Page last updated: 2024-08-26

cp 96345 and Muscle Contraction

cp 96345 has been researched along with Muscle Contraction in 52 studies

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's47 (90.38)18.2507
2000's3 (5.77)29.6817
2010's2 (3.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cardoso, CRB; de Oliveira, AM; do Vale, BN; Gimenes, LR; Gomes, MS; Moreira, JD; Pernomian, L1
Li, C; Micci, MA; Murthy, KS; Pasricha, PJ1
Chien, CT; Hsu, SM; Lai, MK; Lin, TB; Yu, HJ1
Gallantine, EL; Meert, TF1
Longmore, J; Razzaque, Z1
Hay, DW; Hubbard, WC; Undem, BJ1
Akkermans, LM; Briejer, MR; Lefebvre, RA; Meulemans, AL; Schuurkes, JA1
Boccio, D; Carruette, A; Garret, C; Montier, F; Moussaoui, S1
Hill, RG; Longmore, J; Razzaque, Z; Shaw, D1
Corsi, M; Gaviraghi, G; Oliosi, B; Palea, S; Pietra, C; Sugg, E; Trist, DG; Van Amsterdam, FT1
Gomi, Y; Mizuno, K; Suzuki, N1
Barthó, L; Lefebvre, R1
Lefebvre, RA; Smits, GJ1
Killingsworth, CR; Shore, SA1
Giuliani, S; Maggi, CA; Meini, S; Patacchini, R1
Iwata, T; Kamiya, H; Matsumoto, H; Ohno, M; Saito, R; Shimohigashi, Y; Takano, Y1
Bertrand, C; Bunnett, NW; Debas, HT; Geppetti, P; Huber, O; Nadel, JA; Pellegrini, CA1
Honda, K; Kamiya, H; Nakayama, Y; Saigo, A; Saito, R; Takano, Y1
Giachetti, A; Giuliani, S; Maggi, CA; Patacchini, R1
Bartho, L; Giuliani, S; Maggi, CA; Santicioli, P1
Birder, LA; Fukuoka, H; Kawatani, M; Matsumoto, G; Misaki, A; Suzuki, S; Yoshiyama, M1
Boyle, SJ; Guard, S; McKnight, AT; Tang, KW; Watling, KJ; Woodruff, GN1
Carraway, RE; Mitra, SP1
Hodgson, WC; Hopkins, BJ; Sutherland, SK1
Hill, JM; Kaufman, MP; Pickar, JG1
Håkanson, R; Strichartz, GR; Tung, SR; Wang, ZY1
Benoit, PA; Constantine, JW; Knight, DR; Lebel, WS; Wolfgang, EA; Woody, HA1
Bertrand, C; Bunnett, NW; Debas, HT; Geppetti, P; Huber, O; Nadel, JA; Nakazato, P; Pellegrini, CA1
Barnes, JC; Hawcock, AB1
Briejer, MR; Schuurkes, JA1
Galligan, JJ; Yunker, AM1
Cirillo, R; Conte, B; Manzini, S; Parlani, M1
Gustafsson, LE; Olgart, C; Wiklund, NP1
Holst, JJ; Rasmussen, TN; Schmidt, PT1
Hand, GA; Wilson, LB1
Inoue, M; Nakayamada, H; Tokuyama, S; Ueda, H1
Broussard, DL; Feng, HS; Ouyang, A1
Freire-Maia, L; Leite, R; Matos, IM; Teixeira, MM1
Lu, ZY; Wei, EQ; Zhang, WP1
Allescher, HD; Hahn, A; Storr, M1
Clingan, CA; Delay-Goyet, P; Franco-Cereceda, A; Gonsalves, SF; Lowe, JA; Lundberg, JM1
Hill, RG; Longmore, J1
Ellis, JL; Undem, BJ1
Buckner, CK; Renzetti, LM; Shenvi, A1
Maggi, CA; Patacchini, R1
Hess, HJ; Kanai, Y; Lowe, JA; Nagahisa, A; Suga, O; Taniguchi, K; Tsuchiya, M1
Håkanson, R; Wang, ZY1
Fujii, T; Kiyotoh, S; Maeda, Y; Morimoto, H; Murai, M; Nishikawa, M; Yamaoka, M1
Griesbacher, T; Legat, FJ; Lembeck, F1
Alouan, LA; Armour, CL; Badgery-Parker, T; Black, JL; Burcher, E; Diment, LM; Johnson, PR1
Constantine, JW; Desai, MC; Drozda, SE; Lebel, WS; Longo, KP; Lowe, JA; Snider, RM; Spencer, RW; Vinick, FJ; Woody, HA1
Folkers, K; Håkanson, R; Wang, ZY1

