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cp 96345 and Inflammation

cp 96345 has been researched along with Inflammation in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (75.00)18.2507
2000's4 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Elfert, A; He, ZJ; Micci, MA; Pasricha, PJ; Winston, JH; Xiao, SY; Yusuf, TE1
Bittner, A; Brueck, W; Gronen, F; Hemmer, B; Nessler, S; Schlegel, K; Sommer, N; Stadelmann, C1
Bhatia, M; Ramnath, RD; Sun, J1
Nourshargh, S; Walsh, DT; Weg, VB; Williams, TJ1
Bordner, J; Bryce, DK; Drozda, SE; Jackson, ER; Longo, KP; Lowe, JA; McLean, S; Morrone, J; Snider, RM; Zorn, SH1
Berge, OG; Ståhlberg, M1
Asai, R; Kanai, Y; Murase, A; Nagahisa, A; Nakagaki, T; Shieh, TC; Taniguchi, K; Tsuchiya-Nakagaki, M2
Lundberg, JM1
Bertrand, C; Foresi, A; Geppetti, P; Graf, PD; Nadel, JA1
Gao, GC; Wei, ET1
Dubner, R; Iadarola, MJ; Ren, K1
Traub, RJ1
Astolfi, M; Barnes, PJ; Evangelista, S; Mak, JC; Manzini, S; Zhang, XL1
Farber, EM; Raychaudhuri, SP1
Donnerer, J; Lembeck, F; Nagahisa, A; Tsuchiya, M1

Reviews

1 review(s) available for cp 96345 and Inflammation

ArticleYear
Discovery of CP-96,345 and its characterization in disease models involving substance P.
    Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2

    Topics: Analgesics; Animals; Asthma; Binding, Competitive; Biphenyl Compounds; Disease Models, Animal; Inflammation; Pain; Receptors, Neurokinin-2; Substance P

1993

Other Studies

15 other study(ies) available for cp 96345 and Inflammation

ArticleYear
Intraductal administration of an NK1 receptor antagonist attenuates the inflammatory response to retrograde infusion of radiological contrast in rats: implications for the pathogenesis and prevention of ERCP-induced pancreatitis.
    Pancreas, 2003, Volume: 27, Issue:1

    Topics: Amylases; Animals; Biphenyl Compounds; Cholangiopancreatography, Endoscopic Retrograde; Contrast Media; Edema; Endocytosis; Inflammation; Male; Neurokinin-1 Receptor Antagonists; Pancreas; Pancreatitis; Peroxidase; Rats; Rats, Sprague-Dawley

2003
Suppression of autoimmune encephalomyelitis by a neurokinin-1 receptor antagonist--a putative role for substance P in CNS inflammation.
    Journal of neuroimmunology, 2006, Volume: 179, Issue:1-2

    Topics: Adoptive Transfer; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Blood-Brain Barrier; Central Nervous System; Cytokines; Encephalomyelitis, Autoimmune, Experimental; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Immunohistochemistry; Inflammation; Intercellular Adhesion Molecule-1; Mice; Neurokinin-1 Receptor Antagonists; Substance P; T-Lymphocytes; Vascular Cell Adhesion Molecule-1

2006
Neuropeptide substance P upregulates chemokine and chemokine receptor expression in primary mouse neutrophils.
    American journal of physiology. Cell physiology, 2007, Volume: 293, Issue:2

    Topics: Active Transport, Cell Nucleus; Animals; Biphenyl Compounds; CD11b Antigen; Cells, Cultured; Chemokine CCL3; Chemokine CCL4; Chemokine CXCL2; Chemokines; Chemokines, CC; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; I-kappa B Proteins; Inflammation; Macrophage Inflammatory Proteins; Male; Mice; Neuroimmunomodulation; Neutrophils; Nitriles; Receptors, CCR1; Receptors, Chemokine; Receptors, Interleukin-8B; Receptors, Neurokinin-1; Recombinant Proteins; RNA, Messenger; Signal Transduction; Substance P; Sulfones; Transcription Factor RelA; Up-Regulation

2007
Substance P-induced inflammatory responses in guinea-pig skin: the effect of specific NK1 receptor antagonists and the role of endogenous mediators.
    British journal of pharmacology, 1995, Volume: 114, Issue:7

    Topics: Animals; Antibodies, Monoclonal; Biphenyl Compounds; Chlorpheniramine; Dihydropyridines; Dose-Response Relationship, Drug; Edema; Female; Guinea Pigs; Imidazoles; Indoles; Inflammation; Isoindoles; Neurokinin-1 Receptor Antagonists; Pyrans; Quinolones; Skin; Substance P; Time Factors

