creatine has been researched along with Affective Psychosis, Bipolar in 91 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eight lithium-treated patients with DSM-IV bipolar disorder, rapid cycling type were randomly assigned to 50 mg/kg/day of choline bitartrate or placebo for 12 weeks." | 9.10 | Oral choline decreases brain purine levels in lithium-treated subjects with rapid-cycling bipolar disorder: a double-blind trial using proton and lithium magnetic resonance spectroscopy. ( Ahn, KH; Demopulos, CM; Hirashima, F; Lyoo, IK; Renshaw, PF, 2003) |
| "This project was designed to compare differences in brain proton spectra between children and adolescents with bipolar disorder (BPD) and gender and age-matched normal controls, and to measure changes in myo-inositol levels following lithium therapy, utilizing in vivo proton magnetic resonance spectroscopy (1H MRS)." | 9.09 | Decreased anterior cingulate myo-inositol/creatine spectroscopy resonance with lithium treatment in children with bipolar disorder. ( Belin, T; Davanzo, P; McCracken, J; Oshiro, T; Strober, M; Thomas, MA; Yue, K, 2001) |
| " However, there were no associations between NAA/Cr, Glu/Cr, or Gln/Cr and either depression severity or lamotrigine treatment." | 7.91 | Lamotrigine Therapy and Biomarkers of Cerebral Energy Metabolism in Older Age Bipolar Depression. ( Forester, BP; Harper, DG; Jensen, E; Mellen, EJ; Ravichandran, C; Silveri, M, 2019) |
| "The purpose of this study was to investigate the anterior cingulate cortex (ACC) glutamate/glutamine (Glx) to creatine ratio (Glx/Cr) in two groups of children with Bipolar Disorder (BPD): those exhibiting manic symptoms requiring treatment and those being stably treated with the atypical antipsychotic risperidone." | 7.74 | Mania, glutamate/glutamine and risperidone in pediatric bipolar disorder: a proton magnetic resonance spectroscopy study of the anterior cingulate cortex. ( Aleardi, M; Biederman, J; Dougherty, M; Hammerness, P; Harpold, T; Lyoo, IK; Mick, E; Moore, CM; Randall, E; Renshaw, PF; Wardrop, M; Wozniak, J, 2007) |
| "Eight lithium-treated patients with DSM-IV bipolar disorder, rapid cycling type were randomly assigned to 50 mg/kg/day of choline bitartrate or placebo for 12 weeks." | 5.10 | Oral choline decreases brain purine levels in lithium-treated subjects with rapid-cycling bipolar disorder: a double-blind trial using proton and lithium magnetic resonance spectroscopy. ( Ahn, KH; Demopulos, CM; Hirashima, F; Lyoo, IK; Renshaw, PF, 2003) |
| "This project was designed to compare differences in brain proton spectra between children and adolescents with bipolar disorder (BPD) and gender and age-matched normal controls, and to measure changes in myo-inositol levels following lithium therapy, utilizing in vivo proton magnetic resonance spectroscopy (1H MRS)." | 5.09 | Decreased anterior cingulate myo-inositol/creatine spectroscopy resonance with lithium treatment in children with bipolar disorder. ( Belin, T; Davanzo, P; McCracken, J; Oshiro, T; Strober, M; Thomas, MA; Yue, K, 2001) |
| "Response to lithium maintenance varies widely across patients with bipolar disorder (BD)." | 4.31 | Elevated choline in dorsolateral prefrontal cortex of lithium responders with bipolar I disorder. ( Deep, R; Khandelwal, SK; Kumaran, SS; Mahal, P, 2023) |
| " However, there were no associations between NAA/Cr, Glu/Cr, or Gln/Cr and either depression severity or lamotrigine treatment." | 3.91 | Lamotrigine Therapy and Biomarkers of Cerebral Energy Metabolism in Older Age Bipolar Depression. ( Forester, BP; Harper, DG; Jensen, E; Mellen, EJ; Ravichandran, C; Silveri, M, 2019) |
| "We wished to determine whether decreases in N-acetyl aspartate (NAA) and increases in myoinositol (mI) concentrations as a ratio of creatine (Cr) occurred in the dorsolateral prefrontal cortex (DLPFC) of pediatric offspring of parents with bipolar disorder (BD) and a healthy comparison group (HC) over a 5-year period using proton magnetic resonance spectroscopy ((1)H-MRS)." | 3.79 | Prospective neurochemical characterization of child offspring of parents with bipolar disorder. ( Adleman, NE; Bararpour, L; Chang, KD; Howe, M; Jo, B; Kelley, RG; Singh, MK; Spielman, D, 2013) |
| "The purpose of this study was to investigate the anterior cingulate cortex (ACC) glutamate/glutamine (Glx) to creatine ratio (Glx/Cr) in two groups of children with Bipolar Disorder (BPD): those exhibiting manic symptoms requiring treatment and those being stably treated with the atypical antipsychotic risperidone." | 3.74 | Mania, glutamate/glutamine and risperidone in pediatric bipolar disorder: a proton magnetic resonance spectroscopy study of the anterior cingulate cortex. ( Aleardi, M; Biederman, J; Dougherty, M; Hammerness, P; Harpold, T; Lyoo, IK; Mick, E; Moore, CM; Randall, E; Renshaw, PF; Wardrop, M; Wozniak, J, 2007) |