Other Studies

52 other study(ies) available for cp 96345 and Muscle Contraction

ArticleYear
Endothelinergic Contractile Hyperreactivity in Rat Contralateral Carotid to Balloon Injury: Integrated Role for ET
    BioMed research international, 2017, Volume: 2017

    Topics: Acridines; Animals; Biphenyl Compounds; Calcium; Carotid Arteries; Carotid Artery Injuries; Cyclic N-Oxides; Endothelin-1; Endothelium; Male; Muscle Contraction; Oligopeptides; Peptides, Cyclic; Piperidines; Rats; Receptor, Endothelin A; Spin Labels; Superoxides; Vasoconstriction

2017
Substance P is essential for maintaining gut muscle contractility: a novel role for coneurotransmission revealed by botulinum toxin.
    American journal of physiology. Gastrointestinal and liver physiology, 2014, May-15, Volume: 306, Issue:10

    Topics: Acetylcholine; Animals; Biphenyl Compounds; Botulinum Toxins; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Myosin Light Chains; Pyloric Antrum; Pylorus; Rats; Receptors, Neurokinin-1; Substance P

2014
Substance P via NK1 receptor facilitates hyperactive bladder afferent signaling via action of ROS.
    American journal of physiology. Renal physiology, 2003, Volume: 284, Issue:4

    Topics: Animals; Benzamides; Biphenyl Compounds; Cell Adhesion Molecules; Dose-Response Relationship, Drug; Drug Administration Routes; Electric Stimulation; Female; Free Radical Scavengers; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Pelvis; Piperidines; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, Neurokinin-1; Reflex, Abnormal; Signal Transduction; Sodium Chloride; Substance P; Superoxide Dismutase; Urinary Bladder; Urinary Bladder, Neurogenic; Urination; Visceral Afferents

2003
Attenuation of the gerbil writhing response by mu-, kappa- and delta-opioids, and NK-1, -2 and -3 receptor antagonists.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 79, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Abdomen; Acetic Acid; Analgesics, Opioid; Animals; Behavior, Animal; Biphenyl Compounds; Butanols; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Fentanyl; Gerbillinae; Malates; Morphine; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Pain Measurement; Piperidines; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tetrazoles

2004
Comparison of the effects of (+/-) CP 96,345 and L-668,169 on neurokinin receptor mediated responses in rat and guinea-pig isolated tissues.
    Neuropeptides, 1993, Volume: 25, Issue:3

    Topics: Animals; Biphenyl Compounds; Eledoisin; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Neurokinin-1 Receptor Antagonists; Organ Specificity; Peptide Fragments; Peptides, Cyclic; Portal Vein; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Species Specificity; Substance P; Urinary Bladder

1993
Relative contributions of direct and indirect mechanisms mediating endothelin-induced contraction of guinea-pig trachea.
    British journal of pharmacology, 1993, Volume: 110, Issue:3

    Topics: Animals; Benzamides; Biphenyl Compounds; Capsaicin; Dicarboxylic Acids; Endothelins; Epithelium; Guinea Pigs; Histamine Release; In Vitro Techniques; Kinetics; Leukotriene Antagonists; Male; Muscle Contraction; Neurokinin A; Piperidines; Prostaglandins; Receptors, Tachykinin; SRS-A; Tetrodotoxin; Trachea

1993
Substance P-induced contractions of the guinea-pig proximal colon through stimulation of post-junctional tachykinin NK1 receptors.
    European journal of pharmacology, 1993, Nov-30, Volume: 250, Issue:1

