Page last updated: 2024-10-17

creatine and Aging

creatine has been researched along with Aging in 213 studies

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"Preexercise creatine supplementation may have a beneficial effect on aging muscle performance."9.22Effect of Preexercise Creatine Ingestion on Muscle Performance in Healthy Aging Males. ( Baker, TP; Candow, DG; Farthing, JP, 2016)
"To investigate the effects of creatine supplementation and drop-set resistance training in untrained aging adults."9.22Effect of creatine supplementation and drop-set resistance training in untrained aging adults. ( Brahms, CM; Candow, DG; Johannsmeyer, S; Michel, D; Zello, GA, 2016)
"The supplementation of creatine has shown a marked neuroprotective effect in mouse models of neurodegenerative diseases (Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis)."8.87Creatine in mouse models of neurodegeneration and aging. ( Bender, A; Elstner, M; Klopstock, T, 2011)
" However, there were no associations between NAA/Cr, Glu/Cr, or Gln/Cr and either depression severity or lamotrigine treatment."7.91Lamotrigine Therapy and Biomarkers of Cerebral Energy Metabolism in Older Age Bipolar Depression. ( Forester, BP; Harper, DG; Jensen, E; Mellen, EJ; Ravichandran, C; Silveri, M, 2019)
"Mutations in the creatine (Cr) transporter (CrT) gene lead to cerebral creatine deficiency syndrome-1 (CCDS1), an X-linked metabolic disorder characterized by cerebral Cr deficiency causing intellectual disability, seizures, movement and autistic-like behavioural disturbances, language and speech impairment."7.83A mouse model for creatine transporter deficiency reveals early onset cognitive impairment and neuropathology associated with brain aging. ( Alessandrì, MG; Baroncelli, L; Cacciante, F; Cioni, G; Leuzzi, V; Molinaro, A; Napoli, D; Pizzorusso, T; Putignano, E; Tola, J, 2016)
"To document trends and covariates of creatinemia (Scr) in extremely low birth weight (ELBW, < 1,000 g) neonates, maternal characteristics [betamethasone, premature preterm rupture of membranes (PPROM), pre-eclampsia, maternal Scr], characteristics at delivery [gestational age (GA), birth weight (BW), small for GA (SGA), Apgar, intubation] and during neonatal stay [ventilation, oxygen, parenteral nutrition, ibuprofen, steroids, intraventricular hemorrhage, retinopathy of prematurity (ROP), phototherapy] were linked with Scr observations."7.77Postnatal trends in creatinemia and its covariates in extremely low birth weight (ELBW) neonates. ( Allegaert, K; George, I; Levtchenko, E; Mekahli, D; Rayyan, M, 2011)
"Our objective was to investigate the influence of hypertension on N-acetylaspartate (NAA) and choline (Cho) ratios in brain tissues in a community-dwelling elderly population."7.74N-acetylaspartate/creatine and choline/creatine ratios in the thalami, insular cortex and white matter as markers of hypertension and cognitive impairment in the elderly. ( Aho, SL; Bejot, Y; Ben Salem, D; Brunotte, F; Ricolfi, F; Rouaud, O; Tavernier, B; Walker, PM, 2008)
"In order to establish the degree of renal malfunction necessary for colchicine toxicity in patients receiving it daily for the prevention of recurrent acute gout, we obtained serum creatinine levels and measured or estimated creatinine clearances in a consecutive series of 17 patients with demonstrated colchicine myotoxicity."7.68Renal function predicts colchicine toxicity: guidelines for the prophylactic use of colchicine in gout. ( Duncan, GJ; Kuncl, RW; Singer, JZ; Wallace, SL; Wigley, FM, 1991)
"Creatine is an endogenously produced metabolite, which has the theoretical potential to counteract many of the morphological and metabolic parameters underpinning sarcopenia."6.61Muscular Atrophy and Sarcopenia in the Elderly: Is There a Role for Creatine Supplementation? ( Artioli, GG; Dolan, E; Gualano, B; Pereira, RMR, 2019)
" Emerging evidence now suggests that the timing and dosage of creatine supplementation may be important factors for aging muscle accretion."6.47Sarcopenia: current theories and the potential beneficial effect of creatine application strategies. ( Candow, DG, 2011)
"This is an exploratory trial from the Pro-Elderly study ("Protein Intake and Resistance Training in Aging") aimed at gathering knowledge on the feasibility, safety, and efficacy of co-supplementation with creatine and protein supplementation, combined with resistance training, in older individuals with frailty."5.22Resistance Training and Co-supplementation with Creatine and Protein in Older Subjects with Frailty. ( Collins, J; Gualano, B; Longhurst, G; Roschel, H, 2016)
"Creatine supplementation in close proximity to resistance training may be an important strategy for increasing muscle mass and strength; however, it is unknown whether creatine supplementation before or after resistance training is more effective for aging adults."5.20Strategic creatine supplementation and resistance training in healthy older adults. ( Candow, DG; Farthing, JP; Forbes, SC; Johannsmeyer, S; Vogt, E, 2015)
"Creatine supplementation in conjunction with resistance training (RT) augments gains in lean tissue mass and strength in aging adults; however, there is a large amount of heterogeneity between individual studies that may be related to creatine ingestion strategies."5.12Meta-Analysis Examining the Importance of Creatine Ingestion Strategies on Lean Tissue Mass and Strength in Older Adults. ( Candow, DG; Chilibeck, PD; Forbes, SC; Ostojic, SM; Roberts, MD, 2021)
"The supplementation of creatine has shown a marked neuroprotective effect in mouse models of neurodegenerative diseases (Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis)."4.87Creatine in mouse models of neurodegeneration and aging. ( Bender, A; Elstner, M; Klopstock, T, 2011)
" However, there were no associations between NAA/Cr, Glu/Cr, or Gln/Cr and either depression severity or lamotrigine treatment."3.91Lamotrigine Therapy and Biomarkers of Cerebral Energy Metabolism in Older Age Bipolar Depression. ( Forester, BP; Harper, DG; Jensen, E; Mellen, EJ; Ravichandran, C; Silveri, M, 2019)
" Concentrations of glutamate + glutamin (Glx), cholin (Cho), myoinositol (mIns), N-acetyl aspartate (NAA) expressed as ratio with creatine (Cr) and NAA were correlated with markers of disease activity (RIO score), Multiple Sclerosis Severity Scale (MSSS), Depressive-Severity Status Scale and Simple Numerical Fatigue Scale."3.85Hypothalamic damage in multiple sclerosis correlates with disease activity, disability, depression, and fatigue. ( Baranovičová, E; Bittšanský, M; Čierny, D; Hnilicová, P; Kantorová, E; Kurča, E; Nosáľ, V; Poláček, H; Sivák, Š; Zeleňák, K, 2017)
"Mutations in the creatine (Cr) transporter (CrT) gene lead to cerebral creatine deficiency syndrome-1 (CCDS1), an X-linked metabolic disorder characterized by cerebral Cr deficiency causing intellectual disability, seizures, movement and autistic-like behavioural disturbances, language and speech impairment."3.83A mouse model for creatine transporter deficiency reveals early onset cognitive impairment and neuropathology associated with brain aging. ( Alessandrì, MG; Baroncelli, L; Cacciante, F; Cioni, G; Leuzzi, V; Molinaro, A; Napoli, D; Pizzorusso, T; Putignano, E; Tola, J, 2016)
"In a healthy aging normal population, choline/creatine and myo-inositol/creatine ratios were significantly increased in APOE E4 carriers, suggesting the presence of neuroinflammatory processes and greater membrane turnover in older carriers."3.80APOE genotype modulates proton magnetic resonance spectroscopy metabolites in the aging brain. ( Buthorn, JJ; Christen, E; Conejero-Goldberg, C; Davies, P; Dickinson, D; Goldberg, TE; Gomar, JJ; Gordon, ML; Huet, S; Keehlisen, L; Kingsley, PB; Koppel, J; Uluğ, AM, 2014)
"To document trends and covariates of creatinemia (Scr) in extremely low birth weight (ELBW, < 1,000 g) neonates, maternal characteristics [betamethasone, premature preterm rupture of membranes (PPROM), pre-eclampsia, maternal Scr], characteristics at delivery [gestational age (GA), birth weight (BW), small for GA (SGA), Apgar, intubation] and during neonatal stay [ventilation, oxygen, parenteral nutrition, ibuprofen, steroids, intraventricular hemorrhage, retinopathy of prematurity (ROP), phototherapy] were linked with Scr observations."3.77Postnatal trends in creatinemia and its covariates in extremely low birth weight (ELBW) neonates. ( Allegaert, K; George, I; Levtchenko, E; Mekahli, D; Rayyan, M, 2011)
" We used structural magnetic resonance imaging (sMRI) to measure the volume of the AHC, and magnetic resonance spectroscopy ((1)H-MRS) to measure concentrations of N-acetyl aspartate (NAA), creatine+phosphocreatine (Cr+PCr), myo-inositol (mI) and choline (Cho)."3.76Maturation of limbic regions in Asperger syndrome: a preliminary study using proton magnetic resonance spectroscopy and structural magnetic resonance imaging. ( Baird, G; Bolton, P; Conroy, RM; Curran, S; Daly, E; Foy, C; Hallahan, B; Murphy, DG; Murphy, KC; O'Brien, FM; O'Gorman, RL; Page, L; Robertson, D; Sharma, A, 2010)
"Our objective was to investigate the influence of hypertension on N-acetylaspartate (NAA) and choline (Cho) ratios in brain tissues in a community-dwelling elderly population."3.74N-acetylaspartate/creatine and choline/creatine ratios in the thalami, insular cortex and white matter as markers of hypertension and cognitive impairment in the elderly. ( Aho, SL; Bejot, Y; Ben Salem, D; Brunotte, F; Ricolfi, F; Rouaud, O; Tavernier, B; Walker, PM, 2008)
"Long- and short-echo proton spectroscopic imaging were used to investigate concentrations and R2 relaxation rates of N-acetyl aspartate (NAA) + N-acetyl aspartyl glutamate (NAAG), choline (Cho), creatine (Cr), and myoinositol (mI) in the white matter of the centrum semiovale of 106 healthy volunteers aged 50-90 years; usable data were obtained from 79 subjects."3.74Long and short echo time proton magnetic resonance spectroscopic imaging of the healthy aging brain. ( Charlton, RA; Howe, FA; Markus, HS; McIntyre, DJ, 2007)
"To assess the effect of aging on the proportions of choline (Cho), creatine, and N-acetylaspartate (NAA) in the brains of elderly women and men."3.72Brain changes with aging: MR spectroscopy at supraventricular plane shows differences between women and men. ( Breteler, MM; den Heijer, T; Hofman, A; Origgi, D; Oudkerk, M; Sijens, PE; Vermeer, SE, 2003)
" In megacolon the following occur: 1) structural remodeling expressed as a greater increase in the fraction of maximum force production at short lengths, a shift of optimum length (Lo) to longer lengths, and no change in force per square centimeter; 2) hypertrophy and hyperplasia of both circular and longitudinal muscle; 3) high resting compliance consistent with no disproportionate change in collagen or elastin composition; 4) marked distension so that in situ circumference approximately 1."3.69Hypertrophy of colonic smooth muscle: structural remodeling, chemical composition, and force output. ( Butler, TM; Mooers, SU; Narayan, S; Siegman, MJ; Starcher, BC; Stirewalt, WS; Trinkle-Mulcahy, L, 1997)
" In living adult rhesus monkeys, we studied the long-term effects of early mesial temporo-limbic (MTL) lesions on prefrontal cortex (PFC) neurons using proton magnetic resonance spectroscopic imaging (1H-MRSI), an in vivo neurochemical assay technique for measuring signals from metabolites such as N-acetyl-aspartate (NAA, a neuronal marker), choline-containing compounds (CHO) and creatine + phosphocreatine (CRE)."3.69Altered development of prefrontal neurons in rhesus monkeys with neonatal mesial temporo-limbic lesions: a proton magnetic resonance spectroscopic imaging study. ( Bachevalier, J; Bertolino, A; Frank, JA; Mattay, VS; Saunders, RC; Weinberger, DR, 1997)
"In order to establish the degree of renal malfunction necessary for colchicine toxicity in patients receiving it daily for the prevention of recurrent acute gout, we obtained serum creatinine levels and measured or estimated creatinine clearances in a consecutive series of 17 patients with demonstrated colchicine myotoxicity."3.68Renal function predicts colchicine toxicity: guidelines for the prophylactic use of colchicine in gout. ( Duncan, GJ; Kuncl, RW; Singer, JZ; Wallace, SL; Wigley, FM, 1991)
"Creatine has emerged as a promising neuroprotective agent."2.72Assessing Creatine Supplementation for Neuroprotection against Perinatal Hypoxic-Ischaemic Encephalopathy: A Systematic Review of Perinatal and Adult Pre-Clinical Studies. ( Ellery, SJ; Galinsky, R; Kelly, SB; Snow, RJ; Tran, NT; Walker, DW, 2021)
"Three patients developed renal failure."2.71Long-term outcome of adding mycophenolate mofetil to tacrolimus for nephrotoxicity following liver transplantation. ( Eghtesad, B; Fung, J; Gadomski, M; Jain, A; Marcos, A; Mohanka, R; Vekatramanan, R, 2005)
"Creatine is an endogenously produced metabolite, which has the theoretical potential to counteract many of the morphological and metabolic parameters underpinning sarcopenia."2.61Muscular Atrophy and Sarcopenia in the Elderly: Is There a Role for Creatine Supplementation? ( Artioli, GG; Dolan, E; Gualano, B; Pereira, RMR, 2019)
" Emerging evidence now suggests that the timing and dosage of creatine supplementation may be important factors for aging muscle accretion."2.47Sarcopenia: current theories and the potential beneficial effect of creatine application strategies. ( Candow, DG, 2011)
"Creatine is an inexpensive and safe dietary supplement that has both peripheral and central effects."2.47Use of creatine in the elderly and evidence for effects on cognitive function in young and old. ( Rawson, ES; Venezia, AC, 2011)
"Creatine plays a role in cellular energy metabolism and potentially has a role in protein metabolism."2.41Potential benefits of creatine monohydrate supplementation in the elderly. ( Tarnopolsky, MA, 2000)
"Markers of nocturnal hypoxemia and SDB are associated with cerebral oxidative stress in older people at-risk for dementia, suggesting a potential mechanism by which SDB may contribute to brain degeneration, cognitive decline, and dementia."1.43Association of Anterior Cingulate Glutathione with Sleep Apnea in Older Adults At-Risk for Dementia. ( Cross, N; Duffy, SL; Grunstein, R; Hermens, DF; Hickie, IB; Lagopoulos, J; Lewis, SJ; Mowszowski, L; Naismith, SL; Terpening, Z, 2016)
"Bioenergetic failure is a feature of Alzheimer's disease (AD)."1.40Reduced levels of mitochondrial complex I subunit NDUFB8 and linked complex I + III oxidoreductase activity in the TgCRND8 mouse model of Alzheimer's disease. ( Bazinet, RP; Francis, BM; Gupta, S; Maj, M; Mount, HT; Robinson, B; Song, BJ; Yang, J, 2014)
"CL/F was comparable in ESRD and severe renal impairment."1.40Pharmacokinetics of topiramate in patients with renal impairment, end-stage renal disease undergoing hemodialysis, or hepatic impairment. ( Curtin, CR; Ford, L; Heald, DL; Manitpisitkul, P; Shalayda, K; Wang, SS, 2014)
"Patients with late-life major depressive disorder had a significantly lower NAA/creatine ratio in the left frontal white matter, and higher Cho/creatine and myo-inositol/creatine ratios in the left basal ganglia when compared with the control subjects."1.35Proton magnetic resonance spectroscopy of late-life major depressive disorder. ( Chen, CS; Chiang, IC; Hsieh, TJ; Kuo, YT; Li, CW; Lin, HF; Lin, WC; Liu, GC; Lu, CY, 2009)
"Twenty-four patients with spastic diplegia and twenty-six healthy children were examined."1.35An age and gender dependency of metabolite concentrations in basal ganglia in children with spastic diplegia: proton magnetic resonance spectroscopy study. ( Kubas, B; Kulak, W; Otapowicz, D; Smigielska-Kuzia, J; Sobaniec, W; Zawada, B, 2009)
"Tramadol clearance was described using a two-compartment, zero-order input, first-order elimination linear model."1.35Covariates of tramadol disposition in the first months of life. ( Allegaert, K; Anderson, BJ; de Hoon, JN; Debeer, A; Naulaers, G; Tibboel, D; van den Anker, JN; van Schaik, RH, 2008)
"A rat model of intrauterine growth retardation was employed."1.31Prenatal programming of adult hypertension in the rat. ( Aviles, DH; Manning, J; Vehaskari, VM, 2001)
"5-1 mM was toxic to embryonic hippocampal neurons."1.31Protective effect of the energy precursor creatine against toxicity of glutamate and beta-amyloid in rat hippocampal neurons. ( Brewer, GJ; Wallimann, TW, 2000)
"Taurine is a sulfur amino acid that is present in high concentration in mammalian tissues and previously has been reported to decline in a number of tissues with advancing age."1.30Effects of dietary taurine supplementation or deprivation in aged male Fischer 344 rats. ( Dawson, R; Eppler, B; Liu, S; Patterson, T, 1999)
"Choline was high at birth and declined thereafter."1.28In vivo 1H and 31P NMR spectroscopy of the developing rat brain. ( Hida, K; Kwee, IL; Nakada, T, 1992)
"Creatine was correspondingly increased, but total creatine was unchanged, as were the ATP and the ATP/ADP ratio."1.26Effect of aging on energy-rich phosphagens in human skeletal muscles. ( Bergström, J; Fürst, P; Hellström, K; Möller, P, 1980)

