cp 96345 has been researched along with Muscle Contraction in 52 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 47 (90.38) | 18.2507 |
2000's | 3 (5.77) | 29.6817 |
2010's | 2 (3.85) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Cardoso, CRB; de Oliveira, AM; do Vale, BN; Gimenes, LR; Gomes, MS; Moreira, JD; Pernomian, L | 1 |
Li, C; Micci, MA; Murthy, KS; Pasricha, PJ | 1 |
Chien, CT; Hsu, SM; Lai, MK; Lin, TB; Yu, HJ | 1 |
Gallantine, EL; Meert, TF | 1 |
Longmore, J; Razzaque, Z | 1 |
Hay, DW; Hubbard, WC; Undem, BJ | 1 |
Akkermans, LM; Briejer, MR; Lefebvre, RA; Meulemans, AL; Schuurkes, JA | 1 |
Boccio, D; Carruette, A; Garret, C; Montier, F; Moussaoui, S | 1 |
Hill, RG; Longmore, J; Razzaque, Z; Shaw, D | 1 |
Corsi, M; Gaviraghi, G; Oliosi, B; Palea, S; Pietra, C; Sugg, E; Trist, DG; Van Amsterdam, FT | 1 |
Gomi, Y; Mizuno, K; Suzuki, N | 1 |
Barthó, L; Lefebvre, R | 1 |
Lefebvre, RA; Smits, GJ | 1 |
Killingsworth, CR; Shore, SA | 1 |
Giuliani, S; Maggi, CA; Meini, S; Patacchini, R | 1 |
Iwata, T; Kamiya, H; Matsumoto, H; Ohno, M; Saito, R; Shimohigashi, Y; Takano, Y | 1 |
Bertrand, C; Bunnett, NW; Debas, HT; Geppetti, P; Huber, O; Nadel, JA; Pellegrini, CA | 1 |
Honda, K; Kamiya, H; Nakayama, Y; Saigo, A; Saito, R; Takano, Y | 1 |
Giachetti, A; Giuliani, S; Maggi, CA; Patacchini, R | 1 |
Bartho, L; Giuliani, S; Maggi, CA; Santicioli, P | 1 |
Birder, LA; Fukuoka, H; Kawatani, M; Matsumoto, G; Misaki, A; Suzuki, S; Yoshiyama, M | 1 |
Boyle, SJ; Guard, S; McKnight, AT; Tang, KW; Watling, KJ; Woodruff, GN | 1 |
Carraway, RE; Mitra, SP | 1 |
Hodgson, WC; Hopkins, BJ; Sutherland, SK | 1 |
Hill, JM; Kaufman, MP; Pickar, JG | 1 |
Håkanson, R; Strichartz, GR; Tung, SR; Wang, ZY | 1 |
Benoit, PA; Constantine, JW; Knight, DR; Lebel, WS; Wolfgang, EA; Woody, HA | 1 |
Bertrand, C; Bunnett, NW; Debas, HT; Geppetti, P; Huber, O; Nadel, JA; Nakazato, P; Pellegrini, CA | 1 |
Barnes, JC; Hawcock, AB | 1 |
Briejer, MR; Schuurkes, JA | 1 |
Galligan, JJ; Yunker, AM | 1 |
Cirillo, R; Conte, B; Manzini, S; Parlani, M | 1 |
Gustafsson, LE; Olgart, C; Wiklund, NP | 1 |
Holst, JJ; Rasmussen, TN; Schmidt, PT | 1 |
Hand, GA; Wilson, LB | 1 |
Inoue, M; Nakayamada, H; Tokuyama, S; Ueda, H | 1 |
Broussard, DL; Feng, HS; Ouyang, A | 1 |
Freire-Maia, L; Leite, R; Matos, IM; Teixeira, MM | 1 |
Lu, ZY; Wei, EQ; Zhang, WP | 1 |
Allescher, HD; Hahn, A; Storr, M | 1 |
Clingan, CA; Delay-Goyet, P; Franco-Cereceda, A; Gonsalves, SF; Lowe, JA; Lundberg, JM | 1 |
Hill, RG; Longmore, J | 1 |
Ellis, JL; Undem, BJ | 1 |
Buckner, CK; Renzetti, LM; Shenvi, A | 1 |
Maggi, CA; Patacchini, R | 1 |
Hess, HJ; Kanai, Y; Lowe, JA; Nagahisa, A; Suga, O; Taniguchi, K; Tsuchiya, M | 1 |
Håkanson, R; Wang, ZY | 1 |
Fujii, T; Kiyotoh, S; Maeda, Y; Morimoto, H; Murai, M; Nishikawa, M; Yamaoka, M | 1 |
Griesbacher, T; Legat, FJ; Lembeck, F | 1 |
Alouan, LA; Armour, CL; Badgery-Parker, T; Black, JL; Burcher, E; Diment, LM; Johnson, PR | 1 |
Constantine, JW; Desai, MC; Drozda, SE; Lebel, WS; Longo, KP; Lowe, JA; Snider, RM; Spencer, RW; Vinick, FJ; Woody, HA | 1 |
Folkers, K; Håkanson, R; Wang, ZY | 1 |
52 other study(ies) available for cp 96345 and Muscle Contraction
Article | Year |