    Topics: Androstanes; Androstenes; Animals; Benzimidazoles; Biphenyl Compounds; Colon; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Neuromuscular Junction; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P

1993
Antagonism of substance P and related peptides by RP 67580 and CP-96,345, at tachykinin NK1 receptor sites, in the rat urinary bladder.
    European journal of pharmacology, 1994, Jan-04, Volume: 251, Issue:1

    Topics: Animals; Biphenyl Compounds; Blood Proteins; Female; Hypnotics and Sedatives; In Vitro Techniques; Indoles; Isoindoles; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P; Urinary Bladder

1994
Differences in the effects of NK1-receptor antagonists, (+/-)-CP 96,345 and CP 99,994, on agonist-induced responses in guinea-pig trachea.
    British journal of pharmacology, 1994, Volume: 112, Issue:1

    Topics: Animals; Biphenyl Compounds; Guinea Pigs; In Vitro Techniques; Indoles; Isoindoles; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Pyrrolidonecarboxylic Acid; Substance P; Trachea

1994
A further analysis of the contraction induced by activation of cholecystokinin A receptors in guinea pig isolated ileum longitudinal muscle-myenteric plexus.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:2

    Topics: Animals; Atropine; Biphenyl Compounds; Drug Interactions; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Neuromuscular Junction; Peptide Fragments; Peptides, Cyclic; Physalaemin; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Substance P; Tetragastrin; Tetrodotoxin

1994
Tachykinin-induced contractions in the circular muscle of guinea pig ileum.
    Japanese journal of pharmacology, 1994, Volume: 65, Issue:3

    Topics: Animals; Atropine; Biphenyl Compounds; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Hypnotics and Sedatives; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Peptides, Cyclic; Rats; Structure-Activity Relationship; Substance P; Tachykinins; Tetrodotoxin

1994
Nitric oxide induces acetylcholine-mediated contractions in the guinea-pig small intestine.
    Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 350, Issue:5

    Topics: Acetylcholine; Animals; Atropine; Biphenyl Compounds; Dose-Response Relationship, Drug; Guinea Pigs; Hexamethonium; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Substance P; Tetrodotoxin

1994
Tachykinin receptors involved in the contractile effect of the natural tachykinins in the rat gastric fundus.
    Journal of autonomic pharmacology, 1994, Volume: 14, Issue:6

    Topics: Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Female; Gastric Fundus; Indoles; Isoindoles; Male; Methacholine Chloride; Muscle Contraction; Neurokinin A; Neurokinin B; Peptide Fragments; Peptides, Cyclic; Rats; Receptors, Tachykinin; Substance P; Tachykinins

1994
Tachykinin receptors mediating contraction of guinea pig lung strips.
    Regulatory peptides, 1995, May-30, Volume: 57, Issue:2

    Topics: Acetylcholine; Animals; Benzamides; Biphenyl Compounds; Dipeptides; Guinea Pigs; In Vitro Techniques; Lung; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Tachykinin; Substance P; Trachea

1995
Evidence for the presence of a septide-sensitive tachykinin receptor in the circular muscle of the guinea-pig ileum.
    European journal of pharmacology, 1993, Apr-28, Volume: 235, Issue:2-3

    Topics: Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscles; Neurokinin A; Peptide Fragments; Pyrrolidonecarboxylic Acid; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Tachykinins

1993
Receptor-mediated specific biological activity of a beta-amyloid protein fragment for NK-1 substance P receptors.
    Biochemical and biophysical research communications, 1993, Jun-15, Volume: 193, Issue:2

    Topics: Amino Acid Sequence; Amyloid beta-Peptides; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Kinetics; Male; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P

1993
Tachykinins contract the circular muscle of the human esophageal body in vitro via NK2 receptors.
    Gastroenterology, 1993, Volume: 105, Issue:4