Research

Studies (213)

TimeframeStudies, this research(%)All Research%
pre-199039 (18.31)18.7374
1990's39 (18.31)18.2507
2000's60 (28.17)29.6817
2010's59 (27.70)24.3611
2020's16 (7.51)2.80

Authors

AuthorsStudies
Hone-Blanchet, A1
Bohsali, A1
Krishnamurthy, LC1
Shahid, S1
Lin, Q1
Zhao, L1
Loring, D1
Goldstein, F1
John, SE1
Fleischer, CC1
Levey, A1
Lah, J1
Qiu, D1
Crosson, B1
Forbes, SC5
Ostojic, SM3
Souza-Junior, TP1
Candow, DG10
Tran, NT1
Kelly, SB1
Snow, RJ1
Walker, DW1
Ellery, SJ1
Galinsky, R1
Rodríguez-Nieto, G1
Levin, O2
Hermans, L1
Weerasekera, A1
Sava, AC1
Haghebaert, A1
Huybrechts, A1
Cuypers, K1
Mantini, D1
Himmelreich, U2
Swinnen, SP1
Vints, WAJ1
Ziv, G1
Katkutė, G1
Kušleikienė, S1
Valatkevičienė, K1
Sheoran, S1
Drozdova-Statkevičienė, M1
Gleiznienė, R1
Pääsuke, M1
Dudonienė, V1
Česnaitienė, VJ1
Masiulis, N1
Mahmoudi, N1
Dadak, M2
Bronzlik, P2
Maudsley, AA2
Sheriff, S1
Lanfermann, H2
Ding, XQ2
Dolan, E1
Artioli, GG1
Pereira, RMR1
Gualano, B4
Demnitz, N1
Topiwala, A1
Zsoldos, E1
Stagg, CJ1
Emir, UE2
Johansen-Berg, H1
Ebmeier, KP1
Sexton, CE1
Lyros, E1
Ragoschke-Schumm, A1
Kostopoulos, P1
Sehr, A1
Backens, M1
Kalampokini, S1
Decker, Y1
Lesmeister, M1
Liu, Y1
Reith, W1
Fassbender, K1
Vyssokikh, MY1
Holtze, S1
Averina, OA1
Lyamzaev, KG1
Panteleeva, AA1
Marey, MV1
Zinovkin, RA1
Severin, FF1
Skulachev, MV1
Fasel, N1
Hildebrandt, TB1
Skulachev, VP1
Marshall, RN1
Smeuninx, B1
Morgan, PT1
Breen, L1
McKendry, J1
Currier, BS1
Lim, C1
Mcleod, JC1
Thomas, ACQ1
Phillips, SM2
Deelchand, DK3
McCarten, JR2
Hemmy, LS2
Auerbach, EJ1
Eberly, LE1
Marjańska, M3
Kreider, RB1
Stout, JR1
Roschel, H2
Rawson, ES4
Kirk, B1
Duque, G1
Roberts, MD1
Chilibeck, PD4
Hodges, J1
Grant, A1
Terpstra, M2
Zhao, MM1
Gong, DQ1
Gao, T1
Zhang, L1
Li, JL1
Lv, PA1
Yu, LL1
Gao, F1
Zhou, GH1
Münzer, T1
Schmitz, B1
Wang, X2
Barker, PB3
Pilatus, U1
Kahl, KG1
Yang, JJ1
Jeong, DH1
Lim, YK1
Kougias, DG1
Das, T1
Perez, AB1
Pereira, SL1
Jarak, I1
Almeida, S1
Carvalho, RA1
Sousa, M1
Barros, A1
Alves, MG1
Oliveira, PF1
Cleeland, C1
Pipingas, A1
Scholey, A1
White, D1
Mellen, EJ1
Harper, DG1
Ravichandran, C1
Jensen, E1
Silveri, M1
Forester, BP1
Sporn, L1
MacMillan, EL1
Ge, R1
Greenway, K1
Vila-Rodriguez, F1
Laule, C1
Fried, PJ1
Pascual-Leone, A1
Bolo, NR1
Zhang, X2
Wu, J1
Liu, H1
Chiu, PW1
Mak, HK1
Yau, KK1
Chan, Q1
Chang, RC1
Chu, LW1
Gomar, JJ1
Gordon, ML1
Dickinson, D1
Kingsley, PB1
Uluğ, AM2
Keehlisen, L1
Huet, S1
Buthorn, JJ1
Koppel, J1
Christen, E1
Conejero-Goldberg, C1
Davies, P1
Goldberg, TE1
Souza, WM1
Heck, TG1
Wronski, EC1
Ulbrich, AZ1
Boff, E1
Mori, T1
Mori, K1
Ito, H1
Goji, A1
Miyazaki, M1
Harada, M2
Kurosawa, K1
Kagami, S1
Francis, BM1
Yang, J1
Song, BJ1
Gupta, S1
Maj, M1
Bazinet, RP1
Robinson, B1
Mount, HT1
Moon, A1
Heywood, L1
Rutherford, S1
Cobbold, C1
Ono, K1
Kitagawa, M1
Ito, D1
Tanaka, N1
Watari, T1
Manitpisitkul, P1
Curtin, CR1
Shalayda, K1
Wang, SS1
Ford, L1
Heald, DL1
Abdel-Aziz, K1
Solanky, BS1
Yiannakas, MC1
Altmann, DR1
Wheeler-Kingshott, CA1
Thompson, AJ2
Ciccarelli, O1
Mazgaj, R1
Tal, A1
Goetz, R1
Lazar, M1
Rothman, K1
Messinger, JW1
Malaspina, D1
Gonen, O3
Vogt, E1
Johannsmeyer, S2
Farthing, JP2
Denison, HJ1
Cooper, C1
Sayer, AA1
Robinson, SM1
Vaes, B1
Beke, E1
Truyers, C1
Elli, S1
Buntinx, F1
Verbakel, JY1
Goderis, G1
Van Pottelbergh, G1
Tsili, AC1
Astrakas, LG1
Ntorkou, A1
Giannakis, D1
Stavrou, S1
Maliakas, V1
Sofikitis, N1
Argyropoulou, MI1
Baker, TP1
Duffy, SL1
Lagopoulos, J1
Terpening, Z1
Lewis, SJ1
Grunstein, R1
Mowszowski, L1
Cross, N1
Hermens, DF1
Hickie, IB1
Naismith, SL1
Brandt, AS1
Unschuld, PG1
Pradhan, S1
Lim, IA1
Churchill, G1
Harris, AD1
Hua, J1
Ross, CA1
van Zijl, PC1
Edden, RA1
Margolis, RL1
Collins, J1
Longhurst, G1
Löbel, U1
Hwang, S1
Edwards, A1
Li, Y1
Li, X1
Broniscer, A1
Patay, Z1
Scheer, M1
Bischoff, AM1
Kruzliak, P1
Opatrilova, R1
Bovell, D1
Büsselberg, D1
Baroncelli, L1
Molinaro, A1
Cacciante, F1
Alessandrì, MG1
Napoli, D1
Putignano, E1
Tola, J1
Leuzzi, V1
Cioni, G1
Pizzorusso, T1
Brahms, CM1
Michel, D1
Zello, GA1
Tosato, M1
Marzetti, E1
Cesari, M1
Savera, G1
Miller, RR1
Bernabei, R1
Landi, F2
Calvani, R1
Kantorová, E1
Poláček, H1
Bittšanský, M3
Baranovičová, E1
Hnilicová, P1
Čierny, D1
Sivák, Š1
Nosáľ, V1
Zeleňák, K1
Kurča, E1
Kirov, II2
Fleysher, L1
Fleysher, R1
Patil, V1
Liu, S2
Kulak, W1
Sobaniec, W1
Smigielska-Kuzia, J1
Kubas, B1
Zawada, B1
Otapowicz, D1
Ben Salem, D2
Walker, PM2
Aho, S1
Tavernier, B2
Giroud, M1
Tzourio, C1
Ricolfi, F2
Brunotte, F2
Bejot, Y1
Aho, SL1
Rouaud, O1
Mercimek-Mahmutoglu, S1
Muehl, A1
Salomons, GS1
Neophytou, B1
Moeslinger, D1
Struys, E1
Bodamer, OA1
Jakobs, C1
Stockler-Ipsiroglu, S1
Horská, A1
Farage, L1
Bibat, G1
Nagae, LM1
Kaufmann, WE1
Naidu, S1
Chen, CS1
Chiang, IC1
Li, CW1
Lin, WC1
Lu, CY1
Hsieh, TJ1
Liu, GC1
Lin, HF1
Kuo, YT1
Gybina, AA1
Tkac, I2
Prohaska, JR1
Gu, H1
Pan, Z1
Xi, B1
Hainline, BE1
Shanaiah, N1
Asiago, V1
Gowda, GA1
Raftery, D1
Ronen, I1
Fan, X1
Schettler, S1
Jain, S1
Murray, D1
Kim, DS1
Killiany, R1
Rosene, D1
Jickling, G1
Salam, A1
Mohammad, A1
Hussain, MS1
Scozzafava, J1
Nasser, AM1
Jeerakathil, T1
Shuaib, A1
Camicioli, R1
Onder, G1
Della Vedova, C1
Garcia-Miranda, P1
Garcia-Delgado, M1
Peral, MJ2
Calonge, ML1
Ilundain, AA2
Bemben, MG1
Witten, MS1
Carter, JM1
Eliot, KA1
Knehans, AW1
Bemben, DA1
Raininko, R1
Mattsson, P1
STERN, K1
ASKONAS, BA1
Xu, W1
Zhan, Y1
Huang, W1
Zhang, S1
Lei, H1
O'Brien, FM1
Page, L1
O'Gorman, RL1
Bolton, P1
Sharma, A1
Baird, G1
Daly, E1
Hallahan, B1
Conroy, RM1
Foy, C1
Curran, S1
Robertson, D1
Murphy, KC1
Murphy, DG1
Reyngoudt, H1
Claeys, T1
Vlerick, L1
Verleden, S1
Acou, M1
Deblaere, K1
De Deene, Y1
Audenaert, K1
Goethals, I1
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Robertson, CL1
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Lapides, J1
Zierdt, D1
Marcus, R2
Madvig, P1
Young, G2
Andreasen, F1
Hansen, U1
Husted, SE1
Mogensen, CE1
Möller, P2
Brandt, R1
Santagostino, A1
Bergström, J1
Fürst, P1
Hellström, K1
Chang, C1
Jang, T1
Mulkerrin, E1
Epstein, FH1
Clark, BA1
Adams, GR1
Baldwin, KM1
Charles, HC1
Lazeyras, F1
Krishnan, KR1
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Doraiswamy, PM1
McDonald, WM1
Carter, WJ2
Lynch, ME2
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MacDonald, D1
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Henriksen, O1
Mendley, SR1
Majkowski, NL1
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Poland, RE1
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Wang, Q1
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Clarkson, PM1
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Tullius, SG1
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Jonas, S1
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Volk, HD1
Neuhaus, P1
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Arendt, T1
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Grachev, ID2
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Pelliccioli, GP1
Piccirilli, M1
Gobbi, G1
Senin, U1
