creatine and ADDH
creatine has been researched along with ADDH in 27 studies
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to investigate the anterior cingulate cortex (ACC) glutamate/glutamine (Glx) to creatine ratio (Glx/Cr) in two groups of children with Bipolar Disorder (BPD): those exhibiting manic symptoms requiring treatment and those being stably treated with the atypical antipsychotic risperidone." | 7.74 | Mania, glutamate/glutamine and risperidone in pediatric bipolar disorder: a proton magnetic resonance spectroscopy study of the anterior cingulate cortex. ( Aleardi, M; Biederman, J; Dougherty, M; Hammerness, P; Harpold, T; Lyoo, IK; Mick, E; Moore, CM; Randall, E; Renshaw, PF; Wardrop, M; Wozniak, J, 2007) |
| "The purpose of this study was to investigate the anterior cingulate cortex (ACC) glutamate/glutamine (Glx) to creatine ratio (Glx/Cr) in two groups of children with Bipolar Disorder (BPD): those exhibiting manic symptoms requiring treatment and those being stably treated with the atypical antipsychotic risperidone." | 3.74 | Mania, glutamate/glutamine and risperidone in pediatric bipolar disorder: a proton magnetic resonance spectroscopy study of the anterior cingulate cortex. ( Aleardi, M; Biederman, J; Dougherty, M; Hammerness, P; Harpold, T; Lyoo, IK; Mick, E; Moore, CM; Randall, E; Renshaw, PF; Wardrop, M; Wozniak, J, 2007) |
| "The authors' goal was to investigate phosphatidylinositol and glutamatergic metabolism in the anterior cingulate cortex of children and adolescents with attention deficit hyperactivity disorder (ADHD) alone, children with ADHD plus bipolar disorder, and children with no axis I diagnosis." | 3.73 | Differences in brain chemistry in children and adolescents with attention deficit hyperactivity disorder with and without comorbid bipolar disorder: a proton magnetic resonance spectroscopy study. ( Aleardi, M; Biederman, J; Dougherty, M; Hammerness, P; Harpold, T; Mick, E; Moore, CM; Randall, E; Renshaw, PF; Wardrop, M; Wozniak, J, 2006) |
Research
Studies (27)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (44.44) | 29.6817 |
| 2010's | 13 (48.15) | 24.3611 |
| 2020's | 2 (7.41) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Bakhshi, S | 2 |
| Tehrani-Doost, M | 2 |
| Batouli, SAH | 2 |
| Goryunova, AV | 1 |
| Shevchenko, YS | 1 |
| Goryunov, AV | 1 |
| Husarova, V | 2 |
| Bittsansky, M | 2 |
| Ondrejka, I | 2 |
| Dobrota, D | 2 |
| Liso Navarro, AA | 1 |
| Sikoglu, EM | 1 |
| Heinze, CR | 1 |
| Rogan, RC | 1 |
| Russell, VA | 1 |
| King, JA | 1 |
| Moore, CM | 3 |
| Unal, GA | 3 |
| Kenar, AN | 1 |
| Herken, H | 3 |
| Kiroglu, Y | 3 |
| Inci Kenar, AN | 2 |
| Güler, H | 1 |
| Albuz, B | 1 |
| Erdal, ME | 1 |
| Dickstein, DP | 2 |
| Towbin, KE | 2 |
| Van Der Veen, JW | 2 |
| Rich, BA | 1 |
| Brotman, MA | 1 |
| Knopf, L | 2 |
| Onelio, L | 1 |
| Pine, DS | 2 |
| Leibenluft, E | 2 |
| Ferreira, PE | 1 |
| Palmini, A | 1 |
| Bau, CH | 1 |
| Grevet, EH | 1 |
| Hoefel, JR | 1 |
| Rohde, LA | 1 |
| Anés, M | 1 |
| Ferreira, EE | 1 |
| Belmonte-de-Abreu, P | 1 |
| Yang, P | 1 |
| Wu, MT | 1 |
| Dung, SS | 1 |
| Ko, CW | 1 |
| Rüsch, N | 1 |
| Boeker, M | 1 |
| Büchert, M | 1 |
| Glauche, V | 1 |
| Bohrmann, C | 1 |
| Ebert, D | 3 |
| Lieb, K | 1 |
| Hennig, J | 2 |
| Tebartz Van Elst, L | 2 |
| Perlov, E | 2 |
| Tebarzt van Elst, L | 1 |
| Buechert, M | 2 |
| Maier, S | 1 |
| Matthies, S | 1 |
| Hesslinger, B | 2 |
| Philipsen, A | 2 |
| Buschkuehl, M | 1 |