    Topics: Adolescent; Adult; Aged; Atropine; Benzamides; Biphenyl Compounds; Carbachol; Dose-Response Relationship, Drug; Esophagus; Glycopeptides; Humans; Isometric Contraction; Middle Aged; Muscle Contraction; Muscle, Smooth; Neprilysin; Neurokinin A; Neurokinin B; Piperidines; Receptors, Tachykinin; Substance P; Tachykinins; Tetrodotoxin

1993
Role of NK-1 receptor in central cardiovascular regulation in rats: studies on a novel non-peptide antagonist, CP-96,345, of substance P NK-1 receptor.
    Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2

    Topics: Animals; Biphenyl Compounds; Blood Pressure; Cerebral Ventricles; Heart Rate; Hypnotics and Sedatives; Injections, Intraventricular; Male; Muscle Contraction; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Rats; Receptors, Neurokinin-1; Substance P; Tachykinins; Vas Deferens

1993
In vivo and in vitro activity of SR 48,968, a non-peptide tachykinin NK-2 receptor antagonist.
    Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2

    Topics: Animals; Benzamides; Biphenyl Compounds; Blood Pressure; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Piperidines; Rats; Receptors, Neurokinin-2; Saliva; Substance P; Sulfones; Urinary Bladder

1993
Tachykinin NK-1 and NK-2 receptors in the circular muscle of the guinea-pig proximal colon.
    Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2

    Topics: Animals; Benzamides; Biphenyl Compounds; Colon; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Peptides, Cyclic; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Sulfones; Tetrodotoxin

1993
Intrathecal administration of NK1 receptor antagonist, CP96345, inhibits the micturition reflex in the rat.
    Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2

    Topics: Animals; Biphenyl Compounds; Female; Injections, Spinal; Male; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Neurokinin-1; Reflex; Spinal Cord; Substance P; Urinary Bladder; Urination

1993
The interaction of the NK1 receptor antagonist CP-96,345 with L-type calcium channels and its functional consequences.
    British journal of pharmacology, 1993, Volume: 110, Issue:1

    Topics: Animals; Biphenyl Compounds; Calcium Channels; Cerebral Cortex; Diltiazem; Guinea Pigs; In Vitro Techniques; Male; Membranes; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Neurokinin-1 Receptor Antagonists; Nimodipine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Stereoisomerism; Substance P; Succinimides; Trachea

1993
Binding and biologic activity of neurotensin in guinea pig ileum.
    Peptides, 1994, Volume: 15, Issue:8

    Topics: Adenine Nucleotides; Amino Acid Sequence; Animals; Atropine; Biphenyl Compounds; Cell Membrane; Dose-Response Relationship, Drug; Dynorphins; Guanine Nucleotides; Guinea Pigs; Hydrogen-Ion Concentration; Hypnotics and Sedatives; Ileum; In Vitro Techniques; Kinetics; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neostigmine; Neurotensin; Physostigmine; Receptors, Neurotensin; Structure-Activity Relationship

1994
Pharmacological studies of stonefish (Synanceja trachynis) venom.
    Toxicon : official journal of the International Society on Toxinology, 1994, Volume: 32, Issue:10

    Topics: Animals; Biphenyl Compounds; Blood Pressure; Captopril; Chromones; Dose-Response Relationship, Drug; Fish Venoms; Fishes; Guinea Pigs; Heptanoic Acids; Histamine; Ileum; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Male; Mecamylamine; Muscle Contraction; Muscle, Smooth; Phospholipases A; Phospholipases A2; Quinacrine; Rats; Receptors, Thromboxane; Serotonin; SRS-A; Tetrazoles; Vas Deferens

1994
Blockade of non-NMDA receptors attenuates reflex pressor response to static contraction.
    The American journal of physiology, 1994, Volume: 266, Issue:5 Pt 2

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biphenyl Compounds; Blood Pressure; Cats; Heart Rate; Hypnotics and Sedatives; Injections, Spinal; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Piperazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Time Factors

1994
Non-specific actions of the non-peptide tachykinin receptor antagonists, CP-96,345, RP 67580 and SR 48968, on neurotransmission.
    British journal of pharmacology, 1994, Volume: 111, Issue:1