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Rahlmann, DF1
Smith, AH1
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Stahl, CA1
Allee, GL1
Berg, EP1
Filippi, CG1
Deck, MD1
Zimmerman, RD1
Heier, LA1
Maréchal, G2
Plaghki, L2
Colson-Van Schoor, M1
Tzankoff, SP1
McNamara, MC1
Miller, AT1
Shen, AL1
Wood, JJ1
Luft, FC1
Fineberg, NS1
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O'Donovan, RM1
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Simon, LS1
Basch, CM1
Young, DY1
Robinson, DR1
Hida, K1
Kwee, IL1
Nakada, T1
Kawabe, H1
Furukawa, T1
Takenaka, T1
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Clinical Trials (11)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Creatine Supplementation and Resistance Training in Patients With Breast Cancer (CaRTiC Study)[NCT05878106]120 participants (Anticipated)Interventional2024-01-08Not yet recruiting
The Effect of Creatine Monohydrate on Persistent Post-concussive Symptoms - a Pilot Study Protocol[NCT05562232]45 participants (Anticipated)Interventional2022-10-01Not yet recruiting
Effects of Creatine and Caffeine Co-Supplementation on Muscle Mass and Muscle Performance in Trained Young Adults[NCT04290819]36 participants (Anticipated)Interventional2019-02-15Recruiting
Project Arthritis Recovering Quality of Life Through Education 70+[NCT04058002]34 participants (Anticipated)Interventional2019-08-15Not yet recruiting
Different Protein and Derivatives Supplementation Strategies Combined With Resistance Training in Pre-frail and Frail Elderly[NCT01890382]200 participants (Actual)Interventional2015-10-01Completed
Sarcopenia and Risk of Fall in Elder Post-menopausal Osteoporotic Women: a Pilot Study[NCT03382366]40 participants (Anticipated)Interventional2017-03-29Recruiting
Prematurity as Predictor of Children's Cardiovascular-renal Health (PREMATCH)[NCT02147457]180 participants (Actual)Observational2014-10-31Completed
The Effects of PeakATP (Adenosine 5' - Triphosphate Disodium) Supplementation vs. Placebo on Measures of Mood, Reaction Time and Cognitive Performance[NCT05100589]35 participants (Actual)Interventional2021-10-06Completed
Creatine Monohydrate and Conjugated Linoleic Acid Improve Strength and Body Composition Following Resistance Exercise in Older Adults[NCT00473902]39 participants (Actual)Interventional2003-08-31Completed
Exercise and Nutritional Supplementation for Aging and Sedentary Lifestyles[NCT03536871]45 participants (Actual)Interventional2018-05-01Completed
Effect of Conjugated Linoleic Acid Associated With Aerobic Exercise on Body Fat and Lipid Profile in Obese Women: A Randomized, Double-blinded and Placebo-controlled Trial[NCT02529046]28 participants (Actual)Interventional2007-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

31 reviews available for creatine and Aging

ArticleYear
Assessing Creatine Supplementation for Neuroprotection against Perinatal Hypoxic-Ischaemic Encephalopathy: A Systematic Review of Perinatal and Adult Pre-Clinical Studies.
    Cells, 2021, 10-27, Volume: 10, Issue:11

    Topics: Aging; Animals; Creatine; Dietary Supplements; Female; Hypoxia-Ischemia, Brain; Male; Neuroprotectio

2021
Muscular Atrophy and Sarcopenia in the Elderly: Is There a Role for Creatine Supplementation?
    Biomolecules, 2019, 10-23, Volume: 9, Issue:11

    Topics: Aged; Aging; Animals; Creatine; Dietary Supplements; Exercise; Humans; Muscular Atrophy

2019
Nutritional Strategies to Offset Disuse-Induced Skeletal Muscle Atrophy and Anabolic Resistance in Older Adults: From Whole-Foods to Isolated Ingredients.
    Nutrients, 2020, May-25, Volume: 12, Issue:5

    Topics: Aged; Aging; Creatine; Diet, High-Protein; Dietary Proteins; Dietary Supplements; Exercise; Fatty Ac

2020
Nutritional Supplements to Support Resistance Exercise in Countering the Sarcopenia of Aging.
    Nutrients, 2020, Jul-10, Volume: 12, Issue:7

    Topics: Aged; Aging; Creatine; Diet; Dietary Proteins; Dietary Supplements; Exercise; Fatty Acids, Omega-3;

2020
Creatine in Health and Disease.
    Nutrients, 2021, Jan-29, Volume: 13, Issue:2

    Topics: Aging; Biological Availability; Chronic Disease; Creatine; Dietary Supplements; Humans; Wounds and I

2021
Creatine in Health and Disease.
    Nutrients, 2021, Jan-29, Volume: 13, Issue:2

    Topics: Aging; Biological Availability; Chronic Disease; Creatine; Dietary Supplements; Humans; Wounds and I

2021
Creatine in Health and Disease.
    Nutrients, 2021, Jan-29, Volume: 13, Issue:2

    Topics: Aging; Biological Availability; Chronic Disease; Creatine; Dietary Supplements; Humans; Wounds and I

2021
Creatine in Health and Disease.
    Nutrients, 2021, Jan-29, Volume: 13, Issue:2

    Topics: Aging; Biological Availability; Chronic Disease; Creatine; Dietary Supplements; Humans; Wounds and I

2021
Creatine Supplementation and Brain Health.
    Nutrients, 2021, 02-10, Volume: 13, Issue:2

    Topics: Aging; Alzheimer Disease; Blood-Brain Barrier; Brain; Brain Concussion; Brain Injuries; Cognition; C

2021
Current Evidence and Possible Future Applications of Creatine Supplementation for Older Adults.
    Nutrients, 2021, Feb-26, Volume: 13, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Bone Density; Creatine; Dietary Supplements; Exercise; Female; Human

2021
Meta-Analysis Examining the Importance of Creatine Ingestion Strategies on Lean Tissue Mass and Strength in Older Adults.
    Nutrients, 2021, Jun-02, Volume: 13, Issue:6

    Topics: Aged; Aging; Creatine; Dietary Supplements; Eating; Food, Fortified; Humans; Muscle Strength; Muscle

2021
[Doping with illegal and legal substances in old age].
    Zeitschrift fur Gerontologie und Geriatrie, 2018, Volume: 51, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Creatine; Doping in Sports; Female; Humans; Illi

2018
A role for nutritional intervention in addressing the aging neuromuscular junction.
    Nutrition research (New York, N.Y.), 2018, 02-17, Volume: 53

    Topics: Aging; Creatine; Diet; Dietary Proteins; Dietary Supplements; Fatty Acids, Omega-3; Humans; Muscle,

2018
Neurochemical changes in the aging brain: A systematic review.
    Neuroscience and biobehavioral reviews, 2019, Volume: 98

    Topics: Aging; Alzheimer Disease; Animals; Brain; Choline; Cognition; Creatine; Humans

2019
Creatine supplementation and aging musculoskeletal health.
    Endocrine, 2014, Volume: 45, Issue:3

    Topics: Aging; Creatine; Humans; Osteoporosis; Resistance Training; Sarcopenia

2014
Creatine supplementation: can it improve quality of life in the elderly without associated resistance training?
    Current aging science, 2013, Volume: 6, Issue:3

    Topics: Activities of Daily Living; Age Factors; Aged; Aging; Anabolic Agents; Creatine; Dietary Supplements

2013
Prevention and optimal management of sarcopenia: a review of combined exercise and nutrition interventions to improve muscle outcomes in older people.
    Clinical interventions in aging, 2015, Volume: 10