1995
Is the selective non-peptide NK-1 receptor antagonist CP96,345 a peripherally acting analgesic?
    Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2

    Topics: Analgesics; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Inflammation; Male; Mice; Mice, Inbred Strains; Motor Activity; Neurokinin-1 Receptor Antagonists; Substance P

1993
Non-specific activity of (+/-)CP-96,345 in models of pain and inflammation.
    Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2

    Topics: Animals; Biphenyl Compounds; Carrageenan; Dose-Response Relationship, Drug; Edema; Hyperalgesia; Hypnotics and Sedatives; Inflammation; Neurokinin-1 Receptor Antagonists; Pain; Rats; Stereoisomerism; Substance P; Time Factors; Verapamil

1993
[Effects of tachykinin antagonists on inflammation].
    Lakartidningen, 1995, Feb-08, Volume: 92, Issue:6

    Topics: Analgesics; Animals; Biphenyl Compounds; Humans; Hypnotics and Sedatives; Indoles; Inflammation; Isoindoles; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Tachykinin; Trachea

1995
Involvement of neurogenic inflammation in antigen-induced bronchoconstriction in guinea pigs.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 1

    Topics: Aerosols; Animals; Atropine; Benzamides; Biphenyl Compounds; Bronchoconstriction; Capsaicin; Glycopeptides; Guinea Pigs; Histamine; Immunization; Inflammation; Lung; Male; Neurokinin-1 Receptor Antagonists; Ovalbumin; Piperidines; Pulmonary Circulation; Receptors, Neurokinin-2; Vascular Resistance

1993
Inhibition of substance P-induced vascular leakage in rat by N-acetyl-neurotensin-(8-13).
    Regulatory peptides, 1995, Aug-22, Volume: 58, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Esophagus; Fasting; Inflammation; Male; Neurokinin-1 Receptor Antagonists; Neurotensin; Organ Specificity; Peptide Fragments; Rats; Rats, Sprague-Dawley; Skin; Substance P; Urinary Bladder

1995
An isobolographic analysis of the effects of N-methyl-D-aspartate and NK1 tachykinin receptor antagonists on inflammatory hyperalgesia in the rat.
    British journal of pharmacology, 1996, Volume: 117, Issue:1

    Topics: Androstanes; Animals; Benzimidazoles; Biphenyl Compounds; Dextrorphan; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Freund's Adjuvant; Hindlimb; Hyperalgesia; Inflammation; Male; Neurokinin-1 Receptor Antagonists; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

1996
The spinal contribution of substance P to the generation and maintenance of inflammatory hyperalgesia in the rat.
    Pain, 1996, Volume: 67, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Biphenyl Compounds; Carrageenan; Dose-Response Relationship, Drug; Foot; Formaldehyde; Hot Temperature; Hyperalgesia; Inflammation; Male; Neurokinin-1 Receptor Antagonists; Nociceptors; Pain; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P

1996
Autoradiographic mapping of pulmonary NK1 and NK2 tachykinin receptors and changes after repeated antigen challenge in guinea pigs.
    Peptides, 1996, Volume: 17, Issue:8

    Topics: Animals; Antigens; Autoradiography; Benzamides; Binding Sites; Biphenyl Compounds; Guinea Pigs; Inflammation; Lung; Male; Neurokinin-1 Receptor Antagonists; Ovalbumin; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Tissue Distribution

1996
Neuroimmunologic aspects of psoriasis.
    Cutis, 2000, Volume: 66, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Biphenyl Compounds; Humans; Immunohistochemistry; Inflammation; Injections, Intralesional; Nerve Growth Factor; Neuroimmunomodulation; Neuropeptides; Peptide T; Psoriasis; Psychoneuroimmunology; Receptors, Nerve Growth Factor; Relaxation Therapy; Skin; Stress, Psychological; Substance P

2000
Non-specific activity of (+/-)-CP-96,345 in models of pain and inflammation.
    British journal of pharmacology, 1992, Volume: 107, Issue:2

    Topics: Analysis of Variance; Animals; Binding Sites; Biphenyl Compounds; Disease Models, Animal; Edema; Inflammation; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Stereoisomerism

1992
The non-peptide tachykinin antagonist, CP-96,345, is a potent inhibitor of neurogenic inflammation.
    British journal of pharmacology, 1992, Volume: 105, Issue:3

    Topics: Animals; Biphenyl Compounds; Blood Pressure; Blood Proteins; Evans Blue; Female; Inflammation; Mustard Plant; Plant Extracts; Plant Oils; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Vasoactive Intestinal Peptide

1992