    Topics: Action Potentials; Anesthetics, Local; Animals; Benzamides; Biphenyl Compounds; Bupivacaine; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Indoles; Iris; Isoindoles; Male; Muscle Contraction; Muscle, Smooth; Piperidines; Procaine; Rabbits; Rana catesbeiana; Receptors, Tachykinin; Sciatic Nerve; Synaptic Transmission; Vas Deferens

1994
Cardiovascular effects of CP-96,345, a non-peptide blocker of tachykinin NK1 receptors.
    European journal of pharmacology, 1994, Feb-11, Volume: 252, Issue:3

    Topics: Animals; Biphenyl Compounds; Blood Pressure; Calcium; Calcium Channel Blockers; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neurokinin-1 Receptor Antagonists; Portal Vein; Rats; Rats, Sprague-Dawley; Vasoconstriction

1994
Tachykinins mediate contraction of the human lower esophageal sphincter in vitro via activation of NK2 receptors.
    European journal of pharmacology, 1993, Aug-03, Volume: 239, Issue:1-3

    Topics: Benzamides; Biphenyl Compounds; Dose-Response Relationship, Drug; Esophagogastric Junction; Glycopeptides; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Neprilysin; Neurokinin A; Neurokinin B; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Tachykinins

1993
Pharmacological characterization of the contractile responses to angiotensin analogues in guinea-pig isolated longitudinal muscle of small intestine.
    British journal of pharmacology, 1993, Volume: 108, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atropine; Biphenyl Compounds; Guinea Pigs; Hypnotics and Sedatives; Imidazoles; In Vitro Techniques; Intestine, Small; Losartan; Male; Muscle Contraction; Muscle, Smooth; Pyridines; Tetrazoles; Tetrodotoxin

1993
5-HT3 and 5-HT4 receptors and cholinergic and tachykininergic neurotransmission in the guinea-pig proximal colon.
    European journal of pharmacology, 1996, Jul-18, Volume: 308, Issue:2

    Topics: Animals; Biphenyl Compounds; Colon; Dioxanes; Dose-Response Relationship, Drug; Drug Interactions; Female; Granisetron; Guinea Pigs; In Vitro Techniques; Interneurons; Male; Motor Neurons; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists

1996
Endogenous NO inhibits NANC but not cholinergic neurotransmission to circular muscle of guinea pig ileum.
    The American journal of physiology, 1996, Volume: 271, Issue:5 Pt 1

    Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apamin; Bethanechol; Biphenyl Compounds; Electric Stimulation; Guanethidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Neurokinin-1 Receptor Antagonists; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Scopolamine; Substance P; Synaptic Transmission; Tetrodotoxin; Vasoactive Intestinal Peptide

1996
Characterization of tachykinin NK2 receptor on dog proximal colon. Antagonism by MEN 10,627 and SR 48,968.
    European journal of pharmacology, 1996, Dec-30, Volume: 318, Issue:2-3

    Topics: Animals; Benzamides; Biphenyl Compounds; Colon; Dogs; Dose-Response Relationship, Drug; Gastrointestinal Motility; In Vitro Techniques; Muscle Contraction; Peptides, Cyclic; Piperidines; Receptors, Neurokinin-2

1996
Blockade of nitric oxide-evoked smooth muscle contractions by an inhibitor of guanylyl cyclase.
    Neuroreport, 1997, Oct-20, Volume: 8, Issue:15

    Topics: Animals; Biphenyl Compounds; Enzyme Inhibitors; Guanylate Cyclase; Guinea Pigs; In Vitro Techniques; Intestine, Small; Male; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Nitric Oxide; Signal Transduction; Substance P; Tetrodotoxin

1997
Tachykinins may mediate capsaicin-induced, but not vagally induced motility in porcine antrum.
    Peptides, 1997, Volume: 18, Issue:10

    Topics: Animals; Benzamides; Biphenyl Compounds; Capsaicin; Electric Stimulation; Gastrointestinal Motility; Muscle Contraction; Neurokinin A; Neurokinin-1 Receptor Antagonists; Piperidines; Pyloric Antrum; Receptors, Neurokinin-2; Substance P; Swine; Tachykinins; Vagus Nerve