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Endothelinergic Contractile Hyperreactivity in Rat Contralateral Carotid to Balloon Injury: Integrated Role for ET
Topics: Acridines; Animals; Biphenyl Compounds; Calcium; Carotid Arteries; Carotid Artery Injuries; Cyclic N-Oxides; Endothelin-1; Endothelium; Male; Muscle Contraction; Oligopeptides; Peptides, Cyclic; Piperidines; Rats; Receptor, Endothelin A; Spin Labels; Superoxides; Vasoconstriction | 2017 |
Substance P is essential for maintaining gut muscle contractility: a novel role for coneurotransmission revealed by botulinum toxin.
Topics: Acetylcholine; Animals; Biphenyl Compounds; Botulinum Toxins; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Myosin Light Chains; Pyloric Antrum; Pylorus; Rats; Receptors, Neurokinin-1; Substance P | 2014 |
Substance P via NK1 receptor facilitates hyperactive bladder afferent signaling via action of ROS.
Topics: Animals; Benzamides; Biphenyl Compounds; Cell Adhesion Molecules; Dose-Response Relationship, Drug; Drug Administration Routes; Electric Stimulation; Female; Free Radical Scavengers; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Pelvis; Piperidines; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, Neurokinin-1; Reflex, Abnormal; Signal Transduction; Sodium Chloride; Substance P; Superoxide Dismutase; Urinary Bladder; Urinary Bladder, Neurogenic; Urination; Visceral Afferents | 2003 |
Attenuation of the gerbil writhing response by mu-, kappa- and delta-opioids, and NK-1, -2 and -3 receptor antagonists.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Abdomen; Acetic Acid; Analgesics, Opioid; Animals; Behavior, Animal; Biphenyl Compounds; Butanols; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Fentanyl; Gerbillinae; Malates; Morphine; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Pain Measurement; Piperidines; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tetrazoles | 2004 |
Comparison of the effects of (+/-) CP 96,345 and L-668,169 on neurokinin receptor mediated responses in rat and guinea-pig isolated tissues.
Topics: Animals; Biphenyl Compounds; Eledoisin; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Neurokinin-1 Receptor Antagonists; Organ Specificity; Peptide Fragments; Peptides, Cyclic; Portal Vein; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Species Specificity; Substance P; Urinary Bladder | 1993 |
Relative contributions of direct and indirect mechanisms mediating endothelin-induced contraction of guinea-pig trachea.
Topics: Animals; Benzamides; Biphenyl Compounds; Capsaicin; Dicarboxylic Acids; Endothelins; Epithelium; Guinea Pigs; Histamine Release; In Vitro Techniques; Kinetics; Leukotriene Antagonists; Male; Muscle Contraction; Neurokinin A; Piperidines; Prostaglandins; Receptors, Tachykinin; SRS-A; Tetrodotoxin; Trachea | 1993 |
Substance P-induced contractions of the guinea-pig proximal colon through stimulation of post-junctional tachykinin NK1 receptors.
Topics: Androstanes; Androstenes; Animals; Benzimidazoles; Biphenyl Compounds; Colon; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Neuromuscular Junction; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P | 1993 |
Antagonism of substance P and related peptides by RP 67580 and CP-96,345, at tachykinin NK1 receptor sites, in the rat urinary bladder.