    Topics: Aged; Aging; Creatine; Diet; Dietary Proteins; Dietary Supplements; Exercise; Exercise Therapy; Huma

2015
Nutritional supplements in support of resistance exercise to counter age-related sarcopenia.
    Advances in nutrition (Bethesda, Md.), 2015, Volume: 6, Issue:4

    Topics: Aged; Aging; Creatine; Diet; Dietary Proteins; Dietary Supplements; Fatty Acids, Omega-3; Female; Hu

2015
Creatine supplementation in the aging population: effects on skeletal muscle, bone and brain.
    Amino acids, 2016, Volume: 48, Issue:8

    Topics: Aged, 80 and over; Aging; Bone and Bones; Brain; Creatine; Dietary Supplements; Female; Humans; Male

2016
Creatine supplementation in the aging population: effects on skeletal muscle, bone and brain.
    Amino acids, 2016, Volume: 48, Issue:8

    Topics: Aged, 80 and over; Aging; Bone and Bones; Brain; Creatine; Dietary Supplements; Female; Humans; Male

2016
Creatine supplementation in the aging population: effects on skeletal muscle, bone and brain.
    Amino acids, 2016, Volume: 48, Issue:8

    Topics: Aged, 80 and over; Aging; Bone and Bones; Brain; Creatine; Dietary Supplements; Female; Humans; Male

2016
Creatine supplementation in the aging population: effects on skeletal muscle, bone and brain.
    Amino acids, 2016, Volume: 48, Issue:8

    Topics: Aged, 80 and over; Aging; Bone and Bones; Brain; Creatine; Dietary Supplements; Female; Humans; Male

2016
Measurement of muscle mass in sarcopenia: from imaging to biochemical markers.
    Aging clinical and experimental research, 2017, Volume: 29, Issue:1

    Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Aging; Anthropometry; Biomarkers; Body Composition;

2017
Validated treatments and therapeutics prospectives regarding pharmacological products for sarcopenia.
    The journal of nutrition, health & aging, 2009, Volume: 13, Issue:8

    Topics: Aged; Aging; Anabolic Agents; Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Cr

2009
Potential of creatine supplementation for improving aging bone health.
    The journal of nutrition, health & aging, 2010, Volume: 14, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Bone Density; Creatine; Dietary Supplements; Female; Humans; Male; M

2010
Sarcopenia: current theories and the potential beneficial effect of creatine application strategies.
    Biogerontology, 2011, Volume: 12, Issue:4

    Topics: Aged; Aging; Creatine; Dietary Supplements; Humans; Middle Aged; Muscle Proteins; Muscle Strength; M

2011
Creatine in mouse models of neurodegeneration and aging.
    Amino acids, 2011, Volume: 40, Issue:5

    Topics: Aging; Animals; Creatine; Disease Models, Animal; Humans; Mice; Neurodegenerative Diseases; Rejuvena

2011
Use of creatine in the elderly and evidence for effects on cognitive function in young and old.
    Amino acids, 2011, Volume: 40, Issue:5

    Topics: Aging; Cognition; Creatine; Dietary Supplements; Humans

2011
Metabolic agents that enhance ATP can improve cognitive functioning: a review of the evidence for glucose, oxygen, pyruvate, creatine, and L-carnitine.
    Nutrients, 2011, Volume: 3, Issue:8

    Topics: Adenosine Triphosphate; Aging; Brain; Carnitine; Cognition; Cognition Disorders; Creatine; Energy Me

2011
HUMAN BIOLOGY AND RESEARCH IN BODY COMPOSITION.
    Annals of the New York Academy of Sciences, 1963, Sep-26, Volume: 110

    Topics: Aging; Body Composition; Bone and Bones; Creatine; Creatinine; Humans; Minerals; Muscles; Tooth; Uri

1963
[PHYSIOPATHOLOGICAL AND CLINICAL ASPECTS OF THERAPY IN THE AGED PATIENT].
    Giornale di gerontologia. Supplemento, 1964, Volume: 60

    Topics: Absorption; Aging; Blood; Cinnamates; Creatine; Creatinine; Drug Therapy; Geriatrics; Humans; Pharma

1964
N-acetylaspartate as a marker of neuronal injury in neurodegenerative disease.
    Advances in experimental medicine and biology, 2006, Volume: 576

    Topics: Aging; Alcoholism; Amyotrophic Lateral Sclerosis; Aspartic Acid; Biomarkers; Brain; Brain Injuries;

2006
Stimulation of skin's energy metabolism provides multiple benefits for mature human skin.
    BioFactors (Oxford, England), 2005, Volume: 25, Issue:1-4

    Topics: Administration, Topical; Adult; Aging; Coenzymes; Creatine; Energy Metabolism; Humans; Middle Aged;

2005
The potential benefits of creatine and conjugated linoleic acid as adjuncts to resistance training in older adults.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2008, Volume: 33, Issue:1

    Topics: Aged; Aging; Creatine; Exercise; Humans; Linoleic Acids, Conjugated; Muscular Atrophy; Physical Fitn

2008
Potential benefits of creatine monohydrate supplementation in the elderly.
    Current opinion in clinical nutrition and metabolic care, 2000, Volume: 3, Issue:6

    Topics: Aged; Aging; Creatine; Dietary Supplements; Exercise; Humans; Muscle, Skeletal; Proteins; Sports

2000
Renal biochemistry in rheumatic disease.
    Bailliere's clinical rheumatology, 1988, Volume: 2, Issue:1

    Topics: Aging; Anti-Inflammatory Agents, Non-Steroidal; Biomechanical Phenomena; Blood Chemical Analysis; Cr

1988
Transitional nephrology.
    The Urologic clinics of North America, 1985, Volume: 12, Issue:1

    Topics: Adult; Aging; Animals; Blood Urea Nitrogen; Child; Child, Preschool; Creatine; Embryonic and Fetal D

1985

Trials

17 trials available for creatine and Aging

ArticleYear
Strategic creatine supplementation and resistance training in healthy older adults.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2015, Volume: 40, Issue:7

    Topics: Absorptiometry, Photon; Aged; Aging; Body Composition; Creatine; Dietary Supplements; Double-Blind M

2015
Effect of Preexercise Creatine Ingestion on Muscle Performance in Healthy Aging Males.
    Journal of strength and conditioning research, 2016, Volume: 30, Issue:6

    Topics: Aging; Creatine; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Exercise; Humans; Mal

2016
Resistance Training and Co-supplementation with Creatine and Protein in Older Subjects with Frailty.
    The Journal of frailty & aging, 2016, Volume: 5, Issue:2

    Topics: Absorptiometry, Photon; Aged; Aging; Body Composition; Creatine; Dietary Supplements; Double-Blind M

2016
Effect of creatine supplementation and drop-set resistance training in untrained aging adults.
    Experimental gerontology, 2016, Volume: 83

    Topics: Aging; Body Composition; Canada; Creatine; Diet; Dietary Supplements; Double-Blind Method; Female; H

2016
The effects of supplementation with creatine and protein on muscle strength following a traditional resistance training program in middle-aged and older men.
    The journal of nutrition, health & aging, 2010, Volume: 14, Issue:2

    Topics: Aged; Aging; Body Composition; Creatine; Dietary Proteins; Dietary Supplements; Double-Blind Method;

2010
The aging hippocampus: cognitive, biochemical and structural findings.
    Cerebral cortex (New York, N.Y. : 1991), 2003, Volume: 13, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aging; Aspartic Acid; Choline; Cognition; Creatine; Female; Hippocam

2003
Long-term outcome of adding mycophenolate mofetil to tacrolimus for nephrotoxicity following liver transplantation.
    Transplantation, 2005, Sep-27, Volume: 80, Issue:6

    Topics: Adult; Aged; Aging; Creatine; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kidney Fu

2005
Reduced renal response to low-dose dopamine infusion in the elderly.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1995, Volume: 50, Issue:5

    Topics: Adult; Aged; Aging; Creatine; Diuresis; Dopamine; Dose-Response Relationship, Drug; Humans; Infusion

1995
Proton spectroscopy of human brain: effects of age and sex.
    Progress in neuro-psychopharmacology & biological psychiatry, 1994, Volume: 18, Issue:6

    Topics: Adult; Aged; Aging; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Female; Humans; Magnet

1994
Effects of creatine monohydrate ingestion in sedentary and weight-trained older adults.
    Acta physiologica Scandinavica, 1998, Volume: 164, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Anthropometry; Creatine; Diet; Exercise; Female; Humans; Male; Muscl

1998
Acute creatine supplementation in older men.
    International journal of sports medicine, 2000, Volume: 21, Issue:1

    Topics: Aged; Aging; Body Composition; Creatine; Dietary Supplements; Exercise; Humans; Male; Middle Aged; M

2000
Aging alters regional multichemical profile of the human brain: an in vivo 1H-MRS study of young versus middle-aged subjects.
    Journal of neurochemistry, 2001, Volume: 76, Issue:2

    Topics: Adult; Age Factors; Aging; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Female; gamma-A

2001
Aging alters the multichemical networking profile of the human brain: an in vivo (1)H-MRS study of young versus middle-aged subjects.
    Journal of neurochemistry, 2001, Volume: 77, Issue:1

    Topics: Adult; Aging; Analysis of Variance; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Female

2001
Neuromuscular properties and fatigue in older men following acute creatine supplementation.
    European journal of applied physiology, 2001, Volume: 84, Issue:4

    Topics: Aged; Aged, 80 and over; Aging; Creatine; Elbow Joint; Electromyography; Humans; Male; Muscle Contra

2001
Effects of oral creatine supplementation on maximal pedalling performance in older adults.
    European journal of applied physiology, 2001, Volume: 84, Issue:6

    Topics: Administration, Oral; Adult; Aged; Aging; Creatine; Exercise; Exercise Test; Heart Rate; Humans; Mal

2001
Effects of naproxen on renal function in older patients with mild to moderate renal dysfunction.
    British journal of rheumatology, 1992, Volume: 31, Issue:3

    Topics: Aged; Aging; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Creatine; Dinoprostone; Dose-R

1992
Importance of the renin-angiotensin system in sodium regulation in essential hypertension.
    American journal of hypertension, 1991, Volume: 4, Issue:2 Pt 1

    Topics: Adult; Aging; Arginine Vasopressin; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Creatine

1991

Other Studies

165 other studies available for creatine and Aging

ArticleYear
Relationships between frontal metabolites and Alzheimer's disease biomarkers in cognitively normal older adults.
    Neurobiology of aging, 2022, Volume: 109

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Aspartic Acid; Biomarkers; Cognition; Creatine; Fem

2022
A High Dose of Creatine Combined with Resistance Training Appears to Be Required to Augment Indices of Bone Health in Older Adults.
    Annals of nutrition & metabolism, 2022, Volume: 78, Issue:3

    Topics: Aged; Aging; Bone and Bones; Bone Density; Creatine; Dietary Supplements; Double-Blind Method; Human

2022
Organization of neurochemical interactions in young and older brains as revealed with a network approach: Evidence from proton magnetic resonance spectroscopy (
    NeuroImage, 2023, 02-01, Volume: 266

    Topics: Aged; Aging; Aspartic Acid; Brain; Choline; Creatine; Humans; Inositol; Motor Cortex; Prefrontal Cor

2023
Neurometabolic correlates of posturography in normal aging and older adults with mild cognitive impairment: Evidence from a
    NeuroImage. Clinical, 2023, Volume: 37

    Topics: Aged; Aging; Aspartic Acid; Choline; Cognitive Dysfunction; Creatine; Glutamine; Humans; Inositol; P

2023
Microstructural and Metabolic Changes in Normal Aging Human Brain Studied with Combined Whole-Brain MR Spectroscopic Imaging and Quantitative MR Imaging.
    Clinical neuroradiology, 2023, Volume: 33, Issue:4

    Topics: Aging; Aspartic Acid; Brain; Choline; Creatine; Humans; Inositol; Magnetic Resonance Imaging; Magnet

2023
Alcohol consumption is associated with reduced creatine levels in the hippocampus of older adults.
    Psychiatry research. Neuroimaging, 2020, 01-30, Volume: 295