| "Compared to controls, schizophrenia and bipolar patients presented decreased NAA to creatine ratios, while only the schizophrenia group showed an increase in CSF in the dorsolateral prefrontal region." | 3.74 | Dorsolateral prefrontal N-acetyl-aspartate concentration in male patients with chronic schizophrenia and with chronic bipolar disorder. ( Benito, C; Desco, M; Leal, I; Molina, V; Palomo, T; Rebolledo, R; Reig, S; Sánchez, J; Sanz, J; Sarramea, F, 2007) |
| "The authors examined the levels of NAA, creatine plus phosphocreatine, and choline-containing molecules in the left dorsolateral prefrontal cortex of 14 bipolar disorder patients (mean age=15." | 3.73 | Reduced NAA levels in the dorsolateral prefrontal cortex of young bipolar patients. ( Axelson, D; Birmaher, B; Brambilla, P; Keshavan, MS; Nicoletti, MA; Ramos, RT; Ryan, N; Sassi, RB; Soares, JC; Stanley, JA, 2005) |
| "The authors' goal was to investigate phosphatidylinositol and glutamatergic metabolism in the anterior cingulate cortex of children and adolescents with attention deficit hyperactivity disorder (ADHD) alone, children with ADHD plus bipolar disorder, and children with no axis I diagnosis." | 3.73 | Differences in brain chemistry in children and adolescents with attention deficit hyperactivity disorder with and without comorbid bipolar disorder: a proton magnetic resonance spectroscopy study. ( Aleardi, M; Biederman, J; Dougherty, M; Hammerness, P; Harpold, T; Mick, E; Moore, CM; Randall, E; Renshaw, PF; Wardrop, M; Wozniak, J, 2006) |
| "Based on earlier structural and functional neuroimaging studies, we specifically wanted to assess N-acetylaspartate (NAA), choline-containing compounds (CHO), and creatine+phosphocreatine (CRE) levels in brain hippocampus previously demonstrated to be involved in the pathophysiology of bipolar disorder which have not been evaluated in first-episode patients." | 3.73 | Hippocampal 1H MRS in first-episode bipolar I patients. ( Atmaca, M; Ogur, E; Ozdemir, H; Poyraz, AK; Tezcan, E; Yildirim, H, 2006) |
| "The patients with bipolar disorder showed significantly higher anterior cingulate myo-inositol/creatine-phosphocreatine and myo-inositol (mmol/liter) levels than the patients with intermittent explosive disorder and the normal comparison subjects." | 3.72 | Proton magnetic resonance spectroscopy of bipolar disorder versus intermittent explosive disorder in children and adolescents. ( Barnett, S; Belin, T; Davanzo, P; McCracken, J; Mintz, J; Santoro, E; Thomas, MA; Venkatraman, TN; Yue, K, 2003) |
| "Eighteen (N=18) patients with bipolar depression according to DSM-IV criteria who were enrollled in a 6-week, randomized, double-blind, placebo-controlled trial of creatine monohydrate 6g daily as adjunctive therapy were submitted to neuropsychological assessments (Wisconsin Card Sorting Test, Digit Span subtest of the Wechsler Adult Intelligence Scale-Third Edition, Stroop Color-Word Test, Rey-Osterrieth complex figure test, FAS Verbal Fluency Test) at baseline and week 6." | 2.84 | Cognitive effects of creatine monohydrate adjunctive therapy in patients with bipolar depression: Results from a randomized, double-blind, placebo-controlled trial. ( Dias, RDS; Fernandes, FBF; Lafer, B; Silva, M; Toniolo, RA, 2017) |
| "Creatine plays a pivotal role in brain energy homeostasis, and altered cerebral energy metabolism may be involved in the pathophysiology of depression." | 2.73 | Creatine monohydrate in resistant depression: a preliminary study. ( Green, T; Karni, N; Levine, J; Osher, Y; Roitman, S, 2007) |
| " However, the study suggests that chronic administration of sodium valproate to patients does not lead to similar changes in NAA concentrations." | 2.71 | Chronic treatment with lithium, but not sodium valproate, increases cortical N-acetyl-aspartate concentrations in euthymic bipolar patients. ( Asghar, SJ; Hanstock, CC; O'Donnell, T; Silverstone, PH; Ulrich, M; Wu, RH, 2003) |
| "Alcoholism is highly prevalent among bipolar disorder (BD) patients, and its presence is associated with a worse outcome and refractoriness to treatment of the mood disorder." | 1.36 | Bipolar disorder comorbid with alcoholism: a 1H magnetic resonance spectroscopy study. ( Chen, HH; Hatch, JP; Lafer, B; Monkul, ES; Nery, FG; Nicoletti, MA; Soares, JC; Stanley, JA, 2010) |
| "Fourteen patients with chronic paranoid schizophrenia, 17 euthymic type I bipolar patients with no previous history of psychotic symptoms and 15 healthy controls were included, most of them were female." | 1.35 | Biochemical changes in the cingulum in patients with schizophrenia and chronic bipolar disorder. ( Albert, C; Cabaleiro, F; de Luxan, A; Galán, R; Leal, I; Luque, R; Molina, V; Osuna, MI; Prieto, D; Ruiz, M; Sarramea Crespo, F; Sau, P, 2008) |