Topics: Animals; Biphenyl Compounds; Blood Proteins; Female; Hypnotics and Sedatives; In Vitro Techniques; Indoles; Isoindoles; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P; Urinary Bladder | 1994 |
Differences in the effects of NK1-receptor antagonists, (+/-)-CP 96,345 and CP 99,994, on agonist-induced responses in guinea-pig trachea.
Topics: Animals; Biphenyl Compounds; Guinea Pigs; In Vitro Techniques; Indoles; Isoindoles; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Pyrrolidonecarboxylic Acid; Substance P; Trachea | 1994 |
A further analysis of the contraction induced by activation of cholecystokinin A receptors in guinea pig isolated ileum longitudinal muscle-myenteric plexus.
Topics: Animals; Atropine; Biphenyl Compounds; Drug Interactions; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Neuromuscular Junction; Peptide Fragments; Peptides, Cyclic; Physalaemin; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Substance P; Tetragastrin; Tetrodotoxin | 1994 |
Tachykinin-induced contractions in the circular muscle of guinea pig ileum.
Topics: Animals; Atropine; Biphenyl Compounds; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Hypnotics and Sedatives; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Peptides, Cyclic; Rats; Structure-Activity Relationship; Substance P; Tachykinins; Tetrodotoxin | 1994 |
Nitric oxide induces acetylcholine-mediated contractions in the guinea-pig small intestine.
Topics: Acetylcholine; Animals; Atropine; Biphenyl Compounds; Dose-Response Relationship, Drug; Guinea Pigs; Hexamethonium; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Substance P; Tetrodotoxin | 1994 |
Tachykinin receptors involved in the contractile effect of the natural tachykinins in the rat gastric fundus.
Topics: Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Female; Gastric Fundus; Indoles; Isoindoles; Male; Methacholine Chloride; Muscle Contraction; Neurokinin A; Neurokinin B; Peptide Fragments; Peptides, Cyclic; Rats; Receptors, Tachykinin; Substance P; Tachykinins | 1994 |
Tachykinin receptors mediating contraction of guinea pig lung strips.
Topics: Acetylcholine; Animals; Benzamides; Biphenyl Compounds; Dipeptides; Guinea Pigs; In Vitro Techniques; Lung; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Tachykinin; Substance P; Trachea | 1995 |
Evidence for the presence of a septide-sensitive tachykinin receptor in the circular muscle of the guinea-pig ileum.
Topics: Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscles; Neurokinin A; Peptide Fragments; Pyrrolidonecarboxylic Acid; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Tachykinins | 1993 |
Receptor-mediated specific biological activity of a beta-amyloid protein fragment for NK-1 substance P receptors.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Kinetics; Male; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P | 1993 |
Tachykinins contract the circular muscle of the human esophageal body in vitro via NK2 receptors.
Topics: Adolescent; Adult; Aged; Atropine; Benzamides; Biphenyl Compounds; Carbachol; Dose-Response Relationship, Drug; Esophagus; Glycopeptides; Humans; Isometric Contraction; Middle Aged; Muscle Contraction; Muscle, Smooth; Neprilysin; Neurokinin A; Neurokinin B; Piperidines; Receptors, Tachykinin; Substance P; Tachykinins; Tetrodotoxin | 1993 |
Role of NK-1 receptor in central cardiovascular regulation in rats: studies on a novel non-peptide antagonist, CP-96,345, of substance P NK-1 receptor.
Topics: Animals; Biphenyl Compounds; Blood Pressure; Cerebral Ventricles; Heart Rate; Hypnotics and Sedatives; Injections, Intraventricular; Male; Muscle Contraction; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Rats; Receptors, Neurokinin-1; Substance P; Tachykinins; Vas Deferens | 1993 |
In vivo and in vitro activity of SR 48,968, a non-peptide tachykinin NK-2 receptor antagonist.
Topics: Animals; Benzamides; Biphenyl Compounds; Blood Pressure; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Piperidines; Rats; Receptors, Neurokinin-2; Saliva; Substance P; Sulfones; Urinary Bladder | 1993 |
Tachykinin NK-1 and NK-2 receptors in the circular muscle of the guinea-pig proximal colon.
Topics: Animals; Benzamides; Biphenyl Compounds; Colon; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Peptides, Cyclic; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Sulfones; Tetrodotoxin | 1993 |
Intrathecal administration of NK1 receptor antagonist, CP96345, inhibits the micturition reflex in the rat.