    Topics: Aged; Aging; Alcohol Drinking; Cohort Studies; Creatine; Female; Hippocampus; Humans; Magnetic Reson

2020
Normal brain aging and Alzheimer's disease are associated with lower cerebral pH: an in vivo histidine
    Neurobiology of aging, 2020, Volume: 87

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Brain; Cognitive Dysfunction; Creatine; De

2020
Mild depolarization of the inner mitochondrial membrane is a crucial component of an anti-aging program.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 03-24, Volume: 117, Issue:12

    Topics: Adenosine Diphosphate; Aging; Animals; Chiroptera; Creatine; Electron Transport; Embryo, Mammalian;

2020
Changes in the intracellular microenvironment in the aging human brain.
    Neurobiology of aging, 2020, Volume: 95

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Aspartic Acid; Brain; Brain Chemistry; Cellular M

2020
Region-specific aging of the human brain as evidenced by neurochemical profiles measured noninvasively in the posterior cingulate cortex and the occipital lobe using
    Neuroscience, 2017, 06-23, Volume: 354

    Topics: Aged; Aged, 80 and over; Aging; Ascorbic Acid; Aspartic Acid; Brain Chemistry; Creatine; Dipeptides;

2017
In ovo feeding of creatine pyruvate modulates growth performance, energy reserves and mRNA expression levels of gluconeogenesis and glycogenesis enzymes in liver of embryos and neonatal broilers.
    Journal of animal physiology and animal nutrition, 2018, Volume: 102, Issue:2

    Topics: Aging; Animals; Chick Embryo; Chickens; Creatine; Gene Expression Regulation, Developmental; Gene Ex

2018
Effects of Aging on the Human Brain: A Proton and Phosphorus MR Spectroscopy Study at 3T.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2018, Volume: 28, Issue:4

    Topics: Adult; Aged; Aging; Biomarkers; Brain; Choline; Creatine; Female; Gray Matter; Humans; Magnetic Reso

2018
Blood Chemistry Reference Values for Free-Ranging Asiatic Black Bears ( Ursus thibetanus) by Season, Age, and Sex.
    Journal of wildlife diseases, 2018, Volume: 54, Issue:3

    Topics: Aging; Ammonia; Animals; Bilirubin; Blood Glucose; Blood Urea Nitrogen; Cholesterol; Creatine; Femal

2018
Senescence and declining reproductive potential: Insight into molecular mechanisms through testicular metabolomics.
    Biochimica et biophysica acta. Molecular basis of disease, 2018, Volume: 1864, Issue:10

    Topics: Aging; Animals; Betaine; Creatine; Fertility; Glutathione; Magnetic Resonance Spectroscopy; Male; Me

2018
Lamotrigine Therapy and Biomarkers of Cerebral Energy Metabolism in Older Age Bipolar Depression.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2019, Volume: 27, Issue:8

    Topics: Aged; Aging; Antipsychotic Agents; Aspartic Acid; Biomarkers; Bipolar Disorder; Cerebral Cortex; Cre

2019
Longer Repetition Time Proton MR Spectroscopy Shows Increasing Hippocampal and Parahippocampal Metabolite Concentrations with Aging.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2019, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Aging; Aspartic Acid; Choline; Creatine; Female; Glutamic Acid; Glutamine; Hippoc

2019
Diabetes and the link between neuroplasticity and glutamate in the aging human motor cortex.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2019, Volume: 130, Issue:9

    Topics: Aged; Aged, 80 and over; Aging; Aspartic Acid; Creatine; Diabetes Mellitus, Type 2; Female; Glucose;

2019
Age- and gender-related metabonomic alterations in striatum and cerebellar cortex in rats.
    Brain research, 2013, Apr-24, Volume: 1507

    Topics: Aging; Animals; Cerebellar Cortex; Corpus Striatum; Creatine; Female; Glutamic Acid; Inositol; Lacti

2013
Metabolic changes in the anterior and posterior cingulate cortices of the normal aging brain: proton magnetic resonance spectroscopy study at 3 T.
    Age (Dordrecht, Netherlands), 2014, Volume: 36, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Aspartic Acid; Brain Chemistry; China; Choline; Creatine; Fem

2014
APOE genotype modulates proton magnetic resonance spectroscopy metabolites in the aging brain.
    Biological psychiatry, 2014, May-01, Volume: 75, Issue:9

    Topics: Aged; Aged, 80 and over; Aging; Apolipoprotein E3; Apolipoprotein E4; Apolipoproteins E; Brain; Chol

2014
Effects of creatine supplementation on biomarkers of hepatic and renal function in young trained rats.
    Toxicology mechanisms and methods, 2013, Volume: 23, Issue:9

    Topics: Aging; Anabolic Agents; Animals; Biomarkers; Creatine; Kidney; Kidney Function Tests; Liver; Liver F

2013
Age-related changes in a patient with Pelizaeus-Merzbacher disease determined by repeated 1H-magnetic resonance spectroscopy.
    Journal of child neurology, 2014, Volume: 29, Issue:2

    Topics: Aging; Aspartic Acid; Case-Control Studies; Child, Preschool; Creatine; gamma-Aminobutyric Acid; Glu

2014
Faster metabolite (1)H transverse relaxation in the elder human brain.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Adolescent; Aged; Aged, 80 and over; Aging; Aspartic Acid; Cellular Microenvironment; Choline; Creat

2013
Reduced levels of mitochondrial complex I subunit NDUFB8 and linked complex I + III oxidoreductase activity in the TgCRND8 mouse model of Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2014, Volume: 39, Issue:2

    Topics: Adenosine Triphosphate; Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cardiolip

2014
Regional variations and age-related changes detected with magnetic resonance spectroscopy in the brain of healthy dogs.
    American journal of veterinary research, 2014, Volume: 75, Issue:2

    Topics: Aging; Animals; Aspartic Acid; Brain; Choline; Creatine; Dogs; Female; Lactic Acid; Magnetic Resonan

2014
Pharmacokinetics of topiramate in patients with renal impairment, end-stage renal disease undergoing hemodialysis, or hepatic impairment.
    Epilepsy research, 2014, Volume: 108, Issue:5

    Topics: Adult; Aged; Aging; Anticonvulsants; Creatine; Female; Fructose; Humans; Kidney Failure, Chronic; Li

2014
Age related changes in metabolite concentrations in the normal spinal cord.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Adult; Age Factors; Aged; Aging; Aspartic Acid; Choline; Creatine; Female; Glutamic Acid; Glutamine;

2014
Hypo-metabolism of the rostral anterior cingulate cortex associated with working memory impairment in 18 cases of schizophrenia.
    Brain imaging and behavior, 2016, Volume: 10, Issue:1

    Topics: Adult; Aging; Aspartic Acid; Creatine; Female; Gliosis; Gyrus Cinguli; Humans; Inositol; Intelligenc

2016
The correlation between blood pressure and kidney function decline in older people: a registry-based cohort study.
    BMJ open, 2015, Jun-30, Volume: 5, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Belgium; Blood Pressure; Comorbidity; Creatine; Glomerular Filtratio

2015
MR Spectra of Normal Adult Testes and Variations with Age: Preliminary Observations.
    European radiology, 2016, Volume: 26, Issue:7

    Topics: Adult; Age Factors; Aged; Aging; Choline; Creatine; Humans; Inositol; Magnetic Resonance Spectroscop

2016
Association of Anterior Cingulate Glutathione with Sleep Apnea in Older Adults At-Risk for Dementia.
    Sleep, 2016, Apr-01, Volume: 39, Issue:4

    Topics: Aged; Aging; Biomarkers; Cognition Disorders; Cognitive Dysfunction; Creatine; Dementia; Depression;

2016
Age-related changes in anterior cingulate cortex glutamate in schizophrenia: A (1)H MRS Study at 7 Tesla.
    Schizophrenia research, 2016, Volume: 172, Issue:1-3

    Topics: Adult; Aging; Antipsychotic Agents; Aspartic Acid; Choline; Creatine; Dipeptides; Female; gamma-Amin

2016
Discrepant longitudinal volumetric and metabolic evolution of diffuse intrinsic Pontine gliomas during treatment: implications for current response assessment strategies.
    Neuroradiology, 2016, Volume: 58, Issue:10

    Topics: Adolescent; Aging; Aspartic Acid; Biomarkers, Tumor; Brain Stem; Brain Stem Neoplasms; Child; Child,

2016
Creatine and creatine pyruvate reduce hypoxia-induced effects on phrenic nerve activity in the juvenile mouse respiratory system.
    Experimental and molecular pathology, 2016, Volume: 101, Issue:1

    Topics: Aging; Animals; Creatine; Hypoxia; Mice; Motor Activity; Phrenic Nerve; Pyruvic Acid; Respiratory Sy

2016
A mouse model for creatine transporter deficiency reveals early onset cognitive impairment and neuropathology associated with brain aging.
    Human molecular genetics, 2016, 10-01, Volume: 25, Issue:19

    Topics: Aging; Animals; Brain; Brain Diseases, Metabolic, Inborn; Cognitive Dysfunction; Creatine; Disease M

2016
Hypothalamic damage in multiple sclerosis correlates with disease activity, disability, depression, and fatigue.
    Neurological research, 2017, Volume: 39, Issue:4

    Topics: Adult; Aging; Aspartic Acid; Case-Control Studies; Choline; Creatine; Cross-Sectional Studies; Depre

2017
Age dependence of regional proton metabolites T2 relaxation times in the human brain at 3 T.
    Magnetic resonance in medicine, 2008, Volume: 60, Issue:4

    Topics: Adult; Aged; Aging; Aspartic Acid; Brain; Choline; Creatine; Female; Humans; Magnetic Resonance Spec

2008
An age and gender dependency of metabolite concentrations in basal ganglia in children with spastic diplegia: proton magnetic resonance spectroscopy study.
    Journal of child neurology, 2009, Volume: 24, Issue:1

    Topics: Adolescent; Aging; Aspartic Acid; Basal Ganglia; Case-Control Studies; Cerebral Palsy; Child; Child,

2009
Brain flexibility and balance and gait performances mark morphological and metabolic abnormalities in the elderly.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2008, Volume: 15, Issue:12

    Topics: Aged; Aged, 80 and over; Aging; Aspartic Acid; Brain; Choline; Community Health Planning; Creatine;

2008
N-acetylaspartate/creatine and choline/creatine ratios in the thalami, insular cortex and white matter as markers of hypertension and cognitive impairment in the elderly.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Aspartic Acid; Biomarkers; Cerebral Cortex; Choline; Cognition Disor

2008
Screening for X-linked creatine transporter (SLC6A8) deficiency via simultaneous determination of urinary creatine to creatinine ratio by tandem mass-spectrometry.
    Molecular genetics and metabolism, 2009, Volume: 96, Issue:4

    Topics: Adolescent; Age Distribution; Aging; Child; Child, Preschool; Creatine; Creatinine; Female; Genes, X

2009
Brain metabolism in Rett syndrome: age, clinical, and genotype correlations.
    Annals of neurology, 2009, Volume: 65, Issue:1

    Topics: Adolescent; Aging; Analysis of Variance; Aspartic Acid; Case-Control Studies; Child; Child, Preschoo

2009
Proton magnetic resonance spectroscopy of late-life major depressive disorder.
    Psychiatry research, 2009, Jun-30, Volume: 172, Issue:3

    Topics: Aged; Aging; Aspartic Acid; Basal Ganglia; Biomarkers; Brain; Choline; Cognition; Creatine; Depressi

2009
Copper deficiency alters the neurochemical profile of developing rat brain.
    Nutritional neuroscience, 2009, Volume: 12, Issue:3

    Topics: Aging; Animals; Ascorbic Acid; Aspartic Acid; Brain; Brain Chemistry; Cerebellum; Citric Acid; Coppe

2009
1H NMR metabolomics study of age profiling in children.
    NMR in biomedicine, 2009, Volume: 22, Issue:8

    Topics: Age Factors; Aging; Biomarkers; Child; Child, Preschool; Creatine; Humans; Infant; Infant, Newborn;