| "These data suggest that non-melancholic bipolar depression is characterized by increased glutamate coupled with increased energy expenditure." | 1.34 | Increased anterior cingulate/medial prefrontal cortical glutamate and creatine in bipolar depression. ( Banakar, S; Chirichigno, JW; Davanzo, P; Elman, S; Fischer, J; Frye, MA; Mintz, J; O'Neill, J; Thomas, MA; Tsuang, J; Ventura, J; Walot, I; Watzl, J, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (6.59) | 18.7374 |
| 1990's | 4 (4.40) | 18.2507 |
| 2000's | 44 (48.35) | 29.6817 |
| 2010's | 32 (35.16) | 24.3611 |
| 2020's | 5 (5.49) | 2.80 |
| Authors | Studies |
|---|---|
| Magnotta, VA | 1 |
| Xu, J | 2 |
| Fiedorowicz, JG | 1 |
| Williams, A | 1 |
| Shaffer, J | 1 |
| Christensen, G | 1 |
| Long, JD | 1 |
| Taylor, E | 1 |
| Sathyaputri, L | 1 |
| Richards, JG | 1 |
| Harmata, G | 1 |
| Wemmie, J | 1 |
| Mahal, P | 3 |
| Deep, R | 3 |
| Kumaran, SS | 3 |
| Khandelwal, SK | 3 |
| Lai, S | 4 |
| Zhong, S | 5 |
| Shan, Y | 1 |
| Wang, Y | 5 |
| Chen, G | 2 |
| Luo, X | 1 |
| Chen, F | 1 |
| Zhang, Y | 3 |
| Shen, S | 1 |
| Huang, H | 1 |
| Ning, Y | 1 |
| Jia, Y | 5 |
| Kious, BM | 1 |
| Kondo, DG | 2 |
| Renshaw, PF | 8 |
| Bio, DS | 1 |
| Moreno, RA | 1 |
| Garcia-Otaduy, MC | 1 |
| Nery, F | 1 |
| Lafer, B | 6 |
| Soeiro-de-Souza, MG | 2 |
| Chen, J | 1 |
| Zou, S | 1 |
| Qu, Y | 1 |
| Zhang, C | 1 |
| Tang, X | 1 |
| Ren, Y | 1 |
| Scotti-Muzzi, E | 1 |
| Fernandes, F | 1 |
| De Sousa, RT | 1 |
| Leite, CC | 1 |
| Otaduy, MC | 1 |
| Machado-Vieira, R | 1 |
| Bond, DJ | 1 |
| Silveira, LE | 1 |
| MacMillan, EL | 1 |
| Torres, IJ | 1 |
| Lang, DJ | 1 |
| Su, W | 1 |
| Honer, WG | 1 |
| Lam, RW | 1 |
| Yatham, LN | 2 |
| Liao, X | 3 |
| Huang, J | 1 |
| Zhang, S | 1 |
| Sun, Y | 1 |
| Zhao, H | 1 |
| Toniolo, RA | 2 |
| Silva, M | 2 |
| Fernandes, FBF | 2 |
| Amaral, JAMS | 1 |
| Dias, RDS | 2 |
| Atagün, Mİ | 2 |
| Şıkoğlu, EM | 2 |
| Can, SS | 2 |
| Uğurlu, GK | 1 |
| Kaymak, SU | 1 |
| Çayköylü, A | 2 |
| Algın, O | 2 |
| Phillips, ML | 2 |
| Moore, CM | 4 |
| Öngür, D | 5 |
| Li, C | 1 |
| Wang, A | 1 |
| Wang, C | 1 |
| Ramamurthy, J | 1 |
| Zhang, E | 1 |
| Guadagno, E | 1 |
| Trakadis, Y | 1 |
| Liu, T | 2 |
| Jelen, LA | 1 |
| King, S | 1 |
| Horne, CM | 1 |
| Lythgoe, DJ | 1 |
| Young, AH | 1 |
| Stone, JM | 1 |
| Nery, FG | 4 |
| Weber, WA | 1 |
| Blom, TJ | 1 |
| Welge, J | 2 |
| Patino, LR | 1 |
| Strawn, JR | 1 |
| Chu, WJ | 3 |
| Adler, CM | 3 |
| Komoroski, RA | 1 |
| Strakowski, SM | 3 |
| DelBello, MP | 3 |
| Mellen, EJ | 1 |
| Harper, DG | 1 |
| Ravichandran, C | 1 |
| Jensen, E | 1 |
| Silveri, M | 1 |
| Forester, BP | 1 |
| Lewandowski, KE | 1 |
| Du, F | 1 |
| Fan, X | 1 |
| Chen, X | 1 |
| Huynh, P | 1 |
| Jarvis, KB | 1 |
| Norris, MM | 1 |
| Kim, MJ | 1 |
| Weber, W | 1 |
| Lee, JH | 1 |
| Dydak, U | 1 |
| Harezlak, J | 1 |
| Nixon, J | 1 |
| Dzemidzic, M | 1 |
| Gunn, AD | 1 |
| Karne, HS | 1 |
| Anand, A | 1 |
| Gigante, AD | 1 |
| Singh, MK | 1 |
| Jo, B | 1 |
| Adleman, NE | 1 |
| Howe, M | 2 |
| Bararpour, L | 1 |
| Kelley, RG | 1 |
| Spielman, D | 2 |
| Chang, KD | 2 |
| Hajek, T | 1 |
| Calkin, C | 1 |
| Blagdon, R | 1 |
| Slaney, C | 1 |
| Alda, M | 1 |
| Shi, XF | 1 |
| Forrest, LN | 1 |
| Kuykendall, MD | 1 |
| Prescot, AP | 3 |
| Sung, YH | 1 |
| Huber, RS | 1 |
| Hellem, TL | 1 |
| Jeong, EK | 1 |
| Zhao, G | 1 |
| Xiang, Q | 1 |
| Ling, X | 1 |
| Liu, S | 1 |
| Huang, L | 1 |
| Karakaş-Uğurlu, G | 1 |
| Ulusoy-Kaymak, S | 1 |
| Chitty, KM | 1 |
| Lagopoulos, J | 1 |
| Hickie, IB | 1 |
| Hermens, DF | 1 |
| Cao, B | 1 |
| Stanley, JA | 7 |
| Selvaraj, S | 1 |
| Mwangi, B | 1 |
| Passos, IC | 1 |
| Zunta-Soares, GB | 1 |
| Soares, JC | 7 |
| Lotfi, M | 1 |
| Shafiee, S | 1 |
| Ghanizadeh, A | 1 |
| Sigaroudi, MO | 1 |
| Razeghian, L | 1 |
| Tan, HZ | 1 |
| Li, H | 2 |
| Liu, CF | 1 |
| Guan, JT | 1 |
| Guo, XB | 1 |
| Wen, CH | 1 |
| Ou, SM | 1 |
| Zhang, YN | 1 |
| Zhang, J | 3 |
| Xu, CT | 1 |
| Shen, ZW | 1 |
| Wu, RH | 2 |
| Wang, XQ | 1 |
| Xu, H | 1 |
| Guan, J | 1 |
| Xu, C | 1 |
| Shen, Z | 1 |
| Xiao, B | 1 |
| Liang, C | 1 |
| Chen, K | 1 |
| Wu, R | 1 |
| Wang, B | 1 |
| Patel, NC | 1 |
| Cecil, KM | 1 |
| Dickstein, DP | 2 |
| Towbin, KE | 2 |
| Van Der Veen, JW | 2 |
| Rich, BA | 1 |
| Brotman, MA | 1 |
| Knopf, L | 2 |
| Onelio, L | 1 |
| Pine, DS | 2 |
| Leibenluft, E | 2 |
| Michael, N | 2 |
| Erfurth, A | 2 |
| Pfleiderer, B | 2 |
| Jensen, JE | 2 |
| Cohen, BM | 2 |
| Benedetti, F | 1 |
| Calabrese, G | 1 |
| Bernasconi, A | 1 |
| Cadioli, M | 1 |
| Colombo, C | 1 |
| Dallaspezia, S | 1 |
| Falini, A | 1 |
| Radaelli, D | 1 |
| Scotti, G | 1 |
| Smeraldi, E | 1 |
| Chen, HH | 3 |
| Hatch, JP | 4 |
| Nicoletti, MA | 5 |
| Monkul, ES | 2 |
| Rouse, ED | 1 |
| Olson, DP | 1 |
| Scherk, H | 4 |
| Backens, M | 4 |