Topics: Animals; Biphenyl Compounds; Female; Injections, Spinal; Male; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Neurokinin-1; Reflex; Spinal Cord; Substance P; Urinary Bladder; Urination | 1993 |
The interaction of the NK1 receptor antagonist CP-96,345 with L-type calcium channels and its functional consequences.
Topics: Animals; Biphenyl Compounds; Calcium Channels; Cerebral Cortex; Diltiazem; Guinea Pigs; In Vitro Techniques; Male; Membranes; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Neurokinin-1 Receptor Antagonists; Nimodipine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Stereoisomerism; Substance P; Succinimides; Trachea | 1993 |
Binding and biologic activity of neurotensin in guinea pig ileum.
Topics: Adenine Nucleotides; Amino Acid Sequence; Animals; Atropine; Biphenyl Compounds; Cell Membrane; Dose-Response Relationship, Drug; Dynorphins; Guanine Nucleotides; Guinea Pigs; Hydrogen-Ion Concentration; Hypnotics and Sedatives; Ileum; In Vitro Techniques; Kinetics; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neostigmine; Neurotensin; Physostigmine; Receptors, Neurotensin; Structure-Activity Relationship | 1994 |
Pharmacological studies of stonefish (Synanceja trachynis) venom.
Topics: Animals; Biphenyl Compounds; Blood Pressure; Captopril; Chromones; Dose-Response Relationship, Drug; Fish Venoms; Fishes; Guinea Pigs; Heptanoic Acids; Histamine; Ileum; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Male; Mecamylamine; Muscle Contraction; Muscle, Smooth; Phospholipases A; Phospholipases A2; Quinacrine; Rats; Receptors, Thromboxane; Serotonin; SRS-A; Tetrazoles; Vas Deferens | 1994 |
Blockade of non-NMDA receptors attenuates reflex pressor response to static contraction.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biphenyl Compounds; Blood Pressure; Cats; Heart Rate; Hypnotics and Sedatives; Injections, Spinal; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Piperazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Time Factors | 1994 |
Non-specific actions of the non-peptide tachykinin receptor antagonists, CP-96,345, RP 67580 and SR 48968, on neurotransmission.
Topics: Action Potentials; Anesthetics, Local; Animals; Benzamides; Biphenyl Compounds; Bupivacaine; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Indoles; Iris; Isoindoles; Male; Muscle Contraction; Muscle, Smooth; Piperidines; Procaine; Rabbits; Rana catesbeiana; Receptors, Tachykinin; Sciatic Nerve; Synaptic Transmission; Vas Deferens | 1994 |
Cardiovascular effects of CP-96,345, a non-peptide blocker of tachykinin NK1 receptors.
Topics: Animals; Biphenyl Compounds; Blood Pressure; Calcium; Calcium Channel Blockers; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neurokinin-1 Receptor Antagonists; Portal Vein; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1994 |
Tachykinins mediate contraction of the human lower esophageal sphincter in vitro via activation of NK2 receptors.
Topics: Benzamides; Biphenyl Compounds; Dose-Response Relationship, Drug; Esophagogastric Junction; Glycopeptides; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Neprilysin; Neurokinin A; Neurokinin B; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Tachykinins | 1993 |
Pharmacological characterization of the contractile responses to angiotensin analogues in guinea-pig isolated longitudinal muscle of small intestine.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atropine; Biphenyl Compounds; Guinea Pigs; Hypnotics and Sedatives; Imidazoles; In Vitro Techniques; Intestine, Small; Losartan; Male; Muscle Contraction; Muscle, Smooth; Pyridines; Tetrazoles; Tetrodotoxin | 1993 |
5-HT3 and 5-HT4 receptors and cholinergic and tachykininergic neurotransmission in the guinea-pig proximal colon.
Topics: Animals; Biphenyl Compounds; Colon; Dioxanes; Dose-Response Relationship, Drug; Drug Interactions; Female; Granisetron; Guinea Pigs; In Vitro Techniques; Interneurons; Male; Motor Neurons; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists | 1996 |
Endogenous NO inhibits NANC but not cholinergic neurotransmission to circular muscle of guinea pig ileum.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apamin; Bethanechol; Biphenyl Compounds; Electric Stimulation; Guanethidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Neurokinin-1 Receptor Antagonists; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Scopolamine; Substance P; Synaptic Transmission; Tetrodotoxin; Vasoactive Intestinal Peptide | 1996 |
Characterization of tachykinin NK2 receptor on dog proximal colon. Antagonism by MEN 10,627 and SR 48,968.
