, sex and age in small mammals.
Topics: Aging; Animals; Body Composition; Creatine; Cricetinae; Female; Guinea Pigs; Male; Mice; Muscle Deve | 1984 |
Quantitative evaluation of cerebral metabolites and cerebral blood flow in patients with carotid stenosis.
Topics: Adult; Aged; Aging; Aspartic Acid; Basal Ganglia; Brain Ischemia; Carotid Stenosis; Cerebral Cortex; | 2001 |
Creatine monohydrate supplemented in swine finishing diets and fresh pork quality: II. Commercial applications.
Topics: Aging; Animal Feed; Animals; Creatine; Dietary Supplements; Food Handling; Food-Processing Industry; | 2001 |
Developmental delay in children: assessment with proton MR spectroscopy.
Topics: Aging; Aspartic Acid; Brain; Child; Child, Preschool; Choline; Creatine; Developmental Disabilities; | 2002 |
[CPK and CT in striated muscles (proceedings)].
Topics: Aging; Animals; Anura; Chickens; Creatine; Creatine Kinase; Humans; Mice; Muscle Contraction; Muscle | 1979 |
[Time course of total creatine during growth and regeneration of striated muscle (proceedings)].
Topics: Aging; Animals; Animals, Newborn; Creatine; Muscle Development; Muscles; Rats; Regeneration | 1979 |
Effect of muscle mass decrease on age-related BMR changes.
Topics: Adult; Aged; Aging; Basal Metabolism; Creatine; Humans; Male; Middle Aged; Muscles; Organ Size; Oxyg | 1977 |
Restitution of ATP and creatine phosphate after experimental depletion in young, adult, and old rats.
Topics: Adenosine Triphosphate; Aging; Animals; Brain; Creatine; Male; Muscles; Myocardium; Phosphocreatine; | 1978 |
The influence of age on renal function and renin and aldosterone responses to sodium-volume expansion and contraction in normotensive and mildly hypertensive humans.
Topics: Adolescent; Adult; Aging; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Creatine; Cross-Se | 1992 |
Preservation of renal function by percutaneous renal angioplasty in high-risk elderly patients: short-term outcome.
Topics: Aged; Aged, 80 and over; Aging; Angioplasty, Balloon; Creatine; Embolism; Female; Humans; Hypertensi | 1992 |
In vivo 1H and 31P NMR spectroscopy of the developing rat brain.
Topics: Adenosine Triphosphate; Aging; Animals; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Hy | 1992 |
Age-dependent changes in cardiac muscle metabolism upon replacement of creatine by beta- guanidinopropionic acid.
Topics: Adenosine Triphosphate; Aging; Animals; Citrate (si)-Synthase; Creatine; Creatine Kinase; Energy Met | 1991 |
Renal function predicts colchicine toxicity: guidelines for the prophylactic use of colchicine in gout.
Topics: Adult; Aged; Aged, 80 and over; Aging; Body Weight; Colchicine; Creatine; Dose-Response Relationship | 1991 |
Age influence on mononuclear phagocyte system Fc-receptor function in poststreptococcal nephritis.
Topics: Adolescent; Adult; Aged; Aging; Child; Chromium Radioisotopes; Creatine; Enzyme-Linked Immunosorbent | 1991 |
Brain development: 1H magnetic resonance spectroscopy of rat brain extracts compared with chromatographic methods.
Topics: Aging; Amino Acids; Animals; Aspartic Acid; Brain; Brain Chemistry; Chromatography, High Pressure Li | 1990 |
Casual urine concentrations of sodium, potassium, and creatine in population studies of blood pressure.
Topics: Adult; Aging; Alcohol Drinking; Blood Pressure; Body Mass Index; Creatine; Humans; Hypertension; Mal | 1990 |
Effect of age on circulating immunoreactive and bioactive parathyroid hormone levels in women.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alkaline Phosphatase; Calcium; Creatine; Female; Humans; Midd | 1987 |
Age-related rise in parathyroid hormone in man: the use of intact and midmolecule antisera to distinguish hormone secretion from retention.
Topics: Adult; Aged; Aged, 80 and over; Aging; Calcium; Creatine; Female; Humans; Hydroxycholecalciferols; I | 1987 |
Energy metabolism in rat brain in vivo studied by 31P nuclear magnetic resonance: changes during postnatal development.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aging; Animals; Animals, Newborn; Brain; Creatine; En | 1986 |
Fractionation of urinary biocolloids in children and adults by gel filtration.
Topics: Adult; Aging; Body Weight; Chemistry Techniques, Analytical; Child; Child, Preschool; Chromatography | 1966 |
[The energy metabolism of skeletal muscle in relation to aging].
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Aging; Animals; Creatine; Energy | 1973 |
Creatine (total creatine).
Topics: Age Factors; Aging; Aorta; Arteries; Arteriosclerosis; Creatine; Creatine Kinase; Humans; Iliac Arte | 1974 |
The variation of urinary oxalate excretion with age.
Topics: Adolescent; Adult; Aged; Aging; Body Surface Area; Carbon Isotopes; Creatine; Female; Humans; Kidney | 1969 |
[Aging of skeletal muscles. Restitution of creatine phosphate of sksletal muscles after work in rats of different ages].
Topics: Age Factors; Aging; Animals; Creatine; Female; Male; Muscles; Phosphocreatine; Physical Exertion; Ra | 1970 |
Estimation of creatine in red cells.
Topics: Aging; Creatine; Erythrocytes; Erythropoiesis; Humans | 1968 |
Decreased restitution of creatine phosphate in white and red skeletal muscles during aging.
Topics: Aging; Animals; Creatine; Female; Male; Muscles; Phosphocreatine; Rats | 1968 |