| Schneider-Axmann, T | 4 |
| Usher, J | 3 |
| Kemmer, C | 3 |
| Reith, W | 4 |
| Falkai, P | 4 |
| Gruber, O | 4 |
| Sumegi, A | 1 |
| Halasz, S | 1 |
| Kliment, E | 1 |
| Hasan, A | 1 |
| Wobrock, T | 1 |
| Ekawardhani, S | 1 |
| Schmitt, A | 1 |
| Meyer, J | 2 |
| Shahana, N | 1 |
| Delbello, M | 1 |
| Jarvis, K | 1 |
| Fleck, D | 1 |
| Strakowski, S | 1 |
| Adler, C | 1 |
| Silverstone, PH | 2 |
| O'Donnell, T | 2 |
| Ulrich, M | 2 |
| Asghar, SJ | 2 |
| Hanstock, CC | 2 |
| Ohrmann, P | 1 |
| Gössling, M | 1 |
| Arolt, V | 1 |
| Heindel, W | 1 |
| Deicken, RF | 2 |
| Pegues, MP | 1 |
| Anzalone, S | 1 |
| Feiwell, R | 2 |
| Soher, B | 1 |
| Chang, K | 1 |
| Adleman, N | 1 |
| Dienes, K | 1 |
| Barnea-Goraly, N | 1 |
| Reiss, A | 2 |
| Ketter, T | 1 |
| Lyoo, IK | 3 |
| Demopulos, CM | 1 |
| Hirashima, F | 1 |
| Ahn, KH | 1 |
| Davanzo, P | 4 |
| Yue, K | 3 |
| Thomas, MA | 4 |
| Belin, T | 2 |
| Mintz, J | 3 |
| Venkatraman, TN | 1 |
| Santoro, E | 1 |
| Barnett, S | 1 |
| McCracken, J | 2 |
| SOULAIRAC, A | 1 |
| GEIER, S | 1 |
| Wood, SJ | 1 |
| Berger, G | 1 |
| Velakoulis, D | 1 |
| Phillips, LJ | 1 |
| McGorry, PD | 1 |
| Yung, AR | 1 |
| Desmond, P | 1 |
| Pantelis, C | 1 |
| Dager, SR | 1 |
| Friedman, SD | 1 |
| Parow, A | 1 |
| Demopulos, C | 1 |
| Stoll, AL | 1 |
| Dunner, DL | 1 |
| Blasi, G | 1 |
| Bertolino, A | 1 |
| Brudaglio, F | 1 |
| Sciota, D | 1 |
| Altamura, M | 1 |
| Antonucci, N | 1 |
| Scarabino, T | 1 |
| Weinberger, DR | 1 |
| Nardini, M | 1 |
| Brambilla, P | 2 |
| Sassi, RB | 2 |
| Mallinger, AG | 1 |
| Frank, E | 1 |
| Kupfer, D | 1 |
| Keshavan, MS | 2 |
| Axelson, D | 1 |
| Ramos, RT | 1 |
| Ryan, N | 1 |
| Birmaher, B | 1 |
| Gallelli, KA | 1 |
| Wagner, CM | 1 |
| Karchemskiy, A | 1 |
| Biederman, J | 2 |
| Wozniak, J | 2 |
| Mick, E | 2 |
| Aleardi, M | 2 |
| Wardrop, M | 2 |
| Dougherty, M | 2 |
| Harpold, T | 2 |
| Hammerness, P | 2 |
| Randall, E | 2 |
| Yildiz-Yesiloglu, A | 1 |
| Ankerst, DP | 1 |
| Atmaca, M | 1 |
| Yildirim, H | 1 |
| Ozdemir, H | 1 |
| Poyraz, AK | 1 |
| Tezcan, E | 1 |
| Ogur, E | 1 |
| Amaral, JA | 1 |
| Tamada, RS | 1 |
| Issler, CK | 1 |
| Caetano, SC | 3 |
| Cerri, GG | 1 |
| de Castro, CC | 1 |
| Viguera, AC | 1 |
| Newport, DJ | 1 |
| Ritchie, J | 1 |
| Stowe, Z | 1 |
| Whitfield, T | 1 |
| Mogielnicki, J | 1 |
| Baldessarini, RJ | 1 |
| Zurick, A | 1 |
| Cohen, LS | 1 |
| Frye, MA | 2 |
| Binesh, N | 1 |
| Ventura, J | 2 |
| O'Neill, J | 2 |
| Guze, B | 1 |
| Curran, JG | 1 |
| Watzl, J | 1 |
| Banakar, S | 1 |
| Fischer, J | 1 |
| Chirichigno, JW | 1 |
| Elman, S | 1 |
| Tsuang, J | 1 |
| Walot, I | 1 |
| Raedler, TJ | 1 |
| Wiedemann, K | 1 |
| Frey, BN | 2 |
| Ortiz, O | 1 |
| Kapczinski, F | 1 |
| Olvera, RL | 1 |
| Fonseca, M | 1 |
| Nicoletti, M | 1 |
| Hunter, K | 1 |
| Pliszka, SR | 1 |
| Walss-Bass, C | 1 |
| Matsuo, K | 1 |
| Bowden, CL | 1 |
| Escamilla, MA | 1 |
| Molina, V | 2 |
| Sánchez, J | 1 |
| Sanz, J | 1 |
| Reig, S | 1 |
| Benito, C | 1 |
| Leal, I | 2 |
| Sarramea, F | 1 |
| Rebolledo, R | 1 |
| Palomo, T | 1 |
| Desco, M | 1 |
| Kraft, S | 1 |
| Roitman, S | 1 |
| Green, T | 1 |
| Osher, Y | 1 |
| Karni, N | 1 |
| Levine, J | 2 |
| Port, JD | 1 |
| Unal, SS | 1 |
| Mrazek, DA | 1 |
| Marcus, SM | 1 |
| Lan, MJ | 1 |
| McLoughlin, GA | 1 |
| Griffin, JL | 1 |
| Tsang, TM | 1 |
| Huang, JT | 1 |
| Yuan, P | 1 |
| Manji, H | 1 |
| Holmes, E | 1 |
| Bahn, S | 1 |
| Colla, M | 1 |
| Schubert, F | 1 |
| Bubner, M | 1 |
| Heidenreich, JO | 1 |
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| Heuser, I | 1 |
| Kronenberg, G | 1 |
| Sarramea Crespo, F | 1 |
| Luque, R | 1 |
| Prieto, D | 1 |
| Sau, P | 1 |
| Albert, C | 1 |
| de Luxan, A | 1 |
| Osuna, MI | 1 |
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| Venkatasubramanian, PN | 1 |
| Bárány, M | 1 |
| Davis, JM | 1 |
| De Martinis, C | 1 |
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| Chattaway, FW | 1 |
| Hullin, RP | 1 |
| Odds, FC | 1 |
| Meltzer, HY | 1 |
| Moline, R | 1 |
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| Lobban, MC | 1 |
| Sloane, RB | 1 |
| Hughes, W | 1 |
| Haust, HL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Double-Blind, Randomized, Placebo-Controlled Clinical Trial to Evaluate the Efficacy of Creatine Monohydrate as Adjunctive Therapy for Bipolar Depression[NCT01655030] | 44 participants (Actual) | Interventional | 2012-07-31 | Completed | |||
| 1/2-MC4R Genotype and Pediatric Antipsychotic Drug- Induced Weight Gain[NCT01844700] | Phase 4 | 14 participants (Actual) | Interventional | 2013-07-31 | Terminated (stopped due to very slow recruitment, no sufficient results) | ||
| Imaging Framework for Testing GABAergic/Glutamatergic Drugs in Bipolar Alcoholics[NCT03220776] | Phase 2 | 54 participants (Actual) | Interventional | 2017-08-07 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01844700)