Topics: Animals; Benzamides; Biphenyl Compounds; Colon; Dogs; Dose-Response Relationship, Drug; Gastrointestinal Motility; In Vitro Techniques; Muscle Contraction; Peptides, Cyclic; Piperidines; Receptors, Neurokinin-2 | 1996 |
Blockade of nitric oxide-evoked smooth muscle contractions by an inhibitor of guanylyl cyclase.
Topics: Animals; Biphenyl Compounds; Enzyme Inhibitors; Guanylate Cyclase; Guinea Pigs; In Vitro Techniques; Intestine, Small; Male; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Nitric Oxide; Signal Transduction; Substance P; Tetrodotoxin | 1997 |
Tachykinins may mediate capsaicin-induced, but not vagally induced motility in porcine antrum.
Topics: Animals; Benzamides; Biphenyl Compounds; Capsaicin; Electric Stimulation; Gastrointestinal Motility; Muscle Contraction; Neurokinin A; Neurokinin-1 Receptor Antagonists; Piperidines; Pyloric Antrum; Receptors, Neurokinin-2; Substance P; Swine; Tachykinins; Vagus Nerve | 1997 |
Segmental effect of spinal NK-1 receptor blockade on the pressor reflex.
Topics: Animals; Biphenyl Compounds; Blood Pressure; Cats; Female; Laminectomy; Male; Muscle Contraction; Muscle, Skeletal; Neurokinin-1 Receptor Antagonists; Receptors, Neurokinin-1; Spinal Cord; Spinal Nerve Roots | 1998 |
In vivo signal transduction of tetrodotoxin-sensitive nociceptive responses by substance P given into the planta of the mouse hind limb.
Topics: Action Potentials; Afferent Pathways; Animals; Biphenyl Compounds; Calcium Signaling; Egtazic Acid; Estrenes; GTP-Binding Proteins; Hindlimb; Inositol 1,4,5-Trisphosphate; Ion Transport; Male; Mice; Mice, Inbred Strains; Models, Neurological; Muscle Contraction; Neurons, Afferent; Neurotoxins; Nociceptors; Phosphatidylinositol Diacylglycerol-Lyase; Phosphodiesterase Inhibitors; Pyrrolidinones; Receptors, Neurokinin-1; Reflex; Signal Transduction; Substance P; Tetrodotoxin; Type C Phospholipases | 1998 |
Action of substance P and interaction of calcitonin gene-related peptide and substance P on the cat antral circular muscle.
Topics: Animals; Atropine; Autoradiography; Biphenyl Compounds; Calcitonin Gene-Related Peptide; Cats; Colon; Immunohistochemistry; Muscle Contraction; Protein Binding; Pyloric Antrum; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Tetrodotoxin | 1998 |
Pharmacological evidence that neuropeptides mediate part of the actions of scorpion venom on the guinea pig ileum.
Topics: Animals; Atropine; Biphenyl Compounds; Guinea Pigs; Ileum; In Vitro Techniques; Indoles; Isoindoles; Muscarinic Antagonists; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Neuropeptides; Scorpion Venoms; Stereoisomerism; Substance P | 1999 |
[Effects of tachykinin receptor antagonists on allergic asthma in guinea pigs].
Topics: Animals; Asthma; Benzamides; Biphenyl Compounds; Bronchi; Bronchoconstriction; Female; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Ovalbumin; Piperidines; Receptors, Neurokinin-2; Receptors, Tachykinin; Trachea | 1997 |
Effect of tachykinins on ascending and descending reflex pathway in rat small intestine.
Topics: Afferent Pathways; Animals; Biphenyl Compounds; Efferent Pathways; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Physalaemin; Rats; Rats, Wistar; Reaction Time; Receptors, Neurokinin-2; Reflex; Substance P; Tachykinins | 2002 |
CP-96,345 antagonism of NK1 receptors and smoke-induced protein extravasation in relation to its cardiovascular effects.