| Jaeggi, SM | 1 |
| Arcos-Burgos, M | 1 |
| Londoño, AC | 1 |
| Pineda, DA | 1 |
| Lopera, F | 1 |
| Palacio, JD | 1 |
| Arbelaez, A | 1 |
| Acosta, MT | 1 |
| Vélez, JI | 1 |
| Castellanos, FX | 1 |
| Muenke, M | 1 |
| Tafazoli, S | 1 |
| O'Neill, J | 1 |
| Bejjani, A | 1 |
| Ly, R | 1 |
| Salamon, N | 1 |
| McCracken, JT | 1 |
| Alger, JR | 1 |
| Levitt, JG | 1 |
| Courvoisie, H | 1 |
| Hooper, SR | 1 |
| Fine, C | 1 |
| Kwock, L | 1 |
| Castillo, M | 1 |
| Sparkes, SJ | 1 |
| MacMaster, FP | 2 |
| Carrey, NC | 1 |
| Biederman, J | 2 |
| Wozniak, J | 2 |
| Mick, E | 2 |
| Aleardi, M | 2 |
| Wardrop, M | 2 |
| Dougherty, M | 2 |
| Harpold, T | 2 |
| Hammerness, P | 2 |
| Randall, E | 2 |
| Renshaw, PF | 2 |
| Margari, L | 1 |
| Ventura, P | 1 |
| Portoghese, C | 1 |
| Presicci, A | 1 |
| Buttiglione, M | 1 |
| Di Cuonzo, F | 1 |
| Lyoo, IK | 1 |
| Ahrendts, J | 1 |
| Feige, B | 1 |
| Bubl, E | 1 |
| Carrey, NJ | 1 |
| Gaudet, L | 1 |
| Schmidt, MH | 1 |
| Yeo, RA | 1 |
| Hill, D | 1 |
| Campbell, R | 1 |
| Vigil, J | 1 |
| Brooks, WM | 1 |
| Jin, Z | 1 |
| Zang, YF | 1 |
| Zeng, YW | 1 |
| Zhang, L | 1 |
| Wang, YF | 1 |
Clinical Trials (2)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| 1/2-MC4R Genotype and Pediatric Antipsychotic Drug- Induced Weight Gain[NCT01844700] | Phase 4 | 14 participants (Actual) | Interventional | 2013-07-31 | Terminated (stopped due to very slow recruitment, no sufficient results) | ||
| Measuring Glutamate and GABA Brain Levels in Adults With Attention Deficit Hyperactivity Disorder (ADHD) Using Magnetic Resonance Spectroscopy (MRS)[NCT04823364] | 60 participants (Anticipated) | Interventional | 2022-10-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Trial Outcomes
Percent Weight Change Compared to Baseline Weight
(NCT01844700)
Timeframe: baseline to week 12
| Intervention | percentage of weight change (Mean) |
|---|---|
| Ziprasidone | 11.58 |
| Aripiprazole, Quetiapine, Risperidone | 5.66 |
BMI Percentile
(NCT01844700)
Timeframe: baseline to week 12
| Intervention | BMI percentile (Mean) | |
|---|---|---|
| baseline | week 12 (n=1, n=2) | |
| Aripiprazole, Quetiapine, Risperidone | 37.67 | 62.5 |
| Ziprasidone | 32 | 59 |
BMI Z-scores
(NCT01844700)
Timeframe: baseline to week 12
| Intervention | BMI z-score (Mean) | |
|---|---|---|
| baseline | week 12 (n=1, n=2) | |
| Aripiprazole, Quetiapine, Risperidone | -0.37 | 0.38 |
| Ziprasidone | -0.51 | 0.22 |
Weight Change
(NCT01844700)
Timeframe: baseline to week 12
| Intervention | lbs (Mean) | |
|---|---|---|
| baseline | week 12 (n=1,2) | |
| Aripiprazole, Quetiapine, Risperidone | 118.5 | 141 |
| Ziprasidone | 120.5 | 151 |
Reviews
2 reviews available for creatine and ADDH
| Article | Year |
|---|---|
[Cogitum in children's neurology and psychiatry (experience in the practical use)].
Topics: Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Brain; Child; Choline; Creatine; Human | 2019 |
Improving intelligence: a literature review.
Topics: Achievement; Adolescent; Adult; Aged; Attention Deficit Disorder with Hyperactivity; Central Nervous | 2010 |
Trials
2 trials available for creatine and ADDH
| Article | Year |
|---|---|
Randomized double-blind placebo-controlled trial of lithium in youths with severe mood dysregulation.
Topics: Adolescent; Antimanic Agents; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Bipolar | 2009 |
Proton magnetic resonance spectroscopy in youth with severe mood dysregulation.