Timeframe: baseline to week 12
| Intervention | percentage of weight change (Mean) |
|---|---|
| Ziprasidone | 11.58 |
| Aripiprazole, Quetiapine, Risperidone | 5.66 |
(NCT01844700)
Timeframe: baseline to week 12
| Intervention | BMI percentile (Mean) | |
|---|---|---|
| baseline | week 12 (n=1, n=2) | |
| Aripiprazole, Quetiapine, Risperidone | 37.67 | 62.5 |
| Ziprasidone | 32 | 59 |
(NCT01844700)
Timeframe: baseline to week 12
| Intervention | BMI z-score (Mean) | |
|---|---|---|
| baseline | week 12 (n=1, n=2) | |
| Aripiprazole, Quetiapine, Risperidone | -0.37 | 0.38 |
| Ziprasidone | -0.51 | 0.22 |
(NCT01844700)
Timeframe: baseline to week 12
| Intervention | lbs (Mean) | |
|---|---|---|
| baseline | week 12 (n=1,2) | |
| Aripiprazole, Quetiapine, Risperidone | 118.5 | 141 |
| Ziprasidone | 120.5 | 151 |
Concentrations of GABA+, referenced to unsuppressed water and corrected for within-voxel CSF proportion, in dorsal anterior cingulate cortex measured via Proton Magnetic Resonance Spectroscopy (i.e., MEGA-PRESS). (NCT03220776)
Timeframe: Day 5 of each experimental condition
| Intervention | mmol/kg (Mean) |
|---|---|
| N-Acetylcysteine | 3.90 |
| Gabapentin | 3.93 |
| Placebo Oral Tablet | 3.73 |
Concentrations of Glx (i.e., glutamate + glutamine), referenced to unsuppressed water and corrected for within-voxel CSF proportion, in dorsal anterior cingulate cortex measured via Proton Magnetic Resonance Spectroscopy. (NCT03220776)
Timeframe: Day 5 of each experimental condition
| Intervention | mmol/kg (Mean) |
|---|---|
| N-Acetylcysteine | 21.59 |
| Gabapentin | 21.69 |
| Placebo Oral Tablet | 22.25 |
5 reviews available for creatine and Affective Psychosis, Bipolar
| Article | Year |
|---|---|
Creatine for the Treatment of Depression.
Topics: Animals; Bipolar Disorder; Brain; Clinical Studies as Topic; Creatine; Depressive Disorder, Major; E | 2019 |
Metabolomics in patients with psychosis: A systematic review.
Topics: 3-Hydroxybutyric Acid; Aspartic Acid; Biomarkers; Bipolar Disorder; Creatine; Female; Glutamic Acid; | 2018 |
Lithium and valproate protect against dextro-amphetamine induced brain choline concentration changes in bipolar disorder patients.
Topics: Antipsychotic Agents; Bipolar Disorder; Brain; Choline; Creatine; Dextroamphetamine; Female; Humans; | 2004 |
Neurochemical alterations of the brain in bipolar disorder and their implications for pathophysiology: a systematic review of the in vivo proton magnetic resonance spectroscopy findings.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain Chemistry; Child; Choline; Creatine; Glutamic Acid; Gl | 2006 |
Lithium-induced nephropathies.
Topics: Adult; Antimanic Agents; Bipolar Disorder; Creatine; Diabetes Insipidus, Nephrogenic; Dose-Response | 2007 |
11 trials available for creatine and Affective Psychosis, Bipolar
| Article | Year |
|---|---|
A randomized, double-blind, placebo-controlled, proof-of-concept trial of creatine monohydrate as adjunctive treatment for bipolar depression.
Topics: Adult; Antidepressive Agents; Antioxidants; Bipolar Disorder; Creatine; Dietary Supplements; Double- | 2018 |
A Magnetic Resonance Spectroscopy Study of Lovastatin for Treating Bipolar Mood Disorder: A 4-Week Randomized Double-Blind, Placebo- Controlled Clinical Trial.
Topics: Adolescent; Adult; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Brain; Choline; Creatine; Doub | 2017 |
Cognitive effects of creatine monohydrate adjunctive therapy in patients with bipolar depression: Results from a randomized, double-blind, placebo-controlled trial.
Topics: Adult; Antidepressive Agents; Bipolar Disorder; Cognition; Cognitive Dysfunction; Combined Modality | 2017 |
Randomized double-blind placebo-controlled trial of lithium in youths with severe mood dysregulation.
Topics: Adolescent; Antimanic Agents; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Bipolar | 2009 |
Spectroscopic correlates of antidepressant response to sleep deprivation and light therapy: a 3.0 Tesla study of bipolar depression.
Topics: Adult; Antidepressive Agents; Bipolar Disorder; Brain; Creatine; Female; Glutamic Acid; Humans; Magn | 2009 |
Chronic treatment with lithium, but not sodium valproate, increases cortical N-acetyl-aspartate concentrations in euthymic bipolar patients.
Topics: Adult; Antidepressive Agents; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Cerebral Cortex; Ch | 2003 |
Decreased N-acetylaspartate in children with familial bipolar disorder.
Topics: Adolescent; Aspartic Acid; Bipolar Disorder; Child; Creatine; Family Health; Female; Humans; Magneti | 2003 |
Oral choline decreases brain purine levels in lithium-treated subjects with rapid-cycling bipolar disorder: a double-blind trial using proton and lithium magnetic resonance spectroscopy.