1997
Segmental effect of spinal NK-1 receptor blockade on the pressor reflex.
    The American journal of physiology, 1998, Volume: 275, Issue:3

    Topics: Animals; Biphenyl Compounds; Blood Pressure; Cats; Female; Laminectomy; Male; Muscle Contraction; Muscle, Skeletal; Neurokinin-1 Receptor Antagonists; Receptors, Neurokinin-1; Spinal Cord; Spinal Nerve Roots

1998
In vivo signal transduction of tetrodotoxin-sensitive nociceptive responses by substance P given into the planta of the mouse hind limb.
    Cellular and molecular neurobiology, 1998, Volume: 18, Issue:5

    Topics: Action Potentials; Afferent Pathways; Animals; Biphenyl Compounds; Calcium Signaling; Egtazic Acid; Estrenes; GTP-Binding Proteins; Hindlimb; Inositol 1,4,5-Trisphosphate; Ion Transport; Male; Mice; Mice, Inbred Strains; Models, Neurological; Muscle Contraction; Neurons, Afferent; Neurotoxins; Nociceptors; Phosphatidylinositol Diacylglycerol-Lyase; Phosphodiesterase Inhibitors; Pyrrolidinones; Receptors, Neurokinin-1; Reflex; Signal Transduction; Substance P; Tetrodotoxin; Type C Phospholipases

1998
Action of substance P and interaction of calcitonin gene-related peptide and substance P on the cat antral circular muscle.
    Regulatory peptides, 1998, Oct-16, Volume: 77, Issue:1-3

    Topics: Animals; Atropine; Autoradiography; Biphenyl Compounds; Calcitonin Gene-Related Peptide; Cats; Colon; Immunohistochemistry; Muscle Contraction; Protein Binding; Pyloric Antrum; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Tetrodotoxin

1998
Pharmacological evidence that neuropeptides mediate part of the actions of scorpion venom on the guinea pig ileum.
    European journal of pharmacology, 1999, Mar-05, Volume: 368, Issue:2-3

    Topics: Animals; Atropine; Biphenyl Compounds; Guinea Pigs; Ileum; In Vitro Techniques; Indoles; Isoindoles; Muscarinic Antagonists; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Neuropeptides; Scorpion Venoms; Stereoisomerism; Substance P

1999
[Effects of tachykinin receptor antagonists on allergic asthma in guinea pigs].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1997, Volume: 32, Issue:5

    Topics: Animals; Asthma; Benzamides; Biphenyl Compounds; Bronchi; Bronchoconstriction; Female; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Ovalbumin; Piperidines; Receptors, Neurokinin-2; Receptors, Tachykinin; Trachea

1997
Effect of tachykinins on ascending and descending reflex pathway in rat small intestine.
    Acta pharmacologica Sinica, 2002, Volume: 23, Issue:4

    Topics: Afferent Pathways; Animals; Biphenyl Compounds; Efferent Pathways; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Physalaemin; Rats; Rats, Wistar; Reaction Time; Receptors, Neurokinin-2; Reflex; Substance P; Tachykinins

2002
CP-96,345 antagonism of NK1 receptors and smoke-induced protein extravasation in relation to its cardiovascular effects.
    European journal of pharmacology, 1992, Nov-10, Volume: 222, Issue:2-3

    Topics: Animals; Biphenyl Compounds; Blood Proteins; Extravasation of Diagnostic and Therapeutic Materials; Guinea Pigs; Hemodynamics; Injections, Intravenous; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Nicotiana; Plants, Toxic; Rats; Rats, Sprague-Dawley; Receptors, Neurotransmitter; Receptors, Tachykinin; Smoke; Substance P; Swine; Trachea

1992
Characterisation of NK receptors in guinea-pig urinary bladder smooth muscle: use of selective antagonists.
    European journal of pharmacology, 1992, Nov-03, Volume: 222, Issue:1

    Topics: Animals; Biphenyl Compounds; Guinea Pigs; Hypnotics and Sedatives; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Urinary Bladder