Topics: Antimanic Agents; Arousal; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Bipolar Dis | 2008 |
Other Studies
23 other studies available for creatine and ADDH
| Article | Year |
|---|---|
Evaluation of fronto-cerebellar neurometabolites in youth with ADHD compared to the healthy group and their associations with cognitive and behavioral characteristics: A proton magnetic spectroscopy study.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Cerebellum; Child; Cognition; Creatine; H | 2022 |
Fronto-Cerebellar Neurometabolite Alterations After Methylphenidate in Children and Adolescents With ADHD: A Proton Magnetic Resonance Spectroscopy Study.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Brain; Central Nervous System Stimulants; | 2023 |
Prefrontal grey and white matter neurometabolite changes after atomoxetine and methylphenidate in children with attention deficit/hyperactivity disorder: a (1)H magnetic resonance spectroscopy study.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Aspartic Acid; Atomoxetine Hydrochloride; Attention; Atten | 2014 |
Effect of diet on brain metabolites and behavior in spontaneously hypertensive rats.
Topics: Animals; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Brain; Creatine; Dietary Fats | 2014 |
Correlations of ADHD symptoms with neurometabolites measured by 1H magnetic resonance spectroscopy.
Topics: Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Child; Choline; Creatine; Female; Glut | 2014 |
Association of adult attention deficit hyperactivity disorder subtypes and response to methylphenidate HCL treatment: A magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Central Nervous Sys | 2015 |
Relationship between the DAT1 gene and the effects of methylphenidate administration in adult attention deficit hyperactivity disorder: a magnetic resonance spectroscopy study.
Topics: Administration, Oral; Adolescent; Adult; Alleles; Aspartic Acid; Attention Deficit Disorder with Hyp | 2016 |
Effects of methylphenidate treatment on the cerebellum in adult attention-deficit hyperactivity disorder: a magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Central Nervous Sys | 2017 |
Differentiating attention-deficit/hyperactivity disorder inattentive and combined types: a (1)H-magnetic resonance spectroscopy study of fronto-striato-thalamic regions.
Topics: Adolescent; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Choline; Corpus Striatum; | 2009 |
Short-TE proton magnetic resonance spectroscopy investigation in adolescents with attention-deficit hyperactivity disorder.
Topics: Adolescent; Analysis of Variance; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Chil | 2010 |
Neurochemical alterations in women with borderline personality disorder and comorbid attention-deficit hyperactivity disorder.
Topics: Adult; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Borderline Personality Disorder | 2010 |
H¹-MR-spectroscopy of cerebellum in adult attention deficit/hyperactivity disorder.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Case-Control Studies; Cerebellar Cortex; Cereb | 2010 |
Analysis of brain metabolism by proton magnetic resonance spectroscopy (1H-MRS) in attention-deficit/hyperactivity disorder suggests a generalized differential ontogenic pattern from controls.
Topics: Adolescent; Adult; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Brain; Case-Control | 2012 |
1H MRSI of middle frontal gyrus in pediatric ADHD.
Topics: Analysis of Variance; Attention Deficit Disorder with Hyperactivity; Child; Choline; Creatine; Femal | 2013 |
Neurometabolic functioning and neuropsychological correlates in children with ADHD-H: preliminary findings.
Topics: Aspartic Acid; Attention; Attention Deficit Disorder with Hyperactivity; Brain Chemistry; Case-Contr | 2004 |
Proton magnetic resonance spectroscopy and cognitive function in pediatric attention-deficit/hyperactive disorder.
Topics: Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Brain Stem; Child; Choline; Cognition | 2004 |
Differences in brain chemistry in children and adolescents with attention deficit hyperactivity disorder with and without comorbid bipolar disorder: a proton magnetic resonance spectroscopy study.
Topics: Adolescent; Age Factors; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Brain Chem | 2006 |
Brain magnetic resonance spectroscopy in Sydenham's chorea and ADHD.
Topics: Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Brain; Child; Choline; Chorea; Creatin | 2006 |
Mania, glutamate/glutamine and risperidone in pediatric bipolar disorder: a proton magnetic resonance spectroscopy study of the anterior cingulate cortex.
Topics: Adolescent; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; C | 2007 |
Reduced cingulate glutamate/glutamine-to-creatine ratios in adult patients with attention deficit/hyperactivity disorder -- a magnet resonance spectroscopy study.
Topics: Adult; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Choline; Creatine; Dominance, C | 2007 |
Striatal creatine and glutamate/glutamine in attention-deficit/hyperactivity disorder.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Choline; Co | 2007 |
Developmental instability and working memory ability in children: a magnetic resonance spectroscopy investigation.
Topics: Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Child; Choline; Creatine; Energy Metab | 2000 |
Striatal neuronal loss or dysfunction and choline rise in children with attention-deficit hyperactivity disorder: a 1H-magnetic resonance spectroscopy study.
Topics: Adolescent; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Cell Death; Child; Choline | 2001 |