Topics: Administration, Oral; Antipsychotic Agents; Bipolar Disorder; Brain; Choline; Creatine; Diagnostic a | 2003 |
Creatine monohydrate in resistant depression: a preliminary study.
Topics: Administration, Oral; Adult; Antidepressive Agents; Bipolar Disorder; Brain; Creatine; Diagnostic an | 2007 |
Proton magnetic resonance spectroscopy in youth with severe mood dysregulation.
Topics: Antimanic Agents; Arousal; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Bipolar Dis | 2008 |
Decreased anterior cingulate myo-inositol/creatine spectroscopy resonance with lithium treatment in children with bipolar disorder.
Topics: Adolescent; Area Under Curve; Aspartic Acid; Bipolar Disorder; Child; Creatine; Demography; Drug Adm | 2001 |
75 other studies available for creatine and Affective Psychosis, Bipolar
| Article | Year |
|---|---|
Metabolic abnormalities in the basal ganglia and cerebellum in bipolar disorder: A multi-modal MR study.
Topics: Aspartic Acid; Basal Ganglia; Bipolar Disorder; Cerebellum; Creatine; Cross-Sectional Studies; Human | 2022 |
Elevated choline in dorsolateral prefrontal cortex of lithium responders with bipolar I disorder.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dorsolateral Prefrontal Cortex; Humans; L | 2023 |
Elevated choline in dorsolateral prefrontal cortex of lithium responders with bipolar I disorder.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dorsolateral Prefrontal Cortex; Humans; L | 2023 |
Elevated choline in dorsolateral prefrontal cortex of lithium responders with bipolar I disorder.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dorsolateral Prefrontal Cortex; Humans; L | 2023 |
Elevated choline in dorsolateral prefrontal cortex of lithium responders with bipolar I disorder.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dorsolateral Prefrontal Cortex; Humans; L | 2023 |
Elevated choline in dorsolateral prefrontal cortex of lithium responders with bipolar I disorder.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dorsolateral Prefrontal Cortex; Humans; L | 2023 |
Elevated choline in dorsolateral prefrontal cortex of lithium responders with bipolar I disorder.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dorsolateral Prefrontal Cortex; Humans; L | 2023 |
Elevated choline in dorsolateral prefrontal cortex of lithium responders with bipolar I disorder.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dorsolateral Prefrontal Cortex; Humans; L | 2023 |
Elevated choline in dorsolateral prefrontal cortex of lithium responders with bipolar I disorder.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dorsolateral Prefrontal Cortex; Humans; L | 2023 |
Elevated choline in dorsolateral prefrontal cortex of lithium responders with bipolar I disorder.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dorsolateral Prefrontal Cortex; Humans; L | 2023 |
Altered biochemical metabolism and its lateralization in the cortico-striato-cerebellar circuit of unmedicated bipolar II depression.
Topics: Adult; Aspartic Acid; Basal Ganglia; Bipolar Disorder; Cerebellum; Choline; Creatine; Cross-Sectiona | 2019 |
Altered brain creatine cycle metabolites in bipolar I disorder with childhood abuse: A
Topics: Adolescent; Adult; Adult Survivors of Child Abuse; Bipolar Disorder; Creatine; Female; Gyrus Cinguli | 2021 |
Neurometabolic alterations in bipolar disorder with anxiety symptoms: A proton magnetic resonance spectroscopy study of the prefrontal whiter matter.
Topics: Anxiety; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Humans; Proton Magnetic Resonance Spect | 2021 |
Anterior cingulate cortex neuro-metabolic changes underlying lithium-induced euthymia in bipolar depression: A longitudinal
Topics: Aspartic Acid; Bipolar Disorder; Brain; Choline; Creatine; Gyrus Cinguli; Humans; Inositol; Lithium; | 2021 |
Diagnosis and body mass index effects on hippocampal volumes and neurochemistry in bipolar disorder.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Body Mass Index; Brain; Case-Control Studies; Cr | 2017 |
Biochemical abnormalities in basal ganglia and executive dysfunction in acute- and euthymic-episode patients with bipolar disorder: A proton magnetic resonance spectroscopy study.
Topics: Adult; Aspartic Acid; Basal Ganglia; Biomarkers; Bipolar Disorder; Brain; Brain Chemistry; Case-Cont | 2018 |
Neurochemical differences between bipolar disorder type I and II in superior temporal cortices: A proton magnetic resonance spectroscopy study.
Topics: Adult; Bipolar Disorder; Creatine; Cross-Sectional Studies; Cyclothymic Disorder; Female; Glutamic A | 2018 |
Associations between executive function impairment and biochemical abnormalities in bipolar disorder with suicidal ideation.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Case-Control Studies; Cerebral Cortex; Choline; Corpu | 2018 |
Functional magnetic resonance spectroscopy in patients with schizophrenia and bipolar affective disorder: Glutamate dynamics in the anterior cingulate cortex during a working memory task.
Topics: Adult; Analysis of Variance; Bipolar Disorder; Creatine; Female; Glutamic Acid; Glutamine; Gyrus Cin | 2019 |
Longitudinal proton spectroscopy study of the prefrontal cortex in youth at risk for bipolar disorder before and after their first mood episode.
Topics: Adolescent; Adult; Affective Symptoms; Bipolar Disorder; Child; Child of Impaired Parents; Creatine; | 2019 |
Lamotrigine Therapy and Biomarkers of Cerebral Energy Metabolism in Older Age Bipolar Depression.
Topics: Aged; Aging; Antipsychotic Agents; Aspartic Acid; Biomarkers; Bipolar Disorder; Cerebral Cortex; Cre | 2019 |
Role of glia in prefrontal white matter abnormalities in first episode psychosis or mania detected by diffusion tensor spectroscopy.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Choline; Creatine; Diffusion Tensor Im | 2019 |
Magnetic resonance spectroscopy imaging of lactate in patients with bipolar disorder.
Topics: Adolescent; Adult; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Female; | 2013 |
Neurochemical abnormalities in unmedicated bipolar depression and mania: a 2D 1H MRS investigation.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Creatine; Female; Glutamic Acid; Humans; Image Proces | 2013 |
(1)H-MRS of hippocampus in patients after first manic episode.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Glutamic Acid; Glutamine; Hip | 2014 |
Prospective neurochemical characterization of child offspring of parents with bipolar disorder.