1992
Antigen-induced enhancement of noncholinergic contractile responses to vagus nerve and electrical field stimulation in guinea pig isolated trachea.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:2

    Topics: Animals; Antigens; Biphenyl Compounds; Capsaicin; Electric Stimulation; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Naloxone; Nerve Fibers; Neurokinin A; Peptide Fragments; Prostaglandin D2; Pyrilamine; Serotonin; Tetrodotoxin; Trachea; Vagus Nerve

1992
Nonadrenergic, noncholinergic contractile responses of the guinea pig hilar bronchus involve the preferential activation of tachykinin neurokinin2 receptors.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:3

    Topics: Animals; Biphenyl Compounds; Bronchi; Culture Techniques; Electric Stimulation; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Receptors, Tachykinin

1992
Tachykinin NK1 receptor in the guinea-pig isolated proximal urethra: characterization by receptor selective agonists and antagonists.
    British journal of pharmacology, 1992, Volume: 106, Issue:4

    Topics: Animals; Biphenyl Compounds; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Receptors, Neurotransmitter; Receptors, Tachykinin; Tachykinins; Urethra

1992
Antiinflammatory and analgesic activity of a non-peptide substance P receptor antagonist.
    European journal of pharmacology, 1992, Jul-07, Volume: 217, Issue:2-3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Bradykinin; Capillary Permeability; Capsaicin; Guinea Pigs; Histamine; Male; Mice; Muscle Contraction; Platelet Activating Factor; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Skin; SRS-A; Tachykinins; Ureter

1992
(+/-)-CP-96,345, a selective tachykinin NK1 receptor antagonist, has non-specific actions on neurotransmission.
    British journal of pharmacology, 1992, Volume: 107, Issue:3

    Topics: Animals; Biphenyl Compounds; Carbachol; Dinoprost; Electric Stimulation; Female; Guinea Pigs; Hypnotics and Sedatives; In Vitro Techniques; Iris; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Rabbits; Receptors, Neurotransmitter; Receptors, Tachykinin; Synaptic Transmission; Tachykinins; Vas Deferens

1992
FK 224, a novel cyclopeptide substance P antagonist with NK1 and NK2 receptor selectivity.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:1

    Topics: Animals; Binding, Competitive; Biphenyl Compounds; Cell Membrane; Cerebral Cortex; Guinea Pigs; Lung; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptides, Cyclic; Rats; Rats, Inbred Strains; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P

1992
CP-96,345, a non-peptide antagonist of substance P: I. Effects on the actions mediated by substance P and related tachykinins on the guinea-pig ileum and rabbit jejunum.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 346, Issue:3

    Topics: Animals; Biphenyl Compounds; Capsaicin; Electric Stimulation; Guinea Pigs; Hexamethonium Compounds; Histamine; Ileum; In Vitro Techniques; Jejunum; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Peristalsis; Rabbits; Stereoisomerism; Substance P; Tachykinins

1992
Tachykinin receptors in rabbit airways--characterization by functional, autoradiographic and binding studies.
    British journal of pharmacology, 1992, Volume: 107, Issue:2

    Topics: Amino Acid Sequence; Animals; Autoradiography; Binding Sites; Biphenyl Compounds; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Peptides, Cyclic; Rabbits; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Tachykinins; Trachea

1992
A potent nonpeptide antagonist of the substance P (NK1) receptor.
    Science (New York, N.Y.), 1991, Jan-25, Volume: 251, Issue:4992

    Topics: Animals; Binding, Competitive; Biphenyl Compounds; Carotid Arteries; Cattle; Dogs; Molecular Structure; Muscle Contraction; Muscle Relaxation; Rabbits; Rats; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Salivation; Stereoisomerism; Substance P

1991
Comparison of spantide II and CP-96,345 for blockade of tachykinin-evoked contractions of smooth muscle.
    Biochemical and biophysical research communications, 1991, Jul-15, Volume: 178, Issue:1

    Topics: Analgesics; Animals; Biphenyl Compounds; Female; In Vitro Techniques; Iris; Male; Muscle Contraction; Muscle, Smooth; Rabbits; Substance P; Tachykinins

1991