Topics: Animals; Biphenyl Compounds; Blood Proteins; Extravasation of Diagnostic and Therapeutic Materials; Guinea Pigs; Hemodynamics; Injections, Intravenous; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Nicotiana; Plants, Toxic; Rats; Rats, Sprague-Dawley; Receptors, Neurotransmitter; Receptors, Tachykinin; Smoke; Substance P; Swine; Trachea | 1992 |
Characterisation of NK receptors in guinea-pig urinary bladder smooth muscle: use of selective antagonists.
Topics: Animals; Biphenyl Compounds; Guinea Pigs; Hypnotics and Sedatives; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Urinary Bladder | 1992 |
Antigen-induced enhancement of noncholinergic contractile responses to vagus nerve and electrical field stimulation in guinea pig isolated trachea.
Topics: Animals; Antigens; Biphenyl Compounds; Capsaicin; Electric Stimulation; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Naloxone; Nerve Fibers; Neurokinin A; Peptide Fragments; Prostaglandin D2; Pyrilamine; Serotonin; Tetrodotoxin; Trachea; Vagus Nerve | 1992 |
Nonadrenergic, noncholinergic contractile responses of the guinea pig hilar bronchus involve the preferential activation of tachykinin neurokinin2 receptors.
Topics: Animals; Biphenyl Compounds; Bronchi; Culture Techniques; Electric Stimulation; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Receptors, Tachykinin | 1992 |
Tachykinin NK1 receptor in the guinea-pig isolated proximal urethra: characterization by receptor selective agonists and antagonists.
Topics: Animals; Biphenyl Compounds; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Receptors, Neurotransmitter; Receptors, Tachykinin; Tachykinins; Urethra | 1992 |
Antiinflammatory and analgesic activity of a non-peptide substance P receptor antagonist.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Bradykinin; Capillary Permeability; Capsaicin; Guinea Pigs; Histamine; Male; Mice; Muscle Contraction; Platelet Activating Factor; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Skin; SRS-A; Tachykinins; Ureter | 1992 |
(+/-)-CP-96,345, a selective tachykinin NK1 receptor antagonist, has non-specific actions on neurotransmission.
Topics: Animals; Biphenyl Compounds; Carbachol; Dinoprost; Electric Stimulation; Female; Guinea Pigs; Hypnotics and Sedatives; In Vitro Techniques; Iris; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Rabbits; Receptors, Neurotransmitter; Receptors, Tachykinin; Synaptic Transmission; Tachykinins; Vas Deferens | 1992 |
FK 224, a novel cyclopeptide substance P antagonist with NK1 and NK2 receptor selectivity.
Topics: Animals; Binding, Competitive; Biphenyl Compounds; Cell Membrane; Cerebral Cortex; Guinea Pigs; Lung; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptides, Cyclic; Rats; Rats, Inbred Strains; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P | 1992 |
CP-96,345, a non-peptide antagonist of substance P: I. Effects on the actions mediated by substance P and related tachykinins on the guinea-pig ileum and rabbit jejunum.
Topics: Animals; Biphenyl Compounds; Capsaicin; Electric Stimulation; Guinea Pigs; Hexamethonium Compounds; Histamine; Ileum; In Vitro Techniques; Jejunum; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Peristalsis; Rabbits; Stereoisomerism; Substance P; Tachykinins | 1992 |
Tachykinin receptors in rabbit airways--characterization by functional, autoradiographic and binding studies.
Topics: Amino Acid Sequence; Animals; Autoradiography; Binding Sites; Biphenyl Compounds; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Peptides, Cyclic; Rabbits; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Tachykinins; Trachea | 1992 |
A potent nonpeptide antagonist of the substance P (NK1) receptor.
Topics: Animals; Binding, Competitive; Biphenyl Compounds; Carotid Arteries; Cattle; Dogs; Molecular Structure; Muscle Contraction; Muscle Relaxation; Rabbits; Rats; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Salivation; Stereoisomerism; Substance P | 1991 |
Comparison of spantide II and CP-96,345 for blockade of tachykinin-evoked contractions of smooth muscle.
Topics: Analgesics; Animals; Biphenyl Compounds; Female; In Vitro Techniques; Iris; Male; Muscle Contraction; Muscle, Smooth; Rabbits; Substance P; Tachykinins | 1991 |