Topics: Adolescent; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Child; Child of Impaired Parents; | 2013 |
Type 2 diabetes mellitus: a potentially modifiable risk factor for neurochemical brain changes in bipolar disorders.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Creatine; Cross-Sectional Studies; Diabetes Mellitus, | 2015 |
Anterior cingulate cortex choline levels in female adolescents with unipolar versus bipolar depression: a potential new tool for diagnosis.
Topics: Adolescent; Analysis of Variance; Bipolar Disorder; Choline; Creatine; Cross-Sectional Studies; Depr | 2014 |
Similarities of biochemical abnormalities between major depressive disorder and bipolar depression: a proton magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Brain; Choline; Creatine; Depressive Disorder, M | 2014 |
Investigation of Heschl's gyrus and planum temporale in patients with schizophrenia and bipolar disorder: a proton magnetic resonance spectroscopy study.
Topics: Adult; Analysis of Variance; Aspartic Acid; Auditory Cortex; Bipolar Disorder; Creatine; Female; Hum | 2015 |
Hippocampal glutamatergic/NMDA receptor functioning in bipolar disorder: A study combining mismatch negativity and proton magnetic resonance spectroscopy.
Topics: Adult; Bipolar Disorder; Creatine; Electroencephalography; Evoked Potentials; Female; Glutamic Acid; | 2015 |
Evidence of altered membrane phospholipid metabolism in the anterior cingulate cortex and striatum of patients with bipolar disorder I: A multi-voxel (1)H MRS study.
Topics: Adult; Aged; Bipolar Disorder; Corpus Striatum; Creatine; Female; Glutamic Acid; Gyrus Cinguli; Huma | 2016 |
Main Effects of Diagnoses, Brain Regions, and their Interaction Effects for Cerebral Metabolites in Bipolar and Unipolar Depressive Disorders.
Topics: Adult; Aspartic Acid; Biomarkers; Bipolar Disorder; Case-Control Studies; Choline; Creatine; Depress | 2016 |
Differential neurometabolite alterations in brains of medication-free individuals with bipolar disorder and those with unipolar depression: a two-dimensional proton magnetic resonance spectroscopy study.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Depressive Disorder; Female; Gyrus Cingul | 2016 |
A comparison of neurometabolites between remitted bipolar disorder and depressed bipolar disorder: A proton magnetic resonance spectroscopy study.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Choline; Creatine; Female; Humans; Mal | 2017 |
Neurochemical alterations in adolescent bipolar depression: a proton magnetic resonance spectroscopy pilot study of the prefrontal cortex.
Topics: Adolescent; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Aspartic Acid; Bipolar Dis | 2008 |
Elevated metabolites within dorsolateral prefrontal cortex in rapid cycling bipolar disorder.
Topics: Adult; Aspartic Acid; Biomarkers; Bipolar Disorder; Brain; Choline; Creatine; Female; Functional Lat | 2009 |
Creatine abnormalities in schizophrenia and bipolar disorder.
Topics: Adult; Bipolar Disorder; Brain; Creatine; Energy Metabolism; Female; Gyrus Cinguli; Humans; Image Pr | 2009 |
Bipolar disorder comorbid with alcoholism: a 1H magnetic resonance spectroscopy study.
Topics: Adult; Age Factors; Alcoholism; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Brain; Comorb | 2010 |
T2 relaxation time abnormalities in bipolar disorder and schizophrenia.
Topics: Adult; Aspartic Acid; Biomarkers; Bipolar Disorder; Brain; Choline; Creatine; Female; Humans; Magnet | 2010 |
Cortical neurochemistry in euthymic patients with bipolar I disorder.
Topics: Adult; Affect; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dominance, Cere | 2009 |
[Application of lamotrigine in bipolar disorder--3T MR spectroscopy follow up (part 1)].
Topics: Antimanic Agents; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Excitatory Amino Acid Antagoni | 2010 |
Association of the brain-derived neurotrophic factor val66met polymorphism with magnetic resonance spectroscopic markers in the human hippocampus: in vivo evidence for effects on the glutamate system.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Creatine; Female; Genetic | 2012 |
Neurochemical alteration in the caudate: implications for the pathophysiology of bipolar disorder.
Topics: Adolescent; Adult; Antidepressive Agents; Aspartic Acid; Bipolar Disorder; Brain Mapping; Caudate Nu | 2011 |
Acute mania is accompanied by elevated glutamate/glutamine levels within the left dorsolateral prefrontal cortex.
Topics: Acute Disease; Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Female; Glutamic Acid; Glu | 2003 |
Lower concentration of hippocampal N-acetylaspartate in familial bipolar I disorder.
Topics: Adult; Ambulatory Care; Aspartic Acid; Axons; Bipolar Disorder; Choline; Creatine; Family; Functiona | 2003 |
Proton magnetic resonance spectroscopy of bipolar disorder versus intermittent explosive disorder in children and adolescents.
Topics: Adolescent; Age Factors; Aspartic Acid; Bipolar Disorder; Child; Choline; Creatine; Diagnosis, Diffe | 2003 |
[ANALYSIS OF THE ACTION OF MD 2028 IN CHRONIC PSYCHOSES BY J.R.WITTENBORN'S PSYCHIATRIC EVALUATION SCALE].
Topics: 17-Ketosteroids; Bipolar Disorder; Butyrophenones; Creatine; Creatinine; Humans; Hypnotics and Sedat | 1964 |
Proton magnetic resonance spectroscopy in first episode psychosis and ultra high-risk individuals.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Brain Mapping; Choline; Creatine; Depressive Dis | 2003 |
Brain metabolic alterations in medication-free patients with bipolar disorder.
Topics: Adult; Ambulatory Care; Bipolar Disorder; Brain; Brain Chemistry; Creatine; Echo-Planar Imaging; Fem | 2004 |
Hippocampal neurochemical pathology in patients at first episode of affective psychosis: a proton magnetic resonance spectroscopic imaging study.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Cerebral Cortex; Choline; Creatine; Depressive D | 2004 |
1H magnetic resonance spectroscopy investigation of the dorsolateral prefrontal cortex in bipolar disorder patients.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Creatine; Diagnostic and Statistical M | 2005 |
Reduced NAA levels in the dorsolateral prefrontal cortex of young bipolar patients.
Topics: Adolescent; Adult; Age Factors; Aspartic Acid; Bipolar Disorder; Child; Choline; Creatine; Female; H | 2005 |
N-acetylaspartate levels in bipolar offspring with and at high-risk for bipolar disorder.