2009
Regional age-related effects in the monkey brain measured with 1H magnetic resonance spectroscopy.
    Neurobiology of aging, 2011, Volume: 32, Issue:6

    Topics: Aging; Animals; Aspartic Acid; Brain; Brain Mapping; Choline; Creatine; Humans; Image Processing, Co

2011
Circulating endothelial progenitor cells and age-related white matter changes.
    Stroke, 2009, Volume: 40, Issue:10

    Topics: Age Distribution; Aged; Aging; Angiotensin-Converting Enzyme Inhibitors; Brain; C-Reactive Protein;

2009
Ontogeny regulates creatine metabolism in rat small and large intestine.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2009, Volume: 60, Issue:3

    Topics: Aging; Amidinotransferases; Animals; Animals, Newborn; Animals, Suckling; Blotting, Northern; Blotti

2009
Metabolite concentrations in supraventricular white matter from teenage to early old age: A short echo time 1H magnetic resonance spectroscopy (MRS) study.
    Acta radiologica (Stockholm, Sweden : 1987), 2010, Volume: 51, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Aging; Aspartic Acid; Biomarkers; Brain; Choline; Creatine; Fe

2010
Glycine-creatine metabolism in its relationship to aging.
    Journal of gerontology, 1947, Volume: 2, Issue:4

    Topics: Age Factors; Aging; Creatine; Glycine; Humans

1947
Reduction of hippocampal N-acetyl aspartate level in aged APP(Swe)/PS1(dE9) transgenic mice is associated with degeneration of CA3 pyramidal neurons.
    Journal of neuroscience research, 2010, Nov-01, Volume: 88, Issue:14

    Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Benzothiazoles; CA

2010
Maturation of limbic regions in Asperger syndrome: a preliminary study using proton magnetic resonance spectroscopy and structural magnetic resonance imaging.
    Psychiatry research, 2010, Nov-30, Volume: 184, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aging; Amygdala; Aspartic Acid; Asperger Syndrome; Brain Mapping; Ch

2010
Age-related differences in metabolites in the posterior cingulate cortex and hippocampus of normal ageing brain: a 1H-MRS study.
    European journal of radiology, 2012, Volume: 81, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Aging; Analysis of Variance; Aspartic Acid; Choline; Creatine;

2012
Postnatal trends in creatinemia and its covariates in extremely low birth weight (ELBW) neonates.
    Pediatric nephrology (Berlin, Germany), 2011, Volume: 26, Issue:10

    Topics: Adult; Aging; Anti-Inflammatory Agents, Non-Steroidal; Apgar Score; Birth Weight; Cohort Studies; Cr

2011
Longitudinal inter- and intra-individual human brain metabolic quantification over 3 years with proton MR spectroscopy at 3 T.
    Magnetic resonance in medicine, 2012, Volume: 67, Issue:1

    Topics: Aging; Algorithms; Aspartic Acid; Brain; Choline; Creatine; Humans; Inositol; Longitudinal Studies;

2012
Daydreaming about our metaphorical tool belt.
    AJNR. American journal of neuroradiology, 2012, Volume: 33, Issue:3

    Topics: Aging; Aspartic Acid; Brain; Brain Ischemia; Choline; Creatine; Female; Humans; Male

2012
The effect of age and cerebral ischemia on diffusion-weighted proton MR spectroscopy of the human brain.
    AJNR. American journal of neuroradiology, 2012, Volume: 33, Issue:3

    Topics: Adult; Aging; Aspartic Acid; Brain; Brain Ischemia; Choline; Creatine; Female; Humans; Male; Reprodu

2012
Longitudinal evaluation of intramyocellular lipids (IMCLs) in tibialis anterior muscle of ob/ob and ob/+ control mice using a cryogenic surface coil at 9.4 T.
    NMR in biomedicine, 2011, Volume: 24, Issue:10

    Topics: Aging; Animals; Body Weight; Cold Temperature; Creatine; Feasibility Studies; Insulin; Lipid Metabol

2011
Age-related changes in brain metabolites and cognitive function in APP/PS1 transgenic mice.
    Behavioural brain research, 2012, Nov-01, Volume: 235, Issue:1

    Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Biomarkers; Cholin

2012
Procedure for quantitative (1)H magnetic resonance spectroscopy and tissue characterization of human brain tissue based on the use of quantitative magnetic resonance imaging.
    Magnetic resonance in medicine, 2013, Volume: 70, Issue:4

    Topics: Adolescent; Adult; Aged; Aging; Creatine; Female; Humans; Inositol; Magnetic Resonance Imaging; Magn

2013
Renal cortical nitric oxide synthase activity during maturational growth in the rat.
    Pediatric nephrology (Berlin, Germany), 2002, Volume: 17, Issue:8

    Topics: Aging; Animals; Body Weight; Creatine; Cyclic GMP; Enzyme Inhibitors; Hemodynamics; Kidney Cortex; L

2002
Brain changes with aging: MR spectroscopy at supraventricular plane shows differences between women and men.
    Radiology, 2003, Volume: 226, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Aspartic Acid; Brain; Choline; Creatine; Female; Humans; Linear Mode

2003
Presence of (phospho)creatine in developing and adult skeletal muscle of mice without mitochondrial and cytosolic muscle creatine kinase isoforms.
    The Journal of physiology, 2003, May-01, Volume: 548, Issue:Pt 3

    Topics: Adenylate Kinase; Aging; Animals; Creatine; Creatine Kinase; Creatine Kinase, MM Form; Cytosol; Hind

2003
Memory training alters hippocampal neurochemistry in healthy elderly.
    Neuroreport, 2003, Jul-18, Volume: 14, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Aspartic Acid; Brain Chemistry; Brain Mapping; Cerebral Cortex; Chol

2003
Urinary excretion after the age of ninety; a study of neutral 17-ketosteroids, creatinine, and creatine.
    Journal of gerontology, 1956, Volume: 11, Issue:1

    Topics: 17-Ketosteroids; Aged; Aging; Body Fluids; Creatine; Creatinine; Humans; Hydrogen-Ion Concentration;

1956
[Creatinuria in aged rats & effects of d, 1-alpha-tocopherol acetate].
    Gerontologia, 1958, Volume: 2, Issue:3

    Topics: Aging; alpha-Tocopherol; Animals; Body Fluids; Creatine; Rats; Vitamin E

1958
[Experiments on influencing creatinuria of age by alpha-tocopherol acetate and selenium].
    Gerontologia, 1959, Volume: 3

    Topics: Aging; alpha-Tocopherol; Creatine; Creatinine; Humans; Selenium; Selenium Compounds; Urinalysis; Vit

1959
AGE AND SEX DIFFERENCES IN BODY DENSITY AND CREATININE EXCRETION OF HIGH SCHOOL CHILDREN.
    Annals of the New York Academy of Sciences, 1963, Sep-26, Volume: 110

    Topics: Adolescent; Aging; Body Composition; Child; Creatine; Creatinine; Humans; Sex; Sex Characteristics;

1963
BODY COMPOSITION STUDIES OF "OLDER" WOMEN, THIRTY TO SEVENTY YEARS OF AGE.
    Annals of the New York Academy of Sciences, 1963, Sep-26, Volume: 110

    Topics: Adipose Tissue; Aging; Anthropometry; Body Composition; Creatine; Creatinine; Female; Geriatrics; Hu

1963
TRENDS IN SELECTED INDICES OF BODY COMPOSITION IN MEN BETWEEN THE AGES 30 AND 80 YEARS.
    Annals of the New York Academy of Sciences, 1963, Sep-26, Volume: 110

    Topics: Aging; Anthropometry; Body Composition; Creatine; Creatinine; Geriatrics; Humans; Male; Metabolism;

1963
PLASMA CREATININE IN DIFFERENT SEX AND AGE GROUPS OF A HEALTHY ISOLATED ISLAND POPULATION.
    Acta medica Scandinavica, 1964, Volume: 175

    Topics: Aging; Biometry; Blood Chemical Analysis; Creatine; Creatinine; Finland; Islands; Kidney Function Te

1964
SERUM CREATINE AND CREATININE IN AGEING ALBINO RATS.
    Gerontologia, 1964, Volume: 49

    Topics: Aging; Blood; Creatine; Creatinine; Rats; Research

1964
SERUM AND MUSCLE CREATINE IN EXERCISED AGEING RATS.
    Gerontologia, 1964, Volume: 49

    Topics: Aging; Blood; Body Weight; Creatine; Creatinine; Exercise; Metabolism; Muscles; Physical Exertion; R

1964
AMINO ACID REQUIREMENTS OF CHILDREN: QUANTITATIVE AMINO ACID REQUIREMENTS OF GIRLS BASED ON NITROGEN BALANCE METHOD.
    The Journal of nutrition, 1965, Volume: 86, Issue:4

    Topics: 17-Ketosteroids; Aging; Amino Acids; Basal Metabolism; Body Height; Body Weight; Child; Creatine; Cr

1965
[INFLUENCE ON A ANABOLIC STEROID ON BEHAVIOR OF URINARY CREATINE AND CREATININE AT VARIOUS AGES. EXPERIMENTAL RESEARCH].
    Minerva pediatrica, 1965, Apr-28, Volume: 17

    Topics: Aging; Anabolic Agents; Animals; Body Fluids; Creatine; Creatinine; Guinea Pigs; Research; Steroids;

1965
[The metabolism of creatinic bodies in senescent animals].
    Giornale di gerontologia, 1960, Volume: 8

    Topics: Aging; Biochemical Phenomena; Coenzymes; Creatine; Creatinine

1960
Perinatal iron deficiency alters the neurochemical profile of the developing rat hippocampus.
    The Journal of nutrition, 2003, Volume: 133, Issue:10

    Topics: Aging; Animals; Aspartic Acid; Body Weight; Brain; Brain Chemistry; Creatine; Ethanolamines; Female;

2003
Quantitative MR analyses of the hippocampus: unspecific metabolic changes in aging.
    Journal of neurology, 2004, Volume: 251, Issue:11

    Topics: Adult; Age Factors; Aged; Aging; Analysis of Variance; Aspartic Acid; Attention; Brain Chemistry; Ch

2004
The age-related increase in N-methyl-2-pyridone-5-carboxamide (NAD catabolite) in human plasma.
    Molecular and cellular biochemistry, 2004, Volume: 267, Issue:1-2

    Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Aging; Animals; Blood Urea Nitrogen; C

2004
Age-related glutamate and glutamine concentration changes in normal human brain: 1H MR spectroscopy study at 4 T.
    Neurobiology of aging, 2005, Volume: 26, Issue:5

    Topics: Adult; Aged; Aging; Analysis of Variance; Aspartic Acid; Brain Chemistry; Creatine; Female; Glutamic

2005
Developmental decrease in rat small intestinal creatine uptake.
    Mechanisms of ageing and development, 2005, Volume: 126, Issue:4

    Topics: Aging; Animals; Biological Transport, Active; Creatine; Ileum; Jejunum; Rats; Rats, Wistar

2005
No effects of lifelong creatine supplementation on sarcopenia in senescence-accelerated mice (SAMP8).
    American journal of physiology. Endocrinology and metabolism, 2005, Volume: 289, Issue:2

    Topics: Aging; Animals; Creatine; Dietary Supplements; Energy Metabolism; Male; Mice; Mice, Inbred Strains;

2005
Age-related metabolic changes in the upper brainstem tegmentum by MR spectroscopy.
    Neurobiology of aging, 2005, Volume: 26, Issue:7

    Topics: Adult; Aged; Aging; Analysis of Variance; Aspartic Acid; Brain Mapping; Choline; Creatine; Female; H

2005
High resolution 1H NMR-based metabolomics indicates a neurotransmitter cycling deficit in cerebral tissue from a mouse model of Batten disease.
    The Journal of biological chemistry, 2005, Dec-30, Volume: 280, Issue:52

    Topics: Aging; Animals; Aspartic Acid; Brain; Cerebellum; Cerebral Cortex; Creatine; Disease Models, Animal;

2005
MRS of normal and impaired fetal brain development.
    European journal of radiology, 2006, Volume: 57, Issue:2

    Topics: Aging; Aspartic Acid; Brain; Choline; Creatine; Female; Fetal Development; Fetus; gamma-Aminobutyric

2006
Longitudinal changes during aging using proton magnetic resonance spectroscopy.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2006, Volume: 61, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Analysis of Variance; Aspartic Acid; Brain; Chi-Square Distribution;

2006
Methods for the diagnosis of creatine deficiency syndromes: a comparative study.
    Journal of neuroscience methods, 2006, Sep-30, Volume: 156, Issue:1-2

    Topics: Adolescent; Aging; Biomarkers; Child; Child, Preschool; Chromatography, High Pressure Liquid; Creati

2006
Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults.
    PloS one, 2007, Oct-03, Volume: 2, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Body Composition; Creatine; Exercise; Female; Humans; Isometric Cont

2007
Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults.
    PloS one, 2007, Oct-03, Volume: 2, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Body Composition; Creatine; Exercise; Female; Humans; Isometric Cont

2007
Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults.
    PloS one, 2007, Oct-03, Volume: 2, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Body Composition; Creatine; Exercise; Female; Humans; Isometric Cont

2007
Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults.
    PloS one, 2007, Oct-03, Volume: 2, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Body Composition; Creatine; Exercise; Female; Humans; Isometric Cont

2007
Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults.
    PloS one, 2007, Oct-03, Volume: 2, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Body Composition; Creatine; Exercise; Female; Humans; Isometric Cont

2007
Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults.
    PloS one, 2007, Oct-03, Volume: 2, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Body Composition; Creatine; Exercise; Female; Humans; Isometric Cont

2007
Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults.
    PloS one, 2007, Oct-03, Volume: 2, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Body Composition; Creatine; Exercise; Female; Humans; Isometric Cont

2007
Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults.
    PloS one, 2007, Oct-03, Volume: 2, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Body Composition; Creatine; Exercise; Female; Humans; Isometric Cont

2007
Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults.
    PloS one, 2007, Oct-03, Volume: 2, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Body Composition; Creatine; Exercise; Female; Humans; Isometric Cont

2007
Prevalence and predictors of cardiac hypertrophy and dysfunction in patients with Type 2 diabetes.
    Clinical science (London, England : 1979), 2008, Volume: 114, Issue:4

    Topics: Aging; Analysis of Variance; Antihypertensive Agents; Cardiomegaly; Creatine; Cross-Sectional Studie

2008
Decrease of NAA with aging outside the seizure focus in mesial temporal lobe epilepsy--a proton-MRS study at 3 Tesla.
    Brain research, 2007, Nov-07, Volume: 1179

    Topics: Adolescent; Adult; Aging; Aspartic Acid; Choline; Creatine; Drug Resistance; Epilepsy, Temporal Lobe

2007
Metabolic changes in the normal ageing brain: consistent findings from short and long echo time proton spectroscopy.
    European journal of radiology, 2008, Volume: 68, Issue:2

    Topics: Adolescent; Adult; Aged; Aging; Aspartic Acid; Brain; Choline; Creatine; Female; Humans; Imaging, Th

2008
Long and short echo time proton magnetic resonance spectroscopic imaging of the healthy aging brain.
    Journal of magnetic resonance imaging : JMRI, 2007, Volume: 26, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Artifacts; Aspartic Acid; Brain; Choline; Creatine; Dipeptides; Fema

2007
Thermal and storage stability of nutraceuticals in a milk beverage dietary supplement.
    Journal of food science, 2007, Volume: 72, Issue:3

    Topics: Aging; Animals; Beverages; Chondroitin Sulfates; Chromatography, High Pressure Liquid; Creatine; Die

2007
Cardiac structure and function during ageing in energetically compromised Guanidinoacetate N-methyltransferase (GAMT)-knockout mice - a one year longitudinal MRI study.
    Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2008, Feb-06, Volume: 10

    Topics: Aging; Animals; Creatine; Female; Guanidinoacetate N-Methyltransferase; Heart; Image Processing, Com

2008
Covariates of tramadol disposition in the first months of life.
    British journal of anaesthesia, 2008, Volume: 100, Issue:4

    Topics: Aging; Analgesics, Opioid; Creatine; Cytochrome P-450 CYP2D6; Genotype; Humans; Infant; Infant, Newb

2008
Long-term plasma levels and dose modulation of alacepril in patients with chronic renal failure.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:1

    Topics: Aging; Algorithms; Angiotensin-Converting Enzyme Inhibitors; Body Weight; Captopril; Creatine; Creat

2008
Hippocampal neurochemistry, neuromorphometry, and verbal memory in nondemented older adults.
    Neurology, 2008, Apr-29, Volume: 70, Issue:18

    Topics: Aged; Aged, 80 and over; Aging; Aspartic Acid; Creatine; Female; Hippocampus; Humans; Magnetic Reson

2008
Early and sustained alterations in cerebral metabolism after traumatic brain injury in immature rats.
    Journal of neurotrauma, 2008, Volume: 25, Issue:6

    Topics: Aging; Alanine; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Injuries; Cell Respiration; C

2008
The effect of age on the creatine in red cells.
    British journal of haematology, 1967, Volume: 13, Issue:2

    Topics: Aging; Anemia, Hemolytic, Autoimmune; Anemia, Hypochromic; Anemia, Macrocytic; Creatine; Erythrocyte

1967
Compatibility of normal renal function with aging.
    JAMA, 1967, Sep-04, Volume: 201, Issue:10

    Topics: Adult; Aged; Aging; Creatine; Female; Glomerular Filtration Rate; Humans; Kidney; Kidney Function Te

1967
Age-related changes in parathyroid hormone and parathyroid hormone action in normal humans.
    The Journal of clinical endocrinology and metabolism, 1984, Volume: 58, Issue:2

    Topics: Adult; Aged; Aging; Alkaline Phosphatase; Calcifediol; Calcium; Creatine; Cyclic AMP; Fasting; Femal

1984
The influence of intravenous furosemide on the renal excretion pattern of protein and protein degradation products.
    Acta pharmacologica et toxicologica, 1984, Volume: 54, Issue:5

    Topics: Aged; Aging; Albuminuria; beta 2-Microglobulin; Creatine; Furosemide; Humans; Hydrogen-Ion Concentra

1984
The effect of physical training in elderly subjects with special reference to energy-rich phosphagens and myoglobin in leg skeletal muscle.
    Clinical physiology (Oxford, England), 1982, Volume: 2, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aged; Aging; Blood Glucose; Creatine; Exercise Test;

1982
[Deficiency of amino acid precursors of chemical mediators and of creatine in the aged].
    Minerva medica, 1981, Sep-08, Volume: 72, Issue:32

    Topics: Acetylcholine; Aged; Aging; Amino Acids; Creatine; Depression; Histamine; Humans; Nicotinic Acids; S

1981
Effect of aging on energy-rich phosphagens in human skeletal muscles.
    Clinical science (London, England : 1979), 1980, Volume: 58, Issue:6

    Topics: Adenine Nucleotides; Aged; Aging; Creatine; Energy Metabolism; Female; Humans; Lactates; Male; Middl

1980
Age-dependent neurotoxicity of striatal lesions produced by aminooxyacetic acid: quantitative in vitro 1H NMR spectroscopic studies.
    Journal of neurochemistry, 1995, Volume: 65, Issue:3

    Topics: Aging; Alanine; Animals; Aspartic Acid; Corpus Striatum; Creatine; Energy Metabolism; gamma-Aminobut

1995
Age dependence of myosin heavy chain transitions induced by creatine depletion in rat skeletal muscle.
    Journal of applied physiology (Bethesda, Md. : 1985), 1995, Volume: 78, Issue:1

    Topics: Aging; Animals; Body Weight; Creatine; Female; Guanidines; Male; Muscle, Skeletal; Myofibrils; Myosi

1995
Comparison of the effects of salbutamol and clenbuterol on skeletal muscle mass and carcass composition in senescent rats.
    Metabolism: clinical and experimental, 1994, Volume: 43, Issue:9

    Topics: Adrenergic beta-Agonists; Aging; Albuterol; Animals; Body Composition; Body Weight; Clenbuterol; Cre

1994
Effect of clenbuterol on recovery of muscle mass and carcass protein content following dietary protein depletion in young and old rats.
    Journal of gerontology, 1994, Volume: 49, Issue:4

    Topics: Aging; Animals; Body Composition; Body Water; Body Weight; Clenbuterol; Creatine; Creatinine; Dietar

1994
Association between calcium regulatory hormones and other factors and bone mineral density in elderly Chinese men and women.
    Journal of gerontology, 1994, Volume: 49, Issue:4

    Topics: 25-Hydroxyvitamin D 2; Aged; Aging; Antihypertensive Agents; Body Mass Index; Bone and Bones; Bone D

1994
Axonal injury and membrane alterations in Alzheimer's disease suggested by in vivo proton magnetic resonance spectroscopic imaging.
    Annals of neurology, 1994, Volume: 36, Issue:1

    Topics: Aged; Aging; Alzheimer Disease; Aspartic Acid; Axons; Brain; Cerebral Cortex; Cerebral Ventricles; C

1994
Effects of age, sex, season and diet on serum ionized calcium, parathyroid hormone and vitamin D in a random population.
    Journal of internal medicine, 1993, Volume: 234, Issue:2

    Topics: Adult; Aged; Aging; Calcium; Creatine; Diet; Female; Humans; Male; Middle Aged; Parathyroid Hormone;

1993
The concentration of N-acetyl aspartate, creatine + phosphocreatine, and choline in different parts of the brain in adulthood and senium.
    Magnetic resonance imaging, 1993, Volume: 11, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aging; Aspartic Acid; Brain; Choline; Creatine; Humans; Magnetic Res

1993
Peritoneal equilibration test results are different in infants, children, and adults.
    Journal of the American Society of Nephrology : JASN, 1995, Volume: 6, Issue:4

    Topics: Adolescent; Adult; Aging; Biological Transport; Child; Child, Preschool; Creatine; Glucose; Humans;

1995
In vivo proton magnetic resonance spectroscopy of the normal aging human brain.
    Life sciences, 1996, Volume: 58, Issue:22

    Topics: Adult; Aged; Aging; Body Water; Brain; Choline; Creatine; Glutamic Acid; Glutamine; Humans; Inositol

1996
Parathyroid cell proliferation in the rat: effect of age and of phosphate administration and recovery.
    Endocrinology, 1996, Volume: 137, Issue:11

    Topics: Aging; Analysis of Variance; Animals; Apoptosis; Biomarkers; Calcitriol; Calcium; Cell Division; Cel

1996
Hippocampal age-related changes in schizophrenia: a proton magnetic resonance spectroscopy study.
    Schizophrenia research, 1996, Oct-18, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aging; Aspartic Acid; Choline; Creatine; Female; Functional Laterali

1996
Effect of aging on the rate of muscle protein turnover in rat.
    Revista espanola de fisiologia, 1996, Volume: 52, Issue:4

    Topics: Aging; Animals; Body Weight; Creatine; Creatinine; DNA; Liver; Longitudinal Studies; Male; Methylhis

1996
Hypertrophy of colonic smooth muscle: structural remodeling, chemical composition, and force output.
    The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 1

    Topics: Actins; Adenine Nucleotides; Aging; Animals; Collagen; Colon; Creatine; Creatinine; Elastin; Electri

1997
Metabolite changes with age measured by proton magnetic resonance spectroscopy in normal subjects.
    Psychiatry and clinical neurosciences, 1997, Volume: 51, Issue:4

    Topics: Adult; Aged; Aging; Aspartic Acid; Brain Mapping; Creatine; Energy Metabolism; Female; Frontal Lobe;

1997
1H-MRS differentiates white matter hyperintensities in subcortical arteriosclerotic encephalopathy from those in normal elderly.
    Stroke, 1997, Volume: 28, Issue:10

    Topics: Aged; Aging; Aspartic Acid; Brain; Choline; Creatine; Humans; Intracranial Arteriosclerosis; Magneti

1997
Altered development of prefrontal neurons in rhesus monkeys with neonatal mesial temporo-limbic lesions: a proton magnetic resonance spectroscopic imaging study.
    Cerebral cortex (New York, N.Y. : 1991), 1997, Volume: 7, Issue:8

    Topics: Aging; Amygdala; Animals; Animals, Newborn; Aspartic Acid; Biomarkers; Choline; Creatine; Entorhinal

1997
Age-related brain changes in rhesus monkeys: a magnetic resonance spectroscopic study.
    Neuroreport, 1998, Jun-22, Volume: 9, Issue:9

    Topics: Aging; Animals; Aspartic Acid; Brain; Brain Chemistry; Choline; Cognition; Creatine; Female; Inosito

1998
Calciuria, magnesiuria and creatininuria--relation to age.
    Physiological research, 1998, Volume: 47, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Calcium; Child; Child, Preschool; Creatine; Human

1998
Creatine supplementation and age influence muscle metabolism during exercise.
    Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 85, Issue:4

    Topics: Adenosine Triphosphate; Adult; Aging; Creatine; Energy Metabolism; Exercise; Female; Food, Fortified

1998
Age-related changes in body composition, hydroxyproline, and creatinine excretion in normal women.
    Calcified tissue international, 1999, Volume: 64, Issue:1

    Topics: Absorptiometry, Photon; Adult; Aged; Aged, 80 and over; Aging; Body Composition; Bone and Bones; Bon

1999
In vivo spectroscopic quantification of the N-acetyl moiety, creatine, and choline from large volumes of brain gray and white matter: effects of normal aging.
    Magnetic resonance in medicine, 1999, Volume: 41, Issue:2

    Topics: Adult; Aged; Aging; Aspartic Acid; Brain Chemistry; Choline; Creatine; Female; Humans; Magnetic Reso

1999
Effects of dietary taurine supplementation or deprivation in aged male Fischer 344 rats.
    Mechanisms of ageing and development, 1999, Feb-01, Volume: 107, Issue:1

    Topics: Aging; Animals; Blood Urea Nitrogen; Body Weight; Brain; Chromatography, High Pressure Liquid; Creat

1999
MR image segmentation and tissue metabolite contrast in 1H spectroscopic imaging of normal and aging brain.
    Magnetic resonance in medicine, 1999, Volume: 41, Issue:4

    Topics: Adult; Age Factors; Aged; Aging; Aspartic Acid; Atrophy; Brain; Brain Chemistry; Choline; Creatine;

1999
1H chemical shift imaging of the human brain at age 60-90 years reveals metabolic differences between women and men.
    Magnetic resonance in medicine, 1999, Volume: 42, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Aspartic Acid; Blood Glucose; Brain; Choline; Creatine; Energy Metab

1999
In vitro proton and phosphorus NMR spectroscopic analysis of murine (C57Bl/6J) brain development.
    NMR in biomedicine, 1999, Volume: 12, Issue:7

    Topics: Aging; Animals; Aspartic Acid; Brain; Brain Chemistry; Chloroform; Creatine; gamma-Aminobutyric Acid

1999
A (1)H magnetic resonance spectroscopy study of aging in parietal white matter: implications for trials in multiple sclerosis.
    Magnetic resonance imaging, 2000, Volume: 18, Issue:4

    Topics: Adolescent; Adult; Aged; Aging; Aspartic Acid; Brain Chemistry; Choline; Creatine; Female; Humans; I

2000
Protective effect of the energy precursor creatine against toxicity of glutamate and beta-amyloid in rat hippocampal neurons.
    Journal of neurochemistry, 2000, Volume: 74, Issue:5

    Topics: Aging; Amyloid beta-Peptides; Animals; Cells, Cultured; Creatine; Dendrites; Energy Metabolism; Glut

2000
Contribution of prolonged ischemia and donor age to chronic renal allograft dysfunction.
    Journal of the American Society of Nephrology : JASN, 2000, Volume: 11, Issue:7

    Topics: Aging; Animals; Antigens; Creatine; Cryopreservation; Graft Survival; Ischemia; Kidney; Kidney Trans

2000
Increase in vulnerability of middle-aged rat brain to lead by cerebral energy depletion.
    Brain research bulletin, 2000, Jul-15, Volume: 52, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aging; Animals; Astrocytes; Brain; Brain Chemistry; C

2000
Prenatal programming of adult hypertension in the rat.
    Kidney international, 2001, Volume: 59, Issue:1

    Topics: Aging; Aldosterone; Animals; Apoptosis; Blood Pressure; Creatine; Dietary Proteins; Female; Fetal Gr

2001
Regional differences and metabolic changes in normal aging of the human brain: proton MR spectroscopic imaging study.
    AJNR. American journal of neuroradiology, 2001, Volume: 22, Issue:1

    Topics: Adult; Aging; Aspartic Acid; Brain; Choline; Creatine; Female; Humans; Magnetic Resonance Spectrosco

2001
Region and tissue differences of metabolites in normally aged brain using multislice 1H magnetic resonance spectroscopic imaging.
    Magnetic resonance in medicine, 2001, Volume: 45, Issue:5

    Topics: Aged; Aged, 80 and over; Aging; Analysis of Variance; Aspartic Acid; Brain; Brain Diseases; Choline;

2001
(1)H-MR spectroscopy differentiates mild cognitive impairment from normal brain aging.
    Neuroreport, 2001, Aug-08, Volume: 12, Issue:11

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Aspartic Acid; Brain Chemistry; Choline; Cognitio

2001
Muscularity as a function of species, sex and age in small mammals.
    The Physiologist, 1984, Volume: 27, Issue:6 Suppl

    Topics: Aging; Animals; Body Composition; Creatine; Cricetinae; Female; Guinea Pigs; Male; Mice; Muscle Deve

1984
Quantitative evaluation of cerebral metabolites and cerebral blood flow in patients with carotid stenosis.
    Neurological research, 2001, Volume: 23, Issue:6

    Topics: Adult; Aged; Aging; Aspartic Acid; Basal Ganglia; Brain Ischemia; Carotid Stenosis; Cerebral Cortex;

2001
Creatine monohydrate supplemented in swine finishing diets and fresh pork quality: II. Commercial applications.
    Journal of animal science, 2001, Volume: 79, Issue:12

    Topics: Aging; Animal Feed; Animals; Creatine; Dietary Supplements; Food Handling; Food-Processing Industry;

2001
Developmental delay in children: assessment with proton MR spectroscopy.
    AJNR. American journal of neuroradiology, 2002, Volume: 23, Issue:5

    Topics: Aging; Aspartic Acid; Brain; Child; Child, Preschool; Choline; Creatine; Developmental Disabilities;

2002
[CPK and CT in striated muscles (proceedings)].
    Archives internationales de physiologie et de biochimie, 1979, Volume: 87, Issue:1

    Topics: Aging; Animals; Anura; Chickens; Creatine; Creatine Kinase; Humans; Mice; Muscle Contraction; Muscle

1979
[Time course of total creatine during growth and regeneration of striated muscle (proceedings)].
    Archives internationales de physiologie et de biochimie, 1979, Volume: 87, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Creatine; Muscle Development; Muscles; Rats; Regeneration

1979
Effect of muscle mass decrease on age-related BMR changes.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1977, Volume: 43, Issue:6

    Topics: Adult; Aged; Aging; Basal Metabolism; Creatine; Humans; Male; Middle Aged; Muscles; Organ Size; Oxyg

1977
Restitution of ATP and creatine phosphate after experimental depletion in young, adult, and old rats.
    Gerontology, 1978, Volume: 24, Issue:2

    Topics: Adenosine Triphosphate; Aging; Animals; Brain; Creatine; Male; Muscles; Myocardium; Phosphocreatine;

1978
The influence of age on renal function and renin and aldosterone responses to sodium-volume expansion and contraction in normotensive and mildly hypertensive humans.
    American journal of hypertension, 1992, Volume: 5, Issue:8

    Topics: Adolescent; Adult; Aging; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Creatine; Cross-Se

1992
Preservation of renal function by percutaneous renal angioplasty in high-risk elderly patients: short-term outcome.
    Nephron, 1992, Volume: 60, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Angioplasty, Balloon; Creatine; Embolism; Female; Humans; Hypertensi

1992
In vivo 1H and 31P NMR spectroscopy of the developing rat brain.
    Magnetic resonance in medicine, 1992, Volume: 23, Issue:1

    Topics: Adenosine Triphosphate; Aging; Animals; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Hy

1992
Age-dependent changes in cardiac muscle metabolism upon replacement of creatine by beta- guanidinopropionic acid.
    Biochemical Society transactions, 1991, Volume: 19, Issue:2

    Topics: Adenosine Triphosphate; Aging; Animals; Citrate (si)-Synthase; Creatine; Creatine Kinase; Energy Met

1991
Renal function predicts colchicine toxicity: guidelines for the prophylactic use of colchicine in gout.
    The Journal of rheumatology, 1991, Volume: 18, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Body Weight; Colchicine; Creatine; Dose-Response Relationship

1991
Age influence on mononuclear phagocyte system Fc-receptor function in poststreptococcal nephritis.
    Nephron, 1991, Volume: 57, Issue:1

    Topics: Adolescent; Adult; Aged; Aging; Child; Chromium Radioisotopes; Creatine; Enzyme-Linked Immunosorbent

1991
Brain development: 1H magnetic resonance spectroscopy of rat brain extracts compared with chromatographic methods.
    Neurochemical research, 1990, Volume: 15, Issue:10

    Topics: Aging; Amino Acids; Animals; Aspartic Acid; Brain; Brain Chemistry; Chromatography, High Pressure Li

1990
Casual urine concentrations of sodium, potassium, and creatine in population studies of blood pressure.
    Journal of human hypertension, 1990, Volume: 4, Issue:6

    Topics: Adult; Aging; Alcohol Drinking; Blood Pressure; Body Mass Index; Creatine; Humans; Hypertension; Mal

1990
Effect of age on circulating immunoreactive and bioactive parathyroid hormone levels in women.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1987, Volume: 2, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alkaline Phosphatase; Calcium; Creatine; Female; Humans; Midd

1987
Age-related rise in parathyroid hormone in man: the use of intact and midmolecule antisera to distinguish hormone secretion from retention.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1987, Volume: 2, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aging; Calcium; Creatine; Female; Humans; Hydroxycholecalciferols; I

1987
Energy metabolism in rat brain in vivo studied by 31P nuclear magnetic resonance: changes during postnatal development.
    Archives of biochemistry and biophysics, 1986, Volume: 248, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aging; Animals; Animals, Newborn; Brain; Creatine; En

1986
Fractionation of urinary biocolloids in children and adults by gel filtration.
    Investigative urology, 1966, Volume: 4, Issue:1

    Topics: Adult; Aging; Body Weight; Chemistry Techniques, Analytical; Child; Child, Preschool; Chromatography

1966
[The energy metabolism of skeletal muscle in relation to aging].
    Bollettino della Societa italiana di biologia sperimentale, 1973, Oct-30, Volume: 49, Issue:20

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Aging; Animals; Creatine; Energy

1973
Creatine (total creatine).
    Monographs on atherosclerosis, 1974, Volume: 4, Issue:0

    Topics: Age Factors; Aging; Aorta; Arteries; Arteriosclerosis; Creatine; Creatine Kinase; Humans; Iliac Arte

1974
The variation of urinary oxalate excretion with age.
    The Journal of laboratory and clinical medicine, 1969, Volume: 73, Issue:6

    Topics: Adolescent; Adult; Aged; Aging; Body Surface Area; Carbon Isotopes; Creatine; Female; Humans; Kidney

1969
[Aging of skeletal muscles. Restitution of creatine phosphate of sksletal muscles after work in rats of different ages].
    Gerontologia, 1970, Volume: 16, Issue:2

    Topics: Age Factors; Aging; Animals; Creatine; Female; Male; Muscles; Phosphocreatine; Physical Exertion; Ra

1970
Estimation of creatine in red cells.
    Journal of clinical pathology, 1968, Volume: 21, Issue:3

    Topics: Aging; Creatine; Erythrocytes; Erythropoiesis; Humans

1968
Decreased restitution of creatine phosphate in white and red skeletal muscles during aging.
    Experientia, 1968, Sep-15, Volume: 24, Issue:9

    Topics: Aging; Animals; Creatine; Female; Male; Muscles; Phosphocreatine; Rats

1968