Topics: Adolescent; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Child; Cohort Studies; Creatine; | 2005 |
Differences in brain chemistry in children and adolescents with attention deficit hyperactivity disorder with and without comorbid bipolar disorder: a proton magnetic resonance spectroscopy study.
Topics: Adolescent; Age Factors; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Brain Chem | 2006 |
Hippocampal 1H MRS in first-episode bipolar I patients.
Topics: Adult; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Choline; Creatin | 2006 |
A 1HMRS study of the anterior cingulate gyrus in euthymic bipolar patients.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Female; Gyrus Cinguli; Humans; Lithium; M | 2006 |
Mania, glutamate/glutamine and risperidone in pediatric bipolar disorder: a proton magnetic resonance spectroscopy study of the anterior cingulate cortex.
Topics: Adolescent; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; C | 2007 |
Lithium in breast milk and nursing infants: clinical implications.
Topics: Bipolar Disorder; Blood Urea Nitrogen; Breast Feeding; Creatine; Female; Humans; Infant; Infant, New | 2007 |
Reduced concentrations of N-acetylaspartate (NAA) and the NAA-creatine ratio in the basal ganglia in bipolar disorder: a study using 3-Tesla proton magnetic resonance spectroscopy.
Topics: Adult; Aspartic Acid; Basal Ganglia; Bipolar Disorder; Creatine; Female; Hospitalization; Humans; Ma | 2007 |
Increased anterior cingulate/medial prefrontal cortical glutamate and creatine in bipolar depression.
Topics: Adult; Analysis of Variance; Antidepressive Agents; Bipolar Disorder; Creatine; Evaluation Studies a | 2007 |
Abnormal cellular energy and phospholipid metabolism in the left dorsolateral prefrontal cortex of medication-free individuals with bipolar disorder: an in vivo 1H MRS study.
Topics: Adult; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Creatine; Energy | 2007 |
Low levels of N-acetyl aspartate in the left dorsolateral prefrontal cortex of pediatric bipolar patients.
Topics: Adolescent; Aspartic Acid; Bipolar Disorder; Child; Creatine; Female; Glycerylphosphorylcholine; Hum | 2007 |
Brain-derived neurotrophic factor val66met polymorphism affects prefrontal energy metabolism in bipolar disorder.
Topics: Adult; Amino Acid Substitution; Aspartic Acid; Bipolar Disorder; Brain-Derived Neurotrophic Factor; | 2007 |
Dorsolateral prefrontal N-acetyl-aspartate concentration in male patients with chronic schizophrenia and with chronic bipolar disorder.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Cerebrospinal Fluid; Choline; Chronic Disease; Creatine; Fou | 2007 |
Dopamine transporter genotype influences N-acetyl-aspartate in the left putamen.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dominance, Cerebral; Dopamine Plasma Memb | 2009 |
Metabolic alterations in medication-free patients with bipolar disorder: a 3T CSF-corrected magnetic resonance spectroscopic imaging study.
Topics: Adolescent; Adult; Aspartic Acid; Basal Ganglia; Bipolar Disorder; Brain; Case-Control Studies; Caud | 2008 |
Neurochemical pathology in hippocampus in euthymic patients with bipolar I disorder.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dysthymic Disorder; Female; Hippocampus; | 2008 |
Metabonomic analysis identifies molecular changes associated with the pathophysiology and drug treatment of bipolar disorder.
Topics: Adult; Analysis of Variance; Animals; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Case-Contro | 2009 |
Glutamate as a spectroscopic marker of hippocampal structural plasticity is elevated in long-term euthymic bipolar patients on chronic lithium therapy and correlates inversely with diurnal cortisol.
Topics: Adult; Aged; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Choline; Circa | 2009 |
Biochemical changes in the cingulum in patients with schizophrenia and chronic bipolar disorder.
Topics: Adult; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Choline; Chronic Disease; Creatine; Fe | 2008 |
Reduction of brain phosphocreatine in bipolar II disorder detected by phosphorus-31 magnetic resonance spectroscopy.
Topics: Adenosine Triphosphate; Adult; Aged; Analysis of Variance; Bipolar Disorder; Creatine; Creatine Kina | 1994 |
Quantitative proton magnetic resonance spectroscopy of the basal ganglia in patients with affective disorders.
Topics: Adult; Aspartic Acid; Basal Ganglia; Bipolar Disorder; Choline; Creatine; Depressive Disorder; Femal | 1998 |
Proton magnetic resonance spectroscopy of the lenticular nuclei in bipolar I affective disorder.
Topics: Adult; Age Factors; Aspartic Acid; Bipolar Disorder; Brain Mapping; Cell Survival; Choline; Corpus S | 1998 |
Increased cerebrospinal fluid glutamine levels in depressed patients.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Bipolar Disorder; Case-Control Studies; Cre | 2000 |
Proton MR spectroscopy in children with bipolar affective disorder: preliminary observations.
Topics: Aspartic Acid; Basal Ganglia; Bipolar Disorder; Child; Choline; Creatine; Energy Metabolism; Frontal | 2000 |
Increased thalamic N-acetylaspartate in male patients with familial bipolar I disorder.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Humans; Hypertrophy; Magnetic Resonance S | 2001 |
Proton magnetic resonance spectroscopy of the brain in schizophrenic and affective patients.
Topics: Adult; Aspartic Acid; Basal Ganglia; Bipolar Disorder; Choline; Creatine; Depressive Disorder; Energ | 1992 |
[Studies on relations between the central nervous system and adrenal cortex activity. I. Adrenal cortex function in manic-depressive psychoses].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Adult; Bipolar Disorder; Cr | 1965 |
The variability of creatinine excretion in normal subjects, mental patients and pregnant women.
Topics: Bipolar Disorder; Creatine; Creatinine; Diet; Dietary Proteins; Female; Humans; Kidney; Male; Meat; | 1969 |
Muscle abnormalities in acute psychoses.
Topics: Acute Disease; Adolescent; Adult; Biopsy; Bipolar Disorder; Creatine; Creatine Kinase; Creatinine; F | 1970 |
The effect of an altered time regime on biological rhythms in a 48-hour periodic psychosis.
Topics: 17-Ketosteroids; Adult; Bipolar Disorder; Body Temperature; Calcium; Chlorides; Circadian Rhythm; Cr | 1968 |
Catechloamine excretion in manic-depressive and schizophrenic psychosis and its relationship to symptomatology.
Topics: Adult; Bipolar Disorder; Creatine; Dopamine; Epinephrine; Humans; Middle Aged; Norepinephrine; Psych